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Elvira Isganaitis, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21HD091974 (PATTI, MARY E) Dec 30, 2017 - Nov 30, 2019
    NIH/NICHD
    Impact of Metabolic Health in Type 2 Diabetes on Sperm Epigenetic Marks in Humans: A Novel Intergenerational Mechanism for Metabolic Disease Risk Transmission
    Role: Co-Principal Investigator
  2. R00HD064793 (ISGANAITIS, ELVIRA MARIE) Sep 30, 2010 - Nov 30, 2015
    NIH/NICHD
    Pathways of Mother to Child Transmission of Metabolic Risk
    Role: Principal Investigator
  3. K99HD064793 (ISGANAITIS, ELVIRA MARIE) Sep 30, 2010 - Nov 30, 2012
    NIH/NICHD
    Elucidating adiposity in a mouse model of prenatal undernutrition
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Isganaitis E, Venditti S, Matthews TJ, Lerin C, Demerath EW, Fields DA. Maternal obesity and the human milk metabolome: associations with infant body composition and postnatal weight gain. Am J Clin Nutr. 2019 Apr 04. PMID: 30968129.
    Citations:    
  2. Brown FM, Isganaitis E, James-Todd T. Much to HAPO FUS About: Increasing Maternal Glycemia in Pregnancy Is Associated With Worsening Childhood Glucose Metabolism. Diabetes Care. 2019 Mar; 42(3):393-395. PMID: 30787060.
    Citations:    
  3. Mulla BM, Noor N, James-Todd T, Isganaitis E, Takoudes TC, Curran A, Warren CE, O'Brien KE, Brown FM. Continuous Glucose Monitoring, Glycemic Variability, and Excessive Fetal Growth in Pregnancies Complicated by Type 1 Diabetes. Diabetes Technol Ther. 2018 06; 20(6):413-419. PMID: 29901410.
    Citations:    Fields:    Translation:Humans
  4. Bauman V, Sturkey AC, Sherafat-Kazemzadeh R, McEwan J, Jones PM, Keating A, Isganaitis E, Ricker A, Rother KI. Factitious hypoglycemia in children and adolescents with diabetes. Pediatr Diabetes. 2018 06; 19(4):823-831. PMID: 29464887.
    Citations:    Fields:    
  5. Ma H, Sales VM, Wolf AR, Subramanian S, Matthews TJ, Chen M, Sharma A, Gall W, Kulik W, Cohen DE, Adachi Y, Griffin NW, Gordon JI, Patti ME, Isganaitis E. Attenuated Effects of Bile Acids on Glucose Metabolism and Insulin Sensitivity in a Male Mouse Model of Prenatal Undernutrition. Endocrinology. 2017 08 01; 158(8):2441-2452. PMID: 28637315.
    Citations:    Fields:    Translation:Animals
  6. Ferris HA, Isganaitis E, Brown F. Time for an End to Juice in the Special Supplemental Nutrition Program for Women, Infants, and Children. JAMA Pediatr. 2017 06 01; 171(6):509-510. PMID: 28437541.
    Citations: 1     Fields:    
  7. Isganaitis E, Suehiro H, Cardona C. Who's your daddy?: paternal inheritance of metabolic disease risk. Curr Opin Endocrinol Diabetes Obes. 2017 Feb; 24(1):47-55. PMID: 27906710.
    Citations: 3     Fields:    Translation:HumansCells
  8. Costa SM, Isganaitis E, Matthews TJ, Hughes K, Daher G, Dreyfuss JM, da Silva GA, Patti ME. Maternal obesity programs mitochondrial and lipid metabolism gene expression in infant umbilical vein endothelial cells. Int J Obes (Lond). 2016 11; 40(11):1627-1634. PMID: 27531045.
    Citations: 3     Fields:    Translation:HumansCells
  9. Lerin C, Goldfine AB, Boes T, Liu M, Kasif S, Dreyfuss JM, De Sousa-Coelho AL, Daher G, Manoli I, Sysol JR, Isganaitis E, Jessen N, Goodyear LJ, Beebe K, Gall W, Venditti CP, Patti ME. Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism. Mol Metab. 2016 Oct; 5(10):926-936. PMID: 27689005.
    Citations: 15     Fields:    
  10. Gonzalez-Franquesa A, Burkart AM, Isganaitis E, Patti ME. What Have Metabolomics Approaches Taught Us About Type 2 Diabetes? Curr Diab Rep. 2016 08; 16(8):74. PMID: 27319324.
    Citations: 3     Fields:    Translation:Humans
  11. Isganaitis E, Rifas-Shiman SL, Oken E, Dreyfuss JM, Gall W, Gillman MW, Patti ME. Associations of cord blood metabolites with early childhood obesity risk. Int J Obes (Lond). 2015 Jul; 39(7):1041-8. PMID: 25804930.
    Citations: 9     Fields:    Translation:Humans
  12. Hivert MF, Perng W, Watkins SM, Newgard CS, Kenny LC, Kristal BS, Patti ME, Isganaitis E, DeMeo DL, Oken E, Gillman MW. Metabolomics in the developmental origins of obesity and its cardiometabolic consequences. J Dev Orig Health Dis. 2015 Apr; 6(2):65-78. PMID: 25631626.
    Citations: 3     Fields:    Translation:HumansAnimals
  13. Perng W, Gillman MW, Fleisch AF, Michalek RD, Watkins SM, Isganaitis E, Patti ME, Oken E. Metabolomic profiles and childhood obesity. Obesity (Silver Spring). 2014 Dec; 22(12):2570-8. PMID: 25251340.
    Citations: 28     Fields:    Translation:Humans
  14. Radford EJ, Ito M, Shi H, Corish JA, Yamazawa K, Isganaitis E, Seisenberger S, Hore TA, Reik W, Erkek S, Peters AHFM, Patti ME, Ferguson-Smith AC. In utero effects. In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism. Science. 2014 Aug 15; 345(6198):1255903. PMID: 25011554.
    Citations: 118     Fields:    Translation:AnimalsCells
  15. Huang T, Saxena AR, Isganaitis E, James-Todd T. Gender and racial/ethnic differences in the associations of urinary phthalate metabolites with markers of diabetes risk: National Health and Nutrition Examination Survey 2001-2008. Environ Health. 2014 Feb 05; 13(1):6. PMID: 24499162.
    Citations: 18     Fields:    Translation:HumansPHPublic Health
  16. Isganaitis E, Woo M, Ma H, Chen M, Kong W, Lytras A, Sales V, Decoste-Lopez J, Lee KJ, Leatherwood C, Lee D, Fitzpatrick C, Gall W, Watkins S, Patti ME. Developmental programming by maternal insulin resistance: hyperinsulinemia, glucose intolerance, and dysregulated lipid metabolism in male offspring of insulin-resistant mice. Diabetes. 2014 Feb; 63(2):688-700. PMID: 24186867.
    Citations: 15     Fields:    Translation:Animals
  17. Colaneri A, Wang T, Pagadala V, Kittur J, Staffa NG, Peddada SD, Isganaitis E, Patti ME, Birnbaumer L. A minimal set of tissue-specific hypomethylated CpGs constitute epigenetic signatures of developmental programming. PLoS One. 2013; 8(9):e72670. PMID: 24069155.
    Citations: 8     Fields:    Translation:AnimalsCells
  18. Radford EJ, Isganaitis E, Jimenez-Chillaron J, Schroeder J, Molla M, Andrews S, Didier N, Charalambous M, McEwen K, Marazzi G, Sassoon D, Patti ME, Ferguson-Smith AC. An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming. PLoS Genet. 2012; 8(4):e1002605. PMID: 22511876.
    Citations: 44     Fields:    Translation:HumansAnimals
  19. Woo M, Isganaitis E, Cerletti M, Fitzpatrick C, Wagers AJ, Jimenez-Chillaron J, Patti ME. Early life nutrition modulates muscle stem cell number: implications for muscle mass and repair. Stem Cells Dev. 2011 Oct; 20(10):1763-9. PMID: 21247245.
    Citations: 27     Fields:    Translation:AnimalsCells
  20. Isganaitis E, Jimenez-Chillaron J, Woo M, Chow A, DeCoste J, Vokes M, Liu M, Kasif S, Zavacki AM, Leshan RL, Myers MG, Patti ME. Accelerated postnatal growth increases lipogenic gene expression and adipocyte size in low-birth weight mice. Diabetes. 2009 May; 58(5):1192-200. PMID: 19208909.
    Citations: 29     Fields:    Translation:AnimalsCells
  21. Jimenez-Chillaron JC, Isganaitis E, Charalambous M, Gesta S, Pentinat-Pelegrin T, Faucette RR, Otis JP, Chow A, Diaz R, Ferguson-Smith A, Patti ME. Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice. Diabetes. 2009 Feb; 58(2):460-8. PMID: 19017762.
    Citations: 82     Fields:    Translation:Animals
  22. Isganaitis E, Levitsky LL. Preventing childhood obesity: can we do it? Curr Opin Endocrinol Diabetes Obes. 2008 Feb; 15(1):1-8. PMID: 18185057.
    Citations: 7     Fields:    Translation:Humans
  23. Oge A, Isganaitis E, Jimenez-Chillaron J, Reamer C, Faucette R, Barry K, Przybyla R, Patti ME. In utero undernutrition reduces diabetes incidence in non-obese diabetic mice. Diabetologia. 2007 May; 50(5):1099-108. PMID: 17370059.
    Citations: 6     Fields:    Translation:Animals
  24. Isganaitis E, Lustig RH. Fast food, central nervous system insulin resistance, and obesity. Arterioscler Thromb Vasc Biol. 2005 Dec; 25(12):2451-62. PMID: 16166564.
    Citations: 33     Fields:    Translation:HumansAnimalsPHPublic Health
  25. Isganaitis E, Kamei R, Kohrman AF. Spare the rod and save the child. Virtual Mentor. 2003 Aug 01; 5(8). PMID: 23267533.
    Citations:    Fields:    
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.