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Sacha Noelle Uljon, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08CA166227 (ULJON, SACHA N) Jul 18, 2013 - Jul 31, 2018
    The Tribbles-COP1 Complex in Leukemia
    Role: Principal Investigator
  2. F30ES012116 (ULJON, SACHA N) Jul 1, 2003 - Jun 30, 2006
    Structural studies of the RAD6/RAD18 complex
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Caplan DN, Rapalino O, Karaa A, Rosovsky RP, Uljon S. Case 35-2020: A 59-Year-Old Woman with Type 1 Diabetes Mellitus and Obtundation. N Engl J Med. 2020 Nov 12; 383(20):1974-1983. PMID: 33176089.
    Citations:    Fields:    Translation:Humans
  2. Rome KS, Stein SJ, Kurachi M, Petrovic J, Schwartz GW, Mack EA, Uljon S, Wu WW, DeHart AG, McClory SE, Xu L, Gimotty PA, Blacklow SC, Faryabi RB, Wherry EJ, Jordan MS, Pear WS. Trib1 regulates T cell differentiation during chronic infection by restraining the effector program. J Exp Med. 2020 05 04; 217(5). PMID: 32150623.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Uljon SN, Simmons DP, Rudolf JW, Baron JM, Dutta S, McEvoy DS, Murali M, Dighe AS. Validation and Implementation of an Ordering Alert to Improve the Efficiency of Monoclonal Gammopathy Evaluation. Am J Clin Pathol. 2020 02 08; 153(3):396-406. PMID: 31776551.
    Citations:    Fields:    Translation:Humans
  4. Uljon S, Kataria Y, Flood JG. Vortioxetine use may cause false positive immunoassay results for urine methadone. Clin Chim Acta. 2019 Dec; 499:1-3. PMID: 31469980.
    Citations:    Fields:    Translation:HumansCells
  5. Durzynska I, Xu X, Adelmant G, Ficarro SB, Marto JA, Sliz P, Uljon S, Blacklow SC. STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1. Structure. 2017 02 07; 25(2):287-294. PMID: 28089446.
    Citations: 7     Fields:    Translation:HumansCells
  6. Uljon S, Xu X, Durzynska I, Stein S, Adelmant G, Marto JA, Pear WS, Blacklow SC. Structural Basis for Substrate Selectivity of the E3 Ligase COP1. Structure. 2016 05 03; 24(5):687-696. PMID: 27041596.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  7. Tripsas CK, Patterson CJ, Uljon SN, Lindeman NI, Turnbull B, Treon SP. Comparative response assessment by serum immunoglobulin M M-protein and total serum immunoglobulin M after treatment of patients with Waldenström macroglobulinemia. Clin Lymphoma Myeloma Leuk. 2013 Apr; 13(2):250-2. PMID: 23664027.
    Citations:    Fields:    Translation:Humans
  8. Uljon SN, Treon SP, Tripsas CK, Lindeman NI. Challenges with serum protein electrophoresis in assessing progression and clinical response in patients with Waldenström macroglobulinemia. Clin Lymphoma Myeloma Leuk. 2013 Apr; 13(2):247-9. PMID: 23664026.
    Citations: 1     Fields:    Translation:HumansCells
  9. Uljon SN, Richardson PG, Schur PH, Anderson KC, Tanasijevic MJ, Lindeman NI. Serial serum free light chain measurements do not detect changes in disease status earlier than electrophoretic M-spike measurements in patients with intact immunoglobulin myeloma. Clin Chim Acta. 2011 Mar 18; 412(7-8):562-8. PMID: 21144845.
    Citations: 1     Fields:    Translation:Humans
  10. Keeshan K, Bailis W, Dedhia PH, Vega ME, Shestova O, Xu L, Toscano K, Uljon SN, Blacklow SC, Pear WS. Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding. Blood. 2010 Dec 02; 116(23):4948-57. PMID: 20805362.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  11. Dedhia PH, Keeshan K, Uljon S, Xu L, Vega ME, Shestova O, Zaks-Zilberman M, Romany C, Blacklow SC, Pear WS. Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia. Blood. 2010 Aug 26; 116(8):1321-8. PMID: 20410507.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  12. Lone S, Townson SA, Uljon SN, Johnson RE, Brahma A, Nair DT, Prakash S, Prakash L, Aggarwal AK. Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell. 2007 Feb 23; 25(4):601-14. PMID: 17317631.
    Citations: 131     Fields:    Translation:HumansCells
  13. Uljon SN, Johnson RE, Edwards TA, Prakash S, Prakash L, Aggarwal AK. Crystal structure of the catalytic core of human DNA polymerase kappa. Structure. 2004 Aug; 12(8):1395-404. PMID: 15296733.
    Citations: 49     Fields:    Translation:HumansCells
  14. Murphy MP, Uljon SN, Golde TE, Wang R. FAD-linked mutations in presenilin 1 alter the length of Abeta peptides derived from betaAPP transmembrane domain mutants. Biochim Biophys Acta. 2002 Mar 16; 1586(2):199-209. PMID: 11959461.
    Citations: 5     Fields:    Translation:AnimalsCells
  15. Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K. Modulation of A(beta) peptides by estrogen in mouse models. J Neurochem. 2002 Jan; 80(1):191-6. PMID: 11796757.
    Citations: 49     Fields:    Translation:HumansAnimals
  16. Murphy MP, Uljon SN, Fraser PE, Fauq A, Lookingbill HA, Findlay KA, Smith TE, Lewis PA, McLendon DC, Wang R, Golde TE. Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage. J Biol Chem. 2000 Aug 25; 275(34):26277-84. PMID: 10816583.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  17. Jensen M, Hartmann T, Engvall B, Wang R, Uljon SN, Sennvik K, Näslund J, Muehlhauser F, Nordstedt C, Beyreuther K, Lannfelt L. Quantification of Alzheimer amyloid beta peptides ending at residues 40 and 42 by novel ELISA systems. Mol Med. 2000 Apr; 6(4):291-302. PMID: 10949910.
    Citations: 16     Fields:    Translation:HumansCells
  18. Uljon SN, Mazzarelli L, Chait BT, Wang R. Analysis of proteins and peptides directly from biological fluids by immunoprecipitation/mass spectrometry. Methods Mol Biol. 2000; 146:439-52. PMID: 10948517.
    Citations: 7     Fields:    Translation:Animals
  19. McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon S, Wang R, Mann D, Dickson D, Duff K. Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiol Dis. 1999 Aug; 6(4):231-44. PMID: 10448051.
    Citations: 46     Fields:    Translation:Animals
  20. Murphy MP, Hickman LJ, Eckman CB, Uljon SN, Wang R, Golde TE. gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length. J Biol Chem. 1999 Apr 23; 274(17):11914-23. PMID: 10207012.
    Citations: 41     Fields:    Translation:Cells
  21. Lichtenthaler SF, Wang R, Grimm H, Uljon SN, Masters CL, Beyreuther K. Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3053-8. PMID: 10077635.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  22. Banerjee A, Wang R, Uljon SN, Rice PA, Gotschlich EC, Stein DC. Identification of the gene (lgtG) encoding the lipooligosaccharide beta chain synthesizing glucosyl transferase from Neisseria gonorrhoeae. Proc Natl Acad Sci U S A. 1998 Sep 01; 95(18):10872-7. PMID: 9724797.
    Citations: 42     Fields:    Translation:Cells
  23. Groft CM, Uljon SN, Wang R, Werner MH. Structural homology between the Rap30 DNA-binding domain and linker histone H5: implications for preinitiation complex assembly. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9117-22. PMID: 9689043.
    Citations: 25     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.