Harvard Catalyst Profiles

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Chen Tan, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS116278 (TAN, CHEN SABRINA) Apr 15, 2020 - Jan 31, 2025
    NK cell responses to JC polyomavirus
    Role: Principal Investigator
  2. R33MH112360 (TAN, CHEN SABRINA) Sep 26, 2016 - Mar 31, 2022
    Antibody-based eradication of HIV from the CNS reservoirs
    Role: Principal Investigator
  3. R21MH112360 (TAN, CHEN SABRINA) Sep 26, 2016 - May 9, 2019
    Antibody-based eradication of HIV from the CNS reservoirs
    Role: Principal Investigator
  4. K02NS097146 (TAN, CHEN SABRINA) Sep 1, 2016 - May 31, 2022
    Characterization of broadly neutralizing antibodies against JC virus
    Role: Principal Investigator
  5. R21NS090951 (TAN, CHEN SABRINA) Apr 1, 2015 - Mar 31, 2019
    Mouse Model of Progressive Multifocal Leukoencephalopathy
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Stephenson KE, Le Gars M, Sadoff J, de Groot AM, Heerwegh D, Truyers C, Atyeo C, Loos C, Chandrashekar A, McMahan K, Tostanoski LH, Yu J, Gebre MS, Jacob-Dolan C, Li Z, Patel S, Peter L, Liu J, Borducchi EN, Nkolola JP, Souza M, Tan CS, Zash R, Julg B, Nathavitharana RR, Shapiro RL, Azim AA, Alonso CD, Jaegle K, Ansel JL, Kanjilal DG, Guiney CJ, Bradshaw C, Tyler A, Makoni T, Yanosick KE, Seaman MS, Lauffenburger DA, Alter G, Struyf F, Douoguih M, Van Hoof J, Schuitemaker H, Barouch DH. Immunogenicity of the Ad26.COV2.S Vaccine for COVID-19. JAMA. 2021 04 20; 325(15):1535-1544. PMID: 33704352; PMCID: PMC7953339.
    Citations: 97     Fields:    Translation:HumansCTClinical Trials
  2. Stephenson KE, Tan CS, Walsh SR, Hale A, Ansel JL, Kanjilal DG, Jaegle K, Peter L, Borducchi EN, Nkolola JP, Makoni T, Fogel R, Bradshaw C, Tyler A, Moseley E, Chandrashekar A, Yanosick KE, Seaman MS, Eckels KH, De La Barrera RA, Thompson J, Dawson P, Thomas SJ, Michael NL, Modjarrad K, Barouch DH. Safety and immunogenicity of a Zika purified inactivated virus vaccine given via standard, accelerated, or shortened schedules: a single-centre, double-blind, sequential-group, randomised, placebo-controlled, phase 1 trial. Lancet Infect Dis. 2020 09; 20(9):1061-1070. PMID: 32618279.
    Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
  3. Tan CS, Ghofrani J, Geiger E, Koralnik IJ, Jost S. Brief Report: Decreased JC Virus-Specific Antibody-Dependent Cellular Cytotoxicity in HIV-Seropositive PML Survivors. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):220-224. PMID: 31513076; PMCID: PMC7179760.
    Citations:    Fields:    Translation:HumansCells
  4. DeWolfe D, Aid M, McGann K, Ghofrani J, Geiger E, Helzer C, Malik S, Kleiboeker S, Jost S, Tan CS. NK Cells Contribute to the Immune Risk Profile in Kidney Transplant Candidates. Front Immunol. 2019; 10:1890. PMID: 31507586.
    Citations: 2     Fields:    Translation:HumansCells
  5. Karantanos T, Kim HT, Tijaro-Ovalle NM, Li L, Cutler C, Antin JH, Ballen K, Marty FM, Tan CS, Ritz J, Politikos I, Boussiotis V. Reactivation of BK virus after double umbilical cord blood transplantation in adults correlates with impaired reconstitution of CD4+ and CD8+ T effector memory cells and increase of T regulatory cells. Clin Immunol. 2019 10; 207:18-23. PMID: 31255803.
    Citations: 3     Fields:    Translation:HumansCells
  6. Tan CS, Gabardi S, Pavlakis M. Survey of BK virus screening practices by American society of transplantation members. Clin Transplant. 2019 07; 33(7):e13620. PMID: 31152561.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  7. Tan CS. Reactivation of Multiple Infectious Pathogens after Hematopoietic Stem Cell Transplantation. Acta Haematol. 2017; 138(1):1-2. PMID: 28595168.
    Citations:    Fields:    Translation:Humans
  8. DeWolfe D, Gandhi J, Mackenzie MR, Broge TA, Bord E, Babwah A, Mandelbrot DA, Pavlakis M, Cardarelli F, Viscidi R, Chandraker A, Tan CS. Pre-transplant immune factors may be associated with BK polyomavirus reactivation in kidney transplant recipients. PLoS One. 2017; 12(5):e0177339. PMID: 28562595.
    Citations: 3     Fields:    Translation:HumansCells
  9. Satyanarayana G, Hammond SP, Broge TA, Mackenzie MR, Viscidi R, Politikos I, Koralnik IJ, Cutler CS, Ballen K, Boussiotis V, Marty FM, Tan CS. BK polyomavirus reactivation after reduced-intensity double umbilical cord blood cell transplantation. Transpl Immunol. 2015 Mar; 32(2):116-20. PMID: 25536223; PMCID: PMC4368450.
    Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
  10. Tan CS, Broge TA, Ngo L, Gheuens S, Viscidi R, Bord E, Rosenblatt J, Wong M, Avigan D, Koralnik IJ. Immune reconstitution after allogeneic hematopoietic stem cell transplantation is associated with selective control of JC virus reactivation. Biol Blood Marrow Transplant. 2014 Jul; 20(7):992-9. PMID: 24680976.
    Citations: 9     Fields:    Translation:HumansCells
  11. Chalkias S, Mackenzie MR, Gay C, Dooley C, Marty FM, Moss RB, Li T, Routh RL, Walsh SR, Tan CS. DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation. Transpl Infect Dis. 2014 Feb; 16(1):141-4. PMID: 24383501.
    Citations: 24     Fields:    Translation:Humans
  12. Tan CS, Broge TA, Seung E, Vrbanac V, Viscidi R, Gordon J, Tager AM, Koralnik IJ. Detection of JC virus-specific immune responses in a novel humanized mouse model. PLoS One. 2013; 8(5):e64313. PMID: 23700470.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  13. Liu JJ, Toy WC, Wong MD, Tan CS, Tavintharan S, Wong MS, Sum CF, Lim SC. Elevated undercarboxylated and reduced carboxylated osteocalcin are associated with metabolic syndrome in middle age Asian females. Exp Clin Endocrinol Diabetes. 2013 Jun; 121(6):329-33. PMID: 23512417.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  14. Tan CS, Bord E, Broge TA, Glotzbecker B, Mills H, Gheuens S, Rosenblatt J, Avigan D, Koralnik IJ. Increased program cell death-1 expression on T lymphocytes of patients with progressive multifocal leukoencephalopathy. J Acquir Immune Defic Syndr. 2012 Jul 01; 60(3):244-8. PMID: 22549384; PMCID: PMC3400136.
    Citations: 30     Fields:    Translation:HumansCells
  15. Viscidi RP, Khanna N, Tan CS, Li X, Jacobson L, Clifford DB, Nath A, Margolick JB, Shah KV, Hirsch HH, Koralnik IJ. JC virus antibody and viremia as predictors of progressive multifocal leukoencephalopathy in human immunodeficiency virus-1-infected individuals. Clin Infect Dis. 2011 Oct; 53(7):711-5. PMID: 21852452.
    Citations: 20     Fields:    Translation:HumansCells
  16. Dang X, Bialasiewicz S, Nissen MD, Sloots TP, Koralnik IJ, Tan CS. Infrequent detection of KI, WU and MC polyomaviruses in immunosuppressed individuals with or without progressive multifocal leukoencephalopathy. PLoS One. 2011 Mar 16; 6(3):e16736. PMID: 21436884; PMCID: PMC3059210.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  17. Tan CS, Ellis LC, Wüthrich C, Ngo L, Broge TA, Saint-Aubyn J, Miller JS, Koralnik IJ. JC virus latency in the brain and extraneural organs of patients with and without progressive multifocal leukoencephalopathy. J Virol. 2010 Sep; 84(18):9200-9. PMID: 20610709.
    Citations: 41     Fields:    Translation:HumansCells
  18. Tan CS, Chen Y, Viscidi RP, Kinkel RP, Stein MC, Koralnik IJ. Discrepant findings in immune responses to JC virus in patients receiving natalizumab. Lancet Neurol. 2010 Jun; 9(6):565-6; author reply 566-7. PMID: 20494320.
    Citations: 5     Fields:    Translation:HumansCells
  19. Tan CS, Koralnik IJ. Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis. Lancet Neurol. 2010 Apr; 9(4):425-37. PMID: 20298966.
    Citations: 243     Fields:    Translation:HumansCells
  20. Chen Y, Bord E, Tompkins T, Miller J, Tan CS, Kinkel RP, Stein MC, Viscidi RP, Ngo LH, Koralnik IJ. Asymptomatic reactivation of JC virus in patients treated with natalizumab. N Engl J Med. 2009 Sep 10; 361(11):1067-74. PMID: 19741227; PMCID: PMC3077718.
    Citations: 90     Fields:    Translation:HumansCellsCTClinical Trials
  21. Tan CS, Dezube BJ, Bhargava P, Autissier P, Wüthrich C, Miller J, Koralnik IJ. Detection of JC virus DNA and proteins in the bone marrow of HIV-positive and HIV-negative patients: implications for viral latency and neurotropic transformation. J Infect Dis. 2009 Mar 15; 199(6):881-8. PMID: 19434914; PMCID: PMC2893283.
    Citations: 52     Fields:    Translation:HumansCells
  22. Marzocchetti A, Wuthrich C, Tan CS, Tompkins T, Bernal-Cano F, Bhargava P, Ropper AH, Koralnik IJ. Rearrangement of the JC virus regulatory region sequence in the bone marrow of a patient with rheumatoid arthritis and progressive multifocal leukoencephalopathy. J Neurovirol. 2008 Oct; 14(5):455-8. PMID: 18989816; PMCID: PMC2643300.
    Citations: 26     Fields:    Translation:HumansCells
  23. Rosmarin D, Tan CS. Images in clinical medicine. Inguinal hernia. N Engl J Med. 2006 Aug 10; 355(6):601. PMID: 16899780.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.