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Jonathan Michael Winograd, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nam AS, Easow JM, Chico-Calero I, Villiger M, Welt J, Borschel GH, Winograd JM, Randolph MA, Redmond RW, Vakoc BJ. Wide-Field Functional Microscopy of Peripheral Nerve Injury and Regeneration. Sci Rep. 2018 Sep 18; 8(1):14004. PMID: 30228335.
    Citations:    Fields:    
  2. Ruscic KJ, Zamora-Berridi GJ, McGovern FJ, Cetrulo C, Winograd JM, Eberlin KR, Bojovic B, Ko DS, Anderson TA. Epidural Anesthesia to Facilitate Organ Blood Flow During the First Penile Transplantation in the United States: A Case Report. A A Pract. 2018 May 01; 10(9):232-234. PMID: 29708917.
    Citations:    
  3. Cetrulo CL, Li K, Salinas HM, Treiser MD, Schol I, Barrisford GW, McGovern FJ, Feldman AS, Grant MT, Tanrikut C, Lee JH, Ehrlichman RJ, Holzer PW, Choy GM, Liu RW, Ng ZY, Lellouch AG, Kurtz JM, Austen WG, Winograd JM, Bojovic B, Eberlin KR, Rosales IA, Colvin RB, Ko DSC. Penis Transplantation: First US Experience. Ann Surg. 2018 May; 267(5):983-988. PMID: 28509699.
    Citations: 5     Fields:    
  4. Sobti N, Ji E, Brown RL, Cetrulo CL, Colwell AS, Winograd JM, Austen WG, Liao EC. Evaluation of Acellular Dermal Matrix Efficacy in Prosthesis-Based Breast Reconstruction. Plast Reconstr Surg. 2018 03; 141(3):541-549. PMID: 29481386.
    Citations:    Fields:    Translation:Humans
  5. Ruscic KJ, Zamora-Berridi GJ, McGovern FJ, Cetrulo C, Winograd JM, Eberlin KR, Bojovic B, Ko DS, Anderson TA. Epidural Anesthesia to Facilitate Organ Blood Flow During the First Penile Transplantation in the United States: A Case Report. A A Case Rep. 2017 Nov 16. PMID: 29189286.
    Citations:    
  6. Senthil-Kumar P, Ng-Glazier JH, Randolph MA, Bodugoz-Senturk H, Muratoglu OK, Kochevar IE, Winograd JM, Redmond RW. An intraluminal stent facilitates light-activated vascular anastomosis. J Trauma Acute Care Surg. 2017 07; 83(1 Suppl 1):S43-S49. PMID: 28383474.
    Citations:    Fields:    Translation:Animals
  7. Cetrulo CL, Ng ZY, Winograd JM, Eberlin KR. The Advent of Vascularized Composite Allotransplantation. Clin Plast Surg. 2017 Apr; 44(2):425-429. PMID: 28340673.
    Citations:    Fields:    Translation:Humans
  8. Faulkner HR, Colwell AS, Liao EC, Winograd JM, Austen WG. Thermal Injury to Reconstructed Breasts from Commonly Used Warming Devices: A Risk for Reconstructive Failure. Plast Reconstr Surg Glob Open. 2016 Oct; 4(10):e1033. PMID: 27826463.
    Citations: 2     
  9. Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Valerio IL, Fleming ME, Kochevar IE, Winograd JM, Redmond RW. Erratum: Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury. J Reconstr Microsurg. 2016 11; 32(9):e1. PMID: 27341523.
    Citations:    Fields:    
  10. Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Winograd JM, Redmond RW. Improving Outcomes in Immediate and Delayed Nerve Grafting of Peripheral Nerve Gaps Using Light-Activated Sealing of Neurorrhaphy Sites with Human Amnion Wraps. Plast Reconstr Surg. 2016 Mar; 137(3):887-95. PMID: 26910669.
    Citations: 2     Fields:    Translation:HumansAnimals
  11. Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Valerio IL, Fleming ME, Kochevar IE, Winograd JM, Redmond RW. Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury. J Reconstr Microsurg. 2016 Jul; 32(6):421-30. PMID: 26878685.
    Citations:    Fields:    Translation:AnimalsCells
  12. Mattos D, Gfrerer L, Reish RG, Hughes KS, Cetrulo C, Colwell AS, Winograd JM, Yaremchuk MJ, Austen WG, Liao EC. Lifetime Costs of Prophylactic Mastectomies and Reconstruction versus Surveillance. Plast Reconstr Surg. 2015 Dec; 136(6):730e-40e. PMID: 26595028.
    Citations: 2     Fields:    Translation:Humans
  13. Mattos D, Gfrerer L, Ling IT, Reish RG, Hughes KS, Halpern EF, Cetrulo C, Colwell AS, Winograd JM, Yaremchuk MJ, Austen WG, Liao EC. Occult Histopathology and Its Predictors in Contralateral and Bilateral Prophylactic Mastectomies. Ann Surg Oncol. 2016 Mar; 23(3):767-75. PMID: 26577123.
    Citations:    Fields:    Translation:Humans
  14. Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Valerio IL, Fleming ME, Winograd JM, Redmond RW. Light-Activated Sealing of Nerve Graft Coaptation Sites Improves Outcome following Large Gap Peripheral Nerve Injury. Plast Reconstr Surg. 2015 Oct; 136(4):739-50. PMID: 26397251.
    Citations: 2     Fields:    Translation:HumansAnimals
  15. Kobraei EM, Eberlin KR, Ricci JA, Reish RG, Winograd JM, Cetrulo CL. GHOST Protocol: Greatest Healing Opportunity for Soft Tissue, a Treatment Paradigm for Complex Sarcoma Reconstruction. Am Surg. 2015 Jun; 81(6):557-63. PMID: 26031266.
    Citations: 1     Fields:    Translation:Humans
  16. Henry FP, Wang Y, Rodriguez CL, Randolph MA, Rust EA, Winograd JM, de Boer JF, Park BH. In vivo optical microscopy of peripheral nerve myelination with polarization sensitive-optical coherence tomography. J Biomed Opt. 2015 Apr; 20(4):046002. PMID: 25858593.
    Citations: 6     Fields:    Translation:AnimalsCells
  17. Reish RG, Lin A, Phillips NA, Winograd J, Liao EC, Cetrulo CL, Smith BL, Austen WG, Colwell AS. Breast reconstruction outcomes after nipple-sparing mastectomy and radiation therapy. Plast Reconstr Surg. 2015 Apr; 135(4):959-66. PMID: 25811561.
    Citations: 9     Fields:    Translation:Humans
  18. Fairbairn NG, Meppelink AM, Ng-Glazier J, Randolph MA, Winograd JM. Augmenting peripheral nerve regeneration using stem cells: A review of current opinion. World J Stem Cells. 2015 Jan 26; 7(1):11-26. PMID: 25621102.
    Citations: 11     
  19. Eberlin KR, Leonard DA, Austen WG, Yaremchuk MJ, Mudgal CS, Winograd JM, Cetrulo CL. The volar forearm fasciocutaneous extension: a strategy to maximize vascular outflow in post-burn injury hand transplantation. Plast Reconstr Surg. 2014 Oct; 134(4):731-5. PMID: 25357032.
    Citations: 1     Fields:    Translation:Humans
  20. Fitzpatrick AM, Gao LL, Smith BL, Cetrulo CL, Colwell AS, Winograd JM, Yaremchuk MJ, Austen WG, Liao EC. Cost and outcome analysis of breast reconstruction paradigm shift. Ann Plast Surg. 2014 Aug; 73(2):141-9. PMID: 23407253.
    Citations: 6     Fields:    Translation:Humans
  21. Jung Y, Ng JH, Keating CP, Senthil-Kumar P, Zhao J, Randolph MA, Winograd JM, Evans CL. Comprehensive evaluation of peripheral nerve regeneration in the acute healing phase using tissue clearing and optical microscopy in a rodent model. PLoS One. 2014; 9(4):e94054. PMID: 24714405.
    Citations: 12     Fields:    Translation:Animals
  22. Reish RG, Lin AM, Austen WG, Winograd J, Liao EC, Cetrulo CL, Smith BL, Colwell AS. Abstract 25: breast reconstruction outcomes after nipple-sparing mastectomy and radiation therapy. Plast Reconstr Surg. 2014 Apr; 133(4 Suppl):991. PMID: 24675318.
    Citations:    
  23. Tessler O, Mattos D, Vorstenbosch J, Jones D, Winograd JM, Liao EC, Austen WG. A methodological analysis of the plastic surgery cost-utility literature using established guidelines. Plast Reconstr Surg. 2014 Apr; 133(4):584e-92e. PMID: 24675210.
    Citations: 1     Fields:    Translation:Humans
  24. Kuo P, Hartzell TL, Eberlin KR, Miao D, Zurakowski D, Winograd JM, Day CS. The characteristics of referring facilities and transferred hand surgery patients: factors associated with emergency patient transfers. J Bone Joint Surg Am. 2014 Mar 19; 96(6):e48. PMID: 24647515.
    Citations:    Fields:    Translation:Humans
  25. Colwell AS, Tessler O, Lin AM, Liao E, Winograd J, Cetrulo CL, Tang R, Smith BL, Austen WG. Breast reconstruction following nipple-sparing mastectomy: predictors of complications, reconstruction outcomes, and 5-year trends. Plast Reconstr Surg. 2014 Mar; 133(3):496-506. PMID: 24572843.
    Citations: 42     Fields:    Translation:Humans
  26. Mattos D, Reish RG, Cetrulo C, Colwell AS, Winograd JM, Yaremchuk MJ, Austen WG, Liao EC. Abstract 43: Prophylactic Mastectomies: Implications of Occult Histology and Lifetime Cost of Surveillance vs. Surgery. Plast Reconstr Surg. 2014 Mar; 133(3 Suppl):53-4. PMID: 25942154.
    Citations:    Fields:    
  27. Lin A, Liao E, Winograd J, Cetrulo C, Tang R, Smith BL, Austen WG, Colwell AS. Abstract 98: nipple-sparing mastectomy in patients with previous breast surgery: comparative analysis of 123 immediate reconstructions. Plast Reconstr Surg. 2014 Mar; 133(3 Suppl):112. PMID: 25942209.
    Citations: 1     Fields:    
  28. Nyame TT, Holzer PW, Helm DL, Maman DY, Winograd JM, Cetrulo CL. SPLIT rectus abdominis myocutaneous double free flap for extremity reconstruction. Microsurgery. 2014 Jan; 34(1):54-7. PMID: 24123062.
    Citations: 2     Fields:    Translation:Humans
  29. Susarla S, Gordon PE, Attarpour AR, Winograd JM, Peacock ZS. Use of a mandibular plate to maintain intergonial width in a partially edentulous patient undergoing mandibular symphysis reconstruction. Craniomaxillofac Trauma Reconstr. 2013 Dec; 6(4):281-4. PMID: 24436775.
    Citations:    
  30. Reish RG, Damjanovic B, Austen WG, Winograd J, Liao EC, Cetrulo CL, Balkin DM, Colwell AS. Infection following implant-based reconstruction in 1952 consecutive breast reconstructions: salvage rates and predictors of success. Plast Reconstr Surg. 2013 Jun; 131(6):1223-30. PMID: 23714788.
    Citations: 18     Fields:    Translation:HumansCells
  31. Morrow M, Winograd JM, Freer PE, Eichhorn JH. Case records of the Massachusetts General Hospital. Case 8-2013. A 48-year-old woman with carcinoma in situ of the breast. N Engl J Med. 2013 Mar 14; 368(11):1046-53. PMID: 23484832.
    Citations: 1     Fields:    Translation:Humans
  32. Eberlin KR, Hartzell TL, Kuo P, Winograd J, Day C. Patients transferred for emergency upper extremity evaluation: does insurance status matter? Plast Reconstr Surg. 2013 Mar; 131(3):593-600. PMID: 23446571.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  33. Hartzell TL, Kuo P, Eberlin KR, Winograd JM, Day CS. The overutilization of resources in patients with acute upper extremity trauma and infection. J Hand Surg Am. 2013 Apr; 38(4):766-73. PMID: 23395105.
    Citations: 3     Fields:    Translation:Humans
  34. Hedegard W, Niell B, Specht M, Winograd J, Rafferty E. Breast reconstruction with a deep inferior epigastric perforator flap: imaging appearances of the normal flap and common complications. AJR Am J Roentgenol. 2013 Jan; 200(1):W75-84. PMID: 23255774.
    Citations: 3     Fields:    Translation:Humans
  35. Coopey SB, Specht MC, Warren L, Smith BL, Winograd JM, Fleischmann K. Use of preoperative paravertebral block decreases length of stay in patients undergoing mastectomy plus immediate reconstruction. Ann Surg Oncol. 2013 Apr; 20(4):1282-6. PMID: 23064793.
    Citations: 6     Fields:    Translation:Humans
  36. Bittner GD, Keating CP, Kane JR, Britt JM, Spaeth CS, Fan JD, Zuzek A, Wilcott RW, Thayer WP, Winograd JM, Gonzalez-Lima F, Schallert T. Rapid, effective, and long-lasting behavioral recovery produced by microsutures, methylene blue, and polyethylene glycol after completely cutting rat sciatic nerves. J Neurosci Res. 2012 May; 90(5):967-80. PMID: 22302646.
    Citations: 14     Fields:    Translation:Animals
  37. Bélanger E, Henry FP, Vallée R, Randolph MA, Kochevar IE, Winograd JM, Lin CP, Côté D. In vivo evaluation of demyelination and remyelination in a nerve crush injury model. Biomed Opt Express. 2011 Sep 01; 2(9):2698-708. PMID: 22091449.
    Citations: 22     
  38. Kpodzo DS, Calderwood MS, Ruchelsman DE, Abramson JS, Piris A, Winograd JM, Kotton CN. Primary subcutaneous Alternaria alternata infection of the hand in an immunocompromised host. Med Mycol. 2011 Jul; 49(5):543-7. PMID: 21299373.
    Citations: 3     Fields:    Translation:HumansAnimals
  39. Grottkau BE, Rebello G, Merlin G, Winograd JM. Coaptive film versus subcuticular suture: comparing skin closure time after posterior spinal instrumented fusion in pediatric patients with spinal deformity. Spine (Phila Pa 1976). 2010 Nov 01; 35(23):2027-9. PMID: 20531072.
    Citations: 2     Fields:    Translation:Humans
  40. Xu YB, Liu J, Li P, Donelan MB, Parrett BM, Winograd JM. The phrenic nerve as a motor nerve donor for facial reanimation with the free latissimus dorsi muscle. J Reconstr Microsurg. 2009 Nov; 25(8):457-63. PMID: 19701878.
    Citations:    Fields:    Translation:Humans
  41. O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Preparation and integration of human amnion nerve conduits using a light-activated technique. Plast Reconstr Surg. 2009 Aug; 124(2):428-37. PMID: 19644257.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  42. Henry FP, Côté D, Randolph MA, Rust EA, Redmond RW, Kochevar IE, Lin CP, Winograd JM. Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg. 2009 Feb; 123(2 Suppl):123S-30S. PMID: 19182671.
    Citations: 21     Fields:    Translation:Animals
  43. Kubo T, Randolph MA, Gröger A, Winograd JM. Embryonic stem cell-derived motor neurons form neuromuscular junctions in vitro and enhance motor functional recovery in vivo. Plast Reconstr Surg. 2009 Feb; 123(2 Suppl):139S-48S. PMID: 19182673.
    Citations: 10     Fields:    Translation:AnimalsCells
  44. Henry FP, Goyal NA, David WS, Wes D, Bujold KE, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Improving electrophysiologic and histologic outcomes by photochemically sealing amnion to the peripheral nerve repair site. Surgery. 2009 Mar; 145(3):313-21. PMID: 19231584.
    Citations: 7     Fields:    Translation:HumansAnimals
  45. Parrett BM, Winograd JM, Lin SJ, Borud LJ, Taghinia A, Lee BT. The posterior tibial artery perforator flap: an alternative to free-flap closure in the comorbid patient. J Reconstr Microsurg. 2009 Feb; 25(2):105-9. PMID: 18924067.
    Citations: 2     Fields:    Translation:Humans
  46. Tucker JD, Montecino R, Winograd JM, Ferraro M, Michelow IC. Pyogenic flexor tenosynovitis associated with Cellulosimicrobium cellulans. J Clin Microbiol. 2008 Dec; 46(12):4106-8. PMID: 18832122.
    Citations: 2     Fields:    Translation:HumansCells
  47. Johnson TS, O'Neill AC, Motarjem PM, Nazzal J, Randolph M, Winograd JM. Tumor formation following murine neural precursor cell transplantation in a rat peripheral nerve injury model. J Reconstr Microsurg. 2008 Nov; 24(8):545-50. PMID: 18819061.
    Citations: 5     Fields:    Translation:AnimalsCells
  48. Parrett BM, Winograd JM, Garfein ES, Lee WP, Hornicek FJ, Austen WG. The vertical and extended rectus abdominis myocutaneous flap for irradiated thigh and groin defects. Plast Reconstr Surg. 2008 Jul; 122(1):171-7. PMID: 18594402.
    Citations: 4     Fields:    Translation:Humans
  49. O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Photochemical sealing improves outcome following peripheral neurorrhaphy. J Surg Res. 2009 Jan; 151(1):33-9. PMID: 18599081.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  50. O'Neill AC, Winograd JM, Zeballos JL, Johnson TS, Randolph MA, Bujold KE, Kochevar IE, Redmond RW. Microvascular anastomosis using a photochemical tissue bonding technique. Lasers Surg Med. 2007 Oct; 39(9):716-22. PMID: 17960755.
    Citations: 8     Fields:    Translation:Animals
  51. Tomita K, Kubo T, Matsuda K, Fujiwara T, Yano K, Winograd JM, Tohyama M, Hosokawa K. The neurotrophin receptor p75NTR in Schwann cells is implicated in remyelination and motor recovery after peripheral nerve injury. Glia. 2007 Aug 15; 55(11):1199-208. PMID: 17600367.
    Citations: 20     Fields:    Translation:AnimalsCells
  52. Johnson TS, O'Neill AC, Motarjem PM, Amann C, Nguyen T, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Photochemical tissue bonding: a promising technique for peripheral nerve repair. J Surg Res. 2007 Dec; 143(2):224-9. PMID: 17543988.
    Citations: 6     Fields:    Translation:AnimalsCells
  53. Craff MN, Zeballos JL, Johnson TS, Ranka MP, Howard R, Motarjem P, Randolph MA, Winograd JM. Embryonic stem cell-derived motor neurons preserve muscle after peripheral nerve injury. Plast Reconstr Surg. 2007 Jan; 119(1):235-45. PMID: 17255679.
    Citations: 6     Fields:    Translation:AnimalsCells
  54. Greene AK, Winograd JM. Images in clinical medicine. Skin redundancy after massive weight loss. N Engl J Med. 2006 Aug 24; 355(8):830. PMID: 16928998.
    Citations: 1     Fields:    Translation:Humans
  55. Bernstein SL, Whitaker D, Winograd J, Brennan JA. An electronic chart prompt to decrease proprietary antibiotic prescription to self-pay patients. Acad Emerg Med. 2005 Mar; 12(3):225-31. PMID: 15741585.
    Citations: 3     Fields:    Translation:Humans
  56. Greene AK, May JW, Winograd JM. Schwannoma of the median nerve: Iatrogenic injury after axillary lymph node biopsy. Surgery. 2005 Mar; 137(3):378-9. PMID: 15746795.
    Citations:    Fields:    Translation:Humans
  57. Johnson TS, Xu JW, Zaporojan VV, Mesa JM, Weinand C, Randolph MA, Bonassar LJ, Winograd JM, Yaremchuk MJ. Integrative repair of cartilage with articular and nonarticular chondrocytes. Tissue Eng. 2004 Sep-Oct; 10(9-10):1308-15. PMID: 15588391.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  58. Schierle C, Winograd JM. Radiation-induced brachial plexopathy: review. Complication without a cure. J Reconstr Microsurg. 2004 Feb; 20(2):149-52. PMID: 15011123.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  59. Walker JC, Brenner MJ, Mackinnon SE, Winograd JM, Hunter DA. Effect of perineurial window size on nerve regeneration, blood-nerve barrier integrity, and functional recovery. J Neurotrauma. 2004 Feb; 21(2):217-27. PMID: 15000762.
    Citations: 4     Fields:    Translation:AnimalsCells
  60. Wiesman IM, Novak CB, Mackinnon SE, Winograd JM. Sensitivity and specificity of clinical testing for carpal tunnel syndrome. Can J Plast Surg. 2003; 11(2):70-2. PMID: 24222987.
    Citations: 3     
  61. Winograd JM, Im MJ, Vander Kolk CA. Enzymatic activation associated with programmed fusion of the posterior interfrontal sutures in rats. Plast Reconstr Surg. 2001 Sep 15; 108(4):927-37. PMID: 11547149.
    Citations:    Fields:    Translation:AnimalsCells
  62. Tung TH, Robertson BR, Winograd JM, Mullick T, Manson PN. Successful distraction osteogenesis across a growing cranial suture without an osteotomy. Plast Reconstr Surg. 1999 Feb; 103(2):362-70. PMID: 9950520.
    Citations: 1     Fields:    Translation:Animals
  63. Winograd JM, Im MJ, Vander Kolk CA. Osteoblastic and osteoclastic activation in coronal sutures undergoing fusion ex vivo. Plast Reconstr Surg. 1997 Oct; 100(5):1103-12. PMID: 9326770.
    Citations:    Fields:    Translation:AnimalsCells
  64. Im MJ, Winograd JM, Manson PN, Vander Kolk CA. Iron-induced rat coronal suture fusion in vitro: the role of redox regulation. J Craniofac Surg. 1997 Jul; 8(4):262-9. PMID: 9482049.
    Citations:    Fields:    Translation:AnimalsCells
  65. Winograd J, Reilly MP, Roe R, Lutz J, Laughner E, Xu X, Hu L, Asakura T, vander Kolk C, Strandberg JD, Semenza GL. Perinatal lethality and multiple craniofacial malformations in MSX2 transgenic mice. Hum Mol Genet. 1997 Mar; 6(3):369-79. PMID: 9147639.
    Citations: 19     Fields:    Translation:HumansAnimals
  66. Winograd J, Palubinskas AJ. Arteriographic diagnosis of appendiceal abscess. Br J Radiol. 1977 Mar; 50(591):229-30. PMID: 849530.
    Citations: 1     Fields:    Translation:Humans
  67. Winograd J, Palubinskas AJ. Arterial-portal venous shunting in cavernous hemangioma of the liver. Radiology. 1977 Feb; 122(2):331-2. PMID: 834871.
    Citations: 6     Fields:    Translation:Humans
  68. Winograd J, Schimmel DH, Palubinskas AJ. The spotted nephrogram of renal scleroderma. AJR Am J Roentgenol. 1976 Apr; 126(4):734-8. PMID: 179339.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.