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Paul B. Shyn, M.D.

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Biography
2008
Academic Transition Grant
2008
Wylie J. Dodds Research Award
2012
George Marina Memorial Radiology Residency Teaching Award

Overview
Primary Interests:

PET/CT imaging of malignancy and inflammation

Cross-sectional imaging-guided interventional procedures including tumor ablation

PET/CT-guided interventional radiology procedures

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Daye D, Staziaki PV, Furtado VF, Tabari A, Fintelmann FJ, Frenk NE, Shyn P, Tuncali K, Silverman S, Arellano R, Gee MS, Uppot RN. CT Texture Analysis and Machine Learning Improve Post-ablation Prognostication in Patients with Adrenal Metastases: A Proof of Concept. Cardiovasc Intervent Radiol. 2019 Dec; 42(12):1771-1776. PMID: 31489473.
    Citations:    
  2. Ratanaprasatporn L, Sainani N, Duda JB, Aghayev A, Tatli S, Silverman SG, Shyn PB. Imaging findings during and after percutaneous cryoablation of hepatic tumors. Abdom Radiol (NY). 2019 07; 44(7):2602-2626. PMID: 31004203.
    Citations:    
  3. Shyn PB. Is Image-guided Thermal Ablation Ready for Treatment of Stage 1 Non-Small Cell Lung Cancer? Radiology. 2018 12; 289(3):871-872. PMID: 30226452.
    Citations:    Fields:    
  4. Bhagavatula SK, Shyn PB. Image-Guided Renal Interventions. Urol Clin North Am. 2018 Aug; 45(3):351-363. PMID: 30031459.
    Citations:    Fields:    Translation:Humans
  5. Aguirre AJ, Nowak JA, Camarda ND, Moffitt RA, Ghazani AA, Hazar-Rethinam M, Raghavan S, Kim J, Brais LK, Ragon D, Welch MW, Reilly E, McCabe D, Marini L, Anderka K, Helvie K, Oliver N, Babic A, Da Silva A, Nadres B, Van Seventer EE, Shahzade HA, St Pierre JP, Burke KP, Clancy T, Cleary JM, Doyle LA, Jajoo K, McCleary NJ, Meyerhardt JA, Murphy JE, Ng K, Patel AK, Perez K, Rosenthal MH, Rubinson DA, Ryou M, Shapiro GI, Sicinska E, Silverman SG, Nagy RJ, Lanman RB, Knoerzer D, Welsch DJ, Yurgelun MB, Fuchs CS, Garraway LA, Getz G, Hornick JL, Johnson BE, Kulke MH, Mayer RJ, Miller JW, Shyn PB, Tuveson DA, Wagle N, Yeh JJ, Hahn WC, Corcoran RB, Carter SL, Wolpin BM. Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine. Cancer Discov. 2018 09; 8(9):1096-1111. PMID: 29903880.
    Citations: 3     Fields:    
  6. Shyn PB, Casadaban LC, Sainani NI, Sadow CA, Bunch PM, Levesque VM, Kim CK, Gerbaudo VH, Silverman SG. Intraprocedural Ablation Margin Assessment by Using Ammonia Perfusion PET during FDG PET/CT-guided Liver Tumor Ablation: A Pilot Study. Radiology. 2018 Jul; 288(1):138-145. PMID: 29613843.
    Citations:    Fields:    Translation:Humans
  7. Bhagavatula SK, Lane J, Shyn P. A Radiologist's View of Tumor Ablation in the Radiology Suite. Anesthesiol Clin. 2017 Dec; 35(4):617-626. PMID: 29101952.
    Citations:    Fields:    Translation:Humans
  8. Epelboym Y, Shyn PB, Chick JFB, Hamilton MJ, O'Connor SD, Silverman SG, Kim CK. Crohn Disease: FDG PET/CT Before and After Initial Dose of Anti-Tumor Necrosis Factor Therapy to Predict Long-term Response. Clin Nucl Med. 2017 Nov; 42(11):837-841. PMID: 28902728.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  9. Glazer DI, Tatli S, Shyn PB, Vangel MG, Tuncali K, Silverman SG. Percutaneous Image-Guided Cryoablation of Hepatic Tumors: Single-Center Experience With Intermediate to Long-Term Outcomes. AJR Am J Roentgenol. 2017 Dec; 209(6):1381-1389. PMID: 28952807.
    Citations:    Fields:    Translation:Humans
  10. Frenk NE, Daye D, Tuncali K, Arellano RS, Shyn PB, Silverman SG, Fintelmann FJ, Uppot RN. Local Control and Survival after Image-Guided Percutaneous Ablation of Adrenal Metastases. J Vasc Interv Radiol. 2018 02; 29(2):276-284. PMID: 28927661.
    Citations: 3     Fields:    Translation:Humans
  11. Young AS, Shyn PB, Johnson OW, Sainani NI, Nawfel RD, Silverman SG. Bending percutaneous drainage catheters to facilitate CT-guided insertion using curved trocar technique. Abdom Radiol (NY). 2017 08; 42(8):2160-2167. PMID: 28361226.
    Citations:    Fields:    Translation:Humans
  12. Shyn PB, O'Neill AC, Wiggins WF, Sainani NI, Tatli S, Tuncali K, Levesque VM, Silverman SG. Hepatobiliary phase MRI: impact on planning image-guided liver tumor ablations. Abdom Radiol (NY). 2017 08; 42(8):2168-2174. PMID: 28349225.
    Citations:    Fields:    Translation:Humans
  13. Khalilzadeh O, Baerlocher MO, Shyn PB, Connolly BL, Devane AM, Morris CS, Cohen AM, Midia M, Thornton RH, Gross K, Caplin DM, Aeron G, Misra S, Patel NH, Walker TG, Martinez-Salazar G, Silberzweig JE, Nikolic B. Proposal of a New Adverse Event Classification by the Society of Interventional Radiology Standards of Practice Committee. J Vasc Interv Radiol. 2017 Oct; 28(10):1432-1437.e3. PMID: 28757285.
    Citations:    Fields:    Translation:Humans
  14. Kis B, El-Haddad G, Sheth RA, Parikh NS, Ganguli S, Shyn PB, Choi J, Brown KT. Liver-Directed Therapies for Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma. Cancer Control. 2017 Jul-Sep; 24(3):1073274817729244. PMID: 28975829.
    Citations:    Fields:    Translation:Humans
  15. Kim H, Shyn PB, Wu L, Levesque VM, Khorasani R, Silverman SG. Wall suction-assisted image-guided thoracentesis: a safe alternative to evacuated bottles. Clin Radiol. 2017 Oct; 72(10):898.e1-898.e5. PMID: 28554579.
    Citations:    Fields:    Translation:Humans
  16. Epelboym Y, Shyn PB, Hosny A, Kelil T, Chick JFB, Chauhan NR, Ripley B, Nawfel RD, Scholz FJ. Use of a 3D-Printed Abdominal Compression Device to Facilitate CT Fluoroscopy-Guided Percutaneous Interventions. AJR Am J Roentgenol. 2017 Aug; 209(2):435-441. PMID: 28504546.
    Citations:    Fields:    Translation:Humans
  17. Mauri G, Nicosia L, Varano GM, Shyn P, Sartori S, Tombesi P, Di Vece F, Orsi F, Solbiati L. Unusual tumour ablations: report of difficult and interesting cases. Ecancermedicalscience. 2017; 11:733. PMID: 28487751.
    Citations: 2     
  18. Bhagavatula SK, Chick JF, Chauhan NR, Shyn PB. Artificial ascites and pneumoperitoneum to facilitate thermal ablation of liver tumors: a pictorial essay. Abdom Radiol (NY). 2017 02; 42(2):620-630. PMID: 27665483.
    Citations: 2     Fields:    Translation:Humans
  19. Bhagavatula SK, Shyn PB. Image-Guided Renal Interventions. Radiol Clin North Am. 2017 Mar; 55(2):359-371. PMID: 28126220.
    Citations: 1     Fields:    Translation:Humans
  20. Shyn PB, Tremblay-Paquet S, Palmer K, Tatli S, Tuncali K, Olubiyi OI, Hata N, Silverman SG. Breath-hold PET/CT-guided tumour ablation under general anaesthesia: accuracy of tumour image registration and projected ablation zone overlap. Clin Radiol. 2017 Mar; 72(3):223-229. PMID: 27889091.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  21. Guenette JP, Tuncali K, Himes N, Shyn PB, Lee TC. Percutaneous Image-Guided Cryoablation of Head and Neck Tumors for Local Control, Preservation of Functional Status, and Pain Relief. AJR Am J Roentgenol. 2017 Feb; 208(2):453-458. PMID: 27845860.
    Citations: 1     Fields:    Translation:Humans
  22. Burch EA, Shyn PB, Chick JF, Chauhan NR. Auditing an Online Self-reported Interventional Radiology Adverse Event Database for Compliance and Accuracy. J Am Coll Radiol. 2017 Apr; 14(4):494-498. PMID: 27815056.
    Citations:    Fields:    Translation:Humans
  23. Burch EA, Shyn PB. Developing an Interventional Radiology Online Quality Assurance Database. J Am Coll Radiol. 2017 03; 14(3):383-385. PMID: 28029584.
    Citations:    Fields:    Translation:Humans
  24. Shyn PB, Bird JR, Koch RM, Tatli S, Levesque VM, Catalano PJ, Silverman SG. Hepatic Microwave Ablation Zone Size: Correlation with Total Energy, Net Energy, and Manufacturer-Provided Chart Predictions. J Vasc Interv Radiol. 2016 Sep; 27(9):1389-1396. PMID: 27425001.
    Citations: 1     Fields:    Translation:Humans
  25. Kelil T, Shyn PB, Wu LE, Levesque VM, Kacher D, Khorasani R, Silverman SG. Wall suction-assisted image-guided therapeutic paracentesis: a safe and less expensive alternative to evacuated bottles. Abdom Radiol (NY). 2016 07; 41(7):1333-7. PMID: 27315094.
    Citations:    Fields:    Translation:Humans
  26. Sainani NI, Silverman SG, Tuna IS, Aghayev A, Shyn PB, Tuncali K, Kadiyala V, Tatli S. Incidence and clinical sequelae of portal and hepatic venous thrombosis following percutaneous cryoablation of liver tumors. Abdom Radiol (NY). 2016 05; 41(5):970-7. PMID: 27193794.
    Citations:    Fields:    Translation:Humans
  27. Fintelmann FJ, Tuncali K, Puchner S, Gervais DA, Thabet A, Shyn PB, Arellano RS, Tatli S, Mueller PR, Silverman SG, Uppot RN. Catecholamine Surge during Image-Guided Ablation of Adrenal Gland Metastases: Predictors, Consequences, and Recommendations for Management. J Vasc Interv Radiol. 2016 Mar; 27(3):395-402. PMID: 26724964.
    Citations: 4     Fields:    Translation:HumansCells
  28. Levesque VM, Shyn PB, Tuncali K, Tatli S, Nawfel RD, Olubiyi O, Silverman SG. Radiation dose during CT-guided percutaneous cryoablation of renal tumors: Effect of a dose reduction protocol. Eur J Radiol. 2015 Nov; 84(11):2218-21. PMID: 26223776.
    Citations:    Fields:    Translation:Humans
  29. Sarma A, Shyn PB, Vivian MA, Ng JM, Tuncali K, Lorch JH, Zaheer SN, Gordon MS, Silverman SG. Single-Session CT-Guided Percutaneous Microwave Ablation of Bilateral Adrenal Gland Hyperplasia Due to Ectopic ACTH Syndrome. Cardiovasc Intervent Radiol. 2015 Oct; 38(5):1335-8. PMID: 25762486.
    Citations:    Fields:    Translation:Humans
  30. Lemay A, Shyn PB, Foley R, Beutler SS, Silverman SG, Urman RD. A procedural sedation quality improvement audit form tool for interventional radiology. J Med Pract Manage. 2015 Mar-Apr; 30(6 Spec No):44-7. PMID: 26062317.
    Citations:    Fields:    Translation:Humans
  31. Hong TS, Bosch WR, Krishnan S, Kim TK, Mamon HJ, Shyn P, Ben-Josef E, Seong J, Haddock MG, Cheng JC, Feng MU, Stephans KL, Roberge D, Crane C, Dawson LA. Interobserver variability in target definition for hepatocellular carcinoma with and without portal vein thrombus: radiation therapy oncology group consensus guidelines. Int J Radiat Oncol Biol Phys. 2014 Jul 15; 89(4):804-13. PMID: 24969794.
    Citations: 8     Fields:    Translation:Humans
  32. Colak E, Tatli S, Shyn PB, Tuncali K, Silverman SG. CT-guided percutaneous cryoablation of central lung tumors. Diagn Interv Radiol. 2014 Jul-Aug; 20(4):316-22. PMID: 24808438.
    Citations: 2     Fields:    Translation:Humans
  33. Fairchild AH, Tatli S, Dunne RM, Shyn PB, Tuncali K, Silverman SG. Percutaneous cryoablation of hepatic tumors adjacent to the gallbladder: assessment of safety and effectiveness. J Vasc Interv Radiol. 2014 Sep; 25(9):1449-55. PMID: 24906627.
    Citations: 5     Fields:    Translation:Humans
  34. Shyn PB, Mauri G, Alencar RO, Tatli S, Shah SH, Morrison PR, Catalano PJ, Silverman SG. Percutaneous imaging-guided cryoablation of liver tumors: predicting local progression on 24-hour MRI. AJR Am J Roentgenol. 2014 Aug; 203(2):W181-91. PMID: 24555531.
    Citations: 11     Fields:    Translation:Humans
  35. Dunne RM, Shyn PB, Sung JC, Tatli S, Morrison PR, Catalano PJ, Silverman SG. Percutaneous treatment of hepatocellular carcinoma in patients with cirrhosis: a comparison of the safety of cryoablation and radiofrequency ablation. Eur J Radiol. 2014 Apr; 83(4):632-8. PMID: 24529593.
    Citations: 11     Fields:    Translation:Humans
  36. Shyn PB, Tatli S, Sahni VA, Sadow CA, Forgione K, Mauri G, Morrison PR, Catalano PJ, Silverman SG. PET/CT-guided percutaneous liver mass biopsies and ablations: targeting accuracy of a single 20 s breath-hold PET acquisition. Clin Radiol. 2014 Apr; 69(4):410-5. PMID: 24411824.
    Citations: 10     Fields:    Translation:Humans
  37. Sainani NI, Tatli S, Anthony SG, Shyn PB, Tuncali K, Silverman SG. Successful percutaneous radiologic management of renal cell carcinoma tumor seeding caused by percutaneous biopsy performed before ablation. J Vasc Interv Radiol. 2013 Sep; 24(9):1404-8. PMID: 23973027.
    Citations: 3     Fields:    Translation:Humans
  38. Shyn PB. Interventional positron emission tomography/computed tomography: state-of-the-art. Tech Vasc Interv Radiol. 2013 Sep; 16(3):182-90. PMID: 23993081.
    Citations: 6     Fields:    Translation:Humans
  39. Sainani NI, Arellano RS, Shyn PB, Gervais DA, Mueller PR, Silverman SG. The challenging image-guided abdominal mass biopsy: established and emerging techniques 'if you can see it, you can biopsy it'. Abdom Imaging. 2013 Aug; 38(4):672-96. PMID: 23381506.
    Citations: 8     Fields:    Translation:Humans
  40. Wasser EJ, Shyn PB, Riveros-Angel M, Sadow CA, Steele GS, Silverman SG. Renal cell carcinoma containing abundant non-calcified fat. Abdom Imaging. 2013 Jun; 38(3):598-602. PMID: 22699696.
    Citations: 3     Fields:    Translation:Humans
  41. Javery O, Shyn P, Mortele K. FDG PET or PET/CT in patients with pancreatic cancer: when does it add to diagnostic CT or MRI? Clin Imaging. 2013 Mar-Apr; 37(2):295-301. PMID: 23465982.
    Citations: 4     Fields:    Translation:Humans
  42. Shinagare AB, Shyn PB, Sadow CA, Wasser EJ, Catalano P. Incidence, appropriateness, and consequences of recommendations for additional imaging tests in oncological PET/CT reports. Clin Radiol. 2013 Feb; 68(2):155-61. PMID: 22892243.
    Citations:    Fields:    Translation:Humans
  43. Liszewski MC, Sahni VA, Shyn PB, Friedman S, Hornick JL, Erturk SM, Mortele KJ. Multidetector-row computed tomography enterographic assessment of the ileal-anal pouch: descriptive radiologic analysis with endoscopic and pathologic correlation. J Comput Assist Tomogr. 2012 Jul-Aug; 36(4):394-9. PMID: 22805666.
    Citations: 1     Fields:    Translation:Humans
  44. Shyn PB. 18F-FDG positron emission tomography: potential utility in the assessment of Crohn's disease. Abdom Imaging. 2012 Jun; 37(3):377-86. PMID: 21833729.
    Citations: 5     Fields:    Translation:Humans
  45. Fernandes DD, Shyn PB, Silverman SG. Gallbladder needle decompression during radiofrequency ablation of an adjacent liver tumour. Can Assoc Radiol J. 2012 Aug; 63(3 Suppl):S37-40. PMID: 22280789.
    Citations: 2     Fields:    Translation:Humans
  46. Shyn PB, Oliva MR, Shah SH, Tatli S, Catalano PJ, Silverman SG. MRI contrast enhancement of malignant liver tumours following successful cryoablation. Eur Radiol. 2012 Feb; 22(2):398-403. PMID: 21898153.
    Citations: 3     Fields:    Translation:Humans
  47. Shyn PB, Tatli S, Sainani NI, Morrison PR, Habbab F, Catalano P, Silverman SG. Minimizing image misregistration during PET/CT-guided percutaneous interventions with monitored breath-hold PET and CT acquisitions. J Vasc Interv Radiol. 2011 Sep; 22(9):1287-92. PMID: 21778067.
    Citations: 3     Fields:    Translation:Humans
  48. Park BK, Morrison PR, Tatli S, Govindarajulu U, Tuncali K, Judy P, Shyn PB, Silverman SG. Estimated effective dose of CT-guided percutaneous cryoablation of liver tumors. Eur J Radiol. 2012 Aug; 81(8):1702-6. PMID: 21645981.
    Citations: 2     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  49. Tatli S, Gerbaudo VH, Feeley CM, Shyn PB, Tuncali K, Silverman SG. PET/CT-guided percutaneous biopsy of abdominal masses: initial experience. J Vasc Interv Radiol. 2011 Apr; 22(4):507-14. PMID: 21367619.
    Citations: 16     Fields:    Translation:Humans
  50. Sainani NI, Shyn PB, Tatli S, Morrison PR, Tuncali K, Silverman SG. PET/CT-guided radiofrequency and cryoablation: is tumor fluorine-18 fluorodeoxyglucose activity dissipated by thermal ablation? J Vasc Interv Radiol. 2011 Mar; 22(3):354-60. PMID: 21353987.
    Citations: 4     Fields:    Translation:Humans
  51. Sahni VA, Shyn PB. Predicting the need for surgery in obstructive Crohn's disease: how hot is PET/CT? Inflamm Bowel Dis. 2010 Dec; 16(12):2182-3. PMID: 20848519.
    Citations:    Fields:    
  52. Shyn PB, Mortele KJ, Britz-Cunningham SH, Friedman S, Odze RD, Burakoff R, Goldberg JE, Erturk M, Silverman SG. Low-dose 18F-FDG PET/CT enterography: improving on CT enterography assessment of patients with Crohn disease. J Nucl Med. 2010 Dec; 51(12):1841-8. PMID: 21078803.
    Citations: 8     Fields:    Translation:Humans
  53. Elhawary H, Oguro S, Tuncali K, Morrison PR, Tatli S, Shyn PB, Silverman SG, Hata N. Multimodality non-rigid image registration for planning, targeting and monitoring during CT-guided percutaneous liver tumor cryoablation. Acad Radiol. 2010 Nov; 17(11):1334-44. PMID: 20817574.
    Citations: 12     Fields:    Translation:Humans
  54. Tatli S, Gerbaudo VH, Mamede M, Tuncali K, Shyn PB, Silverman SG. Abdominal masses sampled at PET/CT-guided percutaneous biopsy: initial experience with registration of prior PET/CT images. Radiology. 2010 Jul; 256(1):305-11. PMID: 20574103.
    Citations: 13     Fields:    Translation:Humans
  55. Shyn PB, Madan R, Wu C, Erturk SM, Silverman SG. PET/CT pattern analysis for surgical staple line recurrence in patients with colorectal cancer. AJR Am J Roentgenol. 2010 Feb; 194(2):414-21. PMID: 20093604.
    Citations: 6     Fields:    Translation:Humans
  56. Oei TN, Shyn PB, Govindarajulu U, Flint R. Diagnostic medical radiation dose in patients after laparoscopic bariatric surgery. Obes Surg. 2010 May; 20(5):569-73. PMID: 19779760.
    Citations: 4     Fields:    Translation:Humans
  57. Schenker MP, Martin R, Shyn PB, Baum RA. Interventional radiology and anesthesia. Anesthesiol Clin. 2009 Mar; 27(1):87-94. PMID: 19361770.
    Citations:    Fields:    Translation:Humans
  58. Elhawary H, Oguro S, Tuncali K, Morrison PR, Shyn PB, Tatli S, Silverman SG, Hat N. Intra-operative multimodal non-rigid registration of the liver for navigated tumor ablation. Med Image Comput Comput Assist Interv. 2009; 12(Pt 1):837-44. PMID: 20426066.
    Citations: 3     Fields:    Translation:Humans
  59. Shyn PB. Diagnostic medical radiation in IBD. Inflamm Bowel Dis. 2008 Oct; 14(10):1455-6. PMID: 18398897.
    Citations:    Fields:    
  60. Shyn PB. Protocol considerations for thoracic positron emission tomography-computed tomography. Semin Ultrasound CT MR. 2008 Aug; 29(4):242-50. PMID: 18795491.
    Citations: 1     Fields:    Translation:Humans
  61. Thoeni RF, Mueller-Lisse UG, Chan R, Do NK, Shyn PB. Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity. Radiology. 2000 Feb; 214(2):483-90. PMID: 10671597.
    Citations: 32     Fields:    Translation:Humans
  62. Shyn PB, Goldberg HI. Abdominal CT following liver transplantation. Gastrointest Radiol. 1992; 17(3):231-6. PMID: 1612309.
    Citations: 1     Fields:    Translation:Humans
  63. Shyn PB, Bell KA. Transient cortical blindness following cerebral angiography. J La State Med Soc. 1989 Nov; 141(11):35-7. PMID: 2592849.
    Citations: 3     Fields:    Translation:Humans
  64. Bluth EI, Shyn PB, Sullivan MA, Merritt CR. Doppler color flow imaging of carotid artery dissection. J Ultrasound Med. 1989 Mar; 8(3):149-53. PMID: 2657094.
    Citations: 3     Fields:    Translation:Humans
  65. Shyn PB, Campbell GA, Guinto FC, Crofford MJ. Primary intracranial ependymoblastoma presenting as spinal cord compression due to metastasis. Childs Nerv Syst. 1986; 2(6):323-5. PMID: 3829033.
    Citations: 2     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.