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Lawler, Jack
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Jack William Lawler, Ph.D.
Title
Professor of Pathology
Institution
Beth Israel Deaconess Medical Center
Department
Pathology
Address
Beth Israel Deaconess Med Ctr
Rn 270k
99 Brookline Ave
Boston MA 02215
Phone
617/667-1694
Fax
617/667-3591
vCard
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selected publications
|
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Lawler J
. Counter regulation of tumor angiogenesis by vascular endothelial growth factor and thrombospondin-1. Semin Cancer Biol. 2022 11; 86(Pt 2):126-135.
PMID:
36191900
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Matuszewska K, Ten Kortenaar S, Pereira M, Santry LA, Petrik D, Lo KM, Bridle BW, Wootton SK,
Lawler J
, Petrik J. Addition of an Fc-IgG induces receptor clustering and increases the in vitro efficacy and in vivo anti-tumor properties of the thrombospondin-1 type I repeats (3TSR) in a mouse model of advanced stage ovarian cancer. Gynecol Oncol. 2022 01; 164(1):154-169.
PMID:
34799137
.
Citations:
1
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Morandi V, Petrik J,
Lawler J
. Endothelial Cell Behavior Is Determined by Receptor Clustering Induced by Thrombospondin-1. Front Cell Dev Biol. 2021; 9:664696.
PMID:
33869231
; PMCID:
PMC8044760
.
Citations:
2
Duquette M,
Sadow PM
,
Lawler J
,
Nucera C
. Corrigendum: Thrombospondin-1 Silencing Down-Regulates Integrin Expression Levels in Human Anaplastic Thyroid Cancer Cells With BRAFV600E: New Insights in the Host Tissue Adaptation and Homeostasis of Tumor Microenvironment. Front Endocrinol (Lausanne). 2020; 11:596223.
PMID:
33162943
; PMCID:
PMC7584128
.
Citations:
Fields:
End
Endocrinology
Yu DL, Stegelmeier AA, Chow N, Rghei AD, Matuszewska K,
Lawler J
, Bridle BW, Petrik JJ, Wootton SK. AAV-mediated expression of 3TSR inhibits tumor and metastatic lesion development and extends survival in a murine model of epithelial ovarian carcinoma. Cancer Gene Ther. 2020 05; 27(5):356-367.
PMID:
31160686
.
Citations:
4
Fields:
Gen
Genetics
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Matuszewska K, Santry LA, van Vloten JP, AuYeung AWK, Major PP,
Lawler J
, Wootton SK, Bridle BW, Petrik J. Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer. Clin Cancer Res. 2019 03 01; 25(5):1624-1638.
PMID:
30206160
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Prete A,
Lo AS
,
Sadow PM
, Bhasin SS, Antonello ZA, Vodopivec DM, Ullas S, Sims JN,
Clohessy J
,
Dvorak AM
, Sciuto T, Bhasin M, Murphy-Ullrich JE,
Lawler J
, Karumanchi SA,
Nucera C
. Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFß1 Axis. Clin Cancer Res. 2018 12 01; 24(23):6078-6097.
PMID:
30076136
; PMCID:
PMC6279578
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Kazerounian S
,
Lawler J
. Integration of pro- and anti-angiogenic signals by endothelial cells. J Cell Commun Signal. 2018 Mar; 12(1):171-179.
PMID:
29264709
; PMCID:
PMC5842194
.
Citations:
23
Lopez-Ramirez MA, Fonseca G, Zeineddine HA, Girard R, Moore T, Pham A, Cao Y, Shenkar R, de Kreuk BJ, Lagarrigue F,
Lawler J
, Glass CK, Awad IA, Ginsberg MH. Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017 Nov 06; 214(11):3331-3346.
PMID:
28970240
; PMCID:
PMC5679163
.
Citations:
41
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Desai P, Helkin A, Odugbesi A, Stein J, Bruch D,
Lawler J
, Maier KG, Gahtan V. Fluvastatin inhibits intimal hyperplasia in wild-type but not Thbs1-null mice. J Surg Res. 2017 04; 210:1-7.
PMID:
28457315
.
Citations:
2
Fields:
Gen
General Surgery
Translation:
Animals
Lawler J
. When is a thrombogenic matrix not thrombogenic? Blood. 2016 09 22; 128(12):1543-4.
PMID:
27658700
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Lopez-Dee ZP, Chittur SV, Patel H, Chinikaylo A, Lippert B, Patel B,
Lawler J
, Gutierrez LS. Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis. PLoS One. 2015; 10(10):e0139918.
PMID:
26461935
.
Citations:
9
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Sims JN,
Lawler J
. Thrombospondin-1-Based Antiangiogenic Therapy. J Ocul Pharmacol Ther. 2015 Sep; 31(7):366-70.
PMID:
26352160
.
Citations:
5
Fields:
Dru
Drug Therapy
Oph
Ophthalmology
Pha
Pharmacology
Translation:
Humans
Russell S, Duquette M, Liu J, Drapkin R,
Lawler J
, Petrik J. Combined therapy with thrombospondin-1 type I repeats (3TSR) and chemotherapy induces regression and significantly improves survival in a preclinical model of advanced stage epithelial ovarian cancer. FASEB J. 2015 Feb; 29(2):576-88.
PMID:
25395453
; PMCID:
PMC4314231
.
Citations:
27
Fields:
Bio
Biology
Phy
Physiology
Translation:
Humans
Animals
Cells
Choi SH, Tamura K, Khajuria RK, Bhere D, Nesterenko I,
Lawler J
,
Shah K
. Antiangiogenic variant of TSP-1 targets tumor cells in glioblastomas. Mol Ther. 2015 Feb; 23(2):235-43.
PMID:
25358253
; PMCID:
PMC4445617
.
Citations:
22
Fields:
Mol
Molecular Biology
The
Therapeutics
Translation:
Humans
Animals
Cells
Ndishabandi D, Duquette C, Billah GE, Reyes M, Duquette M,
Lawler J
,
Kazerounian S
. Thrombospondin-1 Modulates Actin Filament Remodeling and Cell Motility in Mouse Mammary Tumor cells in Vitro. Discoveries (Craiova). 2014 Oct-Dec; 2(4).
PMID:
26273699
; PMCID:
PMC4532438
.
Citations:
5
Sadow PM
,
Priolo C
, Nanni S, Karreth FA, Duquette M, Martinelli R, Husain A,
Clohessy J
, Kutzner H, Mentzel T, Carman CV, Farsetti A,
Henske EP
, Palescandolo E,
Macconaill LE
, Chung S, Fadda G, Lombardi CP, De Angelis AM, Durante O,
Parker JA
, Pontecorvi A,
Dvorak HF
,
Fletcher C
, Pandolfi PP,
Lawler J
,
Nucera C
. Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment. J Natl Cancer Inst. 2014 Aug; 106(8).
PMID:
25063326
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Duquette M,
Nadler M
, Okuhara D, Thompson J, Shuttleworth T,
Lawler J
. Members of the thrombospondin gene family bind stromal interaction molecule 1 and regulate calcium channel activity. Matrix Biol. 2014 Jul; 37:15-24.
PMID:
24845346
.
Citations:
19
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Dews M, Tan GS, Hultine S, Raman P, Choi J, Duperret EK,
Lawler J
, Bass A, Thomas-Tikhonenko A. Masking epistasis between MYC and TGF-ß pathways in antiangiogenesis-mediated colon cancer suppression. J Natl Cancer Inst. 2014 Apr; 106(4):dju043.
PMID:
24627270
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Bucur O, Almasan A, Nikolajczyk BS, Nicolson GL,
Lawler J
, Velculescu VE, Draghici S, Leabu M, Avram D, Bucur I, Calautti E, Calin GA, Chauhan SC, Ciubotaru M, Constantinescu SN, Datta D,
Duda DG
, Friedman MT, Galardy PJ, Harris BT, Huarte M, Khalil AM, Marchetti D, Movileanu L, Nat R,
Nucera C
, Popa-Wagner A,
Stancu AL
, Zhu S, Liehn EA. Discoveries: an innovative platform for publishing cutting-edge research discoveries in medicine, biology and chemistry. Discoveries (Craiova). 2013 Dec 31; 1(1):e1.
PMID:
32309535
; PMCID:
PMC6919543
.
Citations:
Duquette M,
Sadow PM
,
Lawler J
,
Nucera C
. Thrombospondin-1 Silencing Down-Regulates Integrin Expression Levels in Human Anaplastic Thyroid Cancer Cells with BRAF(V600E): New Insights in the Host Tissue Adaptation and Homeostasis of Tumor Microenvironment. Front Endocrinol (Lausanne). 2013; 4:189.
PMID:
24348463
.
Citations:
15
Fields:
End
Endocrinology
Qin L, Zhao D, Xu J, Ren X, Terwilliger EF,
Parangi S
,
Lawler J
,
Dvorak HF
, Zeng H. The vascular permeabilizing factors histamine and serotonin induce angiogenesis through TR3/Nur77 and subsequently truncate it through thrombospondin-1. Blood. 2013 Mar 14; 121(11):2154-64.
PMID:
23315169
; PMCID:
PMC3596973
.
Citations:
36
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Johnson CA, Kleshchenko YY, Ikejiani AO, Udoko AN, Cardenas TC, Pratap S, Duquette MA, Lima MF,
Lawler J
, Villalta F, Nde PN. Thrombospondin-1 interacts with Trypanosoma cruzi surface calreticulin to enhance cellular infection. PLoS One. 2012; 7(7):e40614.
PMID:
22808206
.
Citations:
15
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Shaik S,
Nucera C
,
Inuzuka H
, Gao D, Garnaas M,
Frechette G
, Harris L, Wan L, Fukushima H, Husain A,
Nose V
, Fadda G,
Sadow PM
,
Goessling W
,
North T
,
Lawler J
,
Wei W
. SCF(ß-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. J Exp Med. 2012 Jul 02; 209(7):1289-307.
PMID:
22711876
.
Citations:
45
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Lynch JM, Maillet M, Vanhoutte D, Schloemer A, Sargent MA, Blair NS, Lynch KA, Okada T, Aronow BJ, Osinska H, Prywes R, Lorenz JN, Mori K,
Lawler J
, Robbins J, Molkentin JD. A thrombospondin-dependent pathway for a protective ER stress response. Cell. 2012 Jun 08; 149(6):1257-68.
PMID:
22682248
.
Citations:
108
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Lawler PR,
Lawler J
. Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2. Cold Spring Harb Perspect Med. 2012 May; 2(5):a006627.
PMID:
22553494
.
Citations:
196
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Adams JC,
Lawler J
. The thrombospondins. Cold Spring Harb Perspect Biol. 2011 Oct 01; 3(10):a009712.
PMID:
21875984
.
Citations:
182
Fields:
Bio
Biology
Translation:
Humans
Animals
Cells
Seymour KA, Sadowitz B, Stein JJ,
Lawler J
, Maier KG, Gahtan V. Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated. Am J Surg. 2011 Nov; 202(5):553-7.
PMID:
21906719
.
Citations:
1
Fields:
Gen
General Surgery
Translation:
Humans
Cells
Xie L, Duncan MB, Pahler J, Sugimoto H, Martino M, Lively J, Mundel T, Soubasakos M, Rubin K, Takeda T, Inoue M,
Lawler J
, Hynes RO, Hanahan D, Kalluri R. Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9939-44.
PMID:
21622854
.
Citations:
29
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Olerud J, Mokhtari D, Johansson M, Christoffersson G,
Lawler J
, Welsh N, Carlsson PO. Thrombospondin-1: an islet endothelial cell signal of importance for ß-cell function. Diabetes. 2011 Jul; 60(7):1946-54.
PMID:
21617177
; PMCID:
PMC3121439
.
Citations:
42
Fields:
End
Endocrinology
Translation:
Animals
Cells
Tan K,
Lawler J
. The structure of the Ca²+-binding, glycosylated F-spondin domain of F-spondin - A C2-domain variant in an extracellular matrix protein. BMC Struct Biol. 2011 May 10; 11:22.
PMID:
21569239
; PMCID:
PMC3117680
.
Citations:
6
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Cells
Cursiefen C, Maruyama K, Bock F, Saban D, Sadrai Z,
Lawler J
,
Dana R
, Masli S. Thrombospondin 1 inhibits inflammatory lymphangiogenesis by CD36 ligation on monocytes. J Exp Med. 2011 May 09; 208(5):1083-92.
PMID:
21536744
.
Citations:
65
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Nucera C
,
Lawler J
,
Parangi S
. BRAF(V600E) and microenvironment in thyroid cancer: a functional link to drive cancer progression. Cancer Res. 2011 Apr 01; 71(7):2417-22.
PMID:
21447745
.
Citations:
45
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Kazerounian S
, Duquette M, Reyes MA, Lawler JT, Song K, Perruzzi C, Primo L, Khosravi-Far R, Bussolino F, Rabinovitz I,
Lawler J
. Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase. Blood. 2011 Apr 28; 117(17):4658-66.
PMID:
21378271
; PMCID:
PMC3099580
.
Citations:
32
Fields:
Hem
Hematology
Translation:
Humans
Cells
Nucera C
,
Nehs MA
, Nagarkatti SS,
Sadow PM
, Mekel M, Fischer AH, Lin PS, Bollag GE,
Lawler J
,
Hodin RA
,
Parangi S
. Targeting BRAFV600E with PLX4720 displays potent antimigratory and anti-invasive activity in preclinical models of human thyroid cancer. Oncologist. 2011; 16(3):296-309.
PMID:
21355020
.
Citations:
43
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Nucera C
,
Lawler J
,
Hodin R
,
Parangi S
. The BRAFV600E mutation: what is it really orchestrating in thyroid cancer? Oncotarget. 2010 Dec; 1(8):751-6.
PMID:
21321384
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Ezzie ME, Piper MG, Montague C, Newland CA, Opalek JM, Baran C, Ali N, Brigstock D,
Lawler J
, Marsh CB. Thrombospondin-1-deficient mice are not protected from bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2011 Apr; 44(4):556-61.
PMID:
20581099
.
Citations:
21
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Animals
Cells
Lawler J
. Megakaryocytes join the war on cancer. Blood. 2010 Jun 03; 115(22):4326-7.
PMID:
20522719
.
Citations:
Fields:
Hem
Hematology
Nucera C
, Porrello A, Antonello ZA, Mekel M,
Nehs MA
, Giordano TJ, Gerald D, Benjamin LE,
Priolo C
, Puxeddu E, Finn S, Jarzab B,
Hodin RA
, Pontecorvi A, Nose V,
Lawler J
,
Parangi S
. B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10649-54.
PMID:
20498063
.
Citations:
94
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Tan K,
Lawler J
. The interaction of Thrombospondins with extracellular matrix proteins. J Cell Commun Signal. 2009 Dec; 3(3-4):177-87.
PMID:
19830595
.
Citations:
50
Eroglu C, Allen NJ, Susman MW, O'Rourke NA, Park CY, Ozkan E, Chakraborty C, Mulinyawe SB, Annis DS, Huberman AD, Green EM,
Lawler J
, Dolmetsch R, Garcia KC, Smith SJ, Luo ZD, Rosenthal A, Mosher DF, Barres BA. Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. Cell. 2009 Oct 16; 139(2):380-92.
PMID:
19818485
.
Citations:
395
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Nucera C
,
Nehs MA
, Mekel M, Zhang X,
Hodin R
,
Lawler J
, Nose V,
Parangi S
. A novel orthotopic mouse model of human anaplastic thyroid carcinoma. Thyroid. 2009 Oct; 19(10):1077-84.
PMID:
19772429
.
Citations:
46
Fields:
End
Endocrinology
Translation:
Humans
Animals
Cells
Lawler J
. Introduction to the tumour microenvironment review series. J Cell Mol Med. 2009 Aug; 13(8A):1403-4.
PMID:
19583804
.
Citations:
6
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Zhang X,
Kazerounian S
, Duquette M, Perruzzi C, Nagy JA,
Dvorak HF
,
Parangi S
,
Lawler J
. Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level. FASEB J. 2009 Oct; 23(10):3368-76.
PMID:
19528255
.
Citations:
61
Fields:
Bio
Biology
Phy
Physiology
Translation:
Humans
Animals
Cells
Ren B, Song K,
Parangi S
, Jin T, Ye M, Humphreys R, Duquette M, Zhang X, Benhaga N,
Lawler J
, Khosravi-Far R. A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR. Cancer Res. 2009 May 01; 69(9):3856-65.
PMID:
19366809
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Sun J, Hopkins BD, Tsujikawa K, Perruzzi C,
Adini I
, Swerlick R, Bornstein P,
Lawler J
, Benjamin LE. Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina. Am J Physiol Heart Circ Physiol. 2009 May; 296(5):H1344-51.
PMID:
19304944
.
Citations:
28
Fields:
Car
Cardiology
Phy
Physiology
Translation:
Humans
Animals
Cells
Tan K, Duquette M, Joachimiak A,
Lawler J
. The crystal structure of the signature domain of cartilage oligomeric matrix protein: implications for collagen, glycosaminoglycan and integrin binding. FASEB J. 2009 Aug; 23(8):2490-501.
PMID:
19276170
.
Citations:
29
Fields:
Bio
Biology
Phy
Physiology
Translation:
Humans
Cells
Velasco P, Huegel R, Brasch J, Schröder JM, Weichenthal M, Stockfleth E, Schwarz T,
Lawler J
, Detmar M, Lange-Asschenfeldt B. The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions. J Invest Dermatol. 2009 Aug; 129(8):2022-30.
PMID:
19194474
.
Citations:
15
Fields:
Der
Dermatology
Translation:
Humans
Animals
Cells
Greenaway J, Henkin J,
Lawler J
, Moorehead R, Petrik J. ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Mol Cancer Ther. 2009 Jan; 8(1):64-74.
PMID:
19139114
.
Citations:
30
Fields:
Ant
Antineoplastic Agents
Translation:
Animals
Cells
Tan K, Duquette M, Liu JH,
Lawler J
, Wang JH. The crystal structure of the heparin-binding reelin-N domain of f-spondin. J Mol Biol. 2008 Sep 19; 381(5):1213-23.
PMID:
18602404
; PMCID:
PMC2561254
.
Citations:
10
Fields:
Mol
Molecular Biology
Translation:
Humans
Cells
Posey KL, Hankenson K, Veerisetty AC, Bornstein P,
Lawler J
, Hecht JT. Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen. Am J Pathol. 2008 Jun; 172(6):1664-74.
PMID:
18467703
; PMCID:
PMC2408425
.
Citations:
43
Fields:
Pat
Pathology
Translation:
Animals
Olerud J, Johansson M,
Lawler J
, Welsh N, Carlsson PO. Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets. Diabetes. 2008 Jul; 57(7):1870-7.
PMID:
18420490
; PMCID:
PMC2453615
.
Citations:
32
Fields:
End
Endocrinology
Translation:
Animals
Yee KO,
Connolly CM
, Duquette M,
Kazerounian S
, Washington R,
Lawler J
. The effect of thrombospondin-1 on breast cancer metastasis. Breast Cancer Res Treat. 2009 Mar; 114(1):85-96.
PMID:
18409060
.
Citations:
60
Fields:
Neo
Neoplasms
Translation:
Animals
Punekar S, Zak S, Kalter VG, Dobransky L, Punekar I,
Lawler JW
, Gutierrez LS. Thrombospondin 1 and its mimetic peptide ABT-510 decrease angiogenesis and inflammation in a murine model of inflammatory bowel disease. Pathobiology. 2008; 75(1):9-21.
PMID:
18334835
.
Citations:
31
Fields:
Pat
Pathology
Translation:
Animals
Kazerounian S, Yee KO,
Lawler J
. Thrombospondins in cancer. Cell Mol Life Sci. 2008 Mar; 65(5):700-12.
PMID:
18193162
; PMCID:
PMC2752021
.
Citations:
121
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Tan K, Duquette M, Liu JH, Shanmugasundaram K, Joachimiak A, Gallagher JT, Rigby AC, Wang JH,
Lawler J
. Heparin-induced cis- and trans-dimerization modes of the thrombospondin-1 N-terminal domain. J Biol Chem. 2008 Feb 15; 283(7):3932-41.
PMID:
18065761
.
Citations:
20
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Daniel C, Schaub K, Amann K,
Lawler J
, Hugo C. Thrombospondin-1 is an endogenous activator of TGF-beta in experimental diabetic nephropathy in vivo. Diabetes. 2007 Dec; 56(12):2982-9.
PMID:
17878288
.
Citations:
48
Fields:
End
Endocrinology
Translation:
Animals
Zhang X, Xu J,
Lawler J
, Terwilliger E,
Parangi S
. Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin. Clin Cancer Res. 2007 Jul 01; 13(13):3968-76.
PMID:
17606731
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Chen FH, Herndon ME, Patel N, Hecht JT, Tuan RS,
Lawler J
. Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan. J Biol Chem. 2007 Aug 24; 282(34):24591-8.
PMID:
17588949
.
Citations:
54
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Budhani F, Leonard KA, Bergdahl A, Gao J,
Lawler J
, Davis EC. Vascular response to intra-arterial injury in the thrombospondin-1 null mouse. J Mol Cell Cardiol. 2007 Aug; 43(2):210-4.
PMID:
17583726
; PMCID:
PMC2045697
.
Citations:
3
Fields:
Car
Cardiology
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Animals
Zhang X,
Lawler J
. Thrombospondin-based antiangiogenic therapy. Microvasc Res. 2007 Sep-Nov; 74(2-3):90-9.
PMID:
17559888
; PMCID:
PMC2100421
.
Citations:
61
Fields:
Vas
Vascular Diseases
Translation:
Humans
Animals
Cells
Greenaway J,
Lawler J
, Moorehead R, Bornstein P, Lamarre J, Petrik J. Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). J Cell Physiol. 2007 Mar; 210(3):807-18.
PMID:
17154366
; PMCID:
PMC3412056
.
Citations:
72
Fields:
Cel
Cell Biology
Phy
Physiology
Translation:
Animals
Cells
Zhang X, Connolly C, Duquette M,
Lawler J
,
Parangi S
. Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model. Cancer Lett. 2007 Mar 08; 247(1):143-9.
PMID:
16757110
; PMCID:
PMC3205930
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Zwicker JI, Peyvandi F, Palla R, Lombardi R, Canciani MT, Cairo A, Ardissino D, Bernardinelli L,
Bauer KA
,
Lawler J
, Mannucci P. The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer size. Blood. 2006 Aug 15; 108(4):1280-3.
PMID:
16684956
; PMCID:
PMC1895875
.
Citations:
22
Fields:
Hem
Hematology
Translation:
Humans
Cells
Yee KO,
Connolly CM
, Pines M,
Lawler J
. Halofuginone inhibits tumor growth in the polyoma middle T antigen mouse via a thrombospondin-1 independent mechanism. Cancer Biol Ther. 2006 Feb; 5(2):218-24.
PMID:
16418571
.
Citations:
8
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Animals
Cells
Tan K, Duquette M, Liu JH, Zhang R, Joachimiak A, Wang JH,
Lawler J
. The structures of the thrombospondin-1 N-terminal domain and its complex with a synthetic pentameric heparin. Structure. 2006 Jan; 14(1):33-42.
PMID:
16407063
; PMCID:
PMC2896259
.
Citations:
38
Fields:
Bio
Biochemistry
Bio
Biotechnology
Mol
Molecular Biology
Translation:
Humans
Cells
Ren B, Yee KO,
Lawler J
, Khosravi-Far R. Regulation of tumor angiogenesis by thrombospondin-1. Biochim Biophys Acta. 2006 Apr; 1765(2):178-88.
PMID:
16406676
.
Citations:
99
Fields:
Bio
Biochemistry
Bio
Biophysics
Translation:
Humans
Animals
Bonnefoy A, Daenens K, Feys HB, De Vos R, Vandervoort P, Vermylen J,
Lawler J
, Hoylaerts MF. Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13. Blood. 2006 Feb 01; 107(3):955-64.
PMID:
16204318
; PMCID:
PMC1895898
.
Citations:
59
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Zhang X, Galardi E, Duquette M,
Lawler J
,
Parangi S
. Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model. Clin Cancer Res. 2005 Aug 01; 11(15):5622-30.
PMID:
16061881
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Chen FH, Thomas AO, Hecht JT, Goldring MB,
Lawler J
. Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins. J Biol Chem. 2005 Sep 23; 280(38):32655-61.
PMID:
16051604
.
Citations:
59
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Frangogiannis NG, Ren G, Dewald O, Zymek P, Haudek S, Koerting A, Winkelmann K, Michael LH,
Lawler J
, Entman ML. Critical role of endogenous thrombospondin-1 in preventing expansion of healing myocardial infarcts. Circulation. 2005 Jun 07; 111(22):2935-42.
PMID:
15927970
.
Citations:
146
Fields:
Car
Cardiology
Vas
Vascular Diseases
Translation:
Animals
Cells
Ludlow A, Yee KO, Lipman R,
Bronson R
, Weinreb P, Huang X, Sheppard D,
Lawler J
. Characterization of integrin beta6 and thrombospondin-1 double-null mice. J Cell Mol Med. 2005 Apr-Jun; 9(2):421-37.
PMID:
15963261
; PMCID:
PMC6740207
.
Citations:
25
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Animals
Saumet A, Slimane MB, Lanotte M,
Lawler J
, Dubernard V. Type 3 repeat/C-terminal domain of thrombospondin-1 triggers caspase-independent cell death through CD47/alphavbeta3 in promyelocytic leukemia NB4 cells. Blood. 2005 Jul 15; 106(2):658-67.
PMID:
15784731
.
Citations:
34
Fields:
Hem
Hematology
Translation:
Humans
Cells
Isenberg JS, Calzada MJ, Zhou L, Guo N,
Lawler J
, Wang XQ, Frazier WA, Roberts DD. Endogenous thrombospondin-1 is not necessary for proliferation but is permissive for vascular smooth muscle cell responses to platelet-derived growth factor. Matrix Biol. 2005 Apr; 24(2):110-23.
PMID:
15890262
.
Citations:
23
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Zhang X, Galardi E, Duquette M, Delic M,
Lawler J
,
Parangi S
. Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model. Clin Cancer Res. 2005 Mar 15; 11(6):2337-44.
PMID:
15788685
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Sund M, Hamano Y, Sugimoto H, Sudhakar A, Soubasakos M, Yerramalla U, Benjamin LE,
Lawler J
, Kieran M, Shah A, Kalluri R. Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2934-9.
PMID:
15710885
; PMCID:
PMC549486
.
Citations:
54
Fields:
Sci
Science
Translation:
Animals
Cells
Short SM, Derrien A, Narsimhan RP,
Lawler J
,
Ingber DE
,
Zetter BR
. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol. 2005 Feb 14; 168(4):643-53.
PMID:
15716381
; PMCID:
PMC2171765
.
Citations:
61
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Christopherson KS, Ullian EM, Stokes CC, Mullowney CE, Hell JW, Agah A,
Lawler J
, Mosher DF, Bornstein P, Barres BA. Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell. 2005 Feb 11; 120(3):421-33.
PMID:
15707899
.
Citations:
695
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Shaked Y, Bertolini F, Man S,
Rogers MS
, Cervi D, Foutz T, Rawn K, Voskas D, Dumont DJ, Ben-David Y,
Lawler J
, Henkin J, Huber J, Hicklin DJ,
D'Amato RJ
, Kerbel RS. Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell. 2005 Jan; 7(1):101-11.
PMID:
15652753
.
Citations:
106
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Nör JE, Dipietro L, Murphy-Ullrich JE, Hynes RO,
Lawler J
, Polverini PJ. Activation of Latent TGF-ß1 by Thrombospondin-1 is a Major Component of Wound Repair. Oral Biosci Med. 2005; 2(2):153-161.
PMID:
21822445
.
Citations:
14
Calzada MJ, Annis DS, Zeng B, Marcinkiewicz C, Banas B,
Lawler J
, Mosher DF, Roberts DD. Identification of novel beta1 integrin binding sites in the type 1 and type 2 repeats of thrombospondin-1. J Biol Chem. 2004 Oct 01; 279(40):41734-43.
PMID:
15292271
.
Citations:
46
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Yee KO, Streit M, Hawighorst T, Detmar M,
Lawler J
. Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta. Am J Pathol. 2004 Aug; 165(2):541-52.
PMID:
15277228
; PMCID:
PMC1618557
.
Citations:
24
Fields:
Pat
Pathology
Translation:
Humans
Animals
Cells
Lawler J
, Detmar M. Tumor progression: the effects of thrombospondin-1 and -2. Int J Biochem Cell Biol. 2004 Jun; 36(6):1038-45.
PMID:
15094119
.
Citations:
87
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Cells
Adams JC,
Lawler J
. The thrombospondins. Int J Biochem Cell Biol. 2004 Jun; 36(6):961-8.
PMID:
15094109
; PMCID:
PMC2885884
.
Citations:
183
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Niu Q, Perruzzi C, Voskas D,
Lawler J
, Dumont DJ, Benjamin LE. Inhibition of Tie-2 signaling induces endothelial cell apoptosis, decreases Akt signaling, and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1. Cancer Biol Ther. 2004 Apr; 3(4):402-5.
PMID:
14739779
.
Citations:
18
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Cursiefen C, Masli S, Ng TF,
Dana MR
, Bornstein P,
Lawler J
, Streilein JW. Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis. Invest Ophthalmol Vis Sci. 2004 Apr; 45(4):1117-24.
PMID:
15037577
.
Citations:
65
Fields:
Oph
Ophthalmology
Translation:
Animals
Hamano Y, Sugimoto H, Soubasakos MA, Kieran M,
Olsen BR
,
Lawler J
, Sudhakar A, Kalluri R. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res. 2004 Mar 01; 64(5):1570-4.
PMID:
14996710
.
Citations:
53
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Wang S, Herndon ME, Ranganathan S, Godyna S,
Lawler J
, Argraves WS, Liau G. Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans. J Cell Biochem. 2004 Mar 01; 91(4):766-76.
PMID:
14991768
.
Citations:
27
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Pimanda JE, Ganderton T, Maekawa A, Yap CL,
Lawler J
, Kershaw G, Chesterman CN, Hogg PJ. Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice. J Biol Chem. 2004 May 14; 279(20):21439-48.
PMID:
14981081
.
Citations:
20
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Hochegger K, Knight S, Hugo C, Mayer G,
Lawler J
,
Mayadas TN
, Rosenkranz AR. Role of thrombospondin-1 in the autologous phase of an accelerated model of anti-glomerular basement membrane glomerulonephritis. Nephron Exp Nephrol. 2004; 96(2):e31-8.
PMID:
14988590
.
Citations:
3
Fields:
Nep
Nephrology
Translation:
Animals
Wang S, Wu Z, Sorenson CM,
Lawler J
, Sheibani N. Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration. Dev Dyn. 2003 Dec; 228(4):630-42.
PMID:
14648840
.
Citations:
66
Fields:
Ana
Anatomy
Translation:
Animals
Bocci G, Francia G, Man S,
Lawler J
, Kerbel RS. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12917-22.
PMID:
14561896
; PMCID:
PMC240719
.
Citations:
130
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Kipnes J, Carlberg AL, Loredo GA,
Lawler J
, Tuan RS, Hall DJ. Effect of cartilage oligomeric matrix protein on mesenchymal chondrogenesis in vitro. Osteoarthritis Cartilage. 2003 Jun; 11(6):442-54.
PMID:
12801484
.
Citations:
24
Fields:
Ort
Orthopedics
Rhe
Rheumatology
Translation:
Animals
Cells
Lee T, Nesselroth SM, Olson ET, Esemuede N,
Lawler J
, Sumpio BE, Gahtan V. Thrombospondin-1-induced vascular smooth muscle cell chemotaxis: the role of the type 3 repeat and carboxyl terminal domains. J Cell Biochem. 2003 Jun 01; 89(3):500-6.
PMID:
12761883
.
Citations:
2
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Animals
Cells
Gutierrez LS, Suckow M,
Lawler J
, Ploplis VA, Castellino FJ. Thrombospondin 1--a regulator of adenoma growth and carcinoma progression in the APC(Min/+) mouse model. Carcinogenesis. 2003 Feb; 24(2):199-207.
PMID:
12584168
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Animals
Yee KO, Duquette M, Ludlow A,
Lawler J
. Purification and analysis of thrombospondin-1. Curr Protoc Cell Biol. 2003 Feb; Chapter 10:Unit 10.10.
PMID:
18228414
.
Citations:
2
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Yano K, Brown LF,
Lawler J
, Miyakawa T, Detmar M. Thrombospondin-1 plays a critical role in the induction of hair follicle involution and vascular regression during the catagen phase. J Invest Dermatol. 2003 Jan; 120(1):14-9.
PMID:
12535193
.
Citations:
13
Fields:
Der
Dermatology
Translation:
Animals
Tan K, Duquette M, Liu JH, Dong Y, Zhang R, Joachimiak A,
Lawler J
, Wang JH. Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication. J Cell Biol. 2002 Oct 28; 159(2):373-82.
PMID:
12391027
; PMCID:
PMC2173040
.
Citations:
112
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Agah A, Kyriakides TR,
Lawler J
, Bornstein P. The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. Am J Pathol. 2002 Sep; 161(3):831-9.
PMID:
12213711
; PMCID:
PMC1867266
.
Citations:
135
Fields:
Pat
Pathology
Translation:
Animals
Lawler J
. Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J Cell Mol Med. 2002 Jan-Mar; 6(1):1-12.
PMID:
12003665
; PMCID:
PMC6740251
.
Citations:
203
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Animals
Cells
Miao WM, Seng WL, Duquette M, Lawler P, Laus C,
Lawler J
. Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-beta-dependent and -independent mechanisms. Cancer Res. 2001 Nov 01; 61(21):7830-9.
PMID:
11691800
.
Citations:
59
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Lawler J
, Miao WM, Duquette M, Bouck N,
Bronson RT
, Hynes RO. Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice. Am J Pathol. 2001 Nov; 159(5):1949-56.
PMID:
11696456
; PMCID:
PMC1867067
.
Citations:
37
Fields:
Pat
Pathology
Translation:
Animals
Rodriguez-Manzaneque JC, Lane TF, Ortega MA, Hynes RO,
Lawler J
, Iruela-Arispe ML. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12485-90.
PMID:
11606713
; PMCID:
PMC60080
.
Citations:
156
Fields:
Sci
Science
Translation:
Animals
Cells
Miao WM, Vasile E, Lane WS,
Lawler J
. CD36 associates with CD9 and integrins on human blood platelets. Blood. 2001 Mar 15; 97(6):1689-96.
PMID:
11238109
.
Citations:
34
Fields:
Hem
Hematology
Translation:
Humans
Cells
Nesselroth SM, Willis AI, Fuse S, Olson ET,
Lawler J
, Sumpio BE, Gahtan V. The C-terminal domain of thrombospondin-1 induces vascular smooth muscle cell chemotaxis. J Vasc Surg. 2001 Mar; 33(3):595-600.
PMID:
11241132
.
Citations:
4
Fields:
Gen
General Surgery
Vas
Vascular Diseases
Translation:
Humans
Animals
Cells
Riessen R, Fenchel M, Chen H, Axel DI, Karsch KR,
Lawler J
. Cartilage oligomeric matrix protein (thrombospondin-5) is expressed by human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2001 Jan; 21(1):47-54.
PMID:
11145932
.
Citations:
41
Fields:
Vas
Vascular Diseases
Translation:
Humans
Cells
Chen H, Herndon ME,
Lawler J
. The cell biology of thrombospondin-1. Matrix Biol. 2000 Dec; 19(7):597-614.
PMID:
11102749
.
Citations:
141
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Hofsteenge J, Huwiler KG, Macek B, Hess D,
Lawler J
, Mosher DF, Peter-Katalinic J. C-mannosylation and O-fucosylation of the thrombospondin type 1 module. J Biol Chem. 2001 Mar 02; 276(9):6485-98.
PMID:
11067851
.
Citations:
82
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Majluf-Cruz A, Manns JM, Uknis AB, Yang X, Colman RW, Harris RB, Frazier W,
Lawler J
, DeLa Cadena RA. Residues F16-G33 and A784-N823 within platelet thrombospondin-1 play a major role in binding human neutrophils: evaluation by two novel binding assays. J Lab Clin Med. 2000 Oct; 136(4):292-302.
PMID:
11039850
.
Citations:
10
Fields:
Cli
Clinical Laboratory Techniques
Med
Medicine (General)
Translation:
Humans
Cells
Lawler J
. The functions of thrombospondin-1 and-2. Curr Opin Cell Biol. 2000 Oct; 12(5):634-40.
PMID:
10978901
.
Citations:
146
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Chen H, Deere M, Hecht JT,
Lawler J
. Cartilage oligomeric matrix protein is a calcium-binding protein, and a mutation in its type 3 repeats causes conformational changes. J Biol Chem. 2000 Aug 25; 275(34):26538-44.
PMID:
10852928
.
Citations:
40
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Abdelouahed M, Ludlow A, Brunner G,
Lawler J
. Activation of platelet-transforming growth factor beta-1 in the absence of thrombospondin-1. J Biol Chem. 2000 Jun 16; 275(24):17933-6.
PMID:
10849431
.
Citations:
11
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Newton G,
Weremowicz S
,
Morton CC
, Jenkins NA, Gilbert DJ, Copeland NG,
Lawler J
. The thrombospondin-4 gene. Mamm Genome. 1999 Oct; 10(10):1010-6.
PMID:
10501972
.
Citations:
4
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Iruela-Arispe ML, Lombardo M, Krutzsch HC,
Lawler J
, Roberts DD. Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation. 1999 Sep 28; 100(13):1423-31.
PMID:
10500044
.
Citations:
111
Fields:
Car
Cardiology
Vas
Vascular Diseases
Translation:
Animals
Cells
Sipes JM, Krutzsch HC,
Lawler J
, Roberts DD. Cooperation between thrombospondin-1 type 1 repeat peptides and alpha(v)beta(3) integrin ligands to promote melanoma cell spreading and focal adhesion kinase phosphorylation. J Biol Chem. 1999 Aug 06; 274(32):22755-62.
PMID:
10428859
.
Citations:
17
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Streit M, Velasco P, Brown LF, Skobe M, Richard L, Riccardi L,
Lawler J
, Detmar M. Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas. Am J Pathol. 1999 Aug; 155(2):441-52.
PMID:
10433937
; PMCID:
PMC1866855
.
Citations:
90
Fields:
Pat
Pathology
Translation:
Humans
Animals
Cells
Eda S,
Lawler J
, Sherman IW. Plasmodium falciparum-infected erythrocyte adhesion to the type 3 repeat domain of thrombospondin-1 is mediated by a modified band 3 protein. Mol Biochem Parasitol. 1999 May 25; 100(2):195-205.
PMID:
10391381
.
Citations:
3
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Par
Parasitology
Translation:
Humans
Animals
Cells
Tucker RP, Hagios C, Chiquet-Ehrismann R,
Lawler J
, Hall RJ, Erickson CA. Thrombospondin-1 and neural crest cell migration. Dev Dyn. 1999 Apr; 214(4):312-22.
PMID:
10213387
.
Citations:
9
Fields:
Ana
Anatomy
Translation:
Humans
Animals
Cells
Hecht JT, Montufar-Solis D, Decker G,
Lawler J
, Daniels K, Duke PJ. Retention of cartilage oligomeric matrix protein (COMP) and cell death in redifferentiated pseudoachondroplasia chondrocytes. Matrix Biol. 1998 Dec; 17(8-9):625-33.
PMID:
9923655
.
Citations:
41
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Cells
Adams JC,
Seed B
,
Lawler J
. Muskelin, a novel intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin-1. EMBO J. 1998 Sep 01; 17(17):4964-74.
PMID:
9724633
; PMCID:
PMC1170825
.
Citations:
36
Fields:
Bio
Biotechnology
Mol
Molecular Biology
Translation:
Animals
Cells
Magnetto S, Bruno-Bossio G, Voland C, Lecerf J,
Lawler J
, Delmas P, Silverstein R, Clezardin P. CD36 mediates binding of soluble thrombospondin-1 but not cell adhesion and haptotaxis on immobilized thrombospondin-1. Cell Biochem Funct. 1998 Sep; 16(3):211-21.
PMID:
9747513
.
Citations:
6
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Animals
Cells
Hecht JT, Deere M, Putnam E, Cole W, Vertel B, Chen H,
Lawler J
. Characterization of cartilage oligomeric matrix protein (COMP) in human normal and pseudoachondroplasia musculoskeletal tissues. Matrix Biol. 1998 Aug; 17(4):269-78.
PMID:
9749943
.
Citations:
41
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Cells
Guo N, Zabrenetzky VS, Chandrasekaran L, Sipes JM,
Lawler J
, Krutzsch HC, Roberts DD. Differential roles of protein kinase C and pertussis toxin-sensitive G-binding proteins in modulation of melanoma cell proliferation and motility by thrombospondin 1. Cancer Res. 1998 Jul 15; 58(14):3154-62.
PMID:
9679984
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Crawford SE, Stellmach V, Murphy-Ullrich JE, Ribeiro SM,
Lawler J
, Hynes RO, Boivin GP, Bouck N. Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell. 1998 Jun 26; 93(7):1159-70.
PMID:
9657149
.
Citations:
415
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Volpert OV,
Lawler J
, Bouck NP. A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1. Proc Natl Acad Sci U S A. 1998 May 26; 95(11):6343-8.
PMID:
9600967
; PMCID:
PMC27689
.
Citations:
48
Fields:
Sci
Science
Translation:
Humans
Animals
Urry LA, Whittaker CA, Duquette M,
Lawler J
, DeSimone DW. Thrombospondins in early Xenopus embryos: dynamic patterns of expression suggest diverse roles in nervous system, notochord, and muscle development. Dev Dyn. 1998 Apr; 211(4):390-407.
PMID:
9566958
.
Citations:
9
Fields:
Ana
Anatomy
Translation:
Animals
Cells
Lawler J
, Sunday M, Thibert V, Duquette M, George EL, Rayburn H, Hynes RO. Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. J Clin Invest. 1998 Mar 01; 101(5):982-92.
PMID:
9486968
; PMCID:
PMC508649
.
Citations:
183
Fields:
Med
Medicine (General)
Translation:
Animals
Cells
Riessen R, Kearney M,
Lawler J
, Isner JM. Immunolocalization of thrombospondin-1 in human atherosclerotic and restenotic arteries. Am Heart J. 1998 Feb; 135(2 Pt 1):357-64.
PMID:
9489988
.
Citations:
33
Fields:
Car
Cardiology
Translation:
Humans
Animals
Cells
Merle B, Malaval L,
Lawler J
, Delmas P, Clezardin P. Decorin inhibits cell attachment to thrombospondin-1 by binding to a KKTR-dependent cell adhesive site present within the N-terminal domain of thrombospondin-1. J Cell Biochem. 1997 Oct 01; 67(1):75-83.
PMID:
9328841
.
Citations:
23
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Tucker RP, Hagios C, Chiquet-Ehrismann R,
Lawler J
. In situ localization of thrombospondin-1 and thrombospondin-3 transcripts in the avian embryo. Dev Dyn. 1997 Mar; 208(3):326-37.
PMID:
9056637
.
Citations:
10
Fields:
Ana
Anatomy
Translation:
Animals
Clezardin P,
Lawler J
, Amiral J, Quentin G, Delmas P. Identification of cell adhesive active sites in the N-terminal domain of thrombospondin-1. Biochem J. 1997 Feb 01; 321 ( Pt 3):819-27.
PMID:
9032471
; PMCID:
PMC1218140
.
Citations:
5
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Stellmach V, Volpert OV, Crawford SE,
Lawler J
, Hynes RO, Bouck N. Tumour suppressor genes and angiogenesis: the role of TP53 in fibroblasts. Eur J Cancer. 1996 Dec; 32A(14):2394-400.
PMID:
9059327
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Incardona F,
Lawler J
, Cataldo D, Panet A, Legrand Y, Foidart JM, Legrand C. Heparin-binding domain, type 1 and type 2 repeats of thrombospondin mediate its interaction with human breast cancer cells. J Cell Biochem. 1996 Sep 15; 62(4):431-42.
PMID:
8891889
.
Citations:
6
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Cells
Higazi AA, Upson RH, Cohen RL, Manuppello J, Bognacki J, Henkin J, McCrae KR, Kounnas MZ, Strickland DK, Preissner KT,
Lawler J
, Cines DB. Interaction of single-chain urokinase with its receptor induces the appearance and disappearance of binding epitopes within the resultant complex for other cell surface proteins. Blood. 1996 Jul 15; 88(2):542-51.
PMID:
8695802
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Animals
Cells
Rabhi-Sabile S, Pidard D,
Lawler J
, Renesto P, Chignard M, Legrand C. Proteolysis of thrombospondin during cathepsin-G-induced platelet aggregation: functional role of the 165-kDa carboxy-terminal fragment. FEBS Lett. 1996 May 13; 386(1):82-6.
PMID:
8635609
.
Citations:
11
Fields:
Bio
Biochemistry
Translation:
Humans
Tucker RP, Adams JC,
Lawler J
. Thrombospondin-4 is expressed by early osteogenic tissues in the chick embryo. Dev Dyn. 1995 Aug; 203(4):477-90.
PMID:
7496039
.
Citations:
13
Fields:
Ana
Anatomy
Translation:
Animals
Cells
Qabar A, Derick L,
Lawler J
, Dixit V. Thrombospondin 3 is a pentameric molecule held together by interchain disulfide linkage involving two cysteine residues. J Biol Chem. 1995 May 26; 270(21):12725-9.
PMID:
7759526
.
Citations:
10
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Lawler J
, McHenry K, Duquette M, Derick L. Characterization of human thrombospondin-4. J Biol Chem. 1995 Feb 10; 270(6):2809-14.
PMID:
7852353
.
Citations:
19
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Newton G,
Weremowicz S
,
Morton CC
, Copeland NG, Gilbert DJ, Jenkins NA,
Lawler J
. Characterization of human and mouse cartilage oligomeric matrix protein. Genomics. 1994 Dec; 24(3):435-9.
PMID:
7713493
.
Citations:
37
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Schultz-Cherry S,
Lawler J
, Murphy-Ullrich JE. The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-beta. J Biol Chem. 1994 Oct 28; 269(43):26783-8.
PMID:
7929414
.
Citations:
77
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Luscinskas FW
,
Lawler J
. Integrins as dynamic regulators of vascular function. FASEB J. 1994 Sep; 8(12):929-38.
PMID:
7522194
.
Citations:
56
Fields:
Bio
Biology
Phy
Physiology
Translation:
Humans
Animals
Cells
Adamson GJ, Gellman H, Brumfield RH, Kuschner SH,
Lawler JW
. Flexible implant resection arthroplasty of the proximal interphalangeal joint in patients with systemic inflammatory arthritis. J Hand Surg Am. 1994 May; 19(3):378-84.
PMID:
8056962
.
Citations:
3
Fields:
Gen
General Surgery
Tra
Traumatology
Translation:
Humans
Adams JC,
Lawler J
. Cell-type specific adhesive interactions of skeletal myoblasts with thrombospondin-1. Mol Biol Cell. 1994 Apr; 5(4):423-37.
PMID:
7519904
; PMCID:
PMC301052
.
Citations:
33
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Qabar AN, Lin Z, Wolf FW, O'Shea KS,
Lawler J
, Dixit VM. Thrombospondin 3 is a developmentally regulated heparin binding protein. J Biol Chem. 1994 Jan 14; 269(2):1262-9.
PMID:
8288588
.
Citations:
13
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Ketis NV,
Lawler J
, Bendena WG. Extracellular matrix components affect the pattern of protein synthesis of endothelial cells responding to hyperthermia. In Vitro Cell Dev Biol Anim. 1993 Oct; 29A(10):768-72.
PMID:
8118611
.
Citations:
2
Fields:
Cel
Cell Biology
Zoo
Zoology
Translation:
Humans
Animals
Cells
Lawler J
, Duquette M, Urry L, McHenry K, Smith TF. The evolution of the thrombospondin gene family. J Mol Evol. 1993 Jun; 36(6):509-16.
PMID:
8350346
.
Citations:
13
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
San Antonio JD, Slover J,
Lawler J
, Karnovsky MJ, Lander AD. Specificity in the interactions of extracellular matrix proteins with subpopulations of the glycosaminoglycan heparin. Biochemistry. 1993 May 11; 32(18):4746-55.
PMID:
8490019
.
Citations:
15
Fields:
Bio
Biochemistry
Translation:
Cells
Adams JC,
Lawler J
. Diverse mechanisms for cell attachment to platelet thrombospondin. J Cell Sci. 1993 Apr; 104 ( Pt 4):1061-71.
PMID:
8314891
.
Citations:
18
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Adams J,
Lawler J
. Extracellular matrix: the thrombospondin family. Curr Biol. 1993 Mar; 3(3):188-90.
PMID:
15335796
.
Citations:
24
Fields:
Bio
Biology
Lawler J
, Duquette M, Whittaker CA, Adams JC, McHenry K, DeSimone DW. Identification and characterization of thrombospondin-4, a new member of the thrombospondin gene family. J Cell Biol. 1993 Feb; 120(4):1059-67.
PMID:
8432726
.
Citations:
43
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Legrand C, Thibert V, Dubernard V, Bégault B,
Lawler J
. Molecular requirements for the interaction of thrombospondin with thrombin-activated human platelets: modulation of platelet aggregation. Blood. 1992 Apr 15; 79(8):1995-2003.
PMID:
1562725
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Cells
Corless CL, Mendoza A, Collins T,
Lawler J
. Colocalization of thrombospondin and syndecan during murine development. Dev Dyn. 1992 Apr; 193(4):346-58.
PMID:
1380845
.
Citations:
26
Fields:
Ana
Anatomy
Translation:
Animals
Lawler J
, Ferro P, Duquette M. Expression and mutagenesis of thrombospondin. Biochemistry. 1992 Feb 04; 31(4):1173-80.
PMID:
1734965
.
Citations:
18
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Lawler J
, Duquette M, Ferro P, Copeland NG, Gilbert DJ, Jenkins NA. Characterization of the murine thrombospondin gene. Genomics. 1991 Nov; 11(3):587-600.
PMID:
1774063
.
Citations:
13
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Lawler J
, Duquette M, Ferro P. Cloning and sequencing of chicken thrombospondin. J Biol Chem. 1991 May 05; 266(13):8039-43.
PMID:
2022631
.
Citations:
10
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Coetzer T, Palek J,
Lawler J
, Liu SC,
Jarolim P
, Lahav M, Prchal JT, Wang W, Alter BP, Schewitz G, et al. Structural and functional heterogeneity of alpha spectrin mutations involving the spectrin heterodimer self-association site: relationships to hematologic expression of homozygous hereditary elliptocytosis and hereditary pyropoikilocytosis. Blood. 1990 Jun 01; 75(11):2235-44.
PMID:
2346784
.
Citations:
15
Fields:
Hem
Hematology
Translation:
Humans
Cells
Ketis NV,
Lawler J
. Effects of thrombospondin antibody on the recovery of endothelial cells from hyperthermia. J Cell Sci. 1990 Jun; 96 ( Pt 2):263-70.
PMID:
2211867
.
Citations:
2
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Sherwood JA, Roberts DD, Spitalnik SL,
Lawler JW
, Miller LH, Howard RJ. Falciparum malaria parasitized erythrocytes bind to a carboxy-terminal thrombospondin fragment and not the amino-terminal heparin-binding region. Mol Biochem Parasitol. 1990 May; 40(2):173-81.
PMID:
2194122
.
Citations:
3
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Par
Parasitology
Translation:
Humans
Animals
Cells
Lambert S, Yu H, Prchal JT,
Lawler J
, Ruff P, Speicher D, Cheung MC, Kan YW, Palek J. cDNA sequence for human erythrocyte ankyrin. Proc Natl Acad Sci U S A. 1990 Mar; 87(5):1730-4.
PMID:
1689849
; PMCID:
PMC53556
.
Citations:
44
Fields:
Sci
Science
Translation:
Humans
Cells
Korsgren C,
Lawler J
, Lambert S, Speicher D, Cohen CM. Complete amino acid sequence and homologies of human erythrocyte membrane protein band 4.2. Proc Natl Acad Sci U S A. 1990 Jan; 87(2):613-7.
PMID:
2300550
; PMCID:
PMC53315
.
Citations:
28
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Lawler J
, Hynes RO. An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin. Blood. 1989 Nov 01; 74(6):2022-7.
PMID:
2478219
.
Citations:
49
Fields:
Hem
Hematology
Translation:
Humans
Cells
Jarolim P
, Palek J, Coetzer TL,
Lawler J
, Velez-Garcia E, Fradera J, Charles A, Jacob HS, Moake JL. Severe hemolysis and red cell fragmentation caused by the combination of a spectrin mutation with a thrombotic microangiopathy. Am J Hematol. 1989 Sep; 32(1):50-6.
PMID:
2667341
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
Oquendo P, Hundt E,
Lawler J
,
Seed B
. CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Cell. 1989 Jul 14; 58(1):95-101.
PMID:
2473841
.
Citations:
124
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Lawler J
, Weinstein R, Hynes RO. Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors. J Cell Biol. 1988 Dec; 107(6 Pt 1):2351-61.
PMID:
2848850
; PMCID:
PMC2115659
.
Citations:
113
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Lawler J
, Coetzer TL, Mankad VN, Moore RB, Prchal JT, Palek J. Spectrin-alpha I/61: a new structural variant of alpha-spectrin in a double-heterozygous form of hereditary pyropoikilocytosis. Blood. 1988 Oct; 72(4):1412-5.
PMID:
3167214
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Ketis NV,
Lawler J
, Hoover RL, Karnovsky MJ. Effects of heat shock on the expression of thrombospondin by endothelial cells in culture. J Cell Biol. 1988 Mar; 106(3):893-904.
PMID:
3279055
; PMCID:
PMC2115104
.
Citations:
9
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Dainiak N, Warren HB, Kreczko S, Riordan MA, Feldman L,
Lawler J
, Cohen AM, Davies PF. Acetylated lipoproteins impair erythroid growth factor release from endothelial cells. J Clin Invest. 1988 Mar; 81(3):834-43.
PMID:
3278006
; PMCID:
PMC442534
.
Citations:
2
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Coetzer TL,
Lawler J
, Liu SC, Prchal JT, Gualtieri RJ, Brain MC, Dacie JV, Palek J. Partial ankyrin and spectrin deficiency in severe, atypical hereditary spherocytosis. N Engl J Med. 1988 Jan 28; 318(4):230-4.
PMID:
2961992
.
Citations:
18
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Cohen AM, Liu SC,
Lawler J
, Derick L, Palek J. Identification of the protein 4.1 binding site to phosphatidylserine vesicles. Biochemistry. 1988 Jan 26; 27(2):614-9.
PMID:
3349050
.
Citations:
10
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Coetzer T,
Lawler J
, Prchal JT, Palek J. Molecular determinants of clinical expression of hereditary elliptocytosis and pyropoikilocytosis. Blood. 1987 Sep; 70(3):766-72.
PMID:
3620700
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Cells
Lawler J
, Hynes RO. Structural organization of the thrombospondin molecule. Semin Thromb Hemost. 1987 Jul; 13(3):245-54.
PMID:
3686017
.
Citations:
6
Fields:
Hem
Hematology
Vas
Vascular Diseases
Translation:
Humans
Cells
Clezardin P, Hunter NR,
Lawler J
, Dawes J, McGregor JL. Production, characterization, and use of monoclonal antibodies directed against human blood platelet thrombospondin: immunologic comparison with human endothelial and fibroblast thrombospondins. Semin Thromb Hemost. 1987 Jul; 13(3):261-75.
PMID:
3317839
.
Citations:
2
Fields:
Hem
Hematology
Vas
Vascular Diseases
Translation:
Humans
Cells
Sloand EM, Kenney DM, Chao FC,
Lawler J
, Tullis JL. Platelet antithrombin defect in malignancy: platelet protein alterations. Blood. 1987 Feb; 69(2):479-85.
PMID:
3801664
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
Lawler J
, Hynes RO. The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins. J Cell Biol. 1986 Nov; 103(5):1635-48.
PMID:
2430973
; PMCID:
PMC2114380
.
Citations:
137
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Clezardin P, Hunter NR,
Lawler JW
, Pratt DA, McGregor JL, Pepper DS, Dawes J. Structural and immunological comparison of human thrombospondins isolated from platelets and from culture supernatants of endothelial cells and fibroblasts. Evidence for a thrombospondin polymorphism. Eur J Biochem. 1986 Sep 15; 159(3):569-79.
PMID:
3758079
.
Citations:
4
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Lawler J
. The structural and functional properties of thrombospondin. Blood. 1986 May; 67(5):1197-209.
PMID:
3516249
.
Citations:
69
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Lawler J
, Cohen AM, Chao FC, Moriarty DJ. Thrombospondin in essential thrombocythemia. Blood. 1986 Feb; 67(2):555-8.
PMID:
3510684
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Cells
Lawler J
, Connolly JE, Ferro P, Derick LH. Thrombin and chymotrypsin interactions with thrombospondin. Ann N Y Acad Sci. 1986; 485:273-87.
PMID:
3471148
.
Citations:
16
Fields:
Sci
Science
Translation:
Cells
Dainiak N, Kreczko S, Cohen A, Pannell R,
Lawler J
. Primary human marrow cultures for erythroid bursts in a serum-substituted system. Exp Hematol. 1985 Nov; 13(10):1073-9.
PMID:
4054248
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
Liu SC, Zhai S,
Lawler J
, Palek J. Hemin-mediated dissociation of erythrocyte membrane skeletal proteins. J Biol Chem. 1985 Oct 05; 260(22):12234-9.
PMID:
4044594
.
Citations:
15
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Lawler J
, Coetzer TL, Palek J, Jacob HS, Luban N. Sp alpha I/65: a new variant of the alpha subunit of spectrin in hereditary elliptocytosis. Blood. 1985 Sep; 66(3):706-9.
PMID:
4027386
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Lawler J
, Derick LH, Connolly JE, Chen JH, Chao FC. The structure of human platelet thrombospondin. J Biol Chem. 1985 Mar 25; 260(6):3762-72.
PMID:
2579080
.
Citations:
53
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Lahav J,
Lawler J
,
Gimbrone MA
. Thrombospondin interactions with fibronectin and fibrinogen. Mutual inhibition in binding. Eur J Biochem. 1984 Nov 15; 145(1):151-6.
PMID:
6489349
.
Citations:
22
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Lawler J
, Liu SC, Palek J, Prchal J. A molecular defect of spectrin in a subset of patients with hereditary elliptocytosis. Alterations in the alpha-subunit domain involved in spectrin self-association. J Clin Invest. 1984 Jun; 73(6):1688-95.
PMID:
6725555
; PMCID:
PMC437080
.
Citations:
13
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Lawler J
, Liu SC, Street A, Palek J. Abnormalities in spectrin structure and function in hereditary pyropoikilocytosis and hereditary elliptocytosis. Prog Clin Biol Res. 1984; 159:191-204.
PMID:
6473460
.
Citations:
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Cells
Lawler J
, Palek J, Liu SC, Prchal J, Butler WM. Molecular heterogeneity of hereditary pyropoikilocytosis: identification of a second variant of the spectrin alpha-subunit. Blood. 1983 Dec; 62(6):1182-9.
PMID:
6640107
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Cells
Lawler J
, Simons ER. Cooperative binding of calcium to thrombospondin. The effect of calcium on the circular dichroism and limited tryptic digestion of thrombospondin. J Biol Chem. 1983 Oct 25; 258(20):12098-101.
PMID:
6630182
.
Citations:
22
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Dainiak N, Davies G, Kalmanti M,
Lawler J
, Kulkarni V. Platelet-derived growth factor promotes proliferation of erythropoietic progenitor cells in vitro. J Clin Invest. 1983 May; 71(5):1206-14.
PMID:
6853708
; PMCID:
PMC436980
.
Citations:
16
Fields:
Med
Medicine (General)
Translation:
Humans