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Gil Alterovitz, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM118467 (ALTEROVITZ, GIL) Sep 1, 2016 - Aug 31, 2021
    NIH/NIGMS
    Towards a generalizable drug discovery framework based on intrinsically disordered regions
    Role: Principal Investigator
  2. R01HG004836 (ALTEROVITZ, GIL) Sep 30, 2009 - Aug 31, 2013
    NIH/NHGRI
    Automated Integration of Biomedical Knowledge
    Role: Principal Investigator
  3. R00LM009826 (ALTEROVITZ, GIL) Sep 30, 2008 - Sep 29, 2014
    NIH/NLM
    A Holistic Approach to Information Processing for Biomedical Networks
    Role: Principal Investigator
  4. K99LM009826 (ALTEROVITZ, GIL) Sep 30, 2008 - Sep 29, 2010
    NIH/NLM
    A Holistic Approach to Information Processing for Biomedical Networks
    Role: Principal Investigator
  5. R21DA025168 (ALTEROVITZ, GIL) May 1, 2008 - Apr 30, 2013
    NIH/NIDA
    Beyond Association: Predictive Modeling of Nicotine Dependance
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Liao M, Tong T, Zong Y, Zhou X, Cheng L, Huang R, Ren B, Alterovitz G. Application of Omics and Bioinformatics Tools in Streptococcus Research. Curr Issues Mol Biol. 2019 Jun 05; 32:327-376. PMID: 31166175.
    Citations:    
  2. Alterovitz G, Dean D, Goble C, Crusoe MR, Soiland-Reyes S, Bell A, Hayes A, Suresh A, Purkayastha A, King CH, Taylor D, Johanson E, Thompson EE, Donaldson E, Morizono H, Tsang H, Vora JK, Goecks J, Yao J, Almeida JS, Keeney J, Addepalli K, Krampis K, Smith KM, Guo L, Walderhaug M, Schito M, Ezewudo M, Guimera N, Walsh P, Kahsay R, Gottipati S, Rodwell TC, Bloom T, Lai Y, Simonyan V, Mazumder R. Enabling precision medicine via standard communication of HTS provenance, analysis, and results. PLoS Biol. 2018 12; 16(12):e3000099. PMID: 30596645.
    Citations:    Fields:    
  3. Warner JL, Prasad I, Bennett M, Arniella M, Beeghly-Fadiel A, Mandl KD, Alterovitz G. SMART Cancer Navigator: A Framework for Implementing ASCO Workshop Recommendations to Enable Precision Cancer Medicine. JCO Precis Oncol. 2018; 2018. PMID: 30238071.
    Citations:    
  4. Zhou Y, Yang H, Zhou X, Luo H, Tang F, Yang J, Alterovitz G, Cheng L, Ren B. Lovastatin synergizes with itraconazole against planktonic cells and biofilms of Candida albicans through the regulation on ergosterol biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jun; 102(12):5255-5264. PMID: 29691631.
    Citations:    Fields:    Translation:Animals
  5. Warner JL, Yang PC, Alterovitz G. Overcoming the Straw Man Effect in Oncology: Visualization and Ranking of Chemotherapy Regimens Using an Information Theoretic Approach. JCO Clin Cancer Inform. 2017 11; 1:1-9. PMID: 30657401.
    Citations:    
  6. Barlow SM, Maron JL, Alterovitz G, Song D, Wilson BJ, Jegatheesan P, Govindaswami B, Lee J, Rosner AO. Somatosensory Modulation of Salivary Gene Expression and Oral Feeding in Preterm Infants: Randomized Controlled Trial. JMIR Res Protoc. 2017 Jun 14; 6(6):e113. PMID: 28615158.
    Citations: 1     
  7. Yang J, Yu S, Gong B, An N, Alterovitz G. Biobrick chain recommendations for genetic circuit design. Comput Biol Med. 2017 07 01; 86:31-39. PMID: 28499216.
    Citations:    Fields:    
  8. Zollanvari A, Alterovitz G. SNP by SNP by environment interaction network of alcoholism. BMC Syst Biol. 2017 03 14; 11(Suppl 3):19. PMID: 28361705.
    Citations: 2     Fields:    Translation:Humans
  9. Yang J, Wang H, Ding H, An N, Alterovitz G. Nonlinear dimensionality reduction methods for synthetic biology biobricks' visualization. BMC Bioinformatics. 2017 Jan 19; 18(1):47. PMID: 28103789.
    Citations:    Fields:    
  10. Wang A, An N, Yang J, Chen G, Li L, Alterovitz G. Wrapper-based gene selection with Markov blanket. Comput Biol Med. 2017 02 01; 81:11-23. PMID: 28006702.
    Citations: 1     Fields:    Translation:Humans
  11. Yang Y, Chen S, Yang F, Zhang L, Alterovitz G, Zhu H, Xuan J, Yang X, Luo H, Mu J, He L, Luo X, Xing Q. HLA-B*51:01 is strongly associated with clindamycin-related cutaneous adverse drug reactions. Pharmacogenomics J. 2017 12; 17(6):501-505. PMID: 27527109.
    Citations:    Fields:    Translation:HumansCells
  12. Kapur A, Marwah K, Alterovitz G. Gene expression prediction using low-rank matrix completion. BMC Bioinformatics. 2016 Jun 17; 17(1):243. PMID: 27317252.
    Citations: 2     Fields:    Translation:HumansCells
  13. Warner JL, Rioth MJ, Mandl KD, Mandel JC, Kreda DA, Kohane IS, Carbone D, Oreto R, Wang L, Zhu S, Yao H, Alterovitz G. SMART precision cancer medicine: a FHIR-based app to provide genomic information at the point of care. J Am Med Inform Assoc. 2016 07; 23(4):701-10. PMID: 27018265.
    Citations: 8     Fields:    Translation:Humans
  14. Warner JL, Zhang P, Liu J, Alterovitz G. Classification of hospital acquired complications using temporal clinical information from a large electronic health record. J Biomed Inform. 2016 Feb; 59:209-17. PMID: 26707449.
    Citations: 2     Fields:    Translation:Humans
  15. Lawler M, Siu LL, Rehm HL, Chanock SJ, Alterovitz G, Burn J, Calvo F, Lacombe D, Teh BT, North KN, Sawyers CL. All the World's a Stage: Facilitating Discovery Science and Improved Cancer Care through the Global Alliance for Genomics and Health. Cancer Discov. 2015 Nov; 5(11):1133-6. PMID: 26526696.
    Citations: 14     Fields:    Translation:Humans
  16. Alterovitz G, Warner J, Zhang P, Chen Y, Ullman-Cullere M, Kreda D, Kohane IS. SMART on FHIR Genomics: facilitating standardized clinico-genomic apps. J Am Med Inform Assoc. 2015 Nov; 22(6):1173-8. PMID: 26198304.
    Citations: 21     Fields:    Translation:Humans
  17. Wang A, An N, Chen G, Li L, Alterovitz G. Improving PLS-RFE based gene selection for microarray data classification. Comput Biol Med. 2015 Jul; 62:14-24. PMID: 25912984.
    Citations:    Fields:    
  18. Maron JL, Hwang JS, Pathak S, Ruthazer R, Russell RL, Alterovitz G. Computational gene expression modeling identifies salivary biomarker analysis that predict oral feeding readiness in the newborn. J Pediatr. 2015 Feb; 166(2):282-8.e5. PMID: 25620512.
    Citations: 6     Fields:    Translation:Humans
  19. Warner JL, Denny JC, Kreda DA, Alterovitz G. Seeing the forest through the trees: uncovering phenomic complexity through interactive network visualization. J Am Med Inform Assoc. 2015 Mar; 22(2):324-9. PMID: 25336590.
    Citations: 6     Fields:    
  20. Li Y, Wei Y, Li B, Alterovitz G. Modified Anderson-Darling test-based target detector in non-homogenous environments. Sensors (Basel). 2014 Aug 29; 14(9):16046-61. PMID: 25177800.
    Citations:    Fields:    
  21. Gao M, Warner J, Yang P, Alterovitz G. On the Bayesian Derivation of a Treatment-based Cancer Ontology. AMIA Jt Summits Transl Sci Proc. 2014; 2014:209-17. PMID: 25954588.
    Citations:    
  22. Villa A, Zollanvari A, Alterovitz G, Cagetti MG, Strohmenger L, Abati S. Prevalence of halitosis in children considering oral hygiene, gender and age. Int J Dent Hyg. 2014 Aug; 12(3):208-12. PMID: 24674694.
    Citations: 4     Fields:    Translation:Humans
  23. Warner JL, Yang P, Alterovitz G. Reversal of medical practices. Mayo Clin Proc. 2013 Oct; 88(10):1182-3. PMID: 24079691.
    Citations: 2     Fields:    Translation:Humans
  24. Warner JL, Zollanvari A, Ding Q, Zhang P, Snyder GM, Alterovitz G. Temporal phenome analysis of a large electronic health record cohort enables identification of hospital-acquired complications. J Am Med Inform Assoc. 2013 Dec; 20(e2):e281-7. PMID: 23907284.
    Citations: 7     Fields:    Translation:Humans
  25. Sonis S, Antin J, Tedaldi M, Alterovitz G. SNP-based Bayesian networks can predict oral mucositis risk in autologous stem cell transplant recipients. Oral Dis. 2013 Oct; 19(7):721-7. PMID: 23809011.
    Citations: 7     Fields:    Translation:Humans
  26. Warner JL, Alterovitz G, Bodio K, Joyce RM. External phenome analysis enables a rational federated query strategy to detect changing rates of treatment-related complications associated with multiple myeloma. J Am Med Inform Assoc. 2013 Jul-Aug; 20(4):696-9. PMID: 23515788.
    Citations: 2     Fields:    Translation:Humans
  27. Kallenbach J, Hsu WL, Dunker AK, Alterovitz G. Order-disorder interface characterization reveals critical factors for disease and drug targets. AMIA Jt Summits Transl Sci Proc. 2013; 2013:101. PMID: 24303310.
    Citations:    
  28. K Koppula S, Zollanvari A, An N, Alterovitz G. Robust prediction-based analysis for genome-wide association and expression studies. AMIA Jt Summits Transl Sci Proc. 2013; 2013:104. PMID: 24303313.
    Citations:    
  29. Warner J, Yang P, Alterovitz G. Automated synthesis and visualization of a chemotherapy treatment regimen network. Stud Health Technol Inform. 2013; 192:62-6. PMID: 23920516.
    Citations: 1     Fields:    Translation:Humans
  30. Warner J, Denny J, Kreda D, Alterovitz G. Analytic approaches to phenotypic complexity. Stud Health Technol Inform. 2013; 192:1267. PMID: 23921063.
    Citations:    
  31. Warner JL, Alterovitz G. Phenome based analysis as a means for discovering context dependent clinical reference ranges. AMIA Annu Symp Proc. 2012; 2012:1441-9. PMID: 23304424.
    Citations: 8     Fields:    Translation:HumansCells
  32. Yu YH, Chiou GY, Huang PI, Lo WL, Wang CY, Lu KH, Yu CC, Alterovitz G, Huang WC, Lo JF, Hsu HS, Chiou SH. Network biology of tumor stem-like cells identified a regulatory role of CBX5 in lung cancer. Sci Rep. 2012; 2:584. PMID: 22900142.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  33. Quo CF, Kaddi C, Phan JH, Zollanvari A, Xu M, Wang MD, Alterovitz G. Reverse engineering biomolecular systems using -omic data: challenges, progress and opportunities. Brief Bioinform. 2012 Jul; 13(4):430-45. PMID: 22833495.
    Citations: 3     Fields:    
  34. Deng M, Zollanvari A, Alterovitz G. A bayesian translational framework for knowledge propagation, discovery, and integration under specific contexts. AMIA Jt Summits Transl Sci Proc. 2012; 2012:25-34. PMID: 22779044.
    Citations:    
  35. Parikh N, Zollanvari A, Alterovitz G. An automated bayesian framework for integrative gene expression analysis and predictive medicine. AMIA Jt Summits Transl Sci Proc. 2012; 2012:95-104. PMID: 22779059.
    Citations:    
  36. Marwah K, Katzin D, Zollanvari A, Noy NF, Ramoni M, Alterovitz G. Context-specific ontology integration: a bayesian approach. AMIA Jt Summits Transl Sci Proc. 2012; 2012:79-86. PMID: 22779057.
    Citations: 2     
  37. Ting C, Alterovitz G, Merlob A, Abdi R. Genomic studies of GVHD-lessons learned thus far. Bone Marrow Transplant. 2013 Jan; 48(1):4-9. PMID: 22343675.
    Citations: 6     Fields:    Translation:HumansAnimals
  38. Alterovitz G, Tuthill C, Rios I, Modelska K, Sonis S. Personalized medicine for mucositis: Bayesian networks identify unique gene clusters which predict the response to gamma-D-glutamyl-L-tryptophan (SCV-07) for the attenuation of chemoradiation-induced oral mucositis. Oral Oncol. 2011 Oct; 47(10):951-5. PMID: 21824803.
    Citations: 5     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  39. Alterovitz G, Cavalcanti S, Muso TM, Ramoni MF, Wang M. REVERSE ENGINEERING AND SYNTHESIS OF BIOMOLECULAR SYSTEMS - Session Introduction. Pac Symp Biocomput. 2011; 300-1. PMID: 21121057.
    Citations:    
  40. Zollanvari A, Saccone NL, Bierut LJ, Ramoni MF, Alterovitz G. Is the reduction of dimensionality to a small number of features always necessary in constructing predictive models for analysis of complex diseases or behaviours? Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:3573-6. PMID: 22255111.
    Citations: 1     Fields:    Translation:Humans
  41. Chang HH, McGeachie M, Alterovitz G, Ramoni MF. Mapping transcription mechanisms from multimodal genomic data. BMC Bioinformatics. 2010 Oct 28; 11 Suppl 9:S2. PMID: 21044360.
    Citations: 5     Fields:    Translation:HumansCells
  42. Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, Kreidberg JA. Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development. Development. 2010 Apr; 137(7):1189-203. PMID: 20215353.
    Citations: 37     Fields:    Translation:AnimalsCells
  43. Alterovitz G, Xiang M, Hill DP, Lomax J, Liu J, Cherkassky M, Dreyfuss J, Mungall C, Harris MA, Dolan ME, Blake JA, Ramoni MF. Ontology engineering. Nat Biotechnol. 2010 Feb; 28(2):128-30. PMID: 20139945.
    Citations: 30     Fields:    
  44. Alterovitz G, Cavalcanti S, Muso TM, Ramoni MF, Wang M. REVERSE ENGINEERING AND SYNTHESIS OF BIOMOLECULAR SYSTEMS - Session Introduction. Pac Symp Biocomput. 2010; 383-4. PMID: 19908390.
    Citations:    
  45. Maron JL, Alterovitz G, Ramoni M, Johnson KL, Bianchi DW. High-throughput discovery and characterization of fetal protein trafficking in the blood of pregnant women. Proteomics Clin Appl. 2009 Dec; 3(12):1389-96. PMID: 20186258.
    Citations:    Fields:    
  46. Alterovitz G, Muso T, Ramoni MF. The challenges of informatics in synthetic biology: from biomolecular networks to artificial organisms. Brief Bioinform. 2010 Jan; 11(1):80-95. PMID: 19906839.
    Citations: 6     Fields:    Translation:Cells
  47. Celi LA, Hinske LC, Alterovitz G, Szolovits P. An artificial intelligence tool to predict fluid requirement in the intensive care unit: a proof-of-concept study. Crit Care. 2008; 12(6):R151. PMID: 19046450.
    Citations: 8     Fields:    Translation:Humans
  48. Alterovitz G, Jiwaji A, Ramoni MF. Automated programming for bioinformatics algorithm deployment. Bioinformatics. 2008 Feb 01; 24(3):450-1. PMID: 18174185.
    Citations: 1     Fields:    
  49. Alterovitz G, Xiang M, Liu J, Chang A, Ramoni MF. System-wide peripheral biomarker discovery using information theory. Pac Symp Biocomput. 2008; 231-42. PMID: 18229689.
    Citations: 4     Fields:    Translation:Humans
  50. Maron JL, Johnson KL, Slonim D, Lai CQ, Ramoni M, Alterovitz G, Jarrah Z, Yang Z, Bianchi DW. Gene expression analysis in pregnant women and their infants identifies unique fetal biomarkers that circulate in maternal blood. J Clin Invest. 2007 Oct; 117(10):3007-19. PMID: 17885688.
    Citations: 20     Fields:    Translation:Humans
  51. Alterovitz G, Liu J, Afkhami E, Ramoni MF. Bayesian methods for proteomics. Proteomics. 2007 Aug; 7(16):2843-55. PMID: 17654463.
    Citations: 3     Fields:    Translation:Cells
  52. Aivado M, Spentzos D, Germing U, Alterovitz G, Meng XY, Grall F, Giagounidis AA, Klement G, Steidl U, Otu HH, Czibere A, Prall WC, Iking-Konert C, Shayne M, Ramoni MF, Gattermann N, Haas R, Mitsiades CS, Fung ET, Libermann TA. Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease. Proc Natl Acad Sci U S A. 2007 Jan 23; 104(4):1307-12. PMID: 17220270.
    Citations: 23     Fields:    Translation:Humans
  53. Alterovitz G, Xiang M, Mohan M, Ramoni MF. GO PaD: the Gene Ontology Partition Database. Nucleic Acids Res. 2007 Jan; 35(Database issue):D322-7. PMID: 17098937.
    Citations: 27     Fields:    Translation:Humans
  54. Alterovitz G, Liu J, Chow J, Ramoni MF. Automation, parallelism, and robotics for proteomics. Proteomics. 2006 Jul; 6(14):4016-22. PMID: 16786489.
    Citations:    Fields:    Translation:Animals
  55. Alterovitz G, Ramoni MF. Discovering biological guilds through topological abstraction. AMIA Annu Symp Proc. 2006; 1-5. PMID: 17238291.
    Citations: 4     Fields:    Translation:Cells
  56. Aivado M, Spentzos D, Alterovitz G, Otu HH, Grall F, Giagounidis AA, Wells M, Cho JY, Germing U, Czibere A, Prall WC, Porter C, Ramoni MF, Libermann TA. Optimization and evaluation of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) with reversed-phase protein arrays for protein profiling. Clin Chem Lab Med. 2005; 43(2):133-40. PMID: 15843205.
    Citations: 7     Fields:    
  57. Alterovitz G, Aivado M, Spentzos D, Libermann TA, Ramoni M, Kohane IS. Analysis and robot pipelined automation for SELDI-TOF mass spectrometry. Conf Proc IEEE Eng Med Biol Soc. 2004; 4:3068-71. PMID: 17270926.
    Citations:    Fields:    
  58. Alterovitz G. Electrical engineering and nontechnical design variables of multiple inductive loop systems for auditoriums. J Deaf Stud Deaf Educ. 2004; 9(2):202-9. PMID: 15304441.
    Citations:    Fields:    Translation:Humans
  59. Alterovitz G, Staelin DH, Philip JH. Temporal patient state characterization using Iterative Order and Noise (ION) estimation: applications to anesthesia patient monitoring. J Clin Monit Comput. 2002 Aug; 17(6):351-9. PMID: 12885179.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.