Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Xandra Owens Breakefield, Ph.D.

Co-Author

This page shows the publications co-authored by Xandra Breakefield and Ralph Weissleder.
Connection Strength

2.893
  1. Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles. Sci Rep. 2019 11 22; 9(1):17387.
    View in: PubMed
    Score: 0.217
  2. Characterization of single microvesicles in plasma from glioblastoma patients. Neuro Oncol. 2019 05 06; 21(5):606-615.
    View in: PubMed
    Score: 0.209
  3. Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles. Cell Rep. 2019 04 02; 27(1):255-268.e6.
    View in: PubMed
    Score: 0.208
  4. Multiplexed Profiling of Single Extracellular Vesicles. ACS Nano. 2018 01 23; 12(1):494-503.
    View in: PubMed
    Score: 0.191
  5. Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters. Nat Commun. 2015 May 13; 6:7029.
    View in: PubMed
    Score: 0.159
  6. Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nat Commun. 2015 May 11; 6:6999.
    View in: PubMed
    Score: 0.159
  7. Mutant sodium channel for tumor therapy. Mol Ther. 2009 May; 17(5):810-9.
    View in: PubMed
    Score: 0.103
  8. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008 Apr 23; 28(17):4406-13.
    View in: PubMed
    Score: 0.097
  9. Metabolic biotinylation of cell surface receptors for in vivo imaging. Nat Methods. 2006 May; 3(5):391-6.
    View in: PubMed
    Score: 0.085
  10. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006 Jan; 17(1):20-30.
    View in: PubMed
    Score: 0.083
  11. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005 Dec; 16(12):1367-76.
    View in: PubMed
    Score: 0.083
  12. In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis. Mol Ther. 2005 Jun; 11(6):926-31.
    View in: PubMed
    Score: 0.080
  13. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther. 2005 Mar; 11(3):435-43.
    View in: PubMed
    Score: 0.078
  14. Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression. Ann Neurol. 2005 Jan; 57(1):34-41.
    View in: PubMed
    Score: 0.077
  15. Molecular imaging of gene therapy for cancer. Gene Ther. 2004 Aug; 11(15):1175-87.
    View in: PubMed
    Score: 0.075
  16. Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy. Cancer Res. 2004 May 01; 64(9):3236-42.
    View in: PubMed
    Score: 0.074
  17. In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas. Cancer Res. 2004 Jan 01; 64(1):273-8.
    View in: PubMed
    Score: 0.072
  18. Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo. Oncogene. 2003 Oct 09; 22(44):6865-72.
    View in: PubMed
    Score: 0.071
  19. In vivo tracking of neural progenitor cell migration to glioblastomas. Hum Gene Ther. 2003 Sep 01; 14(13):1247-54.
    View in: PubMed
    Score: 0.071
  20. Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2. Neoplasia. 2002 Nov-Dec; 4(6):501-9.
    View in: PubMed
    Score: 0.067
  21. Quantitation of HSV mass distribution in a rodent brain tumor model. Gene Ther. 2000 Oct; 7(19):1648-55.
    View in: PubMed
    Score: 0.058
  22. Large and small extracellular vesicles released by glioma cells in vitro and in vivo. J Extracell Vesicles. 2020; 9(1):1689784.
    View in: PubMed
    Score: 0.054
  23. Mapping the in vivo distribution of herpes simplex virions. Hum Gene Ther. 1998 Jul 20; 9(11):1543-9.
    View in: PubMed
    Score: 0.050
  24. Targeting gene therapy vectors to CNS malignancies. J Neurovirol. 1998 Apr; 4(2):133-47.
    View in: PubMed
    Score: 0.049
  25. Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles. Sci Adv. 2018 03; 4(3):eaar2766.
    View in: PubMed
    Score: 0.048
  26. Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma. Neuro Oncol. 2018 01 22; 20(2):225-235.
    View in: PubMed
    Score: 0.048
  27. Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface. Exp Neurol. 1997 Jan; 143(1):61-9.
    View in: PubMed
    Score: 0.045
  28. Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity. Cancer Res. 2016 05 15; 76(10):2876-81.
    View in: PubMed
    Score: 0.042
  29. SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions. Science. 2016 Apr 08; 352(6282):242-6.
    View in: PubMed
    Score: 0.042
  30. Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Hum Gene Ther. 1995 Dec; 6(12):1543-52.
    View in: PubMed
    Score: 0.041
  31. Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. Nat Med. 2012 Dec; 18(12):1835-40.
    View in: PubMed
    Score: 0.033
  32. In vivo tomographic imaging of red-shifted fluorescent proteins. Biomed Opt Express. 2011 Mar 16; 2(4):887-900.
    View in: PubMed
    Score: 0.030
  33. miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell. 2008 Nov 04; 14(5):382-93.
    View in: PubMed
    Score: 0.025
  34. A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods. 2008 Feb; 5(2):171-3.
    View in: PubMed
    Score: 0.024
  35. A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. Neoplasia. 2004 Mar-Apr; 6(2):95-105.
    View in: PubMed
    Score: 0.018
  36. Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells. Cancer Gene Ther. 2001 Jul; 8(7):506-11.
    View in: PubMed
    Score: 0.015
  37. Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Am J Pathol. 1995 Dec; 147(6):1840-51.
    View in: PubMed
    Score: 0.010
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.