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profilePaul B. Shyn, M.D.

TitleAssistant Professor of Radiology
InstitutionBrigham and Women's Hospital
DepartmentRadiology
AddressBrigham and Womens Hospital
Dept. of Radiology
75 Francis St
Boston MA 02115
Phone617/732-6304
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Collapse Biography 
Collapse awards and honors
2008Academic Transition Grant
2008Wylie J. Dodds Research Award
2012George Marina Memorial Radiology Residency Teaching Award

Collapse Overview 
Collapse overview
Primary Interests:

PET/CT imaging of malignancy and inflammation

Cross-sectional imaging-guided interventional procedures including tumor ablation

PET/CT-guided interventional radiology procedures


Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Epelboym Y, Shyn PB, Chick JFB, Hamilton MJ, O'Connor SD, Silverman SG, Kim CK. Crohn Disease: FDG PET/CT Before and After Initial Dose of Anti-Tumor Necrosis Factor Therapy to Predict Long-term Response. Clin Nucl Med. 2017 Nov; 42(11):837-841. PMID: 28902728.
    View in: PubMed
  2. Glazer DI, Tatli S, Shyn PB, Vangel MG, Tuncali K, Silverman SG. Percutaneous Image-Guided Cryoablation of Hepatic Tumors: Single-Center Experience With Intermediate to Long-Term Outcomes. AJR Am J Roentgenol. 2017 Sep 27; 1-9. PMID: 28952807.
    View in: PubMed
  3. Frenk NE, Daye D, Tuncali K, Arellano RS, Shyn PB, Silverman SG, Fintelmann FJ, Uppot RN. Local Control and Survival after Image-Guided Percutaneous Ablation of Adrenal Metastases. J Vasc Interv Radiol. 2017 Sep 16. PMID: 28927661.
    View in: PubMed
  4. Young AS, Shyn PB, Johnson OW, Sainani NI, Nawfel RD, Silverman SG. Bending percutaneous drainage catheters to facilitate CT-guided insertion using curved trocar technique. Abdom Radiol (NY). 2017 Aug; 42(8):2160-2167. PMID: 28361226.
    View in: PubMed
  5. Shyn PB, O'Neill AC, Wiggins WF, Sainani NI, Tatli S, Tuncali K, Levesque VM, Silverman SG. Hepatobiliary phase MRI: impact on planning image-guided liver tumor ablations. Abdom Radiol (NY). 2017 Aug; 42(8):2168-2174. PMID: 28349225.
    View in: PubMed
  6. Khalilzadeh O, Baerlocher MO, Shyn PB, Connolly BL, Devane AM, Morris CS, Cohen AM, Midia M, Thornton RH, Gross K, Caplin DM, Aeron G, Misra S, Patel NH, Walker TG, Martinez-Salazar G, Silberzweig JE, Nikolic B. Proposal of a New Adverse Event Classification by the Society of Interventional Radiology Standards of Practice Committee. J Vasc Interv Radiol. 2017 Oct; 28(10):1432-1437.e3. PMID: 28757285.
    View in: PubMed
  7. Kis B, El-Haddad G, Sheth RA, Parikh NS, Ganguli S, Shyn PB, Choi J, Brown KT. Liver-Directed Therapies for Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma. Cancer Control. 2017 Jul-Sep; 24(3):1073274817729244. PMID: 28975829.
    View in: PubMed
  8. Kim H, Shyn PB, Wu L, Levesque VM, Khorasani R, Silverman SG. Wall suction-assisted image-guided thoracentesis: a safe alternative to evacuated bottles. Clin Radiol. 2017 Oct; 72(10):898.e1-898.e5. PMID: 28554579.
    View in: PubMed
  9. Epelboym Y, Shyn PB, Hosny A, Kelil T, Chick JFB, Chauhan NR, Ripley B, Nawfel RD, Scholz FJ. Use of a 3D-Printed Abdominal Compression Device to Facilitate CT Fluoroscopy-Guided Percutaneous Interventions. AJR Am J Roentgenol. 2017 Aug; 209(2):435-441. PMID: 28504546.
    View in: PubMed
  10. Mauri G, Nicosia L, Varano GM, Shyn P, Sartori S, Tombesi P, Di Vece F, Orsi F, Solbiati L. Unusual tumour ablations: report of difficult and interesting cases. Ecancermedicalscience. 2017; 11:733. PMID: 28487751.
    View in: PubMed
  11. Bhagavatula SK, Chick JF, Chauhan NR, Shyn PB. Artificial ascites and pneumoperitoneum to facilitate thermal ablation of liver tumors: a pictorial essay. Abdom Radiol (NY). 2017 Feb; 42(2):620-630. PMID: 27665483.
    View in: PubMed
  12. Bhagavatula SK, Shyn PB. Image-Guided Renal Interventions. Radiol Clin North Am. 2017 Mar; 55(2):359-371. PMID: 28126220.
    View in: PubMed
  13. Shyn PB, Tremblay-Paquet S, Palmer K, Tatli S, Tuncali K, Olubiyi OI, Hata N, Silverman SG. Breath-hold PET/CT-guided tumour ablation under general anaesthesia: accuracy of tumour image registration and projected ablation zone overlap. Clin Radiol. 2017 Mar; 72(3):223-229. PMID: 27889091.
    View in: PubMed
  14. Guenette JP, Tuncali K, Himes N, Shyn PB, Lee TC. Percutaneous Image-Guided Cryoablation of Head and Neck Tumors for Local Control, Preservation of Functional Status, and Pain Relief. AJR Am J Roentgenol. 2017 Feb; 208(2):453-458. PMID: 27845860.
    View in: PubMed
  15. Burch EA, Shyn PB, Chick JF, Chauhan NR. Auditing an Online Self-reported Interventional Radiology Adverse Event Database for Compliance and Accuracy. J Am Coll Radiol. 2017 Apr; 14(4):494-498. PMID: 27815056.
    View in: PubMed
  16. Burch EA, Shyn PB. Developing an Interventional Radiology Online Quality Assurance Database. J Am Coll Radiol. 2017 03; 14(3):383-385. PMID: 28029584.
    View in: PubMed
  17. Shyn PB, Bird JR, Koch RM, Tatli S, Levesque VM, Catalano PJ, Silverman SG. Hepatic Microwave Ablation Zone Size: Correlation with Total Energy, Net Energy, and Manufacturer-Provided Chart Predictions. J Vasc Interv Radiol. 2016 Sep; 27(9):1389-1396. PMID: 27425001.
    View in: PubMed
  18. Kelil T, Shyn PB, Wu LE, Levesque VM, Kacher D, Khorasani R, Silverman SG. Wall suction-assisted image-guided therapeutic paracentesis: a safe and less expensive alternative to evacuated bottles. Abdom Radiol (NY). 2016 Jul; 41(7):1333-7. PMID: 27315094.
    View in: PubMed
  19. Sainani NI, Silverman SG, Tuna IS, Aghayev A, Shyn PB, Tuncali K, Kadiyala V, Tatli S. Incidence and clinical sequelae of portal and hepatic venous thrombosis following percutaneous cryoablation of liver tumors. Abdom Radiol (NY). 2016 05; 41(5):970-7. PMID: 27193794.
    View in: PubMed
  20. Fintelmann FJ, Tuncali K, Puchner S, Gervais DA, Thabet A, Shyn PB, Arellano RS, Tatli S, Mueller PR, Silverman SG, Uppot RN. Catecholamine Surge during Image-Guided Ablation of Adrenal Gland Metastases: Predictors, Consequences, and Recommendations for Management. J Vasc Interv Radiol. 2016 Mar; 27(3):395-402. PMID: 26724964.
    View in: PubMed
  21. Levesque VM, Shyn PB, Tuncali K, Tatli S, Nawfel RD, Olubiyi O, Silverman SG. Radiation dose during CT-guided percutaneous cryoablation of renal tumors: Effect of a dose reduction protocol. Eur J Radiol. 2015 Nov; 84(11):2218-21. PMID: 26223776.
    View in: PubMed
  22. Sarma A, Shyn PB, Vivian MA, Ng JM, Tuncali K, Lorch JH, Zaheer SN, Gordon MS, Silverman SG. Single-Session CT-Guided Percutaneous Microwave Ablation of Bilateral Adrenal Gland Hyperplasia Due to Ectopic ACTH Syndrome. Cardiovasc Intervent Radiol. 2015 Oct; 38(5):1335-8. PMID: 25762486.
    View in: PubMed
  23. Lemay A, Shyn PB, Foley R, Beutler SS, Silverman SG, Urman RD. A procedural sedation quality improvement audit form tool for interventional radiology. J Med Pract Manage. 2015 Mar-Apr; 30(6 Spec No):44-7. PMID: 26062317.
    View in: PubMed
  24. Hong TS, Bosch WR, Krishnan S, Kim TK, Mamon HJ, Shyn P, Ben-Josef E, Seong J, Haddock MG, Cheng JC, Feng MU, Stephans KL, Roberge D, Crane C, Dawson LA. Interobserver variability in target definition for hepatocellular carcinoma with and without portal vein thrombus: radiation therapy oncology group consensus guidelines. Int J Radiat Oncol Biol Phys. 2014 Jul 15; 89(4):804-13. PMID: 24969794; PMCID: PMC4285340.
  25. Colak E, Tatli S, Shyn PB, Tuncali K, Silverman SG. CT-guided percutaneous cryoablation of central lung tumors. Diagn Interv Radiol. 2014 Jul-Aug; 20(4):316-22. PMID: 24808438; PMCID: PMC4463273.
  26. Fairchild AH, Tatli S, Dunne RM, Shyn PB, Tuncali K, Silverman SG. Percutaneous cryoablation of hepatic tumors adjacent to the gallbladder: assessment of safety and effectiveness. J Vasc Interv Radiol. 2014 Sep; 25(9):1449-55. PMID: 24906627.
    View in: PubMed
  27. Shyn PB, Mauri G, Alencar RO, Tatli S, Shah SH, Morrison PR, Catalano PJ, Silverman SG. Percutaneous imaging-guided cryoablation of liver tumors: predicting local progression on 24-hour MRI. AJR Am J Roentgenol. 2014 Aug; 203(2):W181-91. PMID: 24555531.
    View in: PubMed
  28. Dunne RM, Shyn PB, Sung JC, Tatli S, Morrison PR, Catalano PJ, Silverman SG. Percutaneous treatment of hepatocellular carcinoma in patients with cirrhosis: a comparison of the safety of cryoablation and radiofrequency ablation. Eur J Radiol. 2014 Apr; 83(4):632-8. PMID: 24529593.
    View in: PubMed
  29. Shyn PB, Tatli S, Sahni VA, Sadow CA, Forgione K, Mauri G, Morrison PR, Catalano PJ, Silverman SG. PET/CT-guided percutaneous liver mass biopsies and ablations: targeting accuracy of a single 20 s breath-hold PET acquisition. Clin Radiol. 2014 Apr; 69(4):410-5. PMID: 24411824.
    View in: PubMed
  30. Sainani NI, Tatli S, Anthony SG, Shyn PB, Tuncali K, Silverman SG. Successful percutaneous radiologic management of renal cell carcinoma tumor seeding caused by percutaneous biopsy performed before ablation. J Vasc Interv Radiol. 2013 Sep; 24(9):1404-8. PMID: 23973027.
    View in: PubMed
  31. Shyn PB. Interventional positron emission tomography/computed tomography: state-of-the-art. Tech Vasc Interv Radiol. 2013 Sep; 16(3):182-90. PMID: 23993081.
    View in: PubMed
  32. Sainani NI, Arellano RS, Shyn PB, Gervais DA, Mueller PR, Silverman SG. The challenging image-guided abdominal mass biopsy: established and emerging techniques 'if you can see it, you can biopsy it'. Abdom Imaging. 2013 Aug; 38(4):672-96. PMID: 23381506.
    View in: PubMed
  33. Wasser EJ, Shyn PB, Riveros-Angel M, Sadow CA, Steele GS, Silverman SG. Renal cell carcinoma containing abundant non-calcified fat. Abdom Imaging. 2013 Jun; 38(3):598-602. PMID: 22699696.
    View in: PubMed
  34. Javery O, Shyn P, Mortele K. FDG PET or PET/CT in patients with pancreatic cancer: when does it add to diagnostic CT or MRI? Clin Imaging. 2013 Mar-Apr; 37(2):295-301. PMID: 23465982.
    View in: PubMed
  35. Shinagare AB, Shyn PB, Sadow CA, Wasser EJ, Catalano P. Incidence, appropriateness, and consequences of recommendations for additional imaging tests in oncological PET/CT reports. Clin Radiol. 2013 Feb; 68(2):155-61. PMID: 22892243.
    View in: PubMed
  36. Liszewski MC, Sahni VA, Shyn PB, Friedman S, Hornick JL, Erturk SM, Mortele KJ. Multidetector-row computed tomography enterographic assessment of the ileal-anal pouch: descriptive radiologic analysis with endoscopic and pathologic correlation. J Comput Assist Tomogr. 2012 Jul-Aug; 36(4):394-9. PMID: 22805666.
    View in: PubMed
  37. Shyn PB. 18F-FDG positron emission tomography: potential utility in the assessment of Crohn's disease. Abdom Imaging. 2012 Jun; 37(3):377-86. PMID: 21833729.
    View in: PubMed
  38. Fernandes DD, Shyn PB, Silverman SG. Gallbladder needle decompression during radiofrequency ablation of an adjacent liver tumour. Can Assoc Radiol J. 2012 Aug; 63(3 Suppl):S37-40. PMID: 22280789.
    View in: PubMed
  39. Shyn PB, Oliva MR, Shah SH, Tatli S, Catalano PJ, Silverman SG. MRI contrast enhancement of malignant liver tumours following successful cryoablation. Eur Radiol. 2012 Feb; 22(2):398-403. PMID: 21898153.
    View in: PubMed
  40. Shyn PB, Tatli S, Sainani NI, Morrison PR, Habbab F, Catalano P, Silverman SG. Minimizing image misregistration during PET/CT-guided percutaneous interventions with monitored breath-hold PET and CT acquisitions. J Vasc Interv Radiol. 2011 Sep; 22(9):1287-92. PMID: 21778067.
    View in: PubMed
  41. Park BK, Morrison PR, Tatli S, Govindarajulu U, Tuncali K, Judy P, Shyn PB, Silverman SG. Estimated effective dose of CT-guided percutaneous cryoablation of liver tumors. Eur J Radiol. 2012 Aug; 81(8):1702-6. PMID: 21645981; PMCID: PMC3782862.
  42. Tatli S, Gerbaudo VH, Feeley CM, Shyn PB, Tuncali K, Silverman SG. PET/CT-guided percutaneous biopsy of abdominal masses: initial experience. J Vasc Interv Radiol. 2011 Apr; 22(4):507-14. PMID: 21367619.
    View in: PubMed
  43. Sainani NI, Shyn PB, Tatli S, Morrison PR, Tuncali K, Silverman SG. PET/CT-guided radiofrequency and cryoablation: is tumor fluorine-18 fluorodeoxyglucose activity dissipated by thermal ablation? J Vasc Interv Radiol. 2011 Mar; 22(3):354-60. PMID: 21353987.
    View in: PubMed
  44. Sahni VA, Shyn PB. Predicting the need for surgery in obstructive Crohn's disease: how hot is PET/CT? Inflamm Bowel Dis. 2010 Dec; 16(12):2182-3. PMID: 20848519.
    View in: PubMed
  45. Shyn PB, Mortele KJ, Britz-Cunningham SH, Friedman S, Odze RD, Burakoff R, Goldberg JE, Erturk M, Silverman SG. Low-dose 18F-FDG PET/CT enterography: improving on CT enterography assessment of patients with Crohn disease. J Nucl Med. 2010 Dec; 51(12):1841-8. PMID: 21078803.
    View in: PubMed
  46. Elhawary H, Oguro S, Tuncali K, Morrison PR, Tatli S, Shyn PB, Silverman SG, Hata N. Multimodality non-rigid image registration for planning, targeting and monitoring during CT-guided percutaneous liver tumor cryoablation. Acad Radiol. 2010 Nov; 17(11):1334-44. PMID: 20817574; PMCID: PMC2952665.
  47. Tatli S, Gerbaudo VH, Mamede M, Tuncali K, Shyn PB, Silverman SG. Abdominal masses sampled at PET/CT-guided percutaneous biopsy: initial experience with registration of prior PET/CT images. Radiology. 2010 Jul; 256(1):305-11. PMID: 20574103.
    View in: PubMed
  48. Shyn PB, Madan R, Wu C, Erturk SM, Silverman SG. PET/CT pattern analysis for surgical staple line recurrence in patients with colorectal cancer. AJR Am J Roentgenol. 2010 Feb; 194(2):414-21. PMID: 20093604.
    View in: PubMed
  49. Oei TN, Shyn PB, Govindarajulu U, Flint R. Diagnostic medical radiation dose in patients after laparoscopic bariatric surgery. Obes Surg. 2010 May; 20(5):569-73. PMID: 19779760.
    View in: PubMed
  50. Schenker MP, Martin R, Shyn PB, Baum RA. Interventional radiology and anesthesia. Anesthesiol Clin. 2009 Mar; 27(1):87-94. PMID: 19361770.
    View in: PubMed
  51. Elhawary H, Oguro S, Tuncali K, Morrison PR, Shyn PB, Tatli S, Silverman SG, Hat N. Intra-operative multimodal non-rigid registration of the liver for navigated tumor ablation. Med Image Comput Comput Assist Interv. 2009; 12(Pt 1):837-44. PMID: 20426066.
    View in: PubMed
  52. Shyn PB. Diagnostic medical radiation in IBD. Inflamm Bowel Dis. 2008 Oct; 14(10):1455-6. PMID: 18398897.
    View in: PubMed
  53. Shyn PB. Protocol considerations for thoracic positron emission tomography-computed tomography. Semin Ultrasound CT MR. 2008 Aug; 29(4):242-50. PMID: 18795491.
    View in: PubMed
  54. Thoeni RF, Mueller-Lisse UG, Chan R, Do NK, Shyn PB. Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity. Radiology. 2000 Feb; 214(2):483-90. PMID: 10671597.
    View in: PubMed
  55. Shyn PB, Goldberg HI. Abdominal CT following liver transplantation. Gastrointest Radiol. 1992; 17(3):231-6. PMID: 1612309.
    View in: PubMed
  56. Shyn PB, Bell KA. Transient cortical blindness following cerebral angiography. J La State Med Soc. 1989 Nov; 141(11):35-7. PMID: 2592849.
    View in: PubMed
  57. Bluth EI, Shyn PB, Sullivan MA, Merritt CR. Doppler color flow imaging of carotid artery dissection. J Ultrasound Med. 1989 Mar; 8(3):149-53. PMID: 2657094.
    View in: PubMed
  58. Shyn PB, Campbell GA, Guinto FC, Crofford MJ. Primary intracranial ependymoblastoma presenting as spinal cord compression due to metastasis. Childs Nerv Syst. 1986; 2(6):323-5. PMID: 3829033.
    View in: PubMed
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