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Christopher H Gibbons, M.D.

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Biography
1996 - 1997
American Heart Association Research Fellowship
1999
MD with Distinction in Immunologic Research
2002 - 2003
Chief Resident in Neurology, Johns Hopkins Hospital
2007
Fellowship Award, Peripheral Nerve Society
2007 - 2010
Council Member, Autonomic Section of the American Academy of Neurology
2007 - 2008
JDRF Career Development Award
2010
Board of Directors, American Autonomic Society
2011
PJ Dyck Award
2010 - 2013
Chair Elect, Autonomic Section of the American Academy of Neurology
2013
Chair, Autonomic Section of the American Academy of Neurology
2013 - 2014
President Elect, American Autonomic Society
2014 - 2015
President, American Autonomic Society

Overview
Dr. Gibbons is an Associate Professor of Neurology at Harvard Medical School and on staff at Beth Israel Deaconess Medical Center and Joslin Diabetes Center in Boston, Massachusetts.

Dr. Gibbons is director of the Joslin Diabetes Center Neuropathy Clinic. He is the director of the Neurocutaneous skin biopsy lab at Beth Israel Deaconess Medical Center. Dr. Gibbons is currently the Chair for the Autonomic Section of the American Academy of Neurology and President of the American Autonomic Society.

Dr. Gibbons is actively engaged in clinical/translational research and has published extensively on peripheral and autonomic neuropathies. His current areas of research include 1) defining the mechanisms and pathophysiology underlying the development of neuropathy in diabetes and 2) investigating the presence of cutaneous alpha-synuclein in neurodegenerative disorders. Dr. Gibbons has received research funding through the NIH (NINDS), the Goldberg Foundation and the Juvenile Diabetes Research Foundation.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K23NS050209 (GIBBONS, CHRISTOPHER H) May 1, 2008 - Oct 30, 2013
    NIH
    Structure & Function in Diabetic Small Fiber Neuropathy
    Role: Principal Investigator
  2. F32NS049899 (GIBBONS, CHRISTOPHER H) Jul 1, 2004 - Jun 30, 2007
    NIH
    Structure and Function: Diabetic Small Fiber Neuropathy
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gibbons CH, Klein MC. IVIG and Small Fiber Neuropathy: The Ongoing Search for Evidence. Neurology. 2021 Mar 25. PMID: 33766998.
    Citations:    Fields:    
  2. Levine TD, Bellaire B, Gibbons C, Freeman R. Cutaneous alpha-synuclein deposition in postural tachycardia patients. Ann Clin Transl Neurol. 2021 Mar 25. PMID: 33764697.
    Citations:    Fields:    
  3. Cheshire WP, Freeman R, Gibbons CH, Cortelli P, Wenning GK, Hilz MJ, Spies JM, Lipp A, Sandroni P, Wada N, Mano T, Kim HA, Kimpinski K, Iodice V, Idiáquez J, Thaisetthawatkul P, Coon EA, Low PA, Singer W. Corrigendum to "Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology" [Clin. Neurophysiol. 132(2) (2021) 666-682]. Clin Neurophysiol. 2021 Mar 05. PMID: 33685802.
    Citations:    Fields:    
  4. Gibbons CH, Silva G, Freeman R. Cardiovascular exercise as a treatment of postural orthostatic tachycardia syndrome: A pragmatic treatment trial. Heart Rhythm. 2021 Jan 19. PMID: 33482385.
    Citations: 1     Fields:    
  5. Cheshire WP, Freeman R, Gibbons CH, Cortelli P, Wenning GK, Hilz MJ, Spies JM, Lipp A, Sandroni P, Wada N, Mano A, Ah Kim H, Kimpinski K, Iodice V, Idiáquez J, Thaisetthawatkul P, Coon EA, Low PA, Singer W. Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology. Clin Neurophysiol. 2021 Feb; 132(2):666-682. PMID: 33419664.
    Citations: 1     Fields:    
  6. Freeman R, Gewandter JS, Faber CG, Gibbons C, Haroutounian S, Lauria G, Levine T, Malik RA, Singleton JR, Smith AG, Bell J, Dworkin RH, Feldman E, Herrmann DN, Hoke A, Kolb N, Mansikka H, Oaklander AL, Peltier A, Polydefkis M, Ritt E, Russell JW, Sainati S, Steiner D, Treister R, Üçeyler N. Idiopathic distal sensory polyneuropathy: ACTTION diagnostic criteria. Neurology. 2020 12 01; 95(22):1005-1014. PMID: 33055271.
    Citations:    Fields:    Translation:HumansCells
  7. Koulouris AE, Edwards RR, Dorado K, Schreiber KL, Lazaridou A, Rajan S, White J, Garcia J, Gibbons C, Freeman R. Reliability and Validity of the Boston Bedside Quantitative Sensory Testing Battery for Neuropathic Pain. Pain Med. 2020 10 01; 21(10):2336-2347. PMID: 32895703.
    Citations: 1     Fields:    
  8. Wang N, Garcia J, Freeman R, Gibbons CH. Phosphorylated Alpha-Synuclein Within Cutaneous Autonomic Nerves of Patients With Parkinson's Disease: The Implications of Sample Thickness on Results. J Histochem Cytochem. 2020 10; 68(10):669-678. PMID: 32921251.
    Citations:    Fields:    Translation:HumansCells
  9. Gibbons CH, Freeman R. Delayed orthostatic hypotension. Auton Neurosci. 2020 12; 229:102724. PMID: 32942225.
    Citations:    Fields:    
  10. Sohn E, Suh BC, Wang N, Freeman R, Gibbons CH. A novel method to quantify cutaneous vascular innervation. Muscle Nerve. 2020 10; 62(4):492-501. PMID: 32270499.
    Citations: 1     Fields:    Translation:Humans
  11. Freeman R, Illigens BMW, Lapusca R, Campagnolo M, Abuzinadah AR, Bonyhay I, Sinn DI, Miglis M, White J, Gibbons CH. Symptom Recognition Is Impaired in Patients With Orthostatic Hypotension. Hypertension. 2020 05; 75(5):1325-1332. PMID: 32223377.
    Citations: 7     Fields:    
  12. Olshansky B, Cannom D, Fedorowski A, Stewart J, Gibbons C, Sutton R, Shen WK, Muldowney J, Chung TH, Feigofsky S, Nayak H, Calkins H, Benditt DG. Postural Orthostatic Tachycardia Syndrome (POTS): A critical assessment. Prog Cardiovasc Dis. 2020 May - Jun; 63(3):263-270. PMID: 32222376.
    Citations: 4     Fields:    Translation:Humans
  13. Gibbons CH. Treatment induced neuropathy of diabetes. Auton Neurosci. 2020 07; 226:102668. PMID: 32247944.
    Citations: 2     Fields:    
  14. Gibbons CH, Wang N, Kim JY, Campagnolo M, Freeman R. Skin Biopsy in Evaluation of Autonomic Disorders. Continuum (Minneap Minn). 2020 Feb; 26(1):200-212. PMID: 31996629.
    Citations: 1     Fields:    Translation:Humans
  15. Barboi A, Gibbons CH, Axelrod F, Benarroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR. Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society. Auton Neurosci. 2020 01; 223:102550. PMID: 31928708.
    Citations: 2     Fields:    Translation:Humans
  16. Barboi A, Gibbons CH, Bennaroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR. Response to: Human papillomavirus (HPV) vaccine safety concerning POTS, CRPS and related conditions. Clin Auton Res. 2020 04; 30(2):183-184. PMID: 31802304.
    Citations:    Fields:    Translation:HumansCells
  17. Isonaka R, Gibbons CH, Wang N, Freeman R, Goldstein DS. Association of innervation-adjusted alpha-synuclein in arrector pili muscles with cardiac noradrenergic deficiency in autonomic synucleinopathies. Clin Auton Res. 2019 12; 29(6):587-593. PMID: 31673840.
    Citations: 2     Fields:    Translation:HumansCells
  18. Barboi A, Gibbons CH, Axelrod F, Benarroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR. Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society. Clin Auton Res. 2020 02; 30(1):13-18. PMID: 31475305.
    Citations: 3     Fields:    
  19. Gewandter JS, Gibbons CH, Campagnolo M, Lee J, Chaudari J, Ward N, Burke L, Cavaletti G, Herrmann DN, McArthur JC, Russell JW, Smith AG, Smith SM, Turk DC, Dworkin RH, Freeman R. Clinician-rated measures for distal symmetrical axonal polyneuropathy: ACTTION systematic review. Neurology. 2019 08 20; 93(8):346-360. PMID: 31320471.
    Citations: 3     Fields:    Translation:Humans
  20. Kim JY, Illigens BM, McCormick MP, Wang N, Gibbons CH. Alpha-Synuclein in Skin Nerve Fibers as a Biomarker for Alpha-Synucleinopathies. J Clin Neurol. 2019 Apr; 15(2):135-142. PMID: 30938106.
    Citations: 6     
  21. Thomas S, Ajroud-Driss S, Dimachkie MM, Gibbons C, Freeman R, Simpson DM, Singleton JR, Smith AG, Höke A. Peripheral Neuropathy Research Registry: A prospective cohort. J Peripher Nerv Syst. 2019 03; 24(1):39-47. PMID: 30629307.
    Citations: 1     Fields:    Translation:Humans
  22. Gibbons CH. Basics of autonomic nervous system function. Handb Clin Neurol. 2019; 160:407-418. PMID: 31277865.
    Citations: 4     Fields:    Translation:HumansAnimals
  23. Illigens BMW, Gibbons CH. Autonomic testing, methods and techniques. Handb Clin Neurol. 2019; 160:419-433. PMID: 31277866.
    Citations: 3     Fields:    Translation:Humans
  24. González-Duarte A, Cárdenas-Soto K, Fueyo O, Bañuelos CE, Gibbons C, Freeman R. Small fibre neuropathy assessments in early stages of hATTR amyloidosis. Amyloid. 2019; 26(sup1):55-56. PMID: 31343296.
    Citations:    Fields:    Translation:Humans
  25. Evans JP, Smith A, Gibbons C, Alonso J, Valderas JM. The National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS): a view from the UK. Patient Relat Outcome Meas. 2018; 9:345-352. PMID: 30498382.
    Citations: 7     
  26. Freeman R, Abuzinadah AR, Gibbons C, Jones P, Miglis MG, Sinn DI. Orthostatic Hypotension: JACC State-of-the-Art Review. J Am Coll Cardiol. 2018 09 11; 72(11):1294-1309. PMID: 30190008.
    Citations: 20     Fields:    Translation:Humans
  27. Claassen DO, Adler CH, Hewitt LA, Gibbons C. Characterization of the symptoms of neurogenic orthostatic hypotension and their impact from a survey of patients and caregivers. BMC Neurol. 2018 Aug 25; 18(1):125. PMID: 30144800.
    Citations: 10     Fields:    Translation:Humans
  28. Rajan S, Campagnolo M, Callaghan B, Gibbons CH. Sudomotor function testing by electrochemical skin conductance: does it really measure sudomotor function? Clin Auton Res. 2019 02; 29(1):31-39. PMID: 29956008.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  29. Provitera V, Gibbons CH, Wendelschafer-Crabb G, Donadio V, Vitale DF, Loavenbruck A, Stancanelli A, Caporaso G, Liguori R, Wang N, Santoro L, Kennedy WR, Nolano M. The role of skin biopsy in differentiating small-fiber neuropathy from ganglionopathy. Eur J Neurol. 2018 06; 25(6):848-853. PMID: 29493845.
    Citations: 2     Fields:    Translation:HumansCells
  30. Norcliffe-Kaufmann L, Kaufmann H, Palma JA, Shibao CA, Biaggioni I, Peltier AC, Singer W, Low PA, Goldstein DS, Gibbons CH, Freeman R, Robertson D. Orthostatic heart rate changes in patients with autonomic failure caused by neurodegenerative synucleinopathies. Ann Neurol. 2018 03; 83(3):522-531. PMID: 29405350.
    Citations: 27     Fields:    Translation:Humans
  31. Centi J, Freeman R, Gibbons CH, Neargarder S, Canova AO, Cronin-Golomb A. Author response: Effects of orthostatic hypotension on cognition in Parkinson disease. Neurology. 2017 11 14; 89(20):2122. PMID: 29133613.
    Citations:    Fields:    Translation:Humans
  32. Gibbons CH. Treatment-Induced Neuropathy of Diabetes. Curr Diab Rep. 2017 Oct 24; 17(12):127. PMID: 29064042.
    Citations: 9     Fields:    Translation:Humans
  33. Gibbons CH, Goebel-Fabbri A. Microvascular Complications Associated With Rapid Improvements in Glycemic Control in Diabetes. Curr Diab Rep. 2017 07; 17(7):48. PMID: 28526993.
    Citations: 2     Fields:    Translation:Humans
  34. Gibbons CH, Simon DK, Huang M, Tilley B, Aminoff MJ, Bainbridge JL, Brodsky M, Freeman R, Goudreau J, Hamill RW, Luo ST, Singer C, Videnovic A, Bodis-Wollner I, Wong PS. Autonomic and electrocardiographic findings in Parkinson's disease. Auton Neurosci. 2017 07; 205:93-98. PMID: 28506500.
    Citations: 2     Fields:    Translation:Humans
  35. Kaufmann H, Norcliffe-Kaufmann L, Palma JA, Biaggioni I, Low PA, Singer W, Goldstein DS, Peltier AC, Shibao CA, Gibbons CH, Freeman R, Robertson D. Natural history of pure autonomic failure: A United States prospective cohort. Ann Neurol. 2017 Feb; 81(2):287-297. PMID: 28093795.
    Citations: 61     Fields:    Translation:Humans
  36. Gibbons CH. Treatment induced neuropathy of diabetes-Long term implications in type 1 diabetes. J Diabetes Complications. 2017 Apr; 31(4):715-720. PMID: 28159476.
    Citations: 5     Fields:    Translation:Humans
  37. Gibbons CH, Schmidt P, Biaggioni I, Frazier-Mills C, Freeman R, Isaacson S, Karabin B, Kuritzky L, Lew M, Low P, Mehdirad A, Raj SR, Vernino S, Kaufmann H. The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension. J Neurol. 2017 Aug; 264(8):1567-1582. PMID: 28050656.
    Citations: 60     Fields:    Translation:Humans
  38. Gibbons CH, Wang N, Freeman R. Cutaneous Alpha-Synuclein From Paraffin Embedded Autopsy Specimens in Parkinson's Disease. J Parkinsons Dis. 2017; 7(3):503-509. PMID: 28582870.
    Citations: 4     Fields:    Translation:HumansCells
  39. Gewandter JS, Burke L, Cavaletti G, Dworkin RH, Gibbons C, Gover TD, Herrmann DN, Mcarthur JC, McDermott MP, Rappaport BA, Reeve BB, Russell JW, Smith AG, Smith SM, Turk DC, Vinik AI, Freeman R. Content validity of symptom-based measures for diabetic, chemotherapy, and HIV peripheral neuropathy. Muscle Nerve. 2017 03; 55(3):366-372. PMID: 27447116.
    Citations: 5     Fields:    Translation:Humans
  40. Centi J, Freeman R, Gibbons CH, Neargarder S, Canova AO, Cronin-Golomb A. Effects of orthostatic hypotension on cognition in Parkinson disease. Neurology. 2017 Jan 03; 88(1):17-24. PMID: 27903817.
    Citations: 20     Fields:    Translation:Humans
  41. Abuzinadah AR, Sinn DI, Freeman R, Gibbons CH. Blood pressure oscillations in baroreflex failure. Clin Auton Res. 2016 12; 26(6):465-466. PMID: 27541037.
    Citations: 1     Fields:    Translation:Humans
  42. Gibbons CH, Garcia J, Wang N, Shih LC, Freeman R. The diagnostic discrimination of cutaneous a-synuclein deposition in Parkinson disease. Neurology. 2016 Aug 02; 87(5):505-12. PMID: 27385742.
    Citations: 23     Fields:    Translation:Humans
  43. Sinn DI, Gibbons CH. Pathophysiology and Treatment of Orthostatic Hypotension in Parkinsonian Disorders. Curr Treat Options Neurol. 2016 Jun; 18(6):28. PMID: 27138287.
    Citations: 1     
  44. Provitera V, Gibbons CH, Wendelschafer-Crabb G, Donadio V, Vitale DF, Stancanelli A, Caporaso G, Liguori R, Wang N, Santoro L, Kennedy WR, Nolano M. A multi-center, multinational age- and gender-adjusted normative dataset for immunofluorescent intraepidermal nerve fiber density at the distal leg. Eur J Neurol. 2016 Feb; 23(2):333-8. PMID: 26493160.
    Citations: 18     Fields:    Translation:HumansCells
  45. Fedorowski A, Gibbons C. Orthostatic hypotension and diabetes are dangerous companions. J Diabetes Complications. 2016 Jan-Feb; 30(1):5-6. PMID: 26601788.
    Citations: 3     Fields:    Translation:Humans
  46. Gibbons CH, Freeman R. Clinical implications of delayed orthostatic hypotension: A 10-year follow-up study. Neurology. 2015 Oct 20; 85(16):1362-7. PMID: 26400576.
    Citations: 30     Fields:    Translation:Humans
  47. Jones PK, Gibbons CH. Autonomic function testing: an important diagnostic test for patients with syncope. Pract Neurol. 2015 Oct; 15(5):346-51. PMID: 26109586.
    Citations: 1     Fields:    Translation:Humans
  48. Gibbons C. Postural tachycardia syndrome, the debate continues…. Clin Auton Res. 2014 Dec; 24(6):245-6. PMID: 25391988.
    Citations:    Fields:    Translation:Humans
  49. Gibbons CH, Freeman R. Treatment-induced neuropathy of diabetes: an acute, iatrogenic complication of diabetes. Brain. 2015 Jan; 138(Pt 1):43-52. PMID: 25392197.
    Citations: 30     Fields:    Translation:Humans
  50. Gibbons CH. Small fiber neuropathies. Continuum (Minneap Minn). 2014 Oct; 20(5 Peripheral Nervous System Disorders):1398-412. PMID: 25299289.
    Citations: 6     Fields:    Translation:Humans
  51. Jones PK, Gibbons CH. The role of autonomic testing in syncope. Auton Neurosci. 2014 Sep; 184:40-5. PMID: 24948113.
    Citations: 3     Fields:    Translation:Humans
  52. Gibbons CH, Bonyhay I, Benson A, Wang N, Freeman R. Structural and functional small fiber abnormalities in the neuropathic postural tachycardia syndrome. PLoS One. 2013; 8(12):e84716. PMID: 24386408.
    Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
  53. Gibbons C, Cheshire W, Barboi A, Levine B, Olshansky B, Kinsella L, Claydon VE, Crandall C, Fink G, Joyner M, Macefield V, Norcliffe-Kaufmann L, Freeman R, Raj S, Stewart J, Sandroni P, Kaufmann H, Chelimsky T. Endovascular procedures for the treatment of autonomic dysfunction. Clin Auton Res. 2014 Feb; 24(1):1-2. PMID: 24178965.
    Citations:    Fields:    Translation:Humans
  54. Wang N, Gibbons CH, Lafo J, Freeman R. a-Synuclein in cutaneous autonomic nerves. Neurology. 2013 Oct 29; 81(18):1604-10. PMID: 24089386.
    Citations: 67     Fields:    Translation:HumansCells
  55. Boruchow SA, Gibbons CH. Utility of skin biopsy in management of small fiber neuropathy. Muscle Nerve. 2013 Dec; 48(6):877-82. PMID: 23553795.
    Citations: 3     Fields:    Translation:Humans
  56. Illigens BM, Siepmann T, Roofeh J, Gibbons CH. Laser Doppler imaging in the detection of peripheral neuropathy. Auton Neurosci. 2013 Oct; 177(2):286-90. PMID: 23850386.
    Citations: 11     Fields:    Translation:Humans
  57. Gibbons CH, Freeman R, Tecilazich F, Dinh T, Lyons TE, Gnardellis C, Veves A. The evolving natural history of neurophysiologic function in patients with well-controlled diabetes. J Peripher Nerv Syst. 2013 Jun; 18(2):153-61. PMID: 23781962.
    Citations: 5     Fields:    Translation:Humans
  58. Illigens BM, Gibbons CH. A human model of small fiber neuropathy to study wound healing. PLoS One. 2013; 8(1):e54760. PMID: 23382960.
    Citations: 6     Fields:    Translation:HumansCells
  59. Wang N, Gibbons CH. Skin biopsies in the assessment of the autonomic nervous system. Handb Clin Neurol. 2013; 117:371-8. PMID: 24095140.
    Citations: 7     Fields:    Translation:HumansAnimals
  60. Siepmann T, Gibbons CH, Illigens BM, Lafo JA, Brown CM, Freeman R. Quantitative pilomotor axon reflex test: a novel test of pilomotor function. Arch Neurol. 2012 Nov; 69(11):1488-92. PMID: 22868966.
    Citations: 8     Fields:    Translation:HumansCells
  61. Gibbons CH, Adler GK, Bonyhay I, Freeman R. Experimental hypoglycemia is a human model of stress-induced hyperalgesia. Pain. 2012 Nov; 153(11):2204-2209. PMID: 22921261.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  62. Muppidi S, Scribner M, Gibbons CH, Adams-Huet B, Spaeth EB, Vernino S. A Unique Manifestation of Pupillary Fatigue in Autoimmune Autonomic Ganglionopathy. Arch Neurol. 2012 May; 69(5):644-8. PMID: 22232207.
    Citations: 4     Fields:    Translation:Humans
  63. Gibbons CH, Centi J, Vernino S, Freeman R. Autoimmune autonomic ganglionopathy with reversible cognitive impairment. Arch Neurol. 2012 Apr; 69(4):461-6. PMID: 22158721.
    Citations: 11     Fields:    Translation:Humans
  64. Hovaguimian A, Gibbons CH. Diagnosis and treatment of pain in small-fiber neuropathy. Curr Pain Headache Rep. 2011 Jun; 15(3):193-200. PMID: 21286866.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  65. Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz I, Schondorff R, Stewart JM, van Dijk JG. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res. 2011 Apr; 21(2):69-72. PMID: 21431947.
    Citations: 329     Fields:    Translation:Humans
  66. Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz IJ, Schondorf R, Stewart JM, van Dijk JG. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Auton Neurosci. 2011 Apr 26; 161(1-2):46-8. PMID: 21393070.
    Citations: 85     Fields:    Translation:Humans
  67. Hovaguimian A, Gibbons CH. Clinical Approach to the Treatment of Painful Diabetic Neuropathy. Ther Adv Endocrinol Metab. 2011 Feb; 2(1):27-38. PMID: 21709806.
    Citations: 8     
  68. Wang N, Gibbons CH, Freeman R. Novel immunohistochemical techniques using discrete signal amplification systems for human cutaneous peripheral nerve fiber imaging. J Histochem Cytochem. 2011 Apr; 59(4):382-90. PMID: 21411809.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  69. Gibbons CH, Wang N, Freeman R. Capsaicin induces degeneration of cutaneous autonomic nerve fibers. Ann Neurol. 2010 Dec; 68(6):888-98. PMID: 21061393.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  70. Gibbons CH, Freeman R, Veves A. Diabetic neuropathy: a cross-sectional study of the relationships among tests of neurophysiology. Diabetes Care. 2010 Dec; 33(12):2629-34. PMID: 20805259.
    Citations: 16     Fields:    Translation:Humans
  71. Gibbons CH, Illigens BM, Wang N, Freeman R. Quantification of sudomotor innervation: a comparison of three methods. Muscle Nerve. 2010 Jul; 42(1):112-9. PMID: 20544913.
    Citations: 13     Fields:    Translation:HumansCells
  72. Gibbons CH, Freeman R. Treatment-induced diabetic neuropathy: a reversible painful autonomic neuropathy. Ann Neurol. 2010 Apr; 67(4):534-41. PMID: 20437589.
    Citations: 41     Fields:    Translation:HumansCells
  73. Kasselman LJ, Veves A, Gibbons CH, Rutkove SB. Cold exposure exacerbates the development of diabetic polyneuropathy in the rat. Exp Diabetes Res. 2009; 2009:827943. PMID: 20130819.
    Citations: 2     Fields:    Translation:AnimalsCells
  74. Gibbons CH, Illigens BM, Wang N, Freeman R. Quantification of sweat gland innervation: a clinical-pathologic correlation. Neurology. 2009 Apr 28; 72(17):1479-86. PMID: 19398703.
    Citations: 37     Fields:    Translation:HumansCells
  75. Gibbons CH, Freeman R. Antibody titers predict clinical features of autoimmune autonomic ganglionopathy. Auton Neurosci. 2009 Mar 12; 146(1-2):8-12. PMID: 19144572.
    Citations: 19     Fields:    Translation:Humans
  76. Illigens BM, Gibbons CH. Sweat testing to evaluate autonomic function. Clin Auton Res. 2009 Apr; 19(2):79-87. PMID: 18989618.
    Citations: 34     Fields:    Translation:Humans
  77. Lair L, Gibbons C, Freeman R. Phantom sweating: a novel autonomic paresthesia. Clin Auton Res. 2008 Dec; 18(6):352-4. PMID: 18850064.
    Citations:    Fields:    Translation:Humans
  78. Gibbons CH, Illigens BM, Centi J, Freeman R. QDIRT: quantitative direct and indirect test of sudomotor function. Neurology. 2008 Jun 10; 70(24):2299-304. PMID: 18541883.
    Citations: 17     Fields:    Translation:HumansCells
  79. Gibbons CH, Vernino SA, Freeman R. Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy. Arch Neurol. 2008 Feb; 65(2):213-7. PMID: 18268189.
    Citations: 19     Fields:    Translation:Humans
  80. Ebenezer GJ, Hauer P, Gibbons C, McArthur JC, Polydefkis M. Assessment of epidermal nerve fibers: a new diagnostic and predictive tool for peripheral neuropathies. J Neuropathol Exp Neurol. 2007 Dec; 66(12):1059-73. PMID: 18090915.
    Citations: 33     Fields:    Translation:HumansCells
  81. Christopher Gibbons, Ningshan Wang, Ben Illigens, Justin Centi, Roy Freeman. The Cutaneous Architecture of Autonomic Nerve Fiber Innervation. Clinical Autonomic Research. 2007; 17(5):319.
  82. Christopher Gibbons, Justin Centi, Anh Thu Nguyen, Roy Freeman. Peripheral Autonomic Dysfunction Precedes Structural Abnormalities in Diabetic Small Fiber Neuropathy. Clinical Autonomic Research. 2007; 17(5):306.
  83. Wang Z, Low PA, Jordan J, Freeman R, Gibbons CH, Schroeder C, Sandroni P, Vernino S. Autoimmune autonomic ganglionopathy: IgG effects on ganglionic acetylcholine receptor current. Neurology. 2007 May 29; 68(22):1917-21. PMID: 17536048.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  84. Gibbons C, Illigens B, Centi J, Freeman R. Modeling the Role of Peripheral Neuropathy on Wound Healing. Neurology. 2007.
  85. Gibbons CH, Freeman R. Delayed orthostatic hypotension: a frequent cause of orthostatic intolerance. Neurology. 2006 Jul 11; 67(1):28-32. PMID: 16832073.
    Citations: 55     Fields:    Translation:Humans
  86. Gibbons C, Centi J, DeZure A, Freeman R. A Capsaicin Model of Autonomic Nerve Fiber Degeneration and Regeneration. Neurology. 2006; 66(5 S2):A258-9.
  87. Gibbons CH, Freeman R. Treatment options for autonomic neuropathies. Curr Treat Options Neurol. 2006 Mar; 8(2):119-32. PMID: 16464408.
    Citations: 3     
  88. Gibbons CH, Griffin JW, Polydefkis M, Bonyhay I, Brown A, Hauer PE, McArthur JC. The utility of skin biopsy for prediction of progression in suspected small fiber neuropathy. Neurology. 2006 Jan 24; 66(2):256-8. PMID: 16434668.
    Citations: 36     Fields:    Translation:HumansCells
  89. Freeman R, Gibbons C. Is time of the essence? The continuing search for a noninvasive measure of sympathetic adrenergic function. Neurology. 2005 Nov 22; 65(10):1517. PMID: 16304717.
    Citations:    Fields:    Translation:HumansCells
  90. Gibbons CH, Vernino SA, Kaufmann H, Freeman R. L-DOPS therapy for refractory orthostatic hypotension in autoimmune autonomic neuropathy. Neurology. 2005 Oct 11; 65(7):1104-6. PMID: 16217067.
    Citations: 7     Fields:    Translation:Humans
  91. Gibbons CH, Freeman R. Autonomic neuropathy and coeliac disease. J Neurol Neurosurg Psychiatry. 2005 Apr; 76(4):579-81. PMID: 15774451.
    Citations: 8     Fields:    Translation:Humans
  92. Gibbons CH, Freeman R. Orthostatic dyspnea: a neglected symptom of orthostatic hypotension. Clin Auton Res. 2005 Feb; 15(1):40-4. PMID: 15768201.
    Citations: 12     Fields:    Translation:Humans
  93. Gibbons C, Freeman R. The evaluation of small fiber function-autonomic and quantitative sensory testing. Neurol Clin. 2004 Aug; 22(3):683-702, vii. PMID: 15207880.
    Citations: 10     Fields:    Translation:HumansCells
  94. Gibbons C, Llinas R. Case 1: a woman with headache and dizziness. MedGenMed. 2003 Feb 13; 5(1):35. PMID: 12827096.
    Citations:    Fields:    Translation:Humans
  95. Gibbons CH, McArthur JC. Case 8: A Young Man With Painful Inability To Walk. MedGenMed. 2002.
  96. Gibbons C, Kollmann TR, Pettoello-Mantovani M, Kim A, Goldstein H. Thy/Liv-SCID-Hu mice implanted with human intestine: an in vivo model for investigation of mucosal transmission of HIV. AIDS Res Hum Retroviruses. 1997 Nov 20; 13(17):1453-60. PMID: 9390744.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  97. Clark AS, Lindenfeld RC, Gibbons CH. Anabolic-androgenic steroids and brain reward. Pharmacol Biochem Behav. 1996 Mar; 53(3):741-5. PMID: 8866980.
    Citations: 12     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.