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Ala Nozari, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Niu F, Sharma A, Feng L, Ozkizilcik A, Muresanu DF, Lafuente JV, Tian ZR, Nozari A, Sharma HS. Nanowired delivery of DL-3-n-butylphthalide induces superior neuroprotection in concussive head injury. Prog Brain Res. 2019; 245:89-118. PMID: 30961873.
  2. Sharma HS, Muresanu DF, Castellani RJ, Nozari A, Lafuente JV, Tian ZR, Ozkizilcik A, Manzhulo I, Mössler H, Sharma A. Nanowired delivery of cerebrolysin with neprilysin and p-Tau antibodies induces superior neuroprotection in Alzheimer's disease. Prog Brain Res. 2019; 245:145-200. PMID: 30961867.
  3. Ozkizilcik A, Sharma A, Lafuente JV, Muresanu DF, Castellani RJ, Nozari A, Tian ZR, Mössler H, Sharma HS. Nanodelivery of cerebrolysin reduces pathophysiology of Parkinson's disease. Prog Brain Res. 2019; 245:201-246. PMID: 30961868.
  4. Nozari A, Akeju O, Mirzakhani H, Eskandar E, Ma Z, Hossain MA, Wang Q, Greenblatt DJ, Martyn JAJ. Prolonged therapy with the anticonvulsant carbamazepine leads to increased plasma clearance of fentanyl. J Pharm Pharmacol. 2019 Jun; 71(6):982-987. PMID: 30793320.
  5. Sabouri AS, Crawford L, Bick SK, Nozari A, Anderson TA. Is a Retrolaminar Approach to the Thoracic Paravertebral Space Possible?: A Human Cadaveric Study. Reg Anesth Pain Med. 2018 Nov; 43(8):864-868. PMID: 29923954.
    Citations:    Fields:    Translation:Humans
  6. Patnaik R, Sharma A, Skaper SD, Muresanu DF, Lafuente JV, Castellani RJ, Nozari A, Sharma HS. Histamine H3 Inverse Agonist BF 2649 or Antagonist with Partial H4 Agonist Activity Clobenpropit Reduces Amyloid Beta Peptide-Induced Brain Pathology in Alzheimer's Disease. Mol Neurobiol. 2018 01; 55(1):312-321. PMID: 28861757.
    Citations: 1     Fields:    
  7. Motayagheni N, Phan S, Eshraghi C, Nozari A, Atala A. A Review of Anesthetic Effects on Renal Function: Potential Organ Protection. Am J Nephrol. 2017; 46(5):380-389. PMID: 29131005.
    Citations:    Fields:    Translation:Humans
  8. Sharma HS, Patnaik R, Muresanu DF, Lafuente JV, Ozkizilcik A, Tian ZR, Nozari A, Sharma A. Histaminergic Receptors Modulate Spinal Cord Injury-Induced Neuronal Nitric Oxide Synthase Upregulation and Cord Pathology: New Roles of Nanowired Drug Delivery for Neuroprotection. Int Rev Neurobiol. 2017; 137:65-98. PMID: 29132544.
    Citations:    Fields:    Translation:HumansAnimalsCells
  9. Mirzakhani H, Eikermann M, Bittner E, Nozari A. In Response. Anesth Analg. 2017 04; 124(4):1371-1372. PMID: 28319553.
    Citations:    Fields:    
  10. Mirzakhani H, Eikermann M, Bittner E, Nozari A. In Response: Effective Doses of Neuromuscular Blockers During Electroconvulsive Therapy and the Effect of ECT Parameters. Anesth Analg. 2017 Feb 16. PMID: 28212216.
    Citations:    Fields:    
  11. Timm FP, Houle TT, Grabitz SD, Lihn AL, Stokholm JB, Eikermann-Haerter K, Nozari A, Kurth T, Eikermann M. Migraine and risk of perioperative ischemic stroke and hospital readmission: hospital based registry study. BMJ. 2017 Jan 10; 356:i6635. PMID: 28073753.
    Citations: 6     Fields:    Translation:Humans
  12. Motayagheni N, Phan S, Nozari A, Atala A. Lipid Emulsion, More Than Reversing Bupivacaine Cardiotoxicity: Potential Organ Protection. J Pharm Pharm Sci. 2017; 20(1):329-331. PMID: 29145932.
    Citations:    Fields:    Translation:HumansAnimalsCells
  13. Mirzakhani H, Nozari A. In Response. Anesth Analg. 2016 11; 123(5):1329-1330. PMID: 27551738.
    Citations:    Fields:    
  14. Mirzakhani H, Bittner E, Eikermann M, Nozari A. In Response. Anesth Analg. 2016 10; 123(4):1060-1. PMID: 27636580.
    Citations:    Fields:    
  15. Mirzakhani H, Guchelaar HJ, Welch CA, Cusin C, Doran ME, MacDonald TO, Bittner EA, Eikermann M, Nozari A. Minimum Effective Doses of Succinylcholine and Rocuronium During Electroconvulsive Therapy: A Prospective, Randomized, Crossover Trial. Anesth Analg. 2016 09; 123(3):587-96. PMID: 26967896.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  16. Sharma HS, Muresanu DF, Lafuente JV, Nozari A, Patnaik R, Skaper SD, Sharma A. Pathophysiology of Blood-Brain Barrier in Brain Injury in Cold and Hot Environments: Novel Drug Targets for Neuroprotection. CNS Neurol Disord Drug Targets. 2016; 15(9):1045-1071. PMID: 27592625.
    Citations: 3     Fields:    Translation:HumansAnimals
  17. Oka F, Hoffmann U, Lee JH, Shin HK, Chung DY, Yuzawa I, Chen SP, Atalay YB, Nozari A, Hopson KP, Qin T, Ayata C. Requisite ischemia for spreading depolarization occurrence after subarachnoid hemorrhage in rodents. J Cereb Blood Flow Metab. 2017 May; 37(5):1829-1840. PMID: 27432225.
    Citations: 4     Fields:    Translation:Animals
  18. Goverman J, Bittner EA, Friedstat JS, Moore M, Nozari A, Ibrahim AE, Sarhane KA, Chang PH, Sheridan RL, Fagan SP. Discrepancy in Initial Pediatric Burn Estimates and Its Impact on Fluid Resuscitation. J Burn Care Res. 2015 Sep-Oct; 36(5):574-9. PMID: 25407387.
    Citations: 4     Fields:    Translation:Humans
  19. Mirzakhani H, van Noorden MS, Swen J, Nozari A, Guchelaar HJ. Pharmacogenetics in electroconvulsive therapy and adjunctive medications. Pharmacogenomics. 2015; 16(9):1015-31. PMID: 26115083.
    Citations:    Fields:    Translation:Humans
  20. Barnett SR, Nozari A. The preoperative evaluation of the neurosurgical patient. Int Anesthesiol Clin. 2015; 53(1):1-22. PMID: 25551739.
    Citations:    Fields:    Translation:Humans
  21. Wiener-Kronish J, Nozari A. Blood transfusions and infected lungs--worse outcomes?*. Crit Care Med. 2014 Jul; 42(7):1739-40. PMID: 24933055.
    Citations:    Fields:    Translation:Humans
  22. Mirzakhani H, Nozari A, Ehrenfeld JM, Peterfreund R, Szabo M, Walsh JL, Jiang Y, Sandberg W, Rosow C, Wang J. Case report: profound hypotension after anesthetic induction with propofol in patients treated with rifampin. Anesth Analg. 2013 Jul; 117(1):61-4. PMID: 23687230.
    Citations:    Fields:    Translation:Humans
  23. Kida K, Minamishima S, Wang H, Ren J, Yigitkanli K, Nozari A, Mandeville JB, Liu PK, Liu CH, Ichinose F. Sodium sulfide prevents water diffusion abnormality in the brain and improves long term outcome after cardiac arrest in mice. Resuscitation. 2012 Oct; 83(10):1292-7. PMID: 22370005.
    Citations: 14     Fields:    Translation:AnimalsCells
  24. Simon MV, Cole AJ, Chang EC, Buchbinder BR, Stufflebeam SM, Nozari A, Stemmer-Rachamimov AO, Eskandar EN. An intraoperative multimodal neurophysiologic approach to successful resection of precentral gyrus epileptogenic lesions. Epilepsia. 2012 Apr; 53(4):e75-9. PMID: 22309192.
    Citations: 2     Fields:    Translation:Humans
  25. Tian ZR, Sharma A, Nozari A, Subramaniam R, Lundstedt T, Sharma HS. Nanowired drug delivery to enhance neuroprotection in spinal cord injury. CNS Neurol Disord Drug Targets. 2012 Feb; 11(1):86-95. PMID: 22385571.
    Citations: 10     Fields:    Translation:HumansAnimals
  26. Mirzakhani H, Welch CA, Eikermann M, Nozari A. Neuromuscular blocking agents for electroconvulsive therapy: a systematic review. Acta Anaesthesiol Scand. 2012 Jan; 56(1):3-16. PMID: 22092267.
    Citations: 7     Fields:    Translation:Humans
  27. Semenas E, Sharma HS, Nozari A, Basu S, Wiklund L. Neuroprotective effects of 17ß-estradiol after hypovolemic cardiac arrest in immature piglets: the role of nitric oxide and peroxidation. Shock. 2011 Jul; 36(1):30-7. PMID: 21330940.
    Citations: 1     Fields:    Translation:AnimalsCells
  28. Semenas E, Nozari A, Thiblin I, Rubertsson S, Wiklund L. Modulation of nitric oxide expression with methylene blue does not improve outcome after hypovolemic cardiac arrest. Resuscitation. 2011 Oct; 82(10):1344-9. PMID: 21636201.
    Citations:    Fields:    Translation:Animals
  29. Semenas E, Nozari A, Wiklund L. Sex differences in cardiac injury after severe haemorrhage and ventricular fibrillation in pigs. Resuscitation. 2010 Dec; 81(12):1718-22. PMID: 20817375.
    Citations:    Fields:    Translation:Animals
  30. Dalkara T, Nozari A, Moskowitz MA. Migraine aura pathophysiology: the role of blood vessels and microembolisation. Lancet Neurol. 2010 Mar; 9(3):309-17. PMID: 20170844.
    Citations: 27     Fields:    Translation:HumansAnimals
  31. Nozari A, Dilekoz E, Sukhotinsky I, Stein T, Eikermann-Haerter K, Liu C, Wang Y, Frosch MP, Waeber C, Ayata C, Moskowitz MA. Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Ann Neurol. 2010 Feb; 67(2):221-9. PMID: 20225282.
    Citations: 54     Fields:    Translation:Animals
  32. Bethune W, Nozari A. Cerebral aneurysm surgery in a patient with Brugada syndrome: anesthetic implications and perioperative management. J Neurosurg Anesthesiol. 2010 Jan; 22(1):82-3. PMID: 20027013.
    Citations: 1     Fields:    Translation:Humans
  33. Semenas E, Nozari A, Sharma HS, Basu S, Rubertsson S, Wiklund L. Sex differences in cerebral injury after severe haemorrhage and ventricular fibrillation in pigs. Acta Anaesthesiol Scand. 2010 Mar; 54(3):343-53. PMID: 19764903.
    Citations: 2     Fields:    Translation:Animals
  34. Kudo C, Nozari A, Moskowitz MA, Ayata C. The impact of anesthetics and hyperoxia on cortical spreading depression. Exp Neurol. 2008 Jul; 212(1):201-6. PMID: 18501348.
    Citations: 29     Fields:    Translation:Animals
  35. Nozari A, Safar P, Stezoski SW, Wu X, Kostelnik S, Radovsky A, Tisherman S, Kochanek PM. Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation. Circulation. 2006 Jun 13; 113(23):2690-6. PMID: 16769925.
    Citations: 42     Fields:    Translation:Animals
  36. Nozari A, Alston TA. Tuning up the compression and applying the choke for better horsepower in resuscitation. Crit Care Med. 2006 May; 34(5):1563-4. PMID: 16633262.
    Citations:    Fields:    Translation:Humans
  37. Wu X, Kochanek PM, Cochran K, Nozari A, Henchir J, Stezoski SW, Wagner R, Wisniewski S, Tisherman SA. Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs. J Trauma. 2005 Aug; 59(2):291-9; discussion 299-301. PMID: 16294067.
    Citations: 9     Fields:    Translation:Animals
  38. Nozari A, Safar P, Wu X, Stezoski WS, Henchir J, Kochanek P, Klain M, Radovsky A, Tisherman SA. Suspended animation can allow survival without brain damage after traumatic exsanguination cardiac arrest of 60 minutes in dogs. J Trauma. 2004 Dec; 57(6):1266-75. PMID: 15625460.
    Citations: 5     Fields:    Translation:Animals
  39. Nozari A, Safar P, Stezoski SW, Wu X, Henchir J, Radovsky A, Hanson K, Klein E, Kochanek PM, Tisherman SA. Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs. Crit Care Med. 2004 Oct; 32(10):2110-6. PMID: 15483422.
    Citations: 11     Fields:    Translation:Animals
  40. Liu XL, Wiklund L, Nozari A, Rubertsson S, Basu S. Differences in cerebral reperfusion and oxidative injury after cardiac arrest in pigs. Acta Anaesthesiol Scand. 2003 Sep; 47(8):958-67. PMID: 12904187.
    Citations: 6     Fields:    Translation:Animals
  41. Wu X, Stezoski J, Safar P, Nozari A, Tisherman SA. After spontaneous hypothermia during hemorrhagic shock, continuing mild hypothermia (34 degrees C) improves early but not late survival in rats. J Trauma. 2003 Aug; 55(2):308-16. PMID: 12913642.
    Citations: 4     Fields:    Translation:Animals
  42. Basu S, Liu X, Nozari A, Rubertsson S, Miclescu A, Wiklund L. Evidence for time-dependent maximum increase of free radical damage and eicosanoid formation in the brain as related to duration of cardiac arrest and cardio-pulmonary resuscitation. Free Radic Res. 2003 Mar; 37(3):251-6. PMID: 12688420.
    Citations: 8     Fields:    Translation:Animals
  43. Liu X, Nozari A, Rubertsson S, Wiklund L. Buffer administration during CPR promotes cerebral reperfusion after return of spontaneous circulation and mitigates post-resuscitation cerebral acidosis. Resuscitation. 2002 Oct; 55(1):45-55. PMID: 12297353.
    Citations: 1     Fields:    Translation:Animals
  44. Behringer W, Safar P, Wu X, Nozari A, Abdullah A, Stezoski SW, Tisherman SA. Veno-venous extracorporeal blood shunt cooling to induce mild hypothermia in dog experiments and review of cooling methods. Resuscitation. 2002 Jul; 54(1):89-98. PMID: 12104113.
    Citations: 2     Fields:    Translation:HumansAnimals
  45. Liu XL, Nozari A, Basu S, Ronquist G, Rubertsson S, Wiklund L. Neurological outcome after experimental cardiopulmonary resuscitation: a result of delayed and potentially treatable neuronal injury? Acta Anaesthesiol Scand. 2002 May; 46(5):537-46. PMID: 12027848.
    Citations: 3     Fields:    Translation:Animals
  46. Nozari A, Rubertsson S, Wiklund L. Differences in the pharmacodynamics of epinephrine and vasopressin during and after experimental cardiopulmonary resuscitation. Resuscitation. 2001 Apr; 49(1):59-72. PMID: 11334693.
    Citations: 1     Fields:    Translation:Animals
  47. Wiklund L, Nozari A, Rubertsson S. On the existence of dragons. Resuscitation. 2001 Feb; 48(2):187-8. PMID: 11426482.
    Citations:    Fields:    Translation:Animals
  48. Nozari A, Rubertsson S, Wiklund L. Improved cerebral blood supply and oxygenation by aortic balloon occlusion combined with intra-aortic vasopressin administration during experimental cardiopulmonary resuscitation. Acta Anaesthesiol Scand. 2000 Nov; 44(10):1209-19. PMID: 11065200.
    Citations: 1     Fields:    Translation:Animals
  49. Nozari A, Rubertsson S, Wiklund L. Intra-aortic administration of epinephrine above an aortic balloon occlusion during experimental CPR does not further improve cerebral blood flow and oxygenation. Resuscitation. 2000 Apr; 44(2):119-27. PMID: 10767499.
    Citations: 1     Fields:    Translation:Animals
  50. Basu S, Nozari A, Liu XL, Rubertsson S, Wiklund L. Development of a novel biomarker of free radical damage in reperfusion injury after cardiac arrest. FEBS Lett. 2000 Mar 17; 470(1):1-6. PMID: 10722834.
    Citations: 12     Fields:    Translation:AnimalsCells
  51. Nozari A, Rubertsson S, Gedeborg R, Nordgren A, Wiklund L. Maximisation of cerebral blood flow during experimental cardiopulmonary resuscitation does not ameliorate post-resuscitation hypoperfusion. Resuscitation. 1999 Jan; 40(1):27-35. PMID: 10321845.
    Citations: 2     Fields:    Translation:Animals
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.