Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Leo E. Otterbein, Ph.D.

Co-Author

This page shows the publications co-authored by Leo Otterbein and Barbara Wegiel.
Connection Strength

7.926
  1. Heme as a danger molecule in pathogen recognition. Free Radic Biol Med. 2015 Dec; 89:651-61.
    View in: PubMed
    Score: 0.654
  2. Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation. J Clin Invest. 2014 Nov; 124(11):4926-40.
    View in: PubMed
    Score: 0.610
  3. Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells. Cell Death Dis. 2014 Mar 20; 5:e1139.
    View in: PubMed
    Score: 0.587
  4. Heme oxygenase-1: a metabolic nike. Antioxid Redox Signal. 2014 Apr 10; 20(11):1709-22.
    View in: PubMed
    Score: 0.585
  5. Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth. Cancer Res. 2013 Dec 01; 73(23):7009-21.
    View in: PubMed
    Score: 0.569
  6. The social network of carbon monoxide in medicine. Trends Mol Med. 2013 Jan; 19(1):3-11.
    View in: PubMed
    Score: 0.534
  7. Go green: the anti-inflammatory effects of biliverdin reductase. Front Pharmacol. 2012; 3:47.
    View in: PubMed
    Score: 0.511
  8. Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18849-54.
    View in: PubMed
    Score: 0.498
  9. Heme oxygenase-1 and carbon monoxide modulate DNA repair through ataxia-telangiectasia mutated (ATM) protein. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14491-6.
    View in: PubMed
    Score: 0.491
  10. Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury. Circulation. 2010 Feb 02; 121(4):537-48.
    View in: PubMed
    Score: 0.440
  11. Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt. J Biol Chem. 2009 Aug 07; 284(32):21369-78.
    View in: PubMed
    Score: 0.422
  12. Inhale to survive, cycle or die? Carbon monoxide and cellular proliferation. . 2008 May 15; 7(10):1379-84.
    View in: PubMed
    Score: 0.387
  13. Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. J Immunol. 2019 05 15; 202(10):2982-2990.
    View in: PubMed
    Score: 0.208
  14. Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth. Oncotarget. 2016 Apr 26; 7(17):23919-32.
    View in: PubMed
    Score: 0.170
  15. Heme oxygenase-1 in macrophages controls prostate cancer progression. Oncotarget. 2015 Oct 20; 6(32):33675-88.
    View in: PubMed
    Score: 0.164
  16. Carbon monoxide induces chromatin remodelling to facilitate endothelial cell migration. Thromb Haemost. 2014 May 05; 111(5):951-9.
    View in: PubMed
    Score: 0.145
  17. Intraoperative administration of inhaled carbon monoxide reduces delayed graft function in kidney allografts in Swine. Am J Transplant. 2010 Nov; 10(11):2421-30.
    View in: PubMed
    Score: 0.116
  18. Molecular pathways in the progression of hormone-independent and metastatic prostate cancer. Curr Cancer Drug Targets. 2010 Jun; 10(4):392-401.
    View in: PubMed
    Score: 0.113
  19. Cystatin C is downregulated in prostate cancer and modulates invasion of prostate cancer cells via MAPK/Erk and androgen receptor pathways. PLoS One. 2009 Nov 23; 4(11):e7953.
    View in: PubMed
    Score: 0.109
  20. Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis. J Natl Cancer Inst. 2008 Jul 16; 100(14):1022-36.
    View in: PubMed
    Score: 0.099
  21. Heme oxygenase and carbon monoxide initiate homeostatic signaling. J Mol Med (Berl). 2008 Mar; 86(3):267-79.
    View in: PubMed
    Score: 0.095
  22. Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages. J Immunol. 2007 May 01; 178(9):5921-9.
    View in: PubMed
    Score: 0.091
  23. Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5109-14.
    View in: PubMed
    Score: 0.090
  24. Carbon monoxide reverses established pulmonary hypertension. J Exp Med. 2006 Sep 04; 203(9):2109-19.
    View in: PubMed
    Score: 0.087
  25. Bilirubin suppresses Th17 immunity in colitis by upregulating CD39. JCI Insight. 2017 May 04; 2(9).
    View in: PubMed
    Score: 0.046
  26. Carbon monoxide inhibits sprouting angiogenesis and vascular endothelial growth factor receptor-2 phosphorylation. Thromb Haemost. 2015 Feb; 113(2):329-37.
    View in: PubMed
    Score: 0.038
  27. Biliverdin modulates the expression of C5aR in response to endotoxin in part via mTOR signaling. Biochem Biophys Res Commun. 2014 Jun 20; 449(1):94-9.
    View in: PubMed
    Score: 0.037
  28. Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules. J Biol Chem. 2012 Sep 14; 287(38):32113-23.
    View in: PubMed
    Score: 0.033
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.