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Elizabeth Petri Henske, M.D.

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Mentoring
Available: 05/02/22, Expires: 01/01/28

We have a fun and passionate team of physicians and scientists and love having students join us! Prior lab experience is a plus, but some projects are not wet-lab based. TSC is a multi-system disease in which benign tumors can occur in the brain, heart, skin, kidney, and lung. Available projects range from investigation of the TSC/mTOR signaling network in patient-derived cells, to genetic studies of human TSC tumors, to metabolomic profiling of TSC cells and patient plasma. These studies are likely to have relevance to the many human cancers in which the PI3K/TSC/mTOR signaling network is dysregulated.

Available: 06/27/17, Expires: 01/01/25

Identify proteins that interact with the tuberous sclerosis complex (TSC) proteins and explore their role in the pathogenesis and treatment of TSC (an inherited disease causing autism and tumors of the kidney, lung, brain, and heart) and the related disorder, pulmonary lymphangioleiomyomatosis (LAM), which affects young women.

Human genetics of mitochondrial DNA copy number variation
Soma Weiss, 02/05/18 - 12/19/18
Inside the Unconscious Child’s Brain: Systems Neuroscience Characterization of Pediatric Brain States Under General Anesthesia
Summer, 01/01/13 - 01/31/14
Identifying small molecule modulators of Ewing Sarcoma
Summer, 06/01/10 - 08/15/10

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL148156 (HENSKE, ELIZABETH P) Jul 15, 2020 - Jun 30, 2024
    NIH
    Role of the Lysosome in the Pathogenesis and Therapy of LAM
    Role: Principal Investigator
  2. R01HL146541 (HENSKE, ELIZABETH P;SHI, WEI) Apr 1, 2019 - Mar 31, 2024
    NIH
    Pathogenic Mechanisms of Pulmonary Lymphangioleiomyomatosis
    Role: Co-Principal Investigator
  3. R01CA216922 (HENSKE, ELIZABETH P ;PRIOLO, CARMEN) Jan 15, 2018 - Dec 31, 2022
    NIH
    The Metabolic Pathogenesis of Chromophobe Renal Cell Carcinoma
    Role: Principal Investigator
  4. U01HL131022 (EL-CHEMALY, SOUHEIL ;HENSKE, ELIZABETH P) Sep 21, 2016 - Feb 28, 2025
    NIH
    The Molecular and Genetic Pathogenesis of LAM
    Role: Principal Investigator
  5. R01DK102146 (HENSKE, ELIZABETH P) Sep 10, 2015 - Jun 30, 2021
    NIH
    Induction of Oncogenic mircoRNA by rapamycin: Role in TSC Therapy
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.