Harvard Catalyst Profiles

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Christian Tientcha Happi, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U54HG007480 (HAPPI, CHRISTIAN T.) Sep 23, 2013 - Jun 30, 2022
    NIH/NHGRI
    Genomic Characterization and Surveillance of Microbial Threats in West Africa
    Role: Principal Investigator
  2. U01HG007480 (HAPPI, CHRISTIAN T.) Sep 23, 2013 - Jul 31, 2017
    NIH/NHGRI
    Host and Microbial Genetic Determinants of Febrile Illness in West Africa
    Role: Principal Investigator
  3. R03TW007757 (HAPPI, CHRISTIAN T) Dec 15, 2007 - Nov 30, 2010
    NIH/FIC
    Molecular determinants of P. falciparum resistance to ACTs in Nigeria.
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Blanton RE, Mock NB, Hiruy HN, Schieffelin JS, Doumbia S, Happi C, Samuels RJ, Oberhelman RA. African Resources and the Promise of Resilience against COVID-19. Am J Trop Med Hyg. 2020 Jun 03. PMID: 32500851.
    Citations:    
  2. Sakabe S, Hartnett JN, Ngo N, Goba A, Momoh M, Sandi JD, Kanneh L, Cubitt B, Garcia SD, Ware BC, Kotliar D, Robles-Sikisaka R, Gangavarapu K, Branco LM, Eromon P, Odia I, Ogbaini-Emovon E, Folarin O, Okogbenin S, Okokhere PO, Happi C, Sabeti PC, Andersen KG, Garry RF, de la Torre JC, Grant DS, Schieffelin JS, Oldstone MBA, Sullivan BM. Identification of Common CD8+ T Cell Epitopes from Lassa Fever Survivors in Nigeria and Sierra Leone. J Virol. 2020 Jun 01; 94(12). PMID: 32269122.
    Citations:    
  3. Boisen ML, Uyigue E, Aiyepada J, Siddle KJ, Oestereich L, Nelson DKS, Bush DJ, Rowland MM, Heinrich ML, Eromon P, Kayode AT, Odia I, Adomeh DI, Muoebonam EB, Akhilomen P, Okonofua G, Osiemi B, Omoregie O, Airende M, Agbukor J, Ehikhametalor S, Aire CO, Duraffour S, Pahlmann M, Böhm W, Barnes KG, Mehta S, Momoh M, Sandi JD, Goba A, Folarin OA, Ogbaini-Emovan E, Asogun DA, Tobin EA, Akpede GO, Okogbenin SA, Okokhere PO, Grant DS, Schieffelin JS, Sabeti PC, Günther S, Happi CT, Branco LM, Garry RF. Field evaluation of a Pan-Lassa rapid diagnostic test during the 2018 Nigerian Lassa fever outbreak. Sci Rep. 2020 May 26; 10(1):8724. PMID: 32457420.
    Citations:    
  4. Klitting R, Mehta SB, Oguzie JU, Oluniyi PE, Pauthner MG, Siddle KJ, Andersen KG, Happi CT, Sabeti PC. Lassa Virus Genetics. Curr Top Microbiol Immunol. 2020 May 17. PMID: 32418034.
    Citations:    
  5. Sullivan BM, Sakabe S, Hartnett JN, Ngo N, Goba A, Momoh M, Demby Sandi J, Kanneh L, Cubitt B, Garcia SD, Ware BC, Kotliar D, Robles-Sikisaka R, Gangavarapu K, Branco L, Eromon P, Odia I, Ogbaini-Emovon E, Folarin O, Okogbenin S, Okokhere PO, Happi C, de la Torre JC, Sabeti PC, Andersen KG, Garry RF, Grant DS, Schieffelin JS, Oldstone MBA. High crossreactivity of human T cell responses between Lassa virus lineages. PLoS Pathog. 2020 03; 16(3):e1008352. PMID: 32142546.
    Citations:    
  6. Ajogbasile FV, Oguzie JU, Oluniyi PE, Eromon PE, Uwanibe JN, Mehta SB, Siddle KJ, Odia I, Winnicki SM, Akpede N, Akpede G, Okogbenin S, Ogbaini-Emovon E, MacInnis BL, Folarin OA, Modjarrad K, Schaffner SF, Tomori O, Ihekweazu C, Sabeti PC, Happi CT. Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria. Sci Rep. 2020 02 21; 10(1):3180. PMID: 32081931.
    Citations:    
  7. Cross RW, Xu R, Matassov D, Hamm S, Latham TE, Gerardi CS, Nowak RM, Geisbert JB, Ota-Setlik A, Agans KN, Luckay A, Witko SE, Soukieh L, Deer DJ, Mire CE, Feldmann H, Happi C, Fenton KA, Eldridge JH, Geisbert TW. Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death. J Clin Invest. 2020 01 02; 130(1):539-551. PMID: 31820871.
    Citations:    
  8. Akpede GO, Asogun DA, Okogbenin SA, Dawodu SO, Momoh MO, Dongo AE, Ike C, Tobin E, Akpede N, Ogbaini-Emovon E, Adewale AE, Ochei O, Onyeke F, Okonofua MO, Atafo RO, Odia I, Adomeh DI, Odigie G, Ogbeifun C, Muoebonam E, Ihekweazu C, Ramharter M, Colubri A, Sabeti PC, Happi CT, Günther S, Agbonlahor DE. Corrigendum: Caseload and Case Fatality of Lassa Fever in Nigeria, 2001-2018: A Specialist Center's Experience and Its Implications. Front Public Health. 2019; 7:251. PMID: 31544101.
    Citations:    
  9. Akano K, Fatunmbi B, Ntadom G, Ayede AI, Aderoyeje T, Bakre A, Alebiosu OT, Akpoborie O, Okafor C, Gbotosho GO, Folarin OA, Ebenebe JC, Ambe J, Wammanda R, Jiya N, Finomo F, Emechebe G, Mokuolu O, Agomo C, Oguche S, Happi C, Sowunmi A. Clinical illness and outcomes in Nigerian children with persistent early-appearing anaemia following initiation of artemisinin-based combination treatments of uncomplicated falciparum malaria. Parasite. 2019; 26:56. PMID: 31516119.
    Citations:    
  10. Happi AN, Happi CT, Schoepp RJ. Lassa fever diagnostics: past, present, and future. Curr Opin Virol. 2019 08; 37:132-138. PMID: 31518896.
    Citations:    
  11. Sowunmi A, Ntadom G, Akano K, Ibironke FO, Ayede AI, Agomo C, Folarin OA, Gbotosho GO, Happi C, Oguche S, Okafor HU, Meremikwu M, Agomo P, Ogala W, Watila I, Mokuolu O, Finomo F, Ebenebe JC, Jiya N, Ambe J, Wammanda R, Emechebe G, Oyibo W, Useh F, Aderoyeje T, Dokunmu TM, Alebiosu OT, Amoo S, Basorun OK, Wewe OA, Okafor C, Akpoborie O, Fatunmbi B, Adewoye EO, Ezeigwe NM, Oduola A. Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line antimalarials in Nigeria. Infect Dis Poverty. 2019 Aug 06; 8(1):69. PMID: 31383040.
    Citations:    
  12. Okogbenin S, Okoeguale J, Akpede G, Colubri A, Barnes KG, Mehta S, Eifediyi R, Okogbo F, Eigbefoh J, Momoh M, Rafiu M, Adomeh D, Odia I, Aire C, Atafo R, Okonofua M, Pahlman M, Becker-Ziaja B, Asogun D, Okokhere P, Happi C, Günther S, Sabeti PC, Ogbaini-Emovon E. Retrospective Cohort Study of Lassa Fever in Pregnancy, Southern Nigeria. Emerg Infect Dis. 2019 08; 25(8). PMID: 31310586.
    Citations:    
  13. Akpede GO, Asogun DA, Okogbenin SA, Dawodu SO, Momoh MO, Dongo AE, Ike C, Tobin E, Akpede N, Ogbaini-Emovon E, Adewale AE, Ochei O, Onyeke F, Okonofua MO, Atafo RO, Odia I, Adomeh DI, Odigie G, Ogbeifun C, Muebonam E, Ihekweazu C, Ramharter M, Colubri A, Sarbeti PC, Happi CT, Günther S, Agbonlahor DE. Caseload and Case Fatality of Lassa Fever in Nigeria, 2001-2018: A Specialist Center's Experience and Its Implications. Front Public Health. 2019; 7:170. PMID: 31294014.
    Citations:    
  14. Ogunro BN, Olugasa BO, Kayode A, Ishola OO, Kolawole ON, Odigie EA, Happi C. Detection of Antibody and Antigen for Lassa Virus Nucleoprotein in Monkeys from Southern Nigeria. J Epidemiol Glob Health. 2019 06; 9(2):125-127. PMID: 31241870.
    Citations:    
  15. Happi AN, Ugwu CA, Happi CT. Preparing for the next Ebola outbreak: in-country genomic capacity in Africa. Lancet Infect Dis. 2019 06; 19(6):569-570. PMID: 31000467.
    Citations:    
  16. Metsky HC, Siddle KJ, Gladden-Young A, Qu J, Yang DK, Brehio P, Goldfarb A, Piantadosi A, Wohl S, Carter A, Lin AE, Barnes KG, Tully DC, Corleis B, Hennigan S, Barbosa-Lima G, Vieira YR, Paul LM, Tan AL, Garcia KF, Parham LA, Odia I, Eromon P, Folarin OA, Goba A, Simon-Lorière E, Hensley L, Balmaseda A, Harris E, Kwon DS, Allen TM, Runstadler JA, Smole S, Bozza FA, Souza TML, Isern S, Michael SF, Lorenzana I, Gehrke L, Bosch I, Ebel G, Grant DS, Happi CT, Park DJ, Gnirke A, Sabeti PC, Matranga CB. Capturing sequence diversity in metagenomes with comprehensive and scalable probe design. Nat Biotechnol. 2019 02; 37(2):160-168. PMID: 30718881.
    Citations:    
  17. Bankole BE, Kayode AT, Nosamiefan IO, Eromon P, Baniecki ML, Daniels RF, Hamilton EJ, Durfee K, MacInnis B, Okafor H, Sowunmi A, Volkman SK, Sabeti P, Wirth D, Happi CT, Folarin OA. Characterization of Plasmodium falciparum structure in Nigeria with malaria SNPs barcode. Malar J. 2018 Dec 17; 17(1):472. PMID: 30558627.
    Citations:    Fields:    Translation:AnimalsCells
  18. Akano K, Ntadom G, Agomo C, Happi CT, Folarin OA, Gbotosho GO, Mokuolu O, Finomo F, Ebenebe JC, Jiya N, Ambe J, Wammanda R, Emechebe G, Basorun OK, Wewe OA, Amoo S, Ezeigwe N, Oguche S, Fatunmbi B, Sowunmi A. Parasite reduction ratio one day after initiation of artemisinin-based combination therapies and its relationship with parasite clearance time in acutely malarious children. Infect Dis Poverty. 2018 Dec 07; 7(1):122. PMID: 30522524.
    Citations:    
  19. Siddle KJ, Eromon P, Barnes KG, Mehta S, Oguzie JU, Odia I, Schaffner SF, Winnicki SM, Shah RR, Qu J, Wohl S, Brehio P, Iruolagbe C, Aiyepada J, Uyigue E, Akhilomen P, Okonofua G, Ye S, Kayode T, Ajogbasile F, Uwanibe J, Gaye A, Momoh M, Chak B, Kotliar D, Carter A, Gladden-Young A, Freije CA, Omoregie O, Osiemi B, Muoebonam EB, Airende M, Enigbe R, Ebo B, Nosamiefan I, Oluniyi P, Nekoui M, Ogbaini-Emovon E, Garry RF, Andersen KG, Park DJ, Yozwiak NL, Akpede G, Ihekweazu C, Tomori O, Okogbenin S, Folarin OA, Okokhere PO, MacInnis BL, Sabeti PC, Happi CT. Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018. N Engl J Med. 2018 11 01; 379(18):1745-1753. PMID: 30332564.
    Citations:    Fields:    Translation:HumansAnimalsCells
  20. Okokhere PO, Erameh CO, Alikah F, Akhideno PE, Iruolagbe CO, Osazuwa OO, Bankole IA, Adomeh DI, Odia I, Aire CO, Oyakhilome J, Agbukor J, Atafo RO, Asogun DA, Happi CT, Sabeti PC, Günther S, Akpede GO. Acute Lassa Virus Encephalitis with Lassa Virus in the Cerebrospinal Fluid but Absent in the Blood: A Case Report with a Positive Outcome. Case Rep Neurol. 2018 May-Aug; 10(2):150-158. PMID: 30057542.
    Citations:    
  21. Ebenebe JC, Ntadom G, Ambe J, Wammanda R, Jiya N, Finomo F, Emechebe G, Mokuolu O, Akano K, Agomo C, Folarin OA, Oguche S, Useh F, Oyibo W, Aderoyeje T, Abdulkadir M, Ezeigwe NM, Happi C, Sowunmi A. Efficacy of Artemisinin-Based Combination Treatments of Uncomplicated Falciparum Malaria in Under-Five-Year-Old Nigerian Children Ten Years Following Adoption as First-Line Antimalarials. Am J Trop Med Hyg. 2018 09; 99(3):649-664. PMID: 29943725.
    Citations:    Fields:    
  22. Yinka-Ogunleye A, Aruna O, Ogoina D, Aworabhi N, Eteng W, Badaru S, Mohammed A, Agenyi J, Etebu EN, Numbere TW, Ndoreraho A, Nkunzimana E, Disu Y, Dalhat M, Nguku P, Mohammed A, Saleh M, McCollum A, Wilkins K, Faye O, Sall A, Happi C, Mba N, Ojo O, Ihekweazu C. Reemergence of Human Monkeypox in Nigeria, 2017. Emerg Infect Dis. 2018 06; 24(6):1149-1151. PMID: 29619921.
    Citations: 2     Fields:    
  23. Herrera BB, Hamel DJ, Oshun P, Akinsola R, Akanmu AS, Chang CA, Eromon P, Folarin O, Adeyemi KT, Happi CT, Lu Y, Ogunsola F, Kanki PJ. A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals. PLoS Negl Trop Dis. 2018 05; 12(5):e0006530. PMID: 29795572.
    Citations:    Fields:    Translation:HumansCells
  24. Boisen ML, Hartnett JN, Shaffer JG, Goba A, Momoh M, Sandi JD, Fullah M, Nelson DKS, Bush DJ, Rowland MM, Heinrich ML, Koval AP, Cross RW, Barnes KG, Lachenauer AE, Lin AE, Nekoui M, Kotliar D, Winnicki SM, Siddle KJ, Gbakie M, Fonnie M, Koroma VJ, Kanneh L, Kulakosky PC, Hastie KM, Wilson RB, Andersen KG, Folarin OO, Happi CT, Sabeti PC, Geisbert TW, Saphire EO, Khan SH, Grant DS, Schieffelin JS, Branco LM, Garry RF. Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever. Sci Rep. 2018 04 12; 8(1):5939. PMID: 29651117.
    Citations:    Fields:    
  25. Okokhere P, Colubri A, Azubike C, Iruolagbe C, Osazuwa O, Tabrizi S, Chin E, Asad S, Ediale E, Rafiu M, Adomeh D, Odia I, Atafo R, Aire C, Okogbenin S, Pahlman M, Becker-Ziaja B, Asogun D, Fradet T, Fry B, Schaffner SF, Happi C, Akpede G, Günther S, Sabeti PC. Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study. Lancet Infect Dis. 2018 06; 18(6):684-695. PMID: 29523497.
    Citations:    Fields:    
  26. Sowunmi A, Fatunmbi B, Akano K, Wewe OA, Agomo C, Finomo F, Ebenebe J, Jiya N, Ambe J, Wammanda R, Ntadom G, Mokuolu O, Emechebe G, Ezeigwe N, Ayede AI, Adewoye EO, Gbotosho GO, Folarin OA, Happi CT, Oguche S, Oyibo WA, Useh F. Factors contributing to anaemia after uncomplicated falciparum malaria in under five year-old Nigerian children ten years following adoption of artemisinin-based combination therapies as first-line antimalarials. BMC Infect Dis. 2017 12 19; 17(1):781. PMID: 29258448.
    Citations: 1     Fields:    Translation:Humans
  27. Akhuemokhan OC, Ewah-Odiase RO, Akpede N, Ehimuan J, Adomeh DI, Odia I, Olomu SC, Pahlmann M, Becker-Ziaja B, Happi CT, Asogun DA, Okogbenin SA, Okokhere PO, Dawodu OS, Omoike IU, Sabeti PC, Günther S, Akpede GO. Prevalence of Lassa Virus Disease (LVD) in Nigerian children with fever or fever and convulsions in an endemic area. PLoS Negl Trop Dis. 2017 Jul; 11(7):e0005711. PMID: 28671959.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  28. Sowunmi A, Akano K, Ntadom G, Ayede A, Oguche S, Agomo C, Okafor H, Watila I, Meremikwu M, Ogala W, Agomo P, Adowoye E, Fatunmbi B, Aderoyeje T, Happi C, Gbotosho G, Folarin O. Anaemia following Artemisinin-Based Combination Treatments of Uncomplicated Plasmodium falciparum Malaria in Children: Temporal Patterns of Haematocrit and the Use of Uncomplicated Hyperparasitaemia as a Model for Evaluating Late-Appearing Anaemia. Chemotherapy. 2017; 62(4):231-238. PMID: 28448988.
    Citations: 1     Fields:    Translation:Humans
  29. Dudas G, Carvalho LM, Bedford T, Tatem AJ, Baele G, Faria NR, Park DJ, Ladner JT, Arias A, Asogun D, Bielejec F, Caddy SL, Cotten M, D'Ambrozio J, Dellicour S, Di Caro A, Diclaro JW, Duraffour S, Elmore MJ, Fakoli LS, Faye O, Gilbert ML, Gevao SM, Gire S, Gladden-Young A, Gnirke A, Goba A, Grant DS, Haagmans BL, Hiscox JA, Jah U, Kugelman JR, Liu D, Lu J, Malboeuf CM, Mate S, Matthews DA, Matranga CB, Meredith LW, Qu J, Quick J, Pas SD, Phan MVT, Pollakis G, Reusken CB, Sanchez-Lockhart M, Schaffner SF, Schieffelin JS, Sealfon RS, Simon-Loriere E, Smits SL, Stoecker K, Thorne L, Tobin EA, Vandi MA, Watson SJ, West K, Whitmer S, Wiley MR, Winnicki SM, Wohl S, Wölfel R, Yozwiak NL, Andersen KG, Blyden SO, Bolay F, Carroll MW, Dahn B, Diallo B, Formenty P, Fraser C, Gao GF, Garry RF, Goodfellow I, Günther S, Happi CT, Holmes EC, Kargbo B, Keïta S, Kellam P, Koopmans MPG, Kuhn JH, Loman NJ, Magassouba N, Naidoo D, Nichol ST, Nyenswah T, Palacios G, Pybus OG, Sabeti PC, Sall A, Ströher U, Wurie I, Suchard MA, Lemey P, Rambaut A. Virus genomes reveal factors that spread and sustained the Ebola epidemic. Nature. 2017 04 20; 544(7650):309-315. PMID: 28405027.
    Citations: 25     Fields:    Translation:HumansCellsPHPublic Health
  30. Sowunmi A, Akano K, Ntadom G, Ayede AI, Ibironke FO, Aderoyeje T, Adewoye EO, Fatunmbi B, Oguche S, Okafor HU, Watila I, Meremikwu M, Agomo P, Ogala W, Agomo C, Folarin OA, Gbotosho GO, Happi CT. Therapeutic efficacy and effects of artemisinin-based combination treatments on uncomplicated Plasmodium falciparum malaria -associated anaemia in Nigerian children during seven years of adoption as first-line treatments. Infect Dis Poverty. 2017 Feb 07; 6(1):36. PMID: 28173853.
    Citations: 1     Fields:    Translation:Humans
  31. Sowunmi A, Akano K, Ayede AI, Adewoye EO, Ntadom G, Fatunmbi B, Gbotosho GO, Folarin OA, Happi CT. Early rising asexual parasitaemia in Nigerian children following a first dose of artemisinin-based combination treatments of falciparum malaria. BMC Infect Dis. 2017 01 31; 17(1):110. PMID: 28143417.
    Citations: 2     Fields:    Translation:Humans
  32. Salu OB, James AB, Oke BO, Orenolu MR, Anyanwu RA, Abdullah MA, Happi C, Idris J, Abdus-Salam IA, Nasidi AS, Ogunsola FT, Tomori O, Omilabu SA. Biosafety level-2 laboratory diagnosis of Zaire Ebola virus disease imported from Liberia to Nigeria. Afr J Lab Med. 2016; 5(1):468. PMID: 28879118.
    Citations:    
  33. Goba A, Khan SH, Fonnie M, Fullah M, Moigboi A, Kovoma A, Sinnah V, Yoko N, Rogers H, Safai S, Momoh M, Koroma V, Kamara FK, Konowu E, Yillah M, French I, Mustapha I, Kanneh F, Foday M, McCarthy H, Kallon T, Kallon M, Naiebu J, Sellu J, Jalloh AA, Gbakie M, Kanneh L, Massaly JL, Kargbo D, Kargbo B, Vandi M, Gbetuwa M, Gevao SM, Sandi JD, Jalloh SC, Grant DS, Blyden SO, Crozier I, Schieffelin JS, McLellan SL, Jacob ST, Boisen ML, Hartnett JN, Cross RW, Branco LM, Andersen KG, Yozwiak NL, Gire SK, Tariyal R, Park DJ, Haislip AM, Bishop CM, Melnik LI, Gallaher WR, Wimley WC, He J, Shaffer JG, Sullivan BM, Grillo S, Oman S, Garry CE, Edwards DR, McCormick SJ, Elliott DH, Rouelle JA, Kannadka CB, Reyna AA, Bradley BT, Yu H, Yenni RE, Hastie KM, Geisbert JB, Kulakosky PC, Wilson RB, Oldstone MB, Pitts KR, Henderson LA, Robinson JE, Geisbert TW, Saphire EO, Happi CT, Asogun DA, Sabeti PC, Garry RF. An Outbreak of Ebola Virus Disease in the Lassa Fever Zone. J Infect Dis. 2016 10 15; 214(suppl 3):S110-S121. PMID: 27402779.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  34. Folarin OA, Ehichioya D, Schaffner SF, Winnicki SM, Wohl S, Eromon P, West KL, Gladden-Young A, Oyejide NE, Matranga CB, Deme AB, James A, Tomkins-Tinch C, Onyewurunwa K, Ladner JT, Palacios G, Nosamiefan I, Andersen KG, Omilabu S, Park DJ, Yozwiak NL, Nasidi A, Garry RF, Tomori O, Sabeti PC, Happi CT. Ebola Virus Epidemiology and Evolution in Nigeria. J Infect Dis. 2016 10 15; 214(suppl 3):S102-S109. PMID: 27377746.
    Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
  35. Yozwiak NL, Happi CT, Grant DS, Schieffelin JS, Garry RF, Sabeti PC, Andersen KG. Roots, Not Parachutes: Research Collaborations Combat Outbreaks. Cell. 2016 Jun 30; 166(1):5-8. PMID: 27368093.
    Citations: 5     Fields:    Translation:PHPublic Health
  36. Robinson JE, Hastie KM, Cross RW, Yenni RE, Elliott DH, Rouelle JA, Kannadka CB, Smira AA, Garry CE, Bradley BT, Yu H, Shaffer JG, Boisen ML, Hartnett JN, Zandonatti MA, Rowland MM, Heinrich ML, Martínez-Sobrido L, Cheng B, de la Torre JC, Andersen KG, Goba A, Momoh M, Fullah M, Gbakie M, Kanneh L, Koroma VJ, Fonnie R, Jalloh SC, Kargbo B, Vandi MA, Gbetuwa M, Ikponmwosa O, Asogun DA, Okokhere PO, Follarin OA, Schieffelin JS, Pitts KR, Geisbert JB, Kulakoski PC, Wilson RB, Happi CT, Sabeti PC, Gevao SM, Khan SH, Grant DS, Geisbert TW, Saphire EO, Branco LM, Garry RF. Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits. Nat Commun. 2016 05 10; 7:11544. PMID: 27161536.
    Citations: 18     Fields:    Translation:HumansCells
  37. Andersen KG, Shapiro BJ, Matranga CB, Sealfon R, Lin AE, Moses LM, Folarin OA, Goba A, Odia I, Ehiane PE, Momoh M, England EM, Winnicki S, Branco LM, Gire SK, Phelan E, Tariyal R, Tewhey R, Omoniwa O, Fullah M, Fonnie R, Fonnie M, Kanneh L, Jalloh S, Gbakie M, Saffa S, Karbo K, Gladden AD, Qu J, Stremlau M, Nekoui M, Finucane HK, Tabrizi S, Vitti JJ, Birren B, Fitzgerald M, McCowan C, Ireland A, Berlin AM, Bochicchio J, Tazon-Vega B, Lennon NJ, Ryan EM, Bjornson Z, Milner DA, Lukens AK, Broodie N, Rowland M, Heinrich M, Akdag M, Schieffelin JS, Levy D, Akpan H, Bausch DG, Rubins K, McCormick JB, Lander ES, Günther S, Hensley L, Okogbenin S, Schaffner SF, Okokhere PO, Khan SH, Grant DS, Akpede GO, Asogun DA, Gnirke A, Levin JZ, Happi CT, Garry RF, Sabeti PC. Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus. Cell. 2015 Aug 13; 162(4):738-50. PMID: 26276630.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  38. Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF, Sabeti PC. Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone. Cell. 2015 Jun 18; 161(7):1516-26. PMID: 26091036.
    Citations: 64     Fields:    Translation:HumansCellsPHPublic Health
  39. Stremlau MH, Andersen KG, Folarin OA, Grove JN, Odia I, Ehiane PE, Omoniwa O, Omoregie O, Jiang PP, Yozwiak NL, Matranga CB, Yang X, Gire SK, Winnicki S, Tariyal R, Schaffner SF, Okokhere PO, Okogbenin S, Akpede GO, Asogun DA, Agbonlahor DE, Walker PJ, Tesh RB, Levin JZ, Garry RF, Sabeti PC, Happi CT. Discovery of novel rhabdoviruses in the blood of healthy individuals from West Africa. PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003631. PMID: 25781465.
    Citations: 8     Fields:    Translation:HumansCells
  40. Falajiki YF, Akinola O, Abiodun OO, Happi CT, Sowunmi A, Gbotosho GO. Amodiaquine-Ciprofloxacin: a potential combination therapy against drug resistant malaria. Parasitology. 2015 May; 142(6):849-54. PMID: 25736371.
    Citations: 1     Fields:    Translation:Animals
  41. Kuhn JH, Andersen KG, Baize S, Bào Y, Bavari S, Berthet N, Blinkova O, Brister JR, Clawson AN, Fair J, Gabriel M, Garry RF, Gire SK, Goba A, Gonzalez JP, Günther S, Happi CT, Jahrling PB, Kapetshi J, Kobinger G, Kugelman JR, Leroy EM, Maganga GD, Mbala PK, Moses LM, Muyembe-Tamfum JJ, N'Faly M, Nichol ST, Omilabu SA, Palacios G, Park DJ, Paweska JT, Radoshitzky SR, Rossi CA, Sabeti PC, Schieffelin JS, Schoepp RJ, Sealfon R, Swanepoel R, Towner JS, Wada J, Wauquier N, Yozwiak NL, Formenty P. Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014. Viruses. 2014 Nov 24; 6(11):4760-99. PMID: 25421896.
    Citations: 34     Fields:    Translation:HumansCellsPHPublic Health
  42. Folarin OA, Happi AN, Happi CT. Empowering African genomics for infectious disease control. Genome Biol. 2014 Nov 07; 15(11):515. PMID: 25417758.
    Citations: 7     Fields:    Translation:Humans
  43. Schieffelin JS, Shaffer JG, Goba A, Gbakie M, Gire SK, Colubri A, Sealfon RS, Kanneh L, Moigboi A, Momoh M, Fullah M, Moses LM, Brown BL, Andersen KG, Winnicki S, Schaffner SF, Park DJ, Yozwiak NL, Jiang PP, Kargbo D, Jalloh S, Fonnie M, Sinnah V, French I, Kovoma A, Kamara FK, Tucker V, Konuwa E, Sellu J, Mustapha I, Foday M, Yillah M, Kanneh F, Saffa S, Massally JL, Boisen ML, Branco LM, Vandi MA, Grant DS, Happi C, Gevao SM, Fletcher TE, Fowler RA, Bausch DG, Sabeti PC, Khan SH, Garry RF. Clinical illness and outcomes in patients with Ebola in Sierra Leone. N Engl J Med. 2014 Nov 27; 371(22):2092-100. PMID: 25353969.
    Citations: 133     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  44. Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Lackner DF, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses. 2014 Sep 26; 6(9):3663-82. PMID: 25256396.
    Citations: 22     Fields:    Translation:HumansCells
  45. Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, Winnicki S, Matranga CB, Malboeuf CM, Qu J, Gladden AD, Schaffner SF, Yang X, Jiang PP, Nekoui M, Colubri A, Coomber MR, Fonnie M, Moigboi A, Gbakie M, Kamara FK, Tucker V, Konuwa E, Saffa S, Sellu J, Jalloh AA, Kovoma A, Koninga J, Mustapha I, Kargbo K, Foday M, Yillah M, Kanneh F, Robert W, Massally JL, Chapman SB, Bochicchio J, Murphy C, Nusbaum C, Young S, Birren BW, Grant DS, Scheiffelin JS, Lander ES, Happi C, Gevao SM, Gnirke A, Rambaut A, Garry RF, Khan SH, Sabeti PC. Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science. 2014 Sep 12; 345(6202):1369-72. PMID: 25214632.
    Citations: 294     Fields:    Translation:HumansCellsPHPublic Health
  46. Badejo JA, Abiodun OO, Akinola O, Happi CT, Sowunmi A, Gbotosho GO. Interaction between rifampicin, amodiaquine and artemether in mice infected with chloroquine resistant Plasmodium berghei. Malar J. 2014 Aug 05; 13:299. PMID: 25091936.
    Citations:    Fields:    Translation:Animals
  47. Rotimi C, Abayomi A, Abimiku A, Adabayeri VM, Adebamowo C, Adebiyi E, Ademola AD, Adeyemo A, Adu D, Affolabi D, Agongo G, Ajayi S, Akarolo-Anthony S, Akinyemi R, Akpalu A, Alberts M, Alonso Betancourt O, Alzohairy AM, Ameni G, Amodu O, Anabwani G, Andersen K, Arogundade F, Arulogun O, Asogun D, Bakare R, Balde N, Baniecki ML, Beiswanger C, Benkahla A, Bethke L, Boehnke M, Boima V, Brandful J, Brooks AI, Brosius FC, Brown C, Bucheton B, Burke DT, Burnett BG, Carrington-Lawrence S, Carstens N, Chisi J, Christoffels A, Cooper R, Cordell H, Crowther N, Croxton T, de Vries J, Derr L, Donkor P, Doumbia S, Duncanson A, Ekem I, El Sayed A, Engel ME, Enyaru JC, Everett D, Fadlelmola FM, Fakunle E, Fischbeck KH, Fischer A, Folarin O, Gamieldien J, Garry RF, Gaseitsiwe S, Gbadegesin R, Ghansah A, Giovanni M, Goesbeck P, Gomez-Olive FX, Grant DS, Grewal R, Guyer M, Hanchard NA, Happi CT, Hazelhurst S, Hennig BJ, Hertz- C, Hide W, Hilderbrandt F, Hugo-Hamman C, Ibrahim ME, James R, Jaufeerally-Fakim Y, Jenkins C, Jentsch U, Jiang PP, Joloba M, Jongeneel V, Joubert F, Kader M, Kahn K, Kaleebu P, Kapiga SH, Kassim SK, Kasvosve I, Kayondo J, Keavney B, Kekitiinwa A, Khan SH, Kimmel P, King MC, Kleta R, Koffi M, Kopp J, Kretzler M, Kumuthini J, Kyobe S, Kyobutungi C, Lackland DT, Lacourciere KA, Landouré G, Lawlor R, Lehner T, Lesosky M, Levitt N, Littler K, Lombard Z, Loring JF, Lyantagaye S, Macleod A, Madden EB, Mahomva CR, Makani J, Mamven M, Marape M, Mardon G, Marshall P, Martin DP, Masiga D, Mason R, Mate-Kole M, Matovu E, Mayige M, Mayosi BM, Mbanya JC, McCurdy SA, McCarthy MI, McIlleron H, Mc'Ligeyo SO, Merle C, Mocumbi AO, Mondo C, Moran JV, Motala A, Moxey-Mims M, Mpoloka WS, Msefula CL, Mthiyane T, Mulder N, Mulugeta Gh, Mumba D, Musuku J, Nagdee M, Nash O, Ndiaye D, Nguyen AQ, Nicol M, Nkomazana O, Norris S, Nsangi B, Nyarko A, Nyirenda M, Obe E, Obiakor R, Oduro A, Ofori-Acquah SF, Ogah O, Ogendo S, Ohene-Frempong K, Ojo A, Olanrewaju T, Oli J, Osafo C, Ouwe Missi Oukem-Boyer O, Ovbiagele B, Owen A, Owolabi MO, Owolabi L, Owusu-Dabo E, Pare G, Parekh R, Patterton HG, Penno MB, Peterson J, Pieper R, Plange-Rhule J, Pollak M, Puzak J, Ramesar RS, Ramsay M, Rasooly R, Reddy S, Sabeti PC, Sagoe K, Salako T, Samassékou O, Sandhu MS, Sankoh O, Sarfo FS, Sarr M, Shaboodien G, Sidibe I, Simo G, Simuunza M, Smeeth L, Sobngwi E, Soodyall H, Sorgho H, Sow Bah O, Srinivasan S, Stein DJ, Susser ES, Swanepoel C, Tangwa G, Tareila A, Tastan Bishop O, Tayo B, Tiffin N, Tinto H, Tobin E, Tollman SM, Traoré M, Treadwell MJ, Troyer J, Tsimako-Johnstone M, Tukei V, Ulasi I, Ulenga N, van Rooyen B, Wachinou AP, Waddy SP, Wade A, Wayengera M, Whitworth J, Wideroff L, Winkler CA, Winnicki S, Wonkam A, Yewondwos M, sen T, Yozwiak N, Zar H. Research capacity. Enabling the genomic revolution in Africa. Science. 2014 Jun 20; 344(6190):1346-8. PMID: 24948725.
    Citations: 79     Fields:    Translation:Humans
  48. Gbotosho GO, Okuboyejo T, Happi CT, Sowunmi A. Fall in hematocrit per 1000 parasites cleared from peripheral blood: a simple method for estimating drug-related fall in hematocrit after treatment of malaria infections. Am J Ther. 2014 May-Jun; 21(3):193-7. PMID: 22020083.
    Citations: 5     Fields:    Translation:HumansAnimals
  49. Shaffer JG, Grant DS, Schieffelin JS, Boisen ML, Goba A, Hartnett JN, Levy DC, Yenni RE, Moses LM, Fullah M, Momoh M, Fonnie M, Fonnie R, Kanneh L, Koroma VJ, Kargbo K, Ottomassathien D, Muncy IJ, Jones AB, Illick MM, Kulakosky PC, Haislip AM, Bishop CM, Elliot DH, Brown BL, Zhu H, Hastie KM, Andersen KG, Gire SK, Tabrizi S, Tariyal R, Stremlau M, Matschiner A, Sampey DB, Spence JS, Cross RW, Geisbert JB, Folarin OA, Happi CT, Pitts KR, Geske FJ, Geisbert TW, Saphire EO, Robinson JE, Wilson RB, Sabeti PC, Henderson LA, Khan SH, Bausch DG, Branco LM, Garry RF. Lassa fever in post-conflict sierra leone. PLoS Negl Trop Dis. 2014 Mar; 8(3):e2748. PMID: 24651047.
    Citations: 37     Fields:    Translation:HumansCells
  50. Matranga CB, Andersen KG, Winnicki S, Busby M, Gladden AD, Tewhey R, Stremlau M, Berlin A, Gire SK, England E, Moses LM, Mikkelsen TS, Odia I, Ehiane PE, Folarin O, Goba A, Kahn SH, Grant DS, Honko A, Hensley L, Happi C, Garry RF, Malboeuf CM, Birren BW, Gnirke A, Levin JZ, Sabeti PC. Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples. Genome Biol. 2014; 15(11):519. PMID: 25403361.
    Citations: 22     Fields:    Translation:HumansCells
  51. Sowunmi A, Gbotosho GO, Happi CT, Okuboyejo TM, Sijuade AO, Michael OS, Adewoye EO, Folarin O. Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria. Am J Ther. 2013 Jan; 20(1):48-56. PMID: 21192244.
    Citations: 1     Fields:    Translation:Humans
  52. Gire SK, Stremlau M, Andersen KG, Schaffner SF, Bjornson Z, Rubins K, Hensley L, McCormick JB, Lander ES, Garry RF, Happi C, Sabeti PC. Epidemiology. Emerging disease or diagnosis? Science. 2012 Nov 09; 338(6108):750-2. PMID: 23139320.
    Citations: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  53. Asogun DA, Adomeh DI, Ehimuan J, Odia I, Hass M, Gabriel M, Olschläger S, Becker-Ziaja B, Folarin O, Phelan E, Ehiane PE, Ifeh VE, Uyigue EA, Oladapo YT, Muoebonam EB, Osunde O, Dongo A, Okokhere PO, Okogbenin SA, Momoh M, Alikah SO, Akhuemokhan OC, Imomeh P, Odike MA, Gire S, Andersen K, Sabeti PC, Happi CT, Akpede GO, Günther S. Molecular diagnostics for lassa fever at Irrua specialist teaching hospital, Nigeria: lessons learnt from two years of laboratory operation. PLoS Negl Trop Dis. 2012; 6(9):e1839. PMID: 23029594.
    Citations: 29     Fields:    Translation:HumansCells
  54. Gbotosho GO, Happi CT, Sijuade A, Sowunmi A, Oduola A. Pharmacokinetic disposition of sulfadoxine in children with acute uncomplicated falciparum malaria treated with sulfadoxine-pyrimethamine in South West Nigeria. Am J Ther. 2012 Sep; 19(5):338-45. PMID: 19918170.
    Citations: 1     Fields:    Translation:Humans
  55. Gbotosho GO, Sowunmi A, Okuboyejo TM, Happi CT, Folarin OO, Adewoye EO. A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated falciparum malaria in children: comparison of therapeutic efficacy with standard dose regimen of artesunate and amodiaquine and artemether-lumefantrine. Am J Ther. 2012 Jul; 19(4):e122-31. PMID: 21519221.
    Citations: 3     Fields:    Translation:Humans
  56. Bustamante C, Folarin OA, Gbotosho GO, Batista CN, Mesquita EA, Brindeiro RM, Tanuri A, Struchiner CJ, Sowunmi A, Oduola A, Wirth DF, Zalis MG, Happi CT. In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes. J Infect Dis. 2012 Aug 01; 206(3):324-32. PMID: 22615315.
    Citations: 9     Fields:    Translation:HumansAnimals
  57. Andersen KG, Shylakhter I, Tabrizi S, Grossman SR, Happi CT, Sabeti PC. Genome-wide scans provide evidence for positive selection of genes implicated in Lassa fever. Philos Trans R Soc Lond B Biol Sci. 2012 Mar 19; 367(1590):868-77. PMID: 22312054.
    Citations: 35     Fields:    Translation:HumansCells
  58. Gbotosho GO, Happi CT, Lawal O, Sijuade A, Sowunmi A, Oduola A. A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans. Malar J. 2012 Feb 27; 11:59. PMID: 22369125.
    Citations: 1     Fields:    Translation:Humans
  59. Gbotosho GO, Folarin OA, Bustamante C, da Silva LH, Mesquita E, Sowunmi A, Zalis MG, Oduola AM, Happi CT. Different patterns of pfcrt and pfmdr1 polymorphisms in P. falciparum isolates from Nigeria and Brazil: the potential role of antimalarial drug selection pressure. Am J Trop Med Hyg. 2012 Feb; 86(2):211-3. PMID: 22302850.
    Citations: 10     Fields:    Translation:HumansAnimals
  60. Sowunmi A, Okuboyejo TM, Gbotosho GO, Happi CT. Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children before and after artemisinin-based combination treatments. Chemotherapy. 2011; 57(6):497-504. PMID: 22261842.
    Citations: 2     Fields:    Translation:Humans
  61. Sowunmi A, Akinrinola IA, Gbotosho GO, Okuboyejo TM, Happi CT. A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation. J Trop Pediatr. 2012 Aug; 58(4):263-8. PMID: 22052702.
    Citations: 1     Fields:    Translation:HumansAnimals
  62. Sowunmi A, Okuboyejo TM, Gbotosho GO, Happi CT. Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children. BMC Infect Dis. 2011 Oct 09; 11:268. PMID: 21982211.
    Citations: 2     Fields:    Translation:HumansAnimals
  63. Folarin OA, Bustamante C, Gbotosho GO, Sowunmi A, Zalis MG, Oduola AM, Happi CT. In vitro amodiaquine resistance and its association with mutations in pfcrt and pfmdr1 genes of Plasmodium falciparum isolates from Nigeria. Acta Trop. 2011 Dec; 120(3):224-30. PMID: 21920347.
    Citations: 11     Fields:    Translation:HumansAnimals
  64. Gbotosho GO, Sowunmi A, Happi CT, Okuboyejo TM. Plasmodium falciparum gametocyte carriage, sex ratios and asexual parasite rates in Nigerian children before and after a treatment protocol policy change instituting the use of artemisinin-based combination therapies. Mem Inst Oswaldo Cruz. 2011 Sep; 106(6):685-90. PMID: 22012222.
    Citations: 8     Fields:    Translation:HumansAnimals
  65. Gbotosho GO, Happi CT, Woranola O, Abiodun OO, Sowunmi A, Oduola AM. Interaction between ciprofloxacin and chloroquine in mice infected with chloroquine resistant Plasmodium berghei: interaction between ciprofloxacin and chloroqune. Parasitol Res. 2012 Feb; 110(2):895-9. PMID: 21826489.
    Citations: 2     Fields:    Translation:Animals
  66. Gbotosho GO, Sowunmi A, Okuboyejo TM, Happi CT, Michael OS, Folarin OA, Adewoye EO. Plasmodium falciparum gametocyte carriage, emergence, clearance and population sex ratios in anaemic and non-anaemic malarious children. Mem Inst Oswaldo Cruz. 2011 Aug; 106(5):562-9. PMID: 21894377.
    Citations: 3     Fields:    Translation:HumansAnimals
  67. Gbotosho GO, Sowunmi A, Happi CT, Okuboyejo TM. Therapeutic efficacies of artemisinin-based combination therapies in Nigerian children with uncomplicated falciparum malaria during five years of adoption as first-line treatments. Am J Trop Med Hyg. 2011 Jun; 84(6):936-43. PMID: 21633031.
    Citations: 10     Fields:    Translation:HumansAnimals
  68. Gbotosho GO, Sowunmi A, Okuboyejo TM, Happi CT. Oral artesunate-amodiaquine and artemether-lumefantrine in the treatment of uncomplicated hyperparasitaemic Plasmodium falciparum malaria in children. J Trop Pediatr. 2012 Apr; 58(2):151-3. PMID: 21622538.
    Citations: 2     Fields:    Translation:HumansAnimals
  69. Sowunmi A, Gbotosho GO, Happi CT, Folarin O, Okuboyejo T, Michael O, Fatunmbi B. Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment. Am J Ther. 2011 May; 18(3):190-7. PMID: 20683244.
    Citations: 5     Fields:    Translation:HumansAnimals
  70. Gbotosho GO, Sowunmi A, Okuboyejo TM, Happi CT, Folarin OA, Michael OS, Adewoye EO. Therapeutic efficacy and effects of artemether-lumefantrine and artesunate-amodiaquine coformulated or copackaged on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in Southwest Nigeria. Am J Trop Med Hyg. 2011 May; 84(5):813-9. PMID: 21540395.
    Citations: 11     Fields:    Translation:Humans
  71. Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet. 2011 Apr; 7(4):e1001383. PMID: 21533027.
    Citations: 39     Fields:    Translation:Animals
  72. Michael OS, Gbotosho GO, Folarin OA, Okuboyejo T, Sowunmi A, Oduola AM, Happi CT. Early variations in plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance. Malar J. 2010 Nov 22; 9:335. PMID: 21092220.
    Citations: 15     Fields:    Translation:HumansAnimals
  73. Gbotosho GO, Happi CT, Folarin O, Keyamo O, Sowunmi A, Oduola AM. Rapid detection of lactate dehydrogenase and genotyping of Plasmodium falciparum in saliva of children with acute uncomplicated malaria. Am J Trop Med Hyg. 2010 Sep; 83(3):496-501. PMID: 20810809.
    Citations: 6     Fields:    Translation:HumansAnimals
  74. Abiodun OO, Gbotosho GO, Ajaiyeoba EO, Happi CT, Hofer S, Wittlin S, Sowunmi A, Brun R, Oduola AM. Comparison of SYBR Green I-, PicoGreen-, and [3H]-hypoxanthine-based assays for in vitro antimalarial screening of plants from Nigerian ethnomedicine. Parasitol Res. 2010 Mar; 106(4):933-9. PMID: 20165881.
    Citations: 8     Fields:    Translation:HumansAnimals
  75. Sowunmi A, Adewoye EO, Gbotsho GO, Happi CT, Sijuade A, Folarin OA, Okuboyejo TM, Michael OS. Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children. Malar J. 2010 Feb 15; 9:53. PMID: 20156350.
    Citations: 12     Fields:    Translation:HumansAnimals
  76. Gbotosho GO, Happi CT, Ganiyu A, Ogundahunsi OA, Sowunmi A, Oduola AM. Potential contribution of prescription practices to the emergence and spread of chloroquine resistance in south-west Nigeria: caution in the use of artemisinin combination therapy. Malar J. 2009 Dec 30; 8:313. PMID: 20042098.
    Citations: 13     Fields:    Translation:HumansAnimals
  77. Sowunmi A, Nkogho OO, Okuboyejo TM, Gbotosho GO, Happi CT, Adewoye EO. Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children. Malar J. 2009 Dec 16; 8:297. PMID: 20015395.
    Citations: 6     Fields:    Translation:HumansAnimals
  78. Sowunmi A, Gbotosho GO, Happi C, Okuboyejo T, Folarin O, Balogun S, Michael O. Therapeutic efficacy and effects of artesunate-mefloquine and mefloquine alone on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in southwest Nigeria. Am J Trop Med Hyg. 2009 Dec; 81(6):979-86. PMID: 19996425.
    Citations: 10     Fields:    Translation:HumansAnimals
  79. Sowunmi A, Gbotosho GO, Happi CT, Fateye BA. Factors contributing to anaemia after uncomplicated Plasmodiumfalciparum malaria in children. Acta Trop. 2010 Feb; 113(2):155-61. PMID: 19874795.
    Citations: 10     Fields:    Translation:HumansAnimals
  80. Gbotosho GO, Happi CT, Sijuade AO, Sowunmi A, Oduola AM. A simple cost-effective high performance liquid chromatographic assay of sulphadoxine in whole blood spotted on filter paper for field studies. Malar J. 2009 Oct 24; 8:238. PMID: 19852850.
    Citations: 1     Fields:    Translation:HumansCells
  81. Sowunmi A, Gbotosho GO, Happi CT, Folarin OA, Balogun ST. Population structure of Plasmodium falciparum gametocyte sex ratios in malarious children in an endemic area. Parasitol Int. 2009 Dec; 58(4):438-43. PMID: 19723589.
    Citations: 6     Fields:    Translation:HumansAnimalsPHPublic Health
  82. Happi CT, Gbotosho GO, Folarin OA, Sowunmi A, Hudson T, O'Neil M, Milhous W, Wirth DF, Oduola AM. Selection of Plasmodium falciparum multidrug resistance gene 1 alleles in asexual stages and gametocytes by artemether-lumefantrine in Nigerian children with uncomplicated falciparum malaria. Antimicrob Agents Chemother. 2009 Mar; 53(3):888-95. PMID: 19075074.
    Citations: 45     Fields:    Translation:HumansAnimals
  83. Sowunmi A, Balogun ST, Gbotosho GO, Happi CT. Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children. Mem Inst Oswaldo Cruz. 2008 Dec; 103(8):754-9. PMID: 19148412.
    Citations: 2     Fields:    Translation:HumansAnimals
  84. Sowunmi A, Balogun ST, Gbotosho GO, Happi CT. Plasmodium falciparum gametocyte sex ratios in symptomatic children treated with antimalarial drugs. Acta Trop. 2009 Feb; 109(2):108-17. PMID: 19027703.
    Citations: 9     Fields:    Translation:HumansAnimals
  85. Sowunmi A, Balogun ST, Gbotosho GO, Happi CT. Effects of amodiaquine, artesunate, and artesunate-amodiaquine on Plasmodium falciparum malaria-associated anaemia in children. Acta Trop. 2009 Jan; 109(1):55-60. PMID: 18992209.
    Citations: 13     Fields:    Translation:HumansAnimals
  86. Ajayi IO, Browne EN, Bateganya F, Yar D, Happi C, Falade CO, Gbotosho GO, Yusuf B, Boateng S, Mugittu K, Cousens S, Nanyunja M, Pagnoni F. Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: a report from three study sites in sub-Saharan Africa. Malar J. 2008 Sep 27; 7:190. PMID: 18822170.
    Citations: 33     Fields:    Translation:Humans
  87. Sowunmi A, Balogun ST, Gbotosho GO, Happi CT. Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine. Malar J. 2008 Sep 02; 7:169. PMID: 18761752.
    Citations: 9     Fields:    Translation:HumansAnimals
  88. Fehintola FA, Adedeji AA, Gbotosho GO, Happi CT, Balogun ST, Folarin OA, Sijuade AO, Sowunmi A. Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of Plasmodium falciparum malaria in Nigerian children. J Infect Chemother. 2008 Jun; 14(3):188-94. PMID: 18574653.
    Citations: 2     Fields:    Translation:HumansAnimals
  89. Sowunmi A, Balogun T, Gbotosho GO, Happi CT, Adedeji AA, Bolaji OM, Fehintola FA, Folarin OA. Activities of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine against sexual-stage parasites in falciparum malaria in children. Chemotherapy. 2008; 54(3):201-8. PMID: 18560227.
    Citations: 7     Fields:    Translation:HumansAnimals
  90. Ajayi IO, Falade CO, Olley BO, Yusuf B, Gbotosho S, Iyiola T, Olaniyan O, Happi C, Munguti K, Pagnoni F. A qualitative study of the feasibility and community perception on the effectiveness of artemether-lumefantrine use in the context of home management of malaria in south-west Nigeria. BMC Health Serv Res. 2008 Jun 01; 8:119. PMID: 18513447.
    Citations: 18     Fields:    Translation:Humans
  91. Sowunmi A, Gbotosho GO, Adedeji AA, Tambo E, Bolaji OM, Happi CT, Fateye BA. Herpes simplex labialis in children with acute falciparum malaria. Acta Trop. 2008 Apr; 106(1):68-71. PMID: 18313630.
    Citations: 2     Fields:    Translation:HumansCells
  92. Gbotosho GO, Happi CT, Sijuade A, Ogundahunsi OA, Sowunmi A, Oduola AM. Comparative study of interactions between chloroquine and chlorpheniramine or promethazine in healthy volunteers: a potential combination-therapy phenomenon for resuscitating chloroquine for malaria treatment in Africa. Ann Trop Med Parasitol. 2008 Jan; 102(1):3-9. PMID: 18186973.
    Citations: 3     Fields:    Translation:HumansAnimals
  93. Plowe CV, Roper C, Barnwell JW, Happi CT, Joshi HH, Mbacham W, Meshnick SR, Mugittu K, Naidoo I, Price RN, Shafer RW, Sibley CH, Sutherland CJ, Zimmerman PA, Rosenthal PJ. World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. Malar J. 2007 Sep 06; 6:121. PMID: 17822535.
    Citations: 52     Fields:    Translation:HumansPHPublic Health
  94. Sowunmi A, Gbotosho GO, Happi CT, Adedeji AA, Fehintola FA, Folarin OA, Tambo E, Fateye BA. Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria. Am J Trop Med Hyg. 2007 Aug; 77(2):235-41. PMID: 17690392.
    Citations: 24     Fields:    Translation:HumansAnimals
  95. Sowunmi A, Gbotosho GO, Happi CT, Adedeji AA, Bolaji OM, Fehintola FA, Fateye BA, Oduola AM. Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo. Mem Inst Oswaldo Cruz. 2007 Jun; 102(3):417-9. PMID: 17568949.
    Citations: 3     Fields:    Translation:HumansAnimals
  96. Sowunmi A, Balogun T, Gbotosho GO, Happi CT, Adedeji AA, Fehintola FA. Activities of amodiaquine, artesunate, and artesunate-amodiaquine against asexual- and sexual-stage parasites in falciparum malaria in children. Antimicrob Agents Chemother. 2007 May; 51(5):1694-9. PMID: 17325222.
    Citations: 19     Fields:    Translation:HumansAnimals
  97. Sowunmi A, Gbotosho GO, Adedeji AA, Fateye BA, Sabitu MF, Happi CT, Fehintola FA. Effects of acute Plasmodium falciparum malaria on body weight in children in an endemic area. Parasitol Res. 2007 Jul; 101(2):343-9. PMID: 17323138.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  98. Falade CO, Fadero FF, Happi CT, Dada-Adegbola HO, Gbotosho GO, Ayede I, Falade AG, Oduola AM, Salako LA. Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine-pyrimethamine in the management of moderately severe malaria in Nigerian children. Am J Trop Med Hyg. 2007 Jan; 76(1):1-6. PMID: 17255220.
    Citations: 1     Fields:    Translation:Humans
  99. Happi CT, Gbotosho GO, Folarin OA, Milner D, Sarr O, Sowunmi A, Kyle DE, Milhous WK, Wirth DF, Oduola AM. Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa. Malar J. 2006 Oct 04; 5:82. PMID: 17020611.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  100. Gbotosho GO, Ogundahunsi OA, Happi CT, Kyle DE, Gerena L, Milhous WK, Sowunmi A, Oduola AM, Salako LA. The effects of alpha1-acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum. Ann Trop Med Parasitol. 2006 Oct; 100(7):571-8. PMID: 16989682.
    Citations: 2     Fields:    Translation:Animals
  101. Sowunmi A, Gbotosho GO, Adedeji AA, Tambo E, Fateye BA, Happi CT, Amoo AO. The effects of artemether-lumefantrine vs amodiaquine-sulfalene-pyrimethamine on the hepatomegaly associated with Plasmodium falciparum malaria in children. Parasitol Res. 2007 Feb; 100(3):511-7. PMID: 17013650.
    Citations: 1     Fields:    Translation:HumansAnimals
  102. Happi CT, Gbotosho GO, Folarin OA, Sowunmi A, Bolaji OM, Fateye BA, Kyle DE, Milhous W, Wirth DF, Oduola AM. Linkage disequilibrium between two distinct loci in chromosomes 5 and 7 of Plasmodium falciparum and in vivo chloroquine resistance in Southwest Nigeria. Parasitol Res. 2006 Dec; 100(1):141-8. PMID: 16874478.
    Citations: 9     Fields:    Translation:HumansAnimals
  103. Happi CT, Gbotosho GO, Folarin OA, Bolaji OM, Sowunmi A, Kyle DE, Milhous W, Wirth DF, Oduola AM. Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria. Am J Trop Med Hyg. 2006 Jul; 75(1):155-61. PMID: 16837724.
    Citations: 44     Fields:    Translation:HumansAnimals
  104. Ajaiyeoba EO, Abiodun OO, Falade MO, Ogbole NO, Ashidi JS, Happi CT, Akinboye DO. In vitro cytotoxicity studies of 20 plants used in Nigerian antimalarial ethnomedicine. Phytomedicine. 2006 Mar; 13(4):295-8. PMID: 16492535.
    Citations: 9     Fields:    Translation:Animals
  105. Happi CT, Gbotosho GO, Folarin OA, Akinboye DO, Yusuf BO, Ebong OO, Sowunmi A, Kyle DE, Milhous W, Wirth DF, Oduola AM. Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine-pyrimethamine resistance in malaria-infected patients from Nigeria. Acta Trop. 2005 Sep; 95(3):183-93. PMID: 16023986.
    Citations: 34     Fields:    Translation:HumansAnimals
  106. Happi CT, Gbotosho GO, Sowunmi A, Falade CO, Akinboye DO, Oladepo O, Oduola AM. Malaria diagnosis: false negative parasight-F tests in falciparum malaria patients in Nigeria. Afr J Med Med Sci. 2004 Mar; 33(1):15-8. PMID: 15490787.
    Citations: 4     Fields:    Translation:HumansAnimals
  107. Happi CT, Gbotosho GO, Sowunmi A, Falade CO, Akinboye DO, Gerena L, Kyle DE, Milhous W, Wirth DF, Oduola AM. Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria. Am J Trop Med Hyg. 2004 Jan; 70(1):20-6. PMID: 14971693.
    Citations: 29     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.