Harvard Catalyst Profiles

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Gladys N Pachas, M.D.

Title
Institution
Department
Address

Biography
awards and honors
1997 - 2000
Excellent Health Coverage & Health Indicators
2000
Special Recognition: Implementation of Model of Integral Care of the Children and women’s Health
2008
Fellowship & Travel award: 18th Annual Meeting
2009
Partners in Excellence Award, Center for Addiction Medicine
2010
Clinical Research Day 2010, Departmental Award-Psychiatry
2010
(New Clinical Drug Evaluation Unit). New Investigator Award 2010
2011
Travel Award: 2011 NHSN International Scientific Conference
2011
Fellowship & Travel Award: Summer Training Program 2011
2012
Fellowship & Travel Award: 2012 Workshop on Clinical Trials in Psychopharmacology
2014
Tobacco-Related Health Disparities fellowship and travel award to the 2014 SRNT conference Seattle
2014
Partners in Excellence Team Award, Center for Addiction Medicine

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gilman JM, Schuster RM, Potter KW, Schmitt W, Wheeler G, Pachas GN, Hickey S, Cooke ME, Dechert A, Plummer R, Tervo-Clemmens B, Schoenfeld DA, Evins AE. Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults: A Randomized Clinical Trial. JAMA Netw Open. 2022 Mar 01; 5(3):e222106. PMID: 35302633.
    Citations:    Fields:    
  2. Gilman JM, Schmitt WA, Potter K, Kendzior B, Pachas GN, Hickey S, Makary M, Huestis MA, Evins AE. Correction to: Identification of ?9-tetrahydrocannabinol (THC) impairment using functional brain imaging. Neuropsychopharmacology. 2022 Feb 28. PMID: 35228659.
    Citations:    Fields:    
  3. Gilman JM, Schmitt WA, Potter K, Kendzior B, Pachas GN, Hickey S, Makary M, Huestis MA, Evins AE. Identification of ?9-tetrahydrocannabinol (THC) impairment using functional brain imaging. Neuropsychopharmacology. 2022 03; 47(4):944-952. PMID: 34999737.
    Citations:    Fields:    Translation:HumansAnimals
  4. Schnitzer K, Maravic MC, Arntz D, Phillips NL, Pachas G, Evins AE, Fetters M. Integrated Smoking Cessation for Smokers With Serious Mental Illness: Protocol for a Convergent Mixed Methods Implementation Evaluation Study. JMIR Res Protoc. 2021 Jul 27; 10(7):e25390. PMID: 34313603.
    Citations:    
  5. Schnitzer K, Cather C, Zvonar V, Dechert A, Plummer R, Lowman K, Pachas G, Potter K, Evins AE. Patient Experience and Predictors of Improvement in a Group Behavioral and Educational Intervention for Individuals With Diabetes and Serious Mental Illness: Mixed Methods Case Study. J Particip Med. 2021 Feb 12; 13(1):e21934. PMID: 33576747.
    Citations:    
  6. Schuster RM, Potter K, Lamberth E, Rychik N, Hareli M, Allen S, Broos HC, Mustoe A, Gilman JM, Pachas G, Evins AE. Alcohol substitution during one month of cannabis abstinence among non-treatment seeking youth. Prog Neuropsychopharmacol Biol Psychiatry. 2021 04 20; 107:110205. PMID: 33309538.
    Citations: 2     Fields:    Translation:Humans
  7. Gilman JM, Yücel MA, Pachas GN, Potter K, Levar N, Broos H, Manghis EM, Schuster RM, Evins AE. Delta-9-tetrahydrocannabinol intoxication is associated with increased prefrontal activation as assessed with functional near-infrared spectroscopy: A report of a potential biomarker of intoxication. Neuroimage. 2019 08 15; 197:575-585. PMID: 31075393.
    Citations: 2     Fields:    Translation:Humans
  8. Otto MW, Pachas GN, Cather C, Hoeppner SS, Moshier SJ, Hearon BA, Ward HB, Laffer AB, Smits JAJ, Evins AE. A placebo-controlled randomized trial of D-cycloserine augmentation of cue exposure therapy for smoking cessation. Cogn Behav Ther. 2019 01; 48(1):65-76. PMID: 30111253.
    Citations: 3     Fields:    Translation:Humans
  9. Schuster RM, Pachas GN, Stoeckel L, Cather C, Nadal M, Mischoulon D, Schoenfeld DA, Zhang H, Ulysse C, Dodds EB, Sobolewski S, Hudziak V, Hanly A, Fava M, Evins AE. Phase IIb Trial of an a7 Nicotinic Receptor Partial Agonist With and Without Nicotine Patch for Withdrawal-Associated Cognitive Deficits and Tobacco Abstinence. J Clin Psychopharmacol. 2018 Aug; 38(4):307-316. PMID: 29912798.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  10. Gilman JM, Radoman M, Schuster RM, Pachas G, Azzouz N, Fava M, Evins AE. Anterior insula activation during inhibition to smoking cues is associated with ability to maintain tobacco abstinence. Addict Behav Rep. 2018 Jun; 7:40-46. PMID: 29450255.
    Citations: 6     
  11. Janes AC, Gilman JM, Frederick BB, Radoman M, Pachas G, Fava M, Evins AE. Salience network coupling is linked to both tobacco smoking and symptoms of attention deficit hyperactivity disorder (ADHD). Drug Alcohol Depend. 2018 01 01; 182:93-97. PMID: 29175464.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  12. Keles HO, Radoman M, Pachas GN, Evins AE, Gilman JM. Using Functional Near-Infrared Spectroscopy to Measure Effects of Delta 9-Tetrahydrocannabinol on Prefrontal Activity and Working Memory in Cannabis Users. Front Hum Neurosci. 2017; 11:488. PMID: 29066964.
    Citations: 7     
  13. Janes AC, Gilman JM, Radoman M, Pachas G, Fava M, Evins AE. Revisiting the role of the insula and smoking cue-reactivity in relapse: A replication and extension of neuroimaging findings. Drug Alcohol Depend. 2017 10 01; 179:8-12. PMID: 28735078.
    Citations: 19     Fields:    Translation:Humans
  14. Cather C, Pachas GN, Cieslak KM, Evins AE. Achieving Smoking Cessation in Individuals with Schizophrenia: Special Considerations. CNS Drugs. 2017 Jun; 31(6):471-481. PMID: 28550660.
    Citations: 29     Fields:    Translation:Humans
  15. Cather C, Hoeppner S, Pachas G, Pratt S, Achtyes E, Cieslak KM, Evins AE. Improved Depressive Symptoms in Adults with Schizophrenia During a Smoking Cessation Attempt with Varenicline and Behavioral Therapy. J Dual Diagn. 2017 Jul-Sep; 13(3):168-178. PMID: 28414583.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  16. Schuster RM, Cather C, Pachas GN, Zhang H, Cieslak KM, Hoeppner SS, Schoenfeld D, Evins AE. Predictors of tobacco abstinence in outpatient smokers with schizophrenia or bipolar disorder treated with varenicline and cognitive behavioral smoking cessation therapy. Addict Behav. 2017 08; 71:89-95. PMID: 28285208.
    Citations: 5     Fields:    Translation:Humans
  17. Allen SI, Foulds J, Pachas GN, Veldheer S, Cather C, Azzouz N, Hrabovsky S, Hameed A, Yingst J, Hammett E, Modesto J, Krebs NM, Zhu J, Liao J, Muscat JE, Richie J, Evins AE. A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol. BMC Public Health. 2017 01 19; 17(1):100. PMID: 28103841.
    Citations: 10     Fields:    Translation:HumansAnimals
  18. Evins AE, Hoeppner SS, Schoenfeld DA, Hoeppner BB, Cather C, Pachas GN, Cieslak KM, Maravic MC. Maintenance pharmacotherapy normalizes the relapse curve in recently abstinent tobacco smokers with schizophrenia and bipolar disorder. Schizophr Res. 2017 05; 183:124-129. PMID: 27956009.
    Citations: 3     Fields:    Translation:Humans
  19. Thorndike AN, Achtyes ED, Cather C, Pratt S, Pachas GN, Hoeppner SS, Evins AE. Weight gain and 10-year cardiovascular risk with sustained tobacco abstinence in smokers with serious mental illness: a subgroup analysis of a randomized trial. J Clin Psychiatry. 2016 Mar; 77(3):e320-6. PMID: 27046320.
    Citations: 7     Fields:    Translation:Humans
  20. Pachas GN, Gilman J, Orr SP, Hoeppner B, Carlini SV, Grasser EB, Loebl T, Nino J, Pitman RK, Evins AE. Erratum to: Single dose propranolol does not affect physiologic or emotional reactivity to smoking cues. Psychopharmacology (Berl). 2015 Jun; 232(11):2029. PMID: 25877745.
    Citations: 1     Fields:    
  21. Pachas GN, Gilman J, Orr SP, Hoeppner B, Carlini SV, Grasser EB, Loebl T, Nino J, Pitman RK, Evins AE. Single dose propranolol does not affect physiologic or emotional reactivity to smoking cues. Psychopharmacology (Berl). 2015 May; 232(9):1619-28. PMID: 25413896.
    Citations: 20     Fields:    Translation:Humans
  22. Barake M, Evins AE, Stoeckel L, Pachas GN, Nachtigall LB, Miller KK, Biller BM, Tritos NA, Klibanski A. Investigation of impulsivity in patients on dopamine agonist therapy for hyperprolactinemia: a pilot study. Pituitary. 2014 Apr; 17(2):150-6. PMID: 23504371.
    Citations: 13     Fields:    Translation:Humans
  23. Evins AE, Cather C, Pratt SA, Pachas GN, Hoeppner SS, Goff DC, Achtyes ED, Ayer D, Schoenfeld DA. Maintenance treatment with varenicline for smoking cessation in patients with schizophrenia and bipolar disorder: a randomized clinical trial. JAMA. 2014 Jan 08; 311(2):145-54. PMID: 24399553.
    Citations: 88     Fields:    Translation:Humans
  24. Pachas, G.N., Schuman-Olivier, Z, Hoeppner, S, Grasser, E.B., Daigneault, J.F., and Evins, A.E. Massachusetts General Hospital Clinical Research Day on October 2012 and at the Society for Research on Nicotine and Tobacco 2013 Conference, Boston, MA. Comparison of the Effect of mindfulness and cognitive behavioral therapy for smoking cessation on physiological responses to smoking cues and craving. 2013.
  25. Schuman-Olivier, Z, MD; Pachas, Gladys N, MD; Hoeppner, Bettina, PhD; Evins, A. Eden, MD, MPH . Society for Research on Nicotine and Tobacco 2013 Conference, Boston, MA. A Randomized Controlled Trial of Mindfulness Training for Smokers. 2013.
  26. A. Eden Evins; Corinne Cather; Sarah Pratt; Gladys N Pachas; Susanne Hoeppner; Eric Achtyes; David Ayer; David Schoenfeld,. Behavior Change, Health and Health Disparities 2013, Vermont Center on Behavior and Health, University of Vermont, Brown University, Burlington, VT. Extended Duration Pharmacotherapy for Sustained Tobacco Abstinence in People with Serious Mental Illness. 2013.
  27. Pachas GN, Cather C, Pratt SA, Hoeppner B, Nino J, Carlini SV, Achtyes ED, Lando H, Mueser KT, Rigotti NA, Goff DC, Evins AE. Varenicline for Smoking Cessation in Schizophrenia: Safety and Effectiveness in a 12-Week, Open-Label Trial. J Dual Diagn. 2012; 8(2):117-125. PMID: 22888309.
    Citations: 23     Fields:    
  28. Pachas GN, Nino J, Carlini S, Orr SP, Hoeppner B, Pittman RK, Evins AE. 18th Annual Meeting: Society for Research on Nicotine and Tobacco 2012. Effect of B-adrenergic Blockade on Physiologic and Affective Reactivity to Smoking Cues. 2012.
  29. Carlini SV, Pachas G, Fava M, Evins AE. 18th Annual Meeting: Society for Research on Nicotine and Tobacco 2012. Predictors of lapse after initial abstinence with nicotine replacement therapy in female smokers. 2012.
  30. Schuman-Olivier, Z, Hoeppner, Bettina, PhD; Pachas, Gladys N, MD; Evins, A. Eden, MD, . the international symposium of contemplative studies 2012 in Denver. MPH Feasibility and acceptability of actigraphy-based ecological momentary assessment for measurement of meditation practice and craving in a clinical trial of mindfulness training for smoking cessation. 2012.
  31. Evins AE, Pachas G, Mischoulon D, Urbanoski K, Carlini S, Sousa J, Bentley K, Rigotti NA, Nino-Gomez J, Loebl T, Janes AC, Kaufman MJ, Fava M. A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females. J Clin Psychopharmacol. 2011 Oct; 31(5):597-602. PMID: 21869693.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  32. Mashhoon Y, Janes AC, Jensen JE, Prescot AP, Pachas G, Renshaw PF, Fava M, Evins AE, Kaufman MJ. Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1709-13. PMID: 21616118.
    Citations: 13     Fields:    Translation:Humans
  33. Pachas GN, Carlini S, Milet R, Evins AE, Maravic MC. Eleventh Annual International Conference: National Hispanic Science Network on Drug Abuse, Pathways Toward Health Equities in Hispanic Populations. August 2011. The Integrated Dual Disorders Treatment (IDDT) Program, Proyecto Tranquilidad. 2011.
  34. Janes AC, Pizzagalli DA, Richardt S, deB Frederick B, Chuzi S, Pachas G, Culhane MA, Holmes AJ, Fava M, Evins AE, Kaufman MJ. Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biol Psychiatry. 2010 Apr 15; 67(8):722-9. PMID: 20172508.
    Citations: 208     Fields:    Translation:Humans
  35. Pachas GN, Carlini S, Nino-Gomez J, Pitman RK, Orr S, Evins AE. . 50th Anniversary Meeting: NCDEU 2010 New Investigator Award June 2010 and at the Massachusetts General Hospital Clinical Research Day May 2010, Departmental Award- Psychiatry. Effect of the B-adrenergic blocker propranolol on physiological responses to smoking cues using script-driven imagery. 2010.
  36. Yeterian J, Pachas G, Evins AE, Kelly J. . Handbook of Clinical Rating Scales Assessment in Psychiatry and Mental Health. Baer L, Blais MA, editors. Rating Scales for Alcohol and Nicotine Addiction. 2009.
  37. Janes AC, Pizzagalli DA, Richardt S, Frederick BB, Chuzi S, Pachas G, Culhane MA, Fava M, Evins AE, Kaufman MJ. Right Anterior Insula fMRI Smoking Cue Reactivity and the Emotional Stroop task Identify Smokers Who Will Slip During a Future Quit Attempt. 2009.
  38. Janes AC, Pizzagalli DA, Richardt S, Frederick BB, Chuzi S, Pachas G, Culhane MA, Fava M, Evins AE, Kaufman MJ. Harvard Medical School Department of Psychiatry Research Day: Mysell award. Insula reactivity to smoking-related cues and the emotional Stroop task predict slips in tobacco smoking abstinence. 2009.
  39. Pachas, Gladys N. The Psychiatry Report. Understanding Drug Addiction and Substance Abuse. 2008. View Publication.
  40. Dyer MA, Freudenreich O, Culhane MA, Pachas GN, Deckersbach T, Murphy E, Goff DC, Evins AE. High-dose galantamine augmentation inferior to placebo on attention, inhibitory control and working memory performance in nonsmokers with schizophrenia. Schizophr Res. 2008 Jul; 102(1-3):88-95. PMID: 18325740.
    Citations: 21     Fields:    Translation:Humans
  41. Loebl T, Angarita GA, Pachas GN, Huang KL, Lee SH, Nino J, Logvinenko T, Culhane MA, Evins AE. A randomized, double-blind, placebo-controlled trial of long-acting risperidone in cocaine-dependent men. J Clin Psychiatry. 2008 Mar; 69(3):480-6. PMID: 18294021.
    Citations: 13     Fields:    Translation:Humans
  42. Pizzagalli DA, Dillon DG, Evins AE, Holmes AJ, Birk J, Goetz E, Pachas G, Loebl T. the 63rd Annual Convention of the Society for Biological Psychiatry, May 1-3, 2008, Washington D.C., USA. Effects of a single dose of Bupropion on the neural substrates of reward processing in Major Depression: A double-blind, placebo-controlled fMRI study. 2008.
  43. Mashhoon Y, Janes AC, Jensen JE, Prescot AP, Pachas G, Renshaw PF, Fava M, Evins AE, Kaufman MJ. McLean Research Day, Belmont, Massachusetts, January 2011, Harvard Psychiatry Research Day. Boston, Massachusetts, March 2011 and at the College on Problems of Drug Dependence Annual Meeting. Hollywood, Florida, June 2011. Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.