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Clark, Jeffrey
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Jeffrey William Clark, M.D.
Title
Associate Professor of Medicine
Institution
Massachusetts General Hospital
Department
Medicine
Address
Massachusetts General Hospital
Hem/Onc, Cox 640
100 Blossom Street
Boston MA 02114
Phone
617/726-8743
Fax
617/724-3166
vCard
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selected publications
|
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Dias-Santagata D
,
Heist RS
, Bard AZ, da Silva AFL,
Dagogo-Jack I
,
Nardi V
,
Ritterhouse LL
,
Spring LM
, Jessop N, Farahani AA,
Mino-Kenudson M
, Allen J,
Goyal L
,
Parikh A
, Misdraji J,
Shankar G
,
Jordan JT
, Martinez-Lage M,
Frosch M
,
Graubert T
,
Fathi AT
,
Hobbs GS
,
Hasserjian RP
,
Raje N
,
Abramson J
, Schwartz JH, Sullivan RJ, Miller D,
Hoang MP
,
Isakoff S
,
Ly A
,
Bouberhan S
,
Watkins J
,
Oliva E
,
Wirth L
,
Sadow PM
,
Faquin W
,
Cote GM
,
Hung YP
,
Gao X
, Wu CL, Garg S,
Rivera M
, Le LP, John Iafrate A,
Juric D
,
Hochberg EP
,
Clark J
,
Bardia A
,
Lennerz JK
. Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network. Oncologist. 2022 11 03; 27(11):930-939.
PMID:
35852437
; PMCID:
PMC9632318
.
Citations:
Fields:
Neo
Neoplasms
Perez K
, Kulke MH, Horick NK, Regan E, Graham C, Scheutz S, Stonely D,
Enzinger PC
, Fuchs CS, Allen JN,
Enzinger AC
,
Clark JW
, Chan JA. A Phase II Study of Ziv-Aflibercept in Patients With Advanced Extrapancreatic Neuroendocrine Tumors. Pancreas. 2022 08 01; 51(7):763-768.
PMID:
36395401
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
CT
Clinical Trials
Rajurkar M,
Parikh AR
, Solovyov A, You E, Kulkarni AS, Chu C, Xu KH, Jaicks C,
Taylor MS
, Wu C, Alexander KA, Good CR, Szabolcs A, Gerstberger S, Tran AV, Xu N,
Ebright RY
, Van Seventer EE, Vo KD, Tai EC, Lu C, Joseph-Chazan J, Raabe MJ, Nieman LT, Desai N, Arora KS, Ligorio M, Thapar V, Cohen L, Garden PM,
Senussi Y
, Zheng H, Allen JN,
Blaszkowsky LS
,
Clark JW
,
Goyal L
,
Wo JY
,
Ryan DP
,
Corcoran RB
,
Deshpande V
,
Rivera MN
,
Aryee MJ
,
Hong TS
, Berger SL,
Walt DR
,
Burns KH
,
Park PJ
, Greenbaum BD, Ting DT. Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer. Cancer Discov. 2022 06 02; 12(6):1462-1481.
PMID:
35320348
; PMCID:
PMC9167735
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Zafar A, Drobni ZD, Lei M,
Gongora CA
, Quinaglia T, Lou UY, Mosarla R,
Murphy SP
,
Jones-O'Connor M
, Mahmood A, Hartmann S, Gilman HK,
Weekes CD
,
Nipp R
,
Clark JR
,
Clark JW
,
Blaszkowsky LS
, Tavares E,
Neilan TG
. The efficacy and safety of cardio-protective therapy in patients with 5-FU (Fluorouracil)-associated coronary vasospasm. PLoS One. 2022; 17(4):e0265767.
PMID:
35390017
; PMCID:
PMC8989300
.
Citations:
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Furtado FS, Wu MZ,
Esfahani SA
, Ferrone CR,
Blaszkowsky LS
,
Clark JW
,
Ryan DP
,
Goyal L
,
Franses JW
,
Wo JY
,
Hong TS
,
Qadan M
,
Tanabe KK
,
Weekes CD
,
Cusack JC
, Crafa F,
Mahmood U
,
Anderson MA
,
Mojtahed A
,
Hahn PF
,
Caravan P
,
Kilcoyne A
,
Vangel M
, Striar RR,
Rosen BR
,
Catalano OA
. Positron Emission Tomography/Magnetic Resonance Imaging Versus the Standard of Care Imaging in the Diagnosis of Peritoneal Carcinomatosis. Ann Surg. 2022 Feb 17.
PMID:
35185121
.
Citations:
1
Fields:
Gen
General Surgery
Hank T, Sandini M, Ferrone CR,
Ryan DP
,
Mino-Kenudson M
,
Qadan M
,
Wo JY
, Klaiber U,
Weekes CD
, Weniger M, Hinz U,
Harrison JM
, Heckler M,
Warshaw AL
,
Hong TS
, Hackert T,
Clark JW
, Büchler MW,
Lillemoe KD
, Strobel O, Castillo CF. A Combination of Biochemical and Pathological Parameters Improves Prediction of Postresection Survival After Preoperative Chemotherapy in Pancreatic Cancer: The PANAMA-score. Ann Surg. 2022 02 01; 275(2):391-397.
PMID:
32649455
.
Citations:
1
Fields:
Gen
General Surgery
Translation:
Humans
Parikh AR
, Szabolcs A, Allen JN,
Clark JW
,
Wo JY
, Raabe M, Thel H, Hoyos D,
Mehta A
, Arshad S, Lieb DJ, Drapek LC,
Blaszkowsky LS
, Giantonio BJ,
Weekes CD
, Zhu AX,
Goyal L
,
Nipp RD
, Dubois JS, Van Seventer EE, Foreman BE, Matlack LE, Ly L, Meurer JA,
Hacohen N
,
Ryan DP
,
Yeap BY
,
Corcoran RB
, Greenbaum BD, Ting DT,
Hong TS
. Radiation therapy enhances immunotherapy response in microsatellite stable colorectal and pancreatic adenocarcinoma in a phase II trial. Nat Cancer. 2021 11; 2(11):1124-1135.
PMID:
35122060
; PMCID:
PMC8809884
.
Citations:
9
Translation:
Humans
Cells
CT
Clinical Trials
Ho WW, Gomes-Santos IL, Aoki S, Datta M, Kawaguchi K, Talele NP, Roberge S, Ren J, Liu H, Chen IX, Andersson P, Chatterjee S, Kumar AS, Amoozgar Z, Zhang Q,
Huang P
, Ng MR, Chauhan VP,
Xu L
,
Duda DG
,
Clark JW
,
Pittet MJ
,
Fukumura D
,
Jain RK
. Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy. Proc Natl Acad Sci U S A. 2021 11 09; 118(45).
PMID:
34725151
.
Citations:
1
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Noda Y, Pisuchpen N,
Mercaldo ND
, Sekigami Y,
Michelakos T
,
Parakh A
,
Wo JY
,
Qadan M
, Ferrone C,
Lillemoe KD
,
Ryan DP
,
Clark JW
,
Fernandez-Del Castillo C
,
Hong TS
, Kambadakone AR. Arterial involvement and resectability scoring system to predict R0 resection in patients with pancreatic ductal adenocarcinoma treated with neoadjuvant chemoradiation therapy. Eur Radiol. 2022 Apr; 32(4):2470-2480.
PMID:
34665317
.
Citations:
Fields:
Rad
Radiology
Translation:
Humans
Kim DW, Lee G,
Hong TS
, Li G, Horick NK, Roeland E,
Keane FK
, Eyler C, Drapek LC,
Ryan DP
, Allen JN,
Berger D
,
Parikh AR
,
Mullen JT
,
Klempner S
,
Clark JW
,
Wo JY
. ASO Visual Abstract: Neoadjuvant versus Postoperative Chemoradiotherapy Is Associated with Improved Survival in Patients with Resectable Gastric and Gastroesophageal Cancer. Ann Surg Oncol. 2021 Dec; 28(Suppl 3):690-691.
PMID:
34490528
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Kim DW, Lee G,
Hong TS
, Li G, Horick NK, Roeland E,
Keane FK
, Eyler C, Drapek LC,
Ryan DP
, Allen JN,
Berger D
,
Parikh AR
,
Mullen JT
,
Klempner SJ
,
Clark JW
,
Wo JY
. Neoadjuvant versus Postoperative Chemoradiotherapy is Associated with Improved Survival for Patients with Resectable Gastric and Gastroesophageal Cancer. Ann Surg Oncol. 2022 Jan; 29(1):242-252.
PMID:
34480285
.
Citations:
1
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
de Klerk LK, Patel AK, Derks S, Pectasides E, Augustin J, Uduman M, Raman N, Akarca FG,
McCleary NJ
,
Cleary JM
,
Rubinson DA
,
Clark JW
, Fitzpatrick B, Brais LK, Cavanaugh ME, Rode AJ, Jean MG,
Lizotte PH
, Nazzaro MJ, Severgnini M, Zheng H, Fuchs CS,
Enzinger PC
, Bass AJ. Phase II study of pembrolizumab in refractory esophageal cancer with correlates of response and survival. J Immunother Cancer. 2021 09; 9(9).
PMID:
34593617
; PMCID:
PMC8487210
.
Citations:
1
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Wo JY
,
Clark JW
, Eyler CE,
Mino-Kenudson M
,
Klempner SJ
, Allen JN,
Keane FK
,
Parikh AR
, Roeland E, Drapek LC,
Ryan DP
,
Corcoran RB
, Van Seventer E, Fetter IJ, Shahzade HA,
Khandekar MJ
,
Lanuti M
, Morse CR,
Heist RS
, Ulysse CA, Christopher B, Baglini C,
Yeap BY
,
Mullen JT
,
Hong TS
. Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas. Clin Cancer Res. 2021 12 01; 27(23):6343-6353.
PMID:
34330715
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Furtado FS, Suarez-Weiss KE,
Vangel M
,
Clark JW
,
Cusack JC
,
Hong T
,
Blaszkowsky L
,
Wo J
, Striar R, Umutlu L, Daldrup-Link HE, Groshar D, Rocco R,
Bordeianou L
,
Anderson MA
,
Mojtahed A
,
Qadan M
, Ferrone C,
Catalano OA
. Clinical impact of PET/MRI in oligometastatic colorectal cancer. Br J Cancer. 2021 09; 125(7):975-982.
PMID:
34282295
; PMCID:
PMC8476553
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Kanter K, Fish M, Mauri G, Horick NK, Allen JN,
Blaszkowsky LS
,
Clark JW
,
Ryan DP
,
Nipp RD
, Giantonio BJ,
Goyal L
, Dubois J, Murphy JE,
Franses J
,
Klempner SJ
, Roeland EJ,
Weekes CD
,
Wo JY
,
Hong TS
, Van Seventer EE,
Corcoran RB
,
Parikh AR
. Care Patterns and Overall Survival in Patients With Early-Onset Metastatic Colorectal Cancer. JCO Oncol Pract. 2021 12; 17(12):e1846-e1855.
PMID:
34043449
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Sridharan V,
Mino-Kenudson M
,
Cleary JM
,
Rahma OE
,
Perez K
,
Clark JW
,
Clancy TE
,
Rubinson DA
,
Goyal L
, Bazerbachi F, Visrodia KH,
Qadan M
,
Parikh A
, Ferrone CR,
Casey BW
,
Fernandez-Del Castillo C
,
Ryan DP
,
Lillemoe KD
,
Warshaw AL
, Krishnan K,
Hernandez-Barco YG
. Pancreatic acinar cell carcinoma: A multi-center series on clinical characteristics and treatment outcomes. Pancreatology. 2021 May 15.
PMID:
34023183
.
Citations:
2
Fields:
End
Endocrinology
Gas
Gastroenterology
Parikh AR
, Van Seventer EE, Siravegna G, Hartwig AV, Jaimovich A, He Y, Kanter K, Fish MG, Fosbenner KD, Miao B, Phillips S, Carmichael JH, Sharma N, Jarnagin J, Baiev I, Shah YS, Fetter IJ, Shahzade HA, Allen JN,
Blaszkowsky LS
,
Clark JW
, Dubois JS,
Franses JW
, Giantonio BJ,
Goyal L
,
Klempner SJ
,
Nipp RD
, Roeland EJ,
Ryan DP
,
Weekes CD
,
Wo JY
,
Hong TS
,
Bordeianou L
, Ferrone CR,
Qadan M
,
Kunitake H
,
Berger D
,
Ricciardi R
,
Cusack JC
, Raymond VM, Talasaz A,
Boland GM
,
Corcoran RB
. Minimal Residual Disease Detection using a Plasma-only Circulating Tumor DNA Assay in Patients with Colorectal Cancer. Clin Cancer Res. 2021 10 15; 27(20):5586-5594.
PMID:
33926918
; PMCID:
PMC8530842
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Zafar A, Drobni ZD, Mosarla R, Alvi RM, Lei M, Lou UY,
Raghu VK
,
Murphy SP
,
Jones-O'Connor M
, Hartmann S, Gilman HK,
Weekes CD
,
Clark JR
,
Clark J
,
Blaszkowsky L
, Tavares E,
Neilan TG
. The Incidence, Risk Factors, and Outcomes With 5-Fluorouracil-Associated Coronary Vasospasm. JACC CardioOncol. 2021 Mar; 3(1):101-109.
PMID:
33817666
; PMCID:
PMC8018593
.
Citations:
9
Camidge DR, Otterson GA,
Clark JW
, Ignatius Ou SH, Weiss J, Ades S, Shapiro GI, Socinski MA, Murphy DA, Conte U, Tang Y, Wang SC, Wilner KD, Villaruz LC. Crizotinib in Patients With MET-Amplified NSCLC. J Thorac Oncol. 2021 06; 16(6):1017-1029.
PMID:
33676017
.
Citations:
11
Fields:
Neo
Neoplasms
Pul
Pulmonary Medicine
Translation:
Humans
Michelakos T
, Cai L, Villani V, Sabbatino F, Kontos F, Fernández-Del Castillo C, Yamada T, Neyaz A,
Taylor MS
,
Deshpande V
, Kurokawa T, Ting DT,
Qadan M
,
Weekes CD
, Allen JN,
Clark JW
,
Hong TS
,
Ryan DP
,
Wo JY
,
Warshaw AL
,
Lillemoe KD
, Ferrone S, Ferrone CR. Tumor Microenvironment Immune Response in Pancreatic Ductal Adenocarcinoma Patients Treated With Neoadjuvant Therapy. J Natl Cancer Inst. 2021 02 01; 113(2):182-191.
PMID:
32497200
; PMCID:
PMC7850539
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Michelakos T
, Sekigami Y, Kontos F, Fernández-Del Castillo C,
Qadan M
,
Deshpande V
, Ting DT,
Clark JW
,
Weekes CD
,
Parikh A
,
Ryan DP
,
Wo JY
,
Hong TS
, Allen JN,
Catalano O
,
Warshaw AL
,
Lillemoe KD
, Ferrone CR. Conditional Survival in Resected Pancreatic Ductal Adenocarcinoma Patients Treated with Total Neoadjuvant Therapy. J Gastrointest Surg. 2021 11; 25(11):2859-2870.
PMID:
33501584
.
Citations:
Fields:
Gas
Gastroenterology
Gen
General Surgery
Translation:
Humans
McDuff SGR, Hardiman KM, Ulintz PJ,
Parikh AR
, Zheng H, Kim DW,
Lennerz JK
, Hazar-Rethinam M, Van Seventer EE, Fetter IJ, Nadres B, Eyler CE,
Ryan DP
,
Weekes CD
,
Clark JW
,
Cusack JC
,
Goyal L
, Zhu AX,
Wo JY
,
Blaszkowsky LS
, Allen J,
Corcoran RB
,
Hong TS
. Circulating Tumor DNA Predicts Pathologic and Clinical Outcomes Following Neoadjuvant Chemoradiation and Surgery for Patients With Locally Advanced Rectal Cancer. JCO Precis Oncol. 2021; 5.
PMID:
34250394
; PMCID:
PMC8232395
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Furtado FS, Ferrone CR,
Lee SI
,
Vangel M
,
Rosman DA
,
Weekes C
,
Qadan M
,
Fernandez-Del Castillo C
,
Ryan DP
,
Blaszkowsky LS
,
Hong TS
,
Clark JW
, Striar R, Groshar D, Cañamaque LG, Umutlu L,
Catalano OA
. Impact of PET/MRI in the Treatment of Pancreatic Adenocarcinoma: a Retrospective Cohort Study. Mol Imaging Biol. 2021 06; 23(3):456-466.
PMID:
33415677
.
Citations:
2
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Translation:
Humans
Singh H
,
Li YY
, Spurr LF,
Shinagare AB
, Abhyankar R, Reilly E, Brais LK, Nag A, Ducar MD, Thorner AR,
Shapiro GI
, Keller RB, Siletti C,
Clark JW
, Farago AF,
Lin JJ
,
Demetri GD
, Gujrathi R, Kulke MH,
MacConaill LE
,
Ligon AH
,
Sicinska E
,
Meyerson ML
,
Meyerhardt JA
,
Cherniack AD
,
Wolpin BM
,
Ng K
,
Giannakis M
, Hornick JL,
Cleary JM
. Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions. Clin Cancer Res. 2021 03 15; 27(6):1695-1705.
PMID:
33414136
; PMCID:
PMC9063924
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Li SS
,
Klempner SJ
,
Costantino CL
,
Parikh A
,
Clark JW
,
Wo JY
,
Hong TS
,
Mullen JT
. Impact of Treatment Sequencing on Survival for Patients with Locally Advanced Gastric Cancer. Ann Surg Oncol. 2021 May; 28(5):2856-2865.
PMID:
33393043
.
Citations:
1
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
van Seventer EE, Fish MG, Fosbenner K, Kanter K,
Mojtahed A
, Allen JN,
Blaszkowsky L
,
Clark JW
, Dubois J,
Franses JW
, Giantonio BJ,
Goyal L
,
Klempner SJ
, Roeland EJ,
Ryan DP
,
Weekes CD
, Mulvey T,
El-Jawahri A
, Horick N,
Corcoran RB
,
Parikh AR
,
Nipp RD
. Associations of baseline patient-reported outcomes with treatment outcomes in advanced gastrointestinal cancer. Cancer. 2021 02 15; 127(4):619-627.
PMID:
33170962
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Chawla A,
Qadan M
, Castillo CF,
Wo JY
, Allen JN,
Clark JW
, Murphy JE,
Catalano OA
,
Ryan DP
, Ting DT,
Deshpande V
,
Weekes CD
,
Parikh A
,
Lillemoe KD
,
Hong TS
, Ferrone CR. Prospective Phase II Trials Validate the Effect of Neoadjuvant Chemotherapy on Pattern of Recurrence in Pancreatic Adenocarcinoma. Ann Surg. 2022 11 01; 276(5):e502-e509.
PMID:
33086310
.
Citations:
Fields:
Gen
General Surgery
Catalano OA
,
Lee SI
, Parente C,
Cauley C
, Furtado FS, Striar R, Soricelli A, Salvatore M, Li Y, Umutlu L, Cañamaque LG, Groshar D,
Mahmood U
,
Blaszkowsky LS
,
Ryan DP
,
Clark JW
,
Wo J
,
Hong TS
,
Kunitake H
,
Bordeianou L
,
Berger D
,
Ricciardi R
,
Rosen B
. Improving staging of rectal cancer in the pelvis: the role of PET/MRI. Eur J Nucl Med Mol Imaging. 2021 04; 48(4):1235-1245.
PMID:
33034673
.
Citations:
11
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Lee G, Kim DW, Muralidhar V, Mitra D, Horick NK, Eyler CE,
Hong TS
, Drapek LC, Allen JN,
Blaszkowsky LS
, Giantonio B,
Parikh AR
,
Ryan DP
,
Clark JW
,
Wo JY
. Chemoradiation-Related Lymphopenia and Its Association with Survival in Patients with Squamous Cell Carcinoma of the Anal Canal. Oncologist. 2020 12; 25(12):1015-1022.
PMID:
32827337
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Chaudhary SP, Kwak EL,
Hwang KL
,
Lennerz JK
,
Corcoran RB
,
Heist RS
,
Russo AL
,
Parikh A
, Borger DR,
Blaszkowsky LS
, Faris JE, Murphy JE, Azzoli CG, Roeland EJ,
Goyal L
, Allen J,
Mullen JT
,
Ryan DP
,
Iafrate AJ
,
Klempner SJ
,
Clark JW
,
Hong TS
. Revisiting MET: Clinical Characteristics and Treatment Outcomes of Patients with Locally Advanced or Metastatic, MET-Amplified Esophagogastric Cancers. Oncologist. 2020 11; 25(11):e1691-e1700.
PMID:
32820577
; PMCID:
PMC7648344
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Dee EC, Freret ME, Horick N, Raldow AC,
Goyal L
, Zhu AX,
Parikh AR
,
Ryan DP
,
Clark JW
, Allen JN, Ferrone CR,
Fernandez-Del Castillo C
,
Tanabe KK
, Drapek LC,
Hong TS
,
Qadan M
,
Wo JY
. Patterns of Failure and the Need for Biliary Intervention in Resected Biliary Tract Cancers After Chemoradiation. Ann Surg Oncol. 2020 Dec; 27(13):5161-5172.
PMID:
32740733
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Begg SKS, Birnbaum DJ,
Clark JW
,
Mino-Kenudson M
, Wellner UF, Schilling O,
Lillemoe KD
,
Warshaw AL
, Castillo CF,
Liss AS
. FOLFIRINOX Versus Gemcitabine-based Therapy for Pancreatic Ductal Adenocarcinoma: Lessons from Patient-derived Cell Lines. Anticancer Res. 2020 Jul; 40(7):3659-3667.
PMID:
32620605
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Rodrigues C, Hank T,
Qadan M
, Ciprani D,
Mino-Kenudson M
,
Weekes CD
,
Ryan DP
,
Clark JW
, Allen JN,
Hong TS
,
Wo JY
, Ferrone CR,
Warshaw AL
,
Lillemoe KD
,
Fernandez-Del Castillo C
. Impact of adjuvant therapy in patients with invasive intraductal papillary mucinous neoplasms of the pancreas. Pancreatology. 2020 Jun; 20(4):722-728.
PMID:
32222340
.
Citations:
5
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Li SS
, Udelsman BV,
Parikh A
,
Klempner SJ
,
Clark JW
, Roeland EJ,
Wo JY
,
Hong TS
,
Mullen JT
. Impact of Postoperative Complication and Completion of Multimodality Therapy on Survival in Patients Undergoing Gastrectomy for Advanced Gastric Cancer. J Am Coll Surg. 2020 06; 230(6):912-924.
PMID:
32035978
.
Citations:
11
Fields:
Gen
General Surgery
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Parikh AR
,
Mojtahed A
,
Schneider JL
, Kanter K, Van Seventer EE, Fetter IJ,
Thabet A
, Fish MG, Teshome B, Fosbenner K, Nadres B, Shahzade HA, Allen JN,
Blaszkowsky LS
,
Ryan DP
, Giantonio B,
Goyal L
,
Nipp RD
, Roeland E,
Weekes CD
,
Wo JY
, Zhu AX,
Dias-Santagata D
,
Iafrate AJ
,
Lennerz JK
,
Hong TS
, Siravegna G, Horick N,
Clark JW
,
Corcoran RB
. Serial ctDNA Monitoring to Predict Response to Systemic Therapy in Metastatic Gastrointestinal Cancers. Clin Cancer Res. 2020 04 15; 26(8):1877-1885.
PMID:
31941831
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Drilon A,
Clark JW
, Weiss J, Ou SI, Camidge DR, Solomon BJ, Otterson GA, Villaruz LC, Riely GJ,
Heist RS
,
Awad MM
, Shapiro GI, Satouchi M, Hida T, Hayashi H, Murphy DA, Wang SC, Li S, Usari T, Wilner KD, Paik PK. Antitumor activity of crizotinib in lung cancers harboring a MET exon 14 alteration. Nat Med. 2020 01; 26(1):47-51.
PMID:
31932802
; PMCID:
PMC8500676
.
Citations:
80
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Goyal L
, Chaudhary SP, Kwak EL,
Abrams TA
, Carpenter AN,
Wolpin BM
, Wadlow RC, Allen JN,
Heist R
,
McCleary NJ
,
Chan JA
,
Goessling W
, Schrag D,
Ng K
,
Enzinger PC
,
Ryan DP
,
Clark JW
. A phase 2 clinical trial of the heat shock protein 90 (HSP 90) inhibitor ganetespib in patients with refractory advanced esophagogastric cancer. Invest New Drugs. 2020 10; 38(5):1533-1539.
PMID:
31898183
.
Citations:
6
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Cavallaro P,
Bordeianou L
, Stafford C,
Clark J
,
Berger D
,
Cusack J
,
Kunitake H
, Francone T,
Ricciardi R
. Impact of Single-organ Metastasis to the Liver or Lung and Genetic Mutation Status on Prognosis in Stage IV Colorectal Cancer. Clin Colorectal Cancer. 2020 03; 19(1):e8-e17.
PMID:
31899147
.
Citations:
7
Fields:
Gas
Gastroenterology
Neo
Neoplasms
Translation:
Humans
Parikh AR
, Leshchiner I, Elagina L,
Goyal L
, Levovitz C, Siravegna G, Livitz D, Rhrissorrakrai K, Martin EE, Van Seventer EE, Hanna M, Slowik K, Utro F, Pinto CJ, Wong A, Danysh BP, de la Cruz FF, Fetter IJ, Nadres B, Shahzade HA, Allen JN,
Blaszkowsky LS
,
Clark JW
, Giantonio B, Murphy JE,
Nipp RD
, Roeland E,
Ryan DP
,
Weekes CD
, Kwak EL, Faris JE,
Wo JY
, Aguet F, Dey-Guha I, Hazar-Rethinam M,
Dias-Santagata D
, Ting DT, Zhu AX,
Hong TS
,
Golub TR
,
Iafrate AJ
, Adalsteinsson VA, Bardelli A, Parida L,
Juric D
,
Getz G
,
Corcoran RB
. Author Correction: Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. Nat Med. 2019 Dec; 25(12):1949.
PMID:
31745334
.
Citations:
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Clark JW
, Camidge DR, Kwak EL, Maki RG,
Shapiro GI
, Chen I, Tan W, Randolph S, Christensen JG, Ozeck M, Tang Y, Wilner KD, Salgia R. Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer. Future Oncol. 2020 Jan; 16(1):4289-4301.
PMID:
31778074
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Harrison JM
,
Wo JY
, Ferrone CR, Horick NK,
Keane FK
,
Qadan M
,
Lillemoe KD
,
Hong TS
,
Clark JW
,
Blaszkowsky LS
, Allen JN, Castillo CF. Intraoperative Radiation Therapy (IORT) for Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (BR/LA PDAC) in the Era of Modern Neoadjuvant Treatment: Short-Term and Long-Term Outcomes. Ann Surg Oncol. 2020 May; 27(5):1400-1406.
PMID:
31758284
.
Citations:
4
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Parikh AR
, Leshchiner I, Elagina L,
Goyal L
, Levovitz C, Siravegna G, Livitz D, Rhrissorrakrai K, Martin EE, Van Seventer EE, Hanna M, Slowik K, Utro F, Pinto CJ, Wong A, Danysh BP, de la Cruz FF, Fetter IJ, Nadres B, Shahzade HA, Allen JN,
Blaszkowsky LS
,
Clark JW
, Giantonio B, Murphy JE,
Nipp RD
, Roeland E,
Ryan DP
,
Weekes CD
, Kwak EL, Faris JE,
Wo JY
, Aguet F, Dey-Guha I, Hazar-Rethinam M,
Dias-Santagata D
, Ting DT, Zhu AX,
Hong TS
,
Golub TR
,
Iafrate AJ
, Adalsteinsson VA, Bardelli A, Parida L,
Juric D
,
Getz G
,
Corcoran RB
. Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. Nat Med. 2019 09; 25(9):1415-1421.
PMID:
31501609
; PMCID:
PMC6741444
.
Citations:
119
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Amorim BJ,
Hong TS
,
Blaszkowsky LS
, Ferrone CR,
Berger DL
,
Bordeianou LG
,
Ricciardi R
,
Clark JW
,
Ryan DP
,
Wo JY
,
Qadan M
,
Vangel M
, Umutlu L, Groshar D, Cañamaques LG,
Gervais DA
,
Mahmood U
,
Rosen BR
,
Catalano OA
. Clinical impact of PET/MR in treated colorectal cancer patients. Eur J Nucl Med Mol Imaging. 2019 Oct; 46(11):2260-2269.
PMID:
31359108
.
Citations:
10
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Murphy JE,
Wo JY
,
Ryan DP
,
Clark JW
, Jiang W,
Yeap BY
, Drapek LC, Ly L, Baglini CV,
Blaszkowsky LS
, Ferrone CR,
Parikh AR
,
Weekes CD
,
Nipp RD
, Kwak EL, Allen JN,
Corcoran RB
, Ting DT, Faris JE, Zhu AX,
Goyal L
,
Berger DL
,
Qadan M
,
Lillemoe KD
, Talele N,
Jain RK
,
DeLaney TF
,
Duda DG
,
Boucher Y
, Fernández-Del Castillo C,
Hong TS
. Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial. JAMA Oncol. 2019 Jul 01; 5(7):1020-1027.
PMID:
31145418
; PMCID:
PMC6547247
.
Citations:
138
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Wo JY
, Plastaras JP, Metz JM, Jiang W,
Yeap BY
, Drapek LC, Adams J, Baglini C,
Ryan DP
, Murphy JE,
Parikh AR
, Allen JN,
Clark JW
,
Blaszkowsky LS
,
DeLaney TF
, Ben-Josef E,
Hong TS
. Pencil Beam Scanning Proton Beam Chemoradiation Therapy With 5-Fluorouracil and Mitomycin-C for Definitive Treatment of Carcinoma of the Anal Canal: A Multi-institutional Pilot Feasibility Study. Int J Radiat Oncol Biol Phys. 2019 09 01; 105(1):90-95.
PMID:
31128146
.
Citations:
8
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Awad MM
, Leonardi GC, Kravets S,
Dahlberg SE
, Drilon A, Noonan SA, Camidge DR, Ou SI,
Costa DB
, Gadgeel SM, Steuer CE, Forde PM, Zhu VW, Fukuda Y,
Clark JW
, Jänne PA, Mok T,
Sholl LM
,
Heist RS
. Impact of MET inhibitors on survival among patients with non-small cell lung cancer harboring MET exon 14 mutations: a retrospective analysis. Lung Cancer. 2019 07; 133:96-102.
PMID:
31200835
.
Citations:
32
Fields:
Neo
Neoplasms
Translation:
Humans
Parikh AR
, He Y, Hong TS,
Corcoran RB
,
Clark JW
,
Ryan DP
,
Zou L
, Ting DT, Catenacci DV, Chao J, Fakih M,
Klempner SJ
, Ross JS, Frampton GM, Miller VA, Ali SM, Schrock AB. Analysis of DNA Damage Response Gene Alterations and Tumor Mutational Burden Across 17,486 Tubular Gastrointestinal Carcinomas: Implications for Therapy. Oncologist. 2019 10; 24(10):1340-1347.
PMID:
31040255
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Michelakos T
, Pergolini I, Castillo CF, Honselmann KC, Cai L,
Deshpande V
,
Wo JY
,
Ryan DP
, Allen JN,
Blaszkowsky LS
,
Clark JW
, Murphy JE,
Nipp RD
,
Parikh A
,
Qadan M
,
Warshaw AL
,
Hong TS
,
Lillemoe KD
, Ferrone CR. Predictors of Resectability and Survival in Patients With Borderline and Locally Advanced Pancreatic Cancer who Underwent Neoadjuvant Treatment With FOLFIRINOX. Ann Surg. 2019 04; 269(4):733-740.
PMID:
29227344
.
Citations:
70
Fields:
Gen
General Surgery
Translation:
Humans
Cleary JM
, Horick NK,
McCleary NJ
,
Abrams TA
,
Yurgelun MB
, Azzoli CG,
Rubinson DA
, Brooks GA,
Chan JA
,
Blaszkowsky LS
,
Clark JW
,
Goyal L
,
Meyerhardt JA
,
Ng K
, Schrag D, Savarese DMF, Graham C, Fitzpatrick B, Gibb KA,
Boucher Y
,
Duda DG
,
Jain RK
, Fuchs CS,
Enzinger PC
. FOLFOX plus ziv-aflibercept or placebo in first-line metastatic esophagogastric adenocarcinoma: A double-blind, randomized, multicenter phase 2 trial. Cancer. 2019 07 01; 125(13):2213-2221.
PMID:
30913304
; PMCID:
PMC6763367
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Mitra D, Horick NK,
Brackett DG
,
Mouw KW
,
Hornick JL
, Ferrone S,
Hong TS
,
Mamon H
,
Clark JW
,
Parikh AR
, Allen JN,
Ryan DP
, Ting DT,
Deshpande V
,
Wo JY
. High IDO1 Expression Is Associated with Poor Outcome in Patients with Anal Cancer Treated with Definitive Chemoradiotherapy. Oncologist. 2019 06; 24(6):e275-e283.
PMID:
30755500
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Sanford NN,
Pursley J
, Noe B,
Yeap BY
,
Goyal L
,
Clark JW
, Allen JN,
Blaszkowsky LS
,
Ryan DP
, Ferrone CR,
Tanabe KK
,
Qadan M
, Crane CH, Koay EJ, Eyler C,
DeLaney TF
, Zhu AX,
Wo JY
,
Grassberger C
,
Hong TS
. Protons versus Photons for Unresectable Hepatocellular Carcinoma: Liver Decompensation and Overall Survival. Int J Radiat Oncol Biol Phys. 2019 09 01; 105(1):64-72.
PMID:
30684667
.
Citations:
38
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Mitra D,
Clark JW
,
Shih HA
,
Oh KS
, Brastianos PK,
Wo JY
,
Strickland MR
,
Curry WT
,
Parikh AR
,
Corcoran RB
,
Ryan DP
,
Iafrate AJ
, Borger DR,
Lennerz JK
,
Hong TS
. Enrichment of HER2 Amplification in Brain Metastases from Primary Gastrointestinal Malignancies. Oncologist. 2019 02; 24(2):193-201.
PMID:
30373904
; PMCID:
PMC6369954
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Chu JN, Choi J, Ostvar S,
Torchia JA
,
Reynolds KL
, Tramontano A,
Gainor JF
,
Chung DC
,
Clark JW
, Hur C. Cost-effectiveness of immune checkpoint inhibitors for microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer. Cancer. 2019 01 15; 125(2):278-289.
PMID:
30343509
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hong TS
,
Grassberger C
,
Yeap BY
, Jiang W,
Wo JY
,
Goyal L
,
Clark JW
, Crane CH, Koay EJ, Dima S, Eyler CE, Popescu I,
DeLaney TF
, Zhu AX,
Duda DG
. Pretreatment plasma HGF as potential biomarker for susceptibility to radiation-induced liver dysfunction after radiotherapy. NPJ Precis Oncol. 2018; 2:22.
PMID:
30374460
; PMCID:
PMC6194077
.
Citations:
10
Murphy JE, Shampain K, Riley LE,
Clark JW
, Basnet KM. Case 32-2018: A 36-Year-Old Pregnant Woman with Newly Diagnosed Adenocarcinoma. N Engl J Med. 2018 Oct 18; 379(16):1562-1570.
PMID:
30332577
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Mehtsun WT,
Chipidza FE
, Fernández-Del Castillo C, Hemingway K,
Fong ZV
, Chang DC, Pandharipande P,
Clark JW
, Allen J,
Hong TS
,
Wo JY
,
Warshaw AL
,
Lillemoe KD
, Ferrone CR. Are Staging Computed Tomography (CT) Scans of the Chest Necessary in Pancreatic Adenocarcinoma? Ann Surg Oncol. 2018 Dec; 25(13):3936-3942.
PMID:
30276641
.
Citations:
3
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Goyal L
, Zheng H,
Abrams TA
, Miksad R,
Bullock AJ
, Allen JN,
Yurgelun MB
,
Clark JW
, Kambadakone A, Muzikansky A, Knowles M, Galway A, Afflitto AJ, Dinicola CF, Regan E, Hato T, Mamessier E, Shigeta K,
Jain RK
,
Duda DG
, Zhu AX. A Phase II and Biomarker Study of Sorafenib Combined with Modified FOLFOX in Patients with Advanced Hepatocellular Carcinoma. Clin Cancer Res. 2019 01 01; 25(1):80-89.
PMID:
30190369
; PMCID:
PMC6320284
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Wo JY
,
Niemierko A
,
Ryan DP
,
Blaszkowsky LS
,
Clark JW
, Kwak EL,
Lillemoe KD
, Drapek LN, Zhu AX, Allen JN, Faris JE, Murphy JE,
Nipp R
,
Fernandez-Del Castillo C
, Ferrone CR,
Hong TS
. Tolerability and Long-term Outcomes of Dose-Painted Neoadjuvant Chemoradiation to Regions of Vessel Involvement in Borderline or Locally Advanced Pancreatic Cancer. Am J Clin Oncol. 2018 07; 41(7):656-661.
PMID:
28134673
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Murphy JE,
Wo JY
,
Ryan DP
, Jiang W,
Yeap BY
, Drapek LC,
Blaszkowsky LS
, Kwak EL, Allen JN,
Clark JW
, Faris JE, Zhu AX,
Goyal L
,
Lillemoe KD
,
DeLaney TF
, Fernández-Del Castillo C, Ferrone CR,
Hong TS
. Total Neoadjuvant Therapy With FOLFIRINOX Followed by Individualized Chemoradiotherapy for Borderline Resectable Pancreatic Adenocarcinoma: A Phase 2 Clinical Trial. JAMA Oncol. 2018 07 01; 4(7):963-969.
PMID:
29800971
.
Citations:
127
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Clark JW
,
Longo DL
. Recent progress in systemic treatment for lung cancer. Curr Opin Pulm Med. 2018 07; 24(4):355-366.
PMID:
29697418
.
Citations:
3
Fields:
Pul
Pulmonary Medicine
Translation:
Humans
Keane FK
,
Wo JY
, Ferrone CR,
Clark JW
,
Blaszkowsky LS
, Allen JN, Kwak EL,
Ryan DP
,
Lillemoe KD
,
Fernandez-Del Castillo C
,
Hong TS
. Intraoperative Radiotherapy in the Era of Intensive Neoadjuvant Chemotherapy and Chemoradiotherapy for Pancreatic Adenocarcinoma. Am J Clin Oncol. 2018 06; 41(6):607-612.
PMID:
27740973
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Kamran SC
,
Clark JW
, Zheng H, Borger DR,
Blaszkowsky LS
, Allen JN, Kwak EL,
Wo JY
,
Parikh AR
,
Nipp RD
, Murphy JE,
Goyal L
, Zhu AX,
Iafrate AJ
,
Corcoran RB
,
Ryan DP
,
Hong TS
. Primary tumor sidedness is an independent prognostic marker for survival in metastatic colorectal cancer: Results from a large retrospective cohort with mutational analysis. Cancer Med. 2018 Jul; 7(7):2934-2942.
PMID:
29771009
; PMCID:
PMC6051212
.
Citations:
12
Fields:
Neo
Neoplasms
McDuff SGR, Remillard KA, Zheng H, Raldow AC,
Wo JY
, Eyler CE, Drapek LC,
Goyal L
,
Blaszkowsky LS
,
Clark JW
, Allen JN,
Parikh AR
,
Ryan DP
, Ferrone CR,
Tanabe KK
,
Wolfgang JA
, Zhu AX,
Hong TS
. Liver reirradiation for patients with hepatocellular carcinoma and liver metastasis. Pract Radiat Oncol. 2018 Nov - Dec; 8(6):414-421.
PMID:
29937235
.
Citations:
6
Fields:
Neo
Neoplasms
Rad
Radiotherapy
Translation:
Humans
Grassberger C
,
Hong TS
, Hato T,
Yeap BY
,
Wo JY
, Tracy M,
Bortfeld T
,
Wolfgang JA
, Eyler CE,
Goyal L
,
Clark JW
, Crane CH, Koay EJ, Cobbold M,
DeLaney TF
,
Jain RK
, Zhu AX,
Duda DG
. Differential Association Between Circulating Lymphocyte Populations With Outcome After Radiation Therapy in Subtypes of Liver Cancer. Int J Radiat Oncol Biol Phys. 2018 08 01; 101(5):1222-1225.
PMID:
29859792
; PMCID:
PMC6050125
.
Citations:
13
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Cells
CT
Clinical Trials
Weekes CD
,
Clark JW
, Zhu AX. Tivantinib for advanced hepatocellular carcinoma: is MET still a viable target? Lancet Oncol. 2018 05; 19(5):591-592.
PMID:
29625880
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Hazar-Rethinam M, Kleyman M, Han GC,
Liu D
, Ahronian LG, Shahzade HA, Chen L,
Parikh AR
, Allen JN,
Clark JW
, Kwak EL, Faris JE, Murphy JE,
Hong TS
, Van Seventer EE, Nadres B, Hong CB, Gurski JM, Jessop NA,
Dias-Santagata D
,
Iafrate AJ
,
Van Allen EM
,
Corcoran RB
. Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAFV600E Colorectal Cancer. Cancer Discov. 2018 04; 8(4):417-427.
PMID:
29431697
; PMCID:
PMC5882515
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK,
Clark JW
, Willett CG,
Yun SH
,
Luster AD
,
Padera TP
,
Jain RK
,
Fukumura D
. Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer. Proc Natl Acad Sci U S A. 2017 09 26; 114(39):10455-10460.
PMID:
28900008
.
Citations:
44
Fields:
Sci
Science
Translation:
Animals
Cells
Miller CL
,
Taylor MS
,
Qadan M
,
Deshpande V
, Worthington S, Smalley R, Collura C,
Ryan DP
, Allen JN,
Blaszkowsky LS
,
Clark JW
, Murphy JE,
Parikh AR
,
Berger D
,
Tanabe KK
,
Lillemoe KD
, Ferrone CR. Prognostic Significance of Surgical Margin Size After Neoadjuvant FOLFOX and/or FOLFIRI for Colorectal Liver Metastases. J Gastrointest Surg. 2017 Nov; 21(11):1831-1840.
PMID:
28884391
.
Citations:
8
Fields:
Gas
Gastroenterology
Gen
General Surgery
Translation:
Humans
Hong TS
,
Wo JY
, Borger DR,
Yeap BY
, McDonnell EI,
Willers H
,
Blaszkowsky LS
, Kwak EL, Allen JN,
Clark JW
,
Tanguturi S
,
Goyal L
, Murphy JE,
Wolfgang JA
, Drapek LC,
Arellano RS
,
Mamon HJ
,
Mullen JT
,
Tanabe KK
, Ferrone CR,
Ryan DP
,
Iafrate AJ
,
DeLaney TF
, Zhu AX. Phase II Study of Proton-Based Stereotactic Body Radiation Therapy for Liver Metastases: Importance of Tumor Genotype. J Natl Cancer Inst. 2017 09 01; 109(9).
PMID:
28954285
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E,
Clark JW
, Willett CG,
Luster AD
,
Yun SH
,
Langer R
, Anderson DG,
Padera TP
,
Jain RK
,
Fukumura D
. Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. J Clin Invest. 2017 Aug 01; 127(8):3039-3051.
PMID:
28691930
; PMCID:
PMC5531423
.
Citations:
65
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Kishan AU, Voog JC, Wiseman J, Cook RR, Ancukiewicz M, Lee P,
Ryan DP
,
Clark JW
,
Berger DL
,
Cusack JC
,
Wo JY
,
Hong TS
. Standard fractionation external beam radiotherapy with and without intraoperative radiotherapy for locally recurrent rectal cancer: the role of local therapy in patients with a high competing risk of death from distant disease. Br J Radiol. 2017 Aug; 90(1076):20170134.
PMID:
28613934
; PMCID:
PMC5603953
.
Citations:
2
Fields:
Rad
Radiology
Translation:
Humans
Liu H,
Naxerova K
, Pinter M, Incio J,
Lee H
, Shigeta K, Ho WW, Crain JA, Jacobson A,
Michelakos T
, Dias-Santos D, Zanconato A,
Hong TS
,
Clark JW
, Murphy JE,
Ryan DP
,
Deshpande V
,
Lillemoe KD
,
Fernandez-Del Castillo C
, Downes M, Evans RM, Michaelson J, Ferrone CR,
Boucher Y
,
Jain RK
. Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2017 Oct 01; 23(19):5959-5969.
PMID:
28600474
; PMCID:
PMC5856249
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Parikh A
,
Goyal L
, Hazar-Rethinam M, Siravegna G,
Blaszkowsky L
, Russo M, Van Seventer E, Nadres B, Shahzade H,
Clark J
, Allen J, John IA,
Ryan DP
, Murphy J, Bardelli A, Zhu A,
Hong T
,
Corcoran R
. Systematic liquid biopsy identifies novel and heterogeneous mechanisms of acquired resistance in gastrointestinal (GI) cancer patients. Ann Oncol. 2017 Jun; 28 Suppl 3:iii137.
PMID:
32135760
.
Citations:
Reyes S, Horick N,
Clark J
, Murphy J,
Blaszkowsky L
, Allen J,
Ryan DP
,
Hong T
, Wo J,
Nipp R
,
Parikh A
, Faris J, Kwak E, Galway A, Knowles M, Oklu R, John IA,
Lennerz J
,
Finkelstein D
, Borger D, Zhu A,
Goyal L
. Frequency and impact of tumor genotyping in clinical practice of patients with advanced biliary tract cancers (ABTCs). Ann Oncol. 2017 Jun; 28 Suppl 3:iii145-iii146.
PMID:
32135779
.
Citations:
Rose B, Mitra D,
Hong TS
, Jee KW,
Niemierko A
, Drapek LN,
Blaszkowsky LS
, Allen JN, Murphy JE,
Clark JW
,
Ryan DP
,
Wo JY
. Irradiation of anatomically defined pelvic subsites and acute hematologic toxicity in anal cancer patients undergoing chemoradiation. Pract Radiat Oncol. 2017 Sep - Oct; 7(5):e291-e297.
PMID:
28462895
.
Citations:
5
Fields:
Neo
Neoplasms
Rad
Radiotherapy
Translation:
Humans
PH
Public Health
Mitra D,
Hong TS
, Horick N, Rose B, Drapek LN,
Blaszkowsky LS
, Allen JN, Kwak EL, Murphy JE,
Clark JW
,
Ryan DP
,
Cusack JC
,
Bordeianou LG
,
Berger DL
,
Wo JY
. Long-term outcomes and toxicities of a large cohort of anal cancer patients treated with dose-painted IMRT per RTOG 0529. Adv Radiat Oncol. 2017 Apr-Jun; 2(2):110-117.
PMID:
28740921
; PMCID:
PMC5514246
.
Citations:
18
Nipp RD
, Zanconato A, Zheng H, Ferrone CR,
Lillemoe KD
,
Wo JY
,
Hong TS
,
Clark JW
,
Ryan DP
, Fernández-Del Castillo C. Predictors of Early Mortality After Surgical Resection of Pancreatic Adenocarcinoma in the Era of Neoadjuvant Treatment. Pancreas. 2017 02; 46(2):183-189.
PMID:
27846142
.
Citations:
7
Fields:
Gas
Gastroenterology
Translation:
Humans
Clark JW
,
Chabner BA
. Limits to Precision Cancer Medicine. N Engl J Med. 2017 01 05; 376(1):96.
PMID:
28052223
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
Rahbari NN, Kedrin D, Incio J, Liu H, Ho WW, Nia HT, Edrich CM, Jung K, Daubriac J, Chen I, Heishi T, Martin JD, Huang Y, Maimon N, Reissfelder C, Weitz J,
Boucher Y
,
Clark JW
, Grodzinsky AJ,
Duda DG
,
Jain RK
,
Fukumura D
. Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases. Sci Transl Med. 2016 10 12; 8(360):360ra135.
PMID:
27733559
; PMCID:
PMC5457741
.
Citations:
92
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Heist RS
,
Sequist LV
, Borger D,
Gainor JF
,
Arellano RS
,
Le LP
,
Dias-Santagata D
,
Clark JW
, Engelman JA,
Shaw AT
,
Iafrate AJ
. Acquired Resistance to Crizotinib in NSCLC with METÂ Exon 14 Skipping. J Thorac Oncol. 2016 08; 11(8):1242-1245.
PMID:
27343442
.
Citations:
55
Fields:
Neo
Neoplasms
Pul
Pulmonary Medicine
Translation:
Humans
Setia N,
Agoston AT
, Han HS,
Mullen JT
,
Duda DG
,
Clark JW
,
Deshpande V
,
Mino-Kenudson M
,
Srivastava A
,
Lennerz JK
,
Hong TS
, Kwak EL, Lauwers GY. A protein and mRNA expression-based classification of gastric cancer. Mod Pathol. 2016 07; 29(7):772-84.
PMID:
27032689
.
Citations:
49
Fields:
Pat
Pathology
Translation:
Humans
Cells
Indolfi L, Ligorio M, Ting DT, Xega K, Tzafriri AR, Bersani F, Aceto N, Thapar V, Fuchs BC,
Deshpande V
, Baker AB, Ferrone CR,
Haber DA
,
Langer R
,
Clark JW
,
Edelman ER
. A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma. Biomaterials. 2016 07; 93:71-82.
PMID:
27082874
.
Citations:
11
Fields:
Bio
Biomedical Engineering
Translation:
Humans
Animals
Cells
Fuentes E, Ahmad R,
Hong TS
,
Clark JW
, Kwak EL, Rattner DW,
Mullen JT
. The impact of neoadjuvant therapy for gastroesophageal adenocarcinoma on postoperative morbidity and mortality. J Surg Oncol. 2016 Apr; 113(5):560-4.
PMID:
26792144
.
Citations:
2
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Hong TS
,
Wo JY
,
Yeap BY
, Ben-Josef E, McDonnell EI,
Blaszkowsky LS
, Kwak EL, Allen JN,
Clark JW
,
Goyal L
, Murphy JE, Javle MM,
Wolfgang JA
, Drapek LC,
Arellano RS
,
Mamon HJ
,
Mullen JT
, Yoon SS,
Tanabe KK
, Ferrone CR,
Ryan DP
,
DeLaney TF
, Crane CH, Zhu AX. Multi-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma. J Clin Oncol. 2016 Feb 10; 34(5):460-8.
PMID:
26668346
; PMCID:
PMC4872014
.
Citations:
149
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Kurzrock R, Colevas AD, Olszanski A, Akerley W, Arteaga CL, Carson WE,
Clark JW
, DiPersio JF, Ettinger DS, Morgan RJ, Schwartzberg LS, Venook AP, Gocke CD, Tait J, Stewart FM. NCCN Oncology Research Program's Investigator Steering Committee and NCCN Best Practices Committee Molecular Profiling Surveys. J Natl Compr Canc Netw. 2015 Nov; 13(11):1337-46.
PMID:
26553764
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Kwak EL, Ahronian LG, Siravegna G, Mussolin B, Borger DR, Godfrey JT, Jessop NA,
Clark JW
,
Blaszkowsky LS
,
Ryan DP
,
Lennerz JK
,
Iafrate AJ
, Bardelli A,
Hong TS
,
Corcoran RB
. Molecular Heterogeneity and Receptor Coamplification Drive Resistance to Targeted Therapy in MET-Amplified Esophagogastric Cancer. Cancer Discov. 2015 12; 5(12):1271-81.
PMID:
26432108
.
Citations:
71
Fields:
Neo
Neoplasms
Translation:
Humans
Sarantopoulos J,
Shapiro GI
, Cohen RB,
Clark JW
, Kauh JS, Weiss GJ,
Cleary JM
, Mahalingam D, Pickard MD, Faessel HM, Berger AJ,
Burke K
, Mulligan G, Dezube BJ, Harvey RD. Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors. Clin Cancer Res. 2016 Feb 15; 22(4):847-57.
PMID:
26423795
.
Citations:
68
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Setia N,
Clark JW
,
Duda DG
,
Hong TS
, Kwak EL,
Mullen JT
, Lauwers GY. Familial Gastric Cancers. Oncologist. 2015 Dec; 20(12):1365-77.
PMID:
26424758
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Fuentes E, Ahmad R,
Hong TS
,
Clark JW
, Kwak EL, Rattner DW,
Mullen JT
. Adjuvant Therapy Completion Rates in Patients with Gastric Cancer Undergoing Perioperative Chemotherapy Versus a Surgery-First Approach. J Gastrointest Surg. 2016 Jan; 20(1):172-9; discussion 179.
PMID:
26394879
.
Citations:
7
Fields:
Gas
Gastroenterology
Gen
General Surgery
Translation:
Humans
Goyal L
, Govindan A, Sheth RA,
Nardi V
,
Blaszkowsky LS
, Faris JE,
Clark JW
,
Ryan DP
, Kwak EL, Allen JN, Murphy JE, Saha SK,
Hong TS
,
Wo JY
, Ferrone CR,
Tanabe KK
, Chong DQ,
Deshpande V
, Borger DR,
Iafrate AJ
, Bardeesy N, Zheng H, Zhu AX. Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma. Oncologist. 2015 Sep; 20(9):1019-27.
PMID:
26245674
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Humans
Ferrone CR, Marchegiani G,
Hong TS
,
Ryan DP
,
Deshpande V
, McDonnell EI, Sabbatino F, Santos DD, Allen JN,
Blaszkowsky LS
,
Clark JW
, Faris JE,
Goyal L
, Kwak EL, Murphy JE, Ting DT,
Wo JY
, Zhu AX,
Warshaw AL
,
Lillemoe KD
, Fernández-del Castillo C. Radiological and surgical implications of neoadjuvant treatment with FOLFIRINOX for locally advanced and borderline resectable pancreatic cancer. Ann Surg. 2015 Jan; 261(1):12-7.
PMID:
25599322
; PMCID:
PMC4349683
.
Citations:
212
Fields:
Gen
General Surgery
Translation:
Humans
Shaw AT
, Ou SH, Bang YJ, Camidge DR, Solomon BJ, Salgia R, Riely GJ, Varella-Garcia M,
Shapiro GI
,
Costa DB
, Doebele RC,
Le LP
, Zheng Z, Tan W, Stephenson P, Shreeve SM, Tye LM, Christensen JG, Wilner KD,
Clark JW
,
Iafrate AJ
. Crizotinib in ROS1-rearranged non-small-cell lung cancer. N Engl J Med. 2014 Nov 20; 371(21):1963-71.
PMID:
25264305
; PMCID:
PMC4264527
.
Citations:
641
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Dahlberg SE
,
Shapiro GI
,
Clark JW
,
Johnson BE
. Evaluation of statistical designs in phase I expansion cohorts: the Dana-Farber/Harvard Cancer Center experience. J Natl Cancer Inst. 2014 Jul; 106(7).
PMID:
24963024
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Hong TS
,
Ryan DP
, Borger DR,
Blaszkowsky LS
,
Yeap BY
, Ancukiewicz M,
Deshpande V
, Shinagare S,
Wo JY
,
Boucher Y
, Wadlow RC, Kwak EL, Allen JN,
Clark JW
, Zhu AX, Ferrone CR,
Mamon HJ
, Adams J, Winrich B, Grillo T,
Jain RK
,
DeLaney TF
,
Fernandez-del Castillo C
,
Duda DG
. A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine followed by early surgery for resectable pancreatic ductal adenocarcinoma. Int J Radiat Oncol Biol Phys. 2014 Jul 15; 89(4):830-8.
PMID:
24867540
.
Citations:
41
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
CT
Clinical Trials
Cleary JM
,
Rodig S
, Barr PM,
Shinagare AB
,
Clark JW
,
Shapiro GI
,
Armand P
. Crizotinib as salvage and maintenance with allogeneic stem cell transplantation for refractory anaplastic large cell lymphoma. J Natl Compr Canc Netw. 2014 Mar 01; 12(3):323-6; quiz 326.
PMID:
24616538
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Russo AL
,
Ryan DP
, Borger DR,
Wo JY
, Szymonifka J, Liang WY, Kwak EL,
Blaszkowsky LS
,
Clark JW
, Allen JN, Zhu AX,
Berger DL
,
Cusack JC
,
Mamon HJ
,
Haigis KM
,
Hong TS
. Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer. J Gastrointest Cancer. 2014 Mar; 45(1):34-9.
PMID:
24006244
.
Citations:
16
Fields:
Gas
Gastroenterology
Neo
Neoplasms
Translation:
Humans
Borger DR,
Goyal L
, Yau T, Poon RT, Ancukiewicz M,
Deshpande V
,
Christiani DC
, Liebman HM, Yang H, Kim H, Yen K, Faris JE,
Iafrate AJ
, Kwak EL,
Clark JW
, Allen JN,
Blaszkowsky LS
, Murphy JE, Saha SK,
Hong TS
,
Wo JY
, Ferrone CR,
Tanabe KK
, Bardeesy N, Straley KS, Agresta S, Schenkein DP,
Ellisen LW
,
Ryan DP
, Zhu AX. Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma. Clin Cancer Res. 2014 Apr 01; 20(7):1884-90.
PMID:
24478380
; PMCID:
PMC4107454
.
Citations:
52
Fields:
Neo
Neoplasms
Translation:
Humans
Coffee AL, Sulak PJ, Hill AJ, Hansen DJ, Kuehl TJ,
Clark JW
. Extended cycle combined oral contraceptives and prophylactic frovatriptan during the hormone-free interval in women with menstrual-related migraines. J Womens Health (Larchmt). 2014 Apr; 23(4):310-7.
PMID:
24450487
.
Citations:
9
Fields:
Gyn
Gynecology
Wom
Women's Health
Translation:
Humans
Goyal L
,
Supko JG
, Berlin J,
Blaszkowsky LS
, Carpenter A, Heuman DM, Hilderbrand SL, Stuart KE, Cotler S, Senzer NN, Chan E, Berg CL,
Clark JW
, Hezel AF,
Ryan DP
, Zhu AX. Phase 1 study of N(1),N(11)-diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma. Cancer Chemother Pharmacol. 2013 Dec; 72(6):1305-14.
PMID:
24121453
.
Citations:
10
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Izar B,
Rotow J
,
Gainor J
,
Clark J
,
Chabner B
. Pharmacokinetics, clinical indications, and resistance mechanisms in molecular targeted therapies in cancer. Pharmacol Rev. 2013; 65(4):1351-95.
PMID:
24092887
.
Citations:
12
Fields:
Pha
Pharmacology
Translation:
Humans
Animals
Faris JE,
Blaszkowsky LS
,
McDermott S
, Guimaraes AR, Szymonifka J,
Huynh MA
, Ferrone CR, Wargo JA, Allen JN, Dias LE, Kwak EL,
Lillemoe KD
, Thayer SP, Murphy JE, Zhu AX, Sahani DV,
Wo JY
,
Clark JW
,
Fernandez-del Castillo C
,
Ryan DP
,
Hong TS
. FOLFIRINOX in locally advanced pancreatic cancer: the Massachusetts General Hospital Cancer Center experience. Oncologist. 2013; 18(5):543-8.
PMID:
23657686
.
Citations:
115
Fields:
Neo
Neoplasms
Translation:
Humans
Diamond JR, Salgia R, Varella-Garcia M, Kanteti R, LoRusso PM,
Clark JW
, Xu LG, Wilner K, Eckhardt SG, Ching KA, Lira ME, Schoenmakers EF, Christensen JG, Camidge DR. Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma. J Clin Oncol. 2013 Jun 01; 31(16):e254-8.
PMID:
23610116
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans