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profileAlexa T. McCray, Ph.D.

TitleProfessor of Medicine
InstitutionBeth Israel Deaconess Medical Center
DepartmentMedicine
AddressHarvard Medical School
Department of Biomedical Informatics
10 Shattuck St
Boston MA 02115
Phone617/432-2144
Fax617/432-0693
vCardDownload vCard (login for email)
Other Positions
TitleDirector, Informatics Training Program
InstitutionHarvard Medical School
DepartmentBiomedical Informatics


Collapse Mentoring 
Collapse completed student projects
The Readability of Online Consumer Health Information: a Meta-Analysis
Summer, 04/02/12 - 08/31/12

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
U01HG007530     (KOHANE, ISAAC S.)Dec 20, 2013 - Nov 30, 2017
NIH/NHGRI
Coordinating Center for the Undiagnosed Diseases Network
Role: Co-Principal Investigator

T15LM007092     (MCCRAY, ALEXA T.)Jul 1, 1992 - Jun 30, 2022
NIH/NLM
Biomedical Informatics and Data Science Research Training Program (BIRT)
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Haux R, Geissbuhler A, Holmes J, Jaulent MC, Koch S, Kulikowski CA, Lehmann CU, McCray AT, Séroussi B, Soualmia LF, van Bemmel JH. On Contributing to the Progress of Medical Informatics as Publisher. Congratulations to IMIA Honorary Fellow Dieter Bergemann on his 80th Birthday! Yearb Med Inform. 2017 May 08; 26(1). PMID: 28480470.
    View in: PubMed
  2. Ramoni RB, Mulvihill JJ, Adams DR, Allard P, Ashley EA, Bernstein JA, Gahl WA, Hamid R, Loscalzo J, McCray AT, Shashi V, Tifft CJ, Wise AL. The Undiagnosed Diseases Network: Accelerating Discovery about Health and Disease. Am J Hum Genet. 2017 Feb 02; 100(2):185-192. PMID: 28157539.
    View in: PubMed
  3. Haux R, Kulikowski CA, Bakken S, de Lusignan S, Kimura M, Koch S, Mantas J, Maojo V, Marschollek M, Martin-Sanchez F, Moen A, Park HA, Sarkar IN, Leong TY, McCray AT. Research Strategies for Biomedical and Health Informatics. Some Thought-provoking and Critical Proposals to Encourage Scientific Debate on the Nature of Good Research in Medical Informatics. Methods Inf Med. 2017 Jan 25; 56(Open):e1-e10. PMID: 28119991.
    View in: PubMed
  4. van Bemmel JH, McCray AT. The Renewed Promise of Medical Informatics. Yearb Med Inform. 2016 May 20; Suppl 1:S12-7. PMID: 27199195.
    View in: PubMed
  5. McCray AT, Glaser J, Koppel R, Langlotz CP, Silverstein J. Health IT vendors and the academic community: The 2014 ACMI debate. J Biomed Inform. 2016 Apr; 60:365-75. PMID: 26968349.
    View in: PubMed
  6. Antman EM, Benjamin EJ, Harrington RA, Houser SR, Peterson ED, Bauman MA, Brown N, Bufalino V, Califf RM, Creager MA, Daugherty A, Demets DL, Dennis BP, Ebadollahi S, Jessup M, Lauer MS, Lo B, MacRae CA, McConnell MV, McCray AT, Mello MM, Mueller E, Newburger JW, Okun S, Packer M, Philippakis A, Ping P, Prasoon P, Roger VL, Singer S, Temple R, Turner MB, Vigilante K, Warner J, Wayte P. Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015. J Am Heart Assoc. 2015 Nov 05; 4(11). PMID: 26541391; PMCID: PMC4845234.
  7. Taruscio D, Groft SC, Cederroth H, Melegh B, Lasko P, Kosaki K, Baynam G, McCray A, Gahl WA. Undiagnosed Diseases Network International (UDNI): White paper for global actions to meet patient needs. Mol Genet Metab. 2015 Dec; 116(4):223-5. PMID: 26596705.
    View in: PubMed
  8. McCray AT, Trevvett P, Frost HR. Modeling the autism spectrum disorder phenotype. Neuroinformatics. 2014 Apr; 12(2):291-305. PMID: 24163114; PMCID: PMC4000751.
  9. Rosenfeld L, Shepherd A, Agunwamba AA, McCray AT. Iterative evaluation of a web-based health information resource. J Health Commun. 2013 Aug; 18(8):974-90. PMID: 23577665; PMCID: PMC3711962.
  10. Durant KT, McCray AT, Safran C. Identifying gender-preferred communication styles within online cancer communities: a retrospective, longitudinal analysis. PLoS One. 2012; 7(11):e49169. PMID: 23155460; PMCID: PMC3498295.
  11. Frost HR, McCray AT. Markov Chain Ontology Analysis (MCOA). BMC Bioinformatics. 2012 Feb 03; 13:23. PMID: 22300537; PMCID: PMC3329418.
  12. Durant KT, McCray AT, Safran C. Identifying Temporal Changes and Topics that Promote Growth Within Online Communities: A Prospective Study of Six Online Cancer Forums. Int J Comput Models Algorithms Med. 2011 Apr; 2(2):1-22. PMID: 22022636.
    View in: PubMed
  13. McCray AT, Gefeller O, Aronsky D, Leong TY, Sarkar IN, Bergemann D, Lindberg DA, van Bemmel JH, Haux R. The birth and evolution of a discipline devoted to information in biomedicine and health care. As reflected in its longest running journal. Methods Inf Med. 2011; 50(6):491-507. PMID: 22146913.
    View in: PubMed
  14. Bellazzi R, Diomidous M, Sarkar IN, Takabayashi K, Ziegler A, McCray AT. Data analysis and data mining: current issues in biomedical informatics. Methods Inf Med. 2011; 50(6):536-44. PMID: 22146916; PMCID: PMC3233983.
  15. Haux R, Aronsky D, Leong TY, McCray AT. Methods in year 50: preserving the past and preparing for the future. Methods Inf Med. 2011; 50(1):1-6. PMID: 21229185.
    View in: PubMed
  16. Durant KT, McCray AT, Safran C. Social network analysis of an online melanoma discussion group. AMIA Jt Summits Transl Sci Proc. 2010 Mar 01; 2010:6-10. PMID: 21347134; PMCID: PMC3041535.
  17. Haux R, Aronsky D, Leong TY, McCray AT. Methods extends free access to papers and offers optional open access model: new services and opportunities for authors and readers . Methods Inf Med. 2010; 49(1):1-2. PMID: 20062945.
    View in: PubMed
  18. Vizenor LT, Bodenreider O, McCray AT. Auditing associative relations across two knowledge sources. J Biomed Inform. 2009 Jun; 42(3):426-39. PMID: 19475724; PMCID: PMC2891883.
  19. McMurry A, Cervone M, Polumbo G, McCray AT. Correlating phenotype and genotype in autism spectrum disorder research. AMIA Annu Symp Proc. 2008 Nov 06; 894. PMID: 18998837.
    View in: PubMed
  20. Aronsky D, Haux R, Leong TY, McCray A. The Student Editorial Board of Methods of Information in Medicine--an opportunity to educate tomorrow's peer reviewers. Methods Inf Med. 2007; 46(6):623-4. PMID: 18066409.
    View in: PubMed
  21. Miller RA, Groth T, Hasman A, Haux R, McCray AT, Safran C, Shortliffe EH. On exemplary scientific conduct regarding submission of manuscripts to biomedical informatics journals. Comput Methods Programs Biomed. 2006 Mar; 81(3):195-6. PMID: 16503365.
    View in: PubMed
  22. Hasman A, Bergemann D, McCray AT, Talmon JL, Zvárová J. Triangulation applied to Jan H. van Bemmel. Methods Inf Med. 2006; 45(6):656-67. PMID: 17149508.
    View in: PubMed
  23. Vizenor L, Bodenreider O, Peters L, McCray AT. Enhancing biomedical ontologies through alignment of semantic relationships: exploratory approaches. AMIA Annu Symp Proc. 2006; 804-8. PMID: 17238452; PMCID: PMC1839588.
  24. Miller RA, Groth T, Hasman A, Safran C, Shortliffe EH, Haux R, McCray AT. On exemplary scientific conduct regarding submission of manuscripts to biomedical informatics journals. Methods Inf Med. 2006; 45(1):1-3. PMID: 16482363.
    View in: PubMed
  25. Fomous C, Mitchell JA, McCray A. 'Genetics home reference': helping patients understand the role of genetics in health and disease. Community Genet. 2006; 9(4):274-8. PMID: 17003538.
    View in: PubMed
  26. McCray AT. Conceptualizing the world: lessons from history. J Biomed Inform. 2006 Jun; 39(3):267-73. PMID: 16243005.
    View in: PubMed
  27. Bodenreider O, Mitchell JA, McCray AT. Biomedical ontologies. Pac Symp Biocomput. 2005; 76-8. PMID: 15759615; PMCID: PMC4300097.
  28. McCray AT. Promoting health literacy. J Am Med Inform Assoc. 2005 Mar-Apr; 12(2):152-63. PMID: 15561782; PMCID: PMC551547.
  29. Mitchell JA, Fun J, McCray AT. Design of Genetics Home Reference: a new NLM consumer health resource. J Am Med Inform Assoc. 2004 Nov-Dec; 11(6):439-47. PMID: 15298997; PMCID: PMC524623.
  30. McCray AT, Ide NC, Loane RR, Tse T. Strategies for supporting consumer health information seeking. Stud Health Technol Inform. 2004; 107(Pt 2):1152-6. PMID: 15360993.
    View in: PubMed
  31. Gillen JE, Tse T, Ide NC, McCray AT. Design, implementation and management of a web-based data entry system for ClinicalTrials.gov. Stud Health Technol Inform. 2004; 107(Pt 2):1466-70. PMID: 15361058.
    View in: PubMed
  32. Lomax J, McCray AT. Mapping the gene ontology into the unified medical language system. Comp Funct Genomics. 2004; 5(4):354-61. PMID: 18629164; PMCID: PMC2447454.
  33. Bodenreider O, McCray AT. Exploring semantic groups through visual approaches. J Biomed Inform. 2003 Dec; 36(6):414-32. PMID: 14759816; PMCID: PMC1997308.
  34. Ammenwerth E, Wolff AC, Knaup P, Ulmer H, Skonetzki S, van Bemmel JH, McCray AT, Haux R, Kulikowski C. Developing and evaluating criteria to help reviewers of biomedical informatics manuscripts. J Am Med Inform Assoc. 2003 Sep-Oct; 10(5):512-4. PMID: 12807814; PMCID: PMC212789.
  35. Browne AC, Divita G, Aronson AR, McCray AT. UMLS language and vocabulary tools. AMIA Annu Symp Proc. 2003; 798. PMID: 14728303; PMCID: PMC1480270.
  36. McCray AT. Informatics Research, Development, and Training at the Lister Hill National Center for Biomedical Communications. Yearb Med Inform. 2003; (1):193-203. PMID: 27706338.
    View in: PubMed
  37. Mitchell JA, McCray AT. The Genetics Home Reference: a new NLM consumer health resource. AMIA Annu Symp Proc. 2003; 936. PMID: 14728441; PMCID: PMC1480143.
  38. McCray AT, Tse T. Understanding search failures in consumer health information systems. AMIA Annu Symp Proc. 2003; 430-4. PMID: 14728209; PMCID: PMC1479930.
  39. Mitchell JA, McCray AT, Bodenreider O. From phenotype to genotype: issues in navigating the available information resources. Methods Inf Med. 2003; 42(5):557-63. PMID: 14654891; PMCID: PMC1800828.
  40. McCray AT. An upper-level ontology for the biomedical domain. Comp Funct Genomics. 2003; 4(1):80-4. PMID: 18629109; PMCID: PMC2447396.
  41. Bodenreider O, Mitchell JA, McCray AT. Evaluation of the UMLS as a terminology and knowledge resource for biomedical informatics. Proc AMIA Symp. 2002; 61-5. PMID: 12463787; PMCID: PMC2244306.
  42. McCray AT, Haux R. Supporting open access to scientific information. Methods Inf Med. 2002; 41(4):243-4. PMID: 12425234.
    View in: PubMed
  43. McCray AT, Browne AC, Bodenreider O. The lexical properties of the gene ontology. Proc AMIA Symp. 2002; 504-8. PMID: 12463875; PMCID: PMC2244431.
  44. McCray AT, Burgun A, Bodenreider O. Aggregating UMLS semantic types for reducing conceptual complexity. Stud Health Technol Inform. 2001; 84(Pt 1):216-20. PMID: 11604736; PMCID: PMC4300099.
  45. McCray AT, Bodenreider O, Malley JD, Browne AC. Evaluating UMLS strings for natural language processing. Proc AMIA Symp. 2001; 448-52. PMID: 11825228; PMCID: PMC2243606.
  46. Haux R, McCray AT. Processing medical data, information and knowledge: new opportunities in the information society. Methods Inf Med. 2001; 40(4):272-4. PMID: 11552338.
    View in: PubMed
  47. McCray AT. Better access to information about clinical trials. Ann Intern Med. 2000 Oct 17; 133(8):609-14. PMID: 11033590.
    View in: PubMed
  48. McCray AT, Ide NC. Design and implementation of a national clinical trials registry. J Am Med Inform Assoc. 2000 May-Jun; 7(3):313-23. PMID: 10833169; PMCID: PMC61435.
  49. McCray AT. Improving access to healthcare information: the Lister Hill National Center for Biomedical Communications. MD Comput. 2000 Mar-Apr; 17(2):29-34. PMID: 10778296.
    View in: PubMed
  50. McCray AT, Dorfman E, Ripple A, Ide NC, Jha M, Katz DG, Loane RF, Tse T. Usability issues in developing a Web-based consumer health site. Proc AMIA Symp. 2000; 556-60. PMID: 11079945; PMCID: PMC2244083.
  51. McCray AT. Medical Informatics Research and Training at the Lister Hill National Center for Biomedical Communications. Yearb Med Inform. 2000; (1):95-99. PMID: 27699351.
    View in: PubMed
  52. McCray AT. Digital library research and application. Stud Health Technol Inform. 2000; 76:51-62. PMID: 10947501.
    View in: PubMed
  53. van Bemmel JH, McCray AT. Patient-centered Systems. Yearb Med Inform. 2000; (1):4-6. PMID: 27699346.
    View in: PubMed
  54. van Bemmel JH, McCray AT. The Promise of Medical Informatics. Yearb Med Inform. 1999; (1):3-5. PMID: 27699363.
    View in: PubMed
  55. McCray AT, Loane RF, Browne AC, Bangalore AK. Terminology issues in user access to Web-based medical information. Proc AMIA Symp. 1999; 107-11. PMID: 10566330; PMCID: PMC2232498.
  56. McCray AT. The nature of lexical knowledge. Methods Inf Med. 1998 Nov; 37(4-5):353-60. PMID: 9865033.
    View in: PubMed
  57. van Bemmel JH, McCray AT. Health Informatics and the Internet. Yearb Med Inform. 1998; (1):4-6. PMID: 27699330.
    View in: PubMed
  58. Bodenreider O, McCray AT. From French vocabulary to the Unified Medical Language System: a preliminary study. Stud Health Technol Inform. 1998; 52 Pt 1:670-4. PMID: 10384539; PMCID: PMC4296523.
  59. McCray AT, Browne AC. Discovering the modifiers in a terminology data set. Proc AMIA Symp. 1998; 780-4. PMID: 9929325; PMCID: PMC2232346.
  60. McCray AT, Miller RA. Making the conceptual connections: the Unified Medical Language System (UMLS) after a decade of research and development. J Am Med Inform Assoc. 1998 Jan-Feb; 5(1):129-30. PMID: 9471340; PMCID: PMC61282.
  61. Humphreys BL, McCray AT, Cheh ML. Evaluating the coverage of controlled health data terminologies: report on the results of the NLM/AHCPR large scale vocabulary test. J Am Med Inform Assoc. 1997 Nov-Dec; 4(6):484-500. PMID: 9391936; PMCID: PMC61267.
  62. McCray AT, van Bemmel JH. Computing and Collaborative Care. Yearb Med Inform. 1997; (1):4-5. PMID: 27699293.
    View in: PubMed
  63. McCray AT, Cheh ML, Bangalore AK, Rafei K, Razi AM, Divita G, Stavri PZ. Conducting the NLM/AHCPR Large Scale Vocabulary Test: a distributed Internet-based experiment. Proc AMIA Annu Fall Symp. 1997; 560-4. PMID: 9357688; PMCID: PMC2233508.
  64. Humphreys BL, Hole WT, McCray AT, Fitzmaurice JM. Planned NLM/AHCPR large-scale vocabulary test: using UMLS technology to determine the extent to which controlled vocabularies cover terminology needed for health care and public health. J Am Med Inform Assoc. 1996 Jul-Aug; 3(4):281-7. PMID: 8816351; PMCID: PMC116311.
  65. McCray AT, Razi AM, Bangalore AK, Browne AC, Stavri PZ. The UMLS Knowledge Source Server: a versatile Internet-based research tool. Proc AMIA Annu Fall Symp. 1996; 164-8. PMID: 8947649; PMCID: PMC2233094.
  66. van Bemmel JH, McCray AT. Integration of Information for Patient Care. Yearb Med Inform. 1996; (1):3-4. PMID: 27699309.
    View in: PubMed
  67. McCray AT, Scherrer JR, Safran C, Chute CG. Concepts, knowledge, and language in health-care information systems. Methods Inf Med. 1995 Mar; 34(1-2):1-4. PMID: 9082118.
    View in: PubMed
  68. McCray AT, Nelson SJ. The representation of meaning in the UMLS. Methods Inf Med. 1995 Mar; 34(1-2):193-201. PMID: 9082131.
    View in: PubMed
  69. McCray AT, Divita G. ASN.1: defining a grammar for the UMLS knowledge sources. Proc Annu Symp Comput Appl Med Care. 1995; 868-72. PMID: 8563416; PMCID: PMC2579217.
  70. McCray AT, Razi A. The UMLS Knowledge Source server. Medinfo. 1995; 8 Pt 1:144-7. PMID: 8591140.
    View in: PubMed
  71. van Bemmel JH, McCray AT. The Computer-based Patient Record. Yearb Med Inform. 1995; (1):3-4. PMID: 27668769.
    View in: PubMed
  72. van Bemmel JH, McCray AT. Advanced Communications in Health Care. Yearb Med Inform. 1994; (1):4-6. PMID: 27668611.
    View in: PubMed
  73. McCray AT, Srinivasan S, Browne AC. Lexical methods for managing variation in biomedical terminologies. Proc Annu Symp Comput Appl Med Care. 1994; 235-9. PMID: 7949926; PMCID: PMC2247735.
  74. Lindberg DA, Humphreys BL, McCray AT. The Unified Medical Language System. Methods Inf Med. 1993 Aug; 32(4):281-91. PMID: 8412823.
    View in: PubMed
  75. McCray AT, Aronson AR, Browne AC, Rindflesch TC, Razi A, Srinivasan S. UMLS knowledge for biomedical language processing. Bull Med Libr Assoc. 1993 Apr; 81(2):184-94. PMID: 8472004; PMCID: PMC225761.
  76. Lindberg DA, Humphreys BL, McCray AT. The Unified Medical Language System. Yearb Med Inform. 1993; (1):41-51. PMID: 27668467.
    View in: PubMed
  77. van Bemmel JH, McCray AT. Advances in an interdisciplinary science. Methods Inf Med. 1992 Nov; 31(4):235-46. PMID: 1470034.
    View in: PubMed
  78. van Bemmel JH, McCray AT. Advances in an Interdisciplinary Science. Yearb Med Inform. 1992; (1):9-12. PMID: 27668409.
    View in: PubMed
  79. van Bemmel JH, McCray AT. Synopsis of Scientific Contributions. Yearb Med Inform. 1992; (1):43-55. PMID: 27668410.
    View in: PubMed
  80. McCray AT. Extending a natural language parser with UMLS knowledge. Proc Annu Symp Comput Appl Med Care. 1991; 194-8. PMID: 1807586; PMCID: PMC2247522.
  81. McCray AT, Srinivasan S. Automated access to a large medical dictionary: online assistance for research and application in natural language processing. Comput Biomed Res. 1990 Apr; 23(2):179-98. PMID: 2185922.
    View in: PubMed
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