Harvard Catalyst Profiles

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Carolyn Yung Ho, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P50HL112349 (HO, CAROLYN Y) May 15, 2012 - Jul 31, 2018
    NIH/NHLBI
    Using Genetics For Early Phenotyping & Prevention of Hypertrophic Cardiomyopathy
    Role: Principal Investigator
  2. P20HL101408 (HO, CAROLYN Y) Apr 1, 2010 - Mar 31, 2013
    NIH/NHLBI
    Using Genetics for Early Phenotyping &Prevention of Hypertrophic Cardiomyopathy
    Role: Principal Investigator
  3. K23HL078901 (HO, CAROLYN Y) Sep 26, 2005 - Jul 31, 2011
    NIH/NHLBI
    Diagnostic and Treatment Strategies for Preclinical HCM
    Role: Principal Investigator
  4. F32HL068466 (HO, CAROLYN Y) Jul 1, 2002 - Jun 30, 2004
    NIH/NHLBI
    Diastolic Function in Hypertrophic Cardiomyopathy
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hershberger RE, Givertz MM, Ho CY, Judge DP, Kantor PF, McBride KL, Morales A, Taylor MRG, Vatta M, Ware SM. Correction: Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2019 May 01. PMID: 31040388.
    Citations:    
  2. Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Lakdawala NK, Ware JS, Helms AS, Colan SD, Seidman CE, Olivotto I. Response by Ho et al to Letter Regarding Article, "Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)". Circulation. 2019 Mar 19; 139(12):1559-1560. PMID: 30883221.
    Citations:    
  3. Walsh R, Mazzarotto F, Whiffin N, Buchan R, Midwinter W, Wilk A, Li N, Felkin L, Ingold N, Govind R, Ahmad M, Mazaika E, Allouba M, Zhang X, de Marvao A, Day SM, Ashley E, Colan SD, Michels M, Pereira AC, Jacoby D, Ho CY, Thomson KL, Watkins H, Barton PJR, Olivotto I, Cook SA, Ware JS. Quantitative approaches to variant classification increase the yield and precision of genetic testing in Mendelian diseases: the case of hypertrophic cardiomyopathy. Genome Med. 2019 01 29; 11(1):5. PMID: 30696458.
    Citations:    Fields:    
  4. Vigneault DM, Yang E, Jensen PJ, Tee MW, Farhad H, Chu L, Noble JA, Day SM, Colan SD, Russell MW, Towbin J, Sherrid MV, Canter CE, Shi L, Ho CY, Bluemke DA. Left Ventricular Strain Is Abnormal in Preclinical and Overt Hypertrophic Cardiomyopathy: Cardiac MR Feature Tracking. Radiology. 2019 Mar; 290(3):640-648. PMID: 30561279.
    Citations:    Fields:    
  5. Cirino AL, Seidman CE, Ho CY. Genetic Testing and Counseling for Hypertrophic Cardiomyopathy. Cardiol Clin. 2019 Feb; 37(1):35-43. PMID: 30447714.
    Citations:    Fields:    
  6. Groarke JD, Galazka PZ, Cirino AL, Lakdawala NK, Thune JJ, Bundgaard H, Orav EJ, Levine RA, Ho CY. Intrinsic mitral valve alterations in hypertrophic cardiomyopathy sarcomere mutation carriers. Eur Heart J Cardiovasc Imaging. 2018 10 01; 19(10):1109-1116. PMID: 30052928.
    Citations:    Fields:    
  7. Lee SP, Ashley EA, Homburger J, Caleshu C, Green EM, Jacoby D, Colan SD, Arteaga-Fernández E, Day SM, Girolami F, Olivotto I, Michels M, Ho CY, Perez MV. Incident Atrial Fibrillation Is Associated With MYH7 Sarcomeric Gene Variation in Hypertrophic Cardiomyopathy. Circ Heart Fail. 2018 Sep; 11(9):e005191. PMID: 30354366.
    Citations:    Fields:    
  8. Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Cirino AL, Fox JC, Lakdawala NK, Ware JS, Caleshu CA, Helms AS, Colan SD, Girolami F, Cecchi F, Seidman CE, Sajeev G, Signorovitch J, Green EM, Olivotto I. Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe). Circulation. 2018 Oct 02; 138(14):1387-1398. PMID: 30297972.
    Citations:    Fields:    
  9. Williams LK, Misurka J, Ho CY, Chan WX, Agmon Y, Seidman C, Rakowski H, Carasso S. Multilayer Myocardial Mechanics in Genotype-Positive Left Ventricular Hypertrophy-Negative Patients With Hypertrophic Cardiomyopathy. Am J Cardiol. 2018 Nov 15; 122(10):1754-1760. PMID: 30249441.
    Citations:    Fields:    
  10. Axelsson Raja A, Farhad H, Valente AM, Couce JP, Jefferies JL, Bundgaard H, Zahka K, Lever H, Murphy AM, Ashley E, Day SM, Sherrid MV, Shi L, Bluemke DA, Canter CE, Colan SD, Ho CY. Prevalence and Progression of Late Gadolinium Enhancement in Children and Adolescents With Hypertrophic Cardiomyopathy. Circulation. 2018 Aug 21; 138(8):782-792. PMID: 29622585.
    Citations: 1     Fields:    
  11. Hershberger RE, Givertz MM, Ho CY, Judge DP, Kantor PF, McBride KL, Morales A, Taylor MRG, Vatta M, Ware SM. Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2018 09; 20(9):899-909. PMID: 29904160.
    Citations:    Fields:    Translation:HumansPHPublic Health
  12. Nijenkamp LLAM, Bollen IAE, van Velzen HG, Regan JA, van Slegtenhorst M, Niessen HWM, Schinkel AFL, Krüger M, Poggesi C, Ho CY, Kuster DWD, Michels M, van der Velden J. Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy. Circ Heart Fail. 2018 06; 11(6):e004133. PMID: 29853478.
    Citations:    Fields:    
  13. Vigneault DM, Xie W, Ho CY, Bluemke DA, Noble JA. O-Net (Omega-Net): Fully automatic, multi-view cardiac MR detection, orientation, and segmentation with deep neural networks. Med Image Anal. 2018 08; 48:95-106. PMID: 29857330.
    Citations:    Fields:    
  14. Allen LA, Adler ED, Bayés-Genis A, Brisco-Bacik MA, Chirinos JA, Claggett B, Cook JL, Fang JC, Gustafsson F, Ho CY, Kapur NK, Klewer SE, Kociol RD, Lanfear DE, Vardeny O, Sweitzer NK. When the VEST Does Not Fit: Representations of Trial Results Deviating From Rigorous Data Interpretation. Circ Heart Fail. 2018 04; 11(4):e005116. PMID: 29666074.
    Citations:    Fields:    
  15. Hershberger RE, Givertz MM, Ho CY, Judge DP, Kantor PF, McBride KL, Morales A, Taylor MRG, Vatta M, Ware SM. Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline. J Card Fail. 2018 May; 24(5):281-302. PMID: 29567486.
    Citations: 2     Fields:    
  16. Ho CY, Link MS. Predicting the Future in Hypertrophic Cardiomyopathy. Circulation. 2018 03 06; 137(10):1024-1026. PMID: 29506995.
    Citations:    Fields:    
  17. Captur G, Arbustini E, Bonne G, Syrris P, Mills K, Wahbi K, Mohiddin SA, McKenna WJ, Pettit S, Ho CY, Muchir A, Gissen P, Elliott PM, Moon JC. Lamin and the heart. Heart. 2018 03; 104(6):468-479. PMID: 29175975.
    Citations: 9     Fields:    Translation:Humans
  18. Montag J, Syring M, Rose J, Weber AL, Ernstberger P, Mayer AK, Becker E, Keyser B, Dos Remedios C, Perrot A, van der Velden J, Francino A, Navarro-Lopez F, Ho CY, Brenner B, Kraft T. Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy. J Muscle Res Cell Motil. 2017 08; 38(3-4):291-302. PMID: 29101517.
    Citations: 5     Fields:    
  19. Ho JE, Shi L, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy A, Taylor M, Mestroni L, Cirino AL, Sleeper LA, Jarolim P, Lopez B, Gonzalez A, Diez J, Orav EJ, Ho CY. Biomarkers of cardiovascular stress and fibrosis in preclinical hypertrophic cardiomyopathy. Open Heart. 2017; 4(2):e000615. PMID: 29177058.
    Citations: 2     
  20. Cirino AL, Lakdawala NK, McDonough B, Conner L, Adler D, Weinfeld M, O'Gara P, Rehm HL, Machini K, Lebo M, Blout C, Green RC, MacRae CA, Seidman CE, Ho CY. A Comparison of Whole Genome Sequencing to Multigene Panel Testing in Hypertrophic Cardiomyopathy Patients. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 29030401.
    Citations: 4     Fields:    Translation:HumansCells
  21. Cirino AL, Harris S, Lakdawala NK, Michels M, Olivotto I, Day SM, Abrams DJ, Charron P, Caleshu C, Semsarian C, Ingles J, Rakowski H, Judge DP, Ho CY. Role of Genetic Testing in Inherited Cardiovascular Disease: A Review. JAMA Cardiol. 2017 10 01; 2(10):1153-1160. PMID: 28793145.
    Citations: 5     Fields:    
  22. Furqan A, Arscott P, Girolami F, Cirino AL, Michels M, Day SM, Olivotto I, Ho CY, Ashley E, Green EM, Caleshu C. Care in Specialized Centers and Data Sharing Increase Agreement in Hypertrophic Cardiomyopathy Genetic Test Interpretation. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 28986452.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  23. Ho CY, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy AM, Cirino AL, Abraham TP, Taylor M, Mestroni L, Bluemke DA, Jarolim P, Shi L, Sleeper LA, Seidman CE, Orav EJ. The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study. JAMA Cardiol. 2017 04 01; 2(4):419-428. PMID: 28241245.
    Citations: 4     Fields:    
  24. Ho CY, McMurray JJV, Cirino AL, Colan SD, Day SM, Desai AS, Lipshultz SE, MacRae CA, Shi L, Solomon SD, Orav EJ, Braunwald E. The Design of the Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Trial. Am Heart J. 2017 May; 187:145-155. PMID: 28454798.
    Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
  25. Kumar S, Baldinger SH, Gandjbakhch E, Maury P, Sellal JM, Androulakis AF, Waintraub X, Charron P, Rollin A, Richard P, Stevenson WG, Macintyre CJ, Ho CY, Thompson T, Vohra JK, Kalman JM, Zeppenfeld K, Sacher F, Tedrow UB, Lakdawala NK. Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers. J Am Coll Cardiol. 2016 11 29; 68(21):2299-2307. PMID: 27884249.
    Citations: 6     Fields:    Translation:Humans
  26. Ho CY, Cirino AL, Lakdawala NK, Groarke J, Valente AM, Semsarian C, Colan SD, Orav EJ. Evolution of hypertrophic cardiomyopathy in sarcomere mutation carriers. Heart. 2016 Nov 15; 102(22):1805-1812. PMID: 27590665.
    Citations: 3     Fields:    
  27. Hiremath P, Lawler PR, Ho JE, Correia AW, Abbasi SA, Kwong RY, Jerosch-Herold M, Ho CY, Cheng S. Ultrasonic Assessment of Myocardial Microstructure in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy. Circ Heart Fail. 2016 09; 9(9). PMID: 27623770.
    Citations: 2     Fields:    Translation:Humans
  28. Captur G, Ho CY, Schlossarek S, Kerwin J, Mirabel M, Wilson R, Rosmini S, Obianyo C, Reant P, Bassett P, Cook AC, Lindsay S, McKenna WJ, Mills K, Elliott PM, Mohun TJ, Carrier L, Moon JC. The embryological basis of subclinical hypertrophic cardiomyopathy. Sci Rep. 2016 Jun 21; 6:27714. PMID: 27323879.
    Citations: 3     Fields:    Translation:HumansAnimals
  29. Homburger JR, Green EM, Caleshu C, Sunitha MS, Taylor RE, Ruppel KM, Metpally RP, Colan SD, Michels M, Day SM, Olivotto I, Bustamante CD, Dewey FE, Ho CY, Spudich JA, Ashley EA. Multidimensional structure-function relationships in human ß-cardiac myosin from population-scale genetic variation. Proc Natl Acad Sci U S A. 2016 06 14; 113(24):6701-6. PMID: 27247418.
    Citations: 9     Fields:    Translation:Humans
  30. Ho CY. Integrating Genetics and Medicine: Disease-Modifying Treatment Strategies for Hypertrophic Cardiomyopathy. Prog Pediatr Cardiol. 2016 Mar; 40:21-23. PMID: 27182189.
    Citations: 1     
  31. Axelsson A, Iversen K, Vejlstrup N, Ho CY, Havndrup O, Kofoed KF, Norsk J, Jensen M, Bundgaard H. Functional effects of losartan in hypertrophic cardiomyopathy-a randomised clinical trial. Heart. 2016 02 15; 102(4):285-91. PMID: 26661322.
    Citations:    Fields:    Translation:Humans
  32. Axelsson A, Iversen K, Vejlstrup N, Langhoff L, Thomsen A, Ho CY, Havndrup O, Kofoed KF, Jensen M, Bundgaard H. Left ventricular volume predicts exercise capacity in hypertrophic cardiomyopathy. Int J Cardiol. 2016 Jan 15; 203:676-8. PMID: 26583841.
    Citations:    Fields:    Translation:Humans
  33. Kramer CM, Appelbaum E, Desai MY, Desvigne-Nickens P, DiMarco JP, Friedrich MG, Geller N, Heckler S, Ho CY, Jerosch-Herold M, Ivey EA, Keleti J, Kim DY, Kolm P, Kwong RY, Maron MS, Schulz-Menger J, Piechnik S, Watkins H, Weintraub WS, Wu P, Neubauer S. Hypertrophic Cardiomyopathy Registry: The rationale and design of an international, observational study of hypertrophic cardiomyopathy. Am Heart J. 2015 Aug; 170(2):223-30. PMID: 26299218.
    Citations: 15     Fields:    Translation:Humans
  34. Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL. CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015 Apr; 17(4):319. PMID: 25835197.
    Citations: 3     Fields:    
  35. Ho CY, Charron P, Richard P, Girolami F, Van Spaendonck-Zwarts KY, Pinto Y. Genetic advances in sarcomeric cardiomyopathies: state of the art. Cardiovasc Res. 2015 Apr 01; 105(4):397-408. PMID: 25634555.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  36. van der Velden J, Ho CY, Tardiff JC, Olivotto I, Knollmann BC, Carrier L. Research priorities in sarcomeric cardiomyopathies. Cardiovasc Res. 2015 Apr 01; 105(4):449-56. PMID: 25631582.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  37. Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL. Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015 Nov; 17(11):880-8. PMID: 25611685.
    Citations: 55     Fields:    Translation:Humans
  38. Coppini R, Ho CY, Ashley E, Day S, Ferrantini C, Girolami F, Tomberli B, Bardi S, Torricelli F, Cecchi F, Mugelli A, Poggesi C, Tardiff J, Olivotto I. Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations. J Am Coll Cardiol. 2014 Dec 23; 64(24):2589-2600. PMID: 25524337.
    Citations: 9     Fields:    Translation:HumansCells
  39. Axelsson A, Iversen K, Vejlstrup N, Ho C, Norsk J, Langhoff L, Ahtarovski K, Corell P, Havndrup O, Jensen M, Bundgaard H. Efficacy and safety of the angiotensin II receptor blocker losartan for hypertrophic cardiomyopathy: the INHERIT randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol. 2015 Feb; 3(2):123-31. PMID: 25533774.
    Citations: 14     Fields:    Translation:Humans
  40. Ho CY, Lakdawala NK, Cirino AL, Lipshultz SE, Sparks E, Abbasi SA, Kwong RY, Antman EM, Semsarian C, González A, López B, Diez J, Orav EJ, Colan SD, Seidman CE. Diltiazem treatment for pre-clinical hypertrophic cardiomyopathy sarcomere mutation carriers: a pilot randomized trial to modify disease expression. JACC Heart Fail. 2015 Feb; 3(2):180-8. PMID: 25543971.
    Citations: 32     Fields:    Translation:HumansCells
  41. Captur G, Lopes LR, Mohun TJ, Patel V, Li C, Bassett P, Finocchiaro G, Ferreira VM, Esteban MT, Muthurangu V, Sherrid MV, Day SM, Canter CE, McKenna WJ, Seidman CE, Bluemke DA, Elliott PM, Ho CY, Moon JC. Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy. Circ Cardiovasc Imaging. 2014 Nov; 7(6):863-71. PMID: 25228707.
    Citations: 14     Fields:    Translation:HumansCells
  42. Witjas-Paalberends ER, Ferrara C, Scellini B, Piroddi N, Montag J, Tesi C, Stienen GJ, Michels M, Ho CY, Kraft T, Poggesi C, van der Velden J. Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation. J Physiol. 2014 Aug 01; 592(15):3257-72. PMID: 24928957.
    Citations: 21     Fields:    Translation:HumansCells
  43. Captur G, Mohun TJ, Finocchiaro G, Wilson R, Levine J, Conner L, Lopes L, Patel V, Sado DM, Li C, Bassett P, Herrey A, Tome Esteban M, McKenna WJ, Seidman C, Muthurangu V, Bluemke DA, Ho CY, Elliott PM, Moon JC. 126 Advanced Assessment of Cardiac Morphology and Prediction of Gene Carriage by CMR in Hypertrophic Cardiomyopathy - The HCMNET/UCL Collaboration. Heart. 2014 Jun; 100 Suppl 3:A72-3. PMID: 24922922.
    Citations:    
  44. Witjas-Paalberends ER, Güçlü A, Germans T, Knaapen P, Harms HJ, Vermeer AM, Christiaans I, Wilde AA, Dos Remedios C, Lammertsma AA, van Rossum AC, Stienen GJ, van Slegtenhorst M, Schinkel AF, Michels M, Ho CY, Poggesi C, van der Velden J. Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations. Cardiovasc Res. 2014 Jul 15; 103(2):248-57. PMID: 24835277.
    Citations: 21     Fields:    Translation:HumansCells
  45. Vassy JL, Lautenbach DM, McLaughlin HM, Kong SW, Christensen KD, Krier J, Kohane IS, Feuerman LZ, Blumenthal-Barby J, Roberts JS, Lehmann LS, Ho CY, Ubel PA, MacRae CA, Seidman CE, Murray MF, McGuire AL, Rehm HL, Green RC. The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials. 2014 Mar 20; 15:85. PMID: 24645908.
    Citations: 42     Fields:    Translation:Humans
  46. Poggesi C, Ho CY. Muscle dysfunction in hypertrophic cardiomyopathy: what is needed to move to translation? J Muscle Res Cell Motil. 2014 Feb; 35(1):37-45. PMID: 24493262.
    Citations: 7     Fields:    Translation:HumansAnimals
  47. Shimada YJ, Passeri JJ, Baggish AL, O'Callaghan C, Lowry PA, Yannekis G, Abbara S, Ghoshhajra BB, Rothman RD, Ho CY, Januzzi JL, Seidman CE, Fifer MA. Effects of losartan on left ventricular hypertrophy and fibrosis in patients with nonobstructive hypertrophic cardiomyopathy. JACC Heart Fail. 2013 Dec; 1(6):480-7. PMID: 24621999.
    Citations: 17     Fields:    Translation:Humans
  48. Saboo SS, Steigner M, Ghosh N, Ho C, Groarke JD. Multimodality non-invasive imaging of a coronary cameral fistula. Eur Heart J Cardiovasc Imaging. 2014 Feb; 15(2):231. PMID: 24084516.
    Citations: 1     Fields:    Translation:Humans
  49. Ho CY. Erratum to: Hypertrophic Cardiomyopathy: Preclinical and Early Phenotype. J Cardiovasc Transl Res. 2013 Aug; 6(4):662. PMID: 23780787.
    Citations:    
  50. Cirino AL, Ho CY. Genetic testing for inherited heart disease. Circulation. 2013 Jul 02; 128(1):e4-8. PMID: 23817488.
    Citations: 5     Fields:    Translation:Humans
  51. Valente AM, Lakdawala NK, Powell AJ, Evans SP, Cirino AL, Orav EJ, MacRae CA, Colan SD, Ho CY. Comparison of echocardiographic and cardiac magnetic resonance imaging in hypertrophic cardiomyopathy sarcomere mutation carriers without left ventricular hypertrophy. Circ Cardiovasc Genet. 2013 Jun; 6(3):230-7. PMID: 23690394.
    Citations: 9     Fields:    Translation:HumansCells
  52. Ho CY, Abbasi SA, Neilan TG, Shah RV, Chen Y, Heydari B, Cirino AL, Lakdawala NK, Orav EJ, González A, López B, Díez J, Jerosch-Herold M, Kwong RY. T1 measurements identify extracellular volume expansion in hypertrophic cardiomyopathy sarcomere mutation carriers with and without left ventricular hypertrophy. Circ Cardiovasc Imaging. 2013 May 01; 6(3):415-22. PMID: 23549607.
    Citations: 47     Fields:    Translation:HumansCells
  53. Sequeira V, Wijnker PJ, Nijenkamp LL, Kuster DW, Najafi A, Witjas-Paalberends ER, Regan JA, Boontje N, Ten Cate FJ, Germans T, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, Dos Remedios C, Stienen GJ, Ho CY, Michels M, van der Velden J. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations. Circ Res. 2013 May 24; 112(11):1491-505. PMID: 23508784.
    Citations: 72     Fields:    Translation:HumansAnimalsCells
  54. Dunn KE, Caleshu C, Cirino AL, Ho CY, Ashley EA. A clinical approach to inherited hypertrophy: the use of family history in diagnosis, risk assessment, and management. Circ Cardiovasc Genet. 2013 Feb; 6(1):118-31. PMID: 23424256.
    Citations: 5     Fields:    Translation:Humans
  55. Lakdawala NK, Thune JJ, Colan SD, Cirino AL, Farrohi F, Rivero J, McDonough B, Sparks E, Orav EJ, Seidman JG, Seidman CE, Ho CY. Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy. Circ Cardiovasc Genet. 2012 Oct 01; 5(5):503-10. PMID: 22949430.
    Citations: 23     Fields:    Translation:HumansCells
  56. Ashley EA, Hershberger RE, Caleshu C, Ellinor PT, Garcia JG, Herrington DM, Ho CY, Johnson JA, Kittner SJ, Macrae CA, Mudd-Martin G, Rader DJ, Roden DM, Scholes D, Sellke FW, Towbin JA, Van Eyk J, Worrall BB. Genetics and cardiovascular disease: a policy statement from the American Heart Association. Circulation. 2012 Jul 03; 126(1):142-57. PMID: 22645291.
    Citations: 21     Fields:    Translation:Humans
  57. Ho CY. Genetic considerations in hypertrophic cardiomyopathy. Prog Cardiovasc Dis. 2012 May-Jun; 54(6):456-60. PMID: 22687586.
    Citations: 4     Fields:    Translation:Humans
  58. Ho CY. Hypertrophic cardiomyopathy in 2012. Circulation. 2012 Mar 20; 125(11):1432-8. PMID: 22431884.
    Citations: 14     Fields:    Translation:Humans
  59. Noureldin RA, Liu S, Nacif MS, Judge DP, Halushka MK, Abraham TP, Ho C, Bluemke DA. The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2012 Feb 20; 14:17. PMID: 22348519.
    Citations: 31     Fields:    Translation:Humans
  60. Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE. Truncations of titin causing dilated cardiomyopathy. N Engl J Med. 2012 Feb 16; 366(7):619-28. PMID: 22335739.
    Citations: 256     Fields:    Translation:Humans
  61. Lakdawala NK, Funke BH, Baxter S, Cirino AL, Roberts AE, Judge DP, Johnson N, Mendelsohn NJ, Morel C, Care M, Chung WK, Jones C, Psychogios A, Duffy E, Rehm HL, White E, Seidman JG, Seidman CE, Ho CY. Genetic testing for dilated cardiomyopathy in clinical practice. J Card Fail. 2012 Apr; 18(4):296-303. PMID: 22464770.
    Citations: 33     Fields:    Translation:HumansCells
  62. Lakdawala NK, Thune JJ, Maron BJ, Cirino AL, Havndrup O, Bundgaard H, Christiansen M, Carlsen CM, Dorval JF, Kwong RY, Colan SD, Køber LV, Ho CY. Electrocardiographic features of sarcomere mutation carriers with and without clinically overt hypertrophic cardiomyopathy. Am J Cardiol. 2011 Dec 01; 108(11):1606-13. PMID: 21943931.
    Citations: 14     Fields:    Translation:HumansCells
  63. Ho CY. New Paradigms in Hypertrophic Cardiomyopathy: Insights from Genetics. Prog Pediatr Cardiol. 2011 May; 31(2):93-98. PMID: 21686060.
    Citations: 5     
  64. Ho CY. Genetics and clinical destiny: improving care in hypertrophic cardiomyopathy. Circulation. 2010 Dec 07; 122(23):2430-40; discussion 2440. PMID: 21135371.
    Citations: 29     Fields:    Translation:Humans
  65. Maron BJ, Roberts WC, Ho CY, Kitner C, Haas TS, Wright GB, Moazami N, Feldman DS. Profound left ventricular remodeling associated with LAMP2 cardiomyopathy. Am J Cardiol. 2010 Oct 15; 106(8):1194-6. PMID: 20920663.
    Citations: 1     Fields:    Translation:Humans
  66. Ho CY, López B, Coelho-Filho OR, Lakdawala NK, Cirino AL, Jarolim P, Kwong R, González A, Colan SD, Seidman JG, Díez J, Seidman CE. Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy. N Engl J Med. 2010 Aug 05; 363(6):552-63. PMID: 20818890.
    Citations: 123     Fields:    Translation:Humans
  67. Zimmerman RS, Cox S, Lakdawala NK, Cirino A, Mancini-DiNardo D, Clark E, Leon A, Duffy E, White E, Baxter S, Alaamery M, Farwell L, Weiss S, Seidman CE, Seidman JG, Ho CY, Rehm HL, Funke BH. A novel custom resequencing array for dilated cardiomyopathy. Genet Med. 2010 May; 12(5):268-78. PMID: 20474083.
    Citations: 23     Fields:    Translation:Humans
  68. Saltzman AJ, Mancini-DiNardo D, Li C, Chung WK, Ho CY, Hurst S, Wynn J, Care M, Hamilton RM, Seidman GW, Gorham J, McDonough B, Sparks E, Seidman JG, Seidman CE, Rehm HL. Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy. Circ Res. 2010 May 14; 106(9):1549-52. PMID: 20378854.
    Citations: 15     Fields:    Translation:Humans
  69. Girolami F, Ho CY, Semsarian C, Baldi M, Will ML, Baldini K, Torricelli F, Yeates L, Cecchi F, Ackerman MJ, Olivotto I. Clinical features and outcome of hypertrophic cardiomyopathy associated with triple sarcomere protein gene mutations. J Am Coll Cardiol. 2010 Apr 06; 55(14):1444-53. PMID: 20359594.
    Citations: 65     Fields:    Translation:HumansCells
  70. Ho CY. Hypertrophic cardiomyopathy. Heart Fail Clin. 2010 Apr; 6(2):141-59. PMID: 20347784.
    Citations: 15     Fields:    Translation:HumansCells
  71. Lakdawala NK, Dellefave L, Redwood CS, Sparks E, Cirino AL, Depalma S, Colan SD, Funke B, Zimmerman RS, Robinson P, Watkins H, Seidman CE, Seidman JG, McNally EM, Ho CY. Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy. J Am Coll Cardiol. 2010 Jan 26; 55(4):320-9. PMID: 20117437.
    Citations: 43     Fields:    Translation:HumansCells
  72. Wu JC, Ho CY, Skali H, Abichandani R, Wilcox WR, Banikazemi M, Packman S, Sims K, Solomon SD. Cardiovascular manifestations of Fabry disease: relationships between left ventricular hypertrophy, disease severity, and alpha-galactosidase A activity. Eur Heart J. 2010 May; 31(9):1088-97. PMID: 20061327.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  73. Lakdawala N, Ho CY. Hypertrophic Cardiomyopathy. Garcia MJ, Editor Non-invasive Cardiac Imaging: A Multimodality Approach. 2010; 490-507.
  74. Ho CY. Hypertrophic cardiomyopathy: preclinical and early phenotype. J Cardiovasc Transl Res. 2009 Dec; 2(4):462-70. PMID: 20560004.
    Citations: 7     Fields:    Translation:HumansAnimals
  75. Ho CY, Carlsen C, Thune JJ, Havndrup O, Bundgaard H, Farrohi F, Rivero J, Cirino AL, Andersen PS, Christiansen M, Maron BJ, Orav EJ, Køber L. Echocardiographic strain imaging to assess early and late consequences of sarcomere mutations in hypertrophic cardiomyopathy. Circ Cardiovasc Genet. 2009 Aug; 2(4):314-21. PMID: 20031602.
    Citations: 34     Fields:    Translation:HumansCells
  76. Ho CY. [Clinical spectrum of preclinical hypertrophic cardiomyopathy: characterizing carriers of sarcomere gene mutation]. Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Apr; 37(4):289-93. PMID: 19791460.
    Citations:    Fields:    Translation:HumansCells
  77. Ho CY, MacRae CA. Defining the pathogenicity of DNA sequence variation. Circ Cardiovasc Genet. 2009 Apr; 2(2):95-7. PMID: 20031572.
    Citations: 9     Fields:    Translation:HumansCells
  78. Maron BJ, Roberts WC, Arad M, Haas TS, Spirito P, Wright GB, Almquist AK, Baffa JM, Saul JP, Ho CY, Seidman J, Seidman CE. Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy. JAMA. 2009 Mar 25; 301(12):1253-9. PMID: 19318653.
    Citations: 59     Fields:    Translation:HumansCells
  79. Maron BJ, Ho CY. Hypertrophic cardiomyopathy without hypertrophy: an emerging pre-clinical subgroup composed of genetically affected family members. JACC Cardiovasc Imaging. 2009 Jan; 2(1):65-8. PMID: 19356535.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  80. Ho CY. Hypertrophic Cardiomyopathy and Other Forms of Hypertrophy. Roden D, Editor. Cardiovascular Genetics and Genomics. 2009; 96-117.
  81. Nguyen VT, Ho JE, Ho CY, Givertz MM, Stevenson LW. Handheld echocardiography offers rapid assessment of clinical volume status. Am Heart J. 2008 Sep; 156(3):537-42. PMID: 18760138.
    Citations: 8     Fields:    Translation:Humans
  82. Judge DP, Johnson NM, Cirino AL, Ho CY. Heart failure and genomics. J Am Coll Cardiol. 2007 Mar 13; 49(10):1106; author reply 1106-7. PMID: 17349893.
    Citations:    Fields:    Translation:Humans
  83. Ho CY and Seidman CE, . Inherited Cardiomyopathies. Rimoin DL, Connor JM, Pyeritz RE, and Korf BR, Editors, Principles and Practice of Medical Genetics. 2007; 2:1160-1183.
  84. Cirino AL, Ho CY. Genetic testing in cardiac disease: from bench to bedside. Nat Clin Pract Cardiovasc Med. 2006 Sep; 3(9):462-3. PMID: 16932758.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  85. Ho CY, Seidman CE. A contemporary approach to hypertrophic cardiomyopathy. Circulation. 2006 Jun 20; 113(24):e858-62. PMID: 16785342.
    Citations: 36     Fields:    Translation:HumansCells
  86. Song L, DePalma SR, Kharlap M, Zenovich AG, Cirino A, Mitchell R, McDonough B, Maron BJ, Seidman CE, Seidman JG, Ho CY. Novel locus for an inherited cardiomyopathy maps to chromosome 7. Circulation. 2006 May 09; 113(18):2186-92. PMID: 16651466.
    Citations: 7     Fields:    Translation:HumansCells
  87. Ho CY, Solomon SD. A clinician's guide to tissue Doppler imaging. Circulation. 2006 Mar 14; 113(10):e396-8. PMID: 16534017.
    Citations: 56     Fields:    Translation:Humans
  88. Ho CY. Echocardiographic Assessment of Diastolic Function. Solomon SD, editor. Essential Echocardiography. 2006; 119-131.
  89. Song, L, DePalma SR, Khrlap M, Zenovich AG, Cirino A, Mitchell R, McDonough B, Maron, BJ, Seidman CE, Seidman JG, Ho CY. A novel locus for inherited cardiomyopathy maps to chromosome 7. Circulation. 2006; 113:2186-2192.
  90. Ho CY and Seidman CE. Genetics and Heart Failure: Hypertrophic Cardiomyopathy. Baughman KL and Baumgartner WA, Editors. Treatment of Advanced Heart Disease. 2006; 589-605.
  91. Arad M, Penas-Lado M, Monserrat L, Maron BJ, Sherrid M, Ho CY, Barr S, Karim A, Olson TM, Kamisago M, Seidman JG, Seidman CE. Gene mutations in apical hypertrophic cardiomyopathy. Circulation. 2005 Nov 01; 112(18):2805-11. PMID: 16267253.
    Citations: 50     Fields:    Translation:HumansCells
  92. Paul S, Mihaljevic T, Leacche M, Landzberg M, Ho CY, Blake GJ, Byrne JG. Postinfarction ventricular septal defect with pseudoaneurysm repair after failed percutaneous closure. Ann Thorac Surg. 2005 Feb; 79(2):701-3. PMID: 15680870.
    Citations:    Fields:    Translation:Humans
  93. Arad M, Penas-Lado M, Monserrat L, Maron BJ, Sherrid M, Ho CY, Barr S, Karim A, Olson TM, Kamisago M, Seidman JG, Seidman CE. Gene mutations in apical hypertrophic cardiomyopathy. Circulation. 2005; 112:2805-2811.
  94. Ho CY and Seidman CE. Genetics of hypertrophic cardiomyopathy. Maron BJ, editor. Diagnosis and Management of Hypertrophic Cardiomyopathy, Sudden Death Prevention and Athletes. 2004; 37-66.
  95. Ho CY and Seidman CE. Inherited Cardiomyopathies. Rosenzweig TA, editor, Principles of Molecular Medicine. 2003; N/A.
  96. Khan HH, Maisel WH, Ho C, Suzuki M, Soejima K, Solomon S, Stevenson WG. Effect of radiofrequency catheter ablation of ventricular tachycardia on left ventricular function in patients with prior myocardial infarction. J Interv Card Electrophysiol. 2002 Dec; 7(3):243-7. PMID: 12510135.
    Citations: 4     Fields:    Translation:Humans
  97. Ho CY, Sweitzer NK, McDonough B, Maron BJ, Casey SA, Seidman JG, Seidman CE, Solomon SD. Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy. Circulation. 2002 Jun 25; 105(25):2992-7. PMID: 12081993.
    Citations: 97     Fields:    Translation:HumansCTClinical Trials
  98. Khan HK, Maisel WH, Ho CY, Suzuki M, Soejima K, Solomon S, Stevenson WG. . Effect of radiofrequency catheter ablation of ventricular tachycardia on left ventricular function in patients with prior myocardial infarction. Journal of Interventional Cardiac Electrophysiology. 2002; 7:243-247.
  99. Ho CY, Lever HM, DeSanctis R, Farver CF, Seidman JG, Seidman CE. Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy. Circulation. 2000 Oct 17; 102(16):1950-5. PMID: 11034944.
    Citations: 28     Fields:    Translation:Humans
  100. Ho CY, Otterud B, Legare RD, Varvil T, Saxena R, DeHart DB, Kohler SE, Aster JC, Dowton SB, Li FP, Leppert M, Gilliland DG. Linkage of a familial platelet disorder with a propensity to develop myeloid malignancies to human chromosome 21q22.1-22.2. Blood. 1996 Jun 15; 87(12):5218-24. PMID: 8652836.
    Citations: 19     Fields:    Translation:HumansCells
  101. Ho CY. A familial platelet disorder with propensity to develop myeloid leukemia is linked to chromosome 21. 1995.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.