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Robert Patrick Giugliano, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Douketis JD, Murphy SA, Antman EM, Grip LT, Mercuri MF, Ruff CT, Weitz JI, Braunwald E, Giugliano RP. Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial. Thromb Haemost. 2018 May 03. PMID: 29723874.
    View in: PubMed
  2. Bohula EA, Giugliano RP, Leiter LA, Verma S, Park JG, Sever PS, Pineda AL, Honarpour N, Wang H, Murphy SA, Keech A, Pedersen TR, Sabatine MS. Inflammatory and Cholesterol Risk in the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Patients With Elevated Risk). Circulation. 2018 Mar 12. PMID: 29530884.
    View in: PubMed
  3. Giugliano RP, Keech AC, Sever PS, Pedersen TR, Sabatine MS. Clinical benefits of evolocumab appear less than hoped - Authors' reply. Lancet. 2018 Mar 10; 391(10124):934-935. PMID: 29536853.
    View in: PubMed
  4. Cavallari I, Ruff CT, Nordio F, Deenadayalu N, Shi M, Lanz H, Rutman H, Mercuri MF, Antman EM, Braunwald E, Giugliano RP. Clinical events after interruption of anticoagulation in patients with atrial fibrillation: An analysis from the ENGAGE AF-TIMI 48 trial. Int J Cardiol. 2018 Apr 15; 257:102-107. PMID: 29395361.
    View in: PubMed
  5. Giugliano RP, Cannon CP, Blazing MA, Nicolau JC, Corbalán R, Špinar J, Park JG, White JA, Bohula EA, Braunwald E. Benefit of Adding Ezetimibe to Statin Therapy on Cardiovascular Outcomes and Safety in Patients With Versus Without Diabetes Mellitus: Results From IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial). Circulation. 2018 Apr 10; 137(15):1571-1582. PMID: 29263150.
    View in: PubMed
  6. Giugliano RP, Keech A, Murphy SA, Huber K, Tokgozoglu SL, Lewis BS, Ferreira J, Pineda AL, Somaratne R, Sever PS, Pedersen TR, Sabatine MS. Clinical Efficacy and Safety of Evolocumab in High-Risk Patients Receiving a Statin: Secondary Analysis of Patients With Low LDL Cholesterol Levels and in Those Already Receiving a Maximal-Potency Statin in a Randomized Clinical Trial. JAMA Cardiol. 2017 Dec 01; 2(12):1385-1391. PMID: 29117276.
    View in: PubMed
  7. Wang KL, Chiu CC, Giugliano RP, Tan DS, Lin CY, Lai EY, Goto S, Chiang CE. Drug Class, Renal Elimination, and Outcomes of Direct Oral Anticoagulants in Asian Patients: A Meta-Analysis. J Stroke Cerebrovasc Dis. 2018 Apr; 27(4):857-864. PMID: 29239808.
    View in: PubMed
  8. Kato ET, Cannon CP, Blazing MA, Bohula E, Guneri S, White JA, Murphy SA, Park JG, Braunwald E, Giugliano RP. Efficacy and Safety of Adding Ezetimibe to Statin Therapy Among Women and Men: Insight From IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial). J Am Heart Assoc. 2017 Nov 18; 6(11). PMID: 29151034.
    View in: PubMed
  9. Giugliano RP, Sabatine MS, Ott BR. Cognitive Function in a Randomized Trial of Evolocumab. N Engl J Med. 2017 11 16; 377(20):1997. PMID: 29141161.
    View in: PubMed
  10. Giugliano RP, Sabatine MS, Ott BR. Cognitive Function in a Randomized Trial of Evolocumab. N Engl J Med. 2017 Nov 16; 377(20):1997. PMID: 29327884.
    View in: PubMed
  11. Bonaca MP, Nault P, Giugliano RP, Keech AC, Pineda AL, Kanevsky E, Kuder J, Murphy SA, Jukema JW, Lewis BS, Tokgozoglu L, Somaratne R, Sever PS, Pedersen TR, Sabatine MS. Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk). Circulation. 2018 Jan 23; 137(4):338-350. PMID: 29133605.
    View in: PubMed
  12. Plitt A, McGuire DK, Giugliano RP. Major Bleeding in Patients With Diabetes and Atrial Fibrillation Treated With New Oral Anticoagulants-Reply. JAMA Cardiol. 2017 Oct 01; 2(10):1168. PMID: 28658488.
    View in: PubMed
  13. Fonarow GC, Keech AC, Pedersen TR, Giugliano RP, Sever PS, Lindgren P, van Hout B, Villa G, Qian Y, Somaratne R, Sabatine MS. Cost-effectiveness of Evolocumab Therapy for Reducing Cardiovascular Events in Patients With Atherosclerotic Cardiovascular Disease. JAMA Cardiol. 2017 Oct 01; 2(10):1069-1078. PMID: 28832867.
    View in: PubMed
  14. Abell JE, Laing SM, Barker TC, Norry EC, Starzyk K, Goodman SG, Dellborg M, Steg PG, Giugliano RP. Adjunctive use of anticoagulants at the time of percutaneous coronary intervention in patients with an acute coronary syndrome treated with fondaparinux: a multinational retrospective review. Eur Heart J Cardiovasc Pharmacother. 2017 Oct 01; 3(4):214-220. PMID: 28430984.
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  15. Bohula EA, Wiviott SD, Giugliano RP, Blazing MA, Park JG, Murphy SA, White JA, Mach F, Van de Werf F, Dalby AJ, White HD, Tershakovec AM, Cannon CP, Braunwald E. Prevention of Stroke with the Addition of Ezetimibe to Statin Therapy in Patients With Acute Coronary Syndrome in IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial). Circulation. 2017 Dec 19; 136(25):2440-2450. PMID: 28972004.
    View in: PubMed
  16. Fanaroff AC, Roe MT, Clare RM, Lokhnygina Y, Navar AM, Giugliano RP, Wiviott SD, Tershakovec AM, Braunwald E, Blazing MA. Competing Risks of Cardiovascular Versus Noncardiovascular Death During Long-Term Follow-Up After Acute Coronary Syndromes. J Am Heart Assoc. 2017 Sep 18; 6(9). PMID: 28923989.
    View in: PubMed
  17. Sabatine MS, Leiter LA, Wiviott SD, Giugliano RP, Deedwania P, De Ferrari GM, Murphy SA, Kuder JF, Gouni-Berthold I, Lewis BS, Handelsman Y, Pineda AL, Honarpour N, Keech AC, Sever PS, Pedersen TR. Cardiovascular safety and efficacy of the PCSK9 inhibitor evolocumab in patients with and without diabetes and the effect of evolocumab on glycaemia and risk of new-onset diabetes: a prespecified analysis of the FOURIER randomised controlled trial. Lancet Diabetes Endocrinol. 2017 Dec; 5(12):941-950. PMID: 28927706.
    View in: PubMed
  18. Sabatine MS, Giugliano RP. Low-Density Lipoprotein Cholesterol Treatment in the Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor Era: Getting Back on Target. JAMA Cardiol. 2017 Sep 01; 2(9):935-936. PMID: 28768310.
    View in: PubMed
  19. Bohula EA, Morrow DA, Giugliano RP, Cannon CP, Braunwald E. Reply: Ezetimibe, Risk Stratification, and Secondary Prevention. J Am Coll Cardiol. 2017 Aug 29; 70(9):1200. PMID: 28838375.
    View in: PubMed
  20. Giugliano RP, Pedersen TR, Park JG, De Ferrari GM, Gaciong ZA, Ceska R, Toth K, Gouni-Berthold I, Lopez-Miranda J, Schiele F, Mach F, Ott BR, Kanevsky E, Pineda AL, Somaratne R, Wasserman SM, Keech AC, Sever PS, Sabatine MS. Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial. Lancet. 2017 Oct 28; 390(10106):1962-1971. PMID: 28859947.
    View in: PubMed
  21. Sabatine MS, Giugliano RP, Pedersen TR. Evolocumab in Patients with Cardiovascular Disease. N Engl J Med. 2017 08 24; 377(8):787-8. PMID: 28834471.
    View in: PubMed
  22. Giugliano RP, Mach F, Zavitz K, Kurtz C, Im K, Kanevsky E, Schneider J, Wang H, Keech A, Pedersen TR, Sabatine MS, Sever PS, Robinson JG, Honarpour N, Wasserman SM, Ott BR. Cognitive Function in a Randomized Trial of Evolocumab. N Engl J Med. 2017 08 17; 377(7):633-643. PMID: 28813214.
    View in: PubMed
  23. Wang K, Li H, Kwong WJ, Antman EM, Ruff CT, Giugliano RP, Cohen DJ, Magnuson EA. Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF-TIMI 48 Trial. J Am Heart Assoc. 2017 Aug 11; 6(8). PMID: 28862934.
    View in: PubMed
  24. Eisen A, Ruff CT, Braunwald E, Hamershock RA, Lewis BS, Hassager C, Chao TF, Le Heuzey JY, Mercuri M, Rutman H, Antman EM, Giugliano RP. Digoxin Use and Subsequent Clinical Outcomes in Patients With Atrial Fibrillation With or Without Heart Failure in the ENGAGE AF-TIMI 48 Trial. J Am Heart Assoc. 2017 Jun 30; 6(7). PMID: 28666993.
    View in: PubMed
  25. Wang KL, Chiu CC, Su-Yin Tan D, Lin CY, Lai EY, Goto S, Giugliano RP, Chiang CE. Once- or twice-daily non-vitamin K antagonist oral anticoagulants in Asian patients with atrial fibrillation: A meta-analysis of randomized controlled trials. J Formos Med Assoc. 2017 Aug; 116(8):591-598. PMID: 28645443.
    View in: PubMed
  26. Steffel J, Ruff CT, Hamershock RA, Murphy SA, Senior R, Roy D, Lanz HJ, Mercuri MF, Antman EM, Giugliano RP. First experience with edoxaban and atrial fibrillation ablation - Insights from the ENGAGE AF-TIMI 48 trial. Int J Cardiol. 2017 Oct 01; 244:192-195. PMID: 28625512.
    View in: PubMed
  27. Koren MJ, Sabatine MS, Giugliano RP, Langslet G, Wiviott SD, Kassahun H, Ruzza A, Ma Y, Somaratne R, Raal FJ. Long-term Low-Density Lipoprotein Cholesterol-Lowering Efficacy, Persistence, and Safety of Evolocumab in Treatment of Hypercholesterolemia: Results Up to 4 Years From the Open-Label OSLER-1 Extension Study. JAMA Cardiol. 2017 Jun 01; 2(6):598-607. PMID: 28291870.
    View in: PubMed
  28. Vilain KA, Yang MC, Hui Tan EC, Wang K, Li H, Hsu WH, Giugliano RP, Cohen DJ, Magnuson EA. Cost-Effectiveness of Edoxaban vs. Warfarin in Patients with Atrial Fibrillation Based on Results of the ENGAGE AF - TIMI 48 Trial: Taiwanese Perspective. Value Health Reg Issues. 2017 May; 12:74-83. PMID: 28648320.
    View in: PubMed
  29. Giugliano RP, Wiviott SD, Blazing MA, De Ferrari GM, Park JG, Murphy SA, White JA, Tershakovec AM, Cannon CP, Braunwald E. Long-term Safety and Efficacy of Achieving Very Low Levels of Low-Density Lipoprotein Cholesterol : A Prespecified Analysis of the IMPROVE-IT Trial. JAMA Cardiol. 2017 May 01; 2(5):547-555. PMID: 28291866.
    View in: PubMed
  30. Desai NR, Giugliano RP, Wasserman SM, Gibbs JP, Liu T, Scott R, Sabatine MS. Association Between Circulating Baseline Proprotein Convertase Subtilisin Kexin Type 9 Levels and Efficacy of Evolocumab. JAMA Cardiol. 2017 May 01; 2(5):556-560. PMID: 28122070.
    View in: PubMed
  31. Pokharel Y, Chinnakondepalli K, Vilain K, Wang K, Mark DB, Davies G, Blazing MA, Giugliano RP, Braunwald E, Cannon CP, Cohen DJ, Magnuson EA. Impact of Ezetimibe on the Rate of Cardiovascular-Related Hospitalizations and Associated Costs Among Patients With a Recent Acute Coronary Syndrome: Results From the IMPROVE-IT Trial (Improved Reduction of Outcomes: Vytorin Efficacy International Trial). Circ Cardiovasc Qual Outcomes. 2017 May; 10(5). PMID: 28506979.
    View in: PubMed
  32. Koshizaka M, Lopes RD, Newby LK, Clare RM, Schulte PJ, Tricoci P, Mahaffey KW, Ogawa H, Moliterno DJ, Giugliano RP, Huber K, James S, Harrington RA, Alexander JH. Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites. Am J Med. 2017 Oct; 130(10):1170-1176. PMID: 28396226.
    View in: PubMed
  33. Plitt A, McGuire DK, Giugliano RP. Atrial Fibrillation, Type 2 Diabetes, and Non-Vitamin K Antagonist Oral Anticoagulants: A Review. JAMA Cardiol. 2017 Apr 01; 2(4):442-448. PMID: 28122078.
    View in: PubMed
  34. De Caterina R, Renda G, Carnicelli AP, Nordio F, Trevisan M, Mercuri MF, Ruff CT, Antman EM, Braunwald E, Giugliano RP. Valvular Heart Disease Patients on Edoxaban or Warfarin in the ENGAGE AF-TIMI 48 Trial. J Am Coll Cardiol. 2017 Mar 21; 69(11):1372-1382. PMID: 28302288.
    View in: PubMed
  35. Renda G, Ricci F, Giugliano RP, De Caterina R. Non-Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease. J Am Coll Cardiol. 2017 Mar 21; 69(11):1363-1371. PMID: 28302287.
    View in: PubMed
  36. Fanola CL, Giugliano RP, Ruff CT, Trevisan M, Nordio F, Mercuri MF, Antman EM, Braunwald E. A novel risk prediction score in atrial fibrillation for a net clinical outcome from the ENGAGE AF-TIMI 48 randomized clinical trial. Eur Heart J. 2017 Mar 21; 38(12):888-896. PMID: 28064150.
    View in: PubMed
  37. Sabatine MS, Giugliano RP, Keech AC, Honarpour N, Wiviott SD, Murphy SA, Kuder JF, Wang H, Liu T, Wasserman SM, Sever PS, Pedersen TR. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. N Engl J Med. 2017 05 04; 376(18):1713-1722. PMID: 28304224.
    View in: PubMed
  38. Bohula EA, Morrow DA, Giugliano RP, Blazing MA, He P, Park JG, Murphy SA, White JA, Kesaniemi YA, Pedersen TR, Brady AJ, Mitchel Y, Cannon CP, Braunwald E. Atherothrombotic Risk Stratification and Ezetimibe for Secondary Prevention. J Am Coll Cardiol. 2017 Feb 28; 69(8):911-921. PMID: 28231942.
    View in: PubMed
  39. Carnicelli AP, De Caterina R, Halperin JL, Renda G, Ruff CT, Trevisan M, Nordio F, Mercuri MF, Antman E, Giugliano RP. Edoxaban for the Prevention of Thromboembolism in Patients With Atrial Fibrillation and Bioprosthetic Valves. Circulation. 2017 Mar 28; 135(13):1273-1275. PMID: 28209729.
    View in: PubMed
  40. Giugliano RP, Mach F, Zavitz K, Kurtz C, Schneider J, Wang H, Keech A, Pedersen TR, Sabatine MS, Sever PS, Honarpour N, Wasserman SM, Ott BR. Design and rationale of the EBBINGHAUS trial: A phase 3, double-blind, placebo-controlled, multicenter study to assess the effect of evolocumab on cognitive function in patients with clinically evident cardiovascular disease and receiving statin background lipid-lowering therapy-A cognitive study of patients enrolled in the FOURIER trial. Clin Cardiol. 2017 Feb; 40(2):59-65. PMID: 28207168.
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  41. Farhan S, Clare RM, Jarai R, Giugliano RP, Lokhnygina Y, Harrington RA, Kristin Newby L, Huber K. Fasting glucose, NT-proBNP, treatment with eptifibatide, and outcomes in non-ST-segment elevation acute coronary syndromes: An analysis from EARLY ACS. Int J Cardiol. 2017 Apr 01; 232:264-270. PMID: 28089149.
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  42. Wang KL, Büller HR, Goto S, Lin CY, Lai EY, Chiu CC, Chiang CE, Giugliano RP. Extracranial arterial and venous thromboembolism in patients with atrial fibrillation: A meta-analysis of randomized controlled trials. Heart Rhythm. 2017 04; 14(4):599-605. PMID: 28062249.
    View in: PubMed
  43. Link MS, Giugliano RP, Ruff CT, Scirica BM, Huikuri H, Oto A, Crompton AE, Murphy SA, Lanz H, Mercuri MF, Antman EM, Braunwald E. Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48). Circ Arrhythm Electrophysiol. 2017 Jan; 10(1). PMID: 28077507.
    View in: PubMed
  44. Steen DL, Khan I, Becker L, Foody JM, Gorcyca K, Sanchez RJ, Giugliano RP. Patterns and predictors of lipid-lowering therapy in patients with atherosclerotic cardiovascular disease and/or diabetes mellitus in 2014: Insights from a large US managed-care population. Clin Cardiol. 2017 Mar; 40(3):155-162. PMID: 28026031.
    View in: PubMed
  45. Ference BA, Robinson JG, Brook RD, Catapano AL, Chapman MJ, Neff DR, Voros S, Giugliano RP, Davey Smith G, Fazio S, Sabatine MS. Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes. N Engl J Med. 2016 12 01; 375(22):2144-2153. PMID: 27959767.
    View in: PubMed
  46. Ruff CT, Giugliano RP, Braunwald E, Murphy SA, Brown K, Jarolim P, Mercuri M, Antman EM, Morrow DA. Cardiovascular Biomarker Score and Clinical Outcomes in Patients With Atrial Fibrillation: A Subanalysis of the ENGAGE AF-TIMI 48 Randomized Clinical Trial. JAMA Cardiol. 2016 Dec 01; 1(9):999-1006. PMID: 27706467.
    View in: PubMed
  47. Eisen A, Giugliano RP. Advances in the field of proprotein convertase subtilisin kexin type 9 inhibitors. Curr Opin Cardiol. 2016 Nov; 31(6):644-653. PMID: 27661220.
    View in: PubMed
  48. Simon TG, Corey KE, Chung RT, Giugliano R. Cardiovascular Risk Reduction in Patients with Nonalcoholic Fatty Liver Disease: The Potential Role of Ezetimibe. Dig Dis Sci. 2016 12; 61(12):3425-3435. PMID: 27714510.
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  49. Massaro A, Giugliano RP, Norrving B, Oto A, Veltkamp R. Overcoming global challenges in stroke prophylaxis in atrial fibrillation: The role of non-vitamin K antagonist oral anticoagulants. Int J Stroke. 2016 12; 11(9):950-967. PMID: 27703066.
    View in: PubMed
  50. Plitt A, Ruff CT, Giugliano RP. Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation. Hematol Oncol Clin North Am. 2016 10; 30(5):1019-34. PMID: 27637305.
    View in: PubMed
  51. Silverman MG, Ference BA, Im K, Wiviott SD, Giugliano RP, Grundy SM, Braunwald E, Sabatine MS. Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis. JAMA. 2016 Sep 27; 316(12):1289-97. PMID: 27673306.
    View in: PubMed
  52. Blazing MA, Giugliano RP, de Lemos JA, Cannon CP, Tonkin A, Ballantyne CM, Lewis BS, Musliner TA, Tershakovec AM, Lokhnygina Y, White JA, Reist C, McCagg A, Braunwald E. On-treatment analysis of the Improved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT). Am Heart J. 2016 Dec; 182:89-96. PMID: 27914504.
    View in: PubMed
  53. Steffel J, Giugliano RP, Braunwald E, Murphy SA, Mercuri M, Choi Y, Aylward P, White H, Zamorano JL, Antman EM, Ruff CT. Edoxaban Versus Warfarin in Atrial Fibrillation Patients at Risk of Falling: ENGAGE AF-TIMI 48 Analysis. J Am Coll Cardiol. 2016 Sep 13; 68(11):1169-1178. PMID: 27609678.
    View in: PubMed
  54. Wang KL, Giugliano RP, Goto S, Chiu CC, Lin CY, Lai EY, Chiang CE. Standard dose versus low dose non-vitamin K antagonist oral anticoagulants in Asian patients with atrial fibrillation: A meta-analysis of contemporary randomized controlled trials. Heart Rhythm. 2016 12; 13(12):2340-2347. PMID: 27614026.
    View in: PubMed
  55. Savarese G, Giugliano RP, Rosano GM, McMurray J, Magnani G, Filippatos G, Dellegrottaglie S, Lund LH, Trimarco B, Perrone-Filardi P. Efficacy and Safety of Novel Oral Anticoagulants in Patients With Atrial Fibrillation and Heart Failure: A Meta-Analysis. JACC Heart Fail. 2016 Nov; 4(11):870-880. PMID: 27614940.
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  56. Eisen A, Giugliano RP, Braunwald E. Updates on Acute Coronary Syndrome: A Review. JAMA Cardiol. 2016 Sep 01; 1(6):718-30. PMID: 27438381.
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  57. Eisen A, Cannon CP, Blazing MA, Bohula EA, Park JG, Murphy SA, White JA, Giugliano RP, Braunwald E. The benefit of adding ezetimibe to statin therapy in patients with prior coronary artery bypass graft surgery and acute coronary syndrome in the IMPROVE-IT trial. Eur Heart J. 2016 Dec 21; 37(48):3576-3584. PMID: 27569841.
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  58. Carnicelli AP, O'Gara PT, Giugliano RP. Anticoagulation After Heart Valve Replacement or Transcatheter Valve Implantation. Am J Cardiol. 2016 Nov 01; 118(9):1419-1426. PMID: 27666180.
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  59. Bedeir K, Giugliano RP, Ramlawi B. Chronic anticoagulation in non-valvular atrial fibrillation: Where things stand. Int J Cardiol. 2016 Nov 01; 222:615-619. PMID: 27521536.
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  60. Murphy SA, Cannon CP, Blazing MA, Giugliano RP, Tershakovec AM, Braunwald E. Reply: Personalize and Optimize Lipid-Lowering Therapies. J Am Coll Cardiol. 2016 Jul 19; 68(3):326. PMID: 27417014.
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  61. Ruff CT, Giugliano RP, Antman EM. Management of Bleeding With Non-Vitamin K Antagonist Oral Anticoagulants in the Era of Specific Reversal Agents. Circulation. 2016 Jul 19; 134(3):248-61. PMID: 27436881.
    View in: PubMed
  62. Eisen A, Ruff CT, Braunwald E, Nordio F, Corbalán R, Dalby A, Dorobantu M, Mercuri M, Lanz H, Rutman H, Wiviott SD, Antman EM, Giugliano RP. Sudden Cardiac Death in Patients With Atrial Fibrillation: Insights From the ENGAGE AF-TIMI 48 Trial. J Am Heart Assoc. 2016 Jul 08; 5(7). PMID: 27402235.
    View in: PubMed
  63. Rost NS, Giugliano RP, Ruff CT, Murphy SA, Crompton AE, Norden AD, Silverman S, Singhal AB, Nicolau JC, SomaRaju B, Mercuri MF, Antman EM, Braunwald E. Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events: Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48). Stroke. 2016 08; 47(8):2075-82. PMID: 27387994.
    View in: PubMed
  64. Bohula EA, Giugliano RP, Ruff CT, Kuder JF, Murphy SA, Antman EM, Braunwald E. Impact of Renal Function on Outcomes With Edoxaban in the ENGAGE AF-TIMI 48 Trial. Circulation. 2016 Jul 05; 134(1):24-36. PMID: 27358434.
    View in: PubMed
  65. Eisen A, Giugliano RP. Antiplatelet and Anticoagulation Treatment in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: Comparison of the Updated North American and European Guidelines. Cardiol Rev. 2016 Jul-Aug; 24(4):170-6. PMID: 26186386.
    View in: PubMed
  66. Murphy SA, Cannon CP, Blazing MA, Giugliano RP, Tershakovec AM, Braunwald E. Reply: Adding Ezetimibe to Simvastatin for the Secondary Prevention of Cardiovascular Disease: Is it Useful? J Am Coll Cardiol. 2016 Jun 28; 67(25):3025-6. PMID: 27339506.
    View in: PubMed
  67. Magnani G, Giugliano RP, Ruff CT, Murphy SA, Nordio F, Metra M, Moccetti T, Mitrovic V, Shi M, Mercuri M, Antman EM, Braunwald E. Efficacy and safety of edoxaban compared with warfarin in patients with atrial fibrillation and heart failure: insights from ENGAGE AF-TIMI 48. Eur J Heart Fail. 2016 09; 18(9):1153-61. PMID: 27349698.
    View in: PubMed
  68. Chan KE, Giugliano RP, Patel MR, Abramson S, Jardine M, Zhao S, Perkovic V, Maddux FW, Piccini JP. Nonvitamin K Anticoagulant Agents in Patients With Advanced Chronic Kidney Disease or on Dialysis With AF. J Am Coll Cardiol. 2016 Jun 21; 67(24):2888-99. PMID: 27311528.
    View in: PubMed
  69. Daaboul Y, Korjian S, Weaver WD, Kloner RA, Giugliano RP, Carr J, Neal BJ, Chi G, Cochet M, Goodell L, Michalak N, Rusowicz-Orazem L, Alkathery T, Allaham H, Routray S, Szlosek D, Jain P, Gibson CM. Relation of Left Ventricular Mass and Infarct Size in Anterior Wall ST-Segment Elevation Acute Myocardial Infarction (from the EMBRACE STEMI Clinical Trial). Am J Cardiol. 2016 Sep 01; 118(5):625-31. PMID: 27392509.
    View in: PubMed
  70. Renda G, Zimarino M, Ricci F, Piccini JP, Ezekowitz MD, Patel MR, Cappato R, Giugliano RP, De Caterina R. Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants After Cardioversion for Nonvalvular Atrial Fibrillation. Am J Med. 2016 Oct; 129(10):1117-1123.e2. PMID: 27262782.
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  71. Kato ET, Giugliano RP, Ruff CT, Koretsune Y, Yamashita T, Kiss RG, Nordio F, Murphy SA, Kimura T, Jin J, Lanz H, Mercuri M, Braunwald E, Antman EM. Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF-TIMI 48 Trial. J Am Heart Assoc. 2016 May 20; 5(5). PMID: 27207971; PMCID: PMC4889207.
  72. Ruff CT, Ansell JE, Becker RC, Benjamin EJ, Deicicchi DJ, Mark Estes NA, Ezekowitz MD, Fanikos J, Fareed J, Garcia D, Giugliano RP, Goldhaber SZ, Granger C, Healey JS, Hull R, Hylek EM, Libby P, Lopes RD, Mahaffey KW, Mega J, Piazza G, Sasahara AA, Sorond FA, Spyropoulos AC, Walenga JM, Weitz JI. North American Thrombosis Forum, AF Action Initiative Consensus Document. Am J Med. 2016 May; 129(5 Suppl):S1-S29. PMID: 27126598.
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  73. Raal FJ, Giugliano RP, Sabatine MS, Koren MJ, Blom D, Seidah NG, Honarpour N, Lira A, Xue A, Chiruvolu P, Jackson S, Di M, Peach M, Somaratne R, Wasserman SM, Scott R, Stein EA. PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role. J Lipid Res. 2016 06; 57(6):1086-96. PMID: 27102113; PMCID: PMC4878192 [Available on 06/01/17].
  74. Gupta DK, Giugliano RP, Ruff CT, Claggett B, Murphy S, Antman E, Mercuri MF, Braunwald E, Solomon SD. The Prognostic Significance of Cardiac Structure and Function in Atrial Fibrillation: The ENGAGE AF-TIMI 48 Echocardiographic Substudy. J Am Soc Echocardiogr. 2016 Jun; 29(6):537-44. PMID: 27106009; PMCID: PMC4893881 [Available on 06/01/17].
  75. Plitt A, Ezekowitz MD, De Caterina R, Nordio F, Peterson N, Giugliano RP. Cardioversion of Atrial Fibrillation in ENGAGE AF-TIMI 48. Clin Cardiol. 2016 Jun; 39(6):345-6. PMID: 27028520.
    View in: PubMed
  76. Bohula EA, Giugliano RP, Cannon CP, Zhou J, Murphy SA, White J, Tershakovec AM, Blazing MA, Braunwald E. Response to Letter Regarding Article, "Achievement of Dual Low-Density Lipoprotein Cholesterol and High-Sensitivity C-Reactive Protein Targets More Frequent With the Addition of Ezetimibe to Simvastatin and Associated With Better Outcomes in IMPROVE-IT". Circulation. 2016 Mar 29; 133(13):e463. PMID: 27022050.
    View in: PubMed
  77. Giugliano RP, Ruff CT, Wiviott SD, Nordio F, Murphy SA, Kappelhof JA, Shi M, Mercuri MF, Antman EM, Braunwald E. Mortality in Patients with Atrial Fibrillation Randomized to Edoxaban or Warfarin: Insights from the ENGAGE AF-TIMI 48 Trial. Am J Med. 2016 Aug; 129(8):850-857.e2. PMID: 26994510.
    View in: PubMed
  78. Kragholm K, Goldstein SA, Yang Q, Lopes RD, Schulte PJ, Bernacki GM, White HD, Mahaffey KW, Giugliano RP, Armstrong PW, Harrington RA, Tricoci P, Van de Werf F, Alexander JH, Alexander KP, Newby LK. Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials. Circulation. 2016 Apr 19; 133(16):1560-73. PMID: 26957532; PMCID: PMC4856566 [Available on 04/19/17].
  79. Xu H, Ruff CT, Giugliano RP, Murphy SA, Nordio F, Patel I, Shi M, Mercuri M, Antman EM, Braunwald E. Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF-TIMI48 Trial. J Am Heart Assoc. 2016 Feb 23; 5(2). PMID: 26908401; PMCID: PMC4802446.
  80. Yamashita T, Koretsune Y, Yang Y, Chen SA, Chung N, Shimada YJ, Kimura T, Miyazaki K, Abe K, Mercuri M, Ruff CT, Giugliano RP. Edoxaban vs. Warfarin in East Asian Patients With Atrial Fibrillation - An ENGAGE AF-TIMI 48 Subanalysis. Circ J. 2016; 80(4):860-9. PMID: 26888149.
    View in: PubMed
  81. Wheeler DS, Giugliano RP, Rangaswami J. Anticoagulation-related nephropathy. J Thromb Haemost. 2016 Mar; 14(3):461-7. PMID: 26670286.
    View in: PubMed
  82. Murphy SA, Cannon CP, Blazing MA, Giugliano RP, White JA, Lokhnygina Y, Reist C, Im K, Bohula EA, Isaza D, Lopez-Sendon J, Dellborg M, Kher U, Tershakovec AM, Braunwald E. Reduction in Total Cardiovascular Events With Ezetimibe/Simvastatin Post-Acute Coronary Syndrome: The IMPROVE-IT Trial. J Am Coll Cardiol. 2016 Feb 02; 67(4):353-361. PMID: 26821621.
    View in: PubMed
  83. Wayangankar SA, Roe MT, Chen AY, Gupta RS, Giugliano RP, Newby LK, de Lemos JA, Alexander KP, Sanborn TA, Saucedo JF. Trends in use of anti-thrombotic agents and outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI) managed with an invasive strategy. Indian Heart J. 2016 Jul-Aug; 68(4):464-72. PMID: 27543467; PMCID: PMC4990733 [Available on 07/01/17].
  84. Sabatine MS, Giugliano RP, Keech A, Honarpour N, Wang H, Liu T, Wasserman SM, Scott R, Sever PS, Pedersen TR. Rationale and design of the Further cardiovascular OUtcomes Research with PCSK9 Inhibition in subjects with Elevated Risk trial. Am Heart J. 2016 Mar; 173:94-101. PMID: 26920601.
    View in: PubMed
  85. Eisen A, Giugliano RP, Ruff CT, Nordio F, Gogia HS, Awasty VR, Henderson DA, Mercuri MF, Rutman H, Antman EM, Braunwald E. Edoxaban vs warfarin in patients with nonvalvular atrial fibrillation in the US Food and Drug Administration approval population: An analysis from the Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48 (ENGAGE AF-TIMI 48) trial. Am Heart J. 2016 Feb; 172:144-51. PMID: 26856226.
    View in: PubMed
  86. Wadhera RK, Steen DL, Khan I, Giugliano RP, Foody JM. A review of low-density lipoprotein cholesterol, treatment strategies, and its impact on cardiovascular disease morbidity and mortality. J Clin Lipidol. 2016 May-Jun; 10(3):472-89. PMID: 27206934.
    View in: PubMed
  87. Gibson CM, Giugliano RP, Kloner RA, Bode C, Tendera M, Jánosi A, Merkely B, Godlewski J, Halaby R, Korjian S, Daaboul Y, Chakrabarti AK, Spielman K, Neal BJ, Weaver WD. EMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients undergoing primary percutaneous coronary intervention. Eur Heart J. 2016 04 21; 37(16):1296-303. PMID: 26586786.
    View in: PubMed
  88. Sarma A, Giugliano RP. Current and developing strategies for monitoring and reversing direct oral anticoagulants in patients with non-valvular atrial fibrillation. Hosp Pract (1995). 2015; 43(5):258-67. PMID: 26559852.
    View in: PubMed
  89. Halim SA, Clare RM, Newby LK, Lokhnygina Y, Schweiger MJ, Hof AW, Hochman JS, James SK, White HD, Widimsky P, Betriu A, Bode C, Giugliano RP, Harrington RA, Zeymer U. Frequency, clinical and angiographic characteristics, and outcomes of high-risk non-ST-segment elevation acute coronary syndromes patients with left circumflex culprit lesions. Int J Cardiol. 2016 Jan 15; 203:708-13. PMID: 26587725.
    View in: PubMed
  90. Shimada YJ, Yamashita T, Koretsune Y, Kimura T, Abe K, Sasaki S, Mercuri M, Ruff CT, Giugliano RP. Effects of Regional Differences in Asia on Efficacy and Safety of Edoxaban Compared With Warfarin--Insights From the ENGAGE AF-TIMI 48 Trial. Circ J. 2015; 79(12):2560-7. PMID: 26460886.
    View in: PubMed
  91. Magnuson EA, Vilain K, Wang K, Li H, Kwong WJ, Antman EM, Ruff CT, Giugliano RP, Cohen DJ. Cost-effectiveness of edoxaban vs warfarin in patients with atrial fibrillation based on results of the ENGAGE AF-TIMI 48 trial. Am Heart J. 2015 Dec; 170(6):1140-50. PMID: 26678636.
    View in: PubMed
  92. Rossi JE, Noll A, Bergmark B, McCabe JM, Nemer D, Okada DR, Vasudevan A, Davidson M, Welt F, Eisenhauer A, Shah P, Giugliano R. Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience. Cardiol Ther. 2015 Dec; 4(2):197-201. PMID: 26399647; PMCID: PMC4675746.
  93. Pokorney SD, Radder C, Schulte PJ, Al-Khatib SM, Tricocci P, Van de Werf F, James SK, Cannon CP, Armstrong PW, White HD, Califf RM, Gibson CM, Giugliano RP, Wallentin L, Mahaffey KW, Harrington RA, Newby LK, Piccini JP. High-degree atrioventricular block, asystole, and electro-mechanical dissociation complicating non-ST-segment elevation myocardial infarction. Am Heart J. 2016 Jan; 171(1):25-32. PMID: 26699597; PMCID: PMC4692180 [Available on 01/01/17].
  94. Bohula EA, Giugliano RP, Cannon CP, Zhou J, Murphy SA, White JA, Tershakovec AM, Blazing MA, Braunwald E. Achievement of dual low-density lipoprotein cholesterol and high-sensitivity C-reactive protein targets more frequent with the addition of ezetimibe to simvastatin and associated with better outcomes in IMPROVE-IT. Circulation. 2015 Sep 29; 132(13):1224-33. PMID: 26330412.
    View in: PubMed
  95. Kragholm K, Halim SA, Yang Q, Schulte PJ, Hochman JS, Melloni C, Mahaffey KW, Moliterno DJ, Harrington RA, White HD, Armstrong PW, Ohman EM, Van de Werf F, Tricoci P, Alexander JH, Giugliano RP, Newby LK. Sex-Stratified Trends in Enrollment, Patient Characteristics, Treatment, and Outcomes Among Non-ST-Segment Elevation Acute Coronary Syndrome Patients: Insights From Clinical Trials Over 17 Years. Circ Cardiovasc Qual Outcomes. 2015 Jul; 8(4):357-67. PMID: 26152683; PMCID: PMC4512844.
  96. Nicolau JC, Franci A, Barbosa CJ, Baracioli LM, Franken M, Furtado RH, Giraldez RR, Ganem F, Lima FG, Menezes FR, Arantes FB, Ramires JA, Filho RK, Giugliano RP. Influence of proven oral therapies in the very old with acute coronary syndromes: A 15 year experience. Int J Cardiol. 2015 Nov 01; 198:213-5. PMID: 26173060.
    View in: PubMed
  97. Geller BJ, Giugliano RP, Braunwald E, Murphy SA, Hanyok JJ, Jin J, Mercuri M, Antman EM, Ruff CT. Systemic, noncerebral, arterial embolism in 21,105 patients with atrial fibrillation randomized to edoxaban or warfarin: results from the Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction Study 48 trial. Am Heart J. 2015 Oct; 170(4):669-74. PMID: 26386790.
    View in: PubMed
  98. Giugliano RP, Sabatine MS. Are PCSK9 Inhibitors the Next Breakthrough in the Cardiovascular Field? J Am Coll Cardiol. 2015 Jun 23; 65(24):2638-2651. PMID: 26088304.
    View in: PubMed
  99. Cannon CP, Blazing MA, Giugliano RP, McCagg A, White JA, Theroux P, Darius H, Lewis BS, Ophuis TO, Jukema JW, De Ferrari GM, Ruzyllo W, De Lucca P, Im K, Bohula EA, Reist C, Wiviott SD, Tershakovec AM, Musliner TA, Braunwald E, Califf RM. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med. 2015 Jun 18; 372(25):2387-97. PMID: 26039521.
    View in: PubMed
  100. Steffel J, Giugliano RP, Braunwald E, Murphy SA, Atar D, Heidbuchel H, Camm AJ, Antman EM, Ruff CT. Edoxaban vs. warfarin in patients with atrial fibrillation on amiodarone: a subgroup analysis of the ENGAGE AF-TIMI 48 trial. Eur Heart J. 2015 Sep 01; 36(33):2239-45. PMID: 25971288.
    View in: PubMed
  101. Kovacs RJ, Flaker GC, Saxonhouse SJ, Doherty JU, Birtcher KK, Cuker A, Davidson BL, Giugliano RP, Granger CB, Jaffer AK, Mehta BH, Nutescu E, Williams KA. Practical management of anticoagulation in patients with atrial fibrillation. J Am Coll Cardiol. 2015 Apr 07; 65(13):1340-1360. PMID: 25835447.
    View in: PubMed
  102. Sabatine MS, Giugliano RP, Wiviott SD, Raal FJ, Blom DJ, Robinson J, Ballantyne CM, Somaratne R, Legg J, Wasserman SM, Scott R, Koren MJ, Stein EA. Efficacy and safety of evolocumab in reducing lipids and cardiovascular events. N Engl J Med. 2015 Apr 16; 372(16):1500-9. PMID: 25773607.
    View in: PubMed
  103. Giugliano RP, Zeymer U, Menown I. Editors' Picks for 2014 and a Look into the Future. Cardiol Ther. 2015 Jun; 4(1):1-3. PMID: 25766962; PMCID: PMC4472644.
  104. Mega JL, Walker JR, Ruff CT, Vandell AG, Nordio F, Deenadayalu N, Murphy SA, Lee J, Mercuri MF, Giugliano RP, Antman EM, Braunwald E, Sabatine MS. Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial. Lancet. 2015 Jun 06; 385(9984):2280-7. PMID: 25769357.
    View in: PubMed
  105. Ruff CT, Giugliano RP, Braunwald E, Morrow DA, Murphy SA, Kuder JF, Deenadayalu N, Jarolim P, Betcher J, Shi M, Brown K, Patel I, Mercuri M, Antman EM. Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial. Lancet. 2015 Jun 06; 385(9984):2288-95. PMID: 25769361.
    View in: PubMed
  106. Grinstein J, Bonaca MP, Jarolim P, Conrad MJ, Bohula-May E, Deenadayalu N, Braunwald E, Giugliano RP, Newby LK, Sabatine MS, Morrow DA. Prognostic implications of low level cardiac troponin elevation using high-sensitivity cardiac troponin T. Clin Cardiol. 2015 Apr; 38(4):230-5. PMID: 25737394.
    View in: PubMed
  107. Wessler JD, Giugliano RP. Risk of thrombocytopenia with glycoprotein IIb/IIIa inhibitors across drugs and patient populations: a meta-analysis of 29 large placebo-controlled randomized trials. Eur Heart J Cardiovasc Pharmacother. 2015 Apr; 1(2):97-106. PMID: 27533978.
    View in: PubMed
  108. O'Donoghue ML, Ruff CT, Giugliano RP, Murphy SA, Grip LT, Mercuri MF, Rutman H, Shi M, Kania G, Cermak O, Braunwald E, Antman EM. Edoxaban vs. warfarin in vitamin K antagonist experienced and naive patients with atrial fibrillation†. Eur Heart J. 2015 Jun 14; 36(23):1470-7. PMID: 25687352.
    View in: PubMed
  109. Gonzalez Quesada CJ, Giugliano RP. Selecting an oral anticoagulant for patients with nonvalvular atrial fibrillation. J Thromb Thrombolysis. 2015 Jan; 39(1):129-38. PMID: 25416142.
    View in: PubMed
  110. Dogliotti A, Giugliano RP. A novel approach indirectly comparing benefit-risk balance across anti-thrombotic therapies in patients with atrial fibrillation. Eur Heart J Cardiovasc Pharmacother. 2015 Jan; 1(1):15-28. PMID: 27533960.
    View in: PubMed
  111. Sheth SD, Giugliano RP. Coronary artery stents: advances in technology. Hosp Pract (1995). 2014 Oct; 42(4):83-91. PMID: 25502132.
    View in: PubMed
  112. Ruff CT, Giugliano RP, Braunwald E, Mercuri M, Curt V, Betcher J, Grip L, Cange AL, Crompton AE, Murphy SA, Deenadayalu N, Antman EM. Transition of patients from blinded study drug to open-label anticoagulation: the ENGAGE AF-TIMI 48 trial. J Am Coll Cardiol. 2014 Aug 12; 64(6):576-84. PMID: 25104527.
    View in: PubMed
  113. Plitt A, Giugliano RP. Target-specific oral anticoagulants: practice issues for the clinician. Hosp Pract (1995). 2014 Aug; 42(3):48-61. PMID: 25255406.
    View in: PubMed
  114. Nicolau JC, Barbosa CJ, Franci A, Baracioli LM, Franken M, Lima FG, Giraldez RR, Kalil Filho R, Ramires JA, Giugliano RP. Do diabetic patients with acute coronary syndromes have a higher threshold for ischemic pain? Arq Bras Cardiol. 2014 Sep; 103(3):183-91. PMID: 25076180; PMCID: PMC4193065.
  115. Dasari TW, Roe MT, Chen AY, Peterson ED, Giugliano RP, Fonarow GC, Saucedo JF. Impact of time of presentation on process performance and outcomes in ST-segment-elevation myocardial infarction: a report from the American Heart Association: Mission Lifeline program. Circ Cardiovasc Qual Outcomes. 2014 Sep; 7(5):656-63. PMID: 25074371.
    View in: PubMed
  116. Giugliano RP. Once-daily edoxaban: a safer option than well-managed warfarin for patients with atrial fibrillation? Eur Heart J. 2014 Jul 21; 35(28):1826-7. PMID: 25184175.
    View in: PubMed
  117. Toleva O, Westerhout CM, Senaratne MP, Bode C, Lindroos M, Sulimov VA, Montalescot G, Newby LK, Giugliano RP, Van de Werf F, Armstrong PW. Practice patterns and clinical outcomes among non-ST-segment elevation acute coronary syndrome (NSTE-ACS) patients presenting to primary and tertiary hospitals: insights from the EARLY glycoprotein IIb/IIIa inhibition in NSTE-ACS (EARLY-ACS) trial. Catheter Cardiovasc Interv. 2014 Nov 15; 84(6):934-42. PMID: 24976083.
    View in: PubMed
  118. Ruff CT, Giugliano RP, Braunwald E, Antman EM. New oral anticoagulants in patients with atrial fibrillation - Authors'reply. Lancet. 2014 Jul 05; 384(9937):25-6. PMID: 24998809.
    View in: PubMed
  119. Giugliano RP, Ruff CT, Rost NS, Silverman S, Wiviott SD, Lowe C, Deenadayalu N, Murphy SA, Grip LT, Betcher JM, Duggal A, Dave J, Shi M, Mercuri M, Antman EM, Braunwald E. Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48. Stroke. 2014 Aug; 45(8):2372-8. PMID: 24947287.
    View in: PubMed
  120. Gonzalez-Quesada CJ, Giugliano RP. Erratum to: Comparison of the Phase III Clinical Trial Designs of Novel Oral Anticoagulants Versus Warfarin for the Treatment of Nonvalvular Atrial Fibrillation: Implications for Clinical Practice. Am J Cardiovasc Drugs. 2014 Jun; 14(3):237. PMID: 24777533.
    View in: PubMed
  121. Blazing MA, Giugliano RP, Cannon CP, Musliner TA, Tershakovec AM, White JA, Reist C, McCagg A, Braunwald E, Califf RM. Evaluating cardiovascular event reduction with ezetimibe as an adjunct to simvastatin in 18,144 patients after acute coronary syndromes: final baseline characteristics of the IMPROVE-IT study population. Am Heart J. 2014 Aug; 168(2):205-12.e1. PMID: 25066560.
    View in: PubMed
  122. Mehta RH, Westerhout CM, Zheng Y, Giugliano RP, Huber K, Prabhakaran D, Harrington RA, Newby KL, Armstrong PW. Association of metabolic syndrome and its individual components with outcomes among patients with high-risk non-ST-segment elevation acute coronary syndromes. Am Heart J. 2014 Aug; 168(2):182-8.e1. PMID: 25066557.
    View in: PubMed
  123. Mega JL, Giugliano RP. Genotype-guided dosing of warfarin. Clin Chem. 2014 Jul; 60(7):920-2. PMID: 24691686.
    View in: PubMed
  124. Gonzalez-Quesada CJ, Giugliano RP. Comparison of the phase III clinical trial designs of novel oral anticoagulants versus warfarin for the treatment of nonvalvular atrial fibrillation: implications for clinical practice. Am J Cardiovasc Drugs. 2014 Apr; 14(2):111-27. PMID: 24504768.
    View in: PubMed
  125. Reddy P, Giugliano RP. The role of rivaroxaban in atrial fibrillation and acute coronary syndromes. J Cardiovasc Pharmacol Ther. 2014 Nov; 19(6):526-32. PMID: 24659084.
    View in: PubMed
  126. Plitt A, Giugliano RP. Edoxaban: Review of pharmacology and key phase I to III clinical trials. J Cardiovasc Pharmacol Ther. 2014 Sep; 19(5):409-16. PMID: 24607764.
    View in: PubMed
  127. Stein EA, Giugliano RP, Koren MJ, Raal FJ, Roth EM, Weiss R, Sullivan D, Wasserman SM, Somaratne R, Kim JB, Yang J, Liu T, Albizem M, Scott R, Sabatine MS. Efficacy and safety of evolocumab (AMG 145), a fully human monoclonal antibody to PCSK9, in hyperlipidaemic patients on various background lipid therapies: pooled analysis of 1359 patients in four phase 2 trials. Eur Heart J. 2014 Sep 01; 35(33):2249-59. PMID: 24598985.
    View in: PubMed
  128. Plitt A, Giugliano RP. Edoxaban or standard therapy with warfarin for stroke prevention in patients with atrial fibrillation? Future Cardiol. 2014 Mar; 10(2):153-5. PMID: 24762238.
    View in: PubMed
  129. Raal FJ, Giugliano RP, Sabatine MS, Koren MJ, Langslet G, Bays H, Blom D, Eriksson M, Dent R, Wasserman SM, Huang F, Xue A, Albizem M, Scott R, Stein EA. Reduction in lipoprotein(a) with PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of more than 1,300 patients in 4 phase II trials. J Am Coll Cardiol. 2014 Apr 08; 63(13):1278-1288. PMID: 24509273.
    View in: PubMed
  130. Bergmark B, Giugliano RP. Perioperative management of target-specific oral anticoagulants. Hosp Pract (1995). 2014 Feb; 42(1):38-45. PMID: 24566595.
    View in: PubMed
  131. Kunadian V, Giugliano RP, Newby LK, Zorkun C, Guo J, Bagai A, Montalescot G, Braunwald E, Califf RM, Van de Werf F, Armstrong PW, Harrington R, Gibson CM. Angiographic outcomes with early eptifibatide therapy in non-ST-segment elevation acute coronary syndrome (from the EARLY ACS Trial). Am J Cardiol. 2014 Apr 15; 113(8):1297-305. PMID: 24607027.
    View in: PubMed
  132. Waks JW, Sabatine MS, Cannon CP, Morrow DA, Gibson CM, Wiviott SD, Giugliano RP, Sloan S, Scirica BM. Clinical implications and correlates of Q waves in patients with ST-elevation myocardial infarction treated with fibrinolysis: observations from the CLARITY-TIMI 28 trial. Clin Cardiol. 2014 Mar; 37(3):160-6. PMID: 24452727.
    View in: PubMed
  133. Ruff CT, Giugliano RP, Braunwald E, Hoffman EB, Deenadayalu N, Ezekowitz MD, Camm AJ, Weitz JI, Lewis BS, Parkhomenko A, Yamashita T, Antman EM. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2014 Mar 15; 383(9921):955-62. PMID: 24315724.
    View in: PubMed
  134. Gupta DK, Shah AM, Giugliano RP, Ruff CT, Antman EM, Grip LT, Deenadayalu N, Hoffman E, Patel I, Shi M, Mercuri M, Mitrovic V, Braunwald E, Solomon SD. Left atrial structure and function in atrial fibrillation: ENGAGE AF-TIMI 48. Eur Heart J. 2014 Jun 07; 35(22):1457-65. PMID: 24302269; PMCID: PMC4048534.
  135. Murphy SA, Giugliano RP. Atrial fibrillation and prior MI: searching for balance in ischaemic and bleeding events in patients treated with factor-specific anticoagulants. Eur Heart J. 2014 Jan; 35(4):207-8. PMID: 24282188.
    View in: PubMed
  136. Koren MJ, Giugliano RP, Raal FJ, Sullivan D, Bolognese M, Langslet G, Civeira F, Somaratne R, Nelson P, Liu T, Scott R, Wasserman SM, Sabatine MS. Efficacy and safety of longer-term administration of evolocumab (AMG 145) in patients with hypercholesterolemia: 52-week results from the Open-Label Study of Long-Term Evaluation Against LDL-C (OSLER) randomized trial. Circulation. 2014 Jan 14; 129(2):234-43. PMID: 24255061.
    View in: PubMed
  137. Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, Waldo AL, Ezekowitz MD, Weitz JI, Špinar J, Ruzyllo W, Ruda M, Koretsune Y, Betcher J, Shi M, Grip LT, Patel SP, Patel I, Hanyok JJ, Mercuri M, Antman EM. Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2013 Nov 28; 369(22):2093-104. PMID: 24251359.
    View in: PubMed
  138. Giugliano RP, Braunwald E. The year in acute coronary syndrome. J Am Coll Cardiol. 2014 Jan 28; 63(3):201-14. PMID: 24239661.
    View in: PubMed
  139. Desai NR, Giugliano RP, Zhou J, Kohli P, Somaratne R, Hoffman E, Liu T, Scott R, Wasserman SM, Sabatine MS. AMG 145, a monoclonal antibody against PCSK9, facilitates achievement of national cholesterol education program-adult treatment panel III low-density lipoprotein cholesterol goals among high-risk patients: an analysis from the LAPLACE-TIMI 57 trial (LDL-C assessment with PCSK9 monoclonal antibody inhibition combined with statin thErapy-thrombolysis in myocardial infarction 57). J Am Coll Cardiol. 2014 Feb 11; 63(5):430-3. PMID: 24161333.
    View in: PubMed
  140. Mogabgab O, Wiviott SD, Cannon CP, Sloan S, Sabatine MS, Antman EM, Braunwald E, Giugliano RP. Circadian variation of stent thrombosis and the effect of more robust platelet inhibition: a post hoc analysis of the TRITON-TIMI 38 trial. J Cardiovasc Pharmacol Ther. 2013 Nov; 18(6):555-9. PMID: 24064010.
    View in: PubMed
  141. Bohula May EA, Bonaca MP, Jarolim P, Antman EM, Braunwald E, Giugliano RP, Newby LK, Sabatine MS, Morrow DA. Prognostic performance of a high-sensitivity cardiac troponin I assay in patients with non-ST-elevation acute coronary syndrome. Clin Chem. 2014 Jan; 60(1):158-64. PMID: 24052087.
    View in: PubMed
  142. Dogliotti A, Paolasso E, Giugliano RP. Current and new oral antithrombotics in non-valvular atrial fibrillation: a network meta-analysis of 79 808 patients. Heart. 2014 Mar; 100(5):396-405. PMID: 24009224.
    View in: PubMed
  143. Kaul P, Tanguay JF, Newby LK, Hochman JS, Westerhout CM, Califf RM, Tricoci P, Gibson CM, Giugliano RP, Harrington RA, Van de Werf F, Armstrong PW. Association between bleeding and mortality among women and men with high-risk acute coronary syndromes: insights from the Early versus Delayed, Provisional Eptifibatide in Acute Coronary Syndromes (EARLY ACS) trial. Am Heart J. 2013 Oct; 166(4):723-8. PMID: 24093853.
    View in: PubMed
  144. Bergmark BA, Sobieszczyk P, Gravereaux EC, Bonaca M, Giugliano RP. Acute dissection of the descending aorta: a case report and review of the literature. Cardiol Ther. 2013 Dec; 2(2):199-213. PMID: 25135397; PMCID: PMC4107428.
  145. Bagai A, White JA, Lokhnygina Y, Giugliano RP, Van de Werf F, Montalescot G, Armstrong PW, Tricoci P, Gibson CM, Califf RM, Harrington RA, Newby LK. Routine early eptifibatide versus delayed provisional use at percutaneous coronary intervention in high-risk non-ST-segment elevation acute coronary syndromes patients: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome trial. Am Heart J. 2013 Sep; 166(3):466-73. PMID: 24016495.
    View in: PubMed
  146. Desai NR, Kohli P, Giugliano RP, O'Donoghue ML, Somaratne R, Zhou J, Hoffman EB, Huang F, Rogers WJ, Wasserman SM, Scott R, Sabatine MS. AMG145, a monoclonal antibody against proprotein convertase subtilisin kexin type 9, significantly reduces lipoprotein(a) in hypercholesterolemic patients receiving statin therapy: an analysis from the LDL-C Assessment with Proprotein Convertase Subtilisin Kexin Type 9 Monoclonal Antibody Inhibition Combined with Statin Therapy (LAPLACE)-Thrombolysis in Myocardial Infarction (TIMI) 57 trial. Circulation. 2013 Aug 27; 128(9):962-9. PMID: 23884353.
    View in: PubMed
  147. Shimada YJ, Giugliano RP. Emerging antithrombotic drugs for acute coronary syndrome. Expert Opin Emerg Drugs. 2013 Sep; 18(3):307-18. PMID: 23848430.
    View in: PubMed
  148. Plitt A, Dorbala S, Albert MA, Giugliano RP. Cardiac sarcoidosis: case report, workup, and review of the literature. Cardiol Ther. 2013 Dec; 2(2):181-97. PMID: 25135396; PMCID: PMC4107425.
  149. Sarma A, Rossi JE, Connors JM, Giugliano RP. Dabigatran excess: case report and review of the literature. Cardiol Ther. 2013 Jun; 2(1):111-24. PMID: 25135294; PMCID: PMC4107435.
  150. Nerini E, Grip L, Camm AJ, Giugliano RP. Atrial fibrillation and the 'other drug problem': reducing non-adherence with technology. Eur Heart J. 2013 Jul; 34(27):2031-3. PMID: 23704706.
    View in: PubMed
  151. Piccini JP, White JA, Mehta RH, Lokhnygina Y, Al-Khatib SM, Tricoci P, Califf RM, Harrington RA, Newby LK, Pollack CV, Montalescot G, Van de Werf F, Gibson CM, Giugliano RP. Response to letter regarding article, “sustained ventricular tachycardia and ventricular fibrillation complicating non–ST-segment elevation acute coronary syndromes”. Circulation. 2013 May 21; 127(20):e634. PMID: 23833786.
    View in: PubMed
  152. Tricoci P, Leonardi S, White J, White HD, Armstrong PW, Montalescot G, Giugliano RP, Gibson CM, Van de Werf F, Califf RM, Harrington RA, Braunwald E, Mahaffey KW, Newby LK. Cardiac troponin after percutaneous coronary intervention and 1-year mortality in non-ST-segment elevation acute coronary syndrome using systematic evaluation of biomarker trends. J Am Coll Cardiol. 2013 Jul 16; 62(3):242-251. PMID: 23684676.
    View in: PubMed
  153. De Ferrari GM, Fox KA, White JA, Giugliano RP, Tricoci P, Reynolds HR, Hochman JS, Gibson CM, Théroux P, Harrington RA, Van de Werf F, White HD, Califf RM, Newby LK. Outcomes among non-ST-segment elevation acute coronary syndromes patients with no angiographically obstructive coronary artery disease: observations from 37,101 patients. Eur Heart J Acute Cardiovasc Care. 2014 Mar; 3(1):37-45. PMID: 24562802; PMCID: PMC3932771.
  154. Kohli P, Giugliano RP. Low-density lipoprotein lowering in 2013 by nonstatin agents: the discovery and development of promising novel targeted therapies. J Cardiovasc Pharmacol Ther. 2013 May; 18(3):199-210. PMID: 23580658.
    View in: PubMed
  155. Lopes RD, White JA, Atar D, Keltai M, Kleiman NS, White HD, Widimsky P, Zeymer U, Giugliano RP, Tricoci P, Braunwald E, Bode C, Ohman EM, Armstrong PW, Newby LK. Incidence, treatment, and outcomes of atrial fibrillation complicating non-ST-segment elevation acute coronary syndromes. Int J Cardiol. 2013 Oct 03; 168(3):2510-7. PMID: 23578889.
    View in: PubMed
  156. Wessler JD, Grip LT, Mendell J, Giugliano RP. The P-glycoprotein transport system and cardiovascular drugs. J Am Coll Cardiol. 2013 Jun 25; 61(25):2495-502. PMID: 23563132.
    View in: PubMed
  157. Rose JJ, Newby LK, Broderick S, Chiswell K, Van de Werf F, Armstrong PW, Mahaffey KW, Harrington RA, Ohman EM, Giugliano RP, Goodman SG, White HD, Califf RM, Granger CB, Lopes RD. Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes. J Am Coll Cardiol. 2013 Apr 02; 61(13):1461-3. PMID: 23500249.
    View in: PubMed
  158. Mogabgab O, Wiviott SD, Antman EM, Foody JM, Wang TY, Sabatine MS, Cannon CP, Li S, Giugliano RP. Relation between time of symptom onset of ST-segment elevation myocardial infarction and patient baseline characteristics: from the National Cardiovascular Data Registry. Clin Cardiol. 2013 Apr; 36(4):222-7. PMID: 23520015.
    View in: PubMed
  159. Martínez G, Rigotti A, Acevedo M, Navarrete C, Rosales J, Giugliano RP, Corbalán R. Cholesterol levels and the association of statins with in-hospital mortality of myocardial infarction patients insights from a Chilean registry of myocardial infarction. Clin Cardiol. 2013 Jun; 36(6):305-11. PMID: 23494544.
    View in: PubMed
  160. Klutstein MW, Westerhout CM, Armstrong PW, Giugliano RP, Lewis BS, Gibson CM, Lutchmedial S, Widimsky P, Steg PG, Dalby A, Zeymer U, Van de Werf F, Harrington RA, Newby LK, Rao SV. Radial versus femoral access, bleeding and ischemic events in patients with non-ST-segment elevation acute coronary syndrome managed with an invasive strategy. Am Heart J. 2013 Apr; 165(4):583-590.e1. PMID: 23537976.
    View in: PubMed
  161. Chakrabarti AK, Feeney K, Abueg C, Brown DA, Czyz E, Tendera M, Janosi A, Giugliano RP, Kloner RA, Weaver WD, Bode C, Godlewski J, Merkely B, Gibson CM. Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction. Am Heart J. 2013 Apr; 165(4):509-514.e7. PMID: 23537966.
    View in: PubMed
  162. Ezekowitz JA, Bakal JA, Westerhout CM, Giugliano RP, White H, Keltai M, Prabhakaran D, Tricoci P, Van de Werf F, Califf RM, Newby LK, Armstrong PW. The relationship between meteorological conditions and index acute coronary events in a global clinical trial. Int J Cardiol. 2013 Oct 03; 168(3):2315-21. PMID: 23416014.
    View in: PubMed
  163. Giraldez RR, Clare RM, Lopes RD, Dalby AJ, Prabhakaran D, Brogan GX, Giugliano RP, James SK, Tanguay JF, Pollack CV, Harrington RA, Braunwald E, Newby LK. Prevalence and clinical outcomes of undiagnosed diabetes mellitus and prediabetes among patients with high-risk non-ST-segment elevation acute coronary syndrome. Am Heart J. 2013 Jun; 165(6):918-925.e2. PMID: 23708162.
    View in: PubMed
  164. Dogliotti A, Paolasso E, Giugliano RP. Novel oral anticoagulants in atrial fibrillation: a meta-analysis of large, randomized, controlled trials vs warfarin. Clin Cardiol. 2013 Feb; 36(2):61-7. PMID: 23338902.
    View in: PubMed
  165. Hochholzer W, Giugliano RP. Does it make sense to combine statins with other lipid-altering agents following AIM-HIGH, SHARP and ACCORD? Curr Atheroscler Rep. 2013 Jan; 15(1):290. PMID: 23242605.
    View in: PubMed
  166. Tam LM, Fonarow GC, Bhatt DL, Grau-Sepulveda MV, Hernandez AF, Peterson ED, Schwamm LH, Giugliano RP. Achievement of guideline-concordant care and in-hospital outcomes in patients with coronary artery disease in teaching and nonteaching hospitals: results from the Get With The Guidelines-Coronary Artery Disease program. Circ Cardiovasc Qual Outcomes. 2013 Jan 01; 6(1):58-65. PMID: 23233750.
    View in: PubMed
  167. Giugliano RP. Letter from the editor. Cardiol Ther. 2012 Dec; 1(1):1. PMID: 25135155; PMCID: PMC4107446.
  168. Mogabgab O, Giugliano RP, Sabatine MS, Cannon CP, Mohanavelu S, Wiviott SD, Antman EM, Braunwald E. Circadian variation in patient characteristics and outcomes in ST-segment elevation myocardial infarction. Chronobiol Int. 2012 Dec; 29(10):1390-6. PMID: 23131034.
    View in: PubMed
  169. Giugliano RP, Desai NR, Kohli P, Rogers WJ, Somaratne R, Huang F, Liu T, Mohanavelu S, Hoffman EB, McDonald ST, Abrahamsen TE, Wasserman SM, Scott R, Sabatine MS. Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): a randomised, placebo-controlled, dose-ranging, phase 2 study. Lancet. 2012 Dec 08; 380(9858):2007-17. PMID: 23141813; PMCID: PMC4347805.
  170. Leonardi S, Thomas L, Neely ML, Tricoci P, Lopes RD, White HD, Armstrong PW, Giugliano RP, Antman EM, Califf RM, Newby LK, Mahaffey KW. Comparison of the prognosis of spontaneous and percutaneous coronary intervention-related myocardial infarction. J Am Coll Cardiol. 2012 Dec 04; 60(22):2296-304. PMID: 23122801.
    View in: PubMed
  171. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2012 Nov 20; 60(21):2127-39. PMID: 23103037.
    View in: PubMed
  172. Grip LT, Giugliano RP. Importance of dose selection in novel oral anticoagulants for atrial fibrillation. Arch Cardiol Mex. 2012 Oct-Dec; 82(4):308-11. PMID: 23168295.
    View in: PubMed
  173. Pride YB, Mohanavelu S, Zorkun C, Kunadian V, Giugliano RP, Newby LK, Braunwald E, Califf RM, Harrington RA, Gibson CM. Association between angiographic complications and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention: an EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) angiographic substudy. JACC Cardiovasc Interv. 2012 Sep; 5(9):927-35. PMID: 22995880.
    View in: PubMed
  174. Lopes RD, White JA, Tricoci P, White HD, Armstrong PW, Braunwald E, Giugliano RP, Harrington RA, Lewis BS, Brogan GX, Gibson CM, Califf RM, Newby LK. Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: insights from the EARLY ACS trial. Int J Cardiol. 2013 Sep 10; 167(6):2580-7. PMID: 22795720.
    View in: PubMed
  175. Kohli P, Desai NR, Giugliano RP, Kim JB, Somaratne R, Huang F, Knusel B, McDonald S, Abrahamsen T, Wasserman SM, Scott R, Sabatine MS. Design and rationale of the LAPLACE-TIMI 57 trial: a phase II, double-blind, placebo-controlled study of the efficacy and tolerability of a monoclonal antibody inhibitor of PCSK9 in subjects with hypercholesterolemia on background statin therapy. Clin Cardiol. 2012; 35(7):385-91. PMID: 22714699; PMCID: PMC4347804.
  176. Thomas D, Giugliano RP. Management of non-ST-segment elevation acute coronary syndrome: comparison of the updated guidelines from North America and Europe. Crit Pathw Cardiol. 2012 Jun; 11(2):62-73. PMID: 22595816.
    View in: PubMed
  177. Piccini JP, White JA, Mehta RH, Lokhnygina Y, Al-Khatib SM, Tricoci P, Pollack CV, Montalescot G, Van de Werf F, Gibson CM, Giugliano RP, Califf RM, Harrington RA, Newby LK. Sustained ventricular tachycardia and ventricular fibrillation complicating non-ST-segment-elevation acute coronary syndromes. Circulation. 2012 Jul 03; 126(1):41-9. PMID: 22645292.
    View in: PubMed
  178. Giugliano RP. Relationships among race, bleeding, and mortality in coronary reperfusion. Circulation. 2012 Apr 10; 125(14):1715-7. PMID: 22419698.
    View in: PubMed
  179. Salazar DE, Mendell J, Kastrissios H, Green M, Carrothers TJ, Song S, Patel I, Bocanegra TS, Antman EM, Giugliano RP, Kunitada S, Dornseif B, Shi M, Tachibana M, Zhou S, Rohatagi S. Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation. Thromb Haemost. 2012 May; 107(5):925-36. PMID: 22398655.
    View in: PubMed
  180. Roe MT, White JA, Kaul P, Tricoci P, Lokhnygina Y, Miller CD, van't Hof AW, Montalescot G, James SK, Saucedo J, Ohman EM, Pollack CV, Hochman JS, Armstrong PW, Giugliano RP, Harrington RA, Van de Werf F, Califf RM, Newby LK. Regional patterns of use of a medical management strategy for patients with non-ST-segment elevation acute coronary syndromes: insights from the EARLY ACS Trial. Circ Cardiovasc Qual Outcomes. 2012 Mar 01; 5(2):205-13. PMID: 22373905.
    View in: PubMed
  181. Chan MY, Sun JL, Newby LK, Lokhnygina Y, White HD, Moliterno DJ, Théroux P, Ohman EM, Simoons ML, Mahaffey KW, Pieper KS, Giugliano RP, Armstrong PW, Califf RM, Van de Werf F, Harrington RA. Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years. Int J Cardiol. 2013 Jul 31; 167(2):548-54. PMID: 22341697.
    View in: PubMed
  182. Desai NR, Giugliano RP. Can we predict outcomes in atrial fibrillation? Clin Cardiol. 2012 Jan; 35 Suppl 1:10-4. PMID: 22246946.
    View in: PubMed
  183. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2011 Nov 22; 58(22):2342-54. PMID: 22093514.
    View in: PubMed
  184. Giugliano RP. Niacin at 56 years of age--time for an early retirement? N Engl J Med. 2011 Dec 15; 365(24):2318-20. PMID: 22085318.
    View in: PubMed
  185. Melloni C, James SK, White JA, Giugliano RP, Harrington RA, Huber K, Tricoci P, Armstrong PW, Van de Werf F, Montalescot G, Califf RM, Newby LK. Safety and efficacy of adjusted-dose eptifibatide in patients with acute coronary syndromes and reduced renal function. Am Heart J. 2011 Nov; 162(5):884-892.e1. PMID: 22093205.
    View in: PubMed
  186. Nicolau JC, Serrano CV, Giraldez RR, Baracioli LM, Moreira HG, Lima F, Franken M, Kalil R, Ramires JA, Giugliano RP. In patients with acute myocardial infarction, the impact of hyperglycemia as a risk factor for mortality is not homogeneous across age-groups. Diabetes Care. 2012 Jan; 35(1):150-2. PMID: 22028280; PMCID: PMC3241319.
  187. Wessler JD, Saldana F, Giugliano RP. Bridging therapy after recent stent implantation: case report and review of data. Cardiovasc Revasc Med. 2012 Jan-Feb; 13(1):30-8. PMID: 22019210.
    View in: PubMed
  188. Del Río-Santiago V, Santiago-Trinidad R, Espinell-González N, Valentín-Nieves J, Giugliano RP, Rodriguez-Ospina L, Vicenty-Rivera S. Prevalence of anemia in a Hispanic population with decompensated congestive heart failure. Bol Asoc Med P R. 2011 Oct-Dec; 103(4):28-33. PMID: 22737827.
    View in: PubMed
  189. Silletta MG, Scarano M, Pioggiarella R, D'Ingianna AP, Giugliano R, Ruo M, Marchioli R. [Lifestyle, health and cardiovascular risk: the results of the study "Rischio & Prevenzione"]. Assist Inferm Ric. 2011 Oct-Dec; 30(4):198-207. PMID: 22322435.
    View in: PubMed
  190. Hochholzer W, Berg DD, Giugliano RP. The facts behind niacin. Ther Adv Cardiovasc Dis. 2011 Oct; 5(5):227-40. PMID: 21893559.
    View in: PubMed
  191. Reddy P, Atay JK, Selbovitz LG, Connors JM, Piazza G, Block CC, Arpino PA, Berliner N, Hutter AM, Fischer MA, Kuter D, Weitzman J, Sherwood GK, Almozlino A, Giugliano RP. Dabigatran: a review of clinical and pharmacoeconomic evidence. Crit Pathw Cardiol. 2011 Sep; 10(3):117-27. PMID: 21989032.
    View in: PubMed
  192. Partida RA, Giugliano RP. Edoxaban: pharmacological principles, preclinical and early-phase clinical testing. Future Cardiol. 2011 Jul; 7(4):459-70. PMID: 21797743.
    View in: PubMed
  193. Tricoci P, Newby LK, Hasselblad V, Kong DF, Giugliano RP, White HD, Théroux P, Stone GW, Moliterno DJ, Van de Werf F, Armstrong PW, Prabhakaran D, Rasoul S, Bolognese L, Durand E, Braunwald E, Califf RM, Harrington RA. Upstream use of small-molecule glycoprotein iib/iiia inhibitors in patients with non-ST-segment elevation acute coronary syndromes: a systematic overview of randomized clinical trials. Circ Cardiovasc Qual Outcomes. 2011 Jul; 4(4):448-58. PMID: 21712522.
    View in: PubMed
  194. Ehle M, Patel C, Giugliano RP. Digoxin: clinical highlights: a review of digoxin and its use in contemporary medicine. Crit Pathw Cardiol. 2011 Jun; 10(2):93-8. PMID: 21988950.
    View in: PubMed
  195. Hochholzer W, Wiviott SD, Antman EM, Contant CF, Guo J, Giugliano RP, Dalby AJ, Montalescot G, Braunwald E. Predictors of bleeding and time dependence of association of bleeding with mortality: insights from the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel--Thrombolysis in Myocardial Infarction 38 (TRITON-TIMI 38). Circulation. 2011 Jun 14; 123(23):2681-9. PMID: 21606391.
    View in: PubMed
  196. Kim SJ, Giugliano RP, Jang IK. Adjunctive pharmacologic therapy in percutaneous coronary intervention: part II anticoagulant therapy. Coron Artery Dis. 2011 Mar; 22(1):113-21. PMID: 21304293.
    View in: PubMed
  197. Kim SJ, Giugliano RP, Jang IK. Adjunctive pharmacologic therapy in percutaneous coronary intervention: part I antiplatelet therapy. Coron Artery Dis. 2011 Mar; 22(1):100-12. PMID: 20926950.
    View in: PubMed
  198. Wang TY, White JA, Tricoci P, Giugliano RP, Zeymer U, Harrington RA, Montalescot G, James SK, Van de Werf F, Armstrong PW, Braunwald E, Califf RM, Newby LK. Upstream clopidogrel use and the efficacy and safety of early eptifibatide treatment in patients with acute coronary syndrome: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) trial. Circulation. 2011 Feb 22; 123(7):722-30. PMID: 21300952.
    View in: PubMed
  199. Baron SJ, Giugliano RP. Effectiveness and safety of percutaneous coronary intervention after fibrinolytic therapy for ST-segment elevation acute myocardial infarction. Am J Cardiol. 2011 Apr 01; 107(7):1001-9. PMID: 21256466.
    View in: PubMed
  200. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2010 Dec 14; 56(25):2126-38. PMID: 21144974.
    View in: PubMed
  201. Giugliano RP, Pollack CV, Brogan GX, Cohen M, Diercks DB, Grines CL, Henry TD, Kleiman NS. Acute coronary syndromes: from the emergency department to the catheterization laboratory-integrating evidence from recent ACS/NSTEMI trials into clinical practice: an evidence-based review of recent clinical trial results and report on a roundtable discussion. J Interv Cardiol. 2011 Apr; 24(2):119-36. PMID: 21114529.
    View in: PubMed
  202. Ruff CT, Giugliano RP, Antman EM, Murphy SA, Lotan C, Heuer H, Merkely B, Baracioli L, Schersten F, Seabro-Gomes R, Braunwald E, Wiviott SD. Safety and efficacy of prasugrel compared with clopidogrel in different regions of the world. Int J Cardiol. 2012 Mar 22; 155(3):424-9. PMID: 21093072.
    View in: PubMed
  203. Iafusco D, Scaramuzza AE, Galderisi A, Cocca A, Giugliano R, Zuccotti GV, Prisco F. Not every child with diabetes needs insulin. BMJ. 2010 Nov 16; 341:c6512. PMID: 21081621.
    View in: PubMed
  204. Pollack CV, Brogan GX, Cohen M, Diercks D, Grines C, Henry TD, Kleiman NS, Giugliano RP. ED to catheterization laboratory: a roundtable integrating trials with practice. Am J Emerg Med. 2011 Nov; 29(9):1203-16. PMID: 20971595.
    View in: PubMed
  205. Rich JD, Cannon CP, Murphy SA, Qin J, Giugliano RP, Braunwald E. Prior aspirin use and outcomes in acute coronary syndromes. J Am Coll Cardiol. 2010 Oct 19; 56(17):1376-85. PMID: 20946994.
    View in: PubMed
  206. Hochholzer W, Morrow DA, Giugliano RP. Novel biomarkers in cardiovascular disease: update 2010. Am Heart J. 2010 Oct; 160(4):583-94. PMID: 20934551.
    View in: PubMed
  207. Ruff CT, Giugliano RP, Antman EM, Crugnale SE, Bocanegra T, Mercuri M, Hanyok J, Patel I, Shi M, Salazar D, McCabe CH, Braunwald E. Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF-TIMI 48). Am Heart J. 2010 Oct; 160(4):635-41. PMID: 20934556.
    View in: PubMed
  208. Thomas D, Giugliano RP. Perspectives on the 2009 focused updates on the management of ST-segment elevation myocardial infarction and percutaneous intervention. Crit Pathw Cardiol. 2010 Sep; 9(3):126-33. PMID: 20802265.
    View in: PubMed
  209. Pride YB, Tung P, Mohanavelu S, Zorkun C, Wiviott SD, Antman EM, Giugliano R, Braunwald E, Gibson CM. Angiographic and clinical outcomes among patients with acute coronary syndromes presenting with isolated anterior ST-segment depression: a TRITON-TIMI 38 (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolysis In Myocardial Infarction 38) substudy. JACC Cardiovasc Interv. 2010 Aug; 3(8):806-11. PMID: 20723851.
    View in: PubMed
  210. Kaul S, Bolger AF, Herrington D, Giugliano RP, Eckel RH. Thiazolidinedione drugs and cardiovascular risks: a science advisory from the American Heart Association and American College Of Cardiology Foundation. J Am Coll Cardiol. 2010 Apr 27; 55(17):1885-94. PMID: 20413044.
    View in: PubMed
  211. Giugliano RP, Giraldez RR, Morrow DA, Antman EM, Gibson CM, Mohanavelu S, Murphy SA, McCabe CH, Braunwald E. Relations between bleeding and outcomes in patients with ST-elevation myocardial infarction in the ExTRACT-TIMI 25 trial. Eur Heart J. 2010 Sep; 31(17):2103-10. PMID: 20413397.
    View in: PubMed
  212. Morrow DA, Antman EM, Fox KA, White HD, Giugliano R, Murphy SA, McCabe CH, Braunwald E. One-year outcomes after a strategy using enoxaparin vs. unfractionated heparin in patients undergoing fibrinolysis for ST-segment elevation myocardial infarction: 1-year results of the ExTRACT-TIMI 25 trial. Eur Heart J. 2010 Sep; 31(17):2097-102. PMID: 20400762.
    View in: PubMed
  213. Hochholzer W, Giugliano RP. Lipid lowering goals: back to nature? Ther Adv Cardiovasc Dis. 2010 Jun; 4(3):185-91. PMID: 20400493.
    View in: PubMed
  214. Califf RM, Lokhnygina Y, Cannon CP, Stepanavage ME, McCabe CH, Musliner TA, Pasternak RC, Blazing MA, Giugliano RP, Harrington RA, Braunwald E. An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design. Am Heart J. 2010 May; 159(5):705-9. PMID: 20435175.
    View in: PubMed
  215. Kaul S, Bolger AF, Herrington D, Giugliano RP, Eckel RH. Thiazolidinedione drugs and cardiovascular risks: a science advisory from the American Heart Association and American College of Cardiology Foundation. Circulation. 2010 Apr 27; 121(16):1868-77. PMID: 20179252.
    View in: PubMed
  216. Harkness JR, Sabatine MS, Braunwald E, Morrow DA, Sloan S, Wiviott SD, Giugliano RP, Antman EM, Cannon CP, Scirica BM. Extent of ST-segment resolution after fibrinolysis adds improved risk stratification to clinical risk score for ST-segment elevation myocardial infarction. Am Heart J. 2010 Jan; 159(1):55-62. PMID: 20102867.
    View in: PubMed
  217. Bonaca M, Giugliano RP. Antithrombotics in acute coronary syndromes: updates from the past year. Curr Treat Options Cardiovasc Med. 2010 Jan; 12(1):84-99. PMID: 20842484.
    View in: PubMed
  218. Thomas D, Giugliano RP. Day 1 care in patients with non-ST-segment elevation myocardial infarction. Cardiovasc Revasc Med. 2010 Jan-Mar; 11(1):41-51. PMID: 20129360.
    View in: PubMed
  219. Huynh T, Nasmith J, Luong TM, Bernier M, Pharand C, Xue-Qiao Z, Giugliano RP, Theroux P. Complementary prognostic values of ST segment deviation and Thrombolysis In Myocardial Infarction (TIMI) risk score in non-ST elevation acute coronary syndromes: Insights from the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) study. Can J Cardiol. 2009 Dec; 25(12):e417-21. PMID: 19960136; PMCID: PMC2807838.
  220. Thomas D, Giugliano RP. Management of ST-segment elevation myocardial infarction: Comparison of the updated guidelines from North America and Europe. Am Heart J. 2009 Nov; 158(5):695-705. PMID: 19853685.
    View in: PubMed
  221. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2009 Oct 13; 54(16):1544-55. PMID: 19815127.
    View in: PubMed
  222. Bonaca MP, Steg PG, Feldman LJ, Canales JF, Ferguson JJ, Wallentin L, Califf RM, Harrington RA, Giugliano RP. Antithrombotics in acute coronary syndromes. J Am Coll Cardiol. 2009 Sep 08; 54(11):969-84. PMID: 19729112.
    View in: PubMed
  223. Giraldez RR, Wiviott SD, Nicolau JC, Mohanavelu S, Morrow DA, Antman EM, Giugliano RP. Streptokinase and enoxaparin as an alternative to fibrin-specific lytic-based regimens: an ExTRACT-TIMI 25 analysis. Drugs. 2009 Jul 30; 69(11):1433-43. PMID: 19634922.
    View in: PubMed
  224. Giugliano RP, White JA, Bode C, Armstrong PW, Montalescot G, Lewis BS, van 't Hof A, Berdan LG, Lee KL, Strony JT, Hildemann S, Veltri E, Van de Werf F, Braunwald E, Harrington RA, Califf RM, Newby LK. Early versus delayed, provisional eptifibatide in acute coronary syndromes. N Engl J Med. 2009 May 21; 360(21):2176-90. PMID: 19332455.
    View in: PubMed
  225. Desai NR, Cheng S, Nohria A, Halperin F, Giugliano RP. Clinical problem-solving. When past is prologue. N Engl J Med. 2009 Mar 05; 360(10):1016-22. PMID: 19264691.
    View in: PubMed
  226. Thomas D, Giugliano RP. Antiplatelet therapy in percutaneous coronary intervention: integration of prasugrel into clinical practice. Crit Pathw Cardiol. 2009 Mar; 8(1):12-9. PMID: 19258833.
    View in: PubMed
  227. Truong QA, Cannon CP, Zakai NA, Rogers IS, Giugliano RP, Wiviott SD, McCabe CH, Morrow DA, Braunwald E. Thrombolysis in Myocardial Infarction (TIMI) Risk Index predicts long-term mortality and heart failure in patients with ST-elevation myocardial infarction in the TIMI 2 clinical trial. Am Heart J. 2009 Apr; 157(4):673-9.e1. PMID: 19332194; PMCID: PMC2694948.
  228. Saab F, Giugliano RP, Giugliano GR. Takayasu arteritis in a young woman: a 4-year case history. Tex Heart Inst J. 2009; 36(5):470-4. PMID: 19876432; PMCID: PMC2763464.
  229. Di Bonito P, De Natale C, Salvatore T, Vaccaro O, Armentano V, Adinolfi D, Giugliano R, Capaldo B. Management of type 2 diabetic patients attending diabetic outpatient clinics compared with those cared for by the general practitioners: an experience of integrated diabetes management. Ann Ist Super Sanita. 2009; 45(2):162-7. PMID: 19636167.
    View in: PubMed
  230. Thao H, Nasmith J, Luong TM, Bernier M, Pharand C, Xue-Qioa Z, Giugliano RP, Theroux P. Complementary prognostic values of ST segment deviation and TIMI risk score in Non-ST-Elevation Acute Coronary Syndromes: Insights from the PRISM-PLUS study. Canadian Journal of Cardiology for 2009, "In Press". 2009.
  231. Thomas, D., Giugliano, RP. Antiplatelet Therapy in Percutaneous Coronary Intervention: Integration of Prasugrel into Clinical Practice. Critical Pathways in Cardiology, "In Press". 2009.
  232. Thomas D, Giugliano RP. ExTRACT-TIMI 25 in perspective: key lessons regarding enoxaparin as an adjunct to fibrinolytic therapy. J Thromb Thrombolysis. 2009 Jan; 27(1):1-10. PMID: 18931978.
    View in: PubMed
  233. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2008 Sep 23; 52(13):1095-103. PMID: 18848144.
    View in: PubMed
  234. Giraldez RR, Giugliano RP, Mohanavelu S, Murphy SA, McCabe CH, Cannon CP, Braunwald E. Baseline low-density lipoprotein cholesterol is an important predictor of the benefit of intensive lipid-lowering therapy: a PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) analysis. J Am Coll Cardiol. 2008 Sep 09; 52(11):914-20. PMID: 18772061.
    View in: PubMed
  235. Cannon CP, Giugliano RP, Blazing MA, Harrington RA, Peterson JL, Sisk CM, Strony J, Musliner TA, McCabe CH, Veltri E, Braunwald E, Califf RM. Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes. Am Heart J. 2008 Nov; 156(5):826-32. PMID: 19061694.
    View in: PubMed
  236. Cohen M, Hoekstra J, Giugliano R, Granger CB, Gurbel PA, Hollander JE, Manoukian SV, Pollack CV, Saucedo JF. Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion. J Interv Cardiol. 2008 Aug; 21(4):283-99. PMID: 18754964.
    View in: PubMed
  237. Thomas D, Giugliano RP. Antiplatelet therapy in early management of non-ST-segment elevation acute coronary syndrome: the 2002 and 2007 guidelines from North America and Europe. J Cardiovasc Pharmacol. 2008 May; 51(5):425-33. PMID: 18418272.
    View in: PubMed
  238. Harkness JR, Scirica BM, Sabatine MS, Morrow DA, Sloan S, Wiviott SD, Giugliano RP, Cannon CP, Braunwald E. Extent of ST Segment Resolution After Fibrinolysis Adds Dynamic Risk Stratification to the TIMI Risk Score for STEMI. J Am Coll Cardiol. 2008; 51(10):A221.
  239. Giugliano RP, Giraldez RR, Morrow DA, Antman EM, Gibson CM, Mohanavelu S, Murphy SA, McCabe CH, Braunwald E. The Relative Contribution of Clinical Factors, Treatments, Bleding, and CV Complications to Mortality in 20,323 Patietns Receiving Fibrinolysis for STEMI. J Am Coll Cardiol. 2008; 51(10):A209.
  240. Ahmed S, Cannon CP, Giugliano RP, Murphy SA, Morrow DA, Antman EM, Braunwald E, Gibson CM. The independent and combined risk of diabetes and non-endstage renal impairment in non-ST-segment elevation acute coronary syndromes. Int J Cardiol. 2008 Dec 17; 131(1):105-12. PMID: 18187215.
    View in: PubMed
  241. Lefebvre CW, Hoekstra JW, Bonaca M, Giugliano R. Glycoprotein IIb-IIIa inhibitors in the Emergency Department for patients with non-ST-elevation acute coronary syndromes: Principles and practices. J Emer Med. 2008; (In press).
  242. Giugliano RP. Design Issues in Clinical Trials of Thrombolytic and Antithrombotic Agents. New Therapeutic Agents in Thrombolysis, Freedman J, Loscalzo J. editors "In Press". 2008.
  243. Giraldez RR, Giugliano RP. . Current Perspectives in Anticoagulant Therapy for Non-ST-Segment Elevation Acute Coronary Syndromes. In: "In Press". 2008.
  244. Kashani A, Giugliano RP. Management of ST-elevation myocardial infarction: an update on pharmacoinvasive recanalization. Am J Cardiovasc Drugs. 2008; 8(3):187-97. PMID: 18533739.
    View in: PubMed
  245. Giraldez RR, Giugliano RP, Mohanavelu S, Murphy SA, McCabe CH, Cannon CP, Braunwald E. Baseline Low-Density Lipoprotein Chlesterol Is an Important Predictor of the Benefit of Intensive Lipid-Lowering Therapy. JACC. 2008; 52:914-20.
  246. Giraldez RR, Wiviott SD, Giugliano RP, Nicolau JC, Mohanavelu S, Morrow DA, Antman EM, Braunwald E. Fibrinolytic Therapy with Streptokinase and Enoxaparin is Associated with Improved Outcomes Compared to Fibrin-specific Lytics and Unfractionated Heparin - an ExTRACT-TIMI 25 Analysis. European Heart Journal, "In Press". 2008.
  247. Kashani A, Giugliano RP. Management of ST-Elevation Myocardial Infarction An Update on Pharmacoinvasive Recanalization. American Journal Cardiovascular Drugs. 2008; 8(3):1-11.
  248. Giraldez RR, Giugliano RP, Qin J, Buros J, McCabe CH, Morrow DA, Antman EM, Braunwald E. Gross National Income Per Person Accounts for Global Differences in Mortality Rates in STEMI Patients Undergoing Fibrinoysis - ExTRACT-TIMI 25 Analysis. European Heart Journal "In Press". 2008.
  249. Forman DE, Giugliano RP, Cannon CP, Morrow DA, Qin J, Antman EM, Braunwald E. A Simple TIMI Discharge Risk Score Post ACS Predicts CV Mortality at 2 Years. Circulation, "In Press". 2008.
  250. Kashani A, Giugliano RP. Facilitated Primary PCI in Acute ST-Elevation Myocardial Infarction. Walkers R, editor. "In Press". 2008.
  251. Mousa SA, Willerson JT, Giugliano RP. Overview of Antiplatelet Therapy. New Therapeutic Agents in Thrombolysis, Freedman J, Loscalzo J. editors, "In Press". 2008.
  252. Yeh RW, Wiviott SD, Giugliano RP, Morrow DA, Shui A, Qin J, Scirica B, Bradner JE, Jang IK, Gibson CM, Antman EM. Effect of thrombocytopenia on outcomes following treatment with either enoxaparin or unfractionated heparin in patients presenting with acute coronary syndromes. Am J Cardiol. 2007 Dec 15; 100(12):1734-8. PMID: 18082517.
    View in: PubMed
  253. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2007 Oct 02; 50(14):1386-95. PMID: 17903640.
    View in: PubMed
  254. Fluture A, Giugliano GR, Giugliano RP. Recombinant nematode anticoagulant protein c2 in non-ST segment elevation acute coronary syndrome and beyond. Future Cardiol. 2007 Jul; 3(4):365-75. PMID: 19804227.
    View in: PubMed
  255. Scirica BM, Morrow DA, Sadowski Z, Ruda M, Nicolau JC, Giugliano RP, Wiviott SD, Sabatine MS, Shui A, Antman EM, Braunwald E. A strategy of using enoxaparin as adjunctive antithrombin therapy reduces death and recurrent myocardial infarction in patients who achieve early ST-segment resolution after fibrinolytic therapy: the ExTRACT-TIMI 25 ECG study. Eur Heart J. 2007 Sep; 28(17):2070-6. PMID: 17600039.
    View in: PubMed
  256. Giugliano RP, Wiviott SD, Stone PH, Simon DI, Schweiger MJ, Bouchard A, Leesar MA, Goulder MA, Deitcher SR, McCabe CH, Braunwald E. Recombinant nematode anticoagulant protein c2 in patients with non-ST-segment elevation acute coronary syndrome: the ANTHEM-TIMI-32 trial. J Am Coll Cardiol. 2007 Jun 26; 49(25):2398-407. PMID: 17599602.
    View in: PubMed
  257. Bach RG, Giugliano RP, Simon DI, Schweiger MJ, Leesar MA, Wiviott SD, Goulder MA, Deitcher SR, Braunwald E. Safety and tolerability of a novel tissue factor/factor VIIa inhibitor rNAPc2 in patients with non-ST elevation acute coronary syndrome managed invasively: Results from the ANTHEM-TIMI 32 Trial. J Am Coll Cardiol. 2007; 49(9 (Suppl A)):196A.
  258. Dorbala S, Giugliano RP, Logsetty G, Vangala D, Mishra R, Crugnale S, Yang D, Di Carli MF. Prognostic value of SPECT myocardial perfusion imaging in patients with elevated cardiac troponin I levels and atypical clinical presentation. J Nucl Cardiol. 2007 Jan; 14(1):53-8. PMID: 17276306.
    View in: PubMed
  259. Ruff CT, Morrow DA, Giugliano RP. Tissue FActor Inhibitors. In: Clinical Guide to the Use of Antithrombotic Drugs in Coronary Artery Disease. Ed Angiolilo DJ, Kastrati A, Simon DI editors. London Informa UK Ltd. 2007.
  260. Giugliano RP. MD Conference Express. 2007.
  261. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndromes. J Am Coll Cardiol. 2006 Jul 18; 48(2):386-95. PMID: 16843191.
    View in: PubMed
  262. Scirica BM, Sabatine MS, Morrow DA, Gibson CM, Murphy SA, Wiviott SD, Giugliano RP, McCabe CH, Cannon CP, Braunwald E. The role of clopidogrel in early and sustained arterial patency after fibrinolysis for ST-segment elevation myocardial infarction: the ECG CLARITY-TIMI 28 Study. J Am Coll Cardiol. 2006 Jul 04; 48(1):37-42. PMID: 16814646.
    View in: PubMed
  263. Allen LA, O'Donnell CJ, Camargo CA, Giugliano RP, Lloyd-Jones DM. Comparison of long-term mortality across the spectrum of acute coronary syndromes. Am Heart J. 2006 May; 151(5):1065-71. PMID: 16644337.
    View in: PubMed
  264. Dumaine R, Gibson CM, Murphy SA, Southard M, Ly HQ, McCabe CH, Giugliano RP, Cannon CP, Antman EM, Braunwald E. Association of a history of systemic hypertension with mortality, thrombotic, and bleeding complications following non-ST-segment elevation acute coronary syndrome. J Clin Hypertens (Greenwich). 2006 May; 8(5):315-22. PMID: 16687939.
    View in: PubMed
  265. Ahmed S, Antman EM, Murphy SA, Giugliano RP, Cannon CP, White H, Morrow DA, Braunwald E. Poor outcomes after fibrinolytic therapy for ST-segment elevation myocardial infarction: impact of age (a meta-analysis of a decade of trials). J Thromb Thrombolysis. 2006 Apr; 21(2):119-29. PMID: 16622607.
    View in: PubMed
  266. Ruff CT, Giugliano R, Morrow DA. Inhibition of tissue factor as a novel approach to anticoagulation in patients with coronary artery disease. Future Cardiol. 2006 Jan; 2(1):85-91. PMID: 19804135.
    View in: PubMed
  267. Wiviott SD, Stone PH, Bouchard A, Alshaher M, Goulder M, Deitcher SR, Giugliano RP. F1.2 Correlates with Ischemia by Holter Monitoring and is Suppressed by rNAPc2: An ANTHEM-TIMI 32 Biomarker Analysis. AHA. 2006.
  268. Fluture A, Giugliano GR, Southard MC, Schweiger MJ, Gibson CM, Buros J, Goulder M, Deitcher S, Giugliano RP. Angiographic Outcomes in Patients with Non-STE ACS Undergoing PCI Using Adjunctive Recombinant Nematode Anticoagulant Protein c2 Versus Placebo: An ANTHEM-TIMI 32 Anngiographic Core Lab Analysis. TCT. 2006.
  269. Wiviott SD, Giugliano RP. Non-ST-elevation acute coronary syndromes. Antman EM, editor. Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease. 2006.
  270. Narula T, Southard MC, Gibson CM, Bouchard A, Singh VN, Goulder M, Deitcher SR, Giugliano RP. Outcomes in Patients with NSTE-ACS Undergoing PCI on a Novel Tissue Factor/factor VIIa Inhibitor (rNAPc2) with Full, Half-Dose or No Heparin in the ANTHEM-TIMI 32 Trial. TCT. 2006.
  271. Giugliano RP. MD Conference Express. 2006.
  272. Giraldez RR, Antman EM, Giugliano RP. The challenge of treating ST-segment elevation myocardial infarction in the elderly. Bhatt DL, Merli GJ, editors. Thrombosis Clinic. 2006; 27-41.
  273. Ilkhanoff L, O'Donnell CJ, Camargo CA, O'Halloran TD, Giugliano RP, Lloyd-Jones DM. Usefulness of the TIMI Risk Index in predicting short- and long-term mortality in patients with acute coronary syndromes. Am J Cardiol. 2005 Sep 15; 96(6):773-7. PMID: 16169358.
    View in: PubMed
  274. Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndromes. J Am Coll Cardiol. 2005 Sep 06; 46(5):906-19. PMID: 16139143.
    View in: PubMed
  275. Pinto DS, Skolnick AH, Kirtane AJ, Murphy SA, Barron HV, Giugliano RP, Cannon CP, Braunwald E, Gibson CM. U-shaped relationship of blood glucose with adverse outcomes among patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2005 Jul 05; 46(1):178-80. PMID: 15992655.
    View in: PubMed
  276. Giugliano RP, Newby LK, Harrington RA, Gibson CM, Van de Werf F, Armstrong P, Montalescot G, Gilbert J, Strony JT, Califf RM, Braunwald E. The early glycoprotein IIb/IIIa inhibition in non-ST-segment elevation acute coronary syndrome (EARLY ACS) trial: a randomized placebo-controlled trial evaluating the clinical benefits of early front-loaded eptifibatide in the treatment of patients with non-ST-segment elevation acute coronary syndrome--study design and rationale. Am Heart J. 2005 Jun; 149(6):994-1002. PMID: 15976780.
    View in: PubMed
  277. Cannon CP, Braunwald E, McCabe CH, Grayston JT, Muhlestein B, Giugliano RP, Cairns R, Skene AM. Antibiotic treatment of Chlamydia pneumoniae after acute coronary syndrome. N Engl J Med. 2005 Apr 21; 352(16):1646-54. PMID: 15843667.
    View in: PubMed
  278. Sabatine MS, Morrow DA, Giugliano RP, Burton PB, Murphy SA, McCabe CH, Gibson CM, Braunwald E. Association of hemoglobin levels with clinical outcomes in acute coronary syndromes. Circulation. 2005 Apr 26; 111(16):2042-9. PMID: 15824203.
    View in: PubMed
  279. Giugliano RP, Braunwald E. 2004 ACC/AHA guideline for the management of patients with STEMI: the implications for clinicians. Nat Clin Pract Cardiovasc Med. 2005 Mar; 2(3):114-5. PMID: 16265435.
    View in: PubMed
  280. Rebeiz AG, Johanson P, Green CL, Crater SW, Roe MT, Langer A, Giugliano RP, Lincoff AM, Newby LK, Harrington RA, Topol EJ, Califf RM, Wagner GS, Krucoff MW. Comparison of ST-segment resolution with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy versus fibrinolytic alone (data from four clinical trials). Am J Cardiol. 2005 Mar 01; 95(5):611-4. PMID: 15721101.
    View in: PubMed
  281. Kirtane AJ, Kosmidou I, Karmpaliotis D, Murphy SA, Giugliano RP, Cannon CP, Antman EM, Braunwald E, Gibson CM. Association of culprit lesion calcium with angiographic and clinical outcomes in patients with ST-elevation myocardial infarction treated with fibrinolytic therapy. Am J Cardiol. 2005 Feb 01; 95(3):337-42. PMID: 15670541.
    View in: PubMed
  282. Ly HQ, Kirtane AJ, Buros J, Giugliano RP, Popma JJ, Antman EM, Harrington RA, Ohman EM, Gibson CM. Angiographic and clinical outcomes associated with direct versus conventional stenting among patients treated with fibrinolytic therapy for ST-elevation acute myocardial infarction. Am J Cardiol. 2005 Feb 01; 95(3):383-6. PMID: 15670549.
    View in: PubMed
  283. Gibson CM, Kirtane AJ, Boundy K, Ly H, Karmpaliotis D, Murphy SA, Giugliano RP, Cannon CP, Antman EM, Braunwald E. Association of a negative residual stenosis following rescue/adjunctive percutaneous coronary intervention with impaired myocardial perfusion and adverse outcomes among ST-segment elevation myocardial infarction patients. J Am Coll Cardiol. 2005 Feb 01; 45(3):357-62. PMID: 15680712.
    View in: PubMed
  284. Kirtane AJ, Martinezclark P, Rahman AM, Ray KK, Karmpaliotis D, Murphy SA, Giugliano RP, Cannon CP, Antman EM, Roe MT, Harrington RA, Ohman EM, Braunwald E, Gibson CM. Association of smoking with improved myocardial perfusion and the angiographic characterization of myocardial tissue perfusion after fibrinolytic therapy for ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2005 Jan 18; 45(2):321-3. PMID: 15653037.
    View in: PubMed
  285. Kirtane AJ, Weisbord A, Karmpaliotis D, Murphy SA, Giugliano RP, Cannon CP, Antman EM, Ohman EM, Roe MT, Braunwald E, Gibson CM. Relation of impaired Thrombolysis In Myocardial Infarction myocardial perfusion grades to residual thrombus following the restoration of epicardial patency in ST-elevation myocardial infarction. Am J Cardiol. 2005 Jan 15; 95(2):224-7. PMID: 15642554.
    View in: PubMed
  286. Kashani A, Gibson CM, Murphy SA, Sabatine MS, Morrow DA, Antman EM, Giugliano RP. Angiography and revascularization in patients with heart failure following fibrinolytic therapy for ST-elevation acute myocardial infarction. Am J Cardiol. 2005 Jan 15; 95(2):228-33. PMID: 15642555.
    View in: PubMed
  287. ADVANCE MI Investigators. Facilitated percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: results from teh prematurely terminated Addressing the Value of facilitated Angioplasty after Combination therapy of Eptifibatide monotherapy in acute Myocardial Infarction (ADVANCE MI) trial. American Heart Journal. 2005; 150(1):116-22.
  288. Giugliano RP. MD Conference Express. 2005.
  289. Giugliano RP, Braunwald E. Baseline troponin in acute coronary syndromes managed invasively. Am J Med. 2004 Dec 15; 117(12):963-5. PMID: 15629738.
    View in: PubMed
  290. Turakhia MP, Murphy SA, Pinto TL, Antman EM, Giugliano RP, Cannon CP, Braunwald E, Gibson CM. Association of platelet count with residual thrombus in the myocardial infarct-related coronary artery among patients treated with fibrinolytic therapy for ST-segment elevation acute myocardial infarction. Am J Cardiol. 2004 Dec 01; 94(11):1406-10. PMID: 15566912.
    View in: PubMed
  291. Gibson CM, Dumaine RL, Gelfand EV, Murphy SA, Morrow DA, Wiviott SD, Giugliano RP, Cannon CP, Antman EM, Braunwald E. Association of glomerular filtration rate on presentation with subsequent mortality in non-ST-segment elevation acute coronary syndrome; observations in 13,307 patients in five TIMI trials. Eur Heart J. 2004 Nov; 25(22):1998-2005. PMID: 15541835.
    View in: PubMed
  292. Karmpaliotis D, Turakhia MP, Kirtane AJ, Murphy SA, Kosmidou I, Morrow DA, Giugliano RP, Cannon CP, Antman EM, Braunwald E, Gibson CM. Sequential risk stratification using TIMI risk score and TIMI flow grade among patients treated with fibrinolytic therapy for ST-segment elevation acute myocardial infarction. Am J Cardiol. 2004 Nov 01; 94(9):1113-7. PMID: 15518603.
    View in: PubMed
  293. Kashani A, Giugliano RP, Antman EM, Morrow DA, Gibson CM, Murphy SA, Braunwald E. Severity of heart failure, treatments, and outcomes after fibrinolysis in patients with ST-elevation myocardial infarction. Eur Heart J. 2004 Oct; 25(19):1702-10. PMID: 15451148.
    View in: PubMed
  294. Gibson CM, Murphy SA, Kirtane AJ, Giugliano RP, Cannon CP, Antman EM, Braunwald E. Association of duration of symptoms at presentation with angiographic and clinical outcomes after fibrinolytic therapy in patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2004 Sep 01; 44(5):980-7. PMID: 15337207.
    View in: PubMed
  295. Wiviott SD, Morrow DA, Frederick PD, Giugliano RP, Gibson CM, McCabe CH, Cannon CP, Antman EM, Braunwald E. Performance of the thrombolysis in myocardial infarction risk index in the National Registry of Myocardial Infarction-3 and -4: a simple index that predicts mortality in ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2004 Aug 18; 44(4):783-9. PMID: 15312859.
    View in: PubMed
  296. Gibson CM, Murphy SA, Morrow DA, Aroesty JM, Gibbons RJ, Gourlay SG, Barron HV, Giugliano RP, Antman EM, Braunwald E. Angiographic perfusion score: an angiographic variable that integrates both epicardial and tissue level perfusion before and after facilitated percutaneous coronary intervention in acute myocardial infarction. Am Heart J. 2004 Aug; 148(2):336-40. PMID: 15309006.
    View in: PubMed
  297. Gibson CM, Jennings LK, Murphy SA, Lorenz DP, Giugliano RP, Harrington RA, Cholera S, Krishnan R, Califf RM, Braunwald E. Association between platelet receptor occupancy after eptifibatide (integrilin) therapy and patency, myocardial perfusion, and ST-segment resolution among patients with ST-segment-elevation myocardial infarction: an INTEGRITI (Integrilin and Tenecteplase in Acute Myocardial Infarction) substudy. Circulation. 2004 Aug 10; 110(6):679-84. PMID: 15262838.
    View in: PubMed
  298. Gardner GS, Frisch DR, Murphy SA, Kirtane AJ, Giugliano RP, Antman EM, Braunwald E, Gibson CM. Effect of rescue or adjunctive percutaneous coronary intervention of the culprit artery after fibrinolytic administration on epicardial flow in nonculprit arteries. Am J Cardiol. 2004 Jul 15; 94(2):178-81. PMID: 15246895.
    View in: PubMed
  299. Gibson CM, Bigelow B, James D, Tepper MR, Murphy SA, Kirtane AJ, Giugliano RP, Cannon CP, Antman EM. Association of lesion complexity following fibrinolytic administration with mortality in ST-elevation myocardial infarction. Am J Cardiol. 2004 Jul 01; 94(1):108-11. PMID: 15219518.
    View in: PubMed
  300. Morrow DA, Antman EM, Murphy SA, Assmann SF, Giugliano RP, Cannon CP, Michael Gibson C, McCabe CH, Barron HV, Van De Werf F, Braunwald E. The Risk Score Profile: a novel approach to characterising the risk of populations enrolled in clinical studies. Eur Heart J. 2004 Jul; 25(13):1139-45. PMID: 15231372.
    View in: PubMed
  301. Kirtane AJ, Bui A, Murphy SA, Karmpaliotis D, Kosmidou I, Boundy K, Rahman A, Pinto DS, Aroesty JM, Giugliano RP, Cannon CP, Antman EM, Gibson CM. Association of epicardial and tissue-level reperfusion with left ventricular end-diastolic pressures in ST-elevation myocardial infarction. J Thromb Thrombolysis. 2004 Jun; 17(3):177-84. PMID: 15353915.
    View in: PubMed
  302. Giugliano RP, Sabatine MS, Gibson CM, Roe MT, Harrington RA, Murphy SA, Morrow DA, Antman EM, Braunwald E. Combined assessment of thrombolysis in myocardial infarction flow grade, myocardial perfusion grade, and ST-segment resolution to evaluate epicardial and myocardial reperfusion. Am J Cardiol. 2004 Jun 01; 93(11):1362-7, A5-6. PMID: 15165915.
    View in: PubMed
  303. Allen LA, O'Donnell CJ, Giugliano RP, Camargo CA, Lloyd-Jones DM. Care concordant with guidelines predicts decreased long-term mortality in patients with unstable angina pectoris and non-ST-elevation myocardial infarction. Am J Cardiol. 2004 May 15; 93(10):1218-22. PMID: 15135692.
    View in: PubMed
  304. Gibson CM, Karha J, Giugliano RP, Roe MT, Murphy SA, Harrington RA, Green CL, Schweiger MJ, Miklin JS, Baran KW, Palmeri S, Braunwald E, Krucoff MW. Association of the timing of ST-segment resolution with TIMI myocardial perfusion grade in acute myocardial infarction. Am Heart J. 2004 May; 147(5):847-52. PMID: 15131541.
    View in: PubMed
  305. Gibson CM, Karha J, Murphy SA, de Lemos JA, Morrow DA, Giugliano RP, Roe MT, Harrington RA, Cannon CP, Antman EM, Califf RM, Braunwald E. Association of a pulsatile blood flow pattern on coronary arteriography and short-term clinical outcomes in acute myocardial infarction. J Am Coll Cardiol. 2004 Apr 07; 43(7):1170-6. PMID: 15063425.
    View in: PubMed
  306. Roe MT, Green CL, Giugliano RP, Gibson CM, Baran K, Greenberg M, Palmeri ST, Crater S, Trollinger K, Hannan K, Harrington RA, Krucoff MW. Improved speed and stability of ST-segment recovery with reduced-dose tenecteplase and eptifibatide compared with full-dose tenecteplase for acute ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2004 Feb 18; 43(4):549-56. PMID: 14975462.
    View in: PubMed
  307. Wiviott SD, Cannon CP, Morrow DA, Murphy SA, Gibson CM, McCabe CH, Sabatine MS, Rifai N, Giugliano RP, DiBattiste PM, Demopoulos LA, Antman EM, Braunwald E. Differential expression of cardiac biomarkers by gender in patients with unstable angina/non-ST-elevation myocardial infarction: a TACTICS-TIMI 18 (Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy-Thrombolysis In Myocardial Infarction 18) substudy. Circulation. 2004 Feb 10; 109(5):580-6. PMID: 14769678.
    View in: PubMed
  308. Sabatine MS, Morrow DA, Giugliano RP, Murphy SA, Demopoulos LA, DiBattiste PM, Weintraub WS, McCabe CH, Antman EM, Cannon CP, Braunwald E. Implications of upstream glycoprotein IIb/IIIa inhibition and coronary artery stenting in the invasive management of unstable angina/non-ST-elevation myocardial infarction: a comparison of the Thrombolysis In Myocardial Infarction (TIMI) IIIB trial and the Treat angina with Aggrastat and determine Cost of Therapy with Invasive or Conservative Strategy (TACTICS)-TIMI 18 trial. Circulation. 2004 Feb 24; 109(7):874-80. PMID: 14757697.
    View in: PubMed
  309. Kashani A, Antman EM, Morrow DA, Giugliano RP. Causes of Death in Patients with ST Elevation Myocardial Infarction Treated with Fibrinolysis. J Am Coll Cardiol. 2004; 43(Suppl A):263A.
  310. Martinezclark P, Karmpalitotis D, Murphy SA, Wiviott SD, Bigelow B, Kosmidou I, Chang A, Cannon CP, Giugliano RP, Gibson CM. The Association of Race with Angiographic and Clinical Outcomes Following Fibrinolytic Administration. J Am Coll Cardiol. 2004; 43(Suppl A):305A.
  311. Giugliano RP, Braunwald E. Selecting the best reperfusion strategy in ST-elevation myocardial infarction: it's all a matter of time. Circulation. 2003 Dec 09; 108(23):2828-30. PMID: 14662688.
    View in: PubMed
  312. Hobbach HP, Gibson CM, Giugliano RP, Hundertmark J, Schaeffer C, Tscherleniak W, Schuster P. The prognostic value of serum creatinine on admission in fibrinolytic-eligible patients with acute myocardial infarction. J Thromb Thrombolysis. 2003 Dec; 16(3):167-74. PMID: 15087603.
    View in: PubMed
  313. Giraldez RR, Antman EM, Giugliano RP. The Challenge of Treating ST-Segment Elevation Myocardial Infarction in the Elderly. Bhatt DL, Merli GJ, editors. In Thrombosis Clinic. 2003; 1(1).
  314. Lloyd-Jones DM, Camargo CA, Allen LA, Giugliano RP, O'Donnell CJ. Predictors of long-term mortality after hospitalization for primary unstable angina pectoris and non-ST-elevation myocardial infarction. Am J Cardiol. 2003 Nov 15; 92(10):1155-9. PMID: 14609588.
    View in: PubMed
  315. Gibson CM, Pinto DS, Murphy SA, Morrow DA, Hobbach HP, Wiviott SD, Giugliano RP, Cannon CP, Antman EM, Braunwald E. Association of creatinine and creatinine clearance on presentation in acute myocardial infarction with subsequent mortality. J Am Coll Cardiol. 2003 Nov 05; 42(9):1535-43. PMID: 14607434.
    View in: PubMed
  316. Wong GC, Giugliano RP. Low-molecular-weight heparins for the treatment of acute coronary syndromes. Semin Vasc Med. 2003 Nov; 3(4):391-402. PMID: 15199446.
    View in: PubMed
  317. Giugliano RP, Braunwald E. Improving antithrombotic treatment in patients after myocardial infarction. Lancet. 2003 Sep 06; 362(9386):757. PMID: 13678866.
    View in: PubMed
  318. Christenson RH, Leino EV, Giugliano RP, Bahr RD. Usefulness of prodromal unstable angina pectoris in predicting better survival and smaller infarct size in acute myocardial infarction (The InTIME-II Prodromal Symptoms Substudy). Am J Cardiol. 2003 Sep 01; 92(5):598-600. PMID: 12943885.
    View in: PubMed
  319. Gibson CM, Gibson WJ, Murphy SA, Marble SJ, McCabe CH, Turakhia MP, Kirtane AJ, Karha J, Aroesty JM, Giugliano RP, Antman EM. Association of the Fibonacci Cascade with the distribution of coronary artery lesions responsible for ST-segment elevation myocardial infarction. Am J Cardiol. 2003 Sep 01; 92(5):595-7. PMID: 12943884.
    View in: PubMed
  320. Gibson CM, Karha J, Murphy SA, James D, Morrow DA, Cannon CP, Giugliano RP, Antman EM, Braunwald E. Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the Thrombolysis in Myocardial Infarction trials. J Am Coll Cardiol. 2003 Jul 02; 42(1):7-16. PMID: 12849652.
    View in: PubMed
  321. Gibson CM, Kirtane AJ, Murphy SA, Karha J, Cannon CP, Giugliano RP, Roe MT, Harrington RA, Ohman EM, Antman EM. Distance from the coronary ostium to the culprit lesion in acute ST-elevation myocardial infarction and its implications regarding the potential prevention of proximal plaque rupture. J Thromb Thrombolysis. 2003 Jun; 15(3):189-96. PMID: 14739628.
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  322. Giugliano GR, Giugliano RP, Gibson CM, Kuntz RE. Meta-analysis of corticosteroid treatment in acute myocardial infarction. Am J Cardiol. 2003 May 01; 91(9):1055-9. PMID: 12714146.
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  323. Giugliano RP, Roe MT, Harrington RA, Gibson CM, Zeymer U, Van de Werf F, Baran KW, Hobbach HP, Woodlief LH, Hannan KL, Greenberg S, Miller J, Kitt MM, Strony J, McCabe CH, Braunwald E, Califf RM. Combination reperfusion therapy with eptifibatide and reduced-dose tenecteplase for ST-elevation myocardial infarction: results of the integrilin and tenecteplase in acute myocardial infarction (INTEGRITI) Phase II Angiographic Trial. J Am Coll Cardiol. 2003 Apr 16; 41(8):1251-60. PMID: 12706917.
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  324. Wong GC, Giugliano RP, Antman EM. Use of low-molecular-weight heparins in the management of acute coronary artery syndromes and percutaneous coronary intervention. JAMA. 2003 Jan 15; 289(3):331-42. PMID: 12525234.
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  325. Ilkhanoff L, O'Donnell CJ, Camargo CA, O'Halloran D, Giugliano RP, Lloyd-Jones DM. The TIMI Risk Index Predicts In-hospital and Long-term Mortality in Unselected Patients with Myocardial Infarction. Acad Emerg Med. 2003; 10:429-30.
  326. Walsh CR, O'Donnell CJ, Camargo CA, Giugliano RP, Lloyd-Jones DM. Elevated serum creatinine is associated with 1-year mortality after acute myocardial infarction. Am Heart J. 2002 Dec; 144(6):1003-11. PMID: 12486424.
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  327. Morrow DA, Antman EM, Sayah A, Schuhwerk KC, Giugliano RP, deLemos JA, Waller M, Cohen SA, Rosenberg DG, Cutler SS, McCabe CH, Walls RM, Braunwald E. Evaluation of the time saved by prehospital initiation of reteplase for ST-elevation myocardial infarction: results of The Early Retavase-Thrombolysis in Myocardial Infarction (ER-TIMI) 19 trial. J Am Coll Cardiol. 2002 Jul 03; 40(1):71-7. PMID: 12103258.
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  328. Sabatine MS, McCabe CH, Morrow DA, Giugliano RP, de Lemos JA, Cohen M, Antman EM, Braunwald E. Identification of patients at high risk for death and cardiac ischemic events after hospital discharge. Am Heart J. 2002 Jun; 143(6):966-70. PMID: 12075250.
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  329. Antman EM, Cooper HA, Gibson CM, de Lemos JA, McCabe CH, Giugliano RP, Coussement P, Murphy S, Scherer J, Anderson K, Van de Werf F, Braunwald E. Determinants of improvement in epicardial flow and myocardial perfusion for ST elevation myocardial infarction; insights from TIMI 14 and InTIME-II. Eur Heart J. 2002 Jun; 23(12):928-33. PMID: 12069446.
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  330. Giugliano RP, Mousa SA, Willerson JT. Antiplatelet overview. Sasahara AA, Loscalzo J, editors. New Therapeutic Agents in Thrombosis and Thrombolysis. 2002.
  331. Giugliano RP. Lanoteplase. Sasahara AA, Loscalzo J, editors. New Therapeutic Agents in Thrombosis and Thrombolysis. 2002.
  332. Mousa SA, Konstantopoulos K, Giugliano RP. Oral antiplatelet therapies beyond aspirin and thienopyridines. Sasahara AA, Loscalzo J, editors. New Therapeutic Agents in Thrombosis and Thrombolysis. 2002.
  333. Giugliano RP, Antman EM. Caeteris paribus - all things being equal. Eur Heart J. 2001 Dec; 22(24):2221-3. PMID: 11728139.
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  334. Morrow DA, Antman EM, Giugliano RP, Cairns R, Charlesworth A, Murphy SA, de Lemos JA, McCabe CH, Braunwald E. A simple risk index for rapid initial triage of patients with ST-elevation myocardial infarction: an InTIME II substudy. Lancet. 2001 Nov 10; 358(9293):1571-5. PMID: 11716882.
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  335. Llevadot J, Giugliano RP, Antman EM, Wilcox RG, Gurfinkel EP, Henry T, McCabe CH, Charlesworth A, Thompson S, Nicolau JC, Tebbe U, Sadowski Z, Braunwald E. Availability of on-site catheterization and clinical outcomes in patients receiving fibrinolysis for ST-elevation myocardial infarction. Eur Heart J. 2001 Nov; 22(22):2104-15. PMID: 11686667.
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  336. Schweiger MJ, Cannon CP, Murphy SA, Gibson CM, Cook JR, Giugliano RP, Changezi HU, Antman EM, Braunwald E. Early coronary intervention following pharmacologic therapy for acute myocardial infarction (the combined TIMI 10B-TIMI 14 experience). Am J Cardiol. 2001 Oct 15; 88(8):831-6. PMID: 11676942.
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  337. Morrow DA, Antman EM, Parsons L, de Lemos JA, Cannon CP, Giugliano RP, McCabe CH, Barron HV, Braunwald E. Application of the TIMI risk score for ST-elevation MI in the National Registry of Myocardial Infarction 3. JAMA. 2001 Sep 19; 286(11):1356-9. PMID: 11560541.
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  338. Giugliano RP, Llevadot J, Wilcox RG, Gurfinkel EP, McCabe CH, Charlesworth A, Thompson SL, Antman EM, Braunwald E. Geographic variation in patient and hospital characteristics, management, and clinical outcomes in ST-elevation myocardial infarction treated with fibrinolysis. Results from InTIME-II. Eur Heart J. 2001 Sep; 22(18):1702-15. PMID: 11511120.
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  339. de Lemos JA, Morrow DA, Gibson CM, Murphy SA, Rifai N, Tanasijevic M, Giugliano RP, Schuhwerk KC, McCabe CH, Cannon CP, Antman EM, Braunwald E. Early noninvasive detection of failed epicardial reperfusion after fibrinolytic therapy. Am J Cardiol. 2001 Aug 15; 88(4):353-8. PMID: 11545753.
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  340. Llevadot J, Giugliano RP, Antman EM. Bolus fibrinolytic therapy in acute myocardial infarction. JAMA. 2001 Jul 25; 286(4):442-9. PMID: 11466123.
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  341. Giugliano RP, McCabe CH, Antman EM, Cannon CP, Van de Werf F, Wilcox RG, Braunwald E. Lower-dose heparin with fibrinolysis is associated with lower rates of intracranial hemorrhage. Am Heart J. 2001 May; 141(5):742-50. PMID: 11320361.
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  342. Giugliano RP. TNK-tPA, a new thrombolytic. Braunwauld E, editor. Harrison's Principles of Internal Medicine (http://www.harrisonsonline.com). 2001.
  343. Giugliano RP, Cannon CP. Antiplatelet agents. Antman EM, editor. Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease. 2001.
  344. Giugliano RP. Low molecular weight heparin and direct thrombin inhibitors in acute coronary syndromes. Goldhaber SZ, Ridker PM, editors. Thrombosis and Thromboembolism. 2001.
  345. Morrow DA, Antman EM, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E, Murphy SA, Charlesworth A, Cairns R. Death rates versus deaths. Circulation. 2001; 104:e8.
  346. Roe MT, Giugliano RP, Harrington RA, Gibson CM, Strony J, Kitt MM, et al. Combination Reperfusion Therapy for Acute Myocardial Infarction with Eptifibatide and Tenecteplase: Design and Methodology of the (INTEGRIlin and Tenecteplase for acute myocardial infarction) INTEGRITI Trial. Heart Drug. 2001; 1:5-13.
  347. Giugliano RP. Late-breaking trial of invasive versus conservative strategies in unstable angina and non-Q-wave myocardial infarction following treatment with Tirofiban (TACTICS-TIMI 18 Trial). Cardiology Scientific Update. 2001.
  348. de Lemos JA, Antman EM, Giugliano RP, Morrow DA, McCabe CH, Cutler SS, Charlesworth A, Schröder R, Braunwald E. Comparison of a 60- versus 90-minute determination of ST-segment resolution after thrombolytic therapy for acute myocardial infarction. In TIME-II Investigators. Intravenous nPA for Treatment of Infarcting Myocardium Early-II. Am J Cardiol. 2000 Dec 01; 86(11):1235-7, A5. PMID: 11090796.
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  349. Antman EM, Gibson CM, de Lemos JA, Giugliano RP, McCabe CH, Coussement P, Menown I, Nienaber CA, Rehders TC, Frey MJ, Van der Wieken R, Andresen D, Scherer J, Anderson K, Van de Werf F, Braunwald E. Combination reperfusion therapy with abciximab and reduced dose reteplase: results from TIMI 14. The Thrombolysis in Myocardial Infarction (TIMI) 14 Investigators. Eur Heart J. 2000 Dec; 21(23):1944-53. PMID: 11071800.
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  350. Walsh CR, Lloyd-Jones DM, Camargo CA, Giugliano RP, O'Donnell CJ. Clinical trials of unfractionated heparin and low-molecular-weight heparin in addition to aspirin for the treatment of unstable angina pectoris: do the results apply to all patients? Am J Cardiol. 2000 Nov 01; 86(9):908-12. PMID: 11053697.
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  351. Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E. TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for treatment of infarcting myocardium early II trial substudy. Circulation. 2000 Oct 24; 102(17):2031-7. PMID: 11044416.
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  352. Januzzi JL, Hahn SS, Chae CU, Giugliano R, Lewandrowski K, Theroux P, Jang IK. Effects of tirofiban plus heparin versus heparin alone on troponin I levels in patients with acute coronary syndromes. Am J Cardiol. 2000 Oct 01; 86(7):713-7. PMID: 11018188.
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  353. De Lemos JA, Antman EM, Giugliano RP, Morrow DA, McCabe CH, Charlesworth A, Schröder R, Braunwald E. Very early risk stratification after thrombolytic therapy with a bedside myoglobin assay and the 12-lead electrocardiogram. Am Heart J. 2000 Sep; 140(3):373-8. PMID: 10966533.
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  354. de Lemos JA, Antman EM, Morrow DA, Llevadot J, Giugliano RP, Coulter SA, Schuhwerk KC, Arslanian S, McCabe CH, Gibson CM, Rifai N. Heart-type fatty acid binding protein as a marker of reperfusion after thrombolytic therapy. Clin Chim Acta. 2000 Aug; 298(1-2):85-97. PMID: 10876006.
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  355. Llevadot J, Giugliano RP. New Thrombolytic Agents: Does Direct Angioplasty Still Have a Role? Curr Interv Cardiol Rep. 2000 Aug; 2(3):250-257. PMID: 11096674.
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  356. Giugliano RP, McCabe CH, Sequeira RF, Frey MJ, Henry TD, Piana RN, Tamby JF, Jensen BK, Nicolas SB, Jennings LK, Wise RJ, Braunwald E. First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: results of the TIMI 15A and 15B trials. Am Heart J. 2000 Jul; 140(1):81-93. PMID: 10874267.
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  357. Giugliano RP, Lloyd-Jones DM, Camargo CA, Makary MA, O'Donnell CJ. Association of unstable angina guideline care with improved survival. Arch Intern Med. 2000 Jun 26; 160(12):1775-80. PMID: 10871970.
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  358. Llevadot J, Giugliano RP, McCabe CH, Cannon CP, Antman EM, Murphy S, Gibson CM. Degree of residual stenosis in the culprit coronary artery after thrombolytic administration (Thrombolysis In Myocardial Infarction [TIMI] trials). Am J Cardiol. 2000 Jun 15; 85(12):1409-13. PMID: 10856384.
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  359. Coulter SA, Cannon CP, Ault KA, Antman EM, Van de Werf F, Adgey AA, Gibson CM, Giugliano RP, Mascelli MA, Scherer J, Barnathan ES, Braunwald E, Kleiman NS. High levels of platelet inhibition with abciximab despite heightened platelet activation and aggregation during thrombolysis for acute myocardial infarction: results from TIMI (thrombolysis in myocardial infarction) 14. Circulation. 2000 Jun 13; 101(23):2690-5. PMID: 10851205.
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  360. Lloyd-Jones DM, Camargo CA, Giugliano RP, O'Donnell CJ. Effect of leukocytosis at initial examination on prognosis in patients with primary unstable angina. Am Heart J. 2000 May; 139(5):867-73. PMID: 10783221.
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  361. de Lemos JA, Antman EM, Giugliano RP, McCabe CH, Murphy SA, Van de Werf F, Gibson CM, Braunwald E. ST-segment resolution and infarct-related artery patency and flow after thrombolytic therapy. Thrombolysis in Myocardial Infarction (TIMI) 14 investigators. Am J Cardiol. 2000 Feb 01; 85(3):299-304. PMID: 11078296.
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  362. Llevadot J, Coulter SA, Giugliano RP. A practical approach to the diagnosis and management of thrombocytopenia associated with glycoprotein IIb/IIIa receptor inhibitors. J Thromb Thrombolysis. 2000 Feb; 9(2):175-80. PMID: 10613999.
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  363. de Lemos JA, Antman EM, Gibson CM, McCabe CH, Giugliano RP, Murphy SA, Coulter SA, Anderson K, Scherer J, Frey MJ, Van Der Wieken R, Van De Werf F, Braunwald E. Abciximab improves both epicardial flow and myocardial reperfusion in ST-elevation myocardial infarction. Observations from the TIMI 14 trial. Circulation. 2000 Jan 25; 101(3):239-43. PMID: 10645918.
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  364. Cannon CP, Giugliano RP. TNK-tPA (tenecteplase): The single bolus thrombolytic agent for the new millennium. Cardiology Scientific Update. 2000.
  365. Giugliano RP, Llevadot J. Pharmacology and clinical trial results of lanoteplase in acute myocardial infarction. Exp Opin Invest Drugs. 2000; 9:2689-94.
  366. Llevadot J, Giugliano RP. New thrombolytic agents: Does direct angioplasty still have a role?. Curr Interv Cardiol Reports. 2000; 2:29-256.
  367. Holper EM, Giugliano RP, Antman EM. Glycoprotein IIb/IIIa inhibitors in acute ST segment elevation myocardial infarction. Coron Artery Dis. 1999 Dec; 10(8):567-73. PMID: 10599535.
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  368. Gibson CM, Murphy S, Menown IB, Sequeira RF, Greene R, Van de Werf F, Schweiger MJ, Ghali M, Frey MJ, Ryan KA, Marble SJ, Giugliano RP, Antman EM, Cannon CP, Braunwald E. Determinants of coronary blood flow after thrombolytic administration. TIMI Study Group. Thrombolysis in Myocardial Infarction. J Am Coll Cardiol. 1999 Nov 01; 34(5):1403-12. PMID: 10551685.
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  369. Lloyd-Jones DM, Camargo CA, Giugliano RP, Walsh CR, O'Donnell CJ. Characteristics and prognosis of patients with suspected acute myocardial infarction and elevated MB relative index but normal total creatine kinase. Am J Cardiol. 1999 Nov 01; 84(9):957-62. PMID: 10569646.
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  370. Gibson CM, Ryan KA, Murphy SA, Mesley R, Marble SJ, Giugliano RP, Cannon CP, Antman EM, Braunwald E. Impaired coronary blood flow in nonculprit arteries in the setting of acute myocardial infarction. The TIMI Study Group. Thrombolysis in myocardial infarction. J Am Coll Cardiol. 1999 Oct; 34(4):974-82. PMID: 10520778.
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  371. Jang IK, Brown DF, Giugliano RP, Anderson HV, Losordo D, Nicolau JC, Dutra OP, Bazzino O, Viamonte VM, Norbady R, Liprandi AS, Massey TJ, Dinsmore R, Schwarz RP. A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol. 1999 Jun; 33(7):1879-85. PMID: 10362188.
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  372. Antman EM, Giugliano RP, Gibson CM, McCabe CH, Coussement P, Kleiman NS, Vahanian A, Adgey AA, Menown I, Rupprecht HJ, Van der Wieken R, Ducas J, Scherer J, Anderson K, Van de Werf F, Braunwald E. Abciximab facilitates the rate and extent of thrombolysis: results of the thrombolysis in myocardial infarction (TIMI) 14 trial. The TIMI 14 Investigators. Circulation. 1999 Jun 01; 99(21):2720-32. PMID: 10351964.
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  373. Gibson CM, Ryan KA, Kelley M, Rizzo MJ, Mesley R, Murphy S, Swanson J, Marble SJ, Dodge JT, Giugliano RP, Cannon CP, Antman EM. Methodologic drift in the assessment of TIMI grade 3 flow and its implications with respect to the reporting of angiographic trial results. The TIMI Study Group. Am Heart J. 1999 Jun; 137(6):1179-84. PMID: 10347349.
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  374. Giugliano RP, Braunwauld E. Immediate PTCA and thrombolytic therapy, the TIMI IIa trial. Nash IS, Fuster V, editors. Efficacy of myocardial infarction therapy: An evaluation of clinical trials evidence. 1999.
  375. Cannon CP, Gibson CM, McCabe CH, Adgey AA, Schweiger MJ, Sequeira RF, Grollier G, Giugliano RP, Frey M, Mueller HS, Steingart RM, Weaver WD, Van de Werf F, Braunwald E. TNK-tissue plasminogen activator compared with front-loaded alteplase in acute myocardial infarction: results of the TIMI 10B trial. Thrombolysis in Myocardial Infarction (TIMI) 10B Investigators. Circulation. 1998 Dec 22-29; 98(25):2805-14. PMID: 9860780.
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  376. Lapuerta P, L'Italien G, Giugliano R, Eagle KA. Neural networks, logistic regression, and calibration: a reply. Med Decis Making. 1998 Oct-Dec; 18(4):444-6. PMID: 10372588.
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  377. Boeve TJ, Reed GL, Titus J, Janssens S, Giugliano RP, Torchiana D, Daggett W, Schwarz R, Jang IK. Comparison of Argatroban and Hirudin for the Reperfusion of Thrombotic Arterial Occlusion by Tissue Plasminogen Activator. J Thromb Thrombolysis. 1998 Sep; 6(2):103-108. PMID: 10751791.
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  378. Giugliano RP. Drug-Induced Thrombocytopenia: Is it a Serious Concern for Glycoprotein IIb/IIIa Receptor Inhibitors? J Thromb Thrombolysis. 1998 Jul; 5(3):191-202. PMID: 10767115.
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  379. Giugliano RP, Camargo CA, Lloyd-Jones DM, Zagrodsky JD, Alexis JD, Eagle KA, Fuster V, O'Donnell CJ. Elderly patients receive less aggressive medical and invasive management of unstable angina: potential impact of practice guidelines. Arch Intern Med. 1998 May 25; 158(10):1113-20. PMID: 9605783.
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  380. Lloyd-Jones DM, Camargo CA, Lapuerta P, Giugliano RP, O'Donnell CJ. Electrocardiographic and clinical predictors of acute myocardial infarction in patients with unstable angina pectoris. Am J Cardiol. 1998 May 15; 81(10):1182-6. PMID: 9604942.
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  381. Lapuerta P, L'Italien GJ, Paul S, Hendel RC, Leppo JA, Fleisher LA, Cohen MC, Eagle KA, Giugliano RP. Neural network assessment of perioperative cardiac risk in vascular surgery patients. Med Decis Making. 1998 Jan-Mar; 18(1):70-5. PMID: 9456211.
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  382. Starr C (author) in consultation with Feigenbaum H, Giugliano RP, Lavie Jr CJ, Morrow DA, Pohost GM. New directions in cardiac testing. Patient Care. 1998; 32:62-81.
  383. Giugliano RP, Braunwald E. Clinical use of glycoprotein IIb/IIIa inhibitors. Braunwald E, editor. Harrison's Principles o Internal Medicine On-Line (http://www.harrisonsonline.com). 1998.
  384. Serebruany VL, Jang IK, Giugliano RP, Massey TJ, Schwarz Jr . A Randomized, Blinded Study of Two Doses of Novastan(R) (Brand of Argatroban) Versus Heparin as Adjunctive Therapy to Recombinant Tissue Plasminogen Activator (Accelerated Administration) in Acute Myocardial Infarction: Rationale and Design of the Myocardial Infarction using Novastan(R) and T-PA (MINT) Study. J Thromb Thrombolysis. 1998; 5(1):49-52. PMID: 10608050.
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  385. Giugliano RP, Antman EM, Braunwald E. Reexamination of the Thrombin Hypothesis: What We Have Learned from TIMI 9B and GUSTO IIb. J Thromb Thrombolysis. 1997; 4(3/4):321-323. PMID: 10639634.
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  386. Giugliano RP. Acute MI care pathway guidelines. 1996.
  387. Giugliano RP. Unstable angina/non-ST-elevation MI care pathways guidelines. 1996.
  388. Giugliano RP. Chest pain observation unit charter and care pathway guidelines. 1995.
  389. Giugliano RP, Eagle KA. Prognostic stratification of the patient after myocardial infarction in the thrombolytic era. ACC Current J Rev. 1995; 4:36-9.
  390. Giugliano RP, Eagle KA. Cardiology guidelines gain prominence. Am Coll of Card Newsletter. 1994; 23(1):4.
  391. Yeh V, Giugliano RP, Wolfe PR, Meyer R. Mycobacterial and cryptococcal splenic abscess in AIDS. Infectious Disease in Clinical Practice. 1994; 3:115-7.
  392. Giugliano RP. Koop's messages are preventive medicine, Letters to the editor. The Boston Globe. 1988; 18.
  393. Giugliano RP, Belbruno JJ. Multiphoton Induced Chemistry of Thiirane. J of Photochemistry. 1987; 37:263.
  394. Michelsen H, Giugliano RP, Belbruno JJ. Photochemistry and Photophysics of Small Heterocyclic Molecules. J of Phys Chem. 1985; 89:3034.
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