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profileJames Richard Lehrich, M.D.

TitleAssociate Professor of Neurology
InstitutionMassachusetts General Hospital
DepartmentNeurology
AddressMaasachusetts General Hospital
Wac-835
15 Parkman Street
Boston MA 02114
Phone617/726-3783
Fax617/724-0895
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R01NS025968     (LEHRICH, JAMES R)Apr 1, 1988 - Mar 31, 1990
NIH/NINDS
L-THREONINE ADMINISTRATION IN MULTIPLE SCLEROSIS
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Borges LF, Zervas NT, Lehrich JR. Idiopathic spinal cord herniation: a treatable cause of the Brown-Sequard syndrome--case report. Neurosurgery. 1995 May; 36(5):1028-32; discussion 1032-3. PMID: 7791969.
    View in: PubMed
  2. Weiner HL, Mackin GA, Orav EJ, Hafler DA, Dawson DM, LaPierre Y, Herndon R, Lehrich JR, Hauser SL, Turel A, et al. Intermittent cyclophosphamide pulse therapy in progressive multiple sclerosis: final report of the Northeast Cooperative Multiple Sclerosis Treatment Group. Neurology. 1993 May; 43(5):910-8. PMID: 8388090.
    View in: PubMed
  3. Hauser SL, Doolittle TH, Lopez-Bresnahan M, Shahani B, Schoenfeld D, Shih VE, Growdon J, Lehrich JR. An antispasticity effect of threonine in multiple sclerosis. Arch Neurol. 1992 Sep; 49(9):923-6. PMID: 1520082.
    View in: PubMed
  4. Doolittle TH, Myers RH, Lehrich JR, Birnbaum G, Sheremata W, Franklin GM, Nelson LM, Hauser SL. Multiple sclerosis sibling pairs: clustered onset and familial predisposition. Neurology. 1990 Oct; 40(10):1546-52. PMID: 2215946.
    View in: PubMed
  5. Logigian EL, McInnes JM, Berger AR, Busis NA, Lehrich JR, Shahani BT. Stretch-induced spinal accessory nerve palsy. Muscle Nerve. 1988 Feb; 11(2):146-50. PMID: 3343990.
    View in: PubMed
  6. Weiner HL, Hauser SL, Hafler DA, Fallis RJ, Lehrich JR, Dawson DM. The use of cyclophosphamide in the treatment of multiple sclerosis. Ann N Y Acad Sci. 1984; 436:373-81. PMID: 6099707.
    View in: PubMed
  7. Hauser SL, Dawson DM, Lehrich JR, Beal MF, Kevy SV, Weiner HL. Immunosuppression and plasmapheresis in chronic progressive multiple sclerosis. Design of a clinical trial. Arch Neurol. 1983 Oct 21; 40(11):687-90. PMID: 6354151.
    View in: PubMed
  8. Buonanno FS, Kistler JP, Lehrich JR, Noseworthy JH, New PF, Brady TJ. 1H Nuclear magnetic resonance imaging in multiple sclerosis. Neurol Clin. 1983 Aug; 1(3):757-64. PMID: 6680172.
    View in: PubMed
  9. Hauser SL, Dawson DM, Lehrich JR, Beal MF, Kevy SV, Propper RD, Mills JA, Weiner HL. Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH. N Engl J Med. 1983 Jan 27; 308(4):173-80. PMID: 6294517.
    View in: PubMed
  10. Freund H, Dienstag J, Lehrich J, Yoshimura N, Bradford RR, Rosen H, Atamian S, Slemmer E, Holroyde J, Fischer JE. Infusion of branched-chain enriched amino acid solution in patients with hepatic encephalopathy. Ann Surg. 1982 Aug; 196(2):209-20. PMID: 6284073; PMCID: PMC1352478.
  11. Lehrich JR, Couture J. Amyotrophic lateral sclerosis sera are not cytotoxic to neuroblastoma cells in tissue culture. Ann Neurol. 1978 Oct; 4(4):384. PMID: 569462.
    View in: PubMed
  12. Powell HC, Lehrich JR, Arnason BG. Electron-microscopic appearance of the DA virus, a demyelinating murine virus. J Neurol Sci. 1977 Oct; 34(1):15-23. PMID: 199712.
    View in: PubMed
  13. Hochberg FH, Lehrich JR, Arnason BG. Herpes simplex infection and experimental allergic encephalomyelitis. An experimental model system for reactivation of EAE. Neurology. 1977 Jun; 27(6):584-7. PMID: 559269.
    View in: PubMed
  14. Weiner HL, Schocket AL, Lehrich JR. Lymphocytotix antibodies in subacute sclerosing panencephalitis and amyotrophic lateral sclerosis. Lancet. 1977 May 07; 1(8019):1013-4. PMID: 67456.
    View in: PubMed
  15. Lehrich JR, Arnason BG, Hochberg FH. Demyelinative myelopathy in mice induced by the DA virus. J Neurol Sci. 1976 Oct; 29(2-4):149-60. PMID: 185333.
    View in: PubMed
  16. Lehrich JR, Arnason BG. Histocompatibility types and viral antibodies. Arch Neurol. 1976 Jun; 33(6):404-5. PMID: 180933.
    View in: PubMed
  17. Antel JP, Arnason BG, Fuller TC, Lehrich JR. Histocompatibility typing in amyotrophic lateral sclerosis. Arch Neurol. 1976 Jun; 33(6):423-5. PMID: 938267.
    View in: PubMed
  18. Hochberg FH, Lehrich JR, Richardson EP, Feorino P, Aström KE. Mononucleosis-associated subacute sclerosing panencephalitis. Acta Neuropathol. 1976 Jan 31; 34(1):33-40. PMID: 175632.
    View in: PubMed
  19. Lehrich JR, Oger J, Arnason BG. Neutralizing antibodies to poliovirus and mumps virus in amyotrophic lateral sclerosis. J Neurol Sci. 1974 Dec; 23(4):537-40. PMID: 4374516.
    View in: PubMed
  20. Arnason BG, Fuller TC, Lehrich JR, Wray SH. Histocompatibility types and measles antibodies in multiple sclerosis and optic neuritis. J Neurol Sci. 1974 Aug; 22(4):419-28. PMID: 4847303.
    View in: PubMed
  21. Oger J, Arnason BG, Pantazis N, Lehrich J, Young M. Synthesis of nerve growth factor by L and 3T3 cells in culture. Proc Natl Acad Sci U S A. 1974 Apr; 71(4):1554-8. PMID: 4524658; PMCID: PMC388269.
  22. Lehrich JR, Arnason BG, Fuller TC, Wray SH. Parainfluenza, histocompatibility, and multiple sclerosis. Association of parainfluenza antibodies and histocompatibility types in MS and optic neuritis. Arch Neurol. 1974 Apr; 30(4):327-9. PMID: 4361392.
    View in: PubMed
  23. Anderson FH, Lehrich JR. Lhermitte sign following head injury. Arch Neurol. 1973 Dec; 29(6):437-8. PMID: 4759419.
    View in: PubMed
  24. Momose KJ, Lehrich JR. Acute cerebellar infarction presenting as a posterior fossa mass. Radiology. 1973 Nov; 109(2):343-52. PMID: 4742320.
    View in: PubMed
  25. Lehrich JR, Arnason BG. Suppression of experimental allergic neuritis in rats by prior immunization with nerve in saline. Acta Neuropathol. 1971; 18(2):144-9. PMID: 5560817.
    View in: PubMed
  26. Lehrich JR, Katz M, Rorke LB, Barbanti-Brodano G, Koprowski H. Subacute sclerosing panencephalitis. Encephalitis in hamsters produced by viral agents isolated from human brain cells. Arch Neurol. 1970 Aug; 23(2):97-102. PMID: 4988096.
    View in: PubMed
  27. Lehrich JR, Winkler GF, Ojemann RG. Cerebellar infarction with brain stem compression. Diagnosis and surgical treatment. Arch Neurol. 1970 Jun; 22(6):490-8. PMID: 5439891.
    View in: PubMed
  28. Lehrich JR, Katz M, Rorke LB, Barbanti-Brodano G, Koprowski H. Subacute sclerosing panencephalitis viruses: induction of experimental encephalitis in hamsters. Trans Am Neurol Assoc. 1970; 95:51-6. PMID: 5514412.
    View in: PubMed
  29. Alford RH, Kasel JA, Lehrich JR, Knight V. Human responses to experimental infection with influenza A/Equi 2 virus. Am J Epidemiol. 1967 Jul; 86(1):185-92. PMID: 4951557.
    View in: PubMed
  30. Mann JJ, Rossen RD, Lehrich JR, Kasel JA. The effect of kaolin on immunoglobulins: an improved technique to remove the nonspecific serum inhibitor of reovirus hemagglutination. J Immunol. 1967 Jun; 98(6):1136-42. PMID: 4165228.
    View in: PubMed
  31. Lehrich JR, Kasel JA. Immunoglobulin responses to experimental human infection with adenovirus types 26 and 27. Proc Soc Exp Biol Med. 1966 Dec; 123(3):819-24. PMID: 4163621.
    View in: PubMed
  32. Lehrich JR, Kasel JA, Rossen RD. Immunoglobulin classes of neutralizing antibody formed after human inoculation with soluble adenoviral antigens. J Immunol. 1966 Nov; 97(5):654-62. PMID: 4162741.
    View in: PubMed
  33. Kasel JA, Alford RH, Lehrich JR, Banks PA, Huber M, Knight V. Adenovirus soluble antigens for human immunization: a progress report. Am Rev Respir Dis. 1966 Aug; 94(2):168-74. PMID: 4288101.
    View in: PubMed
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