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Juan Martinez-Francois, Ph.D.

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Juan R. Martinez-Francois is a Lecturer on Neurobiology in the laboratory of Gary Yellen. He studies the molecular mechanisms linking metabolism and neuronal excitability with the hope of understanding, and possibly treating, epilepsy. Specifically, he is interested in the role of ATP-sensitive potassium channels in regulating the excitability of hippocampal neurons and in preventing epileptic seizures.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Tantama M, Martínez-François JR, Mongeon R, Yellen G. Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio. Nat Commun. 2013; 4:2550. PMID: 24096541.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  2. Giménez-Cassina A, Martínez-François JR, Fisher JK, Szlyk B, Polak K, Wiwczar J, Tanner GR, Lutas A, Yellen G, Danial NN. BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures. Neuron. 2012 May 24; 74(4):719-30. PMID: 22632729.
    Citations: 60     Fields:    Translation:AnimalsCells
  3. Tanner GR, Lutas A, Martínez-François JR, Yellen G. Single K ATP channel opening in response to action potential firing in mouse dentate granule neurons. J Neurosci. 2011 Jun 08; 31(23):8689-96. PMID: 21653873.
    Citations: 55     Fields:    Translation:AnimalsCells
  4. Martínez-François JR, Xu Y, Lu Z. Extracellular protons titrate voltage gating of a ligand-gated ion channel. J Gen Physiol. 2010 Aug; 136(2):179-87. PMID: 20624857.
    Citations: 2     Fields:    Translation:AnimalsCells
  5. Martínez-François JR, Lu Z. Intrinsic versus extrinsic voltage sensitivity of blocker interaction with an ion channel pore. J Gen Physiol. 2010 Feb; 135(2):149-67. PMID: 20100894.
    Citations: 6     Fields:    Translation:AnimalsCells
  6. Martínez-François JR, Xu Y, Lu Z. Mutations reveal voltage gating of CNGA1 channels in saturating cGMP. J Gen Physiol. 2009 Aug; 134(2):151-64. PMID: 19635856.
    Citations: 15     Fields:    Translation:AnimalsCells
  7. Martínez-François JR, Morales-Tlalpan V, Vaca L. Characterization of the maitotoxin-activated cationic current from human skin fibroblasts. J Physiol. 2002 Jan 01; 538(Pt 1):79-86. PMID: 11773318.
    Citations: 2     Fields:    Translation:HumansCells
  8. Aguilar-Salinas CA, Reyes-Rodríguez E, Ordóñez-Sánchez ML, Torres MA, Ramírez-Jiménez S, Domínguez-López A, Martínez-Francois JR, Velasco-Pérez ML, Alpizar M, García-García E, Gómez-Pérez F, Rull J, Tusié-Luna MT. Early-onset type 2 diabetes: metabolic and genetic characterization in the mexican population. J Clin Endocrinol Metab. 2001 Jan; 86(1):220-6. PMID: 11232004.
    Citations: 8     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.