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George Liang King, M.D.

Concepts

This page shows the publications George King has written about Receptor, Insulin.
Connection Strength

2.132
  1. Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes. Nat Commun. 2019 09 27; 10(1):4427.
    View in: PubMed
    Score: 0.602
  2. Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arterioscler Thromb Vasc Biol. 2006 Apr; 26(4):787-93.
    View in: PubMed
    Score: 0.234
  3. Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award Lecture. Diabetes. 2016 06; 65(6):1462-71.
    View in: PubMed
    Score: 0.120
  4. Characterization of phorbol ester-stimulated serine phosphorylation of the human insulin receptor. Biochem J. 1994 Oct 01; 303 ( Pt 1):43-50.
    View in: PubMed
    Score: 0.106
  5. Glomerular-specific protein kinase C-ß-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity. Kidney Int. 2011 Apr; 79(8):883-96.
    View in: PubMed
    Score: 0.082
  6. Diabetes: Podocytes lose their footing. Nature. 2010 Nov 04; 468(7320):42-4.
    View in: PubMed
    Score: 0.081
  7. Insulin receptor recycling in vascular endothelial cells. Regulation by insulin and phorbol ester. J Biol Chem. 1989 Apr 05; 264(10):5916-23.
    View in: PubMed
    Score: 0.073
  8. Identification of persistent defects in insulin receptor structure and function capillary endothelial cells from diabetic rats. J Clin Invest. 1989 Jan; 83(1):127-36.
    View in: PubMed
    Score: 0.071
  9. Intracellular pathways of insulin transport across vascular endothelial cells. Am J Physiol. 1988 Oct; 255(4 Pt 1):C459-64.
    View in: PubMed
    Score: 0.070
  10. Receptors for and effects of insulin and IGF-I in rat glomerular mesangial cells. Am J Physiol. 1988 Mar; 254(3 Pt 1):C411-6.
    View in: PubMed
    Score: 0.067
  11. Regulation of insulin receptor internalization in vascular endothelial cells by insulin and phorbol ester. J Biol Chem. 1987 May 05; 262(13):6417-24.
    View in: PubMed
    Score: 0.064
  12. Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain. FASEB J. 2006 Jun; 20(8):1203-5.
    View in: PubMed
    Score: 0.059
  13. Characterization of the receptors for insulin and the insulin-like growth factors on micro- and macrovascular tissues. Endocrinology. 1985 Sep; 117(3):1222-9.
    View in: PubMed
    Score: 0.057
  14. Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. J Clin Invest. 2003 Jun; 111(12):1835-42.
    View in: PubMed
    Score: 0.049
  15. The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest. 2003 May; 111(9):1373-80.
    View in: PubMed
    Score: 0.048
  16. Sharing of biological effect and receptors between guinea pig insulin and platelet-derived growth factor. Proc Natl Acad Sci U S A. 1983 Mar; 80(5):1308-12.
    View in: PubMed
    Score: 0.048
  17. Interactions between the receptors for insulin and the insulin-like growth factors on adipocytes. J Biol Chem. 1982 Sep 10; 257(17):10001-6.
    View in: PubMed
    Score: 0.046
  18. Direct demonstration of separate receptors for growth and metabolic activities of insulin and multiplication-stimulating activity (an insulinlike growth factor) using antibodies to the insulin receptor. J Clin Invest. 1980 Jul; 66(1):130-40.
    View in: PubMed
    Score: 0.040
  19. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J Clin Invest. 1999 Aug; 104(4):447-57.
    View in: PubMed
    Score: 0.037
  20. Insulin stimulates serine and tyrosine phosphorylation in the juxtamembrane region of the insulin receptor. J Biol Chem. 1993 May 25; 268(15):11256-64.
    View in: PubMed
    Score: 0.024
  21. Characterization of induction of protooncogene c-myc and cellular growth in human vascular smooth muscle cells by insulin and IGF-I. Diabetes. 1989 Jan; 38(1):123-9.
    View in: PubMed
    Score: 0.018
  22. Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metab. 2008 Feb; 7(2):125-34.
    View in: PubMed
    Score: 0.017
  23. Processing and release of insulin and insulin-like growth factor I by macro- and microvascular endothelial cells. Endocrinology. 1986 Nov; 119(5):1904-13.
    View in: PubMed
    Score: 0.015
  24. Comparative studies on insulin-like growth factor II and insulin processing by vascular endothelial cells. Diabetes. 1986 Oct; 35(10):1065-72.
    View in: PubMed
    Score: 0.015
  25. Processing and transport of insulin by vascular endothelial cells. Effects of sulfonylureas on insulin receptors. Am J Med. 1985 Sep 20; 79(3B):43-7.
    View in: PubMed
    Score: 0.014
  26. Processing of insulin by bovine endothelial cells in culture. Internalization without degradation. Diabetes. 1984 Aug; 33(8):794-800.
    View in: PubMed
    Score: 0.013
  27. Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels. J Clin Invest. 1983 Apr; 71(4):974-9.
    View in: PubMed
    Score: 0.012
  28. Demonstration of receptors for insulin and insulin-like growth factors on Swarm rat chondrosarcoma chondrocytes. Evidence that insulin stimulates proteoglycan synthesis through the insulin receptor. J Biol Chem. 1982 Jan 25; 257(2):663-9.
    View in: PubMed
    Score: 0.011
  29. Autoantibodies to insulin receptors in man: immunological determinants and mechanism of action. Ciba Found Symp. 1982; (90):91-113.
    View in: PubMed
    Score: 0.011
  30. Insulin receptors, receptor antibodies, and the mechanism of insulin action. Recent Prog Horm Res. 1981; 37:477-538.
    View in: PubMed
    Score: 0.010
  31. Modulation of the insulin receptor by insulin receptor autoantibodies. Prog Clin Biol Res. 1980; 42:109-26.
    View in: PubMed
    Score: 0.010
  32. The human erythrocyte insulin-like growth factor I receptor: characterization and demonstration of ligand-stimulated autophosphorylation. J Clin Endocrinol Metab. 1986 Apr; 62(4):692-9.
    View in: PubMed
    Score: 0.004
  33. [B17-D-leucine]insulin and [B17-norleucine]insulin: synthesis and biological properties. Hoppe Seylers Z Physiol Chem. 1983 Nov; 364(11):1615-26.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.