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Bjorn Reino Olsen, M.D.,Ph.D.

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Institution
Department

Biography
1963
Voss Award for Anatomical Research
1974
A. and K.E. Schreiner Award for Biological Research
1978
Best Lecturer of the First Year Class, Student Assosication
1980
Best Lecturer of the First Year Calss, Student Association
1982
Excellence in Teaching
1983
Co-chairman, Gordon Conference "Structural Macromolecules Collagen"
1984
Co-chairman
1985
Honorary A.M. Degree
1989
Co-chairman
1992 - 1993
MERIT Award for scientific excellence
1995
Co-chairman, conference on "Molecular and Developmental Biology of Cartilage"
1995
Humboldt Research Award for Senior U.S. Scientists
1996
Member
1996
President
2000
Honorary Doctor of Science Degree
2000
Honorary Doctor of Science Degree
2001
Distinguished Faculty Award
2006
H.C. Jacobæus Prize and lecturer
2006
Member
2006
Senior Research Prize
2007
Co-chariman
2009
Chairman
2009
Co-chairman
2010
IADR Distinguished Scientist Award for Craniofacial Biology Research
2011
Chairman elect

Overview
My laboratory studies skeletal and vascular morphogenesis, growth and remodeling/repair. Work is currently directed at three project areas.

In the first project we study skeletal morphogenesis and growth. We are interested in genes that control differentiation of mesenchymal cells to chondrocytes and osteoblasts, the control of spatial patterns of mesenchymal condensations during skeletal development, the molecular mechanisms controlling the formation of ossification centers, the regulation of proliferation and differentiation of chondrocytes in growth plates, and molecular mechanisms responsible for accrual of bone mass and remodeling of the vertebrate skeleton in response to mechanical stress. In addition to using knock-out, knock-in, and conditional knock-out mice in studies of specific genes, we make extensive use of genetic approaches in mice and humans. This includes mapping of inherited disorders, gene identification and mutation detection.

In the second project we investigate the molecular basis for vascular morphogenesis, using a combination of human genetics and studies of cells in culture. In addition, we study mice with inactivated alleles for collagens that are expressed in vascular walls, and use conditional knock-out techniques to inactivate VEGF and its receptors in mice.

In the third project we are studying genetic causes of degenerative joint disease (osteoarthritis) in humans and mice. One approach involves identification of mutations responsible for early-onset osteoarthritis as part of inherited osteochondrodysplasias and cellular/molecular analyses of pathogenetic mechanisms.

Mentoring
The role of Vascular Endothelial Growth Factor in intramembranous ossification during embryonic mandibular development
Summer, 05/01/15 - 01/01/16
Role of PKD1 in the nasal cartilage upon mechanical stress induced at the mid-palatal suture
Summer, 05/30/07 - 08/10/07
Investigation of Wnt signaling and the apoptotic response to acute injury in dental tissue repair
International, 06/11/12 - 08/05/12
Characterizing the Role of TIE2 in Venous Malformations in Transgenic Mouse Model
Summer, 06/19/00 - 08/11/00
Identification of VEGF in mechanically force-induced midpalatal suture remodeling in mice
Part Time, 02/11/09 - 06/12/09
Optimization and Preparation for the Study of CD146 in Hemangioma Cell Lines
Summer, 06/21/04 - 08/06/04
Role of FGF2/9 in the growing cranial base synchondrosis
International, 06/12/12 - 08/03/12
Cherubism
Part Time, 04/01/99 - 06/20/99
Cherubism
Summer, 06/20/99 - 08/25/99
Non-endothelial origin of midpalatal suture osteoblasts
Summer, 06/11/12 - 08/13/12
Remodeling Characteristics of Mouse Midpalatal Suture Osteochondroprogenitor Cells in Response to Mechanical Force
Summer, 06/16/08 - 08/11/08

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AR072192 (OLSEN, BJORN REINO) Apr 1, 2018 - Mar 31, 2020
    NIH/NIAMS
    A mechanism for tyrosine phosphorylation of extracellular matrix proteins
    Role: Principal Investigator
  2. R13AR061249 (OLSEN, BJORN REINO) Apr 1, 2011 - Mar 31, 2012
    NIH/NIAMS
    2011 Bones &Teeth Gordon Research Conference
    Role: Principal Investigator
  3. S10RR031514 (OLSEN, BJORN REINO) Apr 1, 2011 - Mar 31, 2012
    NIH/NCRR
    MicroXCT-200 X-ray Scanner
    Role: Principal Investigator
  4. R13AR057242 (OLSEN, BJORN REINO) Apr 1, 2009 - Oct 31, 2009
    NIH/NIAMS
    2009 Gordon Research Conference on Cartilage Biology and Pathology
    Role: Principal Investigator
  5. R21AR053143 (OLSEN, BJORN REINO) Sep 21, 2005 - Aug 31, 2007
    NIH/NIAMS
    PRIMARY CILIA/CILIARY TRANSPORT IN BONE PATTERNING, GROWTH AND MECHANOSENSING
    Role: Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Olsen Lab - Mouse strains (17)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Naveh GRS, Foster JE, Silva Santisteban TM, Yang X, Olsen BR. Nonuniformity in ligaments is a structural strategy for optimizing functionality. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):9008-9013. PMID: 30126991.
    View in: PubMed
  2. Nagao M, Hamilton JL, Kc R, Berendsen AD, Duan X, Cheong CW, Li X, Im HJ, Olsen BR. Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis. Sci Rep. 2017 Oct 12; 7(1):13027. PMID: 29026147.
    View in: PubMed
  3. Zhu Q, Li M, Yan C, Lu Q, Wei S, Gao R, Yu M, Zou Y, Sriram G, Tong HJ, Hunziker W, Seneviratne CJ, Gong Z, Olsen BR, Cao T. Directed Differentiation of Human Embryonic Stem Cells to Neural Crest Stem Cells, Functional Peripheral Neurons, and Corneal Keratocytes. Biotechnol J. 2017 Dec; 12(12). PMID: 28762648.
    View in: PubMed
  4. Hu K, Olsen BR. Vascular endothelial growth factor control mechanisms in skeletal growth and repair. Dev Dyn. 2017 04; 246(4):227-234. PMID: 27750398.
    View in: PubMed
  5. Hu K, Olsen BR, Besschetnova TY. Cell autonomous ANTXR1-mediated regulation of extracellular matrix components in primary fibroblasts. Matrix Biol. 2017 10; 62:105-114. PMID: 28011198.
    View in: PubMed
  6. Hu K, Besschetnova TY, Olsen BR. Soluble VEGFR1 reverses BMP2 inhibition of intramembranous ossification during healing of cortical bone defects. J Orthop Res. 2017 07; 35(7):1461-1469. PMID: 27658810.
    View in: PubMed
  7. Olsen BR, Berendsen AD, Besschetnova TY, Duan X, Hu K. Fell-Muir Lecture: Regulatory mechanisms of skeletal and connective tissue development and homeostasis - lessons from studies of human disorders. Int J Exp Pathol. 2016 08; 97(4):296-302. PMID: 27581728.
    View in: PubMed
  8. Khullar SM, Katebi N, Herlofson BB, Tvedt D, Olsen BR. Evidence to support the hypothesis of tuberculosis as a cause of extreme osteonecrosis and osteomyelitis of the mandible in a West African population. Int J Oral Maxillofac Surg. 2016 Dec; 45(12):1600-1606. PMID: 27388429.
    View in: PubMed
  9. Hu K, Olsen BR. The roles of vascular endothelial growth factor in bone repair and regeneration. Bone. 2016 10; 91:30-8. PMID: 27353702; PMCID: PMC4996701 [Available on 10/01/17].
  10. Hamilton JL, Nagao M, Levine BR, Chen D, Olsen BR, Im HJ. Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain. J Bone Miner Res. 2016 05; 31(5):911-24. PMID: 27163679.
    View in: PubMed
  11. Huang W, Li Q, Amiry-Moghaddam M, Hokama M, Sardi SH, Nagao M, Warman ML, Olsen BR. Critical Endothelial Regulation by LRP5 during Retinal Vascular Development. PLoS One. 2016; 11(3):e0152833. PMID: 27031698; PMCID: PMC4816525.
  12. Duan X, Bradbury SR, Olsen BR, Berendsen AD. VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul; 52-54:127-140. PMID: 26899202; PMCID: PMC4875795 [Available on 05/01/17].
  13. Olsen BR, Mielenz D. Thanks to all those who reviewed for Journal of Negative Results in BioMedicine in 2015. J Negat Results Biomed. 2016; 15(1):4. PMID: 26887437; PMCID: PMC4758133.
  14. Hu K, Olsen BR. Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair. J Clin Invest. 2016 Feb; 126(2):509-26. PMID: 26731472; PMCID: PMC4731163.
  15. Toh WS, Foldager CB, Hui JH, Olsen BR, Spector M. Exploiting Stem Cell-Extracellular Matrix Interactions for Cartilage Regeneration: A Focus on Basement Membrane Molecules. Curr Stem Cell Res Ther. 2016; 11(8):618-625. PMID: 26201861.
    View in: PubMed
  16. Agarwal S, Loder S, Brownley C, Cholok D, Mangiavini L, Li J, Breuler C, Sung HH, Li S, Ranganathan K, Peterson J, Tompkins R, Herndon D, Xiao W, Jumlongras D, Olsen BR, Davis TA, Mishina Y, Schipani E, Levi B. Inhibition of Hif1a prevents both trauma-induced and genetic heterotopic ossification. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E338-47. PMID: 26721400; PMCID: PMC4725488.
  17. Berendsen AD, Olsen BR. Bone development. Bone. 2015 Nov; 80:14-18. PMID: 26453494; PMCID: PMC4602167 [Available on 11/01/16].
  18. Nagao M, Cheong CW, Olsen BR. Col2-Cre and tamoxifen-inducible Col2-CreER target different cell populations in the knee joint. Osteoarthritis Cartilage. 2016 Jan; 24(1):188-91. PMID: 26256767.
    View in: PubMed
  19. Lloyd WR, Agarwal S, Nigwekar SU, Esmonde-White K, Loder S, Fagan S, Goverman J, Olsen BR, Jumlongras D, Morris MD, Levi B. Raman spectroscopy for label-free identification of calciphylaxis. J Biomed Opt. 2015 Aug; 20(8):80501. PMID: 26263412; PMCID: PMC4689104.
  20. Berendsen AD, Olsen BR. Regulation of adipogenesis and osteogenesis in mesenchymal stem cells by vascular endothelial growth factor A. J Intern Med. 2015 Jun; 277(6):674-80. PMID: 25779338.
    View in: PubMed
  21. Hara ES, Ono M, Pham HT, Sonoyama W, Kubota S, Takigawa M, Matsumoto T, Young MF, Olsen BR, Kuboki T. Fluocinolone Acetonide Is a Potent Synergistic Factor of TGF-ß3-Associated Chondrogenesis of Bone Marrow-Derived Mesenchymal Stem Cells for Articular Surface Regeneration. J Bone Miner Res. 2015 Sep; 30(9):1585-96. PMID: 25753754.
    View in: PubMed
  22. Duan X, Murata Y, Liu Y, Nicolae C, Olsen BR, Berendsen AD. Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development. Development. 2015 Jun 01; 142(11):1984-91. PMID: 25977369; PMCID: PMC4460736.
  23. Yalak G, Olsen BR. Proteomic database mining opens up avenues utilizing extracellular protein phosphorylation for novel therapeutic applications. J Transl Med. 2015 Apr 19; 13:125. PMID: 25927841; PMCID: PMC4427915.
  24. Besschetnova TY, Ichimura T, Katebi N, St Croix B, Bonventre JV, Olsen BR. Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol. 2015 Mar; 42:56-73. PMID: 25572963; PMCID: PMC4409530.
  25. Olsen BR. Disease models: Statins give bone growth a boost. Nature. 2014 Sep 25; 513(7519):494-5. PMID: 25231860.
    View in: PubMed
  26. Yoshitaka T, Mukai T, Kittaka M, Alford LM, Masrani S, Ishida S, Yamaguchi K, Yamada M, Mizuno N, Olsen BR, Reichenberger EJ, Ueki Y. Enhanced TLR-MYD88 signaling stimulates autoinflammation in SH3BP2 cherubism mice and defines the etiology of cherubism. Cell Rep. 2014 Sep 25; 8(6):1752-1766. PMID: 25220465; PMCID: PMC4177302.
  27. Huang W, Olsen BR. Skeletal defects in Osterix-Cre transgenic mice. Transgenic Res. 2015 Feb; 24(1):167-72. PMID: 25139670; PMCID: PMC4276445.
  28. Yalak G, Ehrlich YH, Olsen BR. Ecto-protein kinases and phosphatases: an emerging field for translational medicine. J Transl Med. 2014 Jun 12; 12:165. PMID: 24923278; PMCID: PMC4071215.
  29. Dubail J, Aramaki-Hattori N, Bader HL, Nelson CM, Katebi N, Matuska B, Olsen BR, Apte SS. A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression. Genesis. 2014 Jul; 52(7):702-12. PMID: 24753090; PMCID: PMC4107014.
  30. Olsen BR. Remembering Yoshifumi Ninomiya. J Negat Results Biomed. 2014 Apr 23; 13:7. PMID: 24758326; PMCID: PMC3997191.
  31. Liu Y, Olsen BR. Distinct VEGF functions during bone development and homeostasis. Arch Immunol Ther Exp (Warsz). 2014 Oct; 62(5):363-8. PMID: 24699630.
    View in: PubMed
  32. Dellinger MT, Garg N, Olsen BR. Viewpoints on vessels and vanishing bones in Gorham-Stout disease. Bone. 2014 Jun; 63:47-52. PMID: 24583233.
    View in: PubMed
  33. Shalish M, Will LA, Fukai N, Hou B, Olsen BR. Role of polycystin-1 in bone remodeling: orthodontic tooth movement study in mutant mice. Angle Orthod. 2014 Sep; 84(5):885-90. PMID: 24559508.
    View in: PubMed
  34. Shanahan DR, Olsen BR. Opening peer-review: the democracy of science. J Negat Results Biomed. 2014 Jan 24; 13:2. PMID: 24460678; PMCID: PMC3900934.
  35. Berendsen AD, Olsen BR. How vascular endothelial growth factor-A (VEGF) regulates differentiation of mesenchymal stem cells. J Histochem Cytochem. 2014 Feb; 62(2):103-8. PMID: 24309509; PMCID: PMC3902099.
  36. Berendsen AD, Olsen BR. Osteoblast-adipocyte lineage plasticity in tissue development, maintenance and pathology. Cell Mol Life Sci. 2014 Feb; 71(3):493-7. PMID: 23934155; PMCID: PMC3947173.
  37. Volloch V, Olsen BR. Why cellular stress suppresses adipogenesis in skeletal tissue, but is ineffective in adipose tissue: control of mesenchymal cell differentiation via integrin binding sites in extracellular matrices. Matrix Biol. 2013 Oct-Nov; 32(7-8):365-71. PMID: 23792045; PMCID: PMC3858580.
  38. Duncan MB, Yang C, Tanjore H, Boyle PM, Keskin D, Sugimoto H, Zeisberg M, Olsen BR, Kalluri R. Type XVIII collagen is essential for survival during acute liver injury in mice. Dis Model Mech. 2013 Jul; 6(4):942-51. PMID: 23580202; PMCID: PMC3701214.
  39. Toh WS, Foldager CB, Olsen BR, Spector M. Basement membrane molecule expression attendant to chondrogenesis by nucleus pulposus cells and mesenchymal stem cells. J Orthop Res. 2013 Jul; 31(7):1136-43. PMID: 23508654.
    View in: PubMed
  40. Adams A, McBratney-Owen B, Newby B, Bowen ME, Olsen BR, Warman ML. Presphenoidal synchondrosis fusion in DBA/2J mice. Mamm Genome. 2013 Feb; 24(1-2):54-62. PMID: 23179633; PMCID: PMC3560942.
  41. Liu Y, Berendsen AD, Jia S, Lotinun S, Baron R, Ferrara N, Olsen BR. Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation. J Clin Invest. 2012 Sep; 122(9):3101-13. PMID: 22886301; PMCID: PMC3428080.
  42. Medici D, Olsen BR. Rapamycin inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF. PLoS One. 2012; 7(8):e42913. PMID: 22900063; PMCID: PMC3416768.
  43. Medici D, Olsen BR. The role of endothelial-mesenchymal transition in heterotopic ossification. J Bone Miner Res. 2012 Aug; 27(8):1619-22. PMID: 22806925; PMCID: PMC3432417.
  44. Katebi N, Kolpakova-Hart E, Lin CY, Olsen BR. The mouse palate and its cellular responses to midpalatal suture expansion forces. Orthod Craniofac Res. 2012 Aug; 15(3):148-58. PMID: 22812437; PMCID: PMC3812451.
  45. Jumlongras D, Lachke SA, O'Connell DJ, Aboukhalil A, Li X, Choe SE, Ho JW, Turbe-Doan A, Robertson EA, Olsen BR, Bulyk ML, Amendt BA, Maas RL. An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud. PLoS One. 2012; 7(6):e38568. PMID: 22701669.
    View in: PubMed
  46. Reichenberger EJ, Levine MA, Olsen BR, Papadaki ME, Lietman SA. The role of SH3BP2 in the pathophysiology of cherubism. Orphanet J Rare Dis. 2012 May 24; 7 Suppl 1:S5. PMID: 22640988; PMCID: PMC3359958.
  47. Papadaki ME, Lietman SA, Levine MA, Olsen BR, Kaban LB, Reichenberger EJ. Cherubism: best clinical practice. Orphanet J Rare Dis. 2012 May 24; 7 Suppl 1:S6. PMID: 22640403; PMCID: PMC3359956.
  48. Ionescu A, Kozhemyakina E, Nicolae C, Kaestner KH, Olsen BR, Lassar AB. FoxA family members are crucial regulators of the hypertrophic chondrocyte differentiation program. Dev Cell. 2012 May 15; 22(5):927-39. PMID: 22595668; PMCID: PMC3356573.
  49. Jeng L, Olsen BR, Spector M. Engineering endostatin-expressing cartilaginous constructs using injectable biopolymer hydrogels. Acta Biomater. 2012 Jul; 8(6):2203-12. PMID: 22370447.
    View in: PubMed
  50. Berendsen AD, Olsen BR. Tankyrase loses its grip on SH3BP2 in cherubism. Cell. 2011 Dec 09; 147(6):1222-3. PMID: 22153068.
    View in: PubMed
  51. Pfeffer CP, Olsen BR, Ganikhanov F, Légaré F. Imaging skeletal muscle using second harmonic generation and coherent anti-Stokes Raman scattering microscopy. Biomed Opt Express. 2011 Apr 27; 2(5):1366-76. PMID: 21559148; PMCID: PMC3087593.
  52. Medici D, Olsen BR. Transforming blood vessels into bone. Cell Cycle. 2011 Feb 01; 10(3):362-3. PMID: 21239889.
    View in: PubMed
  53. Retraction. Recent progress in studies of infantile hemangioma. J Dermatol. 2011 Jan; 38(1):107. PMID: 21218607.
    View in: PubMed
  54. Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR. Conversion of vascular endothelial cells into multipotent stem-like cells. Nat Med. 2010 Dec; 16(12):1400-6. PMID: 21102460; PMCID: PMC3209716.
  55. Clarkin C, Olsen BR. On bone-forming cells and blood vessels in bone development. Cell Metab. 2010 Oct 06; 12(4):314-316. PMID: 20889123.
    View in: PubMed
  56. Jeng L, Olsen BR, Spector M. Engineering endostatin-producing cartilaginous constructs for cartilage repair using nonviral transfection of chondrocyte-seeded and mesenchymal-stem-cell-seeded collagen scaffolds. Tissue Eng Part A. 2010 Oct; 16(10):3011-21. PMID: 20545556; PMCID: PMC3189205.
  57. Mauney J, Olsen BR, Volloch V. Matrix remodeling as stem cell recruitment event: a novel in vitro model for homing of human bone marrow stromal cells to the site of injury shows crucial role of extracellular collagen matrix. Matrix Biol. 2010 Oct; 29(8):657-63. PMID: 20828613.
    View in: PubMed
  58. Jinnin M, Ishihara T, Boye E, Olsen BR. Recent progress in studies of infantile hemangioma. J Dermatol. 2010 11; 37(11):939-55. PMID: 21039783.
    View in: PubMed
  59. Mukherjee PM, Wang CJ, Chen IP, Jafarov T, Olsen BR, Ueki Y, Reichenberger EJ. Cherubism gene Sh3bp2 is important for optimal bone formation, osteoblast differentiation, and function. Am J Orthod Dentofacial Orthop. 2010 Aug; 138(2):140.e1-140.e11; discussion 140-1. PMID: 20691350; PMCID: PMC3268358.
  60. Harnagea C, Vallières M, Pfeffer CP, Wu D, Olsen BR, Pignolet A, Légaré F, Gruverman A. Two-dimensional nanoscale structural and functional imaging in individual collagen type I fibrils. Biophys J. 2010 Jun 16; 98(12):3070-7. PMID: 20550920; PMCID: PMC2884257.
  61. Faye C, Inforzato A, Bignon M, Hartmann DJ, Muller L, Ballut L, Olsen BR, Day AJ, Ricard-Blum S. Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells. Biochem J. 2010 Apr 14; 427(3):467-75. PMID: 20156196.
    View in: PubMed
  62. Jinnin M, Ishihara T, Boye E, Olsen BR. Recent progress in studies of infantile hemangioma. J Dermatol. 2010 Apr; 37(4):283-98. PMID: 20507397.
    View in: PubMed
  63. Besschetnova TY, Kolpakova-Hart E, Guan Y, Zhou J, Olsen BR, Shah JV. Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation. Curr Biol. 2010 Jan 26; 20(2):182-7. PMID: 20096584; PMCID: PMC2990526.
  64. Nicolae C, Olsen BR. Unexpected matrix diseases and novel therapeutic strategies. Cell Tissue Res. 2010 Jan; 339(1):155-65. PMID: 19813027.
    View in: PubMed
  65. Olsen BR. When primary cilia fail. Matrix Biol. 2009 Oct; 28(8):443-4. PMID: 19939339.
    View in: PubMed
  66. Gebauer JM, Keene DR, Olsen BR, Sorokin LM, Paulsson M, Wagener R. Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment. Matrix Biol. 2009 Oct; 28(8):456-62. PMID: 19651211.
    View in: PubMed
  67. Faye C, Chautard E, Olsen BR, Ricard-Blum S. The first draft of the endostatin interaction network. J Biol Chem. 2009 Aug 14; 284(33):22041-7. PMID: 19542224; PMCID: PMC2755928.
  68. Faye C, Moreau C, Chautard E, Jetne R, Fukai N, Ruggiero F, Humphries MJ, Olsen BR, Ricard-Blum S. Molecular interplay between endostatin, integrins, and heparan sulfate. J Biol Chem. 2009 Aug 14; 284(33):22029-40. PMID: 19502598; PMCID: PMC2755927.
  69. Boye E, Olsen BR. Signaling mechanisms in infantile hemangioma. Curr Opin Hematol. 2009 May; 16(3):202-8. PMID: 19367160; PMCID: PMC2895461.
  70. Hopfer U, Hopfer H, Meyer-Schwesinger C, Loeffler I, Fukai N, Olsen BR, Stahl RA, Wolf G. Lack of type VIII collagen in mice ameliorates diabetic nephropathy. Diabetes. 2009 Jul; 58(7):1672-81. PMID: 19401424; PMCID: PMC2699847.
  71. Artois M, Bicout D, Doctrinal D, Fouchier R, Gavier-Widen D, Globig A, Hagemeijer W, Mundkur T, Munster V, Olsen B. Outbreaks of highly pathogenic avian influenza in Europe: the risks associated with wild birds. Rev Sci Tech. 2009 Apr; 28(1):69-92. PMID: 19618620.
    View in: PubMed
  72. Galli C, Fu Q, Wang W, Olsen BR, Manolagas SC, Jilka RL, O'Brien CA. Commitment to the osteoblast lineage is not required for RANKL gene expression. J Biol Chem. 2009 May 08; 284(19):12654-62. PMID: 19279010; PMCID: PMC2675994.
  73. Hou B, Kolpakova-Hart E, Fukai N, Wu K, Olsen BR. The polycystic kidney disease 1 (Pkd1) gene is required for the responses of osteochondroprogenitor cells to midpalatal suture expansion in mice. Bone. 2009 Jun; 44(6):1121-33. PMID: 19264154; PMCID: PMC2680722.
  74. Boye E, Jinnin M, Olsen BR. Infantile hemangioma: challenges, new insights, and therapeutic promise. J Craniofac Surg. 2009 Mar; 20 Suppl 1:678-84. PMID: 19190505.
    View in: PubMed
  75. Xu L, Polur I, Lim C, Servais JM, Dobeck J, Li Y, Olsen BR. Early-onset osteoarthritis of mouse temporomandibular joint induced by partial discectomy. Osteoarthritis Cartilage. 2009 Jul; 17(7):917-22. PMID: 19230720; PMCID: PMC2941347.
  76. Sun XD, Jeng L, Bolliet C, Olsen BR, Spector M. Non-viral endostatin plasmid transfection of mesenchymal stem cells via collagen scaffolds. Biomaterials. 2009 Feb; 30(6):1222-31. PMID: 19059640.
    View in: PubMed
  77. Jinnin M, Medici D, Park L, Limaye N, Liu Y, Boscolo E, Bischoff J, Vikkula M, Boye E, Olsen BR. Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma. Nat Med. 2008 Nov; 14(11):1236-46. PMID: 18931684; PMCID: PMC2593632.
  78. Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest. 2008 Nov; 118(11):3775-89. PMID: 18846253.
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  79. Medici D, Hay ED, Olsen BR. Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell. 2008 Nov; 19(11):4875-87. PMID: 18799618.
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  80. Medici D, Razzaque MS, Deluca S, Rector TL, Hou B, Kang K, Goetz R, Mohammadi M, Kuro-O M, Olsen BR, Lanske B. FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis. J Cell Biol. 2008 Aug 11; 182(3):459-65. PMID: 18678710; PMCID: PMC2500132.
  81. McBratney-Owen B, Iseki S, Bamforth SD, Olsen BR, Morriss-Kay GM. Development and tissue origins of the mammalian cranial base. Dev Biol. 2008 Oct 01; 322(1):121-32. PMID: 18680740; PMCID: PMC2847450.
  82. Pfeffer CP, Olsen BR, Ganikhanov F, Légaré F. Multimodal nonlinear optical imaging of collagen arrays. J Struct Biol. 2008 Oct; 164(1):140-5. PMID: 18664383; PMCID: PMC2580830.
  83. Kolpakova-Hart E, McBratney-Owen B, Hou B, Fukai N, Nicolae C, Zhou J, Olsen BR. Growth of cranial synchondroses and sutures requires polycystin-1. Dev Biol. 2008 Sep 15; 321(2):407-19. PMID: 18652813; PMCID: PMC2576296.
  84. Kolpakova-Hart E, Nicolae C, Zhou J, Olsen BR. Col2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes. Matrix Biol. 2008 Jul; 27(6):505-12. PMID: 18579360; PMCID: PMC2564992.
  85. Olsen BR. Treatment of mitochondrial dysfunction in patients with collagen VI mutations. Matrix Biol. 2008 May; 27(4):273. PMID: 18456160.
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  86. Saharinen P, Eklund L, Miettinen J, Wirkkala R, Anisimov A, Winderlich M, Nottebaum A, Vestweber D, Deutsch U, Koh GY, Olsen BR, Alitalo K. Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat Cell Biol. 2008 May; 10(5):527-37. PMID: 18425119.
    View in: PubMed
  87. Glotzer DJ, Zelzer E, Olsen BR. Impaired skin and hair follicle development in Runx2 deficient mice. Dev Biol. 2008 Mar 15; 315(2):459-73. PMID: 18262513; PMCID: PMC2280036.
  88. Greene AK, Kim S, Rogers GF, Fishman SJ, Olsen BR, Mulliken JB. Risk of vascular anomalies with Down syndrome. Pediatrics. 2008 Jan; 121(1):e135-40. PMID: 18166531.
    View in: PubMed
  89. Xu L, Peng H, Glasson S, Lee PL, Hu K, Ijiri K, Olsen BR, Goldring MB, Li Y. Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis. Arthritis Rheum. 2007 Aug; 56(8):2663-73. PMID: 17665456.
    View in: PubMed
  90. Kolpakova-Hart E, Jinnin M, Hou B, Fukai N, Olsen BR. Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms. Dev Biol. 2007 Sep 15; 309(2):273-84. PMID: 17698054; PMCID: PMC2062520.
  91. Li Y, Xu L, Olsen BR. Lessons from genetic forms of osteoarthritis for the pathogenesis of the disease. Osteoarthritis Cartilage. 2007 Oct; 15(10):1101-5. PMID: 17572112; PMCID: PMC2062521.
  92. Pfeffer CP, Olsen BR, Légaré F. Second harmonic generation imaging of fascia within thick tissue block. Opt Express. 2007 Jun 11; 15(12):7296-302. PMID: 19547053.
    View in: PubMed
  93. Marneros AG, She H, Zambarakji H, Hashizume H, Connolly EJ, Kim I, Gragoudas ES, Miller JW, Olsen BR. Endogenous endostatin inhibits choroidal neovascularization. FASEB J. 2007 Dec; 21(14):3809-18. PMID: 17526870.
    View in: PubMed
  94. Légaré F, Pfeffer C, Olsen BR. The role of backscattering in SHG tissue imaging. Biophys J. 2007 Aug 15; 93(4):1312-20. PMID: 17449666; PMCID: PMC1929026.
  95. Reginato AM, Olsen BR. Genetics and experimental models of crystal-induced arthritis. Lessons learned from mice and men: is it crystal clear? Curr Opin Rheumatol. 2007 Mar; 19(2):134-45. PMID: 17278928.
    View in: PubMed
  96. Olsen BR. Anthrax toxin receptors and infantile systemic hyalinosis. Matrix Biol. 2007 Mar; 26(2):73-4. PMID: 17280935.
    View in: PubMed
  97. Hou B, Fukai N, Olsen BR. Mechanical force-induced midpalatal suture remodeling in mice. Bone. 2007 Jun; 40(6):1483-93. PMID: 17398175; PMCID: PMC1939974.
  98. Ueki Y, Lin CY, Senoo M, Ebihara T, Agata N, Onji M, Saheki Y, Kawai T, Mukherjee PM, Reichenberger E, Olsen BR. Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. Cell. 2007 Jan 12; 128(1):71-83. PMID: 17218256.
    View in: PubMed
  99. Laake, P, Benestad, HB, Olsen, BR . Research methodology in medicine and biological sciences. 2007.
  100. Lam NP, Li Y, Waldman AB, Brussiau J, Lee PL, Olsen BR, Xu L. Age-dependent increase of discoidin domain receptor 2 and matrix metalloproteinase 13 expression in temporomandibular joint cartilage of type IX and type XI collagen-deficient mice. Arch Oral Biol. 2007 Jun; 52(6):579-84. PMID: 17125729; PMCID: PMC3825249.
  101. Hu K, Xu L, Cao L, Flahiff CM, Brussiau J, Ho K, Setton LA, Youn I, Guilak F, Olsen BR, Li Y. Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen. Arthritis Rheum. 2006 Sep; 54(9):2891-900. PMID: 16947423.
    View in: PubMed
  102. Adiguzel E, Hou G, Mulholland D, Hopfer U, Fukai N, Olsen B, Bendeck M. Migration and growth are attenuated in vascular smooth muscle cells with type VIII collagen-null alleles. Arterioscler Thromb Vasc Biol. 2006 Jan; 26(1):56-61. PMID: 16269661.
    View in: PubMed
  103. Marneros AG, Fan J, Yokoyama Y, Gerber HP, Ferrara N, Crouch RK, Olsen BR. Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function. Am J Pathol. 2005 Nov; 167(5):1451-9. PMID: 16251428; PMCID: PMC1603772.
  104. Eklund L, Olsen BR. Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp Cell Res. 2006 Mar 10; 312(5):630-41. PMID: 16225862.
    View in: PubMed
  105. Olsen B. Nearly all cells in vertebrates and many cells in invertebrates contain primary cilia. Matrix Biol. 2005 Oct; 24(7):449-50. PMID: 16226676.
    View in: PubMed
  106. Hopfer U, Fukai N, Hopfer H, Wolf G, Joyce N, Li E, Olsen BR. Targeted disruption of Col8a1 and Col8a2 genes in mice leads to anterior segment abnormalities in the eye. FASEB J. 2005 Aug; 19(10):1232-44. PMID: 16051690.
    View in: PubMed
  107. Kolpakova E, Olsen BR. Wnt/beta-catenin--a canonical tale of cell-fate choice in the vertebrate skeleton. Dev Cell. 2005 May; 8(5):626-7. PMID: 15866155.
    View in: PubMed
  108. Marneros AG, Olsen BR. Physiological role of collagen XVIII and endostatin. FASEB J. 2005 May; 19(7):716-28. PMID: 15857886.
    View in: PubMed
  109. Zelzer E, Olsen BR. Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair. Curr Top Dev Biol. 2005; 65:169-87. PMID: 15642383.
    View in: PubMed
  110. Gaetzner S, Deckers MM, Stahl S, Löwik C, Olsen BR, Felbor U. Endostatin's heparan sulfate-binding site is essential for inhibition of angiogenesis and enhances in situ binding to capillary-like structures in bone explants. Matrix Biol. 2005 Jan; 23(8):557-61. PMID: 15694132.
    View in: PubMed
  111. Olsen B. From the Editors' desk. Matrix Biol. 2004 Nov; 23(7):417-9. PMID: 15579308.
    View in: PubMed
  112. Xu L, Peng H, Wu D, Hu K, Goldring MB, Olsen BR, Li Y. Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. J Biol Chem. 2005 Jan 07; 280(1):548-55. PMID: 15509586.
    View in: PubMed
  113. Moulton KS, Olsen BR, Sonn S, Fukai N, Zurakowski D, Zeng X. Loss of collagen XVIII enhances neovascularization and vascular permeability in atherosclerosis. Circulation. 2004 Sep 07; 110(10):1330-6. PMID: 15313955.
    View in: PubMed
  114. Olsen B. From the Editor's desk. Matrix Biol. 2004 Aug; 23(5):265-6. PMID: 15464358.
    View in: PubMed
  115. Li Q, Olsen BR. Increased angiogenic response in aortic explants of collagen XVIII/endostatin-null mice. Am J Pathol. 2004 Aug; 165(2):415-24. PMID: 15277216; PMCID: PMC1618585.
  116. Heng BC, Cao T, Stanton LW, Robson P, Olsen B. Strategies for directing the differentiation of stem cells into the osteogenic lineage in vitro. J Bone Miner Res. 2004 09; 19(9):1379-94. PMID: 15312238.
    View in: PubMed
  117. Nawshad A, LaGamba D, Olsen BR, Hay ED. Laser capture microdissection (LCM) for analysis of gene expression in specific tissues during embryonic epithelial-mesenchymal transformation. Dev Dyn. 2004 Jul; 230(3):529-34. PMID: 15188437.
    View in: PubMed
  118. Wang W, Wang YG, Reginato AM, Glotzer DJ, Fukai N, Plotkina S, Karsenty G, Olsen BR. Groucho homologue Grg5 interacts with the transcription factor Runx2-Cbfa1 and modulates its activity during postnatal growth in mice. Dev Biol. 2004 Jun 15; 270(2):364-81. PMID: 15183720.
    View in: PubMed
  119. Pfander D, Kobayashi T, Knight MC, Zelzer E, Chan DA, Olsen BR, Giaccia AJ, Johnson RS, Haase VH, Schipani E. Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development. 2004 May; 131(10):2497-508. PMID: 15128677.
    View in: PubMed
  120. Bhutto IA, Kim SY, McLeod DS, Merges C, Fukai N, Olsen BR, Lutty GA. Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2004 May; 45(5):1544-52. PMID: 15111613.
    View in: PubMed
  121. Marneros AG, Norris JE, Watanabe S, Reichenberger E, Olsen BR. Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11. J Invest Dermatol. 2004 May; 122(5):1126-32. PMID: 15140214.
    View in: PubMed
  122. Zelzer E, Mamluk R, Ferrara N, Johnson RS, Schipani E, Olsen BR. VEGFA is necessary for chondrocyte survival during bone development. Development. 2004 May; 131(9):2161-71. PMID: 15073147.
    View in: PubMed
  123. Hamano Y, Sugimoto H, Soubasakos MA, Kieran M, Olsen BR, Lawler J, Sudhakar A, Kalluri R. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res. 2004 Mar 01; 64(5):1570-4. PMID: 14996710.
    View in: PubMed
  124. Menzel O, Bekkeheien RC, Reymond A, Fukai N, Boye E, Kosztolanyi G, Aftimos S, Deutsch S, Scott HS, Olsen BR, Antonarakis SE, Guipponi M. Knobloch syndrome: novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin. Hum Mutat. 2004 Jan; 23(1):77-84. PMID: 14695535.
    View in: PubMed
  125. Jumlongras D, Lin JY, Chapra A, Seidman CE, Seidman JG, Maas RL, Olsen BR. A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia. Hum Genet. 2004 Feb; 114(3):242-9. PMID: 14689302.
    View in: PubMed
  126. Marneros AG, Keene DR, Hansen U, Fukai N, Moulton K, Goletz PL, Moiseyev G, Pawlyk BS, Halfter W, Dong S, Shibata M, Li T, Crouch RK, Bruckner P, Olsen BR. Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function. EMBO J. 2004 Jan 14; 23(1):89-99. PMID: 14685281; PMCID: PMC1271654.
  127. Ricard-Blum S, Féraud O, Lortat-Jacob H, Rencurosi A, Fukai N, Dkhissi F, Vittet D, Imberty A, Olsen BR, van der Rest M. Characterization of endostatin binding to heparin and heparan sulfate by surface plasmon resonance and molecular modeling: role of divalent cations. J Biol Chem. 2004 Jan 23; 279(4):2927-36. PMID: 14585835.
    View in: PubMed
  128. Ylikärppä R, Eklund L, Sormunen R, Kontiola AI, Utriainen A, Määttä M, Fukai N, Olsen BR, Pihlajaniemi T. Lack of type XVIII collagen results in anterior ocular defects. FASEB J. 2003 Dec; 17(15):2257-9. PMID: 14525950.
    View in: PubMed
  129. Li Q, Yu Y, Bischoff J, Mulliken JB, Olsen BR. Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin. J Pathol. 2003 Oct; 201(2):296-302. PMID: 14517847.
    View in: PubMed
  130. Rice R, Rice DP, Olsen BR, Thesleff I. Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol. 2003 Oct 01; 262(1):75-87. PMID: 14512019.
    View in: PubMed
  131. Xu L, Flahiff CM, Waldman BA, Wu D, Olsen BR, Setton LA, Li Y. Osteoarthritis-like changes and decreased mechanical function of articular cartilage in the joints of mice with the chondrodysplasia gene (cho). Arthritis Rheum. 2003 Sep; 48(9):2509-18. PMID: 13130470.
    View in: PubMed
  132. Ylikärppä R, Eklund L, Sormunen R, Muona A, Fukai N, Olsen BR, Pihlajaniemi T. Double knockout mice reveal a lack of major functional compensation between collagens XV and XVIII. Matrix Biol. 2003 Sep; 22(5):443-8. PMID: 14614990.
    View in: PubMed
  133. Marneros AG, Olsen BR. Age-dependent iris abnormalities in collagen XVIII/endostatin deficient mice with similarities to human pigment dispersion syndrome. Invest Ophthalmol Vis Sci. 2003 Jun; 44(6):2367-72. PMID: 12766032.
    View in: PubMed
  134. Zelzer E, Olsen BR. The genetic basis for skeletal diseases. Nature. 2003 May 15; 423(6937):343-8. PMID: 12748653.
    View in: PubMed
  135. Czipri M, Otto JM, Cs-Szabó G, Kamath RV, Vermes C, Firneisz G, Kolman KJ, Watanabe H, Li Y, Roughley PJ, Yamada Y, Olsen BR, Glant TT. Genetic rescue of chondrodysplasia and the perinatal lethal effect of cartilage link protein deficiency. J Biol Chem. 2003 Oct 03; 278(40):39214-23. PMID: 12732630.
    View in: PubMed
  136. Rossi M, Morita H, Sormunen R, Airenne S, Kreivi M, Wang L, Fukai N, Olsen BR, Tryggvason K, Soininen R. Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney. EMBO J. 2003 Jan 15; 22(2):236-45. PMID: 12514129; PMCID: PMC140094.
  137. McLean, W, Olsen, BR. . Diseases of excess bone formation. Bone Formation. Vol 1 of Topics in Bone Biology. Eds. Bronner, F, Farach-Carson, M.C. 2003; 120-137.
  138. Olsen, BR. . Bone morphogenesis and embryologic development. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 5th edition. 2003; 9-13.
  139. Szymko-Bennett YM, Kurima K, Olsen B, Seegmiller R, Griffith AJ. Auditory function associated with Col11a1 haploinsufficiency in chondrodysplasia (cho) mice. Hear Res. 2003 Jan; 175(1-2):178-82. PMID: 12527136.
    View in: PubMed
  140. Pfeffer C, Olsen BR. Editorial: Journal of negative results in biomedicine. J Negat Results Biomed. 2002 Nov 12; 1:2. PMID: 12459050; PMCID: PMC149424.
  141. Suzuki OT, Sertié AL, Der Kaloustian VM, Kok F, Carpenter M, Murray J, Czeizel AE, Kliemann SE, Rosemberg S, Monteiro M, Olsen BR, Passos-Bueno MR. Molecular analysis of collagen XVIII reveals novel mutations, presence of a third isoform, and possible genetic heterogeneity in Knobloch syndrome. Am J Hum Genet. 2002 Dec; 71(6):1320-9. PMID: 12415512; PMCID: PMC378571.
  142. Reginato AM, Olsen BR. The role of structural genes in the pathogenesis of osteoarthritic disorders. Arthritis Res. 2002; 4(6):337-45. PMID: 12453309; PMCID: PMC153840.
  143. Felbor U, Kessler B, Mothes W, Goebel HH, Ploegh HL, Bronson RT, Olsen BR. Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):7883-8. PMID: 12048238; PMCID: PMC122989.
  144. Samuel RE, Lee CR, Ghivizzani SC, Evans CH, Yannas IV, Olsen BR, Spector M. Delivery of plasmid DNA to articular chondrocytes via novel collagen-glycosaminoglycan matrices. Hum Gene Ther. 2002 May 01; 13(7):791-802. PMID: 11975846.
    View in: PubMed
  145. Matsuno H, Yudoh K, Uzuki M, Nakazawa F, Sawai T, Yamaguchi N, Olsen BR, Kimura T. Treatment with the angiogenesis inhibitor endostatin: a novel therapy in rheumatoid arthritis. J Rheumatol. 2002 May; 29(5):890-5. PMID: 12022345.
    View in: PubMed
  146. Wang WF, Wang YG, Reginato AM, Plotkina S, Gridley T, Olsen BR. Growth defect in Grg5 null mice is associated with reduced Ihh signaling in growth plates. Dev Dyn. 2002 May; 224(1):79-89. PMID: 11984876.
    View in: PubMed
  147. Fukai N, Eklund L, Marneros AG, Oh SP, Keene DR, Tamarkin L, Niemelä M, Ilves M, Li E, Pihlajaniemi T, Olsen BR. Lack of collagen XVIII/endostatin results in eye abnormalities. EMBO J. 2002 Apr 02; 21(7):1535-44. PMID: 11927538; PMCID: PMC125362.
  148. Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR. Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr; 129(8):1893-904. PMID: 11934855.
    View in: PubMed
  149. Brouillard P, Boon LM, Mulliken JB, Enjolras O, Ghassibé M, Warman ML, Tan OT, Olsen BR, Vikkula M. Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ("glomangiomas"). Am J Hum Genet. 2002 Apr; 70(4):866-74. PMID: 11845407; PMCID: PMC379115.
  150. Sorensen DR, Read TA, Porwol T, Olsen BR, Timpl R, Sasaki T, Iversen PO, Benestad HB, Sim BK, Bjerkvig R. Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma. Neuro Oncol. 2002 01; 4(1):1-8. PMID: 11772427; PMCID: PMC1920634.
  151. Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reginato AM, Wang H, Cundy T, Glorieux FH, Lev D, Zacharin M, Oexle K, Marcelino J, Suwairi W, Heeger S, Sabatakos G, Apte S, Adkins WN, Allgrove J, Arslan-Kirchner M, Batch JA, Beighton P, Black GC, Boles RG, Boon LM, Borrone C, Brunner HG, Carle GF, Dallapiccola B, De Paepe A, Floege B, Halfhide ML, Hall B, Hennekam RC, Hirose T, Jans A, Jüppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A, LaCombe D, Lambert M, Lemyre E, Letteboer T, Peltonen L, Ramesar RS, Romanengo M, Somer H, Steichen-Gersdorf E, Steinmann B, Sullivan B, Superti-Furga A, Swoboda W, van den Boogaard MJ, Van Hul W, Vikkula M, Votruba M, Zabel B, Garcia T, Baron R, Olsen BR, Warman ML. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell. 2001 Nov 16; 107(4):513-23. PMID: 11719191.
    View in: PubMed
  152. Zorick TS, Mustacchi Z, Bando SY, Zatz M, Moreira-Filho CA, Olsen B, Passos-Bueno MR. High serum endostatin levels in Down syndrome: implications for improved treatment and prevention of solid tumours. Eur J Hum Genet. 2001 Nov; 9(11):811-4. PMID: 11781696.
    View in: PubMed
  153. Marneros AG, Norris JE, Olsen BR, Reichenberger E. Clinical genetics of familial keloids. Arch Dermatol. 2001 Nov; 137(11):1429-34. PMID: 11708945.
    View in: PubMed
  154. McLean W, Olsen BR. Mouse models of abnormal skeletal development and homeostasis. Trends Genet. 2001 Oct; 17(10):S38-43. PMID: 11585675.
    View in: PubMed
  155. Read TA, Farhadi M, Bjerkvig R, Olsen BR, Rokstad AM, Huszthy PC, Vajkoczy P. Intravital microscopy reveals novel antivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells. Cancer Res. 2001 Sep 15; 61(18):6830-7. PMID: 11559558.
    View in: PubMed
  156. Olsen B. [Humanitarian challenges of a new millennium]. Tidsskr Nor Laegeforen. 2001 Sep 10; 121(21):2527-30. PMID: 11875933.
    View in: PubMed
  157. Marneros AG, Olsen BR. The role of collagen-derived proteolytic fragments in angiogenesis. Matrix Biol. 2001 Sep; 20(5-6):337-45. PMID: 11566268.
    View in: PubMed
  158. Lavrin IO, McLean W, Seegmiller RE, Olsen BR, Hay ED. The mechanism of palatal clefting in the Col11a1 mutant mouse. Arch Oral Biol. 2001 Sep; 46(9):865-9. PMID: 11420059.
    View in: PubMed
  159. Zelzer E, Glotzer DJ, Hartmann C, Thomas D, Fukai N, Soker S, Olsen BR. Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev. 2001 Aug; 106(1-2):97-106. PMID: 11472838.
    View in: PubMed
  160. Thomas KL, Leduc I, Olsen B, Thomas CE, Cameron DW, Elkins C. Cloning, overexpression, purification, and immunobiology of an 85-kilodalton outer membrane protein from Haemophilus ducreyi. Infect Immun. 2001 Jul; 69(7):4438-46. PMID: 11401984; PMCID: PMC98517.
  161. Ueki Y, Tiziani V, Santanna C, Fukai N, Maulik C, Garfinkle J, Ninomiya C, doAmaral C, Peters H, Habal M, Rhee-Morris L, Doss JB, Kreiborg S, Olsen BR, Reichenberger E. Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubism. Nat Genet. 2001 Jun; 28(2):125-6. PMID: 11381256.
    View in: PubMed
  162. Jumlongras D, Bei M, Stimson JM, Wang WF, DePalma SR, Seidman CE, Felbor U, Maas R, Seidman JG, Olsen BR. A nonsense mutation in MSX1 causes Witkop syndrome. Am J Hum Genet. 2001 Jul; 69(1):67-74. PMID: 11369996; PMCID: PMC1226049.
  163. Reichenberger E, Tiziani V, Watanabe S, Park L, Ueki Y, Santanna C, Baur ST, Shiang R, Grange DK, Beighton P, Gardner J, Hamersma H, Sellars S, Ramesar R, Lidral AC, Sommer A, Raposo do Amaral CM, Gorlin RJ, Mulliken JB, Olsen BR. Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANK. Am J Hum Genet. 2001 Jun; 68(6):1321-6. PMID: 11326338; PMCID: PMC1226118.
  164. Xu L, Tan L, Goldring MB, Olsen BR, Li Y. Expression of frizzled genes in mouse costochondral chondrocytes. Matrix Biol. 2001 Apr; 20(2):147-51. PMID: 11334716.
    View in: PubMed
  165. Boye E, Yu Y, Paranya G, Mulliken JB, Olsen BR, Bischoff J. Clonality and altered behavior of endothelial cells from hemangiomas. J Clin Invest. 2001 Mar; 107(6):745-52. PMID: 11254674; PMCID: PMC208946.
  166. Rieger DK, Reichenberger E, McLean W, Sidow A, Olsen BR. A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice. Genomics. 2001 Feb 15; 72(1):61-72. PMID: 11247667.
    View in: PubMed
  167. Reginato, A, Wang, W, Olsen, BR. . Vol 1, pp.189-212. Developmental biology of bone. Osteoporosis. (Marcus, R., Feldman, D., Kelsey, J., eds). 2001; 1:189-212.
  168. Marneros AG, Mehenni H, Reichenberger E, Antonarakis SE, Krieg T, Olsen BR. Gene for the human transmembrane-type protein tyrosine phosphatase H (PTPRH): genomic structure, fine-mapping and its exclusion as a candidate for Peutz-Jeghers syndrome. Cytogenet Cell Genet. 2001; 92(3-4):213-6. PMID: 11435690.
    View in: PubMed
  169. Karttunen, L, Felbor, U, Vikkula, M, and Olsen, BR. , pp. 784-795. Vascular matrix and disorders. Hematopoiesis: A Developmental Approach. (Zon, LI, ed). 2001; 784-795.
  170. Aszódi A, Hunziker EB, Olsen BR, Fässler R. The role of collagen II and cartilage fibril-associated molecules in skeletal development. Osteoarthritis Cartilage. 2001; 9 Suppl A:S150-9. PMID: 11680679.
    View in: PubMed
  171. Irrthum A, Brouillard P, Enjolras O, Gibbs NF, Eichenfield LF, Olsen BR, Mulliken JB, Boon LM, Vikkula M. Linkage disequilibrium narrows locus for venous malformation with glomus cells (VMGLOM) to a single 1.48 Mbp YAC. Eur J Hum Genet. 2001 Jan; 9(1):34-8. PMID: 11175297.
    View in: PubMed
  172. Read TA, Sorensen DR, Mahesparan R, Enger PO, Timpl R, Olsen BR, Hjelstuen MH, Haraldseth O, Bjerkvig R. Local endostatin treatment of gliomas administered by microencapsulated producer cells. Nat Biotechnol. 2001 Jan; 19(1):29-34. PMID: 11135548.
    View in: PubMed
  173. Ferreras M, Felbor U, Lenhard T, Olsen BR, Delaissé J. Generation and degradation of human endostatin proteins by various proteinases. FEBS Lett. 2000 Dec 15; 486(3):247-51. PMID: 11119712.
    View in: PubMed
  174. Reichenberger E, Baur S, Sukotjo C, Olsen BR, Karimbux NY, Nishimura I. Collagen XII mutation disrupts matrix structure of periodontal ligament and skin. J Dent Res. 2000 Dec; 79(12):1962-8. PMID: 11201046.
    View in: PubMed
  175. Zätterström UK, Fukai N, Olsen BR. [A fragment of collagen XVIII inhibits angiogenesis]. Tidsskr Nor Laegeforen. 2000 Nov 30; 120(29):3547-50. PMID: 11188382.
    View in: PubMed
  176. Brouillard P, Olsen BR, Vikkula M. High-resolution physical and transcript map of the locus for venous malformations with glomus cells (VMGLOM) on chromosome 1p21-p22. Genomics. 2000 Jul 01; 67(1):96-101. PMID: 10945476.
    View in: PubMed
  177. Chen R, Gao B, Huang C, Olsen B, Rotundo RF, Blumenstock F, Saba TM. Transglutaminase-mediated fibronectin multimerization in lung endothelial matrix in response to TNF-alpha. Am J Physiol Lung Cell Mol Physiol. 2000 Jul; 279(1):L161-74. PMID: 10893215.
    View in: PubMed
  178. Spayde EC, Joshi AP, Wilcox WR, Briggs M, Cohn DH, Olsen BR. Exon skipping mutation in the COL9A2 gene in a family with multiple epiphyseal dysplasia. Matrix Biol. 2000 May; 19(2):121-8. PMID: 10842095.
    View in: PubMed
  179. Zatterstrom UK, Felbor U, Fukai N, Olsen BR. Collagen XVIII/endostatin structure and functional role in angiogenesis. Cell Struct Funct. 2000 Apr; 25(2):97-101. PMID: 10885579.
    View in: PubMed
  180. Felbor U, Dreier L, Bryant RA, Ploegh HL, Olsen BR, Mothes W. Secreted cathepsin L generates endostatin from collagen XVIII. EMBO J. 2000 Mar 15; 19(6):1187-94. PMID: 10716919; PMCID: PMC305660.
  181. Olsen BR, Reginato AM, Wang W. Bone development. Annu Rev Cell Dev Biol. 2000; 16:191-220. PMID: 11031235.
    View in: PubMed
  182. Olsen, BR. . Matrix molecules and their ligands. Principles of Tissue Engineering. R.G. (Lanza, R, Langer, R, and Vacanti, J. ed). 2nd ed. 2000.
  183. Ting K, Ramachandran H, Chung KS, Shah-Hosseini N, Olsen BR, Nishimura I. A short isoform of Col9a1 supports alveolar bone repair. Am J Pathol. 1999 Dec; 155(6):1993-9. PMID: 10595929; PMCID: PMC1866927.
  184. Otto JM, Cs-Szabó G, Gallagher J, Velins S, Mikecz K, Buzás EI, Enders JT, Li Y, Olsen BR, Glant TT. Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis. Arthritis Rheum. 1999 Dec; 42(12):2524-31. PMID: 10615997.
    View in: PubMed
  185. Olsen BR. Life without perlecan has its problems. J Cell Biol. 1999 Nov 29; 147(5):909-12. PMID: 10579711; PMCID: PMC2169336.
  186. Annunen S, Körkkö J, Czarny M, Warman ML, Brunner HG, Kääriäinen H, Mulliken JB, Tranebjaerg L, Brooks DG, Cox GF, Cruysberg JR, Curtis MA, Davenport SL, Friedrich CA, Kaitila I, Krawczynski MR, Latos-Bielenska A, Mukai S, Olsen BR, Shinno N, Somer M, Vikkula M, Zlotogora J, Prockop DJ, Ala-Kokko L. Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes. Am J Hum Genet. 1999 Oct; 65(4):974-83. PMID: 10486316; PMCID: PMC1288268.
  187. Yamaguchi N, Anand-Apte B, Lee M, Sasaki T, Fukai N, Shapiro R, Que I, Lowik C, Timpl R, Olsen BR. Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J. 1999 Aug 16; 18(16):4414-23. PMID: 10449407; PMCID: PMC1171516.
  188. Melander A, Olsson J, Lindberg G, Salzman A, Howard T, Stang P, Lydick E, Emslie-Smith A, Boyle DI, Evans JM, Macdonald TM, Bain J, Sullivan F, Juhl C, Pørksen N, Sturis J, Hollingdal M, Pincus S, Veldhuis J, Dejgaard A, Schmitz O, Kristensen JS, Frandsen KB, Bayer T, Müller P, Dunning BE, Paladini S, Gutierrez C, Deacon R, Valentin M, Grunberger G, Weston WM, Patwardhan R, Rappaport EB, Sargeant LA, Wareham NJ, Khaw KT, Zethelius B, Lithell H, Hales CN, Berne C, Lakka HM, Oksanen L, Tuomainen TP, Kontula K, Salonen JT, Dekker JM, de Boks P, de Vegt F, Stehouwer CD, Nijpels G, Bouter LM, Heine RJ, Bruno G, Cavallo-Perin P, Bargero G, D'Errico N, Borra M, Macchia G, Pagano G, Newton RW, Ruta DA, New JP, Wallace C, Roxburgh MA, Young RJ, Vaughan NJ, Elliott P, Brennan G, Devers M, MacAlpine R, Steinke D, Lawson DH, Decallonne B, Casteels K, Gysemans C, Bouillon R, Mathieu C, Linn T, Strate C, Schneider K, Funda DP, Jirsa M, Kozáková H, Kaas A, Kofronová O, Tlaskalová-Hogenová H, Buschard K, Wanka H, Hartmann A, Kuttler B, Rasmussen SB, Sørensen TS, Markholst H, Petersen JS, Karounos D, Dyrberg T, Mabley JG, Haskó G, Szabó C, Seissler J, Nguyen TB, Steinbrenner H, Scherbaum WA, Cipriani R, Gabriele A, Sensi M, Guidobaldi L, Pantellini F, Cerrito MG, Scarpa S, Di Mario U, Morano S, Ceolotto G, Iori E, Baritono E, Del Prato S, Semplicini A, Trevisan R, Zerbini G, Meregalli G, Asnaghi V, Tentori F, Maestroni A, Mangili R, Marescotti C, Vedovato M, Tiengo A, Tadjieva J, Mankovsky BN, Van Aken S, Raes A, Vande Walle J, Matthys D, Craen M, Hansen HP, Lund SS, Rossing P, Jensen T, Parving HH, Andersen S, Tarnow L, Hansen BV, Trautner C, Haastert B, Ennenbach N, Willich S, Tabák ÁG, Orchard TJ, Spranger J, Preissner KT, Schatz H, Pfeiffer A, Cantón A, Burgos R, Hernández C, Lecube A, Mesa J, Segura RM, Mateo C, Simó R, Fathallah L, Greene DA, Obrosova I, Gilbert RE, Kelly DJ, Cox AJ, Berka-Wilkinson JL, Taylor HR, Panagiotopoulos S, Lee V, Jerums G, Cooper ME, Hitman GA, Aganna E, Ogunkolade WB, Rema M, Deepa R, Shanthi-Rani CS, Barakat K, Kumarajeewa TR, Cassell PG, McDermott MF, Mohan V, Ways K, Bursell S, Devries T, Woodworth J, Alatorre C, King G, Aiello LP, Karisen AE, Pavlovic D, Nielsen K, Jensen J, Andersen HU, Pociot F, Mandrup-Poulsen T, Eizirik DL, Nerup J, Lortz S, Tiedge M, Lenzen S, Lally FJ, Bone AJ, Darville MI, Ho YS, Sternesjö J, Sandler S, Chen MC, Schuit F, Pipeleers DG, Merezak S, Hardikar A, Hoet JJ, Remacle C, Reusens B, Bréant B, Garofano A, Czernichow P, Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Nakano R, Komeda K, Eto K, Tobe K, Kimura S, Kadowaki T, Ide T, Murakami K, Tsunoda M, Mochizuki T, Ozanne SE, Nave BT, Wang CL, Dorling MW, Petry CJ, Koopmans SJ, van der Bent C, Que I, Radder JK, Sebokova E, Sana AK, Klimes I, Ruderman N, Morviducci L, Pastore L, Morelli S, Sagratella E, Zorretta D, Buongiomo A, Tamburrano G, Giaccari A, Martinenghi S, De Angelis GC, Ravasi F, Bifari F, Bordignon C, Falqui L, Kessler A, Dransfeld O, Sasson S, Tomas E, Zorzano A, Eckel J, Thorsby P, Rosenfalck AM, Kjems L, Hanssen KF, Madsbad S, Birkeland KI, Hamilton-Wessler M, Markussen J, Bergman RN, Melki V, Hanaire-Broutin H, Bessières-Lacombe S, Tauber JP, Home PD, Lindholm A, Riis A, Rosenstock J, Schwartz S, Clark C, Edwards M, Donley D, Swift P, Mortensen HB, Lynggaard H, Hougaard P, Cull CA, Neil HA, Frighi V, Manley SE, Holman RR, Turner RC, Steiner G, Davis WA, Weeraratna T, Bruce DG, Davis TM, Vergès B, Duvillard L, Pont F, Florentin E, Gambert P, Benko B, Ljubic S, Turk Z, Granic M, März W, Wollschläger H, Klein G, Neiss A, Wehling M, Huxtable SJ, Saker PJ, Walker M, Frayling TM, Levy JC, O'Rahilly S, Hattersley AT, McCarthy MI, Orecchio A, Giacchini A, Dominici R, Canettieri G, Trinti B, Zani M, Andreoli M, Sciacchitano S, de Silva AM, Whitecross K, Pasco J, Kotowicz M, Nicholson G, Zimmet P, Boyko EJ, Collier GR, Frittitta L, Pizzuti A, Argiolas A, Graci S, Goldfine ID, Bozzali M, Ercolino T, et al. 35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. Diabetologia. 1999 Aug; 42(Suppl 1):A1-A330. PMID: 27770183.
    View in: PubMed
  189. Kania AM, Reichenberger E, Baur ST, Karimbux NY, Taylor RW, Olsen BR, Nishimura I. Structural variation of type XII collagen at its carboxyl-terminal NC1 domain generated by tissue-specific alternative splicing. J Biol Chem. 1999 Jul 30; 274(31):22053-9. PMID: 10419532.
    View in: PubMed
  190. Tiziani V, Reichenberger E, Buzzo CL, Niazi S, Fukai N, Stiller M, Peters H, Salzano FM, Raposo do Amaral CM, Olsen BR. The gene for cherubism maps to chromosome 4p16. Am J Hum Genet. 1999 Jul; 65(1):158-66. PMID: 10364528; PMCID: PMC1378086.
  191. Olsen BR. Genetic regulation of skeletal patterning, differentiation, and growth. Bone. 1999 Jul; 25(1):77-9. PMID: 10423025.
    View in: PubMed
  192. Boon LM, Brouillard P, Irrthum A, Karttunen L, Warman ML, Rudolph R, Mulliken JB, Olsen BR, Vikkula M. A gene for inherited cutaneous venous anomalies ("glomangiomas") localizes to chromosome 1p21-22. Am J Hum Genet. 1999 Jul; 65(1):125-33. PMID: 10364524; PMCID: PMC1378082.
  193. Olsen, BR. . Bone morphogenesis and embryological development. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism 4th edition. 1999; 11-14.
  194. Ninomiya Y, and Olsen BR. . Collagens. Guidebook to the Extracellular Matrix, Anchor, and Adhesion Proteins, 2nd ed., (Kreis T, and Vale R, eds). 1999; 380-408.
  195. Olsen, BR. . Developmental biology of the skeletal system. Portland Bone Symposium. 1999; 43-56.
  196. Karttunen, L, Vikkula, M, Boon, LM, Olsen, BR. . TIE-2 signalling and venous malformations. Angiogenesis in Health and Disease. Basic Mechanisms and Clinical Applications. (Rubanyi, GM. ed.). 1999; 89-96.
  197. Olsen, BR. . Developmental biology of the skeletal system. Portland Bone Symposium. 1999; 43-56.
  198. Olsen B. [Jevgenij Botkin--personal physician of the tzar--an obituary 80 years after his death]. Tidsskr Nor Laegeforen. 1998 Dec 10; 118(30):4697-9. PMID: 9914756.
    View in: PubMed
  199. Yu J, Madison JM, Mundlos S, Winston F, Olsen BR. Characterization of a human homologue of the Saccharomyces cerevisiae transcription factor spt3 (SUPT3H). Genomics. 1998 Oct 01; 53(1):90-6. PMID: 9787080.
    View in: PubMed
  200. Gorski JP, Olsen BR. Mutations in extracellular matrix molecules. Curr Opin Cell Biol. 1998 Oct; 10(5):586-93. PMID: 9818168.
    View in: PubMed
  201. Vikkula M, Boon LM, Mulliken JB, Olsen BR. Molecular basis of vascular anomalies. Trends Cardiovasc Med. 1998 Oct; 8(7):281-92. PMID: 14987552.
    View in: PubMed
  202. Olsen B. [Refugee or immigrant children in hospital]. Tidsskr Nor Laegeforen. 1998 Sep 30; 118(23):3585-8. PMID: 9820001.
    View in: PubMed
  203. Jüppner H, Schipani E, Bastepe M, Cole DE, Lawson ML, Mannstadt M, Hendy GN, Plotkin H, Koshiyama H, Koh T, Crawford JD, Olsen BR, Vikkula M. The gene responsible for pseudohypoparathyroidism type Ib is paternally imprinted and maps in four unrelated kindreds to chromosome 20q13.3. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11798-803. PMID: 9751745; PMCID: PMC21720.
  204. Thomas CE, Olsen B, Elkins C. Cloning and characterization of tdhA, a locus encoding a TonB-dependent heme receptor from Haemophilus ducreyi. Infect Immun. 1998 Sep; 66(9):4254-62. PMID: 9712775; PMCID: PMC108513.
  205. Sasaki T, Fukai N, Mann K, Göhring W, Olsen BR, Timpl R. Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin. EMBO J. 1998 Aug 03; 17(15):4249-56. PMID: 9687493; PMCID: PMC1170758.
  206. Olsen BR. "A rare disorder, yes; an unimportant one, never". J Clin Invest. 1998 Apr 15; 101(8):1545-6. PMID: 9541481; PMCID: PMC508732.
  207. Hohenester E, Sasaki T, Olsen BR, Timpl R. Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution. EMBO J. 1998 Mar 16; 17(6):1656-64. PMID: 9501087; PMCID: PMC1170513.
  208. Olsen B. [Health and inequality--is the time of our innocence over?]. Tidsskr Nor Laegeforen. 1998 Jan 10; 118(1):13. PMID: 9481902.
    View in: PubMed
  209. Ninomiya, Y, Olsen, BR, Ooyama, T. (eds) . Extracellular Matrix-Cell Interaction. Molecules to Diseases. 1998.
  210. Apte, SS, Olsen, BR. . Collagen gene mutations and impaired skeletal development. Skeletal Growth and Development (Buckwalter et al. eds). 1998.
  211. Elkins C, Totten PA, Olsen B, Thomas CE. Role of the Haemophilus ducreyi Ton system in internalization of heme from hemoglobin. Infect Immun. 1998 Jan; 66(1):151-60. PMID: 9423852; PMCID: PMC107871.
  212. Olsen, BR. . Genetic analysis of skeletal and vascular morphogenesis. Connective Tissue Biology. Integration and Reductionism. (RK Reed, K Rubin, ed.). 1998; 9-16.
  213. Olsen B. [Murderers in white coats--the physicians' plot against Stalin]. Tidsskr Nor Laegeforen. 1997 Dec 10; 117(30):4395-8. PMID: 9456584.
    View in: PubMed
  214. Fülöp C, Kamath RV, Li Y, Otto JM, Salustri A, Olsen BR, Glant TT, Hascall VC. Coding sequence, exon-intron structure and chromosomal localization of murine TNF-stimulated gene 6 that is specifically expressed by expanding cumulus cell-oocyte complexes. Gene. 1997 Nov 20; 202(1-2):95-102. PMID: 9427551.
    View in: PubMed
  215. Olsen B. [Changing physician's role]. Tidsskr Nor Laegeforen. 1997 Oct 20; 117(25):3631-2. PMID: 9417652.
    View in: PubMed
  216. Apte SS, Fukai N, Beier DR, Olsen BR. The matrix metalloproteinase-14 (MMP-14) gene is structurally distinct from other MMP genes and is co-expressed with the TIMP-2 gene during mouse embryogenesis. J Biol Chem. 1997 Oct 10; 272(41):25511-7. PMID: 9325265.
    View in: PubMed
  217. Olsen B. [HIV epidemic in Russia]. Tidsskr Nor Laegeforen. 1997 Sep 10; 117(21):3064. PMID: 9381436.
    View in: PubMed
  218. Huang LF, Fukai N, Selby PB, Olsen BR, Mundlos S. Mouse clavicular development: analysis of wild-type and cleidocranial dysplasia mutant mice. Dev Dyn. 1997 Sep; 210(1):33-40. PMID: 9286593.
    View in: PubMed
  219. Goodman FR, Mundlos S, Muragaki Y, Donnai D, Giovannucci-Uzielli ML, Lapi E, Majewski F, McGaughran J, McKeown C, Reardon W, Upton J, Winter RM, Olsen BR, Scambler PJ. Synpolydactyly phenotypes correlate with size of expansions in HOXD13 polyalanine tract. Proc Natl Acad Sci U S A. 1997 Jul 08; 94(14):7458-63. PMID: 9207113; PMCID: PMC23843.
  220. Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, Albright S, Lindhout D, Cole WG, Henn W, Knoll JH, Owen MJ, Mertelsmann R, Zabel BU, Olsen BR. Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell. 1997 May 30; 89(5):773-9. PMID: 9182765.
    View in: PubMed
  221. Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell. 1997 May 30; 89(5):765-71. PMID: 9182764.
    View in: PubMed
  222. Li Y, Olsen BR. Murine models of human genetic skeletal disorders. Matrix Biol. 1997 May; 16(2):49-52. PMID: 9205941.
    View in: PubMed
  223. Weed M, Mundlos S, Olsen BR. The role of sonic hedgehog in vertebrate development. Matrix Biol. 1997 May; 16(2):53-8. PMID: 9205942.
    View in: PubMed
  224. Gerecke DR, Olson PF, Koch M, Knoll JH, Taylor R, Hudson DL, Champliaud MF, Olsen BR, Burgeson RE. Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13. Genomics. 1997 Apr 15; 41(2):236-42. PMID: 9143499.
    View in: PubMed
  225. Olsen BR. Collagen IX. Int J Biochem Cell Biol. 1997 Apr; 29(4):555-8. PMID: 9363632.
    View in: PubMed
  226. Chung KS, Jacenko O, Boyle P, Olsen BR, Nishimura I. Craniofacial abnormalities in mice carrying a dominant interference mutation in type X collagen. Dev Dyn. 1997 Apr; 208(4):544-52. PMID: 9097026.
    View in: PubMed
  227. Anand-Apte B, Pepper MS, Voest E, Montesano R, Olsen B, Murphy G, Apte SS, Zetter B. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3. Invest Ophthalmol Vis Sci. 1997 Apr; 38(5):817-23. PMID: 9112976.
    View in: PubMed
  228. Mundlos S, Olsen BR. Heritable diseases of the skeleton. Part II: Molecular insights into skeletal development-matrix components and their homeostasis. FASEB J. 1997 Mar; 11(4):227-33. PMID: 9068611.
    View in: PubMed
  229. Mattei MG, Roeckel N, Olsen BR, Apte SS. Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively. Genomics. 1997 Feb 15; 40(1):168-9. PMID: 9070935.
    View in: PubMed
  230. Mundlos S, Olsen BR. Heritable diseases of the skeleton. Part I: Molecular insights into skeletal development-transcription factors and signaling pathways. FASEB J. 1997 Feb; 11(2):125-32. PMID: 9039954.
    View in: PubMed
  231. Kwan KM, Pang MK, Zhou S, Cowan SK, Kong RY, Pfordte T, Olsen BR, Sillence DO, Tam PP, Cheah KS. Abnormal compartmentalization of cartilage matrix components in mice lacking collagen X: implications for function. J Cell Biol. 1997 Jan 27; 136(2):459-71. PMID: 9015315; PMCID: PMC2134813.
  232. O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E, Birkhead JR, Olsen BR, Folkman J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell. 1997 Jan 24; 88(2):277-85. PMID: 9008168.
    View in: PubMed
  233. Pace JM, Li Y, Seegmiller RE, Teuscher C, Taylor BA, Olsen BR. Disproportionate micromelia (Dmm) in mice caused by a mutation in the C-propeptide coding region of Col2a1. Dev Dyn. 1997 Jan; 208(1):25-33. PMID: 8989518.
    View in: PubMed
  234. Fariss RN, Apte SS, Olsen BR, Iwata K, Milam AH. Tissue inhibitor of metalloproteinases-3 is a component of Bruch's membrane of the eye. Am J Pathol. 1997 Jan; 150(1):323-8. PMID: 9006347; PMCID: PMC1858531.
  235. Vikkula M, Boon LM, Carraway KL, Calvert JT, Diamonti AJ, Goumnerov B, Pasyk KA, Marchuk DA, Warman ML, Cantley LC, Mulliken JB, Olsen BR. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell. 1996 Dec 27; 87(7):1181-90. PMID: 8980225.
    View in: PubMed
  236. Sakai LY, Burgeson RE, Olsen BR, Rowe DW, Gordon SL. Current knowledge and research directions in heritable disorders of connective tissue. Matrix Biol. 1996 Sep; 15(4):211-29. PMID: 8892222.
    View in: PubMed
  237. Paschalis EP, Jacenko O, Olsen B, Mendelsohn R, Boskey AL. Fourier transform infrared microspectroscopic analysis identifies alterations in mineral properties in bones from mice transgenic for type X collagen. Bone. 1996 Aug; 19(2):151-6. PMID: 8853859.
    View in: PubMed
  238. Vikkula M, Olsen BR. Unravelling the molecular genetics of osteoarthrosis. Ann Med. 1996 Aug; 28(4):301-4. PMID: 8862683.
    View in: PubMed
  239. Gong Y, Vikkula M, Boon L, Liu J, Beighton P, Ramesar R, Peltonen L, Somer H, Hirose T, Dallapiccola B, De Paepe A, Swoboda W, Zabel B, Superti-Furga A, Steinmann B, Brunner HG, Jans A, Boles RG, Adkins W, van den Boogaard MJ, Olsen BR, Warman ML. Osteoporosis-pseudoglioma syndrome, a disorder affecting skeletal strength and vision, is assigned to chromosome region 11q12-13. Am J Hum Genet. 1996 Jul; 59(1):146-51. PMID: 8659519; PMCID: PMC1915094.
  240. Muragaki Y, Mariman EC, van Beersum SE, Perälä M, van Mourik JB, Warman ML, Hamel BC, Olsen BR. A mutation in COL9A2 causes multiple epiphyseal dysplasia (EDM2). Ann N Y Acad Sci. 1996 Jun 08; 785:303-6. PMID: 8702162.
    View in: PubMed
  241. Olsen BR. Role of cartilage collagens in formation of the skeleton. Ann N Y Acad Sci. 1996 Jun 08; 785:124-30. PMID: 8702118.
    View in: PubMed
  242. Mundlos S, Huang LF, Selby P, Olsen BR. Cleidocranial dysplasia in mice. Ann N Y Acad Sci. 1996 Jun 08; 785:301-2. PMID: 8702161.
    View in: PubMed
  243. Jacenko O, Ito S, Olsen BR. Skeletal and hematopoietic defects in mice transgenic for collagen X. Ann N Y Acad Sci. 1996 Jun 08; 785:278-80. PMID: 8702154.
    View in: PubMed
  244. Olsen B, Gylfe A, Bergström S. Canary finches (Serinus canaria) as an avian infection model for Lyme borreliosis. Microb Pathog. 1996 Jun; 20(6):319-24. PMID: 8831827.
    View in: PubMed
  245. Olsen BR. Morphogenesis: collagen it takes and bone it makes. Curr Biol. 1996 Jun 01; 6(6):645-7. PMID: 8793283.
    View in: PubMed
  246. Muragaki Y, Mundlos S, Upton J, Olsen BR. Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13. Science. 1996 Apr 26; 272(5261):548-51. PMID: 8614804.
    View in: PubMed
  247. Apte SS, Olsen BR, Murphy G. The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J Biol Chem. 1996 Feb 02; 271(5):2874. PMID: 8576269.
    View in: PubMed
  248. Paschalis EP, Jacenko O, Olsen B, deCrombrugghe B, Boskey AL. The role of type X collagen in endochondral ossification as deduced by Fourier transform infrared microscopy analysis. Connect Tissue Res. 1996; 35(1-4):371-7. PMID: 9084677.
    View in: PubMed
  249. Anand-Apte B, Bao L, Smith R, Iwata K, Olsen BR, Zetter B, Apte SS. A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth. Biochem Cell Biol. 1996; 74(6):853-62. PMID: 9164653.
    View in: PubMed
  250. Olsen, BR. , New York. Skeletal system. McGraw-Hill 1997 Yearbook of Science and Technology. 1996; 413-415.
  251. Muragaki Y, Mariman EC, van Beersum SE, Perälä M, van Mourik JB, Warman ML, Olsen BR, Hamel BC. A mutation in the gene encoding the alpha 2 chain of the fibril-associated collagen IX, COL9A2, causes multiple epiphyseal dysplasia (EDM2). Nat Genet. 1996 Jan; 12(1):103-5. PMID: 8528240.
    View in: PubMed
  252. Olsen, BR. . Matrix molecules and their ligands. Principles of Tissue Engineering. R.G. (Lanza, R, Langer, R, and Chick, W. ed). 1996; 47-65.
  253. Olsen B. [Mikhail Bulgakov--a colleague and cult figure]. Tidsskr Nor Laegeforen. 1995 Dec 10; 115(30):3784-7. PMID: 8539752.
    View in: PubMed
  254. Olsen B, Duffy DC, Jaenson TG, Gylfe A, Bonnedahl J, Bergström S. Transhemispheric exchange of Lyme disease spirochetes by seabirds. J Clin Microbiol. 1995 Dec; 33(12):3270-4. PMID: 8586715; PMCID: PMC228686.
  255. Böhme K, Li Y, Oh PS, Olsen BR. Primary structure of the long and short splice variants of mouse collagen XII and their tissue-specific expression during embryonic development. Dev Dyn. 1995 Dec; 204(4):432-45. PMID: 8601036.
    View in: PubMed
  256. Brewton RG, Wood BM, Ren ZX, Gong Y, Tiller GE, Warman ML, Lee B, Horton WA, Olsen BR, Baker JR, et al. Molecular cloning of the alpha 3 chain of human type IX collagen: linkage of the gene COL9A3 to chromosome 20q13.3. Genomics. 1995 Nov 20; 30(2):329-36. PMID: 8586434.
    View in: PubMed
  257. Wick M, Härönen R, Mumberg D, Bürger C, Olsen BR, Budarf ML, Apte SS, Müller R. Structure of the human TIMP-3 gene and its cell cycle-regulated promoter. Biochem J. 1995 Oct 15; 311 ( Pt 2):549-54. PMID: 7487894; PMCID: PMC1136034.
  258. Olsen BR. New insights into the function of collagens from genetic analysis. Curr Opin Cell Biol. 1995 Oct; 7(5):720-7. PMID: 8573348.
    View in: PubMed
  259. Muragaki Y, Timmons S, Griffith CM, Oh SP, Fadel B, Quertermous T, Olsen BR. Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8763-7. PMID: 7568013; PMCID: PMC41047.
  260. Austveg B, Olsen B. [Diseases of the poor. Anniversary of the WHO tropical disease research project]. Tidsskr Nor Laegeforen. 1995 Sep 10; 115(21):2633-4. PMID: 7570469.
    View in: PubMed
  261. Melsom H, Hannisdal E, Olsen B. [Registry-based quality development in health care]. Tidsskr Nor Laegeforen. 1995 Aug 10; 115(18):2234-5. PMID: 7652717.
    View in: PubMed
  262. Olsen BR. Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias. Bone. 1995 Aug; 17(2 Suppl):45S-49S. PMID: 8579897.
    View in: PubMed
  263. Haimes HB, Jimenez PA, Li Y, Shinya T, Olsen BR. Overexpression of the NC4 domain of type IX collagen induces osteoarthritis in mice. Inflamm Res. 1995 Aug; 44 Suppl 2:S127-8. PMID: 8548361.
    View in: PubMed
  264. Mallein-Gerin F, Ruggiero F, Quinn TM, Bard F, Grodzinsky AJ, Olsen BR, van der Rest M. Analysis of collagen synthesis and assembly in culture by immortalized mouse chondrocytes in the presence or absence of alpha 1(IX) collagen chains. Exp Cell Res. 1995 Jul; 219(1):257-65. PMID: 7628541.
    View in: PubMed
  265. Apte SS, Olsen BR, Murphy G. The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J Biol Chem. 1995 Jun 16; 270(24):14313-8. PMID: 7782289.
    View in: PubMed
  266. Olsen B. [Increased governmental steering of health services]. Tidsskr Nor Laegeforen. 1995 Jun 10; 115(15):1820. PMID: 7638827.
    View in: PubMed
  267. Apte SS, Mattei MG, Seldin MF, Olsen BR. The highly conserved defender against the death 1 (DAD1) gene maps to human chromosome 14q11-q12 and mouse chromosome 14 and has plant and nematode homologs. FEBS Lett. 1995 Apr 24; 363(3):304-6. PMID: 7737422.
    View in: PubMed
  268. Apte SS, Mattei MG, Olsen BR. Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta. Genomics. 1995 Apr 10; 26(3):592-4. PMID: 7607685.
    View in: PubMed
  269. Reponen P, Leivo I, Sahlberg C, Apte SS, Olsen BR, Thesleff I, Tryggvason K. 92-kDa type IV collagenase and TIMP-3, but not 72-kDa type IV collagenase or TIMP-1 or TIMP-2, are highly expressed during mouse embryo implantation. Dev Dyn. 1995 Apr; 202(4):388-96. PMID: 7626795.
    View in: PubMed
  270. Olsen BR. The roles of collagen genes in skeletal development and morphogenesis. Experientia. 1995 Mar 15; 51(3):194-5. PMID: 7698270.
    View in: PubMed
  271. Jacenko O, Olsen BR. Transgenic mouse models in studies of skeletal disorders. J Rheumatol Suppl. 1995 Feb; 43:39-41. PMID: 7752133.
    View in: PubMed
  272. Mundlos S, Mulliken JB, Abramson DL, Warman ML, Knoll JH, Olsen BR. Genetic mapping of cleidocranial dysplasia and evidence of a microdeletion in one family. Hum Mol Genet. 1995 Jan; 4(1):71-5. PMID: 7711736.
    View in: PubMed
  273. Radovick S, Wray S, Muglia L, Westphal H, Olsen B, Smith E, Patriquin E, Wondisford FE. Steroid hormone regulation and tissue-specific expression of the human GnRH gene in cell culture and transgenic animals. Horm Behav. 1994 Dec; 28(4):520-9. PMID: 7729821.
    View in: PubMed
  274. Zieske JD, Mason VS, Wasson ME, Meunier SF, Nolte CJ, Fukai N, Olsen BR, Parenteau NL. Basement membrane assembly and differentiation of cultured corneal cells: importance of culture environment and endothelial cell interaction. Exp Cell Res. 1994 Oct; 214(2):621-33. PMID: 7523155.
    View in: PubMed
  275. Boon LM, Mulliken JB, Vikkula M, Watkins H, Seidman J, Olsen BR, Warman ML. Assignment of a locus for dominantly inherited venous malformations to chromosome 9p. Hum Mol Genet. 1994 Sep; 3(9):1583-7. PMID: 7833915.
    View in: PubMed
  276. Warman ML, McCarthy MT, Perälä M, Vuorio E, Knoll JH, McDaniels CN, Mayne R, Beier DR, Olsen BR. The genes encoding alpha 2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4. Genomics. 1994 Sep 01; 23(1):158-62. PMID: 7829066.
    View in: PubMed
  277. Brunner HG, van Beersum SE, Warman ML, Olsen BR, Ropers HH, Mariman EC. A Stickler syndrome gene is linked to chromosome 6 near the COL11A2 gene. Hum Mol Genet. 1994 Sep; 3(9):1561-4. PMID: 7833911.
    View in: PubMed
  278. Apte SS, Hayashi K, Seldin MF, Mattei MG, Hayashi M, Olsen BR. Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10. Dev Dyn. 1994 Jul; 200(3):177-97. PMID: 7949367.
    View in: PubMed
  279. Fässler R, Schnegelsberg PN, Dausman J, Shinya T, Muragaki Y, McCarthy MT, Olsen BR, Jaenisch R. Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):5070-4. PMID: 8197187; PMCID: PMC43933.
  280. Olsen B, Johansen TE. [Urinary bladder diverticula]. Tidsskr Nor Laegeforen. 1994 May 10; 114(12):1411-3. PMID: 8079226.
    View in: PubMed
  281. Oh SP, Kamagata Y, Muragaki Y, Timmons S, Ooshima A, Olsen BR. Isolation and sequencing of cDNAs for proteins with multiple domains of Gly-Xaa-Yaa repeats identify a distinct family of collagenous proteins. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4229-33. PMID: 8183893; PMCID: PMC43758.
  282. Rimoin DL, Rasmussen IM, Briggs MD, Roughley PJ, Gruber HE, Warman ML, Olsen BR, Hsia YE, Yuen J, Reinker K, et al. A large family with features of pseudoachondroplasia and multiple epiphyseal dysplasia: exclusion of seven candidate gene loci that encode proteins of the cartilage extracellular matrix. Hum Genet. 1994 Mar; 93(3):236-42. PMID: 7907311.
    View in: PubMed
  283. Muragaki Y, Abe N, Ninomiya Y, Olsen BR, Ooshima A. The human alpha 1(XV) collagen chain contains a large amino-terminal non-triple helical domain with a tandem repeat structure and homology to alpha 1(XVIII) collagen. J Biol Chem. 1994 Feb 11; 269(6):4042-6. PMID: 8307960.
    View in: PubMed
  284. Jacenko O, Olsen BR, Warman ML. Of mice and men: heritable skeletal disorders. Am J Hum Genet. 1994 Feb; 54(2):163-8. PMID: 8304335; PMCID: PMC1918165.
  285. Oh SP, Warman ML, Seldin MF, Cheng SD, Knoll JH, Timmons S, Olsen BR. Cloning of cDNA and genomic DNA encoding human type XVIII collagen and localization of the alpha 1(XVIII) collagen gene to mouse chromosome 10 and human chromosome 21. Genomics. 1994 Feb; 19(3):494-9. PMID: 8188291.
    View in: PubMed
  286. McIntosh I, Abbott MH, Warman ML, Olsen BR, Francomano CA. Additional mutations of type X collagen confirm COL10A1 as the Schmid metaphyseal chondrodysplasia locus. Hum Mol Genet. 1994 Feb; 3(2):303-7. PMID: 8004099.
    View in: PubMed
  287. Apte SS, Mattei MG, Olsen BR. Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22. Genomics. 1994 Jan 01; 19(1):86-90. PMID: 8188246.
    View in: PubMed
  288. Rokos I, Muragaki Y, Warman M, Olsen BR. Assembly and sequencing of a cDNA covering the entire mouse alpha 1(IX) collagen chain. Matrix Biol. 1994 Jan; 14(1):1-8. PMID: 8061915.
    View in: PubMed
  289. Fukai N, Apte SS, and Olsen BR. . Non-fibrillar collagens. Methods in Enzymology (Engvall E, Ruoslahti E, eds). 1994; 1-28.
  290. Olsen BR, and McCarthy, M. , , 1994;pp.38-63. Molecular structure of the sclera, cornea, and vitreous body. Principles and Practice of Ophthalmology (Albert DM, and Jakobiec FA, eds). 1994; 38-63.
  291. Fukai N, Apte SS, Olsen BR. Nonfibrillar collagens. Methods Enzymol. 1994; 245:3-28. PMID: 7760741.
    View in: PubMed
  292. Olsen B. [Russia is not a country, not a nation, but a thousand years old disease]. Tidsskr Nor Laegeforen. 1993 Oct 20; 113(25):3167-9. PMID: 8273051.
    View in: PubMed
  293. Liu CY, Olsen BR, Kao WW. Developmental patterns of two alpha 1(IX) collagen mRNA isoforms in mouse. Dev Dyn. 1993 Oct; 198(2):150-7. PMID: 8305707.
    View in: PubMed
  294. Jacenko O, LuValle PA, Olsen BR. Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition. Nature. 1993 Sep 02; 365(6441):56-61. PMID: 8361538.
    View in: PubMed
  295. Warman ML, Abbott M, Apte SS, Hefferon T, McIntosh I, Cohn DH, Hecht JT, Olsen BR, Francomano CA. A type X collagen mutation causes Schmid metaphyseal chondrodysplasia. Nat Genet. 1993 Sep; 5(1):79-82. PMID: 8220429.
    View in: PubMed
  296. Warman ML, Tiller GE, Polumbo PA, Seldin MF, Rochelle JM, Knoll JH, Cheng SD, Olsen BR. Physical and linkage mapping of the human and murine genes for the alpha 1 chain of type IX collagen (COL9A1). Genomics. 1993 Sep; 17(3):694-8. PMID: 8244386.
    View in: PubMed
  297. Olsen B, Johansen TE, Majak BM. [Cystitis cystica--a premalignant condition?]. Tidsskr Nor Laegeforen. 1993 Aug 10; 113(18):2255-6. PMID: 8362391.
    View in: PubMed
  298. Guldberg P, Lou HC, Henriksen KF, Mikkelsen I, Olsen B, Holck B, Güttler F. A novel missense mutation in the phenylalanine hydroxylase gene of a homozygous Pakistani patient with non-PKU hyperphenylalaninemia. Hum Mol Genet. 1993 Jul; 2(7):1061-2. PMID: 8364546.
    View in: PubMed
  299. Olsen B, Fylkesnes K. [The health survey in Finnmark--satisfaction with hospital services]. Tidsskr Nor Laegeforen. 1993 Jun 30; 113(17):2081-4. PMID: 8337664.
    View in: PubMed
  300. Gerecke DR, Foley JW, Castagnola P, Gennari M, Dublet B, Cancedda R, Linsenmayer TF, van der Rest M, Olsen BR, Gordon MK. Type XIV collagen is encoded by alternative transcripts with distinct 5' regions and is a multidomain protein with homologies to von Willebrand's factor, fibronectin, and other matrix proteins. J Biol Chem. 1993 Jun 05; 268(16):12177-84. PMID: 8505337.
    View in: PubMed
  301. Lu Valle P, Iwamoto M, Fanning P, Pacifici M, Olsen BR. Multiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes. J Cell Biol. 1993 Jun; 121(5):1173-9. PMID: 8501122; PMCID: PMC2119691.
  302. Rosenblum ND, Briscoe DM, Karnovsky MJ, Olsen BR. Alpha 1-VIII collagen is expressed in the rat glomerulus and in resident glomerular cells. Am J Physiol. 1993 Jun; 264(6 Pt 2):F1003-10. PMID: 8322888.
    View in: PubMed
  303. Iwamoto M, Yagami K, Lu Valle P, Olsen BR, Petropoulos CJ, Ewert DL, Pacifici M. Expression and role of c-myc in chondrocytes undergoing endochondral ossification. J Biol Chem. 1993 May 05; 268(13):9645-52. PMID: 8486652.
    View in: PubMed
  304. Mallein-Gerin F, Olsen BR. Expression of simian virus 40 large T (tumor) oncogene in mouse chondrocytes induces cell proliferation without loss of the differentiated phenotype. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3289-93. PMID: 7682698; PMCID: PMC46285.
  305. Nakata K, Ono K, Miyazaki J, Olsen BR, Muragaki Y, Adachi E, Yamamura K, Kimura T. Osteoarthritis associated with mild chondrodysplasia in transgenic mice expressing alpha 1(IX) collagen chains with a central deletion. Proc Natl Acad Sci U S A. 1993 Apr 01; 90(7):2870-4. PMID: 8464901; PMCID: PMC46198.
  306. Warman M, Kimura T, Muragaki Y, Castagnola P, Tamei H, Iwata K, Olsen BR. Monoclonal antibodies against two epitopes in the human alpha 1 (IX) collagen chain. Matrix. 1993 Mar; 13(2):149-56. PMID: 7684111.
    View in: PubMed
  307. Apte SS, Olsen BR. Characterization of the mouse type X collagen gene. Matrix. 1993 Mar; 13(2):165-79. PMID: 8492743.
    View in: PubMed
  308. Ninomiya Y, and Olsen BR. . Facit collagens (types IX, XII, XIV). Guidebook to the Extracellular Matrix and Adhesion Proteins (Kreis T, and Vale R, eds). 1993; 37-40.
  309. LuValle P, Jacenko O, Iwamoto M, Pacifici M, and Olsen BR. . From cartilage to bone -the role of collagenous proteins. Molecular Basis of Morphogenesis (Bernfield M, ed), 51st Annual Symposium of the Society for Developmental Biology. 1993; 189-205.
  310. Jacenko O, LuValle P, Solum K, and Olsen BR. . A dominant negative mutation in the a1(X) collagen gene produces spondylometaphyseal defects in mice. Proceedings of the Fourth International Congress on Limb Development and Regeneration, (Fallon J, Goetinck P, Kelley R, and Stocum D, eds). 1993; 427-436.
  311. Olsen BR, LuValle PA, Jacenko O. . Role of non-fibrillar collagens in matrix assemblies. Tissue Engineering: Current perspectives (Bell E, ed.). 1993; 19-25.
  312. Jacenko O, LuValle P, Solum K, Olsen BR. A dominant negative mutation in the alpha 1 (X) collagen gene produces spondylometaphyseal defects in mice. Prog Clin Biol Res. 1993; 383B:427-36. PMID: 8115362.
    View in: PubMed
  313. Oh SP, Griffith CM, Hay ED, Olsen BR. Tissue-specific expression of type XII collagen during mouse embryonic development. Dev Dyn. 1993 Jan; 196(1):37-46. PMID: 8334298.
    View in: PubMed
  314. Castagnola P, Tavella S, Gerecke DR, Dublet B, Gordon MK, Seyer J, Cancedda R, van der Rest M, Olsen BR. Tissue-specific expression of type XIV collagen--a member of the FACIT class of collagens. Eur J Cell Biol. 1992 Dec; 59(2):340-7. PMID: 1493799.
    View in: PubMed
  315. LuValle P, Daniels K, Hay ED, Olsen BR. Type X collagen is transcriptionally activated and specifically localized during sternal cartilage maturation. Matrix. 1992 Nov; 12(5):404-13. PMID: 1484507.
    View in: PubMed
  316. Reichenberger E, Beier F, LuValle P, Olsen BR, von der Mark K, Bertling WM. Genomic organization and full-length cDNA sequence of human collagen X. FEBS Lett. 1992 Oct 26; 311(3):305-10. PMID: 1397333.
    View in: PubMed
  317. García-Cimbrelo E, Olsen B, Ruiz-Yagüe M, Fernandez-Baíllo N, Munuera-Martínez L. Ilizarov technique. Results and difficulties. Clin Orthop Relat Res. 1992 Oct; (283):116-23. PMID: 1395234.
    View in: PubMed
  318. Oh SP, Taylor RW, Gerecke DR, Rochelle JM, Seldin MF, Olsen BR. The mouse alpha 1(XII) and human alpha 1(XII)-like collagen genes are localized on mouse chromosome 9 and human chromosome 6. Genomics. 1992 Oct; 14(2):225-31. PMID: 1427837.
    View in: PubMed
  319. Peterson MB, Frantzen M, Antonarakis SE, Warren AC, Van Broeckhoven C, Chakravarti A, Cox TK, Lund C, Olsen B, Poulsen H, et al. Comparative study of microsatellite and cytogenetic markers for detecting the origin of the nondisjoined chromosome 21 in Down syndrome. Am J Hum Genet. 1992 Sep; 51(3):516-25. PMID: 1386710; PMCID: PMC1682728.
  320. Muragaki Y, Shiota C, Inoue M, Ooshima A, Olsen BR, Ninomiya Y. alpha 1(VIII)-collagen gene transcripts encode a short-chain collagen polypeptide and are expressed by various epithelial, endothelial and mesenchymal cells in newborn mouse tissues. Eur J Biochem. 1992 Aug 01; 207(3):895-902. PMID: 1499564.
    View in: PubMed
  321. Apte SS, Seldin MF, Hayashi M, Olsen BR. Cloning of the human and mouse type X collagen genes and mapping of the mouse type X collagen gene to chromosome 10. Eur J Biochem. 1992 May 15; 206(1):217-24. PMID: 1587271.
    View in: PubMed
  322. Olsen BR. . Molecular biology of cartilage collagens. Articular Cartilage and Osteoarthritis (Kuettner K and Schleyerbach R, eds). 1992; 151-166.
  323. Gordon MK, Castagnola P, Dublet B, Linsenmayer TF, Van der Rest M, Mayne R, Olsen BR. Cloning of a cDNA for a new member of the class of fibril-associated collagens with interrupted triple helices. Eur J Biochem. 1991 Oct 15; 201(2):333-8. PMID: 1935930.
    View in: PubMed
  324. Olsen B, Lotsberg J, Dyrkorn K, Skreosen A, Vegrim M. [Small hospitals--future tasks and functions]. Tidsskr Nor Laegeforen. 1991 Jun 30; 111(17):2170. PMID: 1871757.
    View in: PubMed
  325. Muragaki Y, Mattei MG, Yamaguchi N, Olsen BR, Ninomiya Y. The complete primary structure of the human alpha 1 (VIII) chain and assignment of its gene (COL8A1) to chromosome 3. Eur J Biochem. 1991 May 08; 197(3):615-22. PMID: 2029894.
    View in: PubMed
  326. Apte S, Mattei MG, Olsen BR. Cloning of human alpha 1(X) collagen DNA and localization of the COL10A1 gene to the q21-q22 region of human chromosome 6. FEBS Lett. 1991 May 06; 282(2):393-6. PMID: 2037056.
    View in: PubMed
  327. Shaw LM, Olsen BR. FACIT collagens: diverse molecular bridges in extracellular matrices. Trends Biochem Sci. 1991 May; 16(5):191-4. PMID: 1882421.
    View in: PubMed
  328. Olsen B, Fylkesnes K. [The health survey in Finnmark--how is the population satisfied with community health services?]. Tidsskr Nor Laegeforen. 1991 Apr 30; 111(11):1385-9. PMID: 2042164.
    View in: PubMed
  329. Muragaki Y, Jacenko O, Apte S, Mattei MG, Ninomiya Y, Olsen BR. The alpha 2(VIII) collagen gene. A novel member of the short chain collagen family located on the human chromosome 1. J Biol Chem. 1991 Apr 25; 266(12):7721-7. PMID: 2019595.
    View in: PubMed
  330. Iyama K, Ninomiya Y, Olsen BR, Linsenmayer TF, Trelstad RL, Hayashi M. Spatiotemporal pattern of type X collagen gene expression and collagen deposition in embryonic chick vertebrae undergoing endochondral ossification. Anat Rec. 1991 Apr; 229(4):462-72. PMID: 2048750.
    View in: PubMed
  331. Upholt WB and Olsen BR. . The active genes of cartilage. Cartilage: Molecular Aspects, (Hall BK and Newman SA, eds). 1991; 1-57.
  332. Jacenko O, Olsen BR, LuValle P. Organization and regulation of collagen genes. Crit Rev Eukaryot Gene Expr. 1991; 1(4):327-53. PMID: 1802113.
    View in: PubMed
  333. Jacenko O, Olsen BR, and LuValle P. . Organization and regulation of collagen genes. Critical Reviews in Eukaryotic Gene Expression, Vol. I (Stein GS, Stein JL, and Lian JB, eds). 1991; 327-353.
  334. Olsen BR. . Collagen biosynthesis. Cell Biology of Extracellular Matrix (Hay ED, ed). 1991; 177-220.
  335. Nakahara H, Watanabe K, Sugrue SP, Olsen BR, Caplan AI. Temporal and spatial distribution of type XII collagen in high cell density culture of periosteal-derived cells. Dev Biol. 1990 Dec; 142(2):481-5. PMID: 1701739.
    View in: PubMed
  336. Rosenblum ND, Karnovsky MJ, Olsen BR. Non-fibrillar collagenous proteins synthesized by rat mesangial cells. J Am Soc Nephrol. 1990 Nov; 1(5):785-91. PMID: 2133427.
    View in: PubMed
  337. Gordon MK, Olsen BR. The contribution of collagenous proteins to tissue-specific matrix assemblies. Curr Opin Cell Biol. 1990 Oct; 2(5):833-8. PMID: 2083084.
    View in: PubMed
  338. Muragaki Y, Kimura T, Ninomiya Y, Olsen BR. The complete primary structure of two distinct forms of human alpha 1 (IX) collagen chains. Eur J Biochem. 1990 Sep 24; 192(3):703-8. PMID: 2209617.
    View in: PubMed
  339. Hoffart A, Bille H, Olsen B, Gude T, Mygind-Klausen O, Gilje B, Rolie JP, Thornes K. [Institutionalized treatment of agoraphobia with panic anxiety]. Tidsskr Nor Laegeforen. 1990 Sep 20; 110(22):2889-92. PMID: 2219069.
    View in: PubMed
  340. Olsen B. [Mammon's realm or Pluto's reign--is it commercialism or random decisions that determines the distribution of physicians?]. Tidsskr Nor Laegeforen. 1990 Jun 30; 110(17):2182-3. PMID: 2375009.
    View in: PubMed
  341. Muragaki Y, Nishimura I, Henney A, Ninomiya Y, Olsen BR. The alpha 1 (IX) collagen gene gives rise to two different transcripts in both mouse embryonic and human fetal RNA. Proc Natl Acad Sci U S A. 1990 Apr; 87(7):2400-4. PMID: 1690886; PMCID: PMC53696.
  342. Nishimura I, Muragaki Y, Hayashi M, Ninomiya Y, Olsen BR. Tissue-specific expression of type IX collagen. Ann N Y Acad Sci. 1990; 580:112-9. PMID: 2186688.
    View in: PubMed
  343. Gordon MK, Gerecke DR, Dublet B, van der Rest M, Sugrue SP, Olsen BR. The structure of type XII collagen. Ann N Y Acad Sci. 1990; 580:8-16. PMID: 2186698.
    View in: PubMed
  344. Ninomiya Y, Castagnola P, Gerecke D, Gordon M, Jacenko O, LuValle P, McCarthy M, Muragaki Y, Nishimura I, Oh S, Rosenblum N, Sato N, Sugrue S, Taylor R, Vasios G, Yamaguchi N, Olsen BR. . The molecular biology of collagens with short triple-helical domains. Extracellular Matrix Genes, (Sandell LJ and Boyd CD, eds). 1990; 79-114.
  345. Nishimura I, Muragaki Y, Olsen BR. Tissue-specific forms of type IX collagen-proteoglycan arise from the use of two widely separated promoters. J Biol Chem. 1989 Nov 25; 264(33):20033-41. PMID: 2584206.
    View in: PubMed
  346. Gordon MK, Gerecke DR, Dublet B, van der Rest M, Olsen BR. Type XII collagen. A large multidomain molecule with partial homology to type IX collagen. J Biol Chem. 1989 Nov 25; 264(33):19772-8. PMID: 2584192.
    View in: PubMed
  347. Olsen B. [Prevalence of urinary incontinence]. Tidsskr Nor Laegeforen. 1989 Sep 20; 109(26):2711. PMID: 2815003.
    View in: PubMed
  348. Kimura T, Cheah KS, Chan SD, Lui VC, Mattei MG, van der Rest M, Ono K, Solomon E, Ninomiya Y, Olsen BR. The human alpha 2(XI) collagen (COL11A2) chain. Molecular cloning of cDNA and genomic DNA reveals characteristics of a fibrillar collagen with differences in genomic organization. J Biol Chem. 1989 Aug 15; 264(23):13910-6. PMID: 2760050.
    View in: PubMed
  349. Dublet B, Oh S, Sugrue SP, Gordon MK, Gerecke DR, Olsen BR, van der Rest M. The structure of avian type XII collagen. Alpha 1 (XII) chains contain 190-kDa non-triple helical amino-terminal domains and form homotrimeric molecules. J Biol Chem. 1989 Aug 05; 264(22):13150-6. PMID: 2753905.
    View in: PubMed
  350. Sugrue SP, Gordon MK, Seyer J, Dublet B, van der Rest M, Olsen BR. Immunoidentification of type XII collagen in embryonic tissues. J Cell Biol. 1989 Aug; 109(2):939-45. PMID: 2668306; PMCID: PMC2115737.
  351. LuValle P, Hayashi M, Olsen BR. Transcriptional regulation of type X collagen during chondrocyte maturation. Dev Biol. 1989 Jun; 133(2):613-6. PMID: 2731643.
    View in: PubMed
  352. Kimura T, Mattei MG, Stevens JW, Goldring MB, Ninomiya Y, Olsen BR. Molecular cloning of rat and human type IX collagen cDNA and localization of the alpha 1(IX) gene on the human chromosome 6. Eur J Biochem. 1989 Jan 15; 179(1):71-8. PMID: 2465149.
    View in: PubMed
  353. Olsen BR, Gerecke D, Gordon M, Green G, Kimura T, Konomi H, Muragaki Y, Ninomiya Y, Nishimura I, Sugrue S. . A new dimension in the extracellular matrix. Collagen: Biochemistry, Biotechnology and Molecular Biology (Olsen BR, Nimni M, eds). 1989; IV:1-19.
  354. Olsen BR, Nimni M (eds.). . Collagen: Biochemistry, Biotechnology and Molecular Biology, Vol. IV. 1989.
  355. Olsen BR. The next frontier: molecular biology of extracellular matrix. Connect Tissue Res. 1989; 23(2-3):115-21. PMID: 2698312.
    View in: PubMed
  356. Gordon MK, Gerecke DR, Nishimura I, Ninomiya Y, Olsen BR. A new dimension in the extracellular matrix. Connect Tissue Res. 1989; 20(1-4):179-86. PMID: 2692954.
    View in: PubMed
  357. LuValle P, Ninomiya Y, Rosenblum ND, Olsen BR. The type X collagen gene. Intron sequences split the 5'-untranslated region and separate the coding regions for the non-collagenous amino-terminal and triple-helical domains. J Biol Chem. 1988 Dec 05; 263(34):18378-85. PMID: 2461368.
    View in: PubMed
  358. Bernard M, Yoshioka H, Rodriguez E, Van der Rest M, Kimura T, Ninomiya Y, Olsen BR, Ramirez F. Cloning and sequencing of pro-alpha 1 (XI) collagen cDNA demonstrates that type XI belongs to the fibrillar class of collagens and reveals that the expression of the gene is not restricted to cartilagenous tissue. J Biol Chem. 1988 Nov 15; 263(32):17159-66. PMID: 3182841.
    View in: PubMed
  359. Fleischmajer R, Perlish JS, Timpl R, Olsen BR. Procollagen intermediates during tendon fibrillogenesis. J Histochem Cytochem. 1988 Nov; 36(11):1425-32. PMID: 3049791.
    View in: PubMed
  360. Aarskog D, Alvik A, Asvall J, Christie F, Grund J, Hammerstad O, Harlem OK, Ivan P, Olsen B. [Physician's role in the year 2000]. Tidsskr Nor Laegeforen. 1988 Oct 25; 108(29B):2665-79. PMID: 3144055.
    View in: PubMed
  361. Svoboda KK, Nishimura I, Sugrue SP, Ninomiya Y, Olsen BR. Embryonic chicken cornea and cartilage synthesize type IX collagen molecules with different amino-terminal domains. Proc Natl Acad Sci U S A. 1988 Oct; 85(20):7496-7500. PMID: 3050996; PMCID: PMC282218.
  362. Teilum D, Olsen B. The prevalence of gallstones in autopsies from a Danish urban area. Frederiksberg, 1959-1985. Scand J Gastroenterol. 1988 Sep; 23(7):813-6. PMID: 3227296.
    View in: PubMed
  363. Henry I, Bernheim A, Bernard M, van der Rest M, Kimura T, Jeanpierre C, Barichard F, Berger R, Olsen BR, Ramirez F, et al. Mapping of a human fibrillar collagen gene, pro alpha 1 (XI) (COL11A1), to the p21 region of chromosome 1. Genomics. 1988 Jul; 3(1):87-90. PMID: 3220479.
    View in: PubMed
  364. Hayashi M, Ninomiya Y, Hayashi K, Linsenmayer TF, Olsen BR, Trelstad RL. Secretion of collagen types I and II by epithelial and endothelial cells in the developing chick cornea demonstrated by in situ hybridization and immunohistochemistry. Development. 1988 May; 103(1):27-36. PMID: 3197631.
    View in: PubMed
  365. Vasios G, Nishimura I, Konomi H, van der Rest M, Ninomiya Y, Olsen BR. Cartilage type IX collagen-proteoglycan contains a large amino-terminal globular domain encoded by multiple exons. J Biol Chem. 1988 Feb 15; 263(5):2324-9. PMID: 3339014.
    View in: PubMed
  366. Olsen BR. Molecular biology of the cartilage collagens. Pathol Immunopathol Res. 1988; 7(1-2):20-3. PMID: 3065767.
    View in: PubMed
  367. Olsen BR, Ninomiya Y. . A new generation of collagenous proteins their structure and role in extracellular matrices. The Control of Tissue Damage, (Glauert AM, ed). 1988; 29-39.
  368. Gordon MK, Gerecke DR, Olsen BR. Type XII collagen: distinct extracellular matrix component discovered by cDNA cloning. Proc Natl Acad Sci U S A. 1987 Sep; 84(17):6040-4. PMID: 3476925; PMCID: PMC299003.
  369. Fleischmajer R, Perlish JS, Olsen BR. The carboxylpropeptide of type I procollagen in skin fibrillogenesis. J Invest Dermatol. 1987 Aug; 89(2):212-5. PMID: 3298449.
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  370. McCormick D, van der Rest M, Goodship J, Lozano G, Ninomiya Y, Olsen BR. Structure of the glycosaminoglycan domain in the type IX collagen-proteoglycan. Proc Natl Acad Sci U S A. 1987 Jun; 84(12):4044-8. PMID: 3473493; PMCID: PMC305018.
  371. Vasios G, Ninomiya Y, Olsen BR. . Analysis of collagen structure by molecular biology techniques. Structure and Function of Collagen Types, (Mayne R, Burgeson RE, eds). 1987; 283-309.
  372. Fleischmajer R, Perlish JS, Olsen BR. Amino and carboxyl propeptides in bone collagen fibrils during embryogenesis. Cell Tissue Res. 1987 Jan; 247(1):105-9. PMID: 3829111.
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  373. Olsen B. [Dercum's disease (adiposis dolorosa). A forgotten entity?]. Tidsskr Nor Laegeforen. 1986 Aug 20; 106(23):1820-2. PMID: 3764857.
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  374. Van der Rest M, Rosenberg LC, Olsen BR, Poole AR. Chondrocalcin is identical with the C-propeptide of type II procollagen. Biochem J. 1986 Aug 01; 237(3):923-5. PMID: 3800925; PMCID: PMC1147077.
  375. Hayashi M, Ninomiya Y, Parsons J, Hayashi K, Olsen BR, Trelstad RL. Differential localization of mRNAs of collagen types I and II in chick fibroblasts, chondrocytes, and corneal cells by in situ hybridization using cDNA probes. J Cell Biol. 1986 Jun; 102(6):2302-9. PMID: 3011812; PMCID: PMC2114245.
  376. Konomi H, Seyer JM, Ninomiya Y, Olsen BR. Peptide-specific antibodies identify the alpha 2 chain as the proteoglycan subunit of type IX collagen. J Biol Chem. 1986 May 25; 261(15):6742-6. PMID: 2422170.
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  377. Ninomiya Y, Gordon M, van der Rest M, Schmid T, Linsenmayer T, Olsen BR. The developmentally regulated type X collagen gene contains a long open reading frame without introns. J Biol Chem. 1986 Apr 15; 261(11):5041-50. PMID: 3082876.
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  378. Lozano G, Ninomiya Y, Olsen BR. The structure of short-chain collagen genes. Prog Clin Biol Res. 1986; 217B:397-400. PMID: 3755828.
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  379. Konomi H, Ninomiya Y, Olsen BR. Tissue-specific expression of short-chain collagens. Prog Clin Biol Res. 1986; 217B:169-72. PMID: 3755827.
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  380. Ninomiya Y, van der Rest M, Mayne R, Lozano G, Olsen BR. Construction and characterization of cDNA encoding the alpha 2 chain of chicken type IX collagen. Biochemistry. 1985 Jul 16; 24(15):4223-9. PMID: 2996593.
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  381. Lozano G, Ninomiya Y, Thompson H, Olsen BR. A distinct class of vertebrate collagen genes encodes chicken type IX collagen polypeptides. Proc Natl Acad Sci U S A. 1985 Jun; 82(12):4050-4. PMID: 3858862; PMCID: PMC397932.
  382. van der Rest M, Mayne R, Ninomiya Y, Seidah NG, Chretien M, Olsen BR. The structure of type IX collagen. J Biol Chem. 1985 Jan 10; 260(1):220-5. PMID: 2981204.
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  383. Fleischmajer R, Olsen BR, Kuhn K (eds.). . Biology, Chemistry and Pathology of Collagen. 1985.
  384. Olsen BR, Ninomiya Y, Lozano G, Konomi H, Gordon M, Green G, Parsons J, Seyer J, Thompson H, Vasios G. Short-chain collagen genes and their expression in cartilage. Ann N Y Acad Sci. 1985; 460:141-53. PMID: 3868942.
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  385. Olsen BR, Ninomiya Y, Konomi H, Lozano G, Vasios G, Seyer J, Eikenberry J. . A novel class of collagen genes in vertebrates: Type IX collagen. Basement Membranes, (Shibata S, ed). 1985; 119-130.
  386. Mayne R, van der Rest M, Ninomiya Y, Olsen BR. The structure of type IX collagen. Ann N Y Acad Sci. 1985; 460:38-46. PMID: 3868958.
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  387. Ninomiya Y, Olsen BR. Synthesis and characterization of cDNA encoding a cartilage-specific short collagen. Proc Natl Acad Sci U S A. 1984 May; 81(10):3014-8. PMID: 6328487; PMCID: PMC345211.
  388. Ninomiya Y, Showalter AM, Olsen BR. . Collagen genes and cartilage differentiation. The Role of Extracellular Matrix in Development (Trelstad R, ed). 1984; 255-275.
  389. Fleischmajer R, Olsen BR, Timpl R, Perlish JS, Lovelace O. Collagen fibril formation during embryogenesis. Proc Natl Acad Sci U S A. 1983 Jun; 80(11):3354-8. PMID: 6574488; PMCID: PMC394041.
  390. Ninomiya Y, Showalter AM, Olsen BR. . Synthesis and characterization of chicken cartilage collagen cDNA. Proceedings of the Third International Conference on Limb Development and Regeneration, Part B, (Kelly RO, Goetinck PF, MacCabe JA, eds). 1983; 183-192.
  391. Olsen BR. . The carboxyl propeptides of procollagens: structural and functional considerations. (Kuehn K, Schoene H, Timpl R, eds). 1982; 225-236.
  392. Pesciotta DM, Olsen BR. . Cell biology of collagen secretion. Immunochemistry of the Extracellular Matrix, II, (Furthmayr H, ed). 1982; 1-18.
  393. Olsen BR, Dickson L. . The biosynthesis and processing of procollagens. The Chemistry and Biology of Mineralized Connective Tissues, (Veis A, ed). 1982; (Development in Biochemistry V:143-153.
  394. Pesciotta DM, Curran SF, Olsen BR. . Preparation of antisera specific for the amino acid carboxyl propeptides of type I and type II procollagens. Immunochemistry of the Extracellular Matrix, I, (Furthmayr H, ed). 1982; 91-109.
  395. Ninomiya Y, Showalter AM, Olsen BR. Synthesis and characterization of chicken cartilage collagen cDNA. Prog Clin Biol Res. 1982; 110 Pt B:183-92. PMID: 7167571.
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  396. Dickson LA, Ninomiya Y, Bernard MP, Pesciotta DM, Parsons J, Green G, Eikenberry EF, de Crombrugghe B, Vogeli G, Pastan I, Fietzek PP, Olsen BR. The exon/intron structure of the 3'-region of the pro alpha 2(I) collagen gene. J Biol Chem. 1981 Aug 25; 256(16):8407-15. PMID: 6267043.
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  397. Graves PN, Olsen BR, Fietzek PP, Prockop DJ, Monson JM. Comparison of the NH2-Terminal sequences of chick Type I preprocollagen chains synthesized in an nRNA-dependent reticulocyte lysate. Eur J Biochem. 1981 Aug; 118(2):363-9. PMID: 6269854.
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  398. Pesciotta DM, Dickson LA, Showalter AM, Eikenberry EF, de Crombrugghe B, Fietzek PP, Olsen BR. Primary structure of the carbohydrate-containing regions of the carboxyl propeptides of type I procollagen. FEBS Lett. 1981 Mar 23; 125(2):170-4. PMID: 7227547.
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  399. Olsen BR. . Collagen Biosynthesis. Cell Biology of Extracellular Matrix, (Hay ED, ed). 1981; 139-177.
  400. Cassidy K, Eikenberry EF, Olsen B, Brodsky B. X-ray diffraction investigations of collagen fibril structure in dermatosparactic lamb tissues. Lab Invest. 1980 Dec; 43(6):542-6. PMID: 7442130.
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  401. Pesciotta DM, Silkowitz MH, Fietzek PP, Graves PN, Berg RA, Olsen BR. Purification and characterization of the amino-terminal propeptide of Pro alpha 1(I) chains from embryonic chick tendon procollagen. Biochemistry. 1980 May 27; 19(11):2447-54. PMID: 6104509.
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  402. Yamamoto T, Sobel ME, Adams SL, Avvedimento VE, DiLauro R, Pastan I, de Crombrugghe B, Showalter A, Pesciotta D, Fietzek P, Olsen B. Construction of a recombinant bacterial plasmid containing pro-alpha 1(I) collagen DNA sequences. J Biol Chem. 1980 Mar 25; 255(6):2612-5. PMID: 6244285.
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  403. Showalter AM, Pesciotta DM, Eikenberry EF, Yamamoto T, Pastan I, DeCrombrugghe B, Fietzek PP, Olsen BR. Nucleotide sequence of a collagen cDNA-fragment coding for the carboxyl end of pro alpha 1(I)-chains. FEBS Lett. 1980 Feb 25; 111(1):61-5. PMID: 6987088.
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  404. Olsen BR. Inherited disorders of collagen metabolism. Biology of Collagen, (Viidik A, ed). 1980; 153-173.
  405. Olsen BR, Berg RA. Post-translational processing and secretion of procollagen in fibroblasts. Symp Soc Exp Biol. 1979; 33:57-78. PMID: 524274.
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  406. Olsen BR, Berg RA. . Post-translational processing and secretion of procollagen in fibroblasts. Secretory Mechanisms (B.S.E.B. Symposia), (Hopkins CR, Duncan CJ, eds.),. 1979; 57-78.
  407. Handley DA, Olsen BR. Butvar B-98 as a thin support film. Ultramicroscopy. 1979; 4(4):479-80. PMID: 531984.
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  408. Wick G, Olsen BR, Timpl R. Immunohistologic analysis of fetal and dermatosparactic calf and sheep skin with antisera to procollagen and collagen type I. Lab Invest. 1978 Aug; 39(2):151-6. PMID: 682599.
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  409. Gay S, Gay R, Olsen BR. . Immunoelectron microscopy. Electron Microscopy in Human Medicine, (Johannessen JV, ed). 1978; 243-258.
  410. Olsen BR, Schwartz M. . Secretion of macromolecules. Life Sciences Report II, (Silverstein SC, ed.). 1978; 391-410.
  411. Olsen BR, Guzman NA, Engel J, Condit C, Aase S. Purification and characterization of a peptide from the carboxy-terminal region of chick tendon procollagen type I. Biochemistry. 1977 Jun 28; 16(13):3030-6. PMID: 880293.
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  412. Hoffmann HP, Olsen BR, Chen HT, Prockop DJ. Segment-long-spacing aggregates and isolation of COOH-terminal peptides from type I procollagen. Proc Natl Acad Sci U S A. 1976 Dec; 73(12):4304-8. PMID: 1069985; PMCID: PMC431440.
  413. Holmquist J, Imasoto Y, Bengtsson E, Olsen B, Stenkvist B. A microspectrophotometric study of Papanicolaou-stained cervical cells as an aid in computerized image processing. J Histochem Cytochem. 1976 Dec; 24(12):1218-24. PMID: 63509.
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  414. Nowack H, Olsen BR, Timpl R. Characterization of the amino-terminal segment in type III procollagen. Eur J Biochem. 1976 Nov 01; 70(1):205-16. PMID: 188641.
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  415. Olsen BR, Hoffmann H, Prockop DJ. Interchain disulfide bonds at the COOH-terminal end of procollagen synthesized by matrix-free cells from chick embryonic tendon and cartilage. Arch Biochem Biophys. 1976 Jul; 175(1):341-50. PMID: 182083.
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  416. Normann T, Johannessen JV, Gautvik KM, Olsen BR, Brennhovd IO. Medullary carcinoma of the thyroid. Diagnostic problems. Cancer. 1976 Jul; 38(1):366-77. PMID: 947528.
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  417. Dahl HA, Olsen BR, Rinvik E. . Menneskets anatomi [Anatomy textbook]. 1976.
  418. Aase S, Roland M, Olsen BR. Ultrastructure of parietal cells before and after proximal gastric vagotomy in duodenal ulcer patients. Scand J Gastroenterol. 1976; 11(1):55-64. PMID: 1251133.
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  419. Nist C, Von Der Mark K, Hay ED, Olsen BR, Bornstein P, Ross R, Dehm P. Location of procollagen in chick corneal and tendon fibroblasts with ferritin-conjugated antibodies. J Cell Biol. 1975 Apr; 65(1):75-87. PMID: 1168646; PMCID: PMC2111168.
  420. Olsen BR, Berg RA, Kishida Y, Prockop DJ. Further characterization of embryonic tendon fibroblasts and the use of immunoferritin techniques to study collagen biosynthesis. J Cell Biol. 1975 Feb; 64(2):340-55. PMID: 163830; PMCID: PMC2109500.
  421. Kishida Y, Olsen BR, Berg RA, Prockop DJ. Two improved methods for preparing ferritin-protein conjugates for electron microscopy. J Cell Biol. 1975 Feb; 64(2):331-9. PMID: 803973; PMCID: PMC2109494.
  422. Olsen BR, Lie SO. [Nobel prize in medicine 1974 (Albert Claude, George Palade, Christian de Duve)]. Tidsskr Nor Laegeforen. 1974 Dec 10; 94(34-36):2400-3. PMID: 4614493.
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  423. Avigad G, Englard S, Olsen BR, Wolfenstein-Todel C, Wiggins R. Molecular properties of cis,cis-muconate cycloisomerase from Pseudomonas putida. J Mol Biol. 1974 Nov 15; 89(4):651-62. PMID: 4449126.
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  424. Dehm P, Olsen BR, Prockop DJ. Antibodies to chick-tendon procollagen. Affinity purification with the isolated disulfide-linded NH2-terminal extensions and reactivity with a component in embryonic serum. Eur J Biochem. 1974 Jul 01; 46(1):107-16. PMID: 4136533.
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  425. Olsen BR, Prockop DJ. Ferritin-conjugated antibodies used for labeling of organelles involved in the cellular synthesis and transport of procollagen. Proc Natl Acad Sci U S A. 1974 May; 71(5):2033-7. PMID: 4525314; PMCID: PMC388380.
  426. Olsen BR, Berg RA, Kishida Y, Prockop DJ. Collagen synthesis: localization of prolyl hydroxylase in tendon cells detected with ferritin-labeled antibodies. Science. 1973 Nov 23; 182(4114):825-7. PMID: 4355681.
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  427. Olsen BR, Alper R, Kefalides NA. Structural characterization of a soluble fraction from lens-capsule basement membrane. Eur J Biochem. 1973 Oct 05; 38(2):220-8. PMID: 4129819.
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  428. Olsen BR, Berg RA, Kivirikko KT, Prockop DJ. Structure of protocollagen proline hydroxylase from chick embryos. Eur J Biochem. 1973 May; 35(1):135-47. PMID: 4351527.
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  429. Olsen BR, Torgner IA, Christensen TB, Kvamme E. Ultrastructure of pig renal glutaminase. Evidence for conformational changes during polymer formation. J Mol Biol. 1973 Feb 25; 74(2):239-51. PMID: 4689954.
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  430. Jimenez SA, Dehm P, Olsen BR, Prokop DJ. Intracellular collagen and protocollagen from embryonic tendon cells. J Biol Chem. 1973 Jan 25; 248(2):720-9. PMID: 4684698.
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  431. Olsen BR. . Anatomi--Fra spekulasjon til moderne celleforskning. Familieboka. 1973; 97-99.
  432. Prockop DJ, Dehm P, Olsen BR, Berg RA, Grant ME, Uitto J, Kivirikko KI. . Recent studies on the biosynthesis of collagen. Biology of the Fibroblasts. 1973; 311-320.
  433. Berg RA, Olsen BR, Prockop DJ. Labeled antibodies to protocollagen proline hydroxylase from chick embryos for intracellular localization of the enzyme. Biochim Biophys Acta. 1972 Nov 28; 285(1):167-75. PMID: 4120059.
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  434. Dehm P, Jimenez SA, Olsen BR, Prockop DJ. A transport form of collagen from embryonic tendon: electron microscopic demonstration of an NH 2 -terminal extension and evidence suggesting the presence of cystine in the molecule (chick embryo-tropocollagen-gel filtration). Proc Natl Acad Sci U S A. 1972 Jan; 69(1):60-4. PMID: 4333046; PMCID: PMC427544.
  435. Prockop DJ, Dehm P, Olsen BR, Berg RA, Jimenze SA, and Kivirikko KI. . Collagen Synthesis: Relationship between "post mRNA" reactions and secretion of the molecule. Inflammation: Mechanisms and Control. 1972; 43-54.
  436. Huseby NE, Christensen TB, Olsen BR, Stormer FC. The pH 6 acetolactate-forming enzyme from Aerobacter aerogenes. Subunit structure. Eur J Biochem. 1971 May 28; 20(2):209-14. PMID: 5560406.
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  437. Hetland O, Olsen BR, Christensen TB, Stormer FC. Diacetyl (acetoin) reductase from Aerobacter aerogenes. Structural properties. Eur J Biochem. 1971 May 28; 20(2):200-5. PMID: 5560405.
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  438. Olsen BR, Berg RA, Sakakibara S, Kishida Y, Prockop DJ. The synthetic polytripeptides (Pro-Pro-Gly)10 and (Pro-Pro-Gly)20 form micro-crystalline structures similar to segmental structures formed by collagen. J Mol Biol. 1971 May 14; 57(3):589-95. PMID: 4103752.
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  439. Vegge T, Winther FO, Olsen BR. Horseradish peroxidase in plasma studied by gel filtration. Histochemie. 1971; 28(1):16-22. PMID: 5002924.
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  440. Berg RA, Olsen BR, Prockop DJ. Titration and melting curves of the collagen-like triple helices formed from (Pro-Pro-Gly) in aqueous solution. J Biol Chem. 1970 Nov 10; 245(21):5759-63. PMID: 5472371.
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  441. Olsen BR, Svenneby G, Kvamme E, Tveit B, Eskeland T. Formation and ultrastructure of enzymically active polymers of pig renal glutaminase. J Mol Biol. 1970 Sep 14; 52(2):239-45. PMID: 5530398.
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  442. Olsen BR, Jimenez SA, Kivirikko KI, Prockop DJ. Electron microscopy of protocollagen proline hydroxylase from chick embryos. J Biol Chem. 1970 May 25; 245(10):2649-55. PMID: 4193503.
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  443. Laszlo F, Olsen BR. Cyanogen bromide peptides from the alpha 1-chain of cod skin collagen. Eur J Biochem. 1969 Nov; 11(1):140-7. PMID: 5353597.
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  444. Fröholm LO, Olsen BR. A conformational model of serine transfer RNA proposed on the basis of electron microscopy. FEBS Lett. 1969 May; 3(3):182-184. PMID: 11947001.
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  445. Froholm LO, Olsen BR. Electron microscopy of transfer RNA. J Mol Biol. 1969 Mar 14; 40(2):305-6. PMID: 4903817.
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  446. Olsen BR. Electron microscope studies on collagen. V. The structure of segment-long-spacing aggregates consisting of molecules renaturated from the isolated alpha-3-fraction of rat tail tendon collagen. J Ultrastruct Res. 1967 Aug 30; 19(5):432-45. PMID: 6055778.
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  447. Olsen BR. Electron microscope studies on collagen. VI. The structure of segment-long-spacing aggregates consisting of molecules renatured from isolated alpha-fractions of codfish skin collagen. J Ultrastruct Res. 1967 Aug 30; 19(5):446-73. PMID: 6055779.
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  448. Olsen BR. . Ultrastructure of tropocollagen macromolecules and ordered collagen aggregates. 1967.
  449. Dahl HA, Jansen J, Olsen BR. . Menneskets anatomi og fysiology [Anatomy and physiology textbook]. 1966.
  450. Olsen BR. Electron microscope studies on collagen. IV. Structure of vitrosin fibrils and interaction properties of vitrosin molecules. J Ultrastruct Res. 1965 Aug; 13(1):172-91. PMID: 5891447.
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  451. OLSEN BR. ELECTRON MICROSCOPE STUDIES ON COLLAGEN. III. TRYPTIC DIGESTION OF TROPOCOLLAGEN MACROMOLECULES. Z Zellforsch Mikrosk Anat. 1964 Jan 31; 61:913-9. PMID: 14137342.
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  452. VAN PILSUM JF, OLSEN B, TAYLOR D, ROZYCKI T, PIERCE JC. Transamidinase activities, in vitro, of tissues from various mammals and from rats fed protein-free, creatine-supplemented and normal diets. Arch Biochem Biophys. 1963 Mar; 100:520-4. PMID: 13996106.
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  453. OLSEN BR. Electron microscope studies on collagen. I. Native collagen fibrils. Z Zellforsch Mikrosk Anat. 1963; 59:184-98. PMID: 13940064.
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  454. OLSEN BR. Electron microscope studies on collagen. II. Mechanism of linear polymerization of tropocollagen molecules. Z Zellforsch Mikrosk Anat. 1963; 59:199-213. PMID: 13940065.
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