Teresa Chia-Ching Chen, M.D.
Associate Professor of Ophthalmology
Massachusetts Eye and Ear Infirmary
Massachusetts Eye & Ear Infrm
c/o Faculty Services, 8th FL
243 Charles St
Boston MA 02114
Available: 08/07/17, Expires: 06/27/22
Start dates are flexible. The goal of this experience is for the student to learn the basics of clinical translational research and to participate in paper publications. The topic of the research is 3D imaging of the eye with either spectral domain optical coherence tomography (OCT) imaging or swept source imaging, with spectral domain OCT being perhaps the fastest growing 3-dimensional ophthalmic imaging modality of the past decade. Although the first ultra-high speed ultra-high resolution spectral domain OCT images were obtained by this group’s prototype spectral domain OCT machine (developed by Johannes de Boer, PhD and MGH Wellman colleagues), current research focuses on the current commercially available spectral domain and swept source OCT machines housed at the Massachusetts Eye and Ear Infirmary. The long-term goal of this translational research aims to bring this exciting bench research discovery into mainstream clinical practice for the benefit of our glaucoma patients. The hope is that the student will learn about the basics of clinical studies (i.e. patient recruitment, data analysis, etc.). The student will primarily assist in data collection, data downloading and maintenance, and data analysis. If the student is available for a few months, a middle authorship may be achieved. If the student is available for a few months to a year, he/she would have an opportunity to write a first author paper, time-permitting. An existing database of almost 2,000 patient eye images provide plenty of data for research projects. Although 4-6 months is ideal, shorter or longer research periods are available, depending on what the student wishes to accomplish.
Available: 08/07/17, Expires: 08/07/22
The Massachusetts Eye and Ear Infirmary has one of the largest databases of ultra-high resolution three-dimensional images of the eye using spectral domain optical coherence tomography. This 5 year prospective database has almost 2,000 patients, which provide plenty of data for a research paper. If a medical student were to spend a summer helping with data collection and analysis, this may be a reasonable amount of time for a middle authorship position. If the medical student were to spend more than a summer for data analysis and paper writing, a first author paper would be possible. Time commitment is flexible, ranging from a summer to an entire research year.
Available: 08/07/17, Expires: 08/06/22
The Massachusetts Eye and Ear Infirmary has one of the largest databases of ultra-high resolution three-dimensional (3D) images of the eye. This 5 year prospective database has almost 2,000 patients, which provide plenty of data for an aspiring student to achieve a middle authorship or first authorship paper, depending on the student's available time and motivation. This imaging database features 3D scans of the eye, using spectral domain optical coherence tomography, the most common 3D imaging modality used by ophthalmologists today. Projects may also utilize swept source optical coherence tomography, a newer faster 3D imaging modality which enables deeper tissue penetration.
Projects can be catered to the student's time, availability, schedule, and interests. In summary, research projects may involve "all things imaging" in ophthalmology: translational research, clinical care improvements, telemedicine, and artificial intelligence.
Evaluation of artifacts associated with retinal nerve fiber layer imaging using spectral-domain optical coherence tomography in glaucoma patients
Summer, 07/01/13 - 08/15/13
Evaluating the frequency of artifacts in spectral-domain images of the retina and optic nerve
Summer, 06/06/14 - 08/18/14
Correlation of 3D Neuroretinal Rim Thickness and Visual Fields in Glaucoma: A Broken Stick Model
Summer, 06/05/15 - 08/28/15
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