Harvard Catalyst Profiles

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Jun Qi, Ph.D.

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Biography
University of Michigan, Ann Arbor, MIPh.D.09/2006Chemistry

Overview
Our research focuses on exploring novel therapeutic strategies for cancer through a multi-disciplinary approach, including synthetic chemistry, medicinal chemistry, chemical biology, and biology. We study gene regulatory pathways including epigenetic proteins, chromatin modification enzymes, and transcription factors. We start our effort with designing and developing novel small molecule inhibitors. Using chemical probes and chemical biology tools, we seek understanding of the biological relevance of these targets in cancer with the goal of establishing a biological rationale for cancer therapy. Located at Dana-Farber Cancer Institute, our ultimate goal is to develop compounds and strategies that can be used in cancer treatment.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA233601 (DUCKETT, DEREK RONALD ;QI, JUN) Mar 1, 2020 - Feb 28, 2025
    NIH
    Transcriptional and Epigenetic Adaptation as Novel Therapeutic Vulnerabilities for Mantle Cell Lymphoma
    Role: Co-Principal Investigator
  2. R01CA222218 (QI, JUN) Aug 1, 2018 - Jul 31, 2023
    NIH
    EZH2 in cancer biology and novel inhibitors
    Role: Principal Investigator
  3. U01HD076508 (QI, JUN) Sep 26, 2012 - Jun 30, 2017
    NIH
    Selective inhibition of BRDT for male contraception
    Role: Principal Investigator
  4. R01CA176745 (ARMSTRONG, SCOTT A ;QI, JUN) Sep 25, 2012 - May 31, 2023
    NIH
    Targeting DOT1L for Degradation in MLL-rearranged Leukemia
    Role: Co-Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.