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Jane Ann Driver, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. I01CX000934 (DRIVER, JANE A) Jul 1, 2014 - Jun 30, 2018
    Investigating the link between cancer and neurodegenerative disease
    Role: Principal Investigator
  2. T35AG038027 (DRIVER, JANE A) Aug 1, 2010 - Jul 31, 2020
    Greater Boston Medical Student Training in Aging Research
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Relyea MR, Portnoy GA, Klap R, Yano EM, Fodor A, Keith JA, Driver JA, Brandt CA, Haskell SG, Adams L. Evaluating Bystander Intervention Training to Address Patient Harassment at the Veterans Health Administration. Womens Health Issues. 2020 Aug 20. PMID: 32830008.
  2. Orkaby AR, Driver JA, Ho YL, Lu B, Costa L, Honerlaw J, Galloway A, Vassy JL, Forman DE, Gaziano JM, Gagnon DR, Wilson PWF, Cho K, Djousse L. Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older. JAMA. 2020 07 07; 324(1):68-78. PMID: 32633800.
  3. Jacob ME, Ni P, Driver J, Leritz E, Leveille SG, Jette AM, Bean JF. Burden and Patterns of Multimorbidity: Impact on Disablement in Older Adults. Am J Phys Med Rehabil. 2020 05; 99(5):359-365. PMID: 32301768.
  4. DuMontier C, Loh KP, Bain PA, Silliman RA, Hshieh T, Abel GA, Djulbegovic B, Driver JA, Dale W. Defining Undertreatment and Overtreatment in Older Adults With Cancer: A Scoping Literature Review. J Clin Oncol. 2020 Aug 01; 38(22):2558-2569. PMID: 32250717.
  5. Jacob ME, Ni P, Driver J, Leritz E, Leveille SG, Jette AM, Bean JF. Burden and Patterns of Multi-morbidity: Impact on Disablement in Older Adults. Am J Phys Med Rehabil. 2020 Jan 16. PMID: 31972615.
  6. Ward RE, Orkaby AR, Chen J, Hshieh TT, Driver JA, Gaziano JM, Djousse L. Association between Diet Quality and Frailty Prevalence in the Physicians' Health Study. J Am Geriatr Soc. 2020 Apr; 68(4):770-776. PMID: 31840808.
  7. Imran TF, Orkaby A, Chen J, Selvaraj S, Driver JA, Gaziano JM, Djoussé L. Walking pace is inversely associated with risk of death and cardiovascular disease: The Physicians' Health Study. Atherosclerosis. 2019 10; 289:51-56. PMID: 31450014.
  8. Orkaby AR, Nussbaum L, Ho YL, Gagnon D, Quach L, Ward R, Quaden R, Yaksic E, Harrington K, Paik JM, Kim DH, Wilson PW, Gaziano JM, Djousse L, Cho K, Driver JA. The Burden of Frailty Among U.S. Veterans and Its Association With Mortality, 2002-2012. J Gerontol A Biol Sci Med Sci. 2019 07 12; 74(8):1257-1264. PMID: 30307533.
    Citations:    Fields:    
  9. Sager ZS, Buss MK, Hill KP, Driver JA, Skarf LM. Managing Opioid Use Disorder in the Setting of a Terminal Disease: Opportunities and Challenges. J Palliat Med. 2020 02; 23(2):296-299. PMID: 31295046.
  10. Gupta A, Preis SR, Beiser AS, Splansky GL, DeCarli CS, Au R, Driver JA. Relationship of Cancer to Brain Aging Markers of Alzheimer's Disease: The Framingham Heart Study. Adv Geriatr Med Res. 2019; 1. PMID: 31355371.
  11. Chen MY, Orkaby AR, Rosenberg MA, Driver JA. Frailty, Implantable Cardioverter Defibrillators, and Mortality: a Systematic Review. J Gen Intern Med. 2019 10; 34(10):2224-2231. PMID: 31264082.
  12. Regier NG, Naik AD, Mulligan EA, Nasreddine ZS, Driver JA, Sada YH, Moye J. Cancer-related cognitive impairment and associated factors in a sample of older male oral-digestive cancer survivors. Psychooncology. 2019 07; 28(7):1551-1558. PMID: 31134710.
  13. Liu MA, DuMontier C, Murillo A, Hshieh TT, Bean JF, Soiffer RJ, Stone RM, Abel GA, Driver JA. Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies. Blood. 2019 07 25; 134(4):374-382. PMID: 31167800.
  14. Catalá-López F, Forés-Martos J, Driver JA, Page MJ, Hutton B, Ridao M, Alonso-Arroyo A, Macías Saint-Gerons D, Gènova-Maleras R, Valderas JM, Vieta E, Valencia A, Tabarés-Seisdedos R. Association of Anorexia Nervosa With Risk of Cancer: A Systematic Review and Meta-analysis. JAMA Netw Open. 2019 06 05; 2(6):e195313. PMID: 31173122.
  15. Reese RL, Clement SA, Syeda S, Hawley CE, Gosian JS, Cai S, Jensen LL, Kind AJH, Driver JA. Coordinated-Transitional Care for Veterans with Heart Failure and Chronic Lung Disease. J Am Geriatr Soc. 2019 07; 67(7):1502-1507. PMID: 31081946.
  16. DuMontier C, Liu MA, Murillo A, Hshieh T, Javedan H, Soiffer R, Stone RM, Driver JA, Abel GA. Function, Survival, and Care Utilization Among Older Adults With Hematologic Malignancies. J Am Geriatr Soc. 2019 05; 67(5):889-897. PMID: 30945759.
  17. Zhu Z, Lin Y, Li X, Driver JA, Liang L. Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis. Hum Genet. 2019 Mar; 138(3):271-285. PMID: 30805717.
  18. Orkaby AR, Lunetta KL, Sun FJ, Driver JA, Benjamin EJ, Hamburg NM, Mitchell GF, Vasan RS, Murabito JM. Cross-Sectional Association of Frailty and Arterial Stiffness in Community-Dwelling Older Adults: The Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):373-379. PMID: 29917058.
    Citations: 1     Fields:    
  19. Bean JF, Orkaby AR, Driver JA. Geriatric Rehabilitation Should Not Be an Oxymoron: A Path Forward. Arch Phys Med Rehabil. 2019 05; 100(5):995-1000. PMID: 30735624.
  20. Hshieh TT, Driver JA, Abel GA. Cognitive Impairment Among Older Patients With Hematologic Cancers-Reply. JAMA Oncol. 2018 12 01; 4(12):1784. PMID: 30286229.
  21. Murillo A, Cronin AM, Laubach JP, Hshieh TT, Tanasijevic AM, Richardson PG, Driver JA, Abel GA. Performance of the International Myeloma Working Group myeloma frailty score among patients 75 and older. J Geriatr Oncol. 2019 05; 10(3):486-489. PMID: 30472368.
    Citations:    Fields:    
  22. Liu MA, Nguyen J, Driver JA. Influence of age and marital status on stage at diagnosis and survival of patients with Merkel cell carcinoma: A Surveillance, Epidemiology, and End Results registry-based cohort study. J Am Acad Dermatol. 2018 Dec; 79(6):1146-1148. PMID: 29864470.
    Citations:    Fields:    Translation:Humans
  23. Hshieh TT, Jung WF, Grande LJ, Chen J, Stone RM, Soiffer RJ, Driver JA, Abel GA. Prevalence of Cognitive Impairment and Association With Survival Among Older Patients With Hematologic Cancers. JAMA Oncol. 2018 05 01; 4(5):686-693. PMID: 29494732.
    Citations: 1     Fields:    
  24. Houck AL, Seddighi S, Driver JA. At the Crossroads Between Neurodegeneration and Cancer: A Review of Overlapping Biology and Its Implications. Curr Aging Sci. 2018; 11(2):77-89. PMID: 29552989.
    Citations:    Fields:    
  25. Orkaby AR, Onuma O, Qazi S, Gaziano JM, Driver JA. Preventing cardiovascular disease in older adults: One size does not fit all. Cleve Clin J Med. 2018 Jan; 85(1):55-64. PMID: 29328899.
    Citations:    Fields:    Translation:Humans
  26. Albayram O, Kondo A, Mannix R, Smith C, Tsai CY, Li C, Herbert MK, Qiu J, Monuteaux M, Driver J, Yan S, Gormley W, Puccio AM, Okonkwo DO, Lucke-Wold B, Bailes J, Meehan W, Zeidel M, Lu KP, Zhou XZ. Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae. Nat Commun. 2017 10 17; 8(1):1000. PMID: 29042562.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  27. Orkaby AR, Cho K, Cormack J, Gagnon DR, Driver JA. Metformin vs sulfonylurea use and risk of dementia in US veterans aged =65 years with diabetes. Neurology. 2017 Oct 31; 89(18):1877-1885. PMID: 28954880.
    Citations: 2     Fields:    Translation:Humans
  28. Catalá-López F, Hutton B, Page MJ, Ridao M, Driver JA, Alonso-Arroyo A, Forés-Martos J, Macías Saint-Gerons D, Vieta E, Valencia A, Tabarés-Seisdedos R. Risk of mortality among children, adolescents, and adults with autism spectrum disorder or attention deficit hyperactivity disorder and their first-degree relatives: a protocol for a systematic review and meta-analysis of observational studies. Syst Rev. 2017 09 15; 6(1):189. PMID: 28915839.
    Citations:    Fields:    Translation:Humans
  29. Orkaby AR, Gaziano JM, Djousse L, Driver JA. Statins for Primary Prevention of Cardiovascular Events and Mortality in Older Men. J Am Geriatr Soc. 2017 Nov; 65(11):2362-2368. PMID: 28892121.
    Citations: 1     Fields:    Translation:Humans
  30. Feng YA, Cho K, Lindstrom S, Kraft P, Cormack J, Liang L, Driver JA. Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics. Hum Genet. 2017 10; 136(10):1341-1351. PMID: 28780673.
    Citations: 1     Fields:    Translation:Humans
  31. Frain L, Swanson D, Cho K, Gagnon D, Lu KP, Betensky RA, Driver J. Association of cancer and Alzheimer's disease risk in a national cohort of veterans. Alzheimers Dement. 2017 Dec; 13(12):1364-1370. PMID: 28711346.
    Citations: 4     Fields:    Translation:Humans
  32. Catalá-López F, Hutton B, Driver JA, Ridao M, Valderas JM, Gènova-Maleras R, Forés-Martos J, Alonso-Arroyo A, Saint-Gerons DM, Vieta E, Valencia A, Tabarés-Seisdedos R. Anorexia nervosa and cancer: a protocol for a systematic review and meta-analysis of observational studies. Syst Rev. 2017 07 11; 6(1):137. PMID: 28693568.
    Citations: 1     Fields:    Translation:Humans
  33. Catalá-López F, Hutton B, Driver JA, Page MJ, Ridao M, Valderas JM, Alonso-Arroyo A, Forés-Martos J, Martínez S, Gènova-Maleras R, Macías-Saint-Gerons D, Crespo-Facorro B, Vieta E, Valencia A, Tabarés-Seisdedos R. Cancer and central nervous system disorders: protocol for an umbrella review of systematic reviews and updated meta-analyses of observational studies. Syst Rev. 2017 04 04; 6(1):69. PMID: 28376926.
    Citations: 4     Fields:    Translation:Humans
  34. Driver JA, Viswanathan AN. Frailty measure is more predictive of outcomes after curative therapy for endometrial cancer than traditional risk factors in women 60 and older. Gynecol Oncol. 2017 06; 145(3):526-530. PMID: 28359689.
    Citations:    Fields:    Translation:Humans
  35. Orkaby AR, Hshieh TT, Gaziano JM, Djousse L, Driver JA. Comparison of two frailty indices in the physicians' health study. Arch Gerontol Geriatr. 2017 Jul; 71:21-27. PMID: 28242579.
    Citations: 1     Fields:    Translation:Humans
  36. Snyder HM, Ahles T, Calderwood S, Carrillo MC, Chen H, Chang CH, Craft S, De Jager P, Driver JA, Fillit H, Knopman D, Lotze M, Tierney MC, Petanceska S, Saykin A, Seshadri S, Shineman D, Ganguli M. Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. Alzheimers Dement. 2017 Mar; 13(3):267-273. PMID: 27998721.
    Citations: 1     Fields:    Translation:Humans
  37. Jackson CE, Grande LJ, Doherty K, Archambault E, Kelly B, Driver JA, Milberg WP, McGlinchey R, Rudolph JL. The Clock-in-the-Box, a brief cognitive screen, is associated with failure to return home in an elderly hospitalized sample. Clin Interv Aging. 2016; 11:1715-1721. PMID: 27920510.
    Citations:    Fields:    Translation:HumansPHPublic Health
  38. Rebello KE, Gosian J, Salow M, Sweeney P, Rudolph JL, Driver JA. The Rural PILL Program: A Postdischarge Telepharmacy Intervention for Rural Veterans. J Rural Health. 2017 06; 33(3):332-339. PMID: 27606938.
    Citations:    Fields:    Translation:Humans
  39. Liu MA, Hshieh T, Condron N, Wadleigh M, Abel GA, Driver JA. Relationship between physician and patient assessment of performance status and survival in a large cohort of patients with haematologic malignancies. Br J Cancer. 2016 09 27; 115(7):858-61. PMID: 27552440.
    Citations: 1     Fields:    Translation:Humans
  40. Rudolph JL, Doherty K, Kelly B, Driver JA, Archambault E. Validation of a Delirium Risk Assessment Using Electronic Medical Record Information. J Am Med Dir Assoc. 2016 Mar 01; 17(3):244-8. PMID: 26705000.
    Citations: 1     Fields:    Translation:Humans
  41. Kondo A, Shahpasand K, Mannix R, Qiu J, Moncaster J, Chen CH, Yao Y, Lin YM, Driver JA, Sun Y, Wei S, Luo ML, Albayram O, Huang P, Rotenberg A, Ryo A, Goldstein LE, Pascual-Leone A, McKee AC, Meehan W, Zhou XZ, Lu KP. Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy. Nature. 2015 Jul 23; 523(7561):431-436. PMID: 26176913.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  42. Fega KR, Abel GA, Motyckova G, Sherman AE, DeAngelo DJ, Steensma DP, Galinsky I, Wadleigh M, Stone RM, Driver JA. Non-hematologic predictors of mortality improve the prognostic value of the international prognostic scoring system for MDS in older adults. J Geriatr Oncol. 2015 Jul; 6(4):288-98. PMID: 26073533.
    Citations: 4     Fields:    Translation:Humans
  43. Driver JA, Zhou XZ, Lu KP. Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease. Biochim Biophys Acta. 2015 Oct; 1850(10):2069-76. PMID: 25583562.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  44. Demetrius LA, Driver JA. Preventing Alzheimer's disease by means of natural selection. J R Soc Interface. 2015 Jan 06; 12(102):20140919. PMID: 25551134.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  45. Driver JA. Inverse association between cancer and neurodegenerative disease: review of the epidemiologic and biological evidence. Biogerontology. 2014 Dec; 15(6):547-57. PMID: 25113739.
    Citations: 24     Fields:    Translation:Humans
  46. Cho K, Gagnon DR, Driver JA, Altincatal A, Kosik N, Lanes S, Lawler EV. Dementia Coding, Workup, and Treatment in the VA New England Healthcare System. Int J Alzheimers Dis. 2014; 2014:821894. PMID: 24701364.
    Citations: 1     
  47. Driver JA, Zhou XZ, Lu KP. Regulation of protein conformation by Pin1 offers novel disease mechanisms and therapeutic approaches in Alzheimer's disease. Discov Med. 2014 Feb; 17(92):93-9. PMID: 24534472.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  48. Demetrius LA, Driver J. Alzheimer's as a metabolic disease. Biogerontology. 2013 Dec; 14(6):641-9. PMID: 24249045.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  49. Sherman AE, Motyckova G, Fega KR, Deangelo DJ, Abel GA, Steensma D, Wadleigh M, Stone RM, Driver JA. Geriatric assessment in older patients with acute myeloid leukemia: a retrospective study of associated treatment and outcomes. Leuk Res. 2013 Sep; 37(9):998-1003. PMID: 23747082.
    Citations: 18     Fields:    Translation:Humans
  50. Butler D, Kowall NW, Lawler E, Michael Gaziano J, Driver JA. Underuse of diagnostic codes for specific dementias in the Veterans Affairs New England healthcare system. J Am Geriatr Soc. 2012 May; 60(5):910-5. PMID: 22587853.
    Citations: 10     Fields:    Translation:Humans
  51. Driver JA, Beiser A, Au R, Kreger BE, Splansky GL, Kurth T, Kiel DP, Lu KP, Seshadri S, Wolf PA. Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study. BMJ. 2012 Mar 12; 344:e1442. PMID: 22411920.
    Citations: 79     Fields:    Translation:Humans
  52. Djoussé L, Driver JA, Gaziano JM, Buring JE, Lee IM. Association between modifiable lifestyle factors and residual lifetime risk of diabetes. Nutr Metab Cardiovasc Dis. 2013 Jan; 23(1):17-22. PMID: 21982361.
    Citations: 11     Fields:    Translation:Humans
  53. Driver JA, Logroscino G, Lu L, Gaziano JM, Kurth T. Use of non-steroidal anti-inflammatory drugs and risk of Parkinson's disease: nested case-control study. BMJ. 2011 Jan 20; 342:d198. PMID: 21252104.
    Citations: 17     Fields:    Translation:Humans
  54. Driver JA, Lu KP. Pin1: a new genetic link between Alzheimer's disease, cancer and aging. Curr Aging Sci. 2010 Dec; 3(3):158-65. PMID: 20735350.
    Citations: 25     Fields:    Translation:HumansAnimals
  55. Driver JA, Yung R, Gaziano JM, Kurth T. Chronic disease in men with newly diagnosed cancer: a nested case-control study. Am J Epidemiol. 2010 Aug 01; 172(3):299-308. PMID: 20603278.
    Citations: 9     Fields:    Translation:Humans
  56. Ma SL, Tang NL, Tam CW, Lui VW, Lam LC, Chiu HF, Driver JA, Pastorino L, Lu KP. A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease. Neurobiol Aging. 2012 Apr; 33(4):804-13. PMID: 20580132.
    Citations: 15     Fields:    Translation:HumansCells
  57. Bajaj A, Driver JA, Schernhammer ES. Parkinson's disease and cancer risk: a systematic review and meta-analysis. Cancer Causes Control. 2010 May; 21(5):697-707. PMID: 20054708.
    Citations: 65     Fields:    Translation:Humans
  58. Djoussé L, Driver JA, Gaziano JM. Relation between modifiable lifestyle factors and lifetime risk of heart failure. JAMA. 2009 Jul 22; 302(4):394-400. PMID: 19622818.
    Citations: 87     Fields:    Translation:Humans
  59. Driver JA, Logroscino G, Gaziano JM, Kurth T. Incidence and remaining lifetime risk of Parkinson disease in advanced age. Neurology. 2009 Feb 03; 72(5):432-8. PMID: 19188574.
    Citations: 39     Fields:    Translation:Humans
  60. Driver JA, Djoussé L, Logroscino G, Gaziano JM, Kurth T. Incidence of cardiovascular disease and cancer in advanced age: prospective cohort study. BMJ. 2008 Dec 09; 337:a2467. PMID: 19066258.
    Citations: 30     Fields:    Translation:Humans
  61. Driver JA, Djousse L, Logroscino G, Gaziano JM, Kurth T. The Incidence of Cardiovascular Disease and Cancer in the Very Old: A Prospective Cohort Study. . BMJ. 2008; In press..
  62. Driver JA, Smith A, Buring JE, Gaziano JM, Kurth T, Logroscino G. Prospective cohort study of type 2 diabetes and the risk of Parkinson's disease. Diabetes Care. 2008 Oct; 31(10):2003-5. PMID: 18599528.
    Citations: 26     Fields:    Translation:Humans
  63. Driver JA, Kurth T, Buring JE, Gaziano JM, Logroscino G. Parkinson disease and risk of mortality: a prospective comorbidity-matched cohort study. Neurology. 2008 Apr 15; 70(16 Pt 2):1423-30. PMID: 18413567.
    Citations: 36     Fields:    Translation:Humans
  64. Driver JA, Kurth T, Buring JE, Gaziano JM, Logroscino G. Prospective case-control study of nonfatal cancer preceding the diagnosis of Parkinson's disease. Cancer Causes Control. 2007 Sep; 18(7):705-11. PMID: 17562193.
    Citations: 19     Fields:    Translation:Humans
  65. Driver JA, Logroscino G, Buring JE, Gaziano JM, Kurth T. A prospective cohort study of cancer incidence following the diagnosis of Parkinson's disease. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1260-5. PMID: 17548694.
    Citations: 37     Fields:    Translation:Humans
  66. Driver JA, Gaziano JM, Gelber RP, Lee IM, Buring JE, Kurth T. Development of a risk score for colorectal cancer in men. Am J Med. 2007 Mar; 120(3):257-63. PMID: 17349449.
    Citations: 31     Fields:    Translation:HumansPHPublic Health
  67. Driver JA, Cohen RI. . Management of pain in the elderly cancer patient. Clinical Geriatrics. 2003; 11(7):34-40.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.