Harvard Catalyst Profiles

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Sacha Noelle Uljon, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08CA166227 (ULJON, SACHA N) Jul 18, 2013 - Jul 31, 2018
    NIH
    The Tribbles-COP1 Complex in Leukemia
    Role: Principal Investigator
  2. F30ES012116 (ULJON, SACHA N) Jul 1, 2003 - Jun 30, 2006
    NIH
    Structural studies of the RAD6/RAD18 complex
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mahowald G, Khaliq T, Basu S, Griggs D, Siegel M, Leffert L, Bernstein S, Flood JG, Uljon S. Bupivacaine Metabolite Can Interfere with Norfentanyl Measurement by LC-MS/MS. J Appl Lab Med. 2022 06 30; 7(4):854-862. PMID: 35259249.
    Citations:    Fields:    Translation:Humans
  2. Matza MA, Rincon SP, Yucel E, Jorge AM, Singhal AB, Coleman CA, Uljon SN. Case 12-2022: A 41-Year-Old Woman with Transient Ischemic Attack and Mitral Valve Masses. N Engl J Med. 2022 Apr 21; 386(16):1560-1570. PMID: 35443111.
    Citations:    Fields:    Translation:Humans
  3. Uljon S. An Adulterated Urine Buprenorphine Specimen. Prim Care Companion CNS Disord. 2022 Feb 24; 24(2). PMID: 35213940.
    Citations:    Fields:    Translation:Humans
  4. Tolan NV, Terebo T, Chai PR, Erickson TB, Hayes BD, Uljon SN, Petrides AK, Demetriou CA, Melanson SEF. Impact of marijuana legalization on cannabis-related visits to the emergency department. Clin Toxicol (Phila). 2022 May; 60(5):585-595. PMID: 34935567; PMCID: PMC8957546.
    Citations:    Fields:    Translation:HumansAnimals
  5. Mahowald GK, Khaliq TP, Griggs D, O M, Flood JG, Uljon S. Comparison of Oral Fluid and Urine for Detection of Fentanyl Use Using Liquid Chromatography with Tandem Mass Spectrometry. J Appl Lab Med. 2021 11 01; 6(6):1533-1540. PMID: 34327523.
    Citations:    Fields:    Translation:Humans
  6. Yeku OO, Medford AJ, Fenves AZ, Uljon SN. Case 15-2021: A 76-Year-Old Woman with Nausea, Diarrhea, and Acute Kidney Failure. N Engl J Med. 2021 May 20; 384(20):1943-1950. PMID: 34010534.
    Citations:    Fields:    Translation:Humans
  7. Caplan DN, Rapalino O, Karaa A, Rosovsky RP, Uljon S. Case 35-2020: A 59-Year-Old Woman with Type 1 Diabetes Mellitus and Obtundation. N Engl J Med. 2020 Nov 12; 383(20):1974-1983. PMID: 33176089.
    Citations:    Fields:    Translation:Humans
  8. Rome KS, Stein SJ, Kurachi M, Petrovic J, Schwartz GW, Mack EA, Uljon S, Wu WW, DeHart AG, McClory SE, Xu L, Gimotty PA, Blacklow SC, Faryabi RB, Wherry EJ, Jordan MS, Pear WS. Trib1 regulates T cell differentiation during chronic infection by restraining the effector program. J Exp Med. 2020 05 04; 217(5). PMID: 32150623; PMCID: PMC7201917.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  9. Uljon SN, Simmons DP, Rudolf JW, Baron JM, Dutta S, McEvoy DS, Murali M, Dighe AS. Validation and Implementation of an Ordering Alert to Improve the Efficiency of Monoclonal Gammopathy Evaluation. Am J Clin Pathol. 2020 02 08; 153(3):396-406. PMID: 31776551.
    Citations:    Fields:    Translation:Humans
  10. Uljon S, Kataria Y, Flood JG. Vortioxetine use may cause false positive immunoassay results for urine methadone. Clin Chim Acta. 2019 Dec; 499:1-3. PMID: 31469980.
    Citations:    Fields:    Translation:HumansCells
  11. Durzynska I, Xu X, Adelmant G, Ficarro SB, Marto JA, Sliz P, Uljon S, Blacklow SC. STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1. Structure. 2017 02 07; 25(2):287-294. PMID: 28089446; PMCID: PMC5299031.
    Citations: 15     Fields:    Translation:HumansCells
  12. Uljon S, Xu X, Durzynska I, Stein S, Adelmant G, Marto JA, Pear WS, Blacklow SC. Structural Basis for Substrate Selectivity of the E3 Ligase COP1. Structure. 2016 05 03; 24(5):687-696. PMID: 27041596; PMCID: PMC4856590.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  13. Tripsas CK, Patterson CJ, Uljon SN, Lindeman NI, Turnbull B, Treon SP. Comparative response assessment by serum immunoglobulin M M-protein and total serum immunoglobulin M after treatment of patients with Waldenström macroglobulinemia. Clin Lymphoma Myeloma Leuk. 2013 Apr; 13(2):250-2. PMID: 23664027.
    Citations:    Fields:    Translation:Humans
  14. Uljon SN, Treon SP, Tripsas CK, Lindeman NI. Challenges with serum protein electrophoresis in assessing progression and clinical response in patients with Waldenström macroglobulinemia. Clin Lymphoma Myeloma Leuk. 2013 Apr; 13(2):247-9. PMID: 23664026.
    Citations: 1     Fields:    Translation:HumansCells
  15. Uljon SN, Richardson PG, Schur PH, Anderson KC, Tanasijevic MJ, Lindeman NI. Serial serum free light chain measurements do not detect changes in disease status earlier than electrophoretic M-spike measurements in patients with intact immunoglobulin myeloma. Clin Chim Acta. 2011 Mar 18; 412(7-8):562-8. PMID: 21144845.
    Citations: 1     Fields:    Translation:Humans
  16. Keeshan K, Bailis W, Dedhia PH, Vega ME, Shestova O, Xu L, Toscano K, Uljon SN, Blacklow SC, Pear WS. Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding. Blood. 2010 Dec 02; 116(23):4948-57. PMID: 20805362; PMCID: PMC3012589.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  17. Dedhia PH, Keeshan K, Uljon S, Xu L, Vega ME, Shestova O, Zaks-Zilberman M, Romany C, Blacklow SC, Pear WS. Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia. Blood. 2010 Aug 26; 116(8):1321-8. PMID: 20410507; PMCID: PMC2938240.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
  18. Lone S, Townson SA, Uljon SN, Johnson RE, Brahma A, Nair DT, Prakash S, Prakash L, Aggarwal AK. Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell. 2007 Feb 23; 25(4):601-14. PMID: 17317631.
    Citations: 140     Fields:    Translation:HumansCells
  19. Uljon SN, Johnson RE, Edwards TA, Prakash S, Prakash L, Aggarwal AK. Crystal structure of the catalytic core of human DNA polymerase kappa. Structure. 2004 Aug; 12(8):1395-404. PMID: 15296733.
    Citations: 55     Fields:    Translation:HumansCells
  20. Murphy MP, Uljon SN, Golde TE, Wang R. FAD-linked mutations in presenilin 1 alter the length of Abeta peptides derived from betaAPP transmembrane domain mutants. Biochim Biophys Acta. 2002 Mar 16; 1586(2):199-209. PMID: 11959461.
    Citations: 6     Fields:    Translation:AnimalsCells
  21. Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K. Modulation of A(beta) peptides by estrogen in mouse models. J Neurochem. 2002 Jan; 80(1):191-6. PMID: 11796757.
    Citations: 56     Fields:    Translation:HumansAnimals
  22. Murphy MP, Uljon SN, Fraser PE, Fauq A, Lookingbill HA, Findlay KA, Smith TE, Lewis PA, McLendon DC, Wang R, Golde TE. Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage. J Biol Chem. 2000 Aug 25; 275(34):26277-84. PMID: 10816583.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  23. Jensen M, Hartmann T, Engvall B, Wang R, Uljon SN, Sennvik K, Näslund J, Muehlhauser F, Nordstedt C, Beyreuther K, Lannfelt L. Quantification of Alzheimer amyloid beta peptides ending at residues 40 and 42 by novel ELISA systems. Mol Med. 2000 Apr; 6(4):291-302. PMID: 10949910; PMCID: PMC1949952.
    Citations: 20     Fields:    Translation:HumansCells
  24. Uljon SN, Mazzarelli L, Chait BT, Wang R. Analysis of proteins and peptides directly from biological fluids by immunoprecipitation/mass spectrometry. Methods Mol Biol. 2000; 146:439-52. PMID: 10948517.
    Citations: 7     Fields:    Translation:Animals
  25. McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon S, Wang R, Mann D, Dickson D, Duff K. Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiol Dis. 1999 Aug; 6(4):231-44. PMID: 10448051.
    Citations: 49     Fields:    Translation:Animals
  26. Murphy MP, Hickman LJ, Eckman CB, Uljon SN, Wang R, Golde TE. gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length. J Biol Chem. 1999 Apr 23; 274(17):11914-23. PMID: 10207012.
    Citations: 44     Fields:    Translation:Cells
  27. Lichtenthaler SF, Wang R, Grimm H, Uljon SN, Masters CL, Beyreuther K. Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3053-8. PMID: 10077635; PMCID: PMC15893.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  28. Banerjee A, Wang R, Uljon SN, Rice PA, Gotschlich EC, Stein DC. Identification of the gene (lgtG) encoding the lipooligosaccharide beta chain synthesizing glucosyl transferase from Neisseria gonorrhoeae. Proc Natl Acad Sci U S A. 1998 Sep 01; 95(18):10872-7. PMID: 9724797; PMCID: PMC27988.
    Citations: 43     Fields:    Translation:Cells
  29. Groft CM, Uljon SN, Wang R, Werner MH. Structural homology between the Rap30 DNA-binding domain and linker histone H5: implications for preinitiation complex assembly. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9117-22. PMID: 9689043; PMCID: PMC21301.
    Citations: 27     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.