Harvard Catalyst Profiles

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Shawn Norman Murphy, M.D., Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. OT2OD026553 (SMOLLER, JORDAN W) Mar 1, 2018 - Feb 28, 2023
    NIH
    The New England Precision Medicine Consortium of the All of Us Research Program
    Role: Co-Principal Investigator
  2. R01HG009174 (MURPHY, SHAWN N) Sep 28, 2016 - Aug 31, 2020
    NIH/NHGRI
    Developing i2b2 into a Health Innovation Platform for Clinical Decision Support in the Genomics Era
    Role: Co-Principal Investigator
  3. OT2OD024612 (SMOLLER, JORDAN W) Sep 27, 2016 - Aug 31, 2017
    NIH
    A New England Enrollment Center for PMI Cohort Program
    Role: Co-Principal Investigator
  4. U01HG008685 (WEISS, SCOTT T) Sep 1, 2015 - May 31, 2019
    NIH/NHGRI
    EMERGE PHASE III CLINICAL CENTER AT PARTNERS HEALTHCARE
    Role: Co-Principal Investigator
  5. U54HG007963 (KOHANE, ISAAC S.) Sep 29, 2014 - Aug 31, 2018
    NIH/NHGRI
    Patient-Centered Information Commons
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Estiri H, Murphy SN. Semi-supervised encoding for outlier detection in clinical observation data. Comput Methods Programs Biomed. 2019 Jan 12. PMID: 30658851.
    Citations:    Fields:    
  2. Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T. Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes. Sci Data. 2019 Jan 08; 6:180298. PMID: 30620344.
    Citations:    Fields:    
  3. Klann JG, Phillips LC, Herrick C, Joss MAH, Wagholikar KB, Murphy SN. Web services for data warehouses: OMOP and PCORnet on i2b2. J Am Med Inform Assoc. 2018 Oct 01; 25(10):1331-1338. PMID: 30085008.
    Citations:    Fields:    
  4. Ou Y, Zöllei L, Da X, Retzepi K, Murphy SN, Gerstner ER, Rosen BR, Grant PE, Kalpathy-Cramer J, Gollub RL. Field of View Normalization in Multi-Site Brain MRI. Neuroinformatics. 2018 10; 16(3-4):431-444. PMID: 29353341.
    Citations:    Fields:    
  5. Aronson S, Babb L, Ames D, Gibbs RA, Venner E, Connelly JJ, Marsolo K, Weng C, Williams MS, Hartzler AL, Liang WH, Ralston JD, Devine EB, Murphy S, Chute CG, Caraballo PJ, Kullo IJ, Freimuth RR, Rasmussen LV, Wehbe FH, Peterson JF, Robinson JR, Wiley K, Overby Taylor C. Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example. J Am Med Inform Assoc. 2018 Oct 01; 25(10):1375-1381. PMID: 29860405.
    Citations:    Fields:    
  6. Wagholikar KB, Fischer CM, Goodson A, Herrick CD, Rees M, Toscano E, MacRae CA, Scirica BM, Desai AS, Murphy SN. Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF). J Med Syst. 2018 Sep 25; 42(11):209. PMID: 30255347.
    Citations:    Fields:    Translation:Humans
  7. Cai T, Lin TC, Bond A, Huang J, Kane-Wanger G, Cagan A, Murphy SN, Ananthakrishnan AN, Liao KP. The Association Between Arthralgia and Vedolizumab Using Natural Language Processing. Inflamm Bowel Dis. 2018 Sep 15; 24(10):2242-2246. PMID: 29846617.
    Citations:    Fields:    
  8. Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms. Stroke. 2018 Sep; 49(9):2046-2052. PMID: 30354989.
    Citations:    Fields:    
  9. Visweswaran S, Becich MJ, D'Itri VS, Sendro ER, MacFadden D, Anderson NR, Allen KA, Ranganathan D, Murphy SN, Morrato EH, Pincus HA, Toto R, Firestein GS, Nadler LM, Reis SE. Accrual to Clinical Trials (ACT): A Clinical and Translational Science Award Consortium Network. JAMIA Open. 2018 Oct; 1(2):147-152. PMID: 30474072.
    Citations:    
  10. Wagholikar KB, Dessai P, Sanz J, Mendis ME, Bell DS, Murphy SN. Implementation of informatics for integrating biology and the bedside (i2b2) platform as Docker containers. BMC Med Inform Decis Mak. 2018 07 16; 18(1):66. PMID: 30012140.
    Citations:    Fields:    
  11. Wagholikar KB, Mendis M, Dessai P, Sanz J, Law S, Gilson M, Sanders S, Vangala M, Bell DS, Murphy SN. Automating Installation of the Integrating Biology and the Bedside (i2b2) Platform. Biomed Inform Insights. 2018; 10:1178222618777749. PMID: 29887730.
    Citations:    
  12. Yu Z, Kim SC, Vanni K, Huang J, Desai R, Murphy SN, Solomon DH, Liao KP. Association between inflammation and systolic blood pressure in RA compared to patients without RA. Arthritis Res Ther. 2018 06 01; 20(1):107. PMID: 29855349.
    Citations:    Fields:    
  13. Zhang J, Can A, Mukundan S, Steigner M, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Wang Z, Weiss ST, Du R. Morphological Variables Associated With Ruptured Middle Cerebral Artery Aneurysms. Neurosurgery. 2018 May 30. PMID: 29850834.
    Citations:    Fields:    
  14. Can A, Rudy RF, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms. Stroke. 2018 Jul; 49(7):1747-1750. PMID: 29844027.
    Citations: 1     Fields:    
  15. Raisaro JL, Klann JG, Wagholikar KB, Estiri H, Hubaux JP, Murphy SN. Feasibility of Homomorphic Encryption for Sharing I2B2 Aggregate-Level Data in the Cloud. AMIA Jt Summits Transl Sci Proc. 2018; 2017:176-185. PMID: 29888067.
    Citations:    
  16. Paris N, Mendis M, Daniel C, Murphy S, Tannier X, Zweigenbaum P. i2b2 implemented over SMART-on-FHIR. AMIA Jt Summits Transl Sci Proc. 2018; 2017:369-378. PMID: 29888095.
    Citations:    
  17. Klann JG, Joss M, Shirali R, Natter M, Schneeweiss S, Mandl KD, Murphy SN. The Ad-Hoc Uncertainty Principle of Patient Privacy. AMIA Jt Summits Transl Sci Proc. 2018; 2017:132-138. PMID: 29888058.
    Citations:    
  18. Lin KJ, Glynn RJ, Singer DE, Murphy SN, Lii J, Schneeweiss S. Out-of-system Care and Recording of Patient Characteristics Critical for Comparative Effectiveness Research. Epidemiology. 2018 05; 29(3):356-363. PMID: 29283893.
    Citations:    Fields:    Translation:Humans
  19. Chen CY, Lee PH, Castro VM, Minnier J, Charney AW, Stahl EA, Ruderfer DM, Murphy SN, Gainer V, Cai T, Jones I, Pato CN, Pato MT, Landén M, Sklar P, Perlis RH, Smoller JW. Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records. Transl Psychiatry. 2018 04 18; 8(1):86. PMID: 29666432.
    Citations: 1     Fields:    Translation:Humans
  20. Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Lipid-Lowering Agents and High HDL (High-Density Lipoprotein) Are Inversely Associated With Intracranial Aneurysm Rupture. Stroke. 2018 May; 49(5):1148-1154. PMID: 29622625.
    Citations:    Fields:    
  21. Estiri H, Stephens KA, Klann JG, Murphy SN. Exploring completeness in clinical data research networks with DQe-c. J Am Med Inform Assoc. 2018 01 01; 25(1):17-24. PMID: 29069394.
    Citations:    Fields:    Translation:Humans
  22. Yu S, Ma Y, Gronsbell J, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Liao KP, Cai T. Enabling phenotypic big data with PheNorm. J Am Med Inform Assoc. 2018 01 01; 25(1):54-60. PMID: 29126253.
    Citations: 2     Fields:    Translation:Humans
  23. Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Heroin Use Is Associated with Ruptured Saccular Aneurysms. Transl Stroke Res. 2018 08; 9(4):340-346. PMID: 29103103.
    Citations: 3     Fields:    Translation:Humans
  24. Weber GM, Adams WG, Bernstam EV, Bickel JP, Fox KP, Marsolo K, Raghavan VA, Turchin A, Zhou X, Murphy SN, Mandl KD. Biases introduced by filtering electronic health records for patients with "complete data". J Am Med Inform Assoc. 2017 Nov 01; 24(6):1134-1141. PMID: 29016972.
    Citations: 1     Fields:    Translation:Humans
  25. Lin KJ, Singer DE, Glynn RJ, Murphy SN, Lii J, Schneeweiss S. Identifying Patients With High Data Completeness to Improve Validity of Comparative Effectiveness Research in Electronic Health Records Data. Clin Pharmacol Ther. 2018 May; 103(5):899-905. PMID: 28865143.
    Citations: 1     Fields:    
  26. Can A, Castro VM, Ozdemir YH, Dagen S, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Dammers R, Weiss ST, Du R. Association of intracranial aneurysm rupture with smoking duration, intensity, and cessation. Neurology. 2017 Sep 26; 89(13):1408-1415. PMID: 28855408.
    Citations: 5     Fields:    Translation:Humans
  27. Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage. Transl Stroke Res. 2018 02; 9(1):13-19. PMID: 28752411.
    Citations: 2     Fields:    Translation:Humans
  28. Wagholikar KB, Jain R, Oliveira E, Mandel J, Klann J, Colas R, Patil P, Yadav K, Mandl KD, Carton T, Murphy SN. Evolving Research Data Sharing Networks to Clinical App Sharing Networks. AMIA Jt Summits Transl Sci Proc. 2017; 2017:302-307. PMID: 28815145.
    Citations: 2     
  29. Geva A, Gronsbell JL, Cai T, Cai T, Murphy SN, Lyons JC, Heinz MM, Natter MD, Patibandla N, Bickel J, Mullen MP, Mandl KD. A Computable Phenotype Improves Cohort Ascertainment in a Pediatric Pulmonary Hypertension Registry. J Pediatr. 2017 09; 188:224-231.e5. PMID: 28625502.
    Citations:    
  30. Bernal-Rusiel JL, Rannou N, Gollub RL, Pieper S, Murphy S, Robertson R, Grant PE, Pienaar R. Reusable Client-Side JavaScript Modules for Immersive Web-Based Real-Time Collaborative Neuroimage Visualization. Front Neuroinform. 2017; 11:32. PMID: 28507515.
    Citations:    
  31. Murphy SN, Avillach P, Bellazzi R, Phillips L, Gabetta M, Eran A, McDuffie MT, Kohane IS. Combining clinical and genomics queries using i2b2 - Three methods. PLoS One. 2017; 12(4):e0172187. PMID: 28388645.
    Citations: 1     Fields:    Translation:Humans
  32. Yu S, Chakrabortty A, Liao KP, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Surrogate-assisted feature extraction for high-throughput phenotyping. J Am Med Inform Assoc. 2017 Apr 01; 24(e1):e143-e149. PMID: 27632993.
    Citations: 1     Fields:    Translation:Humans
  33. Ou Y, Zöllei L, Retzepi K, Castro V, Bates SV, Pieper S, Andriole KP, Murphy SN, Gollub RL, Grant PE. Using clinically acquired MRI to construct age-specific ADC atlases: Quantifying spatiotemporal ADC changes from birth to 6-year old. Hum Brain Mapp. 2017 06; 38(6):3052-3068. PMID: 28371107.
    Citations:    Fields:    Translation:Humans
  34. Wagholikar KB, Mandel JC, Klann JG, Wattanasin N, Mendis M, Chute CG, Mandl KD, Murphy SN. SMART-on-FHIR implemented over i2b2. J Am Med Inform Assoc. 2017 03 01; 24(2):398-402. PMID: 27274012.
    Citations: 8     Fields:    Translation:Humans
  35. Castro VM, Dligach D, Finan S, Yu S, Can A, Abd-El-Barr M, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Weiss ST, Du R. Large-scale identification of patients with cerebral aneurysms using natural language processing. Neurology. 2017 Jan 10; 88(2):164-168. PMID: 27927935.
    Citations: 12     Fields:    Translation:Humans
  36. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN. Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2016 Apr; 22(4):880-5. PMID: 26933751.
    Citations: 5     Fields:    Translation:Humans
  37. Gainer VS, Cagan A, Castro VM, Duey S, Ghosh B, Goodson AP, Goryachev S, Metta R, Wang TD, Wattanasin N, Murphy SN. The Biobank Portal for Partners Personalized Medicine: A Query Tool for Working with Consented Biobank Samples, Genotypes, and Phenotypes Using i2b2. J Pers Med. 2016 Feb 26; 6(1). PMID: 26927184; PMCID: PMC4810390.
    Citations: 4     
  38. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2016 07; 14(7):973-9. PMID: 26905907.
    Citations: 5     Fields:    Translation:Humans
  39. Klann JG, Abend A, Raghavan VA, Mandl KD, Murphy SN. Data interchange using i2b2. J Am Med Inform Assoc. 2016 09; 23(5):909-15. PMID: 26911824.
    Citations: 8     Fields:    Translation:Humans
  40. Smoller JW, Karlson EW, Green RC, Kathiresan S, MacArthur DG, Talkowski ME, Murphy SN, Weiss ST. An eMERGE Clinical Center at Partners Personalized Medicine. J Pers Med. 2016 Jan 20; 6(1). PMID: 26805891; PMCID: PMC4810384.
    Citations: 4     
  41. Klann JG, Phillips LC, Turchin A, Weiler S, Mandl KD, Murphy SN. A numerical similarity approach for using retired Current Procedural Terminology (CPT) codes for electronic phenotyping in the Scalable Collaborative Infrastructure for a Learning Health System (SCILHS). BMC Med Inform Decis Mak. 2015 Dec 11; 15:104. PMID: 26655696.
    Citations:    Fields:    Translation:Humans
  42. Klann JG, Pfiffner PB, Natter MD, Conner E, Blazejewski P, Murphy SN, Mandl KD. Supporting Multi-sourced Medication Information in i2b2. AMIA Annu Symp Proc. 2015; 2015:747-55. PMID: 26958210; PMCID: PMC4765563.
    Citations:    Fields:    Translation:Humans
  43. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2015 Nov; 21(11):2507-14. PMID: 26241000.
    Citations: 6     Fields:    Translation:Humans
  44. Castro V, Shen Y, Yu S, Finan S, Pau CT, Gainer V, Keefe CC, Savova G, Murphy SN, Cai T, Welt CK. Identification of subjects with polycystic ovary syndrome using electronic health records. Reprod Biol Endocrinol. 2015 Oct 29; 13:116. PMID: 26510685; PMCID: PMC4625743.
    Citations: 5     Fields:    Translation:Humans
  45. Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T. Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS One. 2015; 10(8):e0136651. PMID: 26301417.
    Citations: 10     Fields:    Translation:Humans
  46. Ou Y, Gollub RL, Retzepi K, Reynolds N, Pienaar R, Pieper S, Murphy SN, Grant PE, Zöllei L. Brain extraction in pediatric ADC maps, toward characterizing neuro-development in multi-platform and multi-institution clinical images. Neuroimage. 2015 Nov 15; 122:246-61. PMID: 26260429.
    Citations: 2     Fields:    Translation:HumansCells
  47. Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J Am Med Inform Assoc. 2015 Sep; 22(5):993-1000. PMID: 25929596; PMCID: PMC4986664.
    Citations: 27     Fields:    Translation:Humans
  48. Liao KP, Cai T, Savova GK, Murphy SN, Karlson EW, Ananthakrishnan AN, Gainer VS, Shaw SY, Xia Z, Szolovits P, Churchill S, Kohane I. Development of phenotype algorithms using electronic medical records and incorporating natural language processing. BMJ. 2015 Apr 24; 350:h1885. PMID: 25911572; PMCID: PMC4707569.
    Citations: 23     Fields:    Translation:Humans
  49. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases. Aliment Pharmacol Ther. 2015 Jun; 41(11):1141-8. PMID: 25864945; PMCID: PMC4420684.
    Citations: 5     Fields:    Translation:Humans
  50. Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, Kiemeney LA, Mariette X, Richard-Miceli C, Canhão H, Fonseca JE, de Vries N, Tak PP, Crusius JB, Nurmohamed MT, Kurreeman F, Mikuls TR, Okada Y, Stahl EA, Larson DE, Deluca TL, O'Laughlin M, Fronick CC, Fulton LL, Kosoy R, Ransom M, Bhangale TR, Ortmann W, Cagan A, Gainer V, Karlson EW, Kohane I, Murphy SN, Martin J, Zhernakova A, Klareskog L, Padyukov L, Worthington J, Mardis ER, Seldin MF, Gregersen PK, Behrens T, Raychaudhuri S, Denny JC, Plenge RM. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. PLoS One. 2015; 10(4):e0122271. PMID: 25849893; PMCID: PMC4388675.
    Citations: 19     Fields:    Translation:Humans
  51. Murphy SN, Herrick C, Wang Y, Wang TD, Sack D, Andriole KP, Wei J, Reynolds N, Plesniak W, Rosen BR, Pieper S, Gollub RL. High throughput tools to access images from clinical archives for research. J Digit Imaging. 2015 Apr; 28(2):194-204. PMID: 25316195.
    Citations: 7     Fields:    Translation:Humans
  52. Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW. Validation of electronic health record phenotyping of bipolar disorder cases and controls. Am J Psychiatry. 2015 Apr; 172(4):363-72. PMID: 25827034.
    Citations: 17     Fields:    Translation:Humans
  53. Klann JG, Mendis M, Phillips LC, Goodson AP, Rocha BH, Goldberg HS, Wattanasin N, Murphy SN. Taking advantage of continuity of care documents to populate a research repository. J Am Med Inform Assoc. 2015 Mar; 22(2):370-9. PMID: 25352566.
    Citations: 7     Fields:    Translation:Humans
  54. Castro VM, McCoy TH, Cagan A, Rosenfield HR, Murphy SN, Churchill SE, Kohane IS, Perlis RH. Stratification of risk for hospital admissions for injury related to fall: cohort study. BMJ. 2014 Oct 24; 349:g5863. PMID: 25954985; PMCID: PMC4208628.
    Citations: 9     Fields:    Translation:Humans
  55. Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Dig Dis Sci. 2015 Feb; 60(2):471-7. PMID: 25213079; PMCID: PMC4304947.
    Citations: 2     Fields:    Translation:Humans
  56. Murphy S, Wilcox A. Mission and Sustainability of Informatics for Integrating Biology and the Bedside (i2b2). EGEMS (Wash DC). 2014; 2(2):1074. PMID: 25848608.
    Citations: 12     
  57. Castro VM, Apperson WK, Gainer VS, Ananthakrishnan AN, Goodson AP, Wang TD, Herrick CD, Murphy SN. Evaluation of matched control algorithms in EHR-based phenotyping studies: a case study of inflammatory bowel disease comorbidities. J Biomed Inform. 2014 Dec; 52:105-11. PMID: 25196084; PMCID: PMC4261034.
    Citations: 5     Fields:    Translation:Humans
  58. Clements CC, Castro VM, Blumenthal SR, Rosenfield HR, Murphy SN, Fava M, Erb JL, Churchill SE, Kaimal AJ, Doyle AE, Robinson EB, Smoller JW, Kohane IS, Perlis RH. Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system. Mol Psychiatry. 2015 Jun; 20(6):727-34. PMID: 25155880; PMCID: PMC4427538.
    Citations: 36     Fields:    Translation:Humans
  59. Blumenthal SR, Castro VM, Clements CC, Rosenfield HR, Murphy SN, Fava M, Weilburg JB, Erb JL, Churchill SE, Kohane IS, Smoller JW, Perlis RH. An electronic health records study of long-term weight gain following antidepressant use. JAMA Psychiatry. 2014 Aug; 71(8):889-96. PMID: 24898363.
    Citations: 22     Fields:    Translation:Humans
  60. Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014 Nov; 133(11):1369-82. PMID: 25062868; PMCID: PMC4185241.
    Citations: 7     Fields:    Translation:Humans
  61. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2015 Feb; 13(2):322-329.e1. PMID: 25041865.
    Citations: 15     Fields:    Translation:Humans
  62. Mandl KD, Kohane IS, McFadden D, Weber GM, Natter M, Mandel J, Schneeweiss S, Weiler S, Klann JG, Bickel J, Adams WG, Ge Y, Zhou X, Perkins J, Marsolo K, Bernstam E, Showalter J, Quarshie A, Ofili E, Hripcsak G, Murphy SN. Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS): architecture. J Am Med Inform Assoc. 2014 Jul-Aug; 21(4):615-20. PMID: 24821734; PMCID: PMC4078286.
    Citations: 22     Fields:    Translation:Humans
  63. Klann JG, Buck MD, Brown J, Hadley M, Elmore R, Weber GM, Murphy SN. Query Health: standards-based, cross-platform population health surveillance. J Am Med Inform Assoc. 2014 Jul-Aug; 21(4):650-6. PMID: 24699371; PMCID: PMC4078284.
    Citations: 14     Fields:    Translation:HumansPHPublic Health
  64. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2014 May; 39(10):1136-42. PMID: 24641590.
    Citations: 21     Fields:    Translation:HumansCells
  65. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Nov; 12(11):1905-10. PMID: 24632349.
    Citations: 6     Fields:    Translation:Humans
  66. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. J Crohns Colitis. 2014 Sep; 8(9):956-63. PMID: 24559536; PMCID: PMC4136996.
    Citations: 11     Fields:    Translation:Humans
  67. O'Dushlaine C, Ripke S, Ruderfer DM, Hamilton SP, Fava M, Iosifescu DV, Kohane IS, Churchill SE, Castro VM, Clements CC, Blumenthal SR, Murphy SN, Smoller JW, Perlis RH. Rare copy number variation in treatment-resistant major depressive disorder. Biol Psychiatry. 2014 Oct 01; 76(7):536-41. PMID: 24529801; PMCID: PMC4104153.
    Citations: 14     Fields:    Translation:HumansCells
  68. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1342-8.e1. PMID: 24407106.
    Citations: 11     Fields:    Translation:Humans
  69. Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):2046-50. PMID: 23925980; PMCID: PMC4060244.
    Citations: 13     Fields:    Translation:Humans
  70. Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL. Modeling disease severity in multiple sclerosis using electronic health records. PLoS One. 2013; 8(11):e78927. PMID: 24244385; PMCID: PMC3823928.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  71. Hripcsak G, Bloomrosen M, FlatelyBrennan P, Chute CG, Cimino J, Detmer DE, Edmunds M, Embi PJ, Goldstein MM, Hammond WE, Keenan GM, Labkoff S, Murphy S, Safran C, Speedie S, Strasberg H, Temple F, Wilcox AB. Health data use, stewardship, and governance: ongoing gaps and challenges: a report from AMIA's 2012 Health Policy Meeting. J Am Med Inform Assoc. 2014 Mar-Apr; 21(2):204-11. PMID: 24169275; PMCID: PMC3932468.
    Citations: 10     Fields:    Translation:Humans
  72. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 May; 12(5):821-7. PMID: 24161349.
    Citations: 26     Fields:    Translation:Humans
  73. Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP. Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease. Inflamm Bowel Dis. 2013 Aug; 19(9):1921-7. PMID: 23751398.
    Citations: 50     Fields:    Translation:Humans
  74. Ananthakrishnan AN, Cai T, Savova G, Cheng SC, Chen P, Perez RG, Gainer VS, Murphy SN, Szolovits P, Xia Z, Shaw S, Churchill S, Karlson EW, Kohane I, Plenge RM, Liao KP. Improving case definition of Crohn's disease and ulcerative colitis in electronic medical records using natural language processing: a novel informatics approach. Inflamm Bowel Dis. 2013 Jun; 19(7):1411-20. PMID: 23567779.
    Citations: 40     Fields:    Translation:Humans
  75. Klann JG, McCoy AB, Wright A, Wattanasin N, Sittig DF, Murphy SN. Health care transformation through collaboration on open-source informatics projects: integrating a medical applications platform, research data repository, and patient summarization. Interact J Med Res. 2013 May 30; 2(1):e11. PMID: 23722634; PMCID: PMC3668611.
    Citations: 9     
  76. Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. 2014 Jun; 73(6):1170-5. PMID: 23716066; PMCID: PMC3815491.
    Citations: 8     Fields:    Translation:Humans
  77. Klann JG, Murphy SN. Computing health quality measures using Informatics for Integrating Biology and the Bedside. J Med Internet Res. 2013 Apr 19; 15(4):e75. PMID: 23603227; PMCID: PMC3636801.
    Citations: 12     Fields:    Translation:Humans
  78. Klann JG, Murphy SN. Supporting the Health Quality Measures Format in i2b2. AMIA Jt Summits Transl Sci Proc. 2013; 2013:124. PMID: 24303250.
    Citations:    
  79. McMurry AJ, Murphy SN, MacFadden D, Weber G, Simons WW, Orechia J, Bickel J, Wattanasin N, Gilbert C, Trevvett P, Churchill S, Kohane IS. SHRINE: enabling nationally scalable multi-site disease studies. PLoS One. 2013; 8(3):e55811. PMID: 23533569.
    Citations: 33     Fields:    Translation:Humans
  80. Liao KP, Kurreeman F, Li G, Duclos G, Murphy S, Guzman R, Cai T, Gupta N, Gainer V, Schur P, Cui J, Denny JC, Szolovits P, Churchill S, Kohane I, Karlson EW, Plenge RM. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. Arthritis Rheum. 2013 Mar; 65(3):571-81. PMID: 23233247; PMCID: PMC3582761.
    Citations: 31     Fields:    Translation:Humans
  81. Castro VM, Clements CC, Murphy SN, Gainer VS, Fava M, Weilburg JB, Erb JL, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH. QT interval and antidepressant use: a cross sectional study of electronic health records. BMJ. 2013 Jan 29; 346:f288. PMID: 23360890; PMCID: PMC3558546.
    Citations: 44     Fields:    Translation:Humans
  82. Ananthakrishnan AN, Gainer VS, Cai T, Perez RG, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw S, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Am J Gastroenterol. 2013 Apr; 108(4):594-601. PMID: 23337479; PMCID: PMC3627544.
    Citations: 16     Fields:    Translation:Humans
  83. Ananthakrishnan AN, Gainer VS, Perez RG, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Aliment Pharmacol Ther. 2013 Feb; 37(4):445-54. PMID: 23289600; PMCID: PMC3552092.
    Citations: 24     Fields:    Translation:Humans
  84. Hoogenboom WS, Perlis RH, Smoller JW, Zeng-Treitler Q, Gainer VS, Murphy SN, Churchill SE, Kohane IS, Shenton ME, Iosifescu DV. Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study. Psychiatry Res. 2013 Mar 30; 211(3):202-13. PMID: 23149041.
    Citations: 6     Fields:    Translation:Humans
  85. Wattanasin N, Porter A, Ubaha S, Mendis M, Phillips L, Mandel J, Ramoni R, Mandl K, Kohane I, Murphy SN. Apps to display patient data, making SMART available in the i2b2 platform. AMIA Annu Symp Proc. 2012; 2012:960-9. PMID: 23304371; PMCID: PMC3540423.
    Citations: 9     Fields:    Translation:Humans
  86. Gallagher PJ, Castro V, Fava M, Weilburg JB, Murphy SN, Gainer VS, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study. Am J Psychiatry. 2012 Oct; 169(10):1065-72. PMID: 23032386; PMCID: PMC3787520.
    Citations: 12     Fields:    Translation:Humans
  87. Bellazzi R, Masseroli M, Murphy S, Shabo A, Romano P. Clinical Bioinformatics: challenges and opportunities. BMC Bioinformatics. 2012; 13 Suppl 14:S1. PMID: 23095472; PMCID: PMC3439676.
    Citations: 3     Fields:    Translation:Humans
  88. Sittig DF, Hazlehurst BL, Brown J, Murphy S, Rosenman M, Tarczy-Hornoch P, Wilcox AB. A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data. Med Care. 2012 Jul; 50 Suppl:S49-59. PMID: 22692259; PMCID: PMC3415281.
    Citations: 16     Fields:    Translation:Humans
  89. Hoogenboom WS, Perlis RH, Smoller JW, Zeng-Treitler Q, Gainer VS, Murphy SN, Churchill SE, Kohane IS, Shenton ME, Iosifescu DV. Limbic system white matter microstructure and long-term treatment outcome in major depressive disorder: a diffusion tensor imaging study using legacy data. World J Biol Psychiatry. 2014 Feb; 15(2):122-34. PMID: 22540406.
    Citations: 9     Fields:    Translation:HumansCells
  90. Kohane IS, McMurry A, Weber G, MacFadden D, Rappaport L, Kunkel L, Bickel J, Wattanasin N, Spence S, Murphy S, Churchill S. The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS One. 2012; 7(4):e33224. PMID: 22511918.
    Citations: 89     Fields:    Translation:Humans
  91. Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Völzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF. A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry. 2013 Apr; 18(4):497-511. PMID: 22472876; PMCID: PMC3837431.
    Citations: 315     Fields:    Translation:Humans
  92. Castro VM, Gallagher PJ, Clements CC, Murphy SN, Gainer VS, Fava M, Weilburg JB, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH. Incident user cohort study of risk for gastrointestinal bleed and stroke in individuals with major depressive disorder treated with antidepressants. BMJ Open. 2012; 2(2):e000544. PMID: 22466034; PMCID: PMC3330255.
    Citations: 12     Fields:    
  93. Mandl KD, Mandel JC, Murphy SN, Bernstam EV, Ramoni RL, Kreda DA, McCoy JM, Adida B, Kohane IS. The SMART Platform: early experience enabling substitutable applications for electronic health records. J Am Med Inform Assoc. 2012 Jul-Aug; 19(4):597-603. PMID: 22427539; PMCID: PMC3384120.
    Citations: 43     Fields:    Translation:Humans
  94. Carroll RJ, Thompson WK, Eyler AE, Mandelin AM, Cai T, Zink RM, Pacheco JA, Boomershine CS, Lasko TA, Xu H, Karlson EW, Perez RG, Gainer VS, Murphy SN, Ruderman EM, Pope RM, Plenge RM, Kho AN, Liao KP, Denny JC. Portability of an algorithm to identify rheumatoid arthritis in electronic health records. J Am Med Inform Assoc. 2012 Jun; 19(e1):e162-9. PMID: 22374935; PMCID: PMC3392871.
    Citations: 81     Fields:    Translation:Humans
  95. Murphy SN, Dubey A, Embi PJ, Harris PA, Richter BG, Turisco F, Weber GM, Tcheng JE, Keogh D. Current state of information technologies for the clinical research enterprise across academic medical centers. Clin Transl Sci. 2012 Jun; 5(3):281-4. PMID: 22686207.
    Citations: 13     Fields:    Translation:Humans
  96. Ananthakrishnan AN, Guzman-Perez R, Gainer V, Cai T, Churchill S, Kohane I, Plenge RM, Murphy S. Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2012 Apr; 35(7):789-95. PMID: 22360370; PMCID: PMC3716251.
    Citations: 20     Fields:    Translation:HumansCells
  97. Kohane IS, Churchill SE, Murphy SN. A translational engine at the national scale: informatics for integrating biology and the bedside. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):181-5. PMID: 22081225; PMCID: PMC3277623.
    Citations: 53     Fields:    Translation:Humans
  98. Murphy SN, Gainer V, Mendis M, Churchill S, Kohane I. Strategies for maintaining patient privacy in i2b2. J Am Med Inform Assoc. 2011 Dec; 18 Suppl 1:i103-8. PMID: 21984588; PMCID: PMC3241166.
    Citations: 18     Fields:    Translation:Humans
  99. Perlis RH, Iosifescu DV, Castro VM, Murphy SN, Gainer VS, Minnier J, Cai T, Goryachev S, Zeng Q, Gallagher PJ, Fava M, Weilburg JB, Churchill SE, Kohane IS, Smoller JW. Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model. Psychol Med. 2012 Jan; 42(1):41-50. PMID: 21682950; PMCID: PMC3837420.
    Citations: 47     Fields:    Translation:Humans
  100. Tatonetti NP, Denny JC, Murphy SN, Fernald GH, Krishnan G, Castro V, Yue P, Tsao PS, Tsau PS, Kohane I, Roden DM, Altman RB. Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels. Clin Pharmacol Ther. 2011 Jul; 90(1):133-42. PMID: 21613990; PMCID: PMC3216673.
    Citations: 73     Fields:    Translation:Humans
  101. Kurreeman F, Liao K, Chibnik L, Hickey B, Stahl E, Gainer V, Li G, Bry L, Mahan S, Ardlie K, Thomson B, Szolovits P, Churchill S, Murphy SN, Cai T, Raychaudhuri S, Kohane I, Karlson E, Plenge RM. Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records. Am J Hum Genet. 2011 Jan 07; 88(1):57-69. PMID: 21211616; PMCID: PMC3014362.
    Citations: 48     Fields:    Translation:Humans
  102. Turchin A, Shubina M, Murphy SN. I am Not Dead Yet: Identification of False-Positive Matches to Death Master File. AMIA Annu Symp Proc. 2010 Nov 13; 2010:807-11. PMID: 21347090; PMCID: PMC3041274.
    Citations:    Fields:    Translation:Humans
  103. Liao KP, Cai T, Gainer V, Goryachev S, Zeng-treitler Q, Raychaudhuri S, Szolovits P, Churchill S, Murphy S, Kohane I, Karlson EW, Plenge RM. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2010 Aug; 62(8):1120-7. PMID: 20235204; PMCID: PMC3121049.
    Citations: 99     Fields:    Translation:Humans
  104. Murphy SN, Weber G, Mendis M, Gainer V, Chueh HC, Churchill S, Kohane I. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc. 2010 Mar-Apr; 17(2):124-30. PMID: 20190053; PMCID: PMC3000779.
    Citations: 227     Fields:    Translation:Humans
  105. Brownstein JS, Murphy SN, Goldfine AB, Grant RW, Sordo M, Gainer V, Colecchi JA, Dubey A, Nathan DM, Glaser JP, Kohane IS. Rapid identification of myocardial infarction risk associated with diabetes medications using electronic medical records. Diabetes Care. 2010 Mar; 33(3):526-31. PMID: 20009093; PMCID: PMC2827502.
    Citations: 31     Fields:    Translation:HumansPHPublic Health
  106. Sordo, M., Ochoa, G., Murphy, S.N. A PSO/ACO approach to knowledge discovery in a pharmacovigilance context. Genetic and Evolutionary Computation Conference - GECCO. 2009; 2679-2684.
  107. Murphy S, Churchill S, Bry L, Chueh H, Weiss S, Lazarus R, Zeng Q, Dubey A, Gainer V, Mendis M, Glaser J, Kohane I. Instrumenting the health care enterprise for discovery research in the genomic era. Genome Res. 2009 Sep; 19(9):1675-81. PMID: 19602638; PMCID: PMC2752136.
    Citations: 66     Fields:    Translation:Humans
  108. Weber GM, Murphy SN, McMurry AJ, Macfadden D, Nigrin DJ, Churchill S, Kohane IS. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc. 2009 Sep-Oct; 16(5):624-30. PMID: 19567788; PMCID: PMC2744712.
    Citations: 94     Fields:    Translation:Humans
  109. Wang, T., Plaisant, C., Quinn, A., Stanchak, R., Murphy, S.N., Shneiderman, B. Aligning temporal data by sentinel events: discovering patterns in electronic health records. ACM Computer-Human Interaction. 2008; 457-466.
  110. Mendis M, Phillips LC, Kuttan R, Pan W, Gainer V, Kohane I, Murphy SN. Integrating outside modules into the i2b2 architecture. AMIA Annu Symp Proc. 2008 Nov 06; 1054. PMID: 18999021.
    Citations: 2     Fields:    
  111. Sordo M, Colecchi J, Dubey A, Dubey AK, Gainer V, Murphy SN. STROBE-based methodology for detection of adverse events across multiple communities. AMIA Annu Symp Proc. 2008 Nov 06; 1144. PMID: 18998965.
    Citations:    Fields:    Translation:Humans
  112. Dubey AK, Gainer V, Murphy SN. Simulated yields of prospective specimen collection from specific patient cohorts using retrospective data from a research patient data repository. AMIA Annu Symp Proc. 2008 Nov 06; 935. PMID: 18999309.
    Citations:    Fields:    
  113. Scheufele EL, Scheufele EL, Dubey A, Dubey AK, Murphy SN. A study of the age attribute in a query tool for a clinical data warehouse. AMIA Annu Symp Proc. 2008 Nov 06; 1123. PMID: 18999019.
    Citations: 1     Fields:    
  114. Wattanasin N, Peng Z, Raine C, Mitchell M, Wang C, Murphy SN. E-facts: business process management in clinical data repositories. AMIA Annu Symp Proc. 2008 Nov 06; 1170. PMID: 18999043.
    Citations: 1     Fields:    
  115. Dinov ID, Rubin D, Lorensen W, Dugan J, Ma J, Murphy S, Kirschner B, Bug W, Sherman M, Floratos A, Kennedy D, Jagadish HV, Schmidt J, Athey B, Califano A, Musen M, Altman R, Kikinis R, Kohane I, Delp S, Parker DS, Toga AW. iTools: a framework for classification, categorization and integration of computational biology resources. PLoS One. 2008 May 28; 3(5):e2265. PMID: 18509477; PMCID: PMC2386255.
    Citations: 12     Fields:    
  116. Keator, D.B., Grethe, J.S., Marcus, D., Ozyurt, B., Gadde, S., Murphy, S.N., Pieper, S., Greve, D., Notestine, R., Bockholt, H.J., Papadopoulos, P. A national neuroimaging collaboratory enabled by The Biomedical Informatics Research Network (BIRN). IEEE Transactions on Information Technology in Biomedicine, Special Bio-Grid edition. 2007; 2(12):162-172.
  117. Weiner, M., Lymon, J., Murphy, S.N. Electronic health records: high-quality electronic data for higher-quality clinical research. Informatics in Primary Care. 2007; 2(15):121-127.
  118. Mendis M, Wattanasin N, Kuttan R, Pan W, Philips L, Hackett K, Gainer V, Chueh HC, Murphy S. Integration of Hive and cell software in the i2b2 architecture. AMIA Annu Symp Proc. 2007 Oct 11; 1048. PMID: 18694146.
    Citations: 5     Fields:    Translation:Humans
  119. Murphy SN, Mendis M, Hackett K, Kuttan R, Pan W, Phillips LC, Gainer V, Berkowicz D, Glaser JP, Kohane I, Chueh HC. Architecture of the open-source clinical research chart from Informatics for Integrating Biology and the Bedside. AMIA Annu Symp Proc. 2007 Oct 11; 548-52. PMID: 18693896; PMCID: PMC2655844.
    Citations: 61     Fields:    Translation:HumansAnimals
  120. Gainer V, Hackett K, Mendis M, Kuttan R, Pan W, Phillips LC, Chueh HC, Murphy S. Using the i2b2 hive for clinical discovery: an example. AMIA Annu Symp Proc. 2007 Oct 11; 959. PMID: 18694059.
    Citations: 9     Fields:    Translation:Humans
  121. Dubey AK, Herrick C, Murphy SN. Mining for associations between categorical data items in a clinical data repository. AMIA Annu Symp Proc. 2007 Oct 11; 945. PMID: 18694045.
    Citations:    Fields:    Translation:Humans
  122. Weiner MG, Lyman JA, Murphy S, Weiner M. Electronic health records: high-quality electronic data for higher-quality clinical research. Inform Prim Care. 2007; 15(2):121-7. PMID: 17877874.
    Citations: 12     Fields:    Translation:Humans
  123. Frank NY, Kho AT, Schatton T, Murphy GF, Molloy MJ, Zhan Q, Ramoni MF, Frank MH, Kohane IS, Gussoni E. Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol. 2006 Oct 09; 175(1):99-110. PMID: 17015616; PMCID: PMC2064502.
    Citations: 27     Fields:    Translation:HumansCells
  124. Zeng QT, Goryachev S, Weiss S, Sordo M, Murphy SN, Lazarus R. Extracting principal diagnosis, co-morbidity and smoking status for asthma research: evaluation of a natural language processing system. BMC Med Inform Decis Mak. 2006 Jul 26; 6:30. PMID: 16872495; PMCID: PMC1553439.
    Citations: 127     Fields:    Translation:Humans
  125. Hackett KL, Kohane IS, Chueh HC, Murphy SN. Mapping tool for maintaining vocabulary relationships. AMIA Annu Symp Proc. 2006; 939. PMID: 17238558; PMCID: PMC1839260.
    Citations:    Fields:    
  126. Murphy SN, Mendis ME, Berkowitz DA, Kohane I, Chueh HC. Integration of clinical and genetic data in the i2b2 architecture. AMIA Annu Symp Proc. 2006; 1040. PMID: 17238659; PMCID: PMC1839291.
    Citations: 41     Fields:    Translation:Humans
  127. Nalichowski R, Keogh D, Chueh HC, Murphy SN. Calculating the benefits of a Research Patient Data Repository. AMIA Annu Symp Proc. 2006; 1044. PMID: 17238663; PMCID: PMC1839563.
    Citations: 62     Fields:    Translation:Humans
  128. Murphy SN, Mendis ME, Grethe JS, Gollub RL, Kennedy D, Rosen BR. A web portal that enables collaborative use of advanced medical image processing and informatics tools through the Biomedical Informatics Research Network (BIRN). AMIA Annu Symp Proc. 2006; 579-83. PMID: 17238407; PMCID: PMC1839506.
    Citations: 9     Fields:    Translation:Humans
  129. Chung J, Murphy S. Concept-value pair extraction from semi-structured clinical narrative: a case study using echocardiogram reports. AMIA Annu Symp Proc. 2005; 131-5. PMID: 16779016; PMCID: PMC1560613.
    Citations: 9     Fields:    Translation:Humans
  130. Murphy SN, Gainer V, Chueh HC. A visual interface designed for novice users to find research patient cohorts in a large biomedical database. AMIA Annu Symp Proc. 2003; 489-93. PMID: 14728221; PMCID: PMC1480150.
    Citations: 18     Fields:    Translation:Humans
  131. Murphy SN, Chueh HC. A security architecture for query tools used to access large biomedical databases. Proc AMIA Symp. 2002; 552-6. PMID: 12463885; PMCID: PMC2244204.
    Citations: 38     Fields:    Translation:Humans
  132. Murphy SN, Barnett GO, Chueh HC. Visual query tool for finding patient cohorts from a clinical data warehouse of the partners HealthCare system Proc AMIA Symp. 2000; 1174. PMID: 11080028.
    Citations: 6     Fields:    
  133. Murphy SN, Morgan MM, Barnett GO, Chueh HC. Optimizing healthcare research data warehouse design through past COSTAR query analysis. Proc AMIA Symp. 1999; 892-6. PMID: 10566489; PMCID: PMC2232518.
    Citations: 18     Fields:    Translation:Humans
  134. Ohno-Machado L, Gennari JH, Murphy SN, Jain NL, Tu SW, Oliver DE, Pattison-Gordon E, Greenes RA, Shortliffe EH, Barnett GO. The guideline interchange format: a model for representing guidelines. J Am Med Inform Assoc. 1998 Jul-Aug; 5(4):357-72. PMID: 9670133; PMCID: PMC61313.
    Citations: 62     Fields:    
  135. Murphy SN, Ng T, Sittig DF, Barnett GO. Using web technology and Java mobile software agents to manage outside referrals. Proc AMIA Symp. 1998; 101-5. PMID: 9929190; PMCID: PMC2232210.
    Citations:    Fields:    
  136. Murphy, S.N., Rabanni, U., Barnett, G.O. Using software agents to maintain autonomous patient registries for clinical research. Journal of the American Informatics Association, Symposium Supplement. 1997; 71-75.
  137. DeEstrada, W.D., Murphy, S.N., Barnett, G.O. Puya: An added-value clinical note retrieval and display system. Journal of the American Informatics Association, Symposium Supplement, 1997. 1997; 509-513.
  138. Murphy SN, Barnett GO. Achieving automated narrative text interpretation using phrases in the electronic medical record. Proc AMIA Annu Fall Symp. 1996; 532-6. PMID: 8947723; PMCID: PMC2233147.
    Citations: 3     Fields:    
  139. van Wingerde FJ, Schindler J, Kilbridge P, Szolovits P, Safran C, Rind D, Murphy S, Barnett GO, Kohane IS. Using HL7 and the World Wide Web for unifying patient data from remote databases. Proc AMIA Annu Fall Symp. 1996; 643-7. PMID: 8947745; PMCID: PMC2233237.
    Citations: 4     Fields:    
  140. Kohane IS, van Wingerde FJ, Fackler JC, Cimino C, Kilbridge P, Murphy S, Chueh H, Rind D, Safran C, Barnett O, Szolovits P. Sharing electronic medical records across multiple heterogeneous and competing institutions. Proc AMIA Annu Fall Symp. 1996; 608-12. PMID: 8947738; PMCID: PMC2233175.
    Citations: 12     Fields:    
  141. Blotner M, Shangold GA, Lee EY, Murphy SN, Miller RJ. Nitrendipine and omega-conotoxin modulate gonadotropin release and gonadotrope [Ca2+]i. Mol Cell Endocrinol. 1990 Jul 09; 71(3):205-16. PMID: 2170211.
    Citations: 1     Fields:    Translation:AnimalsCells
  142. Murphy SN, Miller RJ. Two distinct quisqualate receptors regulate Ca2+ homeostasis in hippocampal neurons in vitro. Mol Pharmacol. 1989 May; 35(5):671-80. PMID: 2566904.
    Citations: 22     Fields:    Translation:AnimalsCells
  143. Murphy SN, Miller RJ. Regulation of Ca++ influx into striatal neurons by kainic acid. J Pharmacol Exp Ther. 1989 Apr; 249(1):184-93. PMID: 2565388.
    Citations: 20     Fields:    Translation:Animals
  144. Murphy SN, Miller RJ. A glutamate receptor regulates Ca2+ mobilization in hippocampal neurons. Proc Natl Acad Sci U S A. 1988 Nov; 85(22):8737-41. PMID: 2903505; PMCID: PMC282536.
    Citations: 27     Fields:    Translation:AnimalsCells
  145. Shangold GA, Murphy SN, Miller RJ. Gonadotropin-releasing hormone-induced Ca2+ transients in single identified gonadotropes require both intracellular Ca2+ mobilization and Ca2+ influx. Proc Natl Acad Sci U S A. 1988 Sep; 85(17):6566-70. PMID: 3045819; PMCID: PMC282014.
    Citations: 18     Fields:    Translation:AnimalsCells
  146. Murphy SN, Thayer SA, Miller RJ. The effects of excitatory amino acids on intracellular calcium in single mouse striatal neurons in vitro. J Neurosci. 1987 Dec; 7(12):4145-58. PMID: 3320284.
    Citations: 33     Fields:    Translation:AnimalsCells
  147. Reynolds IJ, Murphy SN, Miller RJ. 3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine. Proc Natl Acad Sci U S A. 1987 Nov; 84(21):7744-8. PMID: 2823273; PMCID: PMC299377.
    Citations: 41     Fields:    Translation:AnimalsCells
  148. Thayer SA, Murphy SN, Miller RJ. Widespread distribution of dihydropyridine-sensitive calcium channels in the central nervous system. Mol Pharmacol. 1986 Dec; 30(6):505-9. PMID: 2431262.
    Citations: 15     Fields:    Translation:AnimalsCells
  149. Winicur, D.H., Hardwick, J.L., Murphy, S.N. . Spectroscopic studies of the helium-acetylene flame. Combustion and Flame. 1983; 53:93-102.
  150. Miller JD, McKusick VA, Malvaux P, Temtamy S, Salinas C. The 3-M syndrome: a heritable low birthweight dwarfism. Birth Defects Orig Artic Ser. 1975; 11(5):39-47. PMID: 1218233.
    Citations: 18     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.