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Peter Siekmeier, M.D.

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  1. K08MH072771 (SIEKMEIER, PETER J) Aug 21, 2007 - Apr 30, 2013
    NIH/NIMH
    Computational Modeling of Hippocampus in Schizophrenia
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Siekmeier PJ. An in Silico, Biomarker-Based Method for the Evaluation of Virtual Neuropsychiatric Drug Effects. Neural Comput. 2017 04; 29(4):1021-1052. PMID: 28181877.
    Citations:    Fields:    Translation:HumansCells
  2. Siekmeier, PJ. Systems and methods for modeling and predicting effective treatments for schizophrenia and other disorders. 2016.
  3. Siekmeier PJ. Computational modeling of psychiatric illnesses via well-defined neurophysiological and neurocognitive biomarkers. Neurosci Biobehav Rev. 2015 Oct; 57:365-80. PMID: 26432502.
    Citations: 2     Fields:    Translation:HumansAnimals
  4. Siekmeier, PJ, Stufflebeam, SM, Spencer, SK, Hamalainen, M, McCarley, R. Neuropsychopharmacology. Increased beta-gamma power ratio in MEG auditory steady-state responses: A potential biomarker for chronic schizophrenia. 2014; 39(S3):S627.
  5. Siekmeier PJ, vanMaanen DP. Dopaminergic contributions to hippocampal pathophysiology in schizophrenia: a computational study. Neuropsychopharmacology. 2014 Jun; 39(7):1713-21. PMID: 24469592.
    Citations: 1     Fields:    Translation:HumansAnimals
  6. Siekmeier, PJ, vanMaanen, DP. Neuropsychopharmacology. Treatment of dopaminergic dysfunction in schizophrenia using non-dopaminergic mechanisms: A computational modeling approach. 2013; 38(S2):S270.
  7. Siekmeier, PJ. Treating schizophrenia. 2013.
  8. Siekmeier PJ, vanMaanen DP. Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology. PLoS One. 2013; 8(3):e58607. PMID: 23526999.
    Citations: 7     Fields:    Translation:Humans
  9. Siekmeier, PJ, vanMaanen, DP. Neuropsychopharmacology. Computational modeling of hippocampus in schizophrenia and novel antipsychotic development. 2012; 38(S1):S187.
  10. Siekmeier, PJ, vanMaanen, D. Biological Psychiatry. Relating neuropathological findings in hippocampus to schizophrenic symptomatology: A computational modeling approach. 2012; 71(8S):312S.
  11. Siekmeier, PJ, Matthysse, SM. Methods and systems for drug screening and computational modeling based on biologically realistic neurons. 2011.
  12. Siekmeier PJ, Stufflebeam SM. Patterns of spontaneous magnetoencephalographic activity in patients with schizophrenia. J Clin Neurophysiol. 2010 Jun; 27(3):179-90. PMID: 20461010.
    Citations: 13     Fields:    Translation:Humans
  13. Siekmeier PJ. Evidence of multistability in a realistic computer simulation of hippocampus subfield CA1. Behav Brain Res. 2009 Jun 08; 200(1):220-31. PMID: 19378385.
    Citations: 4     Fields:    Translation:AnimalsCells
  14. Vierling-Claassen D, Siekmeier P, Stufflebeam S, Kopell N. Modeling GABA alterations in schizophrenia: a link between impaired inhibition and altered gamma and beta range auditory entrainment. J Neurophysiol. 2008 May; 99(5):2656-71. PMID: 18287555.
    Citations: 63     Fields:    Translation:HumansCells
  15. Siekmeier PJ, Hasselmo ME, Howard MW, Coyle J. Modeling of context-dependent retrieval in hippocampal region CA1: implications for cognitive function in schizophrenia. Schizophr Res. 2007 Jan; 89(1-3):177-90. PMID: 17055702.
    Citations: 14     Fields:    Translation:Humans
  16. Stufflebeam, S, Vierling-Claasen, D, Lin, F-H, Siekmeier, P, Hamalainen, M, Kopell, N, McCarley, R. New Frontiers in Biomagnetism: Proceedings of the 15th International Conference on Biomagnetism. Altered GABA receptor dynamics explains abnormal rhythmic auditory neuromagnetic response in schizophrenia. 2006.
  17. Siekmeier, PJ, Matthysse, SW. Methods and systems for neuropsyciatric drug screening and computational modeling. 2006.
  18. Siekmeier PJ, Hoffman RE. Enhanced semantic priming in schizophrenia: a computer model based on excessive pruning of local connections in association cortex. Br J Psychiatry. 2002 Apr; 180:345-50. PMID: 11925358.
    Citations: 11     Fields:    Translation:Humans
  19. Siekmeier, PJ. The Yale Journal of Biology and Medicine. The use of an attractor neural network model to explore normal brain function and the pathogenesis of schizophrenia. 1997; 3(70):275.
  20. Mori K, Ohya H, Matsumoto K, Furuune H, Isozaki K, Siekmeier P. Design for a bioreactor with sunlight supply and operations systems for use in the space environment. Adv Space Res. 1989; 9(8):161-8. PMID: 11537383.
    Citations:    Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.