Harvard Catalyst Profiles

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Clemens Scherzer, M.D.

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Available: 04/05/22, Expires: 06/01/23

How does the human genome program 86 billion highly specialized neurons in the human brain? How is this program disrupted by diseases of the brain? In the inter-disciplinary Neurogenomics Lab, genomicists and computational and clinical scientists use Big Data to search for the answers to these big questions. We use next-generation genomics technologies to identify the complete set of building blocks and instructions needed to make healthy human brain cells and to discover which are defective in Parkinson's, Huntington's, and Alzheimer's disease. In our translational work we use genome, epigenome, metabolome, and digital health IT to develop a future personalized medicine for patients with Parkinson's and other neurologic diseases designed to diagnose and treat the right patient, with the right medicine, at the right time.

completed student projects
Discovering Circular RNAs in Dopamine Neurons of Human Brain: Implications for Parkinson’s Disease
Summer, 06/15/15 - 08/07/15

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. U01NS120637 (DONG, XIANJUN) Sep 30, 2020 - Aug 31, 2021
    NIH
    AI2AMP-PD: Accelerating Parkinsons Diagnosis using Multi-omics and Artificial Intelligence
    Role: Co-Principal Investigator
  2. R01NS115144 (SCHERZER, CLEMENS R) Sep 20, 2019 - Aug 31, 2024
    NIH
    Genome-wide Prediction of Dementia in Parkinson Disease
    Role: Principal Investigator
  3. RF1AG057331 (FEANY, MEL B) Sep 15, 2017 - Mar 31, 2022
    NIH
    Integrative Multi-Omic Discovery of Proximal Mechanisms Driving Age-Dependent Neurodegeneration
    Role: Co-Principal Investigator
  4. U01NS100603 (SCHERZER, CLEMENS R) Sep 30, 2016 - Aug 31, 2021
    NIH
    GBA pathway markers for Lewy body dementias
    Role: Principal Investigator
  5. U01NS095736 (SCHERZER, CLEMENS R) Sep 30, 2016 - Aug 31, 2020
    NIH
    Parkinson Disease: Predicting the Future
    Role: Principal Investigator

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© 2023 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.