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Elizabeth Petri Henske, M.D.

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Available: 05/02/22, Expires: 01/01/28

We have a fun and passionate team of physicians and scientists and love having students join us! Prior lab experience is a plus, but some projects are not wet-lab based. TSC is a multi-system disease in which benign tumors can occur in the brain, heart, skin, kidney, and lung. Available projects range from investigation of the TSC/mTOR signaling network in patient-derived cells, to genetic studies of human TSC tumors, to metabolomic profiling of TSC cells and patient plasma. These studies are likely to have relevance to the many human cancers in which the PI3K/TSC/mTOR signaling network is dysregulated.

Available: 06/27/17, Expires: 01/01/25

Identify proteins that interact with the tuberous sclerosis complex (TSC) proteins and explore their role in the pathogenesis and treatment of TSC (an inherited disease causing autism and tumors of the kidney, lung, brain, and heart) and the related disorder, pulmonary lymphangioleiomyomatosis (LAM), which affects young women.

Human genetics of mitochondrial DNA copy number variation
Soma Weiss, 02/05/18 - 12/19/18
Inside the Unconscious Child’s Brain: Systems Neuroscience Characterization of Pediatric Brain States Under General Anesthesia
Summer, 01/01/13 - 01/31/14
Identifying small molecule modulators of Ewing Sarcoma
Summer, 06/01/10 - 08/15/10

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK133243 (HENSKE, ELIZABETH P) Apr 5, 2023 - Mar 31, 2028
    Mechanisms of immunosuppression in the development and progression of renal disease in Tuberous Sclerosis Complex
    Role: Principal Investigator
  2. R01DK133354 (HENSKE, ELIZABETH P) Sep 1, 2022 - Apr 30, 2026
    Role of TFEB and TFE3 in Tuberous Sclerosis Complex (TSC) Kidney Disease
    Role: Principal Investigator
  3. R01HL148156 (HENSKE, ELIZABETH P) Jul 15, 2020 - Jun 30, 2025
    Role of the Lysosome in the Pathogenesis and Therapy of LAM
    Role: Principal Investigator
  4. R01HL146541 (HENSKE, ELIZABETH P;SHI, WEI) Apr 1, 2019 - Mar 31, 2024
    Pathogenic Mechanisms of Pulmonary Lymphangioleiomyomatosis
    Role: Co-Principal Investigator
  5. R01CA216922 (HENSKE, ELIZABETH P ;PRIOLO, CARMEN) Jan 15, 2018 - Dec 31, 2022
    The Metabolic Pathogenesis of Chromophobe Renal Cell Carcinoma
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.