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David Joseph Milan, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL132905 (DAS, SAUMYA) Jun 1, 2016 - Mar 31, 2020
    NIH/NHLBI
    Novel Therapy for Long QT Syndrome
    Role: Principal Investigator
  2. R01HL127692 (MILAN, DAVID J) Apr 1, 2015 - Feb 28, 2019
    NIH/NHLBI
    Genetics and Mechanisms of Mitral Valve Prolapse
    Role: Principal Investigator
  3. R01HL109004 (MILAN, DAVID J) Sep 5, 2011 - Jun 30, 2014
    NIH/NHLBI
    High Throughput Screening for Chemical Modifiers of Long QT Syndrome
    Role: Principal Investigator
  4. R21HL096009 (MILAN, DAVID J) Feb 3, 2010 - Jan 31, 2012
    NIH/NHLBI
    Electrical Silencing of the Pulmonary Veins
    Role: Principal Investigator
  5. R21DA026982 (MILAN, DAVID J) Sep 30, 2009 - Aug 31, 2013
    NIH/NIDA
    The Genetic Basis of Novel Loci Influencing Myocardial Repolarization
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Toomer KA, Yu M, Fulmer D, Guo L, Moore KS, Moore R, Drayton KD, Glover J, Peterson N, Ramos-Ortiz S, Drohan A, Catching BJ, Stairley R, Wessels A, Lipschutz JH, Delling FN, Jeunemaitre X, Dina C, Collins RL, Brand H, Talkowski ME, Del Monte F, Mukherjee R, Awgulewitsch A, Body S, Hardiman G, Hazard ES, da Silveira WA, Wang B, Leyne M, Durst R, Markwald RR, Le Scouarnec S, Hagege A, Le Tourneau T, Kohl P, Rog-Zielinska EA, Ellinor PT, Levine RA, Milan DJ, Schott JJ, Bouatia-Naji N, Slaugenhaupt SA, Norris RA. Primary cilia defects causing mitral valve prolapse. Sci Transl Med. 2019 05 22; 11(493). PMID: 31118289.
    Citations:    
  2. Yu M, Georges A, Tucker NR, Kyryachenko S, Toomer K, Schott JJ, Delling FN, Fernandez-Friera L, Solis J, Ellinor PT, Levine RA, Slaugenhaupt SA, Hagège AA, Dina C, Jeunemaitre X, Milan DJ, Norris RA, Bouatia-Naji N. Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse. Circ Genom Precis Med. 2019 05; 12(5):e002497. PMID: 31112420.
    Citations:    
  3. Hulsmans M, Aguirre AD, Bonner MD, Bapat A, Cremer S, Iwamoto Y, King KR, Swirski FK, Milan DJ, Weissleder R, Nahrendorf M. A Miniaturized, Programmable Pacemaker for Long-Term Studies in the Mouse. Circ Res. 2018 11 09; 123(11):1208-1219. PMID: 30571465.
    Citations:    Fields:    
  4. Hu D, Linders A, Yamak A, Correia C, Kijlstra JD, Garakani A, Xiao L, Milan DJ, van der Meer P, Serra M, Alves PM, Domian IJ. Metabolic Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes by Inhibition of HIF1a and LDHA. Circ Res. 2018 10 12; 123(9):1066-1079. PMID: 30355156.
    Citations:    Fields:    
  5. Macri V, Brody JA, Arking DE, Hucker WJ, Yin X, Lin H, Mills RW, Sinner MF, Lubitz SA, Liu CT, Morrison AC, Alonso A, Li N, Fedorov VV, Janssen PM, Bis JC, Heckbert SR, Dolmatova EV, Lumley T, Sitlani CM, Cupples LA, Pulit SL, Newton-Cheh C, Barnard J, Smith JD, Van Wagoner DR, Chung MK, Vlahakes GJ, O'Donnell CJ, Rotter JI, Margulies KB, Morley MP, Cappola TP, Benjamin EJ, Muzny D, Gibbs RA, Jackson RD, Magnani JW, Herndon CN, Rich SS, Psaty BM, Milan DJ, Boerwinkle E, Mohler PJ, Sotoodehnia N, Ellinor PT. Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction. Circ Genom Precis Med. 2018 05; 11(5):e001663. PMID: 29752399.
    Citations:    
  6. Le Tourneau T, Le Scouarnec S, Cueff C, Bernstein D, Aalberts JJJ, Lecointe S, Mérot J, Bernstein JA, Oomen T, Dina C, Karakachoff M, Desal H, Al Habash O, Delling FN, Capoulade R, Suurmeijer AJH, Milan D, Norris RA, Markwald R, Aikawa E, Slaugenhaupt SA, Jeunemaitre X, Hagège A, Roussel JC, Trochu JN, Levine RA, Kyndt F, Probst V, Le Marec H, Schott JJ. New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study. Eur Heart J. 2018 04 14; 39(15):1269-1277. PMID: 29020406.
    Citations: 1     Fields:    
  7. Dagres N, Chao TF, Fenelon G, Aguinaga L, Benhayon D, Benjamin EJ, Bunch TJ, Chen LY, Chen SA, Darrieux F, de Paola A, Fauchier L, Goette A, Kalman J, Kalra L, Kim YH, Lane DA, Lip GYH, Lubitz SA, Márquez MF, Potpara T, Pozzer DL, Ruskin JN, Savelieva I, Teo WS, Tse HF, Verma A, Zhang S, Chung MK, Bautista-Vargas WF, Chiang CE, Cuesta A, Dan GA, Frankel DS, Guo Y, Hatala R, Lee YS, Murakawa Y, Pellegrini CN, Pinho C, Milan DJ, Morin DP, Nadalin E, Ntaios G, Prabhu MA, Proietti M, Rivard L, Valentino M, Shantsila A. European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: What is the best practice? J Arrhythm. 2018 04; 34(2):99-123. PMID: 29657586.
    Citations:    
  8. Musunuru K, Sheikh F, Gupta RM, Houser SR, Maher KO, Milan DJ, Terzic A, Wu JC. Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2018 01; 11(1):e000043. PMID: 29874173.
    Citations: 1     
  9. Tucker NR, McLellan MA, Hu D, Ye J, Parsons VA, Mills RW, Clauss S, Dolmatova E, Shea MA, Milan DJ, Scott NS, Lindsay M, Lubitz SA, Domian IJ, Stone JR, Lin H, Ellinor PT. Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy. Circ Cardiovasc Genet. 2017 Dec; 10(6). PMID: 29212899.
    Citations: 1     Fields:    Translation:HumansCells
  10. Leyton-Mange JS, Hucker WJ, Mihatov N, Reynolds M, Albert C, Lubitz SA, Milan DJ. Experience With Wearable Cardioverter-Defibrillators at 2 Academic Medical Centers. JACC Clin Electrophysiol. 2018 02; 4(2):231-239. PMID: 29749943.
    Citations: 1     
  11. Milan D. The Com-PLEC-sity of Atrial Fibrillation Genetics. J Am Coll Cardiol. 2017 10 24; 70(17):2169-2170. PMID: 29050565.
    Citations:    Fields:    
  12. Tucker NR, Dolmatova EV, Lin H, Cooper RR, Ye J, Hucker WJ, Jameson HS, Parsons VA, Weng LC, Mills RW, Sinner MF, Imakaev M, Leyton-Mange J, Vlahakes G, Benjamin EJ, Lunetta KL, Lubitz SA, Mirny L, Milan DJ, Ellinor PT. Diminished PRRX1 Expression Is Associated With Increased Risk of Atrial Fibrillation and Shortening of the Cardiac Action Potential. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 28974514.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  13. Lam PY, Mendu SK, Mills RW, Zheng B, Padilla H, Milan DJ, Desai BN, Peterson RT. A high-conductance chemo-optogenetic system based on the vertebrate channel Trpa1b. Sci Rep. 2017 09 19; 7(1):11839. PMID: 28928472.
    Citations:    Fields:    
  14. Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017 04 20; 169(3):510-522.e20. PMID: 28431249.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  15. Bezzerides VJ, Zhang A, Xiao L, Simonson B, Khedkar SA, Baba S, Ottaviano F, Lynch S, Hessler K, Rigby AC, Milan D, Das S, Rosenzweig A. Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders. Sci Rep. 2017 03 23; 7(1):346. PMID: 28336914.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  16. Kiando SR, Tucker NR, Castro-Vega LJ, Katz A, D'Escamard V, Tréard C, Fraher D, Albuisson J, Kadian-Dodov D, Ye Z, Austin E, Yang ML, Hunker K, Barlassina C, Cusi D, Galan P, Empana JP, Jouven X, Gimenez-Roqueplo AP, Bruneval P, Hyun Kim ES, Olin JW, Gornik HL, Azizi M, Plouin PF, Ellinor PT, Kullo IJ, Milan DJ, Ganesh SK, Boutouyrie P, Kovacic JC, Jeunemaitre X, Bouatia-Naji N. PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance. PLoS Genet. 2016 Oct; 12(10):e1006367. PMID: 27792790.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  17. Tucker NR, Mahida S, Ye J, Abraham EJ, Mina JA, Parsons VA, McLellan MA, Shea MA, Hanley A, Benjamin EJ, Milan DJ, Lin H, Ellinor PT. Gain-of-function mutations in GATA6 lead to atrial fibrillation. Heart Rhythm. 2017 02; 14(2):284-291. PMID: 27756709.
    Citations: 1     Fields:    Translation:Humans
  18. Kiando S, Tucker N, Castro-Vega L, Cusi D, Galan P, J-P E, Olin J, Gornik H, Plouin PF, Kullo I, Milan D, Ganesh S, Boutouyrie P, Kovacic J, Jeunemaitre X, Bouatia-Naji N. [OP.7C.04] GENETIC ASSOCIATION STUDY IDENTIFIES COMMON VARIATION IN PHACTR1 TO ASSOCIATE WITH FIBROMUSCULAR DYSPLASIA. J Hypertens. 2016 Sep; 34 Suppl 2:e91. PMID: 27508836.
    Citations:    
  19. Milan DJ, Saul JP, Somberg JC, Molnar J. Efficacy of Intravenous and Oral Sotalol in Pharmacologic Conversion of Atrial Fibrillation: A Systematic Review and Meta-Analysis. Cardiology. 2017; 136(1):52-60. PMID: 27554842.
    Citations: 4     Fields:    Translation:Humans
  20. Wang X, Tucker NR, Rizki G, Mills R, Krijger PH, de Wit E, Subramanian V, Bartell E, Nguyen XX, Ye J, Leyton-Mange J, Dolmatova EV, van der Harst P, de Laat W, Ellinor PT, Newton-Cheh C, Milan DJ, Kellis M, Boyer LA. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. Elife. 2016 05 10; 5. PMID: 27162171.
    Citations: 9     Fields:    Translation:HumansAnimals
  21. Sroubek J, Probst V, Mazzanti A, Delise P, Hevia JC, Ohkubo K, Zorzi A, Champagne J, Kostopoulou A, Yin X, Napolitano C, Milan DJ, Wilde A, Sacher F, Borggrefe M, Ellinor PT, Theodorakis G, Nault I, Corrado D, Watanabe I, Antzelevitch C, Allocca G, Priori SG, Lubitz SA. Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis. Circulation. 2016 Feb 16; 133(7):622-30. PMID: 26797467.
    Citations: 15     Fields:    Translation:Humans
  22. Kiando S, Tucker N, Katz A, Tréard C, Desca-Mard V, Castro-Vega L, Barlasina C, Cusi D, Galan P, Empana J, Olin J, Gornik H, Plouin P, Kullo I, Milan D, Ganesh S, Boutouyrie P, Kovacic J, Jeunemaitre X, Bouatia-Naji N. CO-43: Genetic study identifies common variation in phactr1 to associate with fibromuscular dysplasia. Ann Cardiol Angeiol (Paris). 2015 Dec; 64 Suppl 1:S20. PMID: 26877297.
    Citations:    
  23. Guyette JP, Charest JM, Mills RW, Jank BJ, Moser PT, Gilpin SE, Gershlak JR, Okamoto T, Gonzalez G, Milan DJ, Gaudette GR, Ott HC. Bioengineering Human Myocardium on Native Extracellular Matrix. Circ Res. 2016 Jan 08; 118(1):56-72. PMID: 26503464.
    Citations: 25     Fields:    Translation:HumansCells
  24. Martin PS, Kloesel B, Norris RA, Lindsay M, Milan D, Body SC. Embryonic Development of the Bicuspid Aortic Valve. J Cardiovasc Dev Dis. 2015 Dec; 2(4):248-272. PMID: 28529942.
    Citations: 6     
  25. Winterfield JR, Milan DJ. Dexamethasone suppresses long QT phenotype in patient with acute promyelocytic leukemia treated with arsenic. HeartRhythm Case Rep. 2016 Jul; 2(4):280-282. PMID: 28491690.
    Citations:    
  26. Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA, Jeunemaitre X. Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nat Genet. 2015 Oct; 47(10):1206-11. PMID: 26301497.
    Citations: 15     Fields:    Translation:HumansAnimals
  27. Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA. Mutations in DCHS1 cause mitral valve prolapse. Nature. 2015 Sep 03; 525(7567):109-13. PMID: 26258302.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  28. Acha MR, Keaney JJ, Lubitz SA, Milan DJ, Mansour M, Heist KE, Ptaszek LM, Singh JP, Blendea D, Mela T. Increased perforation risk with an MRI-conditional pacing lead: a single-center study. Pacing Clin Electrophysiol. 2015 Mar; 38(3):334-42. PMID: 25469809.
    Citations: 7     Fields:    Translation:Humans
  29. Leyton-Mange JS, Milan DJ. Pluripotent stem cells as a platform for cardiac arrhythmia drug screening. Curr Treat Options Cardiovasc Med. 2014 Sep; 16(9):334. PMID: 25074263.
    Citations: 2     
  30. Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, Macfarlane PW, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden AG, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR, Benjamin EJ, Milan DJ, Melander O, Heckbert SR, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT. Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation. 2014 Oct 07; 130(15):1225-35. PMID: 25124494.
    Citations: 45     Fields:    Translation:HumansAnimals
  31. Lundby A, Rossin EJ, Steffensen AB, Acha MR, Newton-Cheh C, Pfeufer A, Lynch SN, Olesen SP, Brunak S, Ellinor PT, Jukema JW, Trompet S, Ford I, Macfarlane PW, Krijthe BP, Hofman A, Uitterlinden AG, Stricker BH, Nathoe HM, Spiering W, Daly MJ, Asselbergs FW, van der Harst P, Milan DJ, de Bakker PI, Lage K, Olsen JV. Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. Nat Methods. 2014 Aug; 11(8):868-74. PMID: 24952909.
    Citations: 14     Fields:    Translation:HumansAnimals
  32. Macri V, Mahida SN, Zhang ML, Sinner MF, Dolmatova EV, Tucker NR, McLellan M, Shea MA, Milan DJ, Lunetta KL, Benjamin EJ, Ellinor PT. A novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation. Heart Rhythm. 2014 Jun; 11(6):1055-1062. PMID: 24607718.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  33. Leyton-Mange JS, Mills RW, Macri VS, Jang MY, Butte FN, Ellinor PT, Milan DJ. Rapid cellular phenotyping of human pluripotent stem cell-derived cardiomyocytes using a genetically encoded fluorescent voltage sensor. Stem Cell Reports. 2014 Feb 11; 2(2):163-70. PMID: 24527390.
    Citations: 34     Fields:    Translation:HumansCells
  34. Milan D, Singh JP. Device implantation and complications: time to recalibrate our expectations? Eur Heart J. 2014 May; 35(18):1167-8. PMID: 24482308.
    Citations:    Fields:    Translation:Humans
  35. Mahida S, Mills RW, Tucker NR, Simonson B, Macri V, Lemoine MD, Das S, Milan DJ, Ellinor PT. Overexpression of KCNN3 results in sudden cardiac death. Cardiovasc Res. 2014 Feb 01; 101(2):326-34. PMID: 24296650.
    Citations: 13     Fields:    Translation:AnimalsCells
  36. Rav Acha M, Milan D. Who should receive the subcutaneous implanted defibrillator?: Timing is not right to replace the transvenous implantable cardioverter defibrillator. Circ Arrhythm Electrophysiol. 2013 Dec; 6(6):1246-51; discussion 1251. PMID: 24347600.
    Citations: 5     Fields:    Translation:Humans
  37. Parashar S, Chan K, Milan D, Grafstein E, Palmer AK, Rhodes C, Montaner JS, Hogg RS. The impact of unstable housing on emergency department use in a cohort of HIV-positive people in a Canadian setting. AIDS Care. 2014 Jan; 26(1):53-64. PMID: 23656484.
    Citations: 2     Fields:    Translation:Humans
  38. den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, Müller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp S, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Jarvelin MR, Jula A, Kähönen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimäki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widen E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L, Erdmann J, Thompson JR, Pfeufer A, Sotoodehnia N, Newton-Cheh C, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Jun; 45(6):621-31. PMID: 23583979.
    Citations: 67     Fields:    Translation:HumansAnimals
  39. Kolpa HJ, Peal DS, Lynch SN, Giokas AC, Ghatak S, Misra S, Norris RA, Macrae CA, Markwald RR, Ellinor P, Bischoff J, Milan DJ. miR-21 represses Pdcd4 during cardiac valvulogenesis. Development. 2013 May; 140(10):2172-80. PMID: 23578931.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  40. Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, Peterson RT. Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol. 2013 Apr; 9(4):257-63. PMID: 23396078.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  41. Wu SM, Milan DJ. Reprogramming the beat: kicking it up a notch. Circulation. 2012 Aug 28; 126(9):1009-11. PMID: 22837161.
    Citations:    Fields:    Translation:AnimalsCells
  42. Chen JX, Krane M, Deutsch MA, Wang L, Rav-Acha M, Gregoire S, Engels MC, Rajarajan K, Karra R, Abel ED, Wu JC, Milan D, Wu SM. Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. Circ Res. 2012 Jun 22; 111(1):50-5. PMID: 22581928.
    Citations: 97     Fields:    Translation:HumansAnimalsCells
  43. Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Müller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dörr M, Ozaki K, Roberts JD, Smith JG, Pfeufer A, Sinner MF, Lohman K, Ding J, Smith NL, Smith JD, Rienstra M, Rice KM, Van Wagoner DR, Magnani JW, Wakili R, Clauss S, Rotter JI, Steinbeck G, Launer LJ, Davies RW, Borkovich M, Harris TB, Lin H, Völker U, Völzke H, Milan DJ, Hofman A, Boerwinkle E, Chen LY, Soliman EZ, Voight BF, Li G, Chakravarti A, Kubo M, Tedrow UB, Rose LM, Ridker PM, Conen D, Tsunoda T, Furukawa T, Sotoodehnia N, Xu S, Kamatani N, Levy D, Nakamura Y, Parvez B, Mahida S, Furie KL, Rosand J, Muhammad R, Psaty BM, Meitinger T, Perz S, Wichmann HE, Witteman JC, Kao WH, Kathiresan S, Roden DM, Uitterlinden AG, Rivadeneira F, McKnight B, Sjögren M, Newman AB, Liu Y, Gollob MH, Melander O, Tanaka T, Stricker BH, Felix SB, Alonso A, Darbar D, Barnard J, Chasman DI, Heckbert SR, Benjamin EJ, Gudnason V, Kääb S. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012 Apr 29; 44(6):670-5. PMID: 22544366.
    Citations: 184     Fields:    Translation:Humans
  44. Ozcan C, Rottman JN, Heist EK, Guy ML, Ellinor PT, Singh J, Milan DJ, Danik SB, Barrett CD, Mansour M, Ruskin JN, Mela T. Unpredictable battery depletion of St Jude Atlas II and Atlas+ II HF implantable cardioverter-defibrillators. Heart Rhythm. 2012 May; 9(5):717-20. PMID: 22172318.
    Citations:    Fields:    Translation:Humans
  45. Robic A, Larzul C, Grindflek E, Chevillon P, Hofer A, Fève K, Iannuccelli N, Milan D, Prunier A, Riquet J. Molecular characterization of the porcine TEAD3 (TEF-5) gene: examination of a promoter mutation as the causal mutation of a quantitative trait loci affecting the androstenone level in boar fat. J Anim Breed Genet. 2012 Aug; 129(4):325-35. PMID: 22775265.
    Citations:    Fields:    Translation:AnimalsCells
  46. Milan DJ, Acha MR. Recovery of myocardial tissue from extracted leads. Heart Rhythm. 2012 Mar; 9(3):405-6. PMID: 22063082.
    Citations:    Fields:    Translation:HumansCells
  47. Gondret F, Riquet J, Tacher S, Demars J, Sanchez MP, Billon Y, Robic A, Bidanel JP, Milan D. Towards candidate genes affecting body fatness at the SSC7 QTL by expression analyses. J Anim Breed Genet. 2012 Aug; 129(4):316-24. PMID: 22775264.
    Citations: 3     Fields:    Translation:AnimalsCells
  48. Rosendo A, Iannuccelli N, Gilbert H, Riquet J, Billon Y, Amigues Y, Milan D, Bidanel JP. Microsatellite mapping of quantitative trait loci affecting female reproductive tract characteristics in Meishan x Large White F(2) pigs. J Anim Sci. 2012 Jan; 90(1):37-44. PMID: 21948608.
    Citations: 1     Fields:    Translation:AnimalsCells
  49. Peal DS, Lynch SN, Milan DJ. Patterning and development of the atrioventricular canal in zebrafish. J Cardiovasc Transl Res. 2011 Dec; 4(6):720-6. PMID: 21948390.
    Citations: 6     Fields:    Translation:AnimalsCells
  50. Singh S, Mushtaq U, Holm-Hansen C, Milan D, Cheung A, Watts N. The importance of climate change to health. Lancet. 2011 Jul 02; 378(9785):29-30. PMID: 21724036.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  51. Koruth JS, Heist EK, Milan DJ. Pacemaker tachycardia with changing rates. Pacing Clin Electrophysiol. 2010 Dec; 33(12):1552-3. PMID: 20561228.
    Citations:    Fields:    Translation:Humans
  52. Loutfy MR, Genebat M, Moore D, Raboud J, Chan K, Antoniou T, Milan D, Shen A, Klein MB, Cooper C, Machouf N, Rourke SB, Rachlis A, Tsoukas C, Montaner JS, Walmsley SL, Smieja M, Bayoumi A, Mills E, Hogg RS. A CD4+ cell count <200 cells per cubic millimeter at 2 years after initiation of combination antiretroviral therapy is associated with increased mortality in HIV-infected individuals with viral suppression. J Acquir Immune Defic Syndr. 2010 Dec; 55(4):451-9. PMID: 21105259.
    Citations: 12     Fields:    Translation:HumansCells
  53. Mahida S, Lubitz SA, Rienstra M, Milan DJ, Ellinor PT. Monogenic atrial fibrillation as pathophysiological paradigms. Cardiovasc Res. 2011 Mar 01; 89(4):692-700. PMID: 21123219.
    Citations: 18     Fields:    Translation:Humans
  54. Thuillier R, Renard C, Rogel-Gaillard C, Demars J, Milan D, Forestier L, Ouldmoulene A, Goujon JM, Badet L, Hauet T. Effect of polyethylene glycol-based preservation solutions on graft injury in experimental kidney transplantation. Br J Surg. 2011 Mar; 98(3):368-78. PMID: 21254010.
    Citations: 6     Fields:    Translation:AnimalsCells
  55. Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ. Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen. Circulation. 2011 Jan 04; 123(1):23-30. PMID: 21098441.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  56. Peal DS, Peterson RT, Milan D. Small molecule screening in zebrafish. J Cardiovasc Transl Res. 2010 Oct; 3(5):454-60. PMID: 20680709.
    Citations: 20     Fields:    Translation:AnimalsCells
  57. Mills RW, Milan DJ. TRPM4-linked isolated cardiac conduction defects: bad trafficking causes electrical gridlock. Circ Cardiovasc Genet. 2010 Aug; 3(4):311-3. PMID: 20716750.
    Citations: 2     Fields:    Translation:HumansCells
  58. Milan DJ, Melman YF, Ellinor PT. Rare ion channel polymorphisms: separating signal from noise. Heart Rhythm. 2010 Jul; 7(7):920-1. PMID: 20451667.
    Citations: 1     Fields:    Translation:Humans
  59. Milan DJ, Lubitz SA, Kääb S, Ellinor PT. Genome-wide association studies in cardiac electrophysiology: recent discoveries and implications for clinical practice. Heart Rhythm. 2010 Aug; 7(8):1141-8. PMID: 20423731.
    Citations: 8     Fields:    Translation:Humans
  60. Beinart R, Ruskin J, Milan D. The genetics of conduction disease. Heart Fail Clin. 2010 Apr; 6(2):201-14. PMID: 20347788.
    Citations: 2     Fields:    Translation:Humans
  61. Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, Soliman EZ, Rice KM, Van Wagoner DR, Beckmann BM, van Noord C, Wang K, Ehret GB, Rotter JI, Hazen SL, Steinbeck G, Smith AV, Launer LJ, Harris TB, Makino S, Nelis M, Milan DJ, Perz S, Esko T, Köttgen A, Moebus S, Newton-Cheh C, Li M, Möhlenkamp S, Wang TJ, Kao WH, Vasan RS, Nöthen MM, MacRae CA, Stricker BH, Hofman A, Uitterlinden AG, Levy D, Boerwinkle E, Metspalu A, Topol EJ, Chakravarti A, Gudnason V, Psaty BM, Roden DM, Meitinger T, Wichmann HE, Witteman JC, Barnard J, Arking DE, Benjamin EJ, Heckbert SR, Kääb S. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar; 42(3):240-4. PMID: 20173747.
    Citations: 180     Fields:    Translation:Humans
  62. Palmer AK, Klein MB, Raboud J, Cooper C, Hosein S, Loutfy M, Machouf N, Montaner J, Rourke SB, Smieja M, Tsoukas C, Yip B, Milan D, Hogg RS. Cohort profile: the Canadian Observational Cohort collaboration. Int J Epidemiol. 2011 Feb; 40(1):25-32. PMID: 20157000.
    Citations: 17     Fields:    Translation:Humans
  63. Peal DS, Burns CG, Macrae CA, Milan D. Chondroitin sulfate expression is required for cardiac atrioventricular canal formation. Dev Dyn. 2009 Dec; 238(12):3103-10. PMID: 19890913.
    Citations: 17     Fields:    Translation:Animals
  64. Aleong RG, Singh SM, Levinson JR, Milan DJ. Catecholamine challenge unmasking high-risk features in the Wolff-Parkinson-White syndrome. Europace. 2009 Oct; 11(10):1396-8. PMID: 19654129.
    Citations:    Fields:    Translation:Humans
  65. Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, Sanna S, Arking DE, Amsterdam AH, Sabeh KM, Mably JD, Rosenbaum DS, Peterson RT, Chakravarti A, Kääb S, Roden DM, MacRae CA. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation. 2009 Aug 18; 120(7):553-9. PMID: 19652097.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  66. Ma J, Ren J, Guo Y, Duan Y, Ding N, Zhou L, Li L, Yan X, Yang K, Huang L, Song Y, Xie J, Milan D, Huang L. Genome-wide identification of quantitative trait loci for carcass composition and meat quality in a large-scale White Duroc x Chinese Erhualian resource population. Anim Genet. 2009 Oct; 40(5):637-47. PMID: 19397518.
    Citations: 22     Fields:    Translation:Animals
  67. Ma J, Qi W, Ren D, Duan Y, Qiao R, Guo Y, Yang Z, Li L, Milan D, Ren J, Huang L. A genome scan for quantitative trait loci affecting three ear traits in a White Duroc x Chinese Erhualian resource population. Anim Genet. 2009 Aug; 40(4):463-7. PMID: 19392826.
    Citations: 5     Fields:    Translation:AnimalsCells
  68. Ren J, Tang H, Yan X, Huang X, Zhang B, Ji H, Yang B, Milan D, Huang L. A pig-human comparative RH map comprising 20 genes on pig chromosome 13q41 that harbours the ETEC F4ac receptor locus. J Anim Breed Genet. 2009 Feb; 126(1):30-6. PMID: 19207927.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  69. Milan DJ, Macrae CA. Zebrafish genetic models for arrhythmia. Prog Biophys Mol Biol. 2008 Oct-Nov; 98(2-3):301-8. PMID: 19351520.
    Citations: 10     Fields:    Translation:Animals
  70. Danik SB, Mansour M, Heist EK, Ellinor P, Milan D, Singh J, Das S, Reddy V, D'Avila A, Ruskin JN, Mela T. Timing of delayed perforation with the St. Jude Riata lead: a single-center experience and a review of the literature. Heart Rhythm. 2008 Dec; 5(12):1667-72. PMID: 19084802.
    Citations: 5     Fields:    Translation:Humans
  71. David J. Milan, MD, Jeff R. Winterfield, MD and Calum A. MacRae, MD, PhD. A Zebrafish Pharmacogenetic Screen Reveals an Integrin-associated Network Regulating Repolarization. Heart Rhythm Society Featured Poster. 2008.
  72. Ellinor PT, Milan DJ. Polymorphisms and atrial fibrillation: sorting the wheat from the chaff. Eur Heart J. 2008 Apr; 29(7):843-5. PMID: 18310053.
    Citations:    Fields:    Translation:Humans
  73. Aleong RG, Milan DJ, Ellinor PT. The diagnosis and treatment of cardiac ion channelopathies: congenital long QT syndrome and Brugada syndrome. Curr Treat Options Cardiovasc Med. 2007 Oct; 9(5):364-71. PMID: 17897565.
    Citations: 1     
  74. Ellinor PT, Nam EG, Shea MA, Milan DJ, Ruskin JN, MacRae CA. Cardiac sodium channel mutation in atrial fibrillation. Heart Rhythm. 2008 Jan; 5(1):99-105. PMID: 18088563.
    Citations: 47     Fields:    Translation:Humans
  75. Heist EK, Chevalier J, Holmvang G, Singh JP, Ellinor PT, Milan DJ, D'Avila A, Mela T, Ruskin JN, Mansour M. Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation. J Interv Card Electrophysiol. 2006 Oct; 17(1):21-7. PMID: 17252200.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  76. Danik SB, Mansour M, Singh J, Reddy VY, Ellinor PT, Milan D, Heist EK, d'Avila A, Ruskin JN, Mela T. Increased incidence of subacute lead perforation noted with one implantable cardioverter-defibrillator. Heart Rhythm. 2007 Apr; 4(4):439-42. PMID: 17399630.
    Citations: 11     Fields:    Translation:Humans
  77. Morisson M, Denis M, Milan D, Klopp C, Leroux S, Bardes S, Pitel F, Vignoles F, Gérus M, Fillon V, Douaud M, Vignal A. The chicken RH map: current state of progress and microchromosome mapping. Cytogenet Genome Res. 2007; 117(1-4):14-21. PMID: 17675840.
    Citations: 8     Fields:    Translation:AnimalsCells
  78. D.J. Milan, I.L. Jones, A.H. Amsterdam, D.S. Rosenbaum, D. Roden, C.A. MacRae . A Pharmacogenetic Screen for Modifiers of Drug Induced QT Prolongation Reveals 15 Novel Genes. American Heart Association, 2007 Scientific Sessions. 2007.
  79. SanCristobal M, Chevalet C, Peleman J, Heuven H, Brugmans B, van Schriek M, Joosten R, Rattink AP, Harlizius B, Groenen MA, Amigues Y, Boscher MY, Russell G, Law A, Davoli R, Russo V, Dèsautés C, Alderson L, Fimland E, Bagga M, Delgado JV, Vega-Pla JL, Martinez AM, Ramos M, Glodek P, Meyer JN, Gandini G, Matassino D, Siggens K, Laval G, Archibald A, Milan D, Hammond K, Cardellino R, Haley C, Plastow G. Genetic diversity in European pigs utilizing amplified fragment length polymorphism markers. Anim Genet. 2006 Jun; 37(3):232-8. PMID: 16734682.
    Citations: 3     Fields:    Translation:AnimalsCells
  80. SanCristobal M, Chevalet C, Haley CS, Joosten R, Rattink AP, Harlizius B, Groenen MA, Amigues Y, Boscher MY, Russell G, Law A, Davoli R, Russo V, Désautés C, Alderson L, Fimland E, Bagga M, Delgado JV, Vega-Pla JL, Martinez AM, Ramos M, Glodek P, Meyer JN, Gandini GC, Matassino D, Plastow GS, Siggens KW, Laval G, Archibald AL, Milan D, Hammond K, Cardellino R. Genetic diversity within and between European pig breeds using microsatellite markers. Anim Genet. 2006 Jun; 37(3):189-98. PMID: 16734675.
    Citations: 17     Fields:    Translation:AnimalsCells
  81. David J. Milan, MD, Andrea C. Giokas, BS and Calum A. MacRae, MD, PhD. Notch Signaling Plays a Critical Role in Cardiac Conduction System Specification. Heart Rhythm Society, 2006 Scientific Sessions. 2006.
  82. David J. Milan, MD, Andrea C. Giokas, BS and Calum A. MacRae, MD. Genetic Knockdown of Troponin T Results in Electromechanical Uncoupling without the Proarrhythmia of 2,4 Butanedione Monoxime. Heart Rhythm Society 2006 Scientific Sessions. 2006.
  83. Ho IC, Milan DJ, Mansour MC, Mela T, Guy ML, Ruskin JN, Ellinor PT. Fungal infection of implantable cardioverter-defibrillators: case series of five patients managed over 22 years. Heart Rhythm. 2006 Aug; 3(8):919-23. PMID: 16876740.
    Citations:    Fields:    Translation:HumansAnimals
  84. Du HL, Chen J, Cui JX, Zhang YS, Yerle M, Milan D, Zhang XQ. Radiation hybrid mapping and sequence analysis of 21 genes on porcine chromosome 15. Anim Genet. 2006 Apr; 37(2):181-3. PMID: 16573537.
    Citations: 1     Fields:    Translation:AnimalsCells
  85. Sanchez MP, Riquet J, Iannuccelli N, Gogué J, Billon Y, Demeure O, Caritez JC, Burgaud G, Fève K, Bonnet M, Péry C, Lagant H, Le Roy P, Bidanel JP, Milan D. Effects of quantitative trait loci on chromosomes 1, 2, 4, and 7 on growth, carcass, and meat quality traits in backcross Meishan x Large White pigs. J Anim Sci. 2006 Mar; 84(3):526-37. PMID: 16478944.
    Citations:    
  86. Milan DJ, Jones IL, Ellinor PT, MacRae CA. In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation. Am J Physiol Heart Circ Physiol. 2006 Jul; 291(1):H269-73. PMID: 16489111.
    Citations: 53     Fields:    Translation:Animals
  87. Milan DJ, Giokas AC, Serluca FC, Peterson RT, MacRae CA. Notch1b and neuregulin are required for specification of central cardiac conduction tissue. Development. 2006 Mar; 133(6):1125-32. PMID: 16481353.
    Citations: 61     Fields:    Translation:AnimalsCells
  88. Ian Jones, David J Milan, Patrick T Ellinor, Calum MacRae. Zebrafish as a Model System for Drug Mediated QT Prolongation. American Heart Association Scientific Sessions Program. 2005.
  89. Judith L. Meadows and David J. Milan. Complete Heart Block as the Primary Presentation of Thyrotoxicosis. American Heart Association, Scientific Sessions. 2005.
  90. Demeure O, Pomp D, Milan D, Rothschild MF, Tuggle CK. Mapping of 443 porcine EST improves the comparative maps for SSC1 and SSC7 with the human genome. Anim Genet. 2005 Oct; 36(5):381-9. PMID: 16167980.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  91. Pérez-Enciso M, Mercadé A, Bidanel JP, Geldermann H, Cepica S, Bartenschlager H, Varona L, Milan D, Folch JM. Large-scale, multibreed, multitrait analyses of quantitative trait loci experiments: the case of porcine X chromosome. J Anim Sci. 2005 Oct; 83(10):2289-96. PMID: 16160038.
    Citations: 7     Fields:    Translation:AnimalsCells
  92. Burns CG, Milan DJ, Grande EJ, Rottbauer W, MacRae CA, Fishman MC. High-throughput assay for small molecules that modulate zebrafish embryonic heart rate. Nat Chem Biol. 2005 Oct; 1(5):263-4. PMID: 16408054.
    Citations: 112     Fields:    Translation:Animals
  93. Demeure O, Sanchez MP, Riquet J, Iannuccelli N, Demars J, Fève K, Kernaleguen L, Gogué J, Billon Y, Caritez JC, Milan D, Bidanel JP. Exclusion of the swine leukocyte antigens as candidate region and reduction of the position interval for the Sus scrofa chromosome 7 QTL affecting growth and fatness. J Anim Sci. 2005 Sep; 83(9):1979-87. PMID: 16100052.
    Citations: 4     Fields:    Translation:AnimalsCells
  94. Milan DJ, MacRae CA. Animal models for arrhythmias. Cardiovasc Res. 2005 Aug 15; 67(3):426-37. PMID: 16009355.
    Citations: 19     Fields:    Translation:Animals
  95. Milan, D; Giokas, A; Serluca, F; Peterson, R; MacRae, C. Neuregulin but not Endothelin Signaling is required for Atrioventricular Conduction Tissue Development. Heart Rhythm Society. 2005.
  96. Milan D, Keane D. Increase in frequency of conduction over accessory atrio-ventricular pathways upon transition from atrial fibrillation to atrial flutter. Int J Cardiol. 2005 Feb 28; 98(3):513-5. PMID: 15708191.
    Citations:    Fields:    Translation:Humans
  97. Lefaucheur L, Milan D, Ecolan P, Le Callennec C. Myosin heavy chain composition of different skeletal muscles in Large White and Meishan pigs. J Anim Sci. 2004 Jul; 82(7):1931-41. PMID: 15309939.
    Citations: 23     Fields:    Translation:AnimalsCells
  98. Peterson RT, Shaw SY, Peterson TA, Milan DJ, Zhong TP, Schreiber SL, MacRae CA, Fishman MC. Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol. 2004 May; 22(5):595-9. PMID: 15097998.
    Citations: 114     Fields:    Translation:AnimalsCells
  99. Demeure O, Liaubet L, Riquet J, Milan D. Determination of PRKAG1 coding sequence and mapping of PRKAG1 and PRKAG2 relatively to porcine back fat thickness QTL. Anim Genet. 2004 Apr; 35(2):123-5. PMID: 15025572.
    Citations: 2     Fields:    Translation:AnimalsCells
  100. Stanley Y Shaw, Travis A Peterson, David J Milan, Tao P Zhong, Calum A MacRae, Stuart L Schreiber, Mark C Fishman, Randall T Peterson. Discovery of a Novel Pro-Vasculogenic Small Molecule via a Chemical Genetic Screen for Suppressors of Zebrafish Gridlock Mutants . Circulation. 2003; 108(21):2723-a.
  101. Ellinor PT, Milan DJ, MacRae CA. Risk stratification in the long-QT syndrome. N Engl J Med. 2003 Aug 28; 349(9):908-9; author reply 908-9. PMID: 12944579.
    Citations:    Fields:    Translation:Humans
  102. Randall T. Peterson, Calum A. MacRae, Stanley Y. Shaw, David J. Milan, Travis A. Peterson, Mark C. Fishman. Methods for Treating Vascular Diseases. 2003.
  103. Beaumont C, Protais J, Pitel F, Leveque G, Malo D, Lantier F, Plisson-Petit F, Colin P, Protais M, Le Roy P, Elsen JM, Milan D, Lantier I, Neau A, Salvat G, Vignal A. Effect of two candidate genes on the Salmonella carrier state in fowl. Poult Sci. 2003 May; 82(5):721-6. PMID: 12762392.
    Citations: 6     Fields:    Translation:AnimalsCells
  104. Milan DJ, Peterson TA, Ruskin JN, Peterson RT, MacRae CA. Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation. 2003 Mar 18; 107(10):1355-8. PMID: 12642353.
    Citations: 94     Fields:    Translation:Animals
  105. Quintanilla R, Demeure O, Bidanel JP, Milan D, Iannuccelli N, Amigues Y, Gruand J, Renard C, Chevalet C, Bonneau M. Detection of quantitative trait loci for fat androstenone levels in pigs. J Anim Sci. 2003 Feb; 81(2):385-94. PMID: 12643481.
    Citations: 15     Fields:    Translation:Animals
  106. Robic A, Faraut T, Iannuccelli N, Lahbib-Mansais Y, Cantegrel V, Alexander L, Milan D. A new contribution to the integration of human and porcine genome maps: 623 new points of homology. Cytogenet Genome Res. 2003; 102(1-4):100-8. PMID: 14970687.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  107. Milan, David Joseph,M.D.; Burns, C. Geoffrey, Ph.D.; Peterson, Randall T., Ph.D.; Macrae, Calum Archibald,M.B.,Ch.B. Patent of Zebrafish Cardiotoxicity Assay. 2002.
  108. Yerle M, Pinton P, Delcros C, Arnal N, Milan D, Robic A. Generation and characterization of a 12,000-rad radiation hybrid panel for fine mapping in pig. Cytogenet Genome Res. 2002; 97(3-4):219-28. PMID: 12438716.
    Citations: 14     Fields:    Translation:AnimalsCells
  109. Bidanel JP, Milan D, Iannuccelli N, Amigues Y, Boscher MY, Bourgeois F, Caritez JC, Gruand J, Le Roy P, Lagant H, Quintanilla R, Renard C, Gellin J, Ollivier L, Chevalet C. Detection of quantitative trait loci for growth and fatness in pigs. Genet Sel Evol. 2001 May-Jun; 33(3):289-309. PMID: 11403749.
    Citations: 47     Fields:    Translation:Animals
  110. Jeon JT, Amarger V, Rogel-Gaillard C, Robic A, Bongcam-Rudloff E, Paul S, Looft C, Milan D, Chardon P, Andersson L. Comparative analysis of a BAC contig of the porcine RN region and the human transcript map: implications for the cloning of trait loci. Genomics. 2001 Mar 15; 72(3):297-303. PMID: 11401445.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  111. Lahbib-Mansais Y, Leroux S, Milan D, Yerle M, Robic A, Jiang Z, André C, Gellin J. Comparative mapping between humans and pigs: localization of 58 anchorage markers (TOASTs) by use of porcine somatic cell and radiation hybrid panels. Mamm Genome. 2000 Dec; 11(12):1098-106. PMID: 11130978.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  112. Walling GA, Visscher PM, Andersson L, Rothschild MF, Wang L, Moser G, Groenen MA, Bidanel JP, Cepica S, Archibald AL, Geldermann H, de Koning DJ, Milan D, Haley CS. Combined analyses of data from quantitative trait loci mapping studies. Chromosome 4 effects on porcine growth and fatness. Genetics. 2000 Jul; 155(3):1369-78. PMID: 10880495.
    Citations: 35     Fields:    Translation:AnimalsCells
  113. Milan D, Jeon JT, Looft C, Amarger V, Robic A, Thelander M, Rogel-Gaillard C, Paul S, Iannuccelli N, Rask L, Ronne H, Lundström K, Reinsch N, Gellin J, Kalm E, Roy PL, Chardon P, Andersson L. A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle. Science. 2000 May 19; 288(5469):1248-51. PMID: 10818001.
    Citations: 118     Fields:    Translation:HumansAnimalsCells
  114. Laval G, Iannuccelli N, Legault C, Milan D, Groenen MA, Giuffra E, Andersson L, Nissen PH, Jørgensen CB, Beeckmann P, Geldermann H, Foulley JL, Chevalet C, Ollivier L. Genetic diversity of eleven European pig breeds. Genet Sel Evol. 2000 Mar-Apr; 32(2):187-203. PMID: 14736401.
    Citations: 16     Fields:    
  115. Lahbib-Mansais Y, Barbosa A, Yerle M, Parma P, Milan D, Pailhoux E, Gellin J, Cotinot C. Mapping in pig of genes involved in sexual differentiation: AMH, WT1, FTZF1, SOX2, SOX9, AHC, and placental and embryonic CYP19. Cytogenet Cell Genet. 1997; 76(1-2):109-14. PMID: 9154138.
    Citations: 4     Fields:    Translation:AnimalsCells
  116. Nelson PH, Carr SF, Devens BH, Eugui EM, Franco F, Gonzalez C, Hawley RC, Loughhead DG, Milan DJ, Papp E, Patterson JW, Rouhafza S, Sjogren EB, Smith DB, Stephenson RA, Talamas FX, Waltos AM, Weikert RJ, Wu JC. Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid. J Med Chem. 1996 Oct 11; 39(21):4181-96. PMID: 8863796.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  117. Shibasaki F, Price ER, Milan D, McKeon F. Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4. Nature. 1996 Jul 25; 382(6589):370-3. PMID: 8684469.
    Citations: 113     Fields:    Translation:HumansAnimalsCells
  118. Milan D, McKeon FD. . Molecular Basis for Immunosuppression of Cyclosporin A and FK-506. 1996.
  119. Avogaro A, Crepaldi C, Piarulli F, Milan D, Valerio A, Pavan P, Sacerdoti D, Calabrò A, Macdonald I, Crepaldi G, Scognamiglio R, Tiengo A. The hemodynamic abnormalities in short-term insulin deficiency: the role of prostaglandin inhibition. Diabetes. 1996 May; 45(5):602-9. PMID: 8621010.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  120. Yerle M, Echard G, Robic A, Mairal A, Dubut-Fontana C, Riquet J, Pinton P, Milan D, Lahbib-Mansais Y, Gellin J. A somatic cell hybrid panel for pig regional gene mapping characterized by molecular cytogenetics. Cytogenet Cell Genet. 1996; 73(3):194-202. PMID: 8697807.
    Citations: 47     Fields:    Translation:AnimalsCells
  121. Clouscard C, Beaudry P, Elsen JM, Milan D, Dussaucy M, Bounneau C, Schelcher F, Chatelain J, Launay JM, Laplanche JL. Different allelic effects of the codons 136 and 171 of the prion protein gene in sheep with natural scrapie. J Gen Virol. 1995 Aug; 76 ( Pt 8):2097-101. PMID: 7636494.
    Citations: 44     Fields:    Translation:AnimalsCells
  122. Milan D, Griffith J, Su M, Price ER, McKeon F. The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation. Cell. 1994 Nov 04; 79(3):437-47. PMID: 7525078.
    Citations: 25     Fields:    Translation:HumansCells
  123. Yerle M, Schmitz A, Milan D, Chaput B, Monteagudo L, Vaiman M, Frelat G, Gellin J. Accurate characterization of porcine bivariate flow karyotype by PCR and fluorescence in situ hybridization. Genomics. 1993 Apr; 16(1):97-103. PMID: 8486390.
    Citations: 21     Fields:    Translation:AnimalsCells
  124. Calabrò A, Piarulli F, Milan D, Rossi A, Coscetti G, Crepaldi G. Clinical assessment of low molecular weight heparin effects in peripheral vascular disease. Angiology. 1993 Mar; 44(3):188-95. PMID: 8382899.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  125. Ban J, Portetelle D, Altaner C, Horion B, Milan D, Krchnak V, Burny A, Kettmann R. Isolation and characterization of a 2.3-kilobase-pair cDNA fragment encoding the binding domain of the bovine leukemia virus cell receptor. J Virol. 1993 Feb; 67(2):1050-7. PMID: 8380453.
    Citations: 25     Fields:    Translation:Cells
  126. Milan D, Yerle M, Schmitz A, Chaput B, Vaiman M, Frelat G, Gellin J. A PCR-based method to amplify DNA with random primers: determining the chromosomal content of porcine flow-karyotype peaks by chromosome painting. Cytogenet Cell Genet. 1993; 62(2-3):139-41. PMID: 8428513.
    Citations: 7     Fields:    Translation:AnimalsCells
  127. Milan D, Nicolas JF. Activator-dependent and activator-independent defective recombinant retroviruses from bovine leukemia virus. J Virol. 1991 Apr; 65(4):1938-45. PMID: 1848312.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.