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Lakshmi Ganapathi, M.B.,B.S.

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Overview
I am a pediatric infectious diseases physician with clinical expertise in immunocompromised hosts infectious diseases. Additionally, I conduct research in India where I study factors influencing engagement in high-risk behaviors and health services utilization among young men who have sex with men and young injection drug users. I employ mixed-methods that include large cross-sectional database quantitative analyses as well as smaller qualitative studies. I have opportunities for students who may be interested in being involved with some of my smaller qualitative studies.

Mentoring
Available: 10/19/18, Expires: 10/31/20

Until September 2018, anal intercourse was a crime punishable by law in India. This law, along with cultural norms stipulating marriage to women has forced most men who have sex with men in India to remain hidden. Concealment of sexual identity has been shown to be associated with greater psychological stress as well as engagement in high-risk behaviors. Conversely, studies show that disclosure of sexual identity is associated with better health outcomes as well as access to health services. In September 2018, the Indian Supreme Court struck down S377A, the law criminalizing anal intercourse. In this qualitative study, we will explore the impact of decriminalization of anal intercourse on attitudes of young MSM towards sexual identity disclosure to family and health professionals. Students interested in this study will play key roles in literature review, design of qualitative survey, as well as data analysis. There may also be opportunities for travel to India.


Bibliographic
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  1. Ganapathi L, Caldas A, Miranda J, Köhler JR, Visner G, Sawicki G. Medical Deferred Action - Living on Borrowed Time. N Engl J Med. 2019 Oct 24; 381(17):1601-1603. PMID: 31577869.
    Citations:    
  2. Ganapathi L, Blumenthal J, Alawdah L, Lewis L, Gilarde J, Jones S, Milliren C, Kim HB, Sharma TS. Impact of standardized protocols for cytomegalovirus disease prevention in pediatric solid organ transplant recipients. Pediatr Transplant. 2019 11; 23(7):e13568. PMID: 31515909.
    Citations:    
  3. Ganapathi L, McFall AM, Srikrishnan AK, Kumar MS, Anand S, Lucas GM, Mehta SH, Harris SK, Solomon SS. Young people who inject drugs in India have high HIV incidence and behavioural risk: a cross-sectional study. J Int AIDS Soc. 2019 05; 22(5):e25287. PMID: 31116005.
    Citations:    
  4. Ganapathi L, Danziger-Isakov L, Kotton C, Kumar D, Huprikar S, Michaels MG, Englund JA. Trainee Needs in Pediatric Transplant Infectious Diseases Education. J Pediatric Infect Dis Soc. 2017 Sep 01; 6(3):301-304. PMID: 27760798.
    Citations:    Fields:    Translation:Humans
  5. Russ CM, Ganapathi L, Marangu D, Silverman M, Kija E, Bakeera-Kitaka S, Laving A. Perspectives of host faculty and trainees on international visiting faculty to paediatric academic departments in East Africa. BMJ Glob Health. 2016; 1(3):e000097. PMID: 28588960.
    Citations:    
  6. Ganapathi L, Arnold A, Jones S, Patterson A, Graham D, Harper M, Levy O. Use of cidofovir in pediatric patients with adenovirus infection. F1000Res. 2016; 5:758. PMID: 27239277.
    Citations: 2     
  7. van Haren SD, Ganapathi L, Bergelson I, Dowling DJ, Banks M, Samuels RC, Reed SG, Marshall JD, Levy O. In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. Cytokine. 2016 07; 83:99-109. PMID: 27081760.
    Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
  8. Ganapathi L, Somers M. IMAGES IN CLINICAL MEDICINE. A Child with Gross Hematuria. N Engl J Med. 2015 Aug 27; 373(9):e11. PMID: 26308700.
    Citations:    Fields:    Translation:HumansAnimals
  9. Ganapathi L, Van Haren S, Dowling DJ, Bergelson I, Shukla NM, Malladi SS, Balakrishna R, Tanji H, Ohto U, Shimizu T, David SA, Levy O. The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes. PLoS One. 2015; 10(8):e0134640. PMID: 26274907.
    Citations: 8     Fields:    Translation:HumansCells
  10. Ganapathi L, Martins Y, Schumann D, Russ C. Overcoming challenges to develop pediatric postgraduate training programs in low- and middle-income countries. Educ Health (Abingdon). 2014 Sep-Dec; 27(3):277-82. PMID: 25758392.
    Citations: 3     Fields:    Translation:Humans
  11. Ganapathi L, Pierre K, Hollowell M, Sandora TJ. An adolescent presenting with a pleural mass. Clin Pediatr (Phila). 2014 May; 53(5):504-6. PMID: 24634430.
    Citations:    Fields:    Translation:HumansCells
  12. Leung DT, Bogetz J, Itoh M, Ganapathi L, Pietroni MA, Ryan ET, Chisti MJ. Factors associated with encephalopathy in patients with Salmonella enterica serotype Typhi bacteremia presenting to a diarrheal hospital in Dhaka, Bangladesh. Am J Trop Med Hyg. 2012 Apr; 86(4):698-702. PMID: 22492156.
    Citations: 1     Fields:    Translation:HumansCells
  13. Rogers SM, Willis G, Al-Tayyib A, Villarroel MA, Turner CF, Ganapathi L, Zenilman J, Jadack R. Audio computer assisted interviewing to measure HIV risk behaviours in a clinic population. Sex Transm Infect. 2005 Dec; 81(6):501-7. PMID: 16326855.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.