Arlene Helen Sharpe, M.D., Ph.D.
Title Kolokotrones University Professor Institution Harvard Medical School Address Harvard Medical School Nrb-837 77 Avenue Louis Pasteur Boston MA 02115
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Title
Head of the Department of Immunology
Institution
Harvard Medical School

Mentoring
Characterization of the Immune Infiltrate in Renal Cell Carcinoma
Summer, 06/01/18 - 08/31/18
Investigating the evolution of the T-cell response to anti-PD-1 therapy in a mouse model
Full Time, 06/01/16 - 08/31/16

Research
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R01CA229851
(SULLIVAN, RYAN J)
May 17, 2018 - Apr 30, 2022
Abbreviated targeted therapy to improve anti-PD-1 inhibitor efficacy in melanoma
Role: Co-Principal Investigator
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U19AI133524
(SHARPE, ARLENE H.)
Jul 5, 2017 - Jun 30, 2022
Defining regulators of immunity to acute infection using CRISPR screens
Role: Principal Investigator
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P01AI106684
(RAY, ANURADHA)
May 15, 2015 - May 31, 2020
Immune Airway-Epithelial Interactions in Steroid-Refractory Severe Asthma
Role: Co-Principal Investigator
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P01AI108545
(VIGNALI, DARIO AA)
May 15, 2015 - Apr 30, 2020
Synergies among inhibitory receptors in tolerance, cancer and antiviral immunity
Role: Co-Principal Investigator
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P01AI112521
(VON ANDRIAN, ULRICH H)
Aug 15, 2014 - Jul 31, 2020
Mechanisms and Immunological Consequences of Host-Virus Interactions
Role: Co-Principal Investigator
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R01HL121363
(LICHTMAN, ANDREW H)
Feb 17, 2014 - Apr 30, 2018
Protection of the Heart by PD-1 and PD-L1
Role: Co-Principal Investigator
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U54CA163125
(FUTREAL, ANDREW ANDREW)
Sep 21, 2011 - Jul 31, 2016
Role of Tumor Stroma in Therapeutic Response and Resistance
Role: Co-Principal Investigator
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U01GM094665
(CASADEVALL, ARTURO)
Sep 30, 2010 - Jun 30, 2016
Atoms-to-Animals: Structural Genomics of Immunity
Role: Co-Principal Investigator
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R01AI081846
(SHARPE, ARLENE H.)
Mar 3, 2010 - Feb 28, 2015
Regulation of chronic viral infection by co-inhibitory pathways
Role: Principal Investigator
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R56AI081846
(SHARPE, ARLENE H.)
Jun 1, 2009 - Mar 2, 2010
Regulation of chronic viral infection by co-inhibitory pathways
Role: Principal Investigator
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P01AI078897
(VON ANDRIAN, ULRICH H)
Aug 15, 2008 - Jul 31, 2014
Anti-viral immune responses in lymph node
Role: Co-Principal Investigator
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P01AI065687
(TERHORST, CORNELIS P)
Jul 1, 2005 - Jul 31, 2018
SLAM Gene Family Controlled Pathways to SLE
Role: Co-Principal Investigator
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P01AI056299
(SHARPE, ARLENE H.)
Sep 30, 2003 - Aug 31, 2024
T Cell Costimulatory Pathways: Functions and Interactions
Role: Principal Investigator
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P01AI041584
(NADLER, LEE MARSHALL)
Sep 30, 1997 - Jul 31, 2003
INDUCTION OF HOST-SPECIFIC TOLERANCE IN ALLOGENIC BMT
Role: Co-Principal Investigator
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R01AI040614
(SHARPE, ARLENE H.)
Feb 1, 1997 - Nov 30, 2019
In vivo role of CTLA-4 in Costimulation and Autoimmunity
Role: Principal Investigator
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P01AI039671
(HAFLER, DAVID A.)
Sep 30, 1996 - Jul 31, 2022
Costimulatory Mechanisms of Autoimmunity
Role: Co-Principal Investigator
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R37AI038310
(SHARPE, ARLENE H.)
Jul 15, 1995 - Dec 31, 2016
In Vivo Function of the B7 Family of Costimulators
Role: Principal Investigator
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R01AI038310
(SHARPE, ARLENE H)
Jul 15, 1995 - Dec 31, 2005
IN VIVO FUNCTION OF THE B7 FAMILY OF COSTIMULATORS
Role: Principal Investigator
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P30AR042689
(KUPPER, THOMAS S.)
Apr 1, 1994 - Oct 13, 2011
Harvard Skin Disease Research Center
Role: Co-Principal Investigator
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P01AI035297
(ABBAS, ABUL K.)
Sep 30, 1993 - Jul 31, 2012
Immune Tolerance and Autoimmunity
Role: Co-Principal Investigator
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R01NS031065
(SHARPE, ARLENE H)
Jul 1, 1992 - Jun 30, 1997
PATHOGENESIS OF RETROVIRAL NEUROLOGIC DISEASE
Role: Principal Investigator

Bibliographic
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