Harvard Catalyst Profiles

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Roger Keith Pitman, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01MH068603 (PITMAN, ROGER K.) Aug 1, 2004 - May 31, 2009
    Prophylaxis of PTSD with Post-Trauma Propranolol
    Role: Principal Investigator
  2. R01MH058671 (PITMAN, ROGER K.) Sep 1, 1998 - May 31, 2002
    Role: Principal Investigator
  3. M01RR001066 (SLAVIN, PETER L) Jan 6, 1997 - Nov 30, 2007
    General Clinical Research Center
    Role: Co-Principal Investigator
  4. R01MH054636 (SHIN, LISA M) Sep 30, 1995 - Oct 31, 2014
    Twin Study of Biologic Markers for PTSD
    Role: Co-Principal Investigator
  5. R03TW000452 (PITMAN, ROGER K.) Sep 1, 1994 - Aug 31, 1998
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Thiel F, Berman Z, Dishy GA, Chan SJ, Seth H, Tokala M, Pitman RK, Dekel S. Traumatic memories of childbirth relate to maternal postpartum posttraumatic stress disorder. J Anxiety Disord. 2021 Jan; 77:102342. PMID: 33276245.
    Citations:    Fields:    
  2. Osborne MT, Shin LM, Mehta NN, Pitman RK, Fayad ZA, Tawakol A. Disentangling the Links Between Psychosocial Stress and Cardiovascular Disease. Circ Cardiovasc Imaging. 2020 08; 13(8):e010931. PMID: 32791843.
    Citations:    Fields:    
  3. Dar T, Osborne MT, Abohashem S, Abbasi T, Choi KW, Ghoneem A, Naddaf N, Smoller JW, Pitman RK, Denninger JW, Shin LM, Fricchione G, Tawakol A. Greater Neurobiological Resilience to Chronic Socioeconomic or Environmental Stressors Associates With Lower Risk for Cardiovascular Disease Events. Circ Cardiovasc Imaging. 2020 08; 13(8):e010337. PMID: 32787499.
    Citations:    Fields:    
  4. Osborne MT, Radfar A, Hassan MZO, Abohashem S, Oberfeld B, Patrich T, Tung B, Wang Y, Ishai A, Scott JA, Shin LM, Fayad ZA, Koenen KC, Rajagopalan S, Pitman RK, Tawakol A. A neurobiological mechanism linking transportation noise to cardiovascular disease in humans. Eur Heart J. 2020 02 01; 41(6):772-782. PMID: 31769799.
    Citations: 10     Fields:    
  5. Tanev KS, Federico LE, Greenberg MS, Orr SP, Goetter EM, Resick PA, Pitman RK. Baseline Cognitive Performance and Treatment Outcomes From Cognitive-Behavioral Therapies for Posttraumatic Stress Disorder: A Naturalistic Study. J Neuropsychiatry Clin Neurosci. 2020; 32(3):286-293. PMID: 31948321.
    Citations:    Fields:    
  6. Tawakol A, Osborne MT, Wang Y, Hammed B, Tung B, Patrich T, Oberfeld B, Ishai A, Shin LM, Nahrendorf M, Warner ET, Wasfy J, Fayad ZA, Koenen K, Ridker PM, Pitman RK, Armstrong KA. Stress-Associated Neurobiological Pathway Linking Socioeconomic Disparities to Cardiovascular Disease. J Am Coll Cardiol. 2019 07 02; 73(25):3243-3255. PMID: 31248544.
    Citations: 17     Fields:    Translation:Humans
  7. Dekel S, Ein-Dor T, Berman Z, Barsoumian IS, Agarwal S, Pitman RK. Delivery mode is associated with maternal mental health following childbirth. Arch Womens Ment Health. 2019 12; 22(6):817-824. PMID: 31041603.
    Citations: 3     Fields:    Translation:Humans
  8. Dar T, Radfar A, Abohashem S, Pitman RK, Tawakol A, Osborne MT. Psychosocial Stress and Cardiovascular Disease. Curr Treat Options Cardiovasc Med. 2019 Apr 26; 21(5):23. PMID: 31028483.
    Citations: 8     
  9. Ishai A, Osborne MT, Tung B, Wang Y, Hammad B, Patrich T, Oberfeld B, Fayad ZA, Giles JT, Lo J, Shin LM, Grinspoon SK, Koenen KC, Pitman RK, Tawakol A. Amygdalar Metabolic Activity Independently Associates With Progression of Visceral Adiposity. J Clin Endocrinol Metab. 2019 04 01; 104(4):1029-1038. PMID: 30383236.
    Citations: 2     Fields:    Translation:Humans
  10. Goyal A, Dey AK, Chaturvedi A, Elnabawi YA, Aberra TM, Chung JH, Belur AD, Groenendyk JW, Lerman JB, Rivers JP, Rodante JA, Harrington CL, Varghese NJ, Sanda GE, Baumer Y, Sorokin AV, Teague HL, Genovese LD, Natarajan B, Joshi AA, Playford MP, Bluemke DA, Chen MY, Alavi A, Pitman RK, Powell-Wiley TM, Tawakol A, Gelfand JM, Mehta NN. Chronic Stress-Related Neural Activity Associates With Subclinical Cardiovascular Disease in Psoriasis: A Prospective Cohort Study. JACC Cardiovasc Imaging. 2020 02; 13(2 Pt 1):465-477. PMID: 30448131.
    Citations: 9     Fields:    Translation:Humans
  11. Brunet A, Saumier D, Pitman RK. On the Use of Memory Update Mechanisms to Treat Patients: Response to Waits and Hoge. Am J Psychiatry. 2018 11 01; 175(11):1145-1146. PMID: 30380937.
    Citations: 1     Fields:    Translation:Humans
  12. Osborne MT, Ishai A, Hammad B, Tung B, Wang Y, Baruch A, Fayad ZA, Giles JT, Lo J, Shin LM, Grinspoon SK, Koenen KC, Pitman RK, Tawakol A. Amygdalar activity predicts future incident diabetes independently of adiposity. Psychoneuroendocrinology. 2019 02; 100:32-40. PMID: 30273797.
    Citations: 7     Fields:    Translation:Humans
  13. Brunet A, Saumier D, Liu A, Streiner DL, Tremblay J, Pitman RK. Reduction of PTSD Symptoms With Pre-Reactivation Propranolol Therapy: A Randomized Controlled Trial. Am J Psychiatry. 2018 05 01; 175(5):427-433. PMID: 29325446.
    Citations: 23     Fields:    Translation:Humans
  14. Dahlgren MK, Laifer LM, VanElzakker MB, Offringa R, Hughes KC, Staples-Bradley LK, Dubois SJ, Lasko NB, Hinojosa CA, Orr SP, Pitman RK, Shin LM. Diminished medial prefrontal cortex activation during the recollection of stressful events is an acquired characteristic of PTSD. Psychol Med. 2018 05; 48(7):1128-1138. PMID: 28893331.
    Citations: 6     Fields:    Translation:Humans
  15. Tanev KS, Orr SP, Pace-Schott EF, Griffin M, Pitman RK, Resick PA. Positive Association Between Nightmares and Heart Rate Response to Loud Tones: Relationship to Parasympathetic Dysfunction in PTSD Nightmares. J Nerv Ment Dis. 2017 04; 205(4):308-312. PMID: 28129305.
    Citations: 3     Fields:    Translation:Humans
  16. Tanev KS, Winokur A, Pitman RK. Sleep Patterns and Neuropsychiatric Symptoms in Hospitalized Patients With Dementia. J Neuropsychiatry Clin Neurosci. 2017; 29(3):248-253. PMID: 28294708.
    Citations: 2     Fields:    Translation:Humans
  17. Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y, Truong QA, Solomon CJ, Calcagno C, Mani V, Tang CY, Mulder WJ, Murrough JW, Hoffmann U, Nahrendorf M, Shin LM, Fayad ZA, Pitman RK. Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study. Lancet. 2017 02 25; 389(10071):834-845. PMID: 28088338.
    Citations: 92     Fields:    Translation:Humans
  18. Thomas É, Saumier D, Pitman RK, Tremblay J, Brunet A. Consolidation and reconsolidation are impaired by oral propranolol administered before but not after memory (re)activation in humans. Neurobiol Learn Mem. 2017 Jul; 142(Pt A):118-125. PMID: 28003127.
    Citations: 4     Fields:    Translation:Humans
  19. Fricchione J, Greenberg MS, Spring J, Wood N, Mueller-Pfeiffer C, Milad MR, Pitman RK, Orr SP. Delayed extinction fails to reduce skin conductance reactivity to fear-conditioned stimuli. Psychophysiology. 2016 09; 53(9):1343-51. PMID: 27314560.
    Citations: 5     Fields:    Translation:Humans
  20. Pitman RK. Harnessing Reconsolidation to Treat Mental Disorders. Biol Psychiatry. 2015 Dec 15; 78(12):819-20. PMID: 26589491.
    Citations: 3     Fields:    Translation:Humans
  21. Rosenbaum BL, Bui E, Marin MF, Holt DJ, Lasko NB, Pitman RK, Orr SP, Milad MR. Reprint of: "Demographic factors predict magnitude of conditioned fear". Int J Psychophysiol. 2015 Dec; 98(3 Pt 2):606-11. PMID: 26608179.
    Citations:    Fields:    
  22. Goetz JM, Pitman SR, Tanev KS, Pitman RK, Chemtob CM. Mixed-Handedness in Identical Twins Discordant for Combat Exposure in Vietnam: Relationship to Posttraumatic Stress Disorder. J Neuropsychiatry Clin Neurosci. 2016; 28(1):45-8. PMID: 26404173.
    Citations:    Fields:    Translation:Humans
  23. Rosenbaum BL, Bui E, Marin MF, Holt DJ, Lasko NB, Pitman RK, Orr SP, Milad MR. Demographic factors predict magnitude of conditioned fear. Int J Psychophysiol. 2015 Oct; 98(1):59-64. PMID: 26151498.
    Citations: 6     Fields:    Translation:Humans
  24. Pachas GN, Gilman J, Orr SP, Hoeppner B, Carlini SV, Grasser EB, Loebl T, Nino J, Pitman RK, Evins AE. Erratum to: Single dose propranolol does not affect physiologic or emotional reactivity to smoking cues. Psychopharmacology (Berl). 2015 Jun; 232(11):2029. PMID: 25877745.
    Citations: 1     Fields:    
  25. Greenberg MS, Wood NE, Spring JD, Gurvits TV, Nagurney JT, Zafonte RD, Pitman RK. Pilot Study of Neurological Soft Signs and Depressive and Postconcussive Symptoms During Recovery From Mild Traumatic Brain Injury (mTBI). J Neuropsychiatry Clin Neurosci. 2015; 27(3):199-205. PMID: 26222967.
    Citations:    Fields:    Translation:Humans
  26. Pachas GN, Gilman J, Orr SP, Hoeppner B, Carlini SV, Grasser EB, Loebl T, Nino J, Pitman RK, Evins AE. Single dose propranolol does not affect physiologic or emotional reactivity to smoking cues. Psychopharmacology (Berl). 2015 May; 232(9):1619-28. PMID: 25413896.
    Citations: 15     Fields:    Translation:Humans
  27. Wood NE, Rosasco ML, Suris AM, Spring JD, Marin MF, Lasko NB, Goetz JM, Fischer AM, Orr SP, Pitman RK. Pharmacological blockade of memory reconsolidation in posttraumatic stress disorder: three negative psychophysiological studies. Psychiatry Res. 2015 Jan 30; 225(1-2):31-39. PMID: 25441015.
    Citations: 50     Fields:    Translation:Humans
  28. Spring JD, Wood NE, Mueller-Pfeiffer C, Milad MR, Pitman RK, Orr SP. Prereactivation propranolol fails to reduce skin conductance reactivity to prepared fear-conditioned stimuli. Psychophysiology. 2015 Mar; 52(3):407-15. PMID: 25224026.
    Citations: 17     Fields:    Translation:Humans
  29. Greenberg MS, Tanev K, Marin MF, Pitman RK. Stress, PTSD, and dementia. Alzheimers Dement. 2014 Jun; 10(3 Suppl):S155-65. PMID: 24924667.
    Citations: 33     Fields:    Translation:HumansAnimals
  30. Brunet A, Thomas É, Saumier D, Ashbaugh AR, Azzoug A, Pitman RK, Orr SP, Tremblay J. Trauma reactivation plus propranolol is associated with durably low physiological responding during subsequent script-driven traumatic imagery. Can J Psychiatry. 2014 Apr; 59(4):228-32. PMID: 25007116.
    Citations: 18     Fields:    Translation:Humans
  31. Pace-Schott EF, Tracy LE, Rubin Z, Mollica AG, Ellenbogen JM, Bianchi MT, Milad MR, Pitman RK, Orr SP. Interactions of time of day and sleep with between-session habituation and extinction memory in young adult males. Exp Brain Res. 2014 May; 232(5):1443-58. PMID: 24481663.
    Citations: 6     Fields:    Translation:Humans
  32. Bhuvaneswar CG, Ruskin JN, Katzman AR, Wood N, Pitman RK. Pilot study of the effect of lipophilic vs. hydrophilic beta-adrenergic blockers being taken at time of intracardiac defibrillator discharge on subsequent PTSD symptoms. Neurobiol Learn Mem. 2014 Jul; 112:248-52. PMID: 24389538.
    Citations: 4     Fields:    Translation:Humans
  33. Mueller-Pfeiffer C, Zeffiro T, O'Gorman R, Michels L, Baumann P, Wood N, Spring J, Rufer M, Pitman RK, Orr SP. Cortical and cerebellar modulation of autonomic responses to loud sounds. Psychophysiology. 2014 Jan; 51(1):60-9. PMID: 24016238.
    Citations: 5     Fields:    Translation:Humans
  34. Pace-Schott EF, Spencer RM, Vijayakumar S, Ahmed NA, Verga PW, Orr SP, Pitman RK, Milad MR. Extinction of conditioned fear is better learned and recalled in the morning than in the evening. J Psychiatr Res. 2013 Nov; 47(11):1776-84. PMID: 23992769.
    Citations: 25     Fields:    Translation:Humans
  35. Pineles SL, Suvak MK, Liverant GI, Gregor K, Wisco BE, Pitman RK, Orr SP. Psychophysiologic reactivity, subjective distress, and their associations with PTSD diagnosis. J Abnorm Psychol. 2013 Aug; 122(3):635-44. PMID: 24016006.
    Citations: 7     Fields:    Translation:Humans
  36. Lonergan MH, Olivera-Figueroa LA, Pitman RK, Brunet A. Propranolol's effects on the consolidation and reconsolidation of long-term emotional memory in healthy participants: a meta-analysis. J Psychiatry Neurosci. 2013 Jul; 38(4):222-31. PMID: 23182304.
    Citations: 52     Fields:    Translation:Humans
  37. Weiner MW, Friedl KE, Pacifico A, Chapman JC, Jaffee MS, Little DM, Manley GT, McKee A, Petersen RC, Pitman RK, Yaffe K, Zetterberg H, Obana R, Bain LJ, Carrillo MC. Military risk factors for Alzheimer's disease. Alzheimers Dement. 2013 Jul; 9(4):445-51. PMID: 23809365.
    Citations: 22     Fields:    Translation:Humans
  38. Elman I, Gurvits TV, Tschibelu E, Spring JD, Lasko NB, Pitman RK. Neurological soft signs in individuals with pathological gambling. PLoS One. 2013; 8(4):e60885. PMID: 23593341.
    Citations: 2     Fields:    Translation:Humans
  39. Delahanty DL, Gabert-Quillen C, Ostrowski SA, Nugent NR, Fischer B, Morris A, Pitman RK, Bon J, Fallon W. The efficacy of initial hydrocortisone administration at preventing posttraumatic distress in adult trauma patients: a randomized trial. CNS Spectr. 2013 Apr; 18(2):103-11. PMID: 23557627.
    Citations: 25     Fields:    Translation:Humans
  40. Li Y, Meloni EG, Carlezon WA, Milad MR, Pitman RK, Nader K, Bolshakov VY. Learning and reconsolidation implicate different synaptic mechanisms. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4798-803. PMID: 23487762.
    Citations: 20     Fields:    Translation:AnimalsCells
  41. Hall T, Galletly C, Clark CR, Veltmeyer M, Metzger LJ, Gilbertson MW, Orr SP, Pitman RK, McFarlane A. The relationship between Hippocampal asymmetry and working memory processing in combat-related PTSD - a monozygotic twin study. Biol Mood Anxiety Disord. 2012 Dec 01; 2:21. PMID: 23198722.
    Citations: 3     
  42. Pitman RK, Rasmusson AM, Koenen KC, Shin LM, Orr SP, Gilbertson MW, Milad MR, Liberzon I. Biological studies of post-traumatic stress disorder. Nat Rev Neurosci. 2012 Nov; 13(11):769-87. PMID: 23047775.
    Citations: 373     Fields:    Translation:HumansAnimals
  43. Gamache K, Pitman RK, Nader K. Preclinical evaluation of reconsolidation blockade by clonidine as a potential novel treatment for posttraumatic stress disorder. Neuropsychopharmacology. 2012 Dec; 37(13):2789-96. PMID: 22871915.
    Citations: 22     Fields:    Translation:Animals
  44. Hoexter MQ, Fadel G, Felício AC, Calzavara MB, Batista IR, Reis MA, Shih MC, Pitman RK, Andreoli SB, Mello MF, Mari JJ, Bressan RA. Higher striatal dopamine transporter density in PTSD: an in vivo SPECT study with [(99m)Tc]TRODAT-1. Psychopharmacology (Berl). 2012 Nov; 224(2):337-45. PMID: 22700036.
    Citations: 26     Fields:    Translation:Humans
  45. Orr SP, Lasko NB, Macklin ML, Pineles SL, Chang Y, Pitman RK. Predicting post-trauma stress symptoms from pre-trauma psychophysiologic reactivity, personality traits and measures of psychopathology. Biol Mood Anxiety Disord. 2012 May 18; 2:8. PMID: 22738068.
    Citations: 18     
  46. Pineles SL, Rasmusson AM, Yehuda R, Lasko NB, Macklin ML, Pitman RK, Orr SP. Predicting emotional responses to potentially traumatic events from pre-exposure waking cortisol levels: a longitudinal study of police and firefighters. Anxiety Stress Coping. 2013; 26(3):241-53. PMID: 22574657.
    Citations: 7     Fields:    Translation:Humans
  47. Mueller-Pfeiffer C, Rufibach K, Perron N, Wyss D, Kuenzler C, Prezewowsky C, Pitman RK, Rufer M. Global functioning and disability in dissociative disorders. Psychiatry Res. 2012 Dec 30; 200(2-3):475-81. PMID: 22578820.
    Citations: 9     Fields:    Translation:Humans
  48. Linnman C, Zeidan MA, Furtak SC, Pitman RK, Quirk GJ, Milad MR. Resting amygdala and medial prefrontal metabolism predicts functional activation of the fear extinction circuit. Am J Psychiatry. 2012 Apr; 169(4):415-23. PMID: 22318762.
    Citations: 46     Fields:    Translation:Humans
  49. Linnman C, Zeidan MA, Pitman RK, Milad MR. Reprint of: resting cerebral metabolism correlates with skin conductance and functional brain activation during fear conditioning. Biol Psychol. 2013 01; 92(1):26-35. PMID: 22425559.
    Citations: 1     Fields:    
  50. Linnman C, Zeidan MA, Pitman RK, Milad MR. Resting cerebral metabolism correlates with skin conductance and functional brain activation during fear conditioning. Biol Psychol. 2012 Feb; 89(2):450-9. PMID: 22207247.
    Citations: 16     Fields:    Translation:Humans
  51. Linnman C, Zeffiro TA, Pitman RK, Milad MR. An fMRI study of unconditioned responses in post-traumatic stress disorder. Biol Mood Anxiety Disord. 2011 Nov 01; 1(1):8. PMID: 22738227.
    Citations: 30     
  52. Brunet A, Ashbaugh AR, Saumier D, Nelson M, Pitman RK, Tremblay J, Roullet P, Birmes P. Does reconsolidation occur in humans: a reply. Front Behav Neurosci. 2011; 5:74. PMID: 22065414.
    Citations: 8     
  53. Pitman RK, Milad MR, Igoe SA, Vangel MG, Orr SP, Tsareva A, Gamache K, Nader K. Systemic mifepristone blocks reconsolidation of cue-conditioned fear; propranolol prevents this effect. Behav Neurosci. 2011 Aug; 125(4):632-8. PMID: 21688892.
    Citations: 29     Fields:    Translation:Animals
  54. Brunet A, Poundja J, Tremblay J, Bui E, Thomas E, Orr SP, Azzoug A, Birmes P, Pitman RK. Trauma reactivation under the influence of propranolol decreases posttraumatic stress symptoms and disorder: 3 open-label trials. J Clin Psychopharmacol. 2011 Aug; 31(4):547-50. PMID: 21720237.
    Citations: 54     Fields:    Translation:HumansCTClinical Trials
  55. Shin LM, Bush G, Milad MR, Lasko NB, Brohawn KH, Hughes KC, Macklin ML, Gold AL, Karpf RD, Orr SP, Rauch SL, Pitman RK. Exaggerated activation of dorsal anterior cingulate cortex during cognitive interference: a monozygotic twin study of posttraumatic stress disorder. Am J Psychiatry. 2011 Sep; 168(9):979-85. PMID: 21724666.
    Citations: 62     Fields:    Translation:Humans
  56. Gold AL, Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Metzger LJ, Dougherty DD, Alpert NM, Fischman AJ, Pitman RK. Decreased regional cerebral blood flow in medial prefrontal cortex during trauma-unrelated stressful imagery in Vietnam veterans with post-traumatic stress disorder. Psychol Med. 2011 Dec; 41(12):2563-72. PMID: 21733221.
    Citations: 17     Fields:    Translation:Humans
  57. Pitman RK. Will reconsolidation blockade offer a novel treatment for posttraumatic stress disorder? Front Behav Neurosci. 2011; 5:11. PMID: 21427793.
    Citations: 19     
  58. Hoge EA, Worthington JJ, Nagurney JT, Chang Y, Kay EB, Feterowski CM, Katzman AR, Goetz JM, Rosasco ML, Lasko NB, Zusman RM, Pollack MH, Orr SP, Pitman RK. Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery. CNS Neurosci Ther. 2012 Jan; 18(1):21-7. PMID: 22070357.
    Citations: 56     Fields:    Translation:Humans
  59. Pitman RK. A recent VA rules change and the traumatic event requirement in PTSD. JAMA. 2010 Dec 01; 304(21):2409-10. PMID: 21119089.
    Citations:    Fields:    Translation:Humans
  60. Pitman RK, Kaelin D, Zafonte R. Point/Counterpoint. Posttraumatic stress disorder versus traumatic brain injury. PM R. 2010 Nov; 2(11):1051-4. PMID: 21093841.
    Citations:    Fields:    Translation:Humans
  61. Gilbertson MW, McFarlane AC, Weathers FW, Keane TM, Yehuda R, Shalev AY, Lasko NB, Goetz JM, Pitman RK. Is trauma a causal agent of psychopathologic symptoms in posttraumatic stress disorder? Findings from identical twins discordant for combat exposure. J Clin Psychiatry. 2010 Oct; 71(10):1324-30. PMID: 20868640.
    Citations: 8     Fields:    Translation:Humans
  62. Pitman RK. Posttraumatic stress disorder and dementia: what is the origin of the association? JAMA. 2010 Jun 09; 303(22):2287-8. PMID: 20540170.
    Citations: 5     Fields:    
  63. Milad MR, Zeidan MA, Contero A, Pitman RK, Klibanski A, Rauch SL, Goldstein JM. The influence of gonadal hormones on conditioned fear extinction in healthy humans. Neuroscience. 2010 Jul 14; 168(3):652-8. PMID: 20412837.
    Citations: 97     Fields:    Translation:Humans
  64. Rougemont-Bücking A, Linnman C, Zeffiro TA, Zeidan MA, Lebron-Milad K, Rodriguez-Romaguera J, Rauch SL, Pitman RK, Milad MR. Altered processing of contextual information during fear extinction in PTSD: an fMRI study. CNS Neurosci Ther. 2011 Aug; 17(4):227-36. PMID: 20406268.
    Citations: 92     Fields:    Translation:Humans
  65. Shin LM, Lasko NB, Macklin ML, Karpf RD, Milad MR, Orr SP, Goetz JM, Fischman AJ, Rauch SL, Pitman RK. Resting metabolic activity in the cingulate cortex and vulnerability to posttraumatic stress disorder. Arch Gen Psychiatry. 2009 Oct; 66(10):1099-107. PMID: 19805700.
    Citations: 49     Fields:    Translation:Humans
  66. Hölzel BK, Carmody J, Evans KC, Hoge EA, Dusek JA, Morgan L, Pitman RK, Lazar SW. Stress reduction correlates with structural changes in the amygdala. Soc Cogn Affect Neurosci. 2010 Mar; 5(1):11-7. PMID: 19776221.
    Citations: 119     Fields:    Translation:Humans
  67. Milad MR, Pitman RK, Ellis CB, Gold AL, Shin LM, Lasko NB, Zeidan MA, Handwerger K, Orr SP, Rauch SL. Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder. Biol Psychiatry. 2009 Dec 15; 66(12):1075-82. PMID: 19748076.
    Citations: 445     Fields:    Translation:Humans
  68. Elman I, Lowen S, Frederick BB, Chi W, Becerra L, Pitman RK. Functional neuroimaging of reward circuitry responsivity to monetary gains and losses in posttraumatic stress disorder. Biol Psychiatry. 2009 Dec 15; 66(12):1083-90. PMID: 19640506.
    Citations: 55     Fields:    Translation:Humans
  69. Gruber RP, Roberts C, Schooler W, Pitman RK. Preventing postsurgical dissatisfaction syndrome after rhinoplasty with propranolol: a pilot study. Plast Reconstr Surg. 2009 Mar; 123(3):1072-1078. PMID: 19319076.
    Citations: 3     Fields:    Translation:Humans
  70. Love J, Sonnenberg P, Glynn JR, Gibson A, Gopaul K, Fang Z, Le Brun F, Pitman R, Hayward AC, Innes J, Van den Bosch C, Delpech V, Drobniewski F, Watson JM. Molecular epidemiology of tuberculosis in England, 1998. Int J Tuberc Lung Dis. 2009 Feb; 13(2):201-7. PMID: 19146748.
    Citations: 12     Fields:    Translation:HumansCells
  71. Pace-Schott EF, Milad MR, Orr SP, Rauch SL, Stickgold R, Pitman RK. Sleep promotes generalization of extinction of conditioned fear. Sleep. 2009 Jan; 32(1):19-26. PMID: 19189775.
    Citations: 58     Fields:    Translation:Humans
  72. MacNeill SJ, Goddard F, Pitman R, Tharme S, Cullinan P. Childhood peak flow and the Oxford Transport Strategy. Thorax. 2009 Aug; 64(8):651-6. PMID: 19052055.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  73. Holt DJ, Lebron-Milad K, Milad MR, Rauch SL, Pitman RK, Orr SP, Cassidy BS, Walsh JP, Goff DC. Extinction memory is impaired in schizophrenia. Biol Psychiatry. 2009 Mar 15; 65(6):455-63. PMID: 18986648.
    Citations: 78     Fields:    Translation:Humans
  74. Metzger LJ, Carson MA, Lasko NB, Paulus LA, Orr SP, Pitman RK, Yehuda R. Basal and suppressed salivary cortisol in female Vietnam nurse veterans with and without PTSD. Psychiatry Res. 2008 Dec 15; 161(3):330-5. PMID: 18951637.
    Citations: 7     Fields:    Translation:Humans
  75. Metzger LJ, Clark CR, McFarlane AC, Veltmeyer MD, Lasko NB, Paige SR, Pitman RK, Orr SP. Event-related potentials to auditory stimuli in monozygotic twins discordant for combat: association with PTSD. Psychophysiology. 2009 Jan; 46(1):172-8. PMID: 18803598.
    Citations: 6     Fields:    Translation:Humans
  76. Milad MR, Orr SP, Lasko NB, Chang Y, Rauch SL, Pitman RK. Presence and acquired origin of reduced recall for fear extinction in PTSD: results of a twin study. J Psychiatr Res. 2008 Jun; 42(7):515-20. PMID: 18313695.
    Citations: 189     Fields:    Translation:Humans
  77. Hopper JW, Pitman RK, Su Z, Heyman GM, Lasko NB, Macklin ML, Orr SP, Lukas SE, Elman I. Probing reward function in posttraumatic stress disorder: expectancy and satisfaction with monetary gains and losses. J Psychiatr Res. 2008 Aug; 42(10):802-7. PMID: 18068725.
    Citations: 29     Fields:    Translation:Humans
  78. Metzger LJ, Pitman RK, Miller GA, Paige SR, Orr SP. Intensity dependence of auditory P2 in monozygotic twins discordant for Vietnam combat: associations with posttraumatic stress disorder. J Rehabil Res Dev. 2008; 45(3):437-49. PMID: 18629752.
    Citations: 7     Fields:    Translation:Humans
  79. Pitman RK. Commentary: synthesis and perspectives. Prog Brain Res. 2008; 167:249-54. PMID: 18037020.
    Citations:    Fields:    Translation:HumansAnimals
  80. Elman I, Chi WH, Gurvits TV, Ryan ET, Lasko NB, Lukas SE, Pitman RK. Impaired reproduction of three-dimensional objects by cocaine-dependent subjects. J Neuropsychiatry Clin Neurosci. 2008; 20(4):478-84. PMID: 19196934.
    Citations: 1     Fields:    Translation:Humans
  81. Hinton DE, Hofmann SG, Pitman RK, Pollack MH, Barlow DH. The panic attack-posttraumatic stress disorder model: applicability to orthostatic panic among Cambodian refugees. Cogn Behav Ther. 2008; 37(2):101-16. PMID: 18470741.
    Citations: 18     Fields:    Translation:Humans
  82. Videlock EJ, Peleg T, Segman R, Yehuda R, Pitman RK, Shalev AY. Stress hormones and post-traumatic stress disorder in civilian trauma victims: a longitudinal study. Part II: the adrenergic response. Int J Neuropsychopharmacol. 2008 May; 11(3):373-80. PMID: 17971259.
    Citations: 19     Fields:    Translation:Humans
  83. Shalev AY, Videlock EJ, Peleg T, Segman R, Pitman RK, Yehuda R. Stress hormones and post-traumatic stress disorder in civilian trauma victims: a longitudinal study. Part I: HPA axis responses. Int J Neuropsychopharmacol. 2008 May; 11(3):365-72. PMID: 17971262.
    Citations: 37     Fields:    Translation:Humans
  84. Shin LM, Bush G, Whalen PJ, Handwerger K, Cannistraro PA, Wright CI, Martis B, Macklin ML, Lasko NB, Orr SP, Pitman RK, Rauch SL. Dorsal anterior cingulate function in posttraumatic stress disorder. J Trauma Stress. 2007 Oct; 20(5):701-12. PMID: 17955522.
    Citations: 33     Fields:    Translation:Humans
  85. Friedman MJ, Pitman RK. New findings on the neurobiology of posttraumatic stress disorder. J Trauma Stress. 2007 Oct; 20(5):653-5. PMID: 17955528.
    Citations: 2     Fields:    Translation:Humans
  86. Carson MA, Metzger LJ, Lasko NB, Paulus LA, Morse AE, Pitman RK, Orr SP. Physiologic reactivity to startling tones in female Vietnam nurse veterans with PTSD. J Trauma Stress. 2007 Oct; 20(5):657-66. PMID: 17955532.
    Citations: 10     Fields:    Translation:Humans
  87. Kasai K, Yamasue H, Gilbertson MW, Shenton ME, Rauch SL, Pitman RK. Evidence for acquired pregenual anterior cingulate gray matter loss from a twin study of combat-related posttraumatic stress disorder. Biol Psychiatry. 2008 Mar 15; 63(6):550-6. PMID: 17825801.
    Citations: 87     Fields:    Translation:Humans
  88. Milad MR, Quirk GJ, Pitman RK, Orr SP, Fischl B, Rauch SL. A role for the human dorsal anterior cingulate cortex in fear expression. Biol Psychiatry. 2007 Nov 15; 62(10):1191-4. PMID: 17707349.
    Citations: 189     Fields:    Translation:Humans
  89. Brunet A, Orr SP, Tremblay J, Robertson K, Nader K, Pitman RK. Effect of post-retrieval propranolol on psychophysiologic responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder. J Psychiatr Res. 2008 May; 42(6):503-6. PMID: 17588604.
    Citations: 165     Fields:    Translation:Humans
  90. Gilbertson MW, Williston SK, Paulus LA, Lasko NB, Gurvits TV, Shenton ME, Pitman RK, Orr SP. Configural cue performance in identical twins discordant for posttraumatic stress disorder: theoretical implications for the role of hippocampal function. Biol Psychiatry. 2007 Sep 01; 62(5):513-20. PMID: 17509537.
    Citations: 32     Fields:    Translation:Humans
  91. Buhlmann U, Wilhelm S, Deckersbach T, Rauch SL, Pitman RK, Orr SP. Physiologic responses to loud tones in individuals with obsessive-compulsive disorder. Psychosom Med. 2007 Feb-Mar; 69(2):166-72. PMID: 17289827.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  92. Milad MR, Wright CI, Orr SP, Pitman RK, Quirk GJ, Rauch SL. Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert. Biol Psychiatry. 2007 Sep 01; 62(5):446-54. PMID: 17217927.
    Citations: 416     Fields:    Translation:Humans
  93. Milad MR, Goldstein JM, Orr SP, Wedig MM, Klibanski A, Pitman RK, Rauch SL. Fear conditioning and extinction: influence of sex and menstrual cycle in healthy humans. Behav Neurosci. 2006 Dec; 120(6):1196-203. PMID: 17201462.
    Citations: 78     Fields:    Translation:Humans
  94. Levitt JJ, Chen QC, May FS, Gilbertson MW, Shenton ME, Pitman RK. Volume of cerebellar vermis in monozygotic twins discordant for combat exposure: lack of relationship to post-traumatic stress disorder. Psychiatry Res. 2006 Dec 01; 148(2-3):143-9. PMID: 17097862.
    Citations: 2     Fields:    Translation:Humans
  95. Gilbertson MW, Paulus LA, Williston SK, Gurvits TV, Lasko NB, Pitman RK, Orr SP. Neurocognitive function in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorder. J Abnorm Psychol. 2006 Aug; 115(3):484-95. PMID: 16866589.
    Citations: 43     Fields:    Translation:Humans
  96. Orr SP, Milad MR, Metzger LJ, Lasko NB, Gilbertson MW, Pitman RK. Effects of beta blockade, PTSD diagnosis, and explicit threat on the extinction and retention of an aversively conditioned response. Biol Psychol. 2006 Oct; 73(3):262-71. PMID: 16828533.
    Citations: 23     Fields:    Translation:Humans
  97. Pitman RK, Gilbertson MW, Gurvits TV, May FS, Lasko NB, Metzger LJ, Shenton ME, Yehuda R, Orr SP. Clarifying the origin of biological abnormalities in PTSD through the study of identical twins discordant for combat exposure. Ann N Y Acad Sci. 2006 Jul; 1071:242-54. PMID: 16891575.
    Citations: 44     Fields:    Translation:Humans
  98. Shin LM, Rauch SL, Pitman RK. Amygdala, medial prefrontal cortex, and hippocampal function in PTSD. Ann N Y Acad Sci. 2006 Jul; 1071:67-79. PMID: 16891563.
    Citations: 308     Fields:    Translation:Humans
  99. Hinton DE, Chhean D, Pich V, Pollack MH, Orr SP, Pitman RK. Assessment of posttraumatic stress disorder in Cambodian refugees using the Clinician-Administered PTSD Scale: psychometric properties and symptom severity. J Trauma Stress. 2006 Jun; 19(3):405-9. PMID: 16788999.
    Citations: 9     Fields:    Translation:Humans
  100. Gurvits TV, Metzger LJ, Lasko NB, Cannistraro PA, Tarhan AS, Gilbertson MW, Orr SP, Charbonneau AM, Wedig MM, Pitman RK. Subtle neurologic compromise as a vulnerability factor for combat-related posttraumatic stress disorder: results of a twin study. Arch Gen Psychiatry. 2006 May; 63(5):571-6. PMID: 16651514.
    Citations: 17     Fields:    Translation:Humans
  101. Coker R, Bell A, Pitman R, Zellweger JP, Heldal E, Hayward A, Skulberg A, Bothamley G, Whitfield R, de Vries G, Watson JM. Tuberculosis screening in migrants in selected European countries shows wide disparities. Eur Respir J. 2006 Apr; 27(4):801-7. PMID: 16585088.
    Citations: 17     Fields:    Translation:HumansPHPublic Health
  102. Pollack MH, Simon NM, Fagiolini A, Pitman R, McNally RJ, Nierenberg AA, Miyahara S, Sachs GS, Perlman C, Ghaemi SN, Thase ME, Otto MW. Persistent posttraumatic stress disorder following September 11 in patients with bipolar disorder. J Clin Psychiatry. 2006 Mar; 67(3):394-9. PMID: 16649825.
    Citations: 9     Fields:    Translation:Humans
  103. Milad MR, Rauch SL, Pitman RK, Quirk GJ. Fear extinction in rats: implications for human brain imaging and anxiety disorders. Biol Psychol. 2006 Jul; 73(1):61-71. PMID: 16476517.
    Citations: 215     Fields:    Translation:HumansAnimals
  104. Pitman RK. Combat effects on mental health: the more things change, the more they remain the same. Arch Gen Psychiatry. 2006 Feb; 63(2):127-8. PMID: 16461853.
    Citations: 1     Fields:    Translation:Humans
  105. Rauch SL, Milad MR, Orr SP, Quinn BT, Fischl B, Pitman RK. Orbitofrontal thickness, retention of fear extinction, and extraversion. Neuroreport. 2005 Nov 28; 16(17):1909-12. PMID: 16272877.
    Citations: 48     Fields:    Translation:Humans
  106. Milad MR, Quinn BT, Pitman RK, Orr SP, Fischl B, Rauch SL. Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory. Proc Natl Acad Sci U S A. 2005 Jul 26; 102(30):10706-11. PMID: 16024728.
    Citations: 151     Fields:    Translation:Humans
  107. Milad MR, Orr SP, Pitman RK, Rauch SL. Context modulation of memory for fear extinction in humans. Psychophysiology. 2005 Jul; 42(4):456-64. PMID: 16008774.
    Citations: 86     Fields:    Translation:HumansCTClinical Trials
  108. Elman I, Ariely D, Mazar N, Aharon I, Lasko NB, Macklin ML, Orr SP, Lukas SE, Pitman RK. Probing reward function in post-traumatic stress disorder with beautiful facial images. Psychiatry Res. 2005 Jun 30; 135(3):179-83. PMID: 15993948.
    Citations: 31     Fields:    Translation:Humans
  109. Shin LM, Wright CI, Cannistraro PA, Wedig MM, McMullin K, Martis B, Macklin ML, Lasko NB, Cavanagh SR, Krangel TS, Orr SP, Pitman RK, Whalen PJ, Rauch SL. A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder. Arch Gen Psychiatry. 2005 Mar; 62(3):273-81. PMID: 15753240.
    Citations: 290     Fields:    Translation:Humans
  110. Pitman RK, Delahanty DL. Conceptually driven pharmacologic approaches to acute trauma. CNS Spectr. 2005 Feb; 10(2):99-106. PMID: 15685120.
    Citations: 52     Fields:    Translation:HumansAnimals
  111. Zatzick DF, Russo J, Pitman RK, Rivara F, Jurkovich G, Roy-Byrne P. Reevaluating the association between emergency department heart rate and the development of posttraumatic stress disorder: A public health approach. Biol Psychiatry. 2005 Jan 01; 57(1):91-5. PMID: 15607305.
    Citations: 17     Fields:    Translation:HumansPHPublic Health
  112. Roy-Byrne P, Arguelles L, Vitek ME, Goldberg J, Keane TM, True WR, Pitman RK. Persistence and change of PTSD symptomatology--a longitudinal co-twin control analysis of the Vietnam Era Twin Registry. Soc Psychiatry Psychiatr Epidemiol. 2004 Sep; 39(9):681-5. PMID: 15672287.
    Citations: 7     Fields:    Translation:Humans
  113. McNally RJ, Lasko NB, Clancy SA, Macklin ML, Pitman RK, Orr SP. Psychophysiological responding during script-driven imagery in people reporting abduction by space aliens. Psychol Sci. 2004 Jul; 15(7):493-7. PMID: 15200635.
    Citations: 9     Fields:    Translation:Humans
  114. Metzger LJ, Paige SR, Carson MA, Lasko NB, Paulus LA, Pitman RK, Orr SP. PTSD arousal and depression symptoms associated with increased right-sided parietal EEG asymmetry. J Abnorm Psychol. 2004 May; 113(2):324-9. PMID: 15122952.
    Citations: 29     Fields:    Translation:Humans
  115. May FS, Chen QC, Gilbertson MW, Shenton ME, Pitman RK. Cavum septum pellucidum in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorder. Biol Psychiatry. 2004 Mar 15; 55(6):656-8. PMID: 15013837.
    Citations: 14     Fields:    Translation:Humans
  116. Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Peters PM, Metzger LJ, Dougherty DD, Cannistraro PA, Alpert NM, Fischman AJ, Pitman RK. Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Arch Gen Psychiatry. 2004 Feb; 61(2):168-76. PMID: 14757593.
    Citations: 231     Fields:    Translation:Humans
  117. Shin LM, Shin PS, Heckers S, Krangel TS, Macklin ML, Orr SP, Lasko N, Segal E, Makris N, Richert K, Levering J, Schacter DL, Alpert NM, Fischman AJ, Pitman RK, Rauch SL. Hippocampal function in posttraumatic stress disorder. Hippocampus. 2004; 14(3):292-300. PMID: 15132428.
    Citations: 66     Fields:    Translation:Humans
  118. Roy-Byrne PP, Russo J, Michelson E, Zatzick D, Pitman RK, Berliner L. Risk factors and outcome in ambulatory assault victims presenting to the acute emergency department setting: implications for secondary prevention studies in PTSD. Depress Anxiety. 2004; 19(2):77-84. PMID: 15022142.
    Citations: 11     Fields:    Translation:Humans
  119. Bonne O, Brandes D, Segman R, Pitman RK, Yehuda R, Shalev AY. Prospective evaluation of plasma cortisol in recent trauma survivors with posttraumatic stress disorder. Psychiatry Res. 2003 Jul 15; 119(1-2):171-5. PMID: 12860372.
    Citations: 12     Fields:    Translation:Humans
  120. Rauch SL, Shin LM, Segal E, Pitman RK, Carson MA, McMullin K, Whalen PJ, Makris N. Selectively reduced regional cortical volumes in post-traumatic stress disorder. Neuroreport. 2003 May 23; 14(7):913-6. PMID: 12802174.
    Citations: 69     Fields:    Translation:Humans
  121. Orr SP, Metzger LJ, Lasko NB, Macklin ML, Hu FB, Shalev AY, Pitman RK. Physiologic responses to sudden, loud tones in monozygotic twins discordant for combat exposure: association with posttraumatic stress disorder. Arch Gen Psychiatry. 2003 Mar; 60(3):283-8. PMID: 12622661.
    Citations: 57     Fields:    Translation:Humans
  122. Roy-Byrne P, Berliner L, Russo J, Zatzick D, Pitman RK. Treatment preferences and determinants in victims of sexual and physical assault. J Nerv Ment Dis. 2003 Mar; 191(3):161-5. PMID: 12637842.
    Citations: 17     Fields:    Translation:Humans
  123. Hagengimana A, Hinton D, Bird B, Pollack M, Pitman RK. Somatic panic-attack equivalents in a community sample of Rwandan widows who survived the 1994 genocide. Psychiatry Res. 2003 Jan 25; 117(1):1-9. PMID: 12581815.
    Citations: 11     Fields:    Translation:Humans
  124. Gurvits TV, Lasko NB, Repak AL, Metzger LJ, Orr SP, Pitman RK. Performance on visuospatial copying tasks in individuals with chronic posttraumatic stress disorder. Psychiatry Res. 2002 Nov 15; 112(3):263-8. PMID: 12450636.
    Citations: 6     Fields:    Translation:Humans
  125. Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, Pitman RK. Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci. 2002 Nov; 5(11):1242-7. PMID: 12379862.
    Citations: 357     Fields:    Translation:Humans
  126. Clancy SA, McNally RJ, Schacter DL, Lenzenweger MF, Pitman RK. Memory distortion in people reporting abduction by aliens. J Abnorm Psychol. 2002 Aug; 111(3):455-61. PMID: 12150421.
    Citations: 14     Fields:    Translation:Humans
  127. Maguire H, Dale JW, McHugh TD, Butcher PD, Gillespie SH, Costetsos A, Al-Ghusein H, Holland R, Dickens A, Marston L, Wilson P, Pitman R, Strachan D, Drobniewski FA, Banerjee DK. Molecular epidemiology of tuberculosis in London 1995-7 showing low rate of active transmission. Thorax. 2002 Jul; 57(7):617-22. PMID: 12096206.
    Citations: 39     Fields:    Translation:HumansCells
  128. Orr SP, Metzger LJ, Pitman RK. Psychophysiology of post-traumatic stress disorder. Psychiatr Clin North Am. 2002 Jun; 25(2):271-93. PMID: 12136501.
    Citations: 39     Fields:    Translation:Humans
  129. Gurvits TV, Carson MA, Metzger L, Croteau HB, Lasko NB, Orr SP, Pitman RK. Absence of selected neurological soft signs in Vietnam nurse veterans with post-traumatic stress disorder. Psychiatry Res. 2002 May 15; 110(1):81-5. PMID: 12007596.
    Citations: 3     Fields:    Translation:Humans
  130. Pitman RK, Sanders KM, Zusman RM, Healy AR, Cheema F, Lasko NB, Cahill L, Orr SP. Pilot study of secondary prevention of posttraumatic stress disorder with propranolol. Biol Psychiatry. 2002 Jan 15; 51(2):189-92. PMID: 1