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William G. Richards, PH.D.

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This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Follo C, Cheng Y, Richards WG, Bueno R, Broaddus VC. Autophagy facilitates the release of immunogenic signals following chemotherapy in 3D models of mesothelioma. Mol Carcinog. 2019 Jun 19. PMID: 31215708.
    Citations:    
  2. Zilionis R, Engblom C, Pfirschke C, Savova V, Zemmour D, Saatcioglu HD, Krishnan I, Maroni G, Meyerovitz CV, Kerwin CM, Choi S, Richards WG, De Rienzo A, Tenen DG, Bueno R, Levantini E, Pittet MJ, Klein AM. Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species. Immunity. 2019 May 21; 50(5):1317-1334.e10. PMID: 30979687.
    Citations:    
  3. Díaz-Tocados JM, Rodríguez-Ortiz ME, Almadén Y, Pineda C, Martínez-Moreno JM, Herencia C, Vergara N, Pendón-Ruiz de Mier MV, Santamaría R, Rodelo-Haad C, Casado-Díaz A, Lorenzo V, Carvalho C, Frazão JM, Felsenfeld AJ, Richards WG, Aguilera-Tejero E, Rodríguez M, López I, Muñoz-Castañeda JR. Calcimimetics maintain bone turnover in uremic rats despite the concomitant decrease in parathyroid hormone concentration. Kidney Int. 2019 May; 95(5):1064-1078. PMID: 30878213.
    Citations:    
  4. Follo C, Barbone D, Richards WG, Bueno R, Courtney Broaddus V. Autophagy in 3D In Vitro and Ex Vivo Cancer Models. Methods Mol Biol. 2019; 1880:491-510. PMID: 30610717.
    Citations:    Fields:    
  5. Yu H, Chen Z, Ballman KV, Watson MA, Govindan R, Lanc I, Beer DG, Bueno R, Chirieac LR, Chui MH, Chen G, Franklin WA, Gandara DR, Genova C, Brovsky KA, Joshi MM, Merrick DT, Richards WG, Rivard CJ, Harpole DH, Tsao MS, van Bokhoven A, Shepherd FA, Hirsch FR. Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. J Thorac Oncol. 2019 Jan; 14(1):25-36. PMID: 30253973.
    Citations:    Fields:    
  6. Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramirez-Moya J, Du P, Kim W, Tang S, Sliz P, Santisteban P, George RE, Richards WG, Wong KK, Locker N, Slack FJ, Gregory RI. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature. 2018 09; 561(7724):556-560. PMID: 30232453.
    Citations:    Fields:    
  7. Shi SY, Lu YW, Richardson J, Min X, Weiszmann J, Richards WG, Wang Z, Zhang Z, Zhang J, Li Y. A systematic dissection of sequence elements determining ß-Klotho and FGF interaction and signaling. Sci Rep. 2018 Jul 23; 8(1):11045. PMID: 30038432.
    Citations:    Fields:    
  8. Verkaik M, Juni RP, van Loon EPM, van Poelgeest EM, Kwekkeboom RFJ, Gam Z, Richards WG, Ter Wee PM, Hoenderop JG, Eringa EC, Vervloet MG. FGF23 impairs peripheral microvascular function in renal failure. Am J Physiol Heart Circ Physiol. 2018 Nov 01; 315(5):H1414-H1424. PMID: 30028196.
    Citations:    Fields:    
  9. Bell R, Lipham J, Louie B, Williams V, Luketich J, Hill M, Richards W, Dunst C, Lister D, McDowell-Jacobs L, Reardon P, Woods K, Gould J, Buckley FP, Kothari S, Khaitan L, Smith CD, Park A, Smith C, Jacobsen G, Abbas G, Katz P. Laparoscopic magnetic sphincter augmentation versus double-dose proton pump inhibitors for management of moderate-to-severe regurgitation in GERD: a randomized controlled trial. Gastrointest Endosc. 2019 01; 89(1):14-22.e1. PMID: 30031018.
    Citations:    
  10. Burt BM, Richards WG, Lee HS, Bartel S, Dasilva MC, Gill RR, Jaklitsch MT, Johnson BE, Swanson SJ, Bueno R, Sugarbaker DJ. A Phase I Trial of Surgical Resection and Intraoperative Hyperthermic Cisplatin and Gemcitabine for Pleural Mesothelioma. J Thorac Oncol. 2018 09; 13(9):1400-1409. PMID: 29753120.
    Citations:    Fields:    
  11. Gill RR, Yeap BY, Bueno R, Richards WG. Quantitative Clinical Staging for Patients With Malignant Pleural Mesothelioma. J Natl Cancer Inst. 2018 03 01; 110(3):258-264. PMID: 29931180.
    Citations:    Fields:    
  12. Shi SY, Lu YW, Liu Z, Stevens J, Murawsky CM, Wilson V, Hu Z, Richards WG, Michaels ML, Zhang J, Yan W, Li Y. A biparatopic agonistic antibody that mimics fibroblast growth factor 21 ligand activity. J Biol Chem. 2018 04 20; 293(16):5909-5919. PMID: 29483191.
    Citations:    Fields:    Translation:HumansAnimalsCells
  13. Follo C, Cheng Y, Richards WG, Bueno R, Broaddus VC. Inhibition of autophagy initiation potentiates chemosensitivity in mesothelioma. Mol Carcinog. 2018 03; 57(3):319-332. PMID: 29073722.
    Citations:    Fields:    Translation:HumansCells
  14. Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, Wei Z, Palakurthi S, Bittinger M, Vitzthum H, Kim JW, Merlino A, Quinn M, Venkataramani C, Kaplan JA, Portell A, Gokhale PC, Phillips B, Smart A, Rotem A, Jones RE, Keogh L, Anguiano M, Stapleton L, Jia Z, Barzily-Rokni M, Cañadas I, Thai TC, Hammond MR, Vlahos R, Wang ES, Zhang H, Li S, Hanna GJ, Huang W, Hoang MP, Piris A, Eliane JP, Stemmer-Rachamimov AO, Cameron L, Su MJ, Shah P, Izar B, Thakuria M, LeBoeuf NR, Rabinowits G, Gunda V, Parangi S, Cleary JM, Miller BC, Kitajima S, Thummalapalli R, Miao B, Barbie TU, Sivathanu V, Wong J, Richards WG, Bueno R, Yoon CH, Miret J, Herlyn M, Garraway LA, Van Allen EM, Freeman GJ, Kirschmeier PT, Lorch JH, Ott PA, Hodi FS, Flaherty KT, Kamm RD, Boland GM, Wong KK, Dornan D, Paweletz CP, Barbie DA. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018 02; 8(2):196-215. PMID: 29101162.
    Citations: 4     Fields:    
  15. Deng J, Wang ES, Jenkins RW, Li S, Dries R, Yates K, Chhabra S, Huang W, Liu H, Aref AR, Ivanova E, Paweletz CP, Bowden M, Zhou CW, Herter-Sprie GS, Sorrentino JA, Bisi JE, Lizotte PH, Merlino AA, Quinn MM, Bufe LE, Yang A, Zhang Y, Zhang H, Gao P, Chen T, Cavanaugh ME, Rode AJ, Haines E, Roberts PJ, Strum JC, Richards WG, Lorch JH, Parangi S, Gunda V, Boland GM, Bueno R, Palakurthi S, Freeman GJ, Ritz J, Haining WN, Sharpless NE, Arthanari H, Shapiro GI, Barbie DA, Gray NS, Wong KK. CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation. Cancer Discov. 2018 02; 8(2):216-233. PMID: 29101163.
    Citations: 4     Fields:    
  16. Yu L, Tomlinson JE, Alexander ST, Hensley K, Han CY, Dwyer D, Stolina M, Dean C, Goodman WG, Richards WG, Li X. Etelcalcetide, A Novel Calcimimetic, Prevents Vascular Calcification in A Rat Model of Renal Insufficiency with Secondary Hyperparathyroidism. Calcif Tissue Int. 2017 12; 101(6):641-653. PMID: 29038882.
    Citations: 3     Fields:    Translation:Animals
  17. Li X, Yu L, Asuncion F, Grisanti M, Alexander S, Hensley K, Han CY, Niu QT, Dwyer D, Villasenor K, Stolina M, Dean C, Ominsky MS, Ke HZ, Tomlinson JE, Richards WG. Etelcalcetide (AMG 416), a peptide agonist of the calcium-sensing receptor, preserved cortical bone structure and bone strength in subtotal nephrectomized rats with established secondary hyperparathyroidism. Bone. 2017 Dec; 105:163-172. PMID: 28867373.
    Citations: 2     Fields:    Translation:Animals
  18. Richards WG. Malignant pleural mesothelioma: predictors and staging. Ann Transl Med. 2017 Jun; 5(11):243. PMID: 28706911.
    Citations: 1     
  19. Muñoz-Castañeda JR, Herencia C, Pendón-Ruiz de Mier MV, Rodriguez-Ortiz ME, Diaz-Tocados JM, Vergara N, Martínez-Moreno JM, Salmerón MD, Richards WG, Felsenfeld A, Kuro-O M, Almadén Y, Rodríguez M. Differential regulation of renal Klotho and FGFR1 in normal and uremic rats. FASEB J. 2017 09; 31(9):3858-3867. PMID: 28515153.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  20. Zhang J, Gupte J, Gong Y, Weiszmann J, Zhang Y, Lee KJ, Richards WG, Li Y. Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action. EBioMedicine. 2017 Feb; 15:173-183. PMID: 28041926.
    Citations: 2     Fields:    Translation:AnimalsCells
  21. Rulifson IC, Collins P, Miao L, Nojima D, Lee KJ, Hardy M, Gupte J, Hensley K, Samayoa K, Cam C, Rottman JB, Ollmann M, Richards WG, Li Y. In Vitro and in Vivo Analyses Reveal Profound Effects of Fibroblast Growth Factor 16 as a Metabolic Regulator. J Biol Chem. 2017 02 03; 292(5):1951-1969. PMID: 28011645.
    Citations:    Fields:    Translation:HumansAnimalsCells
  22. de Almeida RM, Clendenon SG, Richards WG, Boedigheimer M, Damore M, Rossetti S, Harris PC, Herbert BS, Xu WM, Wandinger-Ness A, Ward HH, Glazier JA, Bacallao RL. Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD. Hum Genomics. 2016 11 21; 10(1):37. PMID: 27871310.
    Citations: 1     Fields:    Translation:HumansCells
  23. De Rienzo A, Cook RW, Wilkinson J, Gustafson CE, Amin W, Johnson CE, Oelschlager KM, Maetzold DJ, Stone JF, Feldman MD, Becich MJ, Yeap BY, Richards WG, Bueno R. Validation of a Gene Expression Test for Mesothelioma Prognosis in Formalin-Fixed Paraffin-Embedded Tissues. J Mol Diagn. 2017 01; 19(1):65-71. PMID: 27863259.
    Citations: 2     Fields:    Translation:HumansCells
  24. Awad MM, Jones RE, Liu H, Lizotte PH, Ivanova EV, Kulkarni M, Herter-Sprie GS, Liao X, Santos AA, Bittinger MA, Keogh L, Koyama S, Almonte C, English JM, Barlow J, Richards WG, Barbie DA, Bass AJ, Rodig SJ, Hodi FS, Wucherpfennig KW, Jänne PA, Sholl LM, Hammerman PS, Wong KK, Bueno R. Cytotoxic T Cells in PD-L1-Positive Malignant Pleural Mesotheliomas Are Counterbalanced by Distinct Immunosuppressive Factors. Cancer Immunol Res. 2016 12; 4(12):1038-1048. PMID: 27856426.
    Citations: 10     Fields:    Translation:HumansCells
  25. Lizotte PH, Ivanova EV, Awad MM, Jones RE, Keogh L, Liu H, Dries R, Almonte C, Herter-Sprie GS, Santos A, Feeney NB, Paweletz CP, Kulkarni MM, Bass AJ, Rustgi AK, Yuan GC, Kufe DW, Jänne PA, Hammerman PS, Sholl LM, Hodi FS, Richards WG, Bueno R, English JM, Bittinger MA, Wong KK. Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes. JCI Insight. 2016 09 08; 1(14):e89014. PMID: 27699239.
    Citations: 14     Fields:    Translation:HumansCells
  26. Lizotte PH, Jones RE, Keogh L, Ivanova E, Liu H, Awad MM, Hammerman PS, Gill RR, Richards WG, Barbie DA, Bass AJ, Bueno R, English JM, Bittinger M, Wong KK. Fine needle aspirate flow cytometric phenotyping characterizes immunosuppressive nature of the mesothelioma microenvironment. Sci Rep. 2016 08 19; 6:31745. PMID: 27539742.
    Citations: 5     Fields:    Translation:HumansCells
  27. Meerang M, Bérard K, Friess M, Bitanihirwe BK, Soltermann A, Vrugt B, Felley-Bosco E, Bueno R, Richards WG, Seifert B, Stahel R, Weder W, Opitz I. Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma. Mol Oncol. 2016 10; 10(8):1255-65. PMID: 27378628.
    Citations: 11     Fields:    Translation:HumansCells
  28. Florio M, Gunasekaran K, Stolina M, Li X, Liu L, Tipton B, Salimi-Moosavi H, Asuncion FJ, Li C, Sun B, Tan HL, Zhang L, Han CY, Case R, Duguay AN, Grisanti M, Stevens J, Pretorius JK, Pacheco E, Jones H, Chen Q, Soriano BD, Wen J, Heron B, Jacobsen FW, Brisan E, Richards WG, Ke HZ, Ominsky MS. A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair. Nat Commun. 2016 05 27; 7:11505. PMID: 27230681.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  29. Gill RR, Naidich DP, Mitchell A, Ginsberg M, Erasmus J, Armato SG, Straus C, Katz S, Patios D, Richards WG, Rusch VW. North American Multicenter Volumetric CT Study for Clinical Staging of Malignant Pleural Mesothelioma: Feasibility and Logistics of Setting Up a Quantitative Imaging Study. J Thorac Oncol. 2016 08; 11(8):1335-1344. PMID: 27180318.
    Citations: 8     Fields:    Translation:Humans
  30. Follo C, Barbone D, Richards WG, Bueno R, Broaddus VC. Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome. Autophagy. 2016 07 02; 12(7):1180-94. PMID: 27097020.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  31. Barbone D, Van Dam L, Follo C, Jithesh PV, Zhang SD, Richards WG, Bueno R, Fennell DA, Broaddus VC. Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma. PLoS One. 2016; 11(3):e0150044. PMID: 26982031.
    Citations: 3     Fields:    Translation:HumansCells
  32. Bueno R, Stawiski EW, Goldstein LD, Durinck S, De Rienzo A, Modrusan Z, Gnad F, Nguyen TT, Jaiswal BS, Chirieac LR, Sciaranghella D, Dao N, Gustafson CE, Munir KJ, Hackney JA, Chaudhuri A, Gupta R, Guillory J, Toy K, Ha C, Chen YJ, Stinson J, Chaudhuri S, Zhang N, Wu TD, Sugarbaker DJ, de Sauvage FJ, Richards WG, Seshagiri S. Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations. Nat Genet. 2016 Apr; 48(4):407-16. PMID: 26928227.
    Citations: 85     Fields:    Translation:HumansCells
  33. Koyama S, Akbay EA, Li YY, Herter-Sprie GS, Buczkowski KA, Richards WG, Gandhi L, Redig AJ, Rodig SJ, Asahina H, Jones RE, Kulkarni MM, Kuraguchi M, Palakurthi S, Fecci PE, Johnson BE, Janne PA, Engelman JA, Gangadharan SP, Costa DB, Freeman GJ, Bueno R, Hodi FS, Dranoff G, Wong KK, Hammerman PS. Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints. Nat Commun. 2016 Feb 17; 7:10501. PMID: 26883990.
    Citations: 153     Fields:    Translation:HumansAnimals
  34. Ng JM, Sugarbaker DJ, Bienfang DC, Richards WG, DaSilva MC, Frendl G, Hartigan PM. Perioperative Ischemic Optic Neuropathy Following Extrapleural Pneumonectomy. J Cardiothorac Vasc Anesth. 2016 Dec; 30(6):1645-1648. PMID: 27178100.
    Citations:    Fields:    Translation:Humans
  35. De Rienzo A, Archer MA, Yeap BY, Dao N, Sciaranghella D, Sideris AC, Zheng Y, Holman AG, Wang YE, Dal Cin PS, Fletcher JA, Rubio R, Croft L, Quackenbush J, Sugarbaker PE, Munir KJ, Battilana JR, Gustafson CE, Chirieac LR, Ching SM, Wong J, Tay LC, Rudd S, Hercus R, Sugarbaker DJ, Richards WG, Bueno R. Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma. Cancer Res. 2016 Jan 15; 76(2):319-28. PMID: 26554828.
    Citations: 8     Fields:    Translation:Humans
  36. Wang X, Gu L, Zhang Y, Sargent DJ, Richards W, Ganti AK, Crawford J, Cohen HJ, Stinchcombe T, Vokes E, Pang H. Validation of survival prognostic models for non-small-cell lung cancer in stage- and age-specific groups. Lung Cancer. 2015 Nov; 90(2):281-7. PMID: 26319317.
    Citations: 2     Fields:    Translation:Humans
  37. Hummel K, Richards W. Endoscopic treatment of gastroesophageal reflux disease. Surg Clin North Am. 2015 Jun; 95(3):653-67. PMID: 25965137.
    Citations: 2     Fields:    Translation:Humans
  38. Wu X, Zhang J, Ge H, Gupte J, Baribault H, Lee KJ, Lemon B, Coberly S, Gong Y, Pan Z, Rulifson IC, Gardner J, Richards WG, Li Y. Soluble CLEC2 Extracellular Domain Improves Glucose and Lipid Homeostasis by Regulating Liver Kupffer Cell Polarization. EBioMedicine. 2015 Mar; 2(3):214-24. PMID: 26151067.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  39. Baldini EH, Richards WG, Gill RR, Goodman BM, Winfrey OK, Eisen HM, Mak RH, Chen AB, Kozono DE, Bueno R, Sugarbaker DJ. Updated patterns of failure after multimodality therapy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2015 May; 149(5):1374-81. PMID: 25772281.
    Citations: 8     Fields:    Translation:Humans
  40. Nwogu CE, D'Cunha J, Pang H, Gu L, Wang X, Richards WG, Veit LJ, Demmy TL, Sugarbaker DJ, Kohman LJ, Swanson SJ. VATS lobectomy has better perioperative outcomes than open lobectomy: CALGB 31001, an ancillary analysis of CALGB 140202 (Alliance). Ann Thorac Surg. 2015 Feb; 99(2):399-405. PMID: 25499481.
    Citations: 25     Fields:    Translation:Humans
  41. Rulifson IC, Majeti JZ, Xiong Y, Hamburger A, Lee KJ, Miao L, Lu M, Gardner J, Gong Y, Wu H, Case R, Yeh WC, Richards WG, Baribault H, Li Y. Inhibition of secreted frizzled-related protein 5 improves glucose metabolism. Am J Physiol Endocrinol Metab. 2014 Dec 15; 307(12):E1144-52. PMID: 25370851.
    Citations: 1     Fields:    Translation:AnimalsCells
  42. Helmering J, Juan T, Li CM, Chhoa M, Baron W, Gyuris T, Richards WG, Turk JR, Lawrence J, Cosgrove PA, Busby J, Kim KW, Kaufman SA, Cummings C, Carlson G, Véniant MM, Lloyd DJ. A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice. Lipids Health Dis. 2014 Oct 31; 13:167. PMID: 25361754.
    Citations: 4     Fields:    Translation:Animals
  43. Capelletti M, Dodge ME, Ercan D, Hammerman PS, Park SI, Kim J, Sasaki H, Jablons DM, Lipson D, Young L, Stephens PJ, Miller VA, Lindeman NI, Munir KJ, Richards WG, Jänne PA. Identification of recurrent FGFR3-TACC3 fusion oncogenes from lung adenocarcinoma. Clin Cancer Res. 2014 Dec 15; 20(24):6551-8. PMID: 25294908.
    Citations: 28     Fields:    Translation:Humans
  44. Sugarbaker DJ, Richards WG, Bueno R. Extrapleural pneumonectomy in the treatment of epithelioid malignant pleural mesothelioma: novel prognostic implications of combined N1 and N2 nodal involvement based on experience in 529 patients. Ann Surg. 2014 Oct; 260(4):577-80; discussion 580-2. PMID: 25203873.
    Citations: 16     Fields:    Translation:Humans
  45. Meir T, Durlacher K, Pan Z, Amir G, Richards WG, Silver J, Naveh-Many T. Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription. Kidney Int. 2014 Dec; 86(6):1106-15. PMID: 24940803.
    Citations: 30     Fields:    Translation:AnimalsCells
  46. Guerrero F, Herencia C, Almadén Y, Martínez-Moreno JM, Montes de Oca A, Rodriguez-Ortiz ME, Diaz-Tocados JM, Canalejo A, Florio M, López I, Richards WG, Rodriguez M, Aguilera-Tejero E, Muñoz-Castañeda JR. TGF-ß prevents phosphate-induced osteogenesis through inhibition of BMP and Wnt/ß-catenin pathways. PLoS One. 2014; 9(2):e89179. PMID: 24586576.
    Citations: 9     Fields:    Translation:AnimalsCells
  47. De Rienzo A, Yeap BY, Cibas ES, Richards WG, Dong L, Gill RR, Sugarbaker DJ, Bueno R. Gene expression ratio test distinguishes normal lung from lung tumors in solid tissue and FNA biopsies. J Mol Diagn. 2014 Mar; 16(2):267-72. PMID: 24412526.
    Citations: 4     Fields:    Translation:Humans
  48. Chirieac LR, Barletta JA, Yeap BY, Richards WG, Tilleman T, Bueno R, Baldini EH, Godleski J, Sugarbaker DJ. Clinicopathologic characteristics of malignant mesotheliomas arising in patients with a history of radiation for Hodgkin and non-Hodgkin lymphoma. J Clin Oncol. 2013 Dec 20; 31(36):4544-9. PMID: 24248693.
    Citations: 12     Fields:    Translation:Humans
  49. Burt BM, Ali SO, DaSilva MC, Yeap BY, Richards WG, Baldini EH, Sugarbaker DJ. Clinical indications and results after chest wall resection for recurrent mesothelioma. J Thorac Cardiovasc Surg. 2013 Dec; 146(6):1373-9; discussion 1379-80. PMID: 24113019.
    Citations: 1     Fields:    Translation:Humans
  50. Capasso G, Geibel PJ, Damiano S, Jaeger P, Richards WG, Geibel JP. The calcium sensing receptor modulates fluid reabsorption and acid secretion in the proximal tubule. Kidney Int. 2013 Aug; 84(2):277-84. PMID: 23615500.
    Citations: 11     Fields:    Translation:Animals
  51. De Rienzo A, Richards WG, Yeap BY, Coleman MH, Sugarbaker PE, Chirieac LR, Wang YE, Quackenbush J, Jensen RV, Bueno R. Sequential binary gene ratio tests define a novel molecular diagnostic strategy for malignant pleural mesothelioma. Clin Cancer Res. 2013 May 01; 19(9):2493-502. PMID: 23493352.
    Citations: 4     Fields:    Translation:HumansCells
  52. Sugarbaker DJ, Gill RR, Yeap BY, Wolf AS, DaSilva MC, Baldini EH, Bueno R, Richards WG. Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural mesothelioma undergoing surgical macroscopic complete resection. J Thorac Cardiovasc Surg. 2013 Apr; 145(4):955-963. PMID: 23434448.
    Citations: 26     Fields:    Translation:Humans
  53. Qian X, Yuan X, Vonderfecht S, Ge X, Lee J, Jurisch A, Zhang L, You A, Fitzpatrick VD, Williams A, Valente EG, Pretorius J, Stevens JL, Tipton B, Winters AG, Graham K, Harriss L, Baker DM, Damore M, Salimi-Moosavi H, Gao Y, Elkhal A, Paszty C, Simonet WS, Richards WG, Tullius SG. Inhibition of WISE preserves renal allograft function. J Am Soc Nephrol. 2013 Jan; 24(1):66-76. PMID: 23184054.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  54. Shalhoub V, Shatzen EM, Ward SC, Davis J, Stevens J, Bi V, Renshaw L, Hawkins N, Wang W, Chen C, Tsai MM, Cattley RC, Wronski TJ, Xia X, Li X, Henley C, Eschenberg M, Richards WG. FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality. J Clin Invest. 2012 Jul; 122(7):2543-53. PMID: 22728934.
    Citations: 88     Fields:    Translation:AnimalsCells
  55. Ke HZ, Richards WG, Li X, Ominsky MS. Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases. Endocr Rev. 2012 Oct; 33(5):747-83. PMID: 22723594.
    Citations: 85     Fields:    Translation:HumansAnimalsCells
  56. Rostas JW, Richards WO, Thompson LW. Improved rate of pancreatic fistula after distal pancreatectomy: parenchymal division with the use of saline-coupled radiofrequency ablation. HPB (Oxford). 2012 Aug; 14(8):560-4. PMID: 22762405.
    Citations: 3     Fields:    Translation:Humans
  57. Basseres DS, D'Alò F, Yeap BY, Löwenberg EC, Gonzalez DA, Yasuda H, Dayaram T, Kocher ON, Godleski JJ, Richards WG, Meyerson M, Kobayashi S, Tenen DG, Halmos B, Costa DB. Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing. Lung Cancer. 2012 Jul; 77(1):31-7. PMID: 22341411.
    Citations: 10     Fields:    Translation:HumansCells
  58. Gill RR, Richards WG, Yeap BY, Matsuoka S, Wolf AS, Gerbaudo VH, Bueno R, Sugarbaker DJ, Hatabu H. Epithelial malignant pleural mesothelioma after extrapleural pneumonectomy: stratification of survival with CT-derived tumor volume. AJR Am J Roentgenol. 2012 Feb; 198(2):359-63. PMID: 22268178.
    Citations: 14     Fields:    Translation:Humans
  59. Li X, Grisanti M, Fan W, Asuncion FJ, Tan HL, Dwyer D, Han CY, Yu L, Lee J, Lee E, Barrero M, Kurimoto P, Niu QT, Geng Z, Winters A, Horan T, Steavenson S, Jacobsen F, Chen Q, Haldankar R, Lavallee J, Tipton B, Daris M, Sheng J, Lu HS, Daris K, Deshpande R, Valente EG, Salimi-Moosavi H, Kostenuik PJ, Li J, Liu M, Li C, Lacey DL, Simonet WS, Ke HZ, Babij P, Stolina M, Ominsky MS, Richards WG. Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury. J Bone Miner Res. 2011 Nov; 26(11):2610-21. PMID: 21773994.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  60. Wolf AS, Richards WG, Jaklitsch MT, Gill R, Chirieac LR, Colson YL, Mohiuddin K, Mentzer SJ, Bueno R, Sugarbaker DJ, Swanson SJ. Lobectomy versus sublobar resection for small (2 cm or less) non-small cell lung cancers. Ann Thorac Surg. 2011 Nov; 92(5):1819-23; discussion 1824-5. PMID: 22051277.
    Citations: 33     Fields:    Translation:Humans
  61. Rostas JW, Mai TT, Richards WO. Gastric motility physiology and surgical intervention. Surg Clin North Am. 2011 Oct; 91(5):983-99. PMID: 21889025.
    Citations: 2     Fields:    Translation:Humans
  62. Haniu M, Horan T, Spahr C, Hui J, Fan W, Chen C, Richards WG, Lu HS. Human Dickkopf-1 (huDKK1) protein: characterization of glycosylation and determination of disulfide linkages in the two cysteine-rich domains. Protein Sci. 2011 Nov; 20(11):1802-13. PMID: 21805521.
    Citations: 6     Fields:    Translation:AnimalsCells
  63. Henley C, Yang Y, Davis J, Lu JY, Morony S, Fan W, Florio M, Sun B, Shatzen E, Pretorius JK, Richards WG, St Jean DJ, Fotsch C, Reagan JD. Discovery of a calcimimetic with differential effects on parathyroid hormone and calcitonin secretion. J Pharmacol Exp Ther. 2011 Jun; 337(3):681-91. PMID: 21422163.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  64. Sugarbaker DJ, Wolf AS, Chirieac LR, Godleski JJ, Tilleman TR, Jaklitsch MT, Bueno R, Richards WG. Clinical and pathological features of three-year survivors of malignant pleural mesothelioma following extrapleural pneumonectomy. Eur J Cardiothorac Surg. 2011 Aug; 40(2):298-303. PMID: 21310625.
    Citations: 16     Fields:    Translation:Humans
  65. Purwar R, Campbell J, Murphy G, Richards WG, Clark RA, Kupper TS. Resident memory T cells (T(RM)) are abundant in human lung: diversity, function, and antigen specificity. PLoS One. 2011 Jan 26; 6(1):e16245. PMID: 21298112.
    Citations: 93     Fields:    Translation:HumansCells
  66. De Rienzo A, Dong L, Yeap BY, Jensen RV, Richards WG, Gordon GJ, Sugarbaker DJ, Bueno R. Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma. Clin Cancer Res. 2011 Jan 15; 17(2):310-6. PMID: 21088255.
    Citations: 9     Fields:    Translation:HumansCells
  67. Heiland GR, Zwerina K, Baum W, Kireva T, Distler JH, Grisanti M, Asuncion F, Li X, Ominsky M, Richards W, Schett G, Zwerina J. Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression. Ann Rheum Dis. 2010 Dec; 69(12):2152-9. PMID: 20858621.
    Citations: 50     Fields:    Translation:AnimalsCells
  68. Wolf AS, Richards WG, Tilleman TR, Chirieac L, Hurwitz S, Bueno R, Sugarbaker DJ. Characteristics of malignant pleural mesothelioma in women. Ann Thorac Surg. 2010 Sep; 90(3):949-56; discussion 956. PMID: 20732523.
    Citations: 9     Fields:    Translation:Humans
  69. Mujoomdar AA, Tilleman TR, Richards WG, Bueno R, Sugarbaker DJ. Prevalence of in vitro chemotherapeutic drug resistance in primary malignant pleural mesothelioma: result in a cohort of 203 resection specimens. J Thorac Cardiovasc Surg. 2010 Aug; 140(2):352-5. PMID: 20653100.
    Citations: 7     Fields:    Translation:HumansCells
  70. Kim S, Richards WO. Long-term follow-up of the metabolic profiles in obese patients with type 2 diabetes mellitus after Roux-en-Y gastric bypass. Ann Surg. 2010 Jun; 251(6):1049-55. PMID: 20485144.
    Citations: 26     Fields:    Translation:Humans
  71. Bueno R, De Rienzo A, Dong L, Gordon GJ, Hercus CF, Richards WG, Jensen RV, Anwar A, Maulik G, Chirieac LR, Ho KF, Taillon BE, Turcotte CL, Hercus RG, Gullans SR, Sugarbaker DJ. Second generation sequencing of the mesothelioma tumor genome. PLoS One. 2010 May 13; 5(5):e10612. PMID: 20485525.
    Citations: 26     Fields:    Translation:HumansCells
  72. Richards WG, Godleski JJ, Yeap BY, Corson JM, Chirieac LR, Zellos L, Mujoomdar A, Jaklitsch MT, Bueno R, Sugarbaker DJ. Proposed adjustments to pathologic staging of epithelial malignant pleural mesothelioma based on analysis of 354 cases. Cancer. 2010 Mar 15; 116(6):1510-7. PMID: 20108310.
    Citations: 15     Fields:    Translation:Humans
  73. Landles C, Sathasivam K, Weiss A, Woodman B, Moffitt H, Finkbeiner S, Sun B, Gafni J, Ellerby LM, Trottier Y, Richards WG, Osmand A, Paganetti P, Bates GP. Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease. J Biol Chem. 2010 Mar 19; 285(12):8808-23. PMID: 20086007.
    Citations: 105     Fields:    Translation:AnimalsCells
  74. Wolf AS, Jacobson FL, Tilleman TR, Colson Y, Richards WG, Sugarbaker DJ. Managing the pneumonectomy space after extrapleural pneumonectomy: postoperative intrathoracic pressure monitoring. Eur J Cardiothorac Surg. 2010 Apr; 37(4):770-5. PMID: 20056433.
    Citations: 1     Fields:    Translation:Humans
  75. Babij P, Roudier M, Graves T, Han CY, Chhoa M, Li CM, Juan T, Morony S, Grisanti M, Li X, Yu L, Dwyer D, Lloyd DJ, Bass MB, Richards WG, Ebeling C, Amato J, Carlson G. New variants in the Enpp1 and Ptpn6 genes cause low BMD, crystal-related arthropathy, and vascular calcification. J Bone Miner Res. 2009 Sep; 24(9):1552-64. PMID: 19419305.
    Citations: 18     Fields:    Translation:AnimalsCells
  76. Tilleman TR, Richards WG, Zellos L, Johnson BE, Jaklitsch MT, Mueller J, Yeap BY, Mujoomdar AA, Ducko CT, Bueno R, Sugarbaker DJ. Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: a phase II prospective study. J Thorac Cardiovasc Surg. 2009 Aug; 138(2):405-11. PMID: 19619785.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  77. Allen JG, Lee MR, Han CY, Scherrer J, Flynn S, Boucher C, Zhao H, O'Connor AB, Roveto P, Bauer D, Graceffa R, Richards WG, Babij P. Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells. Bioorg Med Chem Lett. 2009 Sep 01; 19(17):4924-8. PMID: 19648005.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  78. Gordon GJ, Dong L, Yeap BY, Richards WG, Glickman JN, Edenfield H, Mani M, Colquitt R, Maulik G, Van Oss B, Sugarbaker DJ, Bueno R. Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma. J Natl Cancer Inst. 2009 May 06; 101(9):678-86. PMID: 19401544.
    Citations: 22     Fields:    Translation:Humans
  79. Zellos L, Richards WG, Capalbo L, Jaklitsch MT, Chirieac LR, Johnson BE, Bueno R, Sugarbaker DJ. A phase I study of extrapleural pneumonectomy and intracavitary intraoperative hyperthermic cisplatin with amifostine cytoprotection for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2009 Feb; 137(2):453-8. PMID: 19185169.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  80. Dong L, Bard AJ, Richards WG, Nitz MD, Theodorescu D, Bueno R, Gordon GJ. A gene expression ratio-based diagnostic test for bladder cancer. Adv Appl Bioinform Chem. 2009; 2:17-22. PMID: 21918612.
    Citations: 6     
  81. Richards WG. Recent advances in mesothelioma staging. Semin Thorac Cardiovasc Surg. 2009; 21(2):105-10. PMID: 19822281.
    Citations: 4     Fields:    Translation:HumansCells
  82. Koivunen JP, Mermel C, Zejnullahu K, Murphy C, Lifshits E, Holmes AJ, Choi HG, Kim J, Chiang D, Thomas R, Lee J, Richards WG, Sugarbaker DJ, Ducko C, Lindeman N, Marcoux JP, Engelman JA, Gray NS, Lee C, Meyerson M, Jänne PA. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res. 2008 Jul 01; 14(13):4275-83. PMID: 18594010.
    Citations: 272     Fields:    Translation:HumansCells
  83. Koivunen JP, Kim J, Lee J, Rogers AM, Park JO, Zhao X, Naoki K, Okamoto I, Nakagawa K, Yeap BY, Meyerson M, Wong KK, Richards WG, Sugarbaker DJ, Johnson BE, Jänne PA. Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients. Br J Cancer. 2008 Jul 22; 99(2):245-52. PMID: 18594528.
    Citations: 45     Fields:    Translation:HumansCells
  84. Neragi-Miandoab S, Richards WG, Sugarbaker DJ. Morbidity, mortality, mean survival, and the impact of histology on survival after pleurectomy in 64 patients with malignant pleural mesothelioma. Int J Surg. 2008 Aug; 6(4):293-7. PMID: 18585112.
    Citations: 4     Fields:    Translation:Humans
  85. Sugarbaker DJ, Richards WG, Gordon GJ, Dong L, De Rienzo A, Maulik G, Glickman JN, Chirieac LR, Hartman ML, Taillon BE, Du L, Bouffard P, Kingsmore SF, Miller NA, Farmer AD, Jensen RV, Gullans SR, Bueno R. Transcriptome sequencing of malignant pleural mesothelioma tumors. Proc Natl Acad Sci U S A. 2008 Mar 04; 105(9):3521-6. PMID: 18303113.
    Citations: 63     Fields:    Translation:HumansCells
  86. Neragi-Miandoab S, Linden PA, Ducko CT, Bueno R, Richards WG, Sugarbaker DJ, Jaklitsch MT. VATS pericardiotomy for patients with known malignancy and pericardial effusion: survival and prognosis of positive cytology and metastatic involvement of the pericardium: a case control study. Int J Surg. 2008 Apr; 6(2):110-4. PMID: 18329349.
    Citations: 3     Fields:    Translation:Humans
  87. Richards WG, Van Oss SB, Glickman JN, Chirieac LR, Yeap B, Dong L, Gordon GJ, Mercer H, Gill KK, Imrich A, Bueno R, Sugarbaker DJ. A microaliquoting technique for precise histological annotation and optimization of cell content in frozen tissue specimens. Biotech Histochem. 2007 Aug; 82(4-5):189-97. PMID: 17917854.
    Citations: 7     Fields:    Translation:Humans
  88. Torquati A, Wright K, Melvin W, Richards W. Effect of gastric bypass operation on Framingham and actual risk of cardiovascular events in class II to III obesity. J Am Coll Surg. 2007 May; 204(5):776-82; discussion 782-3. PMID: 17481482.
    Citations: 20     Fields:    Translation:Humans
  89. Sekhar N, Torquati A, Youssef Y, Wright JK, Richards WO. A comparison of 399 open and 568 laparoscopic gastric bypasses performed during a 4-year period. Surg Endosc. 2007 Apr; 21(4):665-8. PMID: 17285374.
    Citations: 26     Fields:    Translation:Humans
  90. Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G. Dickkopf-1 is a master regulator of joint remodeling. Nat Med. 2007 Feb; 13(2):156-63. PMID: 17237793.
    Citations: 322     Fields:    Translation:HumansAnimalsCells
  91. Jaklitsch MT, Herndon JE, DeCamp MM, Richards WG, Kumar P, Krasna MJ, Green MR, Sugarbaker DJ. Nodal downstaging predicts survival following induction chemotherapy for stage IIIA (N2) non-small cell lung cancer in CALGB protocol #8935. J Surg Oncol. 2006 Dec 01; 94(7):599-606. PMID: 17039491.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  92. Rothstein R, Filipi C, Caca K, Pruitt R, Mergener K, Torquati A, Haber G, Chen Y, Chang K, Wong D, Deviere J, Pleskow D, Lightdale C, Ades A, Kozarek R, Richards W, Lembo A. Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease: A randomized, sham-controlled trial. Gastroenterology. 2006 Sep; 131(3):704-12. PMID: 16952539.
    Citations: 36     Fields:    Translation:Humans
  93. Richards WG. Technology transfer is all about bringing in money. Nature. 2006 Jun 08; 441(7094):690. PMID: 16760952.
    Citations:    Fields:    
  94. Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, Kostenuik P, Lacey DL, Simonet WS, Bolon B, Qian X, Shalhoub V, Ominsky MS, Zhu Ke H, Li X, Richards WG. Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone. 2006 Oct; 39(4):754-66. PMID: 16730481.
    Citations: 139     Fields:    Translation:HumansAnimalsCells
  95. Torquati A, Richards WO, Holzman MD, Sharp KW. Laparoscopic myotomy for achalasia: predictors of successful outcome after 200 cases. Ann Surg. 2006 May; 243(5):587-91; discussion 591-3. PMID: 16632992.
    Citations: 35     Fields:    Translation:Humans
  96. Richards WG, Zellos L, Bueno R, Jaklitsch MT, Jänne PA, Chirieac LR, Yeap BY, Dekkers RJ, Hartigan PM, Capalbo L, Sugarbaker DJ. Phase I to II study of pleurectomy/decortication and intraoperative intracavitary hyperthermic cisplatin lavage for mesothelioma. J Clin Oncol. 2006 Apr 01; 24(10):1561-7. PMID: 16575008.
    Citations: 40     Fields:    Translation:HumansCTClinical Trials
  97. Baribault H, Danao J, Gupte J, Yang L, Sun B, Richards W, Tian H. The G-protein-coupled receptor GPR103 regulates bone formation. Mol Cell Biol. 2006 Jan; 26(2):709-17. PMID: 16382160.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  98. Zhang Y, Kilroy GE, Henagan TM, Prpic-Uhing V, Richards WG, Bannon AW, Mynatt RL, Gettys TW. Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin. FASEB J. 2005 Sep; 19(11):1482-91. PMID: 16126916.
    Citations: 36     Fields:    Translation:Animals
  99. Couceyro PR, Evans C, McKinzie A, Mitchell D, Dube M, Hagshenas L, White FJ, Douglass J, Richards WG, Bannon AW. Cocaine- and amphetamine-regulated transcript (CART) peptides modulate the locomotor and motivational properties of psychostimulants. J Pharmacol Exp Ther. 2005 Dec; 315(3):1091-100. PMID: 16099925.
    Citations: 17     Fields:    Translation:Animals
  100. Poulose BK, Holzman MD, Zhu Y, Smalley W, Richards WO, Wright JK, Melvin W, Griffin MR. National variations in morbid obesity and bariatric surgery use. J Am Coll Surg. 2005 Jul; 201(1):77-84. PMID: 15978447.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  101. Zhao X, Weir BA, LaFramboise T, Lin M, Beroukhim R, Garraway L, Beheshti J, Lee JC, Naoki K, Richards WG, Sugarbaker D, Chen F, Rubin MA, Jänne PA, Girard L, Minna J, Christiani D, Li C, Sellers WR, Meyerson M. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res. 2005 Jul 01; 65(13):5561-70. PMID: 15994928.
    Citations: 129     Fields:    Translation:HumansCells
  102. Gordon GJ, Rockwell GN, Godfrey PA, Jensen RV, Glickman JN, Yeap BY, Richards WG, Sugarbaker DJ, Bueno R. Validation of genomics-based prognostic tests in malignant pleural mesothelioma. Clin Cancer Res. 2005 Jun 15; 11(12):4406-14. PMID: 15958625.
    Citations: 18     Fields:    Translation:Humans
  103. Gordon GJ, Rockwell GN, Jensen RV, Rheinwald JG, Glickman JN, Aronson JP, Pottorf BJ, Nitz MD, Richards WG, Sugarbaker DJ, Bueno R. Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling. Am J Pathol. 2005 Jun; 166(6):1827-40. PMID: 15920167.
    Citations: 58     Fields:    Translation:HumansCells
  104. Dresler CM, Olak J, Herndon JE, Richards WG, Scalzetti E, Fleishman SB, Kernstine KH, Demmy T, Jablons DM, Kohman L, Daniel TM, Haasler GB, Sugarbaker DJ. Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion. Chest. 2005 Mar; 127(3):909-15. PMID: 15764775.
    Citations: 54     Fields:    Translation:HumansCTClinical Trials
  105. Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature. 2005 Mar 24; 434(7032):514-20. PMID: 15724149.
    Citations: 291     Fields:    Translation:HumansAnimalsCells
  106. Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, Hansen M, Schaefer E, Naoki K, Lader A, Richards W, Sugarbaker D, Husain AN, Christensen JG, Salgia R. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res. 2005 Feb 15; 65(4):1479-88. PMID: 15735036.
    Citations: 177     Fields:    Translation:HumansCells
  107. Richards WO, Torquati A, Lutfi R. The current treatment of achalasia. Adv Surg. 2005; 39:285-314. PMID: 16250557.
    Citations: 3     Fields:    Translation:Humans
  108. Bentires-Alj M, Paez JG, David FS, Keilhack H, Halmos B, Naoki K, Maris JM, Richardson A, Bardelli A, Sugarbaker DJ, Richards WG, Du J, Girard L, Minna JD, Loh ML, Fisher DE, Velculescu VE, Vogelstein B, Meyerson M, Sellers WR, Neel BG. Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia. Cancer Res. 2004 Dec 15; 64(24):8816-20. PMID: 15604238.
    Citations: 143     Fields:    Translation:HumansCells
  109. Richards WO, Torquati A, Holzman MD, Khaitan L, Byrne D, Lutfi R, Sharp KW. Heller myotomy versus Heller myotomy with Dor fundoplication for achalasia: a prospective randomized double-blind clinical trial. Ann Surg. 2004 Sep; 240(3):405-12; discussion 412-5. PMID: 15319712.
    Citations: 130     Fields:    Translation:HumansCTClinical Trials
  110. Krop I, Player A, Tablante A, Taylor-Parker M, Lahti-Domenici J, Fukuoka J, Batra SK, Papadopoulos N, Richards WG, Sugarbaker DJ, Wright RL, Shim J, Stamey TA, Sellers WR, Loda M, Meyerson M, Hruban R, Jen J, Polyak K. Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types. Mol Cancer Res. 2004 Sep; 2(9):489-94. PMID: 15383627.
    Citations: 20     Fields:    Translation:HumansCells
  111. Sugarbaker DJ, Jaklitsch MT, Bueno R, Richards W, Lukanich J, Mentzer SJ, Colson Y, Linden P, Chang M, Capalbo L, Oldread E, Neragi-Miandoab S, Swanson SJ, Zellos LS. Prevention, early detection, and management of complications after 328 consecutive extrapleural pneumonectomies. J Thorac Cardiovasc Surg. 2004 Jul; 128(1):138-46. PMID: 15224033.
    Citations: 46     Fields:    Translation:Humans
  112. Richards WG, Grant GH, Harrison KN. Combating bioterrorism with personal computers. J Mol Graph Model. 2004 Jul; 22(6):473-8. PMID: 15182806.
    Citations: 1     Fields:    Translation:HumansCells
  113. Wei S, Feng Y, Che FY, Pan H, Mzhavia N, Devi LA, McKinzie AA, Levin N, Richards WG, Fricker LD. Obesity and diabetes in transgenic mice expressing proSAAS. J Endocrinol. 2004 Mar; 180(3):357-68. PMID: 15012590.
    Citations: 20     Fields:    Translation:Animals
  114. Albarado DC, McClaine J, Stephens JM, Mynatt RL, Ye J, Bannon AW, Richards WG, Butler AA. Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice. Endocrinology. 2004 Jan; 145(1):243-52. PMID: 14551222.
    Citations: 38     Fields:    Translation:AnimalsCells
  115. Powitzky ES, Khaitan L, Garrett CG, Richards WO, Courey M. Symptoms, quality of life, videolaryngoscopy, and twenty-four-hour triple-probe pH monitoring in patients with typical and extraesophageal reflux. Ann Otol Rhinol Laryngol. 2003 Oct; 112(10):859-65. PMID: 14587976.
    Citations: 2     Fields:    Translation:Humans
  116. Gordon GJ, Richards WG, Sugarbaker DJ, Jaklitsch MT, Bueno R. A prognostic test for adenocarcinoma of the lung from gene expression profiling data. Cancer Epidemiol Biomarkers Prev. 2003 Sep; 12(9):905-10. PMID: 14504202.
    Citations: 18     Fields:    Translation:Humans
  117. Zhang Q, Murcia NS, Chittenden LR, Richards WG, Michaud EJ, Woychik RP, Yoder BK. Loss of the Tg737 protein results in skeletal patterning defects. Dev Dyn. 2003 May; 227(1):78-90. PMID: 12701101.
    Citations: 54     Fields:    Translation:Animals
  118. Richards WO, Houston HL, Torquati A, Khaitan L, Holzman MD, Sharp KW. Paradigm shift in the management of gastroesophageal reflux disease. Ann Surg. 2003 May; 237(5):638-47; discussion 648-9. PMID: 12724630.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  119. Gordon GJ, Jensen RV, Hsiao LL, Gullans SR, Blumenstock JE, Richards WG, Jaklitsch MT, Sugarbaker DJ, Bueno R. Using gene expression ratios to predict outcome among patients with mesothelioma. J Natl Cancer Inst. 2003 Apr 16; 95(8):598-605. PMID: 12697852.
    Citations: 38     Fields:    Translation:Humans
  120. Powell CA, Spira A, Derti A, DeLisi C, Liu G, Borczuk A, Busch S, Sahasrabudhe S, Chen Y, Sugarbaker D, Bueno R, Richards WG, Brody JS. Gene expression in lung adenocarcinomas of smokers and nonsmokers. Am J Respir Cell Mol Biol. 2003 Aug; 29(2):157-62. PMID: 12600827.
    Citations: 27     Fields:    Translation:Humans
  121. Powell CA, Bueno R, Borczuk AC, Caracta CF, Richards WG, Sugarbaker DJ, Brody JS. Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokers. Lung Cancer. 2003 Jan; 39(1):23-9. PMID: 12499090.
    Citations: 6     Fields:    Translation:HumansCells
  122. Byrne JG, Karavas AN, Colson YL, Bueno R, Richards WG, Sugarbaker DJ, Goldhaber SZ. Cardiac decortication (epicardiectomy) for occult constrictive cardiac physiology after left extrapleural pneumonectomy. Chest. 2002 Dec; 122(6):2256-9. PMID: 12475875.
    Citations: 3     Fields:    Translation:Humans
  123. Naoki K, Chen TH, Richards WG, Sugarbaker DJ, Meyerson M. Missense mutations of the BRAF gene in human lung adenocarcinoma. Cancer Res. 2002 Dec 01; 62(23):7001-3. PMID: 12460919.
    Citations: 89     Fields:    Translation:Humans
  124. Sun B, Fan W, Balciunas A, Cooper JK, Bitan G, Steavenson S, Denis PE, Young Y, Adler B, Daugherty L, Manoukian R, Elliott G, Shen W, Talvenheimo J, Teplow DB, Haniu M, Haldankar R, Wypych J, Ross CA, Citron M, Richards WG. Polyglutamine repeat length-dependent proteolysis of huntingtin. Neurobiol Dis. 2002 Oct; 11(1):111-22. PMID: 12460551.
    Citations: 18     Fields:    Translation:AnimalsCells
  125. Gordon GJ, Jensen RV, Hsiao LL, Gullans SR, Blumenstock JE, Ramaswamy S, Richards WG, Sugarbaker DJ, Bueno R. Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma. Cancer Res. 2002 Sep 01; 62(17):4963-7. PMID: 12208747.
    Citations: 103     Fields:    Translation:Humans
  126. Gordon GJ, Appasani K, Parcells JP, Mukhopadhyay NK, Jaklitsch MT, Richards WG, Sugarbaker DJ, Bueno R. Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma. Carcinogenesis. 2002 Jun; 23(6):1017-24. PMID: 12082024.
    Citations: 17     Fields:    Translation:HumansCells
  127. Khaitan L, Houston H, Sharp K, Holzman M, Richards W. Laparoscopic paraesophageal hernia repair has an acceptable recurrence rate. Am Surg. 2002 Jun; 68(6):546-51; discussion 551-2. PMID: 12079137.
    Citations: 21     Fields:    Translation:HumansPHPublic Health
  128. Gordon GJ, Chen CJ, Jaklitsch MT, Richards WG, Sugarbaker DJ, Bueno R. Detection and quantification of SV40 large T-antigen DNA in mesothelioma tissues and cell lines. Oncol Rep. 2002 May-Jun; 9(3):631-4. PMID: 11956641.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  129. Sharp KW, Khaitan L, Scholz S, Holzman MD, Richards WO. 100 consecutive minimally invasive Heller myotomies: lessons learned. Ann Surg. 2002 May; 235(5):631-8; discussion 638-9. PMID: 11981208.
    Citations: 49     Fields:    Translation:Humans
  130. Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, Loda M, Weber G, Mark EJ, Lander ES, Wong W, Johnson BE, Golub TR, Sugarbaker DJ, Meyerson M. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13790-5. PMID: 11707567.
    Citations: 587     Fields:    Translation:Humans
  131. Jaklitsch MT, Mery CM, Lukanich JM, Richards WG, Bueno R, Swanson SJ, Mentzer SJ, Davis BD, Allred EN, Sugarbaker DJ. Sequential thoracic metastasectomy prolongs survival by re-establishing local control within the chest. J Thorac Cardiovasc Surg. 2001 Apr; 121(4):657-67. PMID: 11279405.
    Citations: 14     Fields:    Translation:Humans
  132. Bueno R, Richards WG, Swanson SJ, Jaklitsch MT, Lukanich JM, Mentzer SJ, Sugarbaker DJ. Nodal stage after induction therapy for stage IIIA lung cancer determines patient survival. Ann Thorac Surg. 2000 Dec; 70(6):1826-31. PMID: 11156079.
    Citations: 22     Fields:    Translation:Humans
  133. Clements RH, Reddy S, Holzman MD, Sharp KW, Olsen D, Holcomb GW, Richards WO. Incidence and significance of pneumomediastinum after laparoscopic esophageal surgery. Surg Endosc. 2000 Jun; 14(6):553-5. PMID: 10890964.
    Citations: 2     Fields:    Translation:Humans
  134. Torres CM, Wang HH, Turner JR, Richards W, Sugarbaker D, Shahsafaei A, Odze RD. Pathologic prognostic factors in esophageal squamous cell carcinoma: a follow-up study of 74 patients with or without preoperative chemoradiation therapy. Mod Pathol. 1999 Oct; 12(10):961-8. PMID: 10530561.
    Citations: 11     Fields:    Translation:Humans
  135. Rose DM, Delbeke D, Beauchamp RD, Chapman WC, Sandler MP, Sharp KW, Richards WO, Wright JK, Frexes ME, Pinson CW, Leach SD. 18Fluorodeoxyglucose-positron emission tomography in the management of patients with suspected pancreatic cancer. Ann Surg. 1999 May; 229(5):729-37; discussion 737-8. PMID: 10235532.
    Citations: 41     Fields:    Translation:HumansCTClinical Trials
  136. Glickman JN, Torres C, Wang HH, Turner JR, Shahsafaei A, Richards WG, Sugarbaker DJ, Odze RD. The prognostic significance of lymph node micrometastasis in patients with esophageal carcinoma. Cancer. 1999 Feb 15; 85(4):769-78. PMID: 10091753.
    Citations: 18     Fields:    Translation:Humans
  137. Torres C, Turner JR, Wang HH, Richards W, Sugarbaker D, Shahsafaei A, Odze RD. Pathologic prognostic factors in Barrett's associated adenocarcinoma: a follow-up study of 96 patients. Cancer. 1999 Feb 01; 85(3):520-8. PMID: 10091725.
    Citations: 9     Fields:    Translation:Humans
  138. Salgia R, Li JL, Ewaniuk DS, Wang YB, Sattler M, Chen WC, Richards W, Pisick E, Shapiro GI, Rollins BJ, Chen LB, Griffin JD, Sugarbaker DJ. Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility. Oncogene. 1999 Jan 07; 18(1):67-77. PMID: 9926921.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  139. Sugarbaker DJ, Flores RM, Jaklitsch MT, Richards WG, Strauss GM, Corson JM, DeCamp MM, Swanson SJ, Bueno R, Lukanich JM, Baldini EH, Mentzer SJ. Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients. J Thorac Cardiovasc Surg. 1999 Jan; 117(1):54-63; discussion 63-5. PMID: 9869758.
    Citations: 128     Fields:    Translation:Humans
  140. Kwiatkowski DJ, Harpole DH, Godleski J, Herndon JE, Shieh DB, Richards W, Blanco R, Xu HJ, Strauss GM, Sugarbaker DJ. Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications. J Clin Oncol. 1998 Jul; 16(7):2468-77. PMID: 9667266.
    Citations: 24     Fields:    Translation:Humans
  141. Swanson SJ, Mentzer SJ, DeCamp MM, Bueno R, Richards WG, Ingenito EP, Reilly JJ, Sugarbaker DJ. No-cut thoracoscopic lung plication: a new technique for lung volume reduction surgery. J Am Coll Surg. 1997 Jul; 185(1):25-32. PMID: 9208957.
    Citations: 5     Fields:    Translation:Humans
  142. Sugarbaker DJ, Richards WG, Garcia JP. Extrapleural pneumonectomy for malignant mesothelioma. Adv Surg. 1997; 31:253-71. PMID: 9408497.
    Citations:    Fields:    Translation:Humans
  143. Sugarbaker DJ, Garcia JP, Richards WG, Harpole DH, Healy-Baldini E, DeCamp MM, Mentzer SJ, Liptay MJ, Strauss GM, Swanson SJ. Extrapleural pneumonectomy in the multimodality therapy of malignant pleural mesothelioma. Results in 120 consecutive patients. Ann Surg. 1996 Sep; 224(3):288-94; discussion 294-6. PMID: 8813257.
    Citations: 29     Fields:    Translation:HumansCTClinical Trials
  144. Harpole DH, Richards WG, Herndon JE, Sugarbaker DJ. Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer. Ann Thorac Surg. 1996 May; 61(5):1470-6. PMID: 8633961.
    Citations: 16     Fields:    Translation:Humans
  145. Anderson IC, Sugarbaker DJ, Ganju RK, Tsarwhas DG, Richards WG, Sunday M, Kobzik L, Shipp MA. Stromelysin-3 is overexpressed by stromal elements in primary non-small cell lung cancers and regulated by retinoic acid in pulmonary fibroblasts. Cancer Res. 1995 Sep 15; 55(18):4120-6. PMID: 7664289.
    Citations: 12     Fields:    Translation:HumansCells
  146. Richards WG, Stamler JS, Kobzik L, Sugarbaker DJ. Role of nitric oxide in human esophageal circular smooth muscle in vitro. J Thorac Cardiovasc Surg. 1995 Jul; 110(1):157-64. PMID: 7541879.
    Citations: 3     Fields:    Translation:Humans
  147. Richards WO, Garrard CL, Allos SH, Bradshaw LA, Staton DJ, Wikswo JP. Noninvasive diagnosis of mesenteric ischemia using a SQUID magnetometer. Ann Surg. 1995 Jun; 221(6):696-704; discussion 704-5. PMID: 7794074.
    Citations: 18     Fields:    Translation:Animals
  148. Harpole DH, Marks JR, Richards WG, Herndon JE, Sugarbaker DJ. Localized adenocarcinoma of the lung: oncogene expression of erbB-2 and p53 in 150 patients. Clin Cancer Res. 1995 Jun; 1(6):659-64. PMID: 9816029.
    Citations: 4     Fields:    Translation:Humans
  149. Shapiro GI, Edwards CD, Kobzik L, Godleski J, Richards W, Sugarbaker DJ, Rollins BJ. Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines. Cancer Res. 1995 Feb 01; 55(3):505-9. PMID: 7834618.
    Citations: 58     Fields:    Translation:HumansCells
  150. Richards WG, Sugarbaker DJ. Neuronal control of esophageal function. Chest Surg Clin N Am. 1995 Feb; 5(1):157-71. PMID: 7743145.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  151. Eslami MH, Richards WG, Sugarbaker DJ. Esophageal physiology. Chest Surg Clin N Am. 1994 Nov; 4(4):635-52. PMID: 7859002.
    Citations:    Fields:    Translation:Humans
  152. Richards WO, Golzarian J, Wasudev N, Sawyers JL. Reverse phasic contractions are present in antiperistaltic jejunal limbs up to twenty-one years postoperatively. J Am Coll Surg. 1994 Jun; 178(6):557-63. PMID: 8193748.
    Citations: 1     Fields:    Translation:Humans
  153. Gaston B, Drazen JM, Jansen A, Sugarbaker DA, Loscalzo J, Richards W, Stamler JS. Relaxation of human bronchial smooth muscle by S-nitrosothiols in vitro. J Pharmacol Exp Ther. 1994 Feb; 268(2):978-84. PMID: 7906736.
    Citations: 31     Fields:    Translation:HumansCells
  154. Sugarbaker DJ, Kearney DJ, Richards WG. Esophageal physiology and pathophysiology. Surg Clin North Am. 1993 Dec; 73(6):1101-18. PMID: 8248829.
    Citations: 4     Fields:    Translation:Humans
  155. Sugarbaker DJ, Strauss GM, Lynch TJ, Richards W, Mentzer SJ, Lee TH, Corson JM, Antman KH. Node status has prognostic significance in the multimodality therapy of diffuse, malignant mesothelioma. J Clin Oncol. 1993 Jun; 11(6):1172-8. PMID: 8501504.
    Citations: 18     Fields:    Translation:Humans
  156. Geer RJ, Richards WO, O'Dorisio TM, Woltering EO, Williams S, Rice D, Abumrad NN. Efficacy of octreotide acetate in treatment of severe postgastrectomy dumping syndrome. Ann Surg. 1990 Dec; 212(6):678-87. PMID: 2256759.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  157. Sharp KW, Ross CB, Halter SA, Morrison JG, Richards WO, Williams LF, Sawyers JL. Pancreatoduodenectomy with pyloric preservation for carcinoma of the pancreas: a cautionary note. Surgery. 1989 May; 105(5):645-53. PMID: 2650006.
    Citations: 18     Fields:    Translation:Humans
  158. Richards WO, Williams LF. Obstruction of the large and small intestine. Surg Clin North Am. 1988 Apr; 68(2):355-76. PMID: 3279551.
    Citations: 13     Fields:    Translation:Humans
  159. Richards WO, Webb WA, Morris SJ, Davis RC, McDaniel L, Jones L, Littauer S. Patient management after endoscopic removal of the cancerous colon adenoma. Ann Surg. 1987 Jun; 205(6):665-72. PMID: 3592809.
    Citations: 10     Fields:    Translation:Humans
  160. Warren WD, Millikan WJ, Henderson JM, Abu-Elmagd KM, Galloway JR, Shires GT, Richards WO, Salam AA, Kutner MH. Splenopancreatic disconnection. Improved selectivity of distal splenorenal shunt. Ann Surg. 1986 Oct; 204(4):346-55. PMID: 3532968.
    Citations: 15     Fields:    Translation:Humans
  161. Richards WO, Scovill W, Shin B, Reed W. Acute renal failure associated with increased intra-abdominal pressure. Ann Surg. 1983 Feb; 197(2):183-7. PMID: 6600601.
    Citations: 47     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.