Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Carolyn Yung Ho, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL155568 (HO, CAROLYN Y) Sep 1, 2021 - Aug 31, 2025
    Hypertrophic Cardiomyopathy: Understanding the Heterogeneity of Disease Expression and Outcomes
    Role: Principal Investigator
  2. P50HL112349 (HO, CAROLYN Y) May 15, 2012 - Jul 31, 2021
    Using Genetics For Early Phenotyping & Prevention of Hypertrophic Cardiomyopathy
    Role: Principal Investigator
  3. P20HL101408 (HO, CAROLYN Y) Apr 1, 2010 - Mar 31, 2013
    Using Genetics for Early Phenotyping &Prevention of Hypertrophic Cardiomyopathy
    Role: Principal Investigator
  4. K23HL078901 (HO, CAROLYN Y) Sep 26, 2005 - Jul 31, 2011
    Diagnostic and Treatment Strategies for Preclinical HCM
    Role: Principal Investigator
  5. F32HL068466 (HO, CAROLYN Y) Jul 1, 2002 - Jun 30, 2004
    Diastolic Function in Hypertrophic Cardiomyopathy
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Argirò A, Ho C, Day SM, van der Velden J, Cerbai E, Saberi S, Tardiff JC, Lakdawala NK, Olivotto I. Sex-Related Differences in Genetic Cardiomyopathies. J Am Heart Assoc. 2022 May 03; 11(9):e024947. PMID: 35470690.
    Citations:    Fields:    Translation:Humans
  2. Norrish G, Qu C, Field E, Cervi E, Khraiche D, Klaassen S, Ojala TH, Sinagra G, Yamazawa H, Marrone C, Popoiu A, Centeno F, Schouvey S, Olivotto I, Day SM, Colan S, Rossano J, Wittekind SG, Saberi S, Russell M, Helms A, Ingles J, Semsarian C, Elliott PM, Ho CY, Omar RZ, Kaski JP. External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy. Eur J Prev Cardiol. 2022 03 30; 29(4):678-686. PMID: 34718528.
    Citations:    Fields:    Translation:Humans
  3. Hegde SM, Lester SJ, Solomon SD, Michels M, Elliott PM, Nagueh SF, Choudhury L, Zemanek D, Zwas DR, Jacoby D, Wang A, Ho CY, Li W, Sehnert AJ, Olivotto I, Abraham TP. Effect of Mavacamten on Echocardiographic Features in Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy. J Am Coll Cardiol. 2021 12 21; 78(25):2518-2532. PMID: 34915982.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  4. Nauffal V, Marstrand P, Han L, Parikh VN, Helms AS, Ingles J, Jacoby D, Lakdawala NK, Kapur S, Michels M, Owens AT, Ashley EA, Pereira AC, Rossano JW, Saberi S, Semsarian C, Ware JS, Wittekind SG, Day S, Olivotto I, Ho CY. Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy. Eur Heart J. 2021 10 07; 42(38):3932-3944. PMID: 34491319.
    Citations:    Fields:    Translation:HumansPHPublic Health
  5. Ho CY, Day SM, Axelsson A, Russell MW, Zahka K, Lever HM, Pereira AC, Colan SD, Margossian R, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Bundgaard H, Benson L, Mestroni L, Taylor MRG, Patel AR, Wilmot I, Thrush P, Vargas JD, Soslow JH, Becker JR, Seidman CE, Lakdawala NK, Cirino AL, Burns KM, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E. Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial. Nat Med. 2021 10; 27(10):1818-1824. PMID: 34556856.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  6. de Marvao A, McGurk KA, Zheng SL, Thanaj M, Bai W, Duan J, Biffi C, Mazzarotto F, Statton B, Dawes TJW, Savioli N, Halliday BP, Xu X, Buchan RJ, Baksi AJ, Quinlan M, Tokarczuk P, Tayal U, Francis C, Whiffin N, Theotokis PI, Zhang X, Jang M, Berry A, Pantazis A, Barton PJR, Rueckert D, Prasad SK, Walsh R, Ho CY, Cook SA, Ware JS, O'Regan DP. Phenotypic Expression and Outcomes in Individuals With Rare Genetic Variants of Hypertrophic Cardiomyopathy. J Am Coll Cardiol. 2021 09 14; 78(11):1097-1110. PMID: 34503678.
    Citations: 2     Fields:    Translation:HumansCells
  7. Kramer CM, DiMarco JP, Kolm P, Ho CY, Desai MY, Kwong RY, Dolman SF, Desvigne-Nickens P, Geller N, Kim DY, Maron MS, Appelbaum E, Jerosch-Herold M, Friedrich MG, Schulz-Menger J, Piechnik SK, Mahmod M, Jacoby D, White J, Chiribiri A, Helms A, Choudhury L, Michels M, Bradlow W, Salerno M, Dawson DK, Weinsaft JW, Berry C, Nagueh SF, Buccarelli-Ducci C, Owens A, Casadei B, Watkins H, Weintraub WS, Neubauer S. Predictors of Major Atrial Fibrillation Endpoints in the National Heart, Lung, and Blood Institute HCMR. JACC Clin Electrophysiol. 2021 11; 7(11):1376-1386. PMID: 34217663.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  8. Captur G, Manisty CH, Raman B, Marchi A, Wong TC, Ariga R, Bhuva A, Ormondroyd E, Lobascio I, Camaioni C, Loizos S, Bonsu-Ofori J, Turer A, Zaha VG, Augutsto JB, Davies RH, Taylor AJ, Nasis A, Al-Mallah MH, Valentin S, Perez de Arenaza D, Patel V, Westwood M, Petersen SE, Li C, Tang L, Nakamori S, Nezafat R, Kwong RY, Ho CY, Fraser AG, Watkins H, Elliott PM, Neubauer S, Lloyd G, Olivotto I, Nihoyannopoulos P, Moon JC. Maximal Wall Thickness Measurement in Hypertrophic Cardiomyopathy: Biomarker Variability and its Impact on Clinical Care. JACC Cardiovasc Imaging. 2021 11; 14(11):2123-2134. PMID: 34147459.
    Citations: 1     Fields:    Translation:Humans
  9. Marston NA, Han L, Olivotto I, Day SM, Ashley EA, Michels M, Pereira AC, Ingles J, Semsarian C, Jacoby D, Colan SD, Rossano JW, Wittekind SG, Ware JS, Saberi S, Helms AS, Ho CY. Clinical characteristics and outcomes in childhood-onset hypertrophic cardiomyopathy. Eur Heart J. 2021 05 21; 42(20):1988-1996. PMID: 33769460.
    Citations: 7     Fields:    Translation:Humans
  10. Spertus JA, Fine JT, Elliott P, Ho CY, Olivotto I, Saberi S, Li W, Dolan C, Reaney M, Sehnert AJ, Jacoby D. Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): health status analysis of a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2021 06 26; 397(10293):2467-2475. PMID: 34004177.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  11. Thompson AD, Helms AS, Kannan A, Yob J, Lakdawala NK, Wittekind SG, Pereira AC, Jacoby DL, Colan SD, Ashley EA, Saberi S, Ware JS, Ingles J, Semsarian C, Michels M, Mazzarotto F, Olivotto I, Ho CY, Day SM. Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation. Genet Med. 2021 07; 23(7):1281-1287. PMID: 33782553.
    Citations: 1     Fields:    Translation:Humans
  12. Repetti GG, Kim Y, Pereira AC, Ingles J, Russell MW, Lakdawala NK, Ho CY, Day S, Semsarian C, McDonough B, DePalma SR, Quiat D, Green EM, Seidman CE, Seidman JG. Discordant clinical features of identical hypertrophic cardiomyopathy twins. Proc Natl Acad Sci U S A. 2021 03 09; 118(10). PMID: 33658374.
    Citations: 3     Fields:    Translation:Humans
  13. Morales A, Ing A, Antolik C, Austin-Tse C, Baudhuin LM, Bronicki L, Cirino A, Hawley MH, Fietz M, Garcia J, Ho C, Ingles J, Jarinova O, Johnston T, Kelly MA, Kurtz CL, Lebo M, Macaya D, Mahanta L, Maleszewski J, Manrai AK, Murray M, Richard G, Semsarian C, Thomson KL, Winder T, Ware JS, Hershberger RE, Funke BH, Vatta M. Harmonizing the Collection of Clinical Data on Genetic Testing Requisition Forms to Enhance Variant Interpretation in Hypertrophic Cardiomyopathy (HCM): A Study from the ClinGen Cardiomyopathy Variant Curation Expert Panel. J Mol Diagn. 2021 05; 23(5):589-598. PMID: 33631351.
    Citations:    Fields:    Translation:Humans
  14. Jacoby D, Ho CY, Lester SJ, Wang A, Olivotto I. Mavacamten for hypertrophic obstructive cardiomyopathy - Authors' reply. Lancet. 2021 01 30; 397(10272):369-370. PMID: 33516332.
    Citations: 1     Fields:    Translation:Humans
  15. Harper AR, Goel A, Grace C, Thomson KL, Petersen SE, Xu X, Waring A, Ormondroyd E, Kramer CM, Ho CY, Neubauer S, Tadros R, Ware JS, Bezzina CR, Farrall M, Watkins H. Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Nat Genet. 2021 02; 53(2):135-142. PMID: 33495597.
    Citations: 20     Fields:    Translation:HumansCells
  16. Lakdawala NK, Olivotto I, Day SM, Han L, Ashley EA, Michels M, Ingles J, Semsarian C, Jacoby D, Jefferies JL, Colan SD, Pereira AC, Rossano JW, Wittekind S, Ware JS, Saberi S, Helms AS, Cirino AL, Leinwand LA, Seidman CE, Ho CY. Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy. Circ Genom Precis Med. 2021 02; 14(1):e003062. PMID: 33284039.
    Citations: 5     Fields:    Translation:HumansCells
  17. Ho CY. Guidelines on the Verge of a More Evidence-Based Era for Hypertrophic Cardiomyopathy. Circulation. 2021 01 26; 143(4):295-297. PMID: 33215933.
    Citations:    Fields:    Translation:Humans
  18. Ahluwalia M, Ho CY. Cardiovascular genetics: the role of genetic testing in diagnosis and management of patients with hypertrophic cardiomyopathy. Heart. 2021 02; 107(3):183-189. PMID: 33172912.
    Citations: 1     Fields:    Translation:Humans
  19. Zhang X, Walsh R, Whiffin N, Buchan R, Midwinter W, Wilk A, Govind R, Li N, Ahmad M, Mazzarotto F, Roberts A, Theotokis PI, Mazaika E, Allouba M, de Marvao A, Pua CJ, Day SM, Ashley E, Colan SD, Michels M, Pereira AC, Jacoby D, Ho CY, Olivotto I, Gunnarsson GT, Jefferies JL, Semsarian C, Ingles J, O'Regan DP, Aguib Y, Yacoub MH, Cook SA, Barton PJR, Bottolo L, Ware JS. Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions. Genet Med. 2021 01; 23(1):69-79. PMID: 33046849.
    Citations: 2     Fields:    Translation:Humans
  20. Canepa M, Fumagalli C, Tini G, Vincent-Tompkins J, Day SM, Ashley EA, Mazzarotto F, Ware JS, Michels M, Jacoby D, Ho CY, Olivotto I. Temporal Trend of Age at Diagnosis in Hypertrophic Cardiomyopathy: An Analysis of the International Sarcomeric Human Cardiomyopathy Registry. Circ Heart Fail. 2020 09; 13(9):e007230. PMID: 32894986.
    Citations: 8     Fields:    Translation:Humans
  21. Olivotto I, Oreziak A, Barriales-Villa R, Abraham TP, Masri A, Garcia-Pavia P, Saberi S, Lakdawala NK, Wheeler MT, Owens A, Kubanek M, Wojakowski W, Jensen MK, Gimeno-Blanes J, Afshar K, Myers J, Hegde SM, Solomon SD, Sehnert AJ, Zhang D, Li W, Bhattacharya M, Edelberg JM, Waldman CB, Lester SJ, Wang A, Ho CY, Jacoby D. Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2020 09 12; 396(10253):759-769. PMID: 32871100.
    Citations: 61     Fields:    Translation:HumansCTClinical Trials
  22. Helms AS, Thompson AD, Glazier AA, Hafeez N, Kabani S, Rodriguez J, Yob JM, Woolcock H, Mazzarotto F, Lakdawala NK, Wittekind SG, Pereira AC, Jacoby DL, Colan SD, Ashley EA, Saberi S, Ware JS, Ingles J, Semsarian C, Michels M, Olivotto I, Ho CY, Day SM. Spatial and Functional Distribution of MYBPC3 Pathogenic Variants and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy. Circ Genom Precis Med. 2020 10; 13(5):396-405. PMID: 32841044.
    Citations: 8     Fields:    Translation:HumansCells
  23. Ho CY, Olivotto I, Jacoby D, Lester SJ, Roe M, Wang A, Waldman CB, Zhang D, Sehnert AJ, Heitner SB. Study Design and Rationale of EXPLORER-HCM: Evaluation of Mavacamten in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy. Circ Heart Fail. 2020 06; 13(6):e006853. PMID: 32498620.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  24. Ho CY, Mealiffe ME, Bach RG, Bhattacharya M, Choudhury L, Edelberg JM, Hegde SM, Jacoby D, Lakdawala NK, Lester SJ, Ma Y, Marian AJ, Nagueh SF, Owens A, Rader F, Saberi S, Sehnert AJ, Sherrid MV, Solomon SD, Wang A, Wever-Pinzon O, Wong TC, Heitner SB. Evaluation of Mavacamten in Symptomatic Patients With Nonobstructive Hypertrophic Cardiomyopathy. J Am Coll Cardiol. 2020 06 02; 75(21):2649-2660. PMID: 32466879.
    Citations: 25     Fields:    Translation:HumansCTClinical Trials
  25. Miron A, Lafreniere-Roula M, Steve Fan CP, Armstrong KR, Dragulescu A, Papaz T, Manlhiot C, Kaufman B, Butts RJ, Gardin L, Stephenson EA, Howard TS, Aziz PF, Balaji S, Ladouceur VB, Benson LN, Colan SD, Godown J, Henderson HT, Ingles J, Jeewa A, Jefferies JL, Lal AK, Mathew J, Jean-St-Michel E, Michels M, Nakano SJ, Olivotto I, Parent JJ, Pereira AC, Semsarian C, Whitehill RD, Wittekind SG, Russell MW, Conway J, Richmond ME, Villa C, Weintraub RG, Rossano JW, Kantor PF, Ho CY, Mital S. A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy. Circulation. 2020 07 21; 142(3):217-229. PMID: 32418493.
    Citations: 20     Fields:    Translation:HumansPHPublic Health
  26. Nijenkamp LLAM, Bollen IAE, Niessen HWM, Dos Remedios CG, Michels M, Poggesi C, Ho CY, Kuster DWD, van der Velden J. Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy. PLoS One. 2020; 15(5):e0232427. PMID: 32369506.
    Citations: 6     Fields:    Translation:HumansCells
  27. Adalsteinsdottir B, Burke M, Maron BJ, Danielsen R, Lopez B, Diez J, Jarolim P, Seidman J, Seidman CE, Ho CY, Gunnarsson GT. Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers. Open Heart. 2020; 7(1):e001220. PMID: 32341788.
    Citations: 4     Fields:    Translation:HumansCells
  28. Marstrand P, Han L, Day SM, Olivotto I, Ashley EA, Michels M, Pereira AC, Wittekind SG, Helms A, Saberi S, Jacoby D, Ware JS, Colan SD, Semsarian C, Ingles J, Lakdawala NK, Ho CY. Hypertrophic Cardiomyopathy With Left Ventricular Systolic Dysfunction: Insights From the SHaRe Registry. Circulation. 2020 04 28; 141(17):1371-1383. PMID: 32228044.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  29. Pirruccello JP, Bick A, Chaffin M, Aragam KG, Choi SH, Lubitz SA, Ho CY, Ng K, Philippakis A, Ellinor PT, Kathiresan S, Khera AV. Titin Truncating Variants in Adults Without Known Congestive Heart Failure. J Am Coll Cardiol. 2020 03 17; 75(10):1239-1241. PMID: 32164899.
    Citations: 10     Fields:    Translation:Humans
  30. Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JF, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE. Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation. 2020 03 10; 141(10):828-842. PMID: 31983222.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  31. Fumagalli C, Maurizi N, Day SM, Ashley EA, Michels M, Colan SD, Jacoby D, Marchionni N, Vincent-Tompkins J, Ho CY, Olivotto I. Association of Obesity With Adverse Long-term Outcomes in Hypertrophic Cardiomyopathy. JAMA Cardiol. 2020 01 01; 5(1):65-72. PMID: 31693057.
    Citations: 21     Fields:    Translation:Humans
  32. Eberly LA, Day SM, Ashley EA, Jacoby DL, Jefferies JL, Colan SD, Rossano JW, Semsarian C, Pereira AC, Olivotto I, Ingles J, Seidman CE, Channaoui N, Cirino AL, Han L, Ho CY, Lakdawala NK. Association of Race With Disease Expression and Clinical Outcomes Among Patients With Hypertrophic Cardiomyopathy. JAMA Cardiol. 2020 01 01; 5(1):83-91. PMID: 31799990.
    Citations: 10     Fields:    Translation:Humans
  33. Axelsson Raja A, Shi L, Day SM, Russell M, Zahka K, Lever H, Colan SD, Margossian R, Hall EK, Becker J, Jefferies JL, Patel AR, Choudhury L, Murphy AM, Canter C, Bach R, Taylor M, Mestroni L, Wheeler MT, Benson L, Owens AT, Rossano J, Lin KY, Pahl E, Pereira AC, Bundgaard H, Lewis GD, Vargas JD, Cirino AL, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E, Ho CY. Baseline Characteristics of the VANISH Cohort. Circ Heart Fail. 2019 12; 12(12):e006231. PMID: 31813281.
    Citations: 3     Fields:    Translation:HumansCells
  34. Semsarian C, Ho CY. Screening children at risk for hypertrophic cardiomyopathy: balancing benefits and harms. Eur Heart J. 2019 12 01; 40(45):3682-3684. PMID: 31289813.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  35. Neubauer S, Kolm P, Ho CY, Kwong RY, Desai MY, Dolman SF, Appelbaum E, Desvigne-Nickens P, DiMarco JP, Friedrich MG, Geller N, Harper AR, Jarolim P, Jerosch-Herold M, Kim DY, Maron MS, Schulz-Menger J, Piechnik SK, Thomson K, Zhang C, Watkins H, Weintraub WS, Kramer CM. Distinct Subgroups in Hypertrophic Cardiomyopathy in the NHLBI HCM Registry. J Am Coll Cardiol. 2019 11 12; 74(19):2333-2345. PMID: 31699273.
    Citations: 29     Fields:    Translation:Humans
  36. Hershberger RE, Givertz MM, Ho CY, Judge DP, Kantor PF, McBride KL, Morales A, Taylor MRG, Vatta M, Ware SM. Correction: Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2019 Oct; 21(10):2406-2409. PMID: 31040388.
    Citations: 1     Fields:    
  37. Harris S, Cirino AL, Carr CW, Tafessu HM, Parmar S, Greenberg JO, Szent-Gyorgyi LE, Ghazinouri R, Glowny MG, McNeil K, Kaynor EF, Neumann C, Seidman CE, MacRae CA, Ho CY, Lakdawala NK. The uptake of family screening in hypertrophic cardiomyopathy and an online video intervention to facilitate family communication. Mol Genet Genomic Med. 2019 11; 7(11):e940. PMID: 31482667.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  38. Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Lakdawala NK, Ware JS, Helms AS, Colan SD, Seidman CE, Olivotto I. Response by Ho et al to Letter Regarding Article, "Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)". Circulation. 2019 03 19; 139(12):1559-1560. PMID: 30883221.
    Citations:    Fields:    Translation:HumansCells
  39. Walsh R, Mazzarotto F, Whiffin N, Buchan R, Midwinter W, Wilk A, Li N, Felkin L, Ingold N, Govind R, Ahmad M, Mazaika E, Allouba M, Zhang X, de Marvao A, Day SM, Ashley E, Colan SD, Michels M, Pereira AC, Jacoby D, Ho CY, Thomson KL, Watkins H, Barton PJR, Olivotto I, Cook SA, Ware JS. Quantitative approaches to variant classification increase the yield and precision of genetic testing in Mendelian diseases: the case of hypertrophic cardiomyopathy. Genome Med. 2019 01 29; 11(1):5. PMID: 30696458.
    Citations: 32     Fields:    Translation:Humans
  40. Vigneault DM, Yang E, Jensen PJ, Tee MW, Farhad H, Chu L, Noble JA, Day SM, Colan SD, Russell MW, Towbin J, Sherrid MV, Canter CE, Shi L, Ho CY, Bluemke DA. Left Ventricular Strain Is Abnormal in Preclinical and Overt Hypertrophic Cardiomyopathy: Cardiac MR Feature Tracking. Radiology. 2019 03; 290(3):640-648. PMID: 30561279.
    Citations: 20     Fields:    Translation:HumansCells
  41. Cirino AL, Seidman CE, Ho CY. Genetic Testing and Counseling for Hypertrophic Cardiomyopathy. Cardiol Clin. 2019 Feb; 37(1):35-43. PMID: 30447714.
    Citations: 5     Fields:    Translation:Humans
  42. Groarke JD, Galazka PZ, Cirino AL, Lakdawala NK, Thune JJ, Bundgaard H, Orav EJ, Levine RA, Ho CY. Intrinsic mitral valve alterations in hypertrophic cardiomyopathy sarcomere mutation carriers. Eur Heart J Cardiovasc Imaging. 2018 10 01; 19(10):1109-1116. PMID: 30052928.
    Citations: 5     Fields:    Translation:HumansCells
  43. Lee SP, Ashley EA, Homburger J, Caleshu C, Green EM, Jacoby D, Colan SD, Arteaga-Fernández E, Day SM, Girolami F, Olivotto I, Michels M, Ho CY, Perez MV. Incident Atrial Fibrillation Is Associated With MYH7 Sarcomeric Gene Variation in Hypertrophic Cardiomyopathy. Circ Heart Fail. 2018 09; 11(9):e005191. PMID: 30354366.
    Citations: 12     Fields:    Translation:HumansCells
  44. Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Cirino AL, Fox JC, Lakdawala NK, Ware JS, Caleshu CA, Helms AS, Colan SD, Girolami F, Cecchi F, Seidman CE, Sajeev G, Signorovitch J, Green EM, Olivotto I. Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe). Circulation. 2018 10 02; 138(14):1387-1398. PMID: 30297972.
    Citations: 117     Fields:    Translation:HumansCells
  45. Williams LK, Misurka J, Ho CY, Chan WX, Agmon Y, Seidman C, Rakowski H, Carasso S. Multilayer Myocardial Mechanics in Genotype-Positive Left Ventricular Hypertrophy-Negative Patients With Hypertrophic Cardiomyopathy. Am J Cardiol. 2018 11 15; 122(10):1754-1760. PMID: 30249441.
    Citations: 7     Fields:    Translation:HumansCells
  46. Axelsson Raja A, Farhad H, Valente AM, Couce JP, Jefferies JL, Bundgaard H, Zahka K, Lever H, Murphy AM, Ashley E, Day SM, Sherrid MV, Shi L, Bluemke DA, Canter CE, Colan SD, Ho CY. Prevalence and Progression of Late Gadolinium Enhancement in Children and Adolescents With Hypertrophic Cardiomyopathy. Circulation. 2018 08 21; 138(8):782-792. PMID: 29622585.
    Citations: 18     Fields:    Translation:Humans
  47. Hershberger RE, Givertz MM, Ho CY, Judge DP, Kantor PF, McBride KL, Morales A, Taylor MRG, Vatta M, Ware SM. Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2018 09; 20(9):899-909. PMID: 29904160.
    Citations: 57     Fields:    Translation:HumansPHPublic Health
  48. Nijenkamp LLAM, Bollen IAE, van Velzen HG, Regan JA, van Slegtenhorst M, Niessen HWM, Schinkel AFL, Krüger M, Poggesi C, Ho CY, Kuster DWD, Michels M, van der Velden J. Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy. Circ Heart Fail. 2018 06; 11(6):e004133. PMID: 29853478.
    Citations: 17     Fields:    Translation:HumansCells
  49. Vigneault DM, Xie W, Ho CY, Bluemke DA, Noble JA. O-Net (Omega-Net): Fully automatic, multi-view cardiac MR detection, orientation, and segmentation with deep neural networks. Med Image Anal. 2018 08; 48:95-106. PMID: 29857330.
    Citations: 23     Fields:    Translation:Humans
  50. Allen LA, Adler ED, Bayés-Genis A, Brisco-Bacik MA, Chirinos JA, Claggett B, Cook JL, Fang JC, Gustafsson F, Ho CY, Kapur NK, Klewer SE, Kociol RD, Lanfear DE, Vardeny O, Sweitzer NK. When the VEST Does Not Fit: Representations of Trial Results Deviating From Rigorous Data Interpretation. Circ Heart Fail. 2018 04; 11(4):e005116. PMID: 29666074.
    Citations:    Fields:    Translation:Humans
  51. Hershberger RE, Givertz MM, Ho CY, Judge DP, Kantor PF, McBride KL, Morales A, Taylor MRG, Vatta M, Ware SM. Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline. J Card Fail. 2018 May; 24(5):281-302. PMID: 29567486.
    Citations: 69     Fields:    Translation:Humans
  52. Ho CY, Link MS. Predicting the Future in Hypertrophic Cardiomyopathy. Circulation. 2018 03 06; 137(10):1024-1026. PMID: 29506995.
    Citations: 2     Fields:    Translation:Humans
  53. Farhad H, Seidelmann SB, Vigneault D, Abbasi SA, Yang E, Day SM, Colan SD, Russell MW, Towbin J, Sherrid MV, Canter CE, Shi L, Jerosch-Herold M, Bluemke DA, Ho C, Neilan TG. Left Atrial structure and function in hypertrophic cardiomyopathy sarcomere mutation carriers with and without left ventricular hypertrophy. J Cardiovasc Magn Reson. 2017 12 28; 19(1):107. PMID: 29284499.
    Citations: 11     Fields:    Translation:HumansCells
  54. Captur G, Arbustini E, Bonne G, Syrris P, Mills K, Wahbi K, Mohiddin SA, McKenna WJ, Pettit S, Ho CY, Muchir A, Gissen P, Elliott PM, Moon JC. Lamin and the heart. Heart. 2018 03; 104(6):468-479. PMID: 29175975.
    Citations: 47     Fields:    Translation:Humans
  55. Montag J, Syring M, Rose J, Weber AL, Ernstberger P, Mayer AK, Becker E, Keyser B, Dos Remedios C, Perrot A, van der Velden J, Francino A, Navarro-Lopez F, Ho CY, Brenner B, Kraft T. Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy. J Muscle Res Cell Motil. 2017 08; 38(3-4):291-302. PMID: 29101517.
    Citations: 13     Fields:    Translation:HumansCells
  56. Ho JE, Shi L, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy A, Taylor M, Mestroni L, Cirino AL, Sleeper LA, Jarolim P, Lopez B, Gonzalez A, Diez J, Orav EJ, Ho CY. Biomarkers of cardiovascular stress and fibrosis in preclinical hypertrophic cardiomyopathy. Open Heart. 2017; 4(2):e000615. PMID: 29177058.
    Citations: 11     Fields:    
  57. Furqan A, Arscott P, Girolami F, Cirino AL, Michels M, Day SM, Olivotto I, Ho CY, Ashley E, Green EM, Caleshu C. Care in Specialized Centers and Data Sharing Increase Agreement in Hypertrophic Cardiomyopathy Genetic Test Interpretation. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 28986452.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  58. Cirino AL, Lakdawala NK, McDonough B, Conner L, Adler D, Weinfeld M, O'Gara P, Rehm HL, Machini K, Lebo M, Blout C, Green RC, MacRae CA, Seidman CE, Ho CY. A Comparison of Whole Genome Sequencing to Multigene Panel Testing in Hypertrophic Cardiomyopathy Patients. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 29030401.
    Citations: 28     Fields:    Translation:HumansCells
  59. Cirino AL, Harris S, Lakdawala NK, Michels M, Olivotto I, Day SM, Abrams DJ, Charron P, Caleshu C, Semsarian C, Ingles J, Rakowski H, Judge DP, Ho CY. Role of Genetic Testing in Inherited Cardiovascular Disease: A Review. JAMA Cardiol. 2017 10 01; 2(10):1153-1160. PMID: 28793145.
    Citations: 24     Fields:    Translation:Humans
  60. Ho CY, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy AM, Cirino AL, Abraham TP, Taylor M, Mestroni L, Bluemke DA, Jarolim P, Shi L, Sleeper LA, Seidman CE, Orav EJ. The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study. JAMA Cardiol. 2017 04 01; 2(4):419-428. PMID: 28241245.
    Citations: 18     Fields:    Translation:HumansCells
  61. Ho CY, McMurray JJV, Cirino AL, Colan SD, Day SM, Desai AS, Lipshultz SE, MacRae CA, Shi L, Solomon SD, Orav EJ, Braunwald E. The Design of the Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Trial. Am Heart J. 2017 May; 187:145-155. PMID: 28454798.
    Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
  62. Kumar S, Baldinger SH, Gandjbakhch E, Maury P, Sellal JM, Androulakis AF, Waintraub X, Charron P, Rollin A, Richard P, Stevenson WG, Macintyre CJ, Ho CY, Thompson T, Vohra JK, Kalman JM, Zeppenfeld K, Sacher F, Tedrow UB, Lakdawala NK. Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers. J Am Coll Cardiol. 2016 11 29; 68(21):2299-2307. PMID: 27884249.
    Citations: 73     Fields:    Translation:Humans
  63. Ho CY, Cirino AL, Lakdawala NK, Groarke J, Valente AM, Semsarian C, Colan SD, Orav EJ. Evolution of hypertrophic cardiomyopathy in sarcomere mutation carriers. Heart. 2016 Nov 15; 102(22):1805-1812. PMID: 27590665.
    Citations: 11     Fields:    
  64. Hiremath P, Lawler PR, Ho JE, Correia AW, Abbasi SA, Kwong RY, Jerosch-Herold M, Ho CY, Cheng S. Ultrasonic Assessment of Myocardial Microstructure in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy. Circ Heart Fail. 2016 09; 9(9). PMID: 27623770.
    Citations: 5     Fields:    Translation:Humans
  65. Captur G, Ho CY, Schlossarek S, Kerwin J, Mirabel M, Wilson R, Rosmini S, Obianyo C, Reant P, Bassett P, Cook AC, Lindsay S, McKenna WJ, Mills K, Elliott PM, Mohun TJ, Carrier L, Moon JC. The embryological basis of subclinical hypertrophic cardiomyopathy. Sci Rep. 2016 Jun 21; 6:27714. PMID: 27323879.
    Citations: 16     Fields:    Translation:HumansAnimals
  66. Homburger JR, Green EM, Caleshu C, Sunitha MS, Taylor RE, Ruppel KM, Metpally RP, Colan SD, Michels M, Day SM, Olivotto I, Bustamante CD, Dewey FE, Ho CY, Spudich JA, Ashley EA. Multidimensional structure-function relationships in human ß-cardiac myosin from population-scale genetic variation. Proc Natl Acad Sci U S A. 2016 06 14; 113(24):6701-6. PMID: 27247418.
    Citations: 44     Fields:    Translation:Humans
  67. Ho CY. Integrating Genetics and Medicine: Disease-Modifying Treatment Strategies for Hypertrophic Cardiomyopathy. Prog Pediatr Cardiol. 2016 Mar; 40:21-23. PMID: 27182189.
    Citations: 1     
  68. Axelsson A, Iversen K, Vejlstrup N, Ho CY, Havndrup O, Kofoed KF, Norsk J, Jensen M, Bundgaard H. Functional effects of losartan in hypertrophic cardiomyopathy-a randomised clinical trial. Heart. 2016 02 15; 102(4):285-91. PMID: 26661322.
    Citations: 6     Fields:    Translation:Humans
  69. Axelsson A, Iversen K, Vejlstrup N, Langhoff L, Thomsen A, Ho CY, Havndrup O, Kofoed KF, Jensen M, Bundgaard H. Left ventricular volume predicts exercise capacity in hypertrophic cardiomyopathy. Int J Cardiol. 2016 Jan 15; 203:676-8. PMID: 26583841.
    Citations: 2     Fields:    Translation:Humans
  70. Lim L, Chan HN, Chew PH, Chua SM, Ho C, Kwek SK, Lee TS, Loh P, Lum A, Tan YH, Wan YM, Woo M, Yap HL. Ministry of Health Clinical Practice Guidelines: Anxiety Disorders. Singapore Med J. 2015 Jun; 56(6):310-5; quiz 316. PMID: 26106237.
    Citations:    Fields:    Translation:Humans
  71. Kramer CM, Appelbaum E, Desai MY, Desvigne-Nickens P, DiMarco JP, Friedrich MG, Geller N, Heckler S, Ho CY, Jerosch-Herold M, Ivey EA, Keleti J, Kim DY, Kolm P, Kwong RY, Maron MS, Schulz-Menger J, Piechnik S, Watkins H, Weintraub WS, Wu P, Neubauer S. Hypertrophic Cardiomyopathy Registry: The rationale and design of an international, observational study of hypertrophic cardiomyopathy. Am Heart J. 2015 Aug; 170(2):223-30. PMID: 26299218.
    Citations: 49     Fields:    Translation:Humans
  72. Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL. CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015 Apr; 17(4):319. PMID: 25835197.
    Citations: 7     Fields:    
  73. Ho CY, Charron P, Richard P, Girolami F, Van Spaendonck-Zwarts KY, Pinto Y. Genetic advances in sarcomeric cardiomyopathies: state of the art. Cardiovasc Res. 2015 Apr 01; 105(4):397-408. PMID: 25634555.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  74. van der Velden J, Ho CY, Tardiff JC, Olivotto I, Knollmann BC, Carrier L. Research priorities in sarcomeric cardiomyopathies. Cardiovasc Res. 2015 Apr 01; 105(4):449-56. PMID: 25631582.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  75. Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL. Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015 Nov; 17(11):880-8. PMID: 25611685.
    Citations: 142     Fields:    Translation:Humans
  76. Coppini R, Ho CY, Ashley E, Day S, Ferrantini C, Girolami F, Tomberli B, Bardi S, Torricelli F, Cecchi F, Mugelli A, Poggesi C, Tardiff J, Olivotto I. Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations. J Am Coll Cardiol. 2014 Dec 23; 64(24):2589-2600. PMID: 25524337.
    Citations: 39     Fields:    Translation:HumansCells
  77. Axelsson A, Iversen K, Vejlstrup N, Ho C, Norsk J, Langhoff L, Ahtarovski K, Corell P, Havndrup O, Jensen M, Bundgaard H. Efficacy and safety of the angiotensin II receptor blocker losartan for hypertrophic cardiomyopathy: the INHERIT randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol. 2015 Feb; 3(2):123-31. PMID: 25533774.
    Citations: 28     Fields:    Translation:Humans
  78. Ho CY, Lakdawala NK, Cirino AL, Lipshultz SE, Sparks E, Abbasi SA, Kwong RY, Antman EM, Semsarian C, González A, López B, Diez J, Orav EJ, Colan SD, Seidman CE. Diltiazem treatment for pre-clinical hypertrophic cardiomyopathy sarcomere mutation carriers: a pilot randomized trial to modify disease expression. JACC Heart Fail. 2015 Feb; 3(2):180-8. PMID: 25543971.
    Citations: 60     Fields:    Translation:HumansCells
  79. Captur G, Lopes LR, Mohun TJ, Patel V, Li C, Bassett P, Finocchiaro G, Ferreira VM, Esteban MT, Muthurangu V, Sherrid MV, Day SM, Canter CE, McKenna WJ, Seidman CE, Bluemke DA, Elliott PM, Ho CY, Moon JC. Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy. Circ Cardiovasc Imaging. 2014 Nov; 7(6):863-71. PMID: 25228707.
    Citations: 29     Fields:    Translation:HumansCells
  80. Witjas-Paalberends ER, Ferrara C, Scellini B, Piroddi N, Montag J, Tesi C, Stienen GJ, Michels M, Ho CY, Kraft T, Poggesi C, van der Velden J. Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation. J Physiol. 2014 Aug 01; 592(15):3257-72. PMID: 24928957.
    Citations: 41     Fields:    Translation:HumansCells
  81. Captur G, Mohun TJ, Finocchiaro G, Wilson R, Levine J, Conner L, Lopes L, Patel V, Sado DM, Li C, Bassett P, Herrey A, Tome Esteban M, McKenna WJ, Seidman C, Muthurangu V, Bluemke DA, Ho CY, Elliott PM, Moon JC. 126 Advanced Assessment of Cardiac Morphology and Prediction of Gene Carriage by CMR in Hypertrophic Cardiomyopathy - The HCMNET/UCL Collaboration. Heart. 2014 Jun; 100 Suppl 3:A72-3. PMID: 24922922.
  82. Witjas-Paalberends ER, Güçlü A, Germans T, Knaapen P, Harms HJ, Vermeer AM, Christiaans I, Wilde AA, Dos Remedios C, Lammertsma AA, van Rossum AC, Stienen GJ, van Slegtenhorst M, Schinkel AF, Michels M, Ho CY, Poggesi C, van der Velden J. Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations. Cardiovasc Res. 2014 Jul 15; 103(2):248-57. PMID: 24835277.
    Citations: 49     Fields:    Translation:HumansCells
  83. Vassy JL, Lautenbach DM, McLaughlin HM, Kong SW, Christensen KD, Krier J, Kohane IS, Feuerman LZ, Blumenthal-Barby J, Roberts JS, Lehmann LS, Ho CY, Ubel PA, MacRae CA, Seidman CE, Murray MF, McGuire AL, Rehm HL, Green RC. The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials. 2014 Mar 20; 15:85. PMID: 24645908.
    Citations: 77     Fields:    Translation:Humans
  84. Poggesi C, Ho CY. Muscle dysfunction in hypertrophic cardiomyopathy: what is needed to move to translation? J Muscle Res Cell Motil. 2014 Feb; 35(1):37-45. PMID: 24493262.
    Citations: 13     Fields:    Translation:HumansAnimals
  85. Shimada YJ, Passeri JJ, Baggish AL, O'Callaghan C, Lowry PA, Yannekis G, Abbara S, Ghoshhajra BB, Rothman RD, Ho CY, Januzzi JL, Seidman CE, Fifer MA. Effects of losartan on left ventricular hypertrophy and fibrosis in patients with nonobstructive hypertrophic cardiomyopathy. JACC Heart Fail. 2013 Dec; 1(6):480-7. PMID: 24621999.
    Citations: 38     Fields:    Translation:Humans
  86. Saboo SS, Steigner M, Ghosh N, Ho C, Groarke JD. Multimodality non-invasive imaging of a coronary cameral fistula. Eur Heart J Cardiovasc Imaging. 2014 Feb; 15(2):231. PMID: 24084516.
    Citations: 1     Fields:    Translation:Humans
  87. Ho CY. Erratum to: Hypertrophic Cardiomyopathy: Preclinical and Early Phenotype. J Cardiovasc Transl Res. 2013 Aug; 6(4):662. PMID: 23780787.
  88. Cirino AL, Ho CY. Genetic testing for inherited heart disease. Circulation. 2013 Jul 02; 128(1):e4-8. PMID: 23817488.
    Citations: 6     Fields:    Translation:Humans
  89. Valente AM, Lakdawala NK, Powell AJ, Evans SP, Cirino AL, Orav EJ, MacRae CA, Colan SD, Ho CY. Comparison of echocardiographic and cardiac magnetic resonance imaging in hypertrophic cardiomyopathy sarcomere mutation carriers without left ventricular hypertrophy. Circ Cardiovasc Genet. 2013 Jun; 6(3):230-7. PMID: 23690394.
    Citations: 18     Fields:    Translation:HumansCells
  90. Ho CY, Abbasi SA, Neilan TG, Shah RV, Chen Y, Heydari B, Cirino AL, Lakdawala NK, Orav EJ, González A, López B, Díez J, Jerosch-Herold M, Kwong RY. T1 measurements identify extracellular volume expansion in hypertrophic cardiomyopathy sarcomere mutation carriers with and without left ventricular hypertrophy. Circ Cardiovasc Imaging. 2013 May 01; 6(3):415-22. PMID: 23549607.
    Citations: 77     Fields:    Translation:HumansCells
  91. Sequeira V, Wijnker PJ, Nijenkamp LL, Kuster DW, Najafi A, Witjas-Paalberends ER, Regan JA, Boontje N, Ten Cate FJ, Germans T, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, Dos Remedios C, Stienen GJ, Ho CY, Michels M, van der Velden J. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations. Circ Res. 2013 May 24; 112(11):1491-505. PMID: 23508784.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  92. Dunn KE, Caleshu C, Cirino AL, Ho CY, Ashley EA. A clinical approach to inherited hypertrophy: the use of family history in diagnosis, risk assessment, and management. Circ Cardiovasc Genet. 2013 Feb; 6(1):118-31. PMID: 23424256.
    Citations: 13     Fields:    Translation:Humans
  93. Lakdawala NK, Thune JJ, Colan SD, Cirino AL, Farrohi F, Rivero J, McDonough B, Sparks E, Orav EJ, Seidman JG, Seidman CE, Ho CY. Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy. Circ Cardiovasc Genet. 2012 Oct 01; 5(5):503-10. PMID: 22949430.
    Citations: 28     Fields:    Translation:HumansCells
  94. Ashley EA, Hershberger RE, Caleshu C, Ellinor PT, Garcia JG, Herrington DM, Ho CY, Johnson JA, Kittner SJ, Macrae CA, Mudd-Martin G, Rader DJ, Roden DM, Scholes D, Sellke FW, Towbin JA, Van Eyk J, Worrall BB. Genetics and cardiovascular disease: a policy statement from the American Heart Association. Circulation. 2012 Jul 03; 126(1):142-57. PMID: 22645291.
    Citations: 27     Fields:    Translation:Humans
  95. Ho CY. Genetic considerations in hypertrophic cardiomyopathy. Prog Cardiovasc Dis. 2012 May-Jun; 54(6):456-60. PMID: 22687586.
    Citations: 6     Fields:    Translation:Humans
  96. Ho CY. Hypertrophic cardiomyopathy in 2012. Circulation. 2012 Mar 20; 125(11):1432-8. PMID: 22431884.
    Citations: 19     Fields:    Translation:Humans
  97. Noureldin RA, Liu S, Nacif MS, Judge DP, Halushka MK, Abraham TP, Ho C, Bluemke DA. The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2012 Feb 20; 14:17. PMID: 22348519.
    Citations: 52     Fields:    Translation:Humans
  98. Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE. Truncations of titin causing dilated cardiomyopathy. N Engl J Med. 2012 Feb 16; 366(7):619-28. PMID: 22335739.
    Citations: 492     Fields:    Translation:Humans
  99. Lakdawala NK, Funke BH, Baxter S, Cirino AL, Roberts AE, Judge DP, Johnson N, Mendelsohn NJ, Morel C, Care M, Chung WK, Jones C, Psychogios A, Duffy E, Rehm HL, White E, Seidman JG, Seidman CE, Ho CY. Genetic testing for dilated cardiomyopathy in clinical practice. J Card Fail. 2012 Apr; 18(4):296-303. PMID: 22464770.
    Citations: 51     Fields:    Translation:HumansCells
  100. Lakdawala NK, Thune JJ, Maron BJ, Cirino AL, Havndrup O, Bundgaard H, Christiansen M, Carlsen CM, Dorval JF, Kwong RY, Colan SD, Køber LV, Ho CY. Electrocardiographic features of sarcomere mutation carriers with and without clinically overt hypertrophic cardiomyopathy. Am J Cardiol. 2011 Dec 01; 108(11):1606-13. PMID: 21943931.
    Citations: 20     Fields:    Translation:HumansCells
  101. Ho CY. New Paradigms in Hypertrophic Cardiomyopathy: Insights from Genetics. Prog Pediatr Cardiol. 2011 May; 31(2):93-98. PMID: 21686060.
    Citations: 6     
  102. Ho CY. Genetics and clinical destiny: improving care in hypertrophic cardiomyopathy. Circulation. 2010 Dec 07; 122(23):2430-40; discussion 2440. PMID: 21135371.
    Citations: 37     Fields:    Translation:Humans
  103. Maron BJ, Roberts WC, Ho CY, Kitner C, Haas TS, Wright GB, Moazami N, Feldman DS. Profound left ventricular remodeling associated with LAMP2 cardiomyopathy. Am J Cardiol. 2010 Oct 15; 106(8):1194-6. PMID: 20920663.
    Citations: 1     Fields:    Translation:Humans
  104. Ho CY, López B, Coelho-Filho OR, Lakdawala NK, Cirino AL, Jarolim P, Kwong R, González A, Colan SD, Seidman JG, Díez J, Seidman CE. Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy. N Engl J Med. 2010 Aug 05; 363(6):552-63. PMID: 20818890.
    Citations: 212     Fields:    Translation:Humans
  105. Zimmerman RS, Cox S, Lakdawala NK, Cirino A, Mancini-DiNardo D, Clark E, Leon A, Duffy E, White E, Baxter S, Alaamery M, Farwell L, Weiss S, Seidman CE, Seidman JG, Ho CY, Rehm HL, Funke BH. A novel custom resequencing array for dilated cardiomyopathy. Genet Med. 2010 May; 12(5):268-78. PMID: 20474083.
    Citations: 31     Fields:    Translation:Humans
  106. Saltzman AJ, Mancini-DiNardo D, Li C, Chung WK, Ho CY, Hurst S, Wynn J, Care M, Hamilton RM, Seidman GW, Gorham J, McDonough B, Sparks E, Seidman JG, Seidman CE, Rehm HL. Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy. Circ Res. 2010 May 14; 106(9):1549-52. PMID: 20378854.
    Citations: 24     Fields:    Translation:Humans
  107. Girolami F, Ho CY, Semsarian C, Baldi M, Will ML, Baldini K, Torricelli F, Yeates L, Cecchi F, Ackerman MJ, Olivotto I. Clinical features and outcome of hypertrophic cardiomyopathy associated with triple sarcomere protein gene mutations. J Am Coll Cardiol. 2010 Apr 06; 55(14):1444-53. PMID: 20359594.
    Citations: 86     Fields:    Translation:HumansCells
  108. Ho CY. Hypertrophic cardiomyopathy. Heart Fail Clin. 2010 Apr; 6(2):141-59. PMID: 20347784.
    Citations: 18     Fields:    Translation:HumansCells
  109. Lakdawala NK, Dellefave L, Redwood CS, Sparks E, Cirino AL, Depalma S, Colan SD, Funke B, Zimmerman RS, Robinson P, Watkins H, Seidman CE, Seidman JG, McNally EM, Ho CY. Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy. J Am Coll Cardiol. 2010 Jan 26; 55(4):320-9. PMID: 20117437.
    Citations: 55     Fields:    Translation:HumansCells
  110. Wu JC, Ho CY, Skali H, Abichandani R, Wilcox WR, Banikazemi M, Packman S, Sims K, Solomon SD. Cardiovascular manifestations of Fabry disease: relationships between left ventricular hypertrophy, disease severity, and alpha-galactosidase A activity. Eur Heart J. 2010 May; 31(9):1088-97. PMID: 20061327.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  111. Lakdawala N, Ho CY. Hypertrophic Cardiomyopathy. Garcia MJ, Editor Non-invasive Cardiac Imaging: A Multimodality Approach. 2010; 490-507.
  112. Ho CY. Hypertrophic cardiomyopathy: preclinical and early phenotype. J Cardiovasc Transl Res. 2009 Dec; 2(4):462-70. PMID: 20560004.
    Citations: 14     Fields:    Translation:HumansAnimals
  113. Ho CY, Carlsen C, Thune JJ, Havndrup O, Bundgaard H, Farrohi F, Rivero J, Cirino AL, Andersen PS, Christiansen M, Maron BJ, Orav EJ, Køber L. Echocardiographic strain imaging to assess early and late consequences of sarcomere mutations in hypertrophic cardiomyopathy. Circ Cardiovasc Genet. 2009 Aug; 2(4):314-21. PMID: 20031602.
    Citations: 55     Fields:    Translation:HumansCells
  114. Ho CY, MacRae CA. Defining the pathogenicity of DNA sequence variation. Circ Cardiovasc Genet. 2009 Apr; 2(2):95-7. PMID: 20031572.
    Citations: 9     Fields:    Translation:HumansCells
  115. Ho CY. [Clinical spectrum of preclinical hypertrophic cardiomyopathy: characterizing carriers of sarcomere gene mutation]. Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Apr; 37(4):289-93. PMID: 19791460.
    Citations:    Fields:    Translation:HumansCells
  116. Maron BJ, Roberts WC, Arad M, Haas TS, Spirito P, Wright GB, Almquist AK, Baffa JM, Saul JP, Ho CY, Seidman J, Seidman CE. Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy. JAMA. 2009 Mar 25; 301(12):1253-9. PMID: 19318653.
    Citations: 99     Fields:    Translation:HumansCells
  117. Maron BJ, Ho CY. Hypertrophic cardiomyopathy without hypertrophy: an emerging pre-clinical subgroup composed of genetically affected family members. JACC Cardiovasc Imaging. 2009 Jan; 2(1):65-8. PMID: 19356535.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  118. Ho CY. Hypertrophic Cardiomyopathy and Other Forms of Hypertrophy. Roden D, Editor. Cardiovascular Genetics and Genomics. 2009; 96-117.
  119. Nguyen VT, Ho JE, Ho CY, Givertz MM, Stevenson LW. Handheld echocardiography offers rapid assessment of clinical volume status. Am Heart J. 2008 Sep; 156(3):537-42. PMID: 18760138.
    Citations: 9     Fields:    Translation:Humans
  120. Judge DP, Johnson NM, Cirino AL, Ho CY. Heart failure and genomics. J Am Coll Cardiol. 2007 Mar 13; 49(10):1106; author reply 1106-7. PMID: 17349893.
    Citations:    Fields:    Translation:Humans
  121. Ho CY and Seidman CE, . Inherited Cardiomyopathies. Rimoin DL, Connor JM, Pyeritz RE, and Korf BR, Editors, Principles and Practice of Medical Genetics. 2007; 2:1160-1183.
  122. Cirino AL, Ho CY. Genetic testing in cardiac disease: from bench to bedside. Nat Clin Pract Cardiovasc Med. 2006 Sep; 3(9):462-3. PMID: 16932758.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  123. Ho CY, Seidman CE. A contemporary approach to hypertrophic cardiomyopathy. Circulation. 2006 Jun 20; 113(24):e858-62. PMID: 16785342.
    Citations: 42     Fields:    Translation:HumansCells
  124. Song L, DePalma SR, Kharlap M, Zenovich AG, Cirino A, Mitchell R, McDonough B, Maron BJ, Seidman CE, Seidman JG, Ho CY. Novel locus for an inherited cardiomyopathy maps to chromosome 7. Circulation. 2006 May 09; 113(18):2186-92. PMID: 16651466.
    Citations: 7     Fields:    Translation:HumansCells
  125. Ho CY, Solomon SD. A clinician's guide to tissue Doppler imaging. Circulation. 2006 Mar 14; 113(10):e396-8. PMID: 16534017.
    Citations: 75     Fields:    Translation:Humans
  126. Ho CY. Echocardiographic Assessment of Diastolic Function. Solomon SD, editor. Essential Echocardiography. 2006; 119-131.
  127. Song, L, DePalma SR, Khrlap M, Zenovich AG, Cirino A, Mitchell R, McDonough B, Maron, BJ, Seidman CE, Seidman JG, Ho CY. A novel locus for inherited cardiomyopathy maps to chromosome 7. Circulation. 2006; 113:2186-2192.
  128. Ho CY and Seidman CE. Genetics and Heart Failure: Hypertrophic Cardiomyopathy. Baughman KL and Baumgartner WA, Editors. Treatment of Advanced Heart Disease. 2006; 589-605.
  129. Arad M, Penas-Lado M, Monserrat L, Maron BJ, Sherrid M, Ho CY, Barr S, Karim A, Olson TM, Kamisago M, Seidman JG, Seidman CE. Gene mutations in apical hypertrophic cardiomyopathy. Circulation. 2005 Nov 01; 112(18):2805-11. PMID: 16267253.
    Citations: 80     Fields:    Translation:HumansCells
  130. Paul S, Mihaljevic T, Leacche M, Landzberg M, Ho CY, Blake GJ, Byrne JG. Postinfarction ventricular septal defect with pseudoaneurysm repair after failed percutaneous closure. Ann Thorac Surg. 2005 Feb; 79(2):701-3. PMID: 15680870.
    Citations:    Fields:    Translation:Humans
  131. Arad M, Penas-Lado M, Monserrat L, Maron BJ, Sherrid M, Ho CY, Barr S, Karim A, Olson TM, Kamisago M, Seidman JG, Seidman CE. Gene mutations in apical hypertrophic cardiomyopathy. Circulation. 2005; 112:2805-2811.
  132. Ho CY and Seidman CE. Genetics of hypertrophic cardiomyopathy. Maron BJ, editor. Diagnosis and Management of Hypertrophic Cardiomyopathy, Sudden Death Prevention and Athletes. 2004; 37-66.
  133. Ho CY and Seidman CE. Inherited Cardiomyopathies. Rosenzweig TA, editor, Principles of Molecular Medicine. 2003; N/A.
  134. Khan HH, Maisel WH, Ho C, Suzuki M, Soejima K, Solomon S, Stevenson WG. Effect of radiofrequency catheter ablation of ventricular tachycardia on left ventricular function in patients with prior myocardial infarction. J Interv Card Electrophysiol. 2002 Dec; 7(3):243-7. PMID: 12510135.
    Citations: 7     Fields:    Translation:Humans
  135. Ho CY, Sweitzer NK, McDonough B, Maron BJ, Casey SA, Seidman JG, Seidman CE, Solomon SD. Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy. Circulation. 2002 Jun 25; 105(25):2992-7. PMID: 12081993.
    Citations: 123     Fields:    Translation:HumansCTClinical Trials
  136. Khan HK, Maisel WH, Ho CY, Suzuki M, Soejima K, Solomon S, Stevenson WG. . Effect of radiofrequency catheter ablation of ventricular tachycardia on left ventricular function in patients with prior myocardial infarction. Journal of Interventional Cardiac Electrophysiology. 2002; 7:243-247.
  137. Ho CY, Lever HM, DeSanctis R, Farver CF, Seidman JG, Seidman CE. Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy. Circulation. 2000 Oct 17; 102(16):1950-5. PMID: 11034944.
    Citations: 37     Fields:    Translation:Humans
  138. Ho CY, Otterud B, Legare RD, Varvil T, Saxena R, DeHart DB, Kohler SE, Aster JC, Dowton SB, Li FP, Leppert M, Gilliland DG. Linkage of a familial platelet disorder with a propensity to develop myeloid malignancies to human chromosome 21q22.1-22.2. Blood. 1996 Jun 15; 87(12):5218-24. PMID: 8652836.
    Citations: 21     Fields:    Translation:HumansCells
  139. Ho CY. A familial platelet disorder with propensity to develop myeloid leukemia is linked to chromosome 21. 1995.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.