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Juan Ramon Martinez-Francois, PH.D.

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Overview
Juan R. Martinez-Francois is a postdoctoral researcher in the laboratory of Gary Yellen. He studies the molecular mechanisms linking metabolism and neuronal excitability with the hope of understanding, and possibly treating, epilepsy. Specifically, he is interested in the role of ATP-sensitive potassium channels in regulating the excitability of hippocampal neurons and in preventing epileptic seizures.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tantama M, Martínez-François JR, Mongeon R, Yellen G. Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio. Nat Commun. 2013; 4:2550. PMID: 24096541.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  2. Giménez-Cassina A, Martínez-François JR, Fisher JK, Szlyk B, Polak K, Wiwczar J, Tanner GR, Lutas A, Yellen G, Danial NN. BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures. Neuron. 2012 May 24; 74(4):719-30. PMID: 22632729.
    Citations: 44     Fields:    Translation:AnimalsCells
  3. Tanner GR, Lutas A, Martínez-François JR, Yellen G. Single K ATP channel opening in response to action potential firing in mouse dentate granule neurons. J Neurosci. 2011 Jun 08; 31(23):8689-96. PMID: 21653873; PMCID: PMC3133530.
    Citations: 42     Fields:    Translation:AnimalsCells
  4. Martínez-François JR, Xu Y, Lu Z. Extracellular protons titrate voltage gating of a ligand-gated ion channel. J Gen Physiol. 2010 Aug; 136(2):179-87. PMID: 20624857; PMCID: PMC2912074.
    Citations: 2     Fields:    Translation:AnimalsCells
  5. Martínez-François JR, Lu Z. Intrinsic versus extrinsic voltage sensitivity of blocker interaction with an ion channel pore. J Gen Physiol. 2010 Feb; 135(2):149-67. PMID: 20100894; PMCID: PMC2812505.
    Citations: 6     Fields:    Translation:AnimalsCells
  6. Martínez-François JR, Xu Y, Lu Z. Mutations reveal voltage gating of CNGA1 channels in saturating cGMP. J Gen Physiol. 2009 Aug; 134(2):151-64. PMID: 19635856; PMCID: PMC2717697.
    Citations: 12     Fields:    Translation:AnimalsCells
  7. Martínez-François JR, Morales-Tlalpan V, Vaca L. Characterization of the maitotoxin-activated cationic current from human skin fibroblasts. J Physiol. 2002 Jan 01; 538(Pt 1):79-86. PMID: 11773318; PMCID: PMC2290027.
    Citations: 1     Fields:    Translation:HumansCells
  8. Aguilar-Salinas CA, Reyes-Rodríguez E, Ordóñez-Sánchez ML, Torres MA, Ramírez-Jiménez S, Domínguez-López A, Martínez-Francois JR, Velasco-Pérez ML, Alpizar M, García-García E, Gómez-Pérez F, Rull J, Tusié-Luna MT. Early-onset type 2 diabetes: metabolic and genetic characterization in the mexican population. J Clin Endocrinol Metab. 2001 Jan; 86(1):220-6. PMID: 11232004.
    Citations: 5     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.