Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Sapna Syngal, M.D.

Title
Institution
Department
Address
Phone
Fax

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA132829 (SYNGAL, SAPNA) Apr 1, 2008 - Jan 31, 2023
    NIH/NCI
    Development and validation of clinical prediction models for the use and interpretation of multigene hereditary cancer risk assessment
    Role: Principal Investigator
  2. K24CA113433 (SYNGAL, SAPNA) Aug 1, 2005 - Jul 31, 2015
    NIH/NCI
    The Genetics and Prevention of Gastrointestinal Cancers
    Role: Principal Investigator
  3. R01CA085759 (SYNGAL, SAPNA) Apr 1, 2001 - Mar 31, 2008
    NIH/NCI
    INHERITED MSH6 MUTATIONS IN DIVERSE COLORECTAL CANCERS
    Role: Principal Investigator
  4. K07CA085453 (SYNGAL, SAPNA) Sep 30, 2000 - Sep 29, 2005
    NIH/NCI
    CANCER SCREENING COMPLIANCE IN HEREDITARY COLON CANCER
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Biller LH, Syngal S, Yurgelun MB. Recent advances in Lynch syndrome. Fam Cancer. 2019 04; 18(2):211-219. PMID: 30627969.
    Citations:    Fields:    
  2. Clarke EV, Muessig KR, Zepp J, Hunter JE, Syngal S, Acheson LS, Wiesner GL, Peterson SK, Bergen KM, Shuster E, Davis JV, Schneider JL, Kauffman TL, Gilmore MJ, Reiss JA, Rope AF, Cook JE, Goddard KAB. Implementation of a Systematic Tumor Screening Program for Lynch Syndrome in an Integrated Health Care Setting. Fam Cancer. 2019 Feb 07. PMID: 30729418.
    Citations:    
  3. Goggins MG, Lippman SM, Constantinou PE, Jacks T, Petersen GM, Syngal S, Maitra A. Intercepting Pancreatic Cancer: Our Dream Team's Resolve to Stop Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1175-1176. PMID: 30325853.
    Citations:    Fields:    
  4. Kastrinos F, Uno H, Syngal S. Commentary: PREMM5 threshold of 2.5% is recommended to improve identification of PMS2 carriers. Fam Cancer. 2018 10; 17(4):567. PMID: 29380099.
    Citations:    Fields:    Translation:Humans
  5. Yurgelun MB, Chittenden AB, Morales-Oyarvide V, Rubinson DA, Dunne RF, Kozak MM, Qian ZR, Welch MW, Brais LK, Da Silva A, Bui JL, Yuan C, Li T, Li W, Masuda A, Gu M, Bullock AJ, Chang DT, Clancy TE, Linehan DC, Findeis-Hosey JJ, Doyle LA, Thorner AR, Ducar MD, Wollison BM, Khalaf N, Perez K, Syngal S, Aguirre AJ, Hahn WC, Meyerson ML, Fuchs CS, Ogino S, Hornick JL, Hezel AF, Koong AC, Nowak JA, Wolpin BM. Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer. Genet Med. 2019 01; 21(1):213-223. PMID: 29961768.
    Citations: 1     Fields:    
  6. Syngal S, Furniss CS. Germline Genetic Testing for Pancreatic Ductal Adenocarcinoma at Time of Diagnosis. JAMA. 2018 06 19; 319(23):2383-2385. PMID: 29922810.
    Citations:    Fields:    Translation:Humans
  7. Rebbeck TR, Burns-White K, Chan AT, Emmons K, Freedman M, Hunter DJ, Kraft P, Laden F, Mucci L, Parmigiani G, Schrag D, Syngal S, Tamimi RM, Viswanath K, Yurgelun MB, Garber JE. Precision Prevention and Early Detection of Cancer: Fundamental Principles. Cancer Discov. 2018 Jul; 8(7):803-811. PMID: 29907587.
    Citations:    Fields:    
  8. Schneider JL, Goddard KAB, Muessig KR, Davis JV, Rope AF, Hunter JE, Peterson SK, Acheson LS, Syngal S, Wiesner GL, Reiss JA. Patient and provider perspectives on adherence to and care coordination of lynch syndrome surveillance recommendations: findings from qualitative interviews. Hered Cancer Clin Pract. 2018; 16:11. PMID: 29760830.
    Citations:    
  9. Underhill M, Hong F, Lawrence J, Blonquist T, Syngal S. Relationship between individual and family characteristics and psychosocial factors in persons with familial pancreatic cancer. Psychooncology. 2018 07; 27(7):1711-1718. PMID: 29570238.
    Citations:    Fields:    
  10. Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, MacGregor-Das A, Borges M, Wolfgang CL, Weiss MJ, He J, Canto MI, Petersen GM, Gallinger S, Syngal S, Brand RE, Rustgi A, Olson SH, Stoffel E, Cote ML, Zogopoulos G, Potash JB, Goes FS, McCombie RW, Zandi PP, Pirooznia M, Kramer M, Parla J, Eshleman JR, Roberts NJ, Hruban RH, Klein AP, Goggins M. Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. Proc Natl Acad Sci U S A. 2018 05 01; 115(18):4767-4772. PMID: 29669919.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  11. AlDubayan SH, Giannakis M, Moore ND, Han GC, Reardon B, Hamada T, Mu XJ, Nishihara R, Qian Z, Liu L, Yurgelun MB, Syngal S, Garraway LA, Ogino S, Fuchs CS, Van Allen EM. Inherited DNA-Repair Defects in Colorectal Cancer. Am J Hum Genet. 2018 03 01; 102(3):401-414. PMID: 29478780.
    Citations:    Fields:    Translation:HumansCells
  12. Steyerberg EW, Uno H, Ioannidis JPA, van Calster B. Poor performance of clinical prediction models: the harm of commonly applied methods. J Clin Epidemiol. 2018 Jun; 98:133-143. PMID: 29174118.
    Citations:    Fields:    
  13. Hunter JE, Arnold KA, Cook JE, Zepp J, Gilmore MJ, Rope AF, Davis JV, Bergen KM, Esterberg E, Muessig KR, Peterson SK, Syngal S, Acheson L, Wiesner G, Reiss J, Goddard KAB. Universal screening for Lynch syndrome among patients with colorectal cancer: patient perspectives on screening and sharing results with at-risk relatives. Fam Cancer. 2017 07; 16(3):377-387. PMID: 28176204.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  14. Luba DG, DiSario JA, Rock C, Saraiya D, Moyes K, Brown K, Rushton K, Ogara MM, Raphael M, Zimmerman D, Garrido K, Silguero E, Nelson J, Yurgelun MB, Kastrinos F, Wenstrup RJ, Syngal S. Community Practice Implementation of a Self-administered Version of PREMM1,2,6 to Assess Risk for Lynch Syndrome. Clin Gastroenterol Hepatol. 2018 Jan; 16(1):49-58. PMID: 28668538.
    Citations:    Fields:    Translation:Humans
  15. Yurgelun MB, Syngal S. Reply to M.S. Daniels et al. J Clin Oncol. 2017 08 01; 35(22):2588-2589. PMID: 28510494.
    Citations:    Fields:    
  16. Kastrinos F, Uno H, Ukaegbu C, Alvero C, McFarland A, Yurgelun MB, Kulke MH, Schrag D, Meyerhardt JA, Fuchs CS, Mayer RJ, Ng K, Steyerberg EW, Syngal S. Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome. J Clin Oncol. 2017 Jul 01; 35(19):2165-2172. PMID: 28489507.
    Citations: 6     Fields:    Translation:Humans
  17. Q Rana H, Syngal S. Biallelic Mismatch Repair Deficiency: Management and Prevention of a Devastating Manifestation of the Lynch Syndrome. Gastroenterology. 2017 05; 152(6):1254-1257. PMID: 28327367.
    Citations:    Fields:    Translation:HumansCells
  18. Watkins JC, Yang EJ, Muto MG, Feltmate CM, Berkowitz RS, Horowitz NS, Syngal S, Yurgelun MB, Chittenden A, Hornick JL, Crum CP, Sholl LM, Howitt BE. Universal Screening for Mismatch-Repair Deficiency in Endometrial Cancers to Identify Patients With Lynch Syndrome and Lynch-like Syndrome. Int J Gynecol Pathol. 2017 Mar; 36(2):115-127. PMID: 27556954.
    Citations: 5     Fields:    Translation:HumansCells
  19. Yurgelun MB, Kulke MH, Fuchs CS, Allen BA, Uno H, Hornick JL, Ukaegbu CI, Brais LK, McNamara PG, Mayer RJ, Schrag D, Meyerhardt JA, Ng K, Kidd J, Singh N, Hartman AR, Wenstrup RJ, Syngal S. Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. J Clin Oncol. 2017 Apr 01; 35(10):1086-1095. PMID: 28135145.
    Citations: 15     Fields:    Translation:Humans
  20. Inra JA, Nayor J, Rosenblatt M, Mutinga M, Reddy SI, Syngal S, Kastrinos F. Comparison of Colonoscopy Quality Measures Across Various Practice Settings and the Impact of Performance Scorecards. Dig Dis Sci. 2017 04; 62(4):894-902. PMID: 27995405.
    Citations: 4     Fields:    Translation:Humans
  21. Lowery JT, Ahnen DJ, Schroy PC, Hampel H, Baxter N, Boland CR, Burt RW, Butterly L, Doerr M, Doroshenk M, Feero WG, Henrikson N, Ladabaum U, Lieberman D, McFarland EG, Peterson SK, Raymond M, Samadder NJ, Syngal S, Weber TK, Zauber AG, Smith R. Understanding the contribution of family history to colorectal cancer risk and its clinical implications: A state-of-the-science review. Cancer. 2016 09 01; 122(17):2633-45. PMID: 27258162.
    Citations: 10     Fields:    Translation:Humans
  22. Xicola RM, Bontu S, Doyle BJ, Rawson J, Garre P, Lee E, de la Hoya M, Bessa X, Clofent J, Bujanda L, Balaguer F, Castellví-Bel S, Alenda C, Jover R, Ruiz-Ponte C, Syngal S, Andreu M, Carracedo A, Castells A, Newcomb PA, Lindor N, Potter JD, Baron JA, Ellis NA, Caldes T, LLor X. Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC). Carcinogenesis. 2016 08; 37(8):751-8. PMID: 27234654.
    Citations: 3     Fields:    Translation:HumansCells
  23. Childs EJ, Chaffee KG, Gallinger S, Syngal S, Schwartz AG, Cote ML, Bondy ML, Hruban RH, Chanock SJ, Hoover RN, Fuchs CS, Rider DN, Amundadottir LT, Stolzenberg-Solomon R, Wolpin BM, Risch HA, Goggins MG, Petersen GM, Klein AP. Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study. Cancer Epidemiol Biomarkers Prev. 2016 07; 25(7):1185-91. PMID: 27197284.
    Citations: 4     Fields:    Translation:HumansCells
  24. Parikh AR, Keating NL, Liu PH, Gray SW, Klabunde CN, Kahn KL, Haggstrom DA, Syngal S, Kim B. Oncologists' Selection of Genetic and Molecular Testing in the Evolving Landscape of Stage II Colorectal Cancer. J Oncol Pract. 2016 Mar; 12(3):e308-19, 259-60. PMID: 26962170.
    Citations:    Fields:    Translation:Humans
  25. Grover S, Lim RM, Blumberg RS, Syngal S. Oncogastroenterology. J Clin Oncol. 2016 Apr 01; 34(10):1154-5. PMID: 26834060.
    Citations:    Fields:    Translation:Humans
  26. Lynch PM, Morris JS, Wen S, Advani SM, Ross W, Chang GJ, Rodriguez-Bigas M, Raju GS, Ricciardiello L, Iwama T, Rossi BM, Pellise M, Stoffel E, Wise PE, Bertario L, Saunders B, Burt R, Belluzzi A, Ahnen D, Matsubara N, Bülow S, Jespersen N, Clark SK, Erdman SH, Markowitz AJ, Bernstein I, De Haas N, Syngal S, Moeslein G. A proposed staging system and stage-specific interventions for familial adenomatous polyposis. Gastrointest Endosc. 2016 Jul; 84(1):115-125.e4. PMID: 26769407.
    Citations: 3     Fields:    Translation:Humans
  27. Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel E, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, Chaffee KG, Chen YC, Cote ML, Childs EJ, Douville C, Goes FS, Herman JM, Iacobuzio-Donahue C, Kramer M, Makohon-Moore A, McCombie RW, McMahon KW, Niknafs N, Parla J, Pirooznia M, Potash JB, Rhim AD, Smith AL, Wang Y, Wolfgang CL, Wood LD, Zandi PP, Goggins M, Karchin R, Eshleman JR, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH, Klein AP. Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer. Cancer Discov. 2016 Feb; 6(2):166-75. PMID: 26658419.
    Citations: 33     Fields:    Translation:Humans
  28. Kastrinos F, Ojha RP, Leenen C, Alvero C, Mercado RC, Balmaña J, Valenzuela I, Balaguer F, Green R, Lindor NM, Thibodeau SN, Newcomb P, Win AK, Jenkins M, Buchanan DD, Bertario L, Sala P, Hampel H, Syngal S, Steyerberg EW. Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer. J Natl Cancer Inst. 2016 Feb; 108(2). PMID: 26582061.
    Citations: 9     Fields:    Translation:Humans
  29. Robson ME, Bradbury AR, Arun B, Domchek SM, Ford JM, Hampel HL, Lipkin SM, Syngal S, Wollins DS, Lindor NM. American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility. J Clin Oncol. 2015 Nov 01; 33(31):3660-7. PMID: 26324357.
    Citations: 50     Fields:    Translation:Humans
  30. Hunter JE, Zepp JM, Gilmore MJ, Davis JV, Esterberg EJ, Muessig KR, Peterson SK, Syngal S, Acheson LS, Wiesner GL, Reiss JA, Goddard KA. Universal tumor screening for Lynch syndrome: Assessment of the perspectives of patients with colorectal cancer regarding benefits and barriers. Cancer. 2015 Sep 15; 121(18):3281-9. PMID: 26036338.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  31. Underhill M, Berry D, Dalton E, Schienda J, Syngal S. Patient experiences living with pancreatic cancer risk. Hered Cancer Clin Pract. 2015; 13(1):13. PMID: 26029287.
    Citations: 2     
  32. Yurgelun MB, Allen B, Kaldate RR, Bowles KR, Judkins T, Kaushik P, Roa BB, Wenstrup RJ, Hartman AR, Syngal S. Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. Gastroenterology. 2015 Sep; 149(3):604-13.e20. PMID: 25980754.
    Citations: 29     Fields:    Translation:Humans
  33. Yurgelun MB, Masciari S, Joshi VA, Mercado RC, Lindor NM, Gallinger S, Hopper JL, Jenkins MA, Buchanan DD, Newcomb PA, Potter JD, Haile RW, Kucherlapati R, Syngal S. Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry. JAMA Oncol. 2015 May; 1(2):214-21. PMID: 26086041.
    Citations: 13     Fields:    Translation:HumansCells
  34. Shin EJ, Topazian M, Goggins MG, Syngal S, Saltzman JR, Lee JH, Farrell JJ, Canto MI. Linear-array EUS improves detection of pancreatic lesions in high-risk individuals: a randomized tandem study. Gastrointest Endosc. 2015 Nov; 82(5):812-8. PMID: 25930097.
    Citations: 5     Fields:    Translation:Humans
  35. Schneider JL, Davis J, Kauffman TL, Reiss JA, McGinley C, Arnold K, Zepp J, Gilmore M, Muessig KR, Syngal S, Acheson L, Wiesner GL, Peterson SK, Goddard KA. Stakeholder perspectives on implementing a universal Lynch syndrome screening program: a qualitative study of early barriers and facilitators. Genet Med. 2016 Feb; 18(2):152-61. PMID: 25880440.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  36. Goodenberger ML, Thomas BC, Riegert-Johnson D, Boland CR, Plon SE, Clendenning M, Win AK, Senter L, Lipkin SM, Stadler ZK, Macrae FA, Lynch HT, Weitzel JN, de la Chapelle A, Syngal S, Lynch P, Parry S, Jenkins MA, Gallinger S, Holter S, Aronson M, Newcomb PA, Burnett T, Le Marchand L, Pichurin P, Hampel H, Terdiman JP, Lu KH, Thibodeau S, Lindor NM. PMS2 monoallelic mutation carriers: the known unknown. Genet Med. 2016 Jan; 18(1):13-9. PMID: 25856668.
    Citations: 9     Fields:    Translation:Humans
  37. Syngal S, Brand RE, Church JM, Giardiello FM, Hampel HL, Burt RW. ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol. 2015 Feb; 110(2):223-62; quiz 263. PMID: 25645574.
    Citations: 123     Fields:    Translation:Humans
  38. Inra JA, Steyerberg EW, Grover S, McFarland A, Syngal S, Kastrinos F. Racial variation in frequency and phenotypes of APC and MUTYH mutations in 6,169 individuals undergoing genetic testing. Genet Med. 2015 Oct; 17(10):815-21. PMID: 25590978.
    Citations: 5     Fields:    Translation:Humans
  39. Rastegar N, Matteoni-Athayde LG, Eng J, Takahashi N, Tamm EP, Mortele KJ, Syngal S, Margolis D, Lennon AM, Wolfgang CL, Fishman EK, Hruban RH, Goggins M, Canto MI, Kamel IR. Incremental value of secretin-enhanced magnetic resonance cholangiopancreatography in detecting ductal communication in a population with high prevalence of small pancreatic cysts. Eur J Radiol. 2015 Apr; 84(4):575-80. PMID: 25619503.
    Citations: 8     Fields:    Translation:Humans
  40. Inra JA, Syngal S. Colorectal cancer in young adults. Dig Dis Sci. 2015 Mar; 60(3):722-33. PMID: 25480403.
    Citations: 21     Fields:    Translation:HumansPHPublic Health
  41. Eshleman JR, Norris AL, Sadakari Y, Debeljak M, Borges M, Harrington C, Lin E, Brant A, Barkley T, Almario JA, Topazian M, Farrell J, Syngal S, Lee JH, Yu J, Hruban RH, Kanda M, Canto MI, Goggins M. KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound. Clin Gastroenterol Hepatol. 2015 May; 13(5):963-9.e4. PMID: 25481712.
    Citations: 17     Fields:    Translation:Humans
  42. Everett JN, Raymond VM, Dandapani M, Marvin M, Kohlmann W, Chittenden A, Koeppe E, Gustafson SL, Else T, Fullen DR, Johnson TM, Syngal S, Gruber SB, Stoffel EM. Screening for germline mismatch repair mutations following diagnosis of sebaceous neoplasm. JAMA Dermatol. 2014 Dec; 150(12):1315-21. PMID: 25006859.
    Citations: 5     Fields:    Translation:HumansCells
  43. Zhen DB, Rabe KG, Gallinger S, Syngal S, Schwartz AG, Goggins MG, Hruban RH, Cote ML, McWilliams RR, Roberts NJ, Cannon-Albright LA, Li D, Moyes K, Wenstrup RJ, Hartman AR, Seminara D, Klein AP, Petersen GM. BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study. Genet Med. 2015 Jul; 17(7):569-77. PMID: 25356972.
    Citations: 28     Fields:    Translation:Humans
  44. Greaney ML, Puleo E, Sprunck-Harrild K, Syngal S, Suarez EG, Emmons KM. Changes in colorectal cancer screening intention among people aged 18-49 in the United States. BMC Public Health. 2014 Sep 01; 14:901. PMID: 25179871.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  45. Giardiello FM, Allen JI, Axilbund JE, Boland CR, Burke CA, Burt RW, Church JM, Dominitz JA, Johnson DA, Kaltenbach T, Levin TR, Lieberman DA, Robertson DJ, Syngal S, Rex DK. Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer. Dis Colon Rectum. 2014 Aug; 57(8):1025-48. PMID: 25003300.
    Citations: 12     Fields:    Translation:Humans
  46. Giardiello FM, Allen JI, Axilbund JE, Boland CR, Burke CA, Burt RW, Church JM, Dominitz JA, Johnson DA, Kaltenbach T, Levin TR, Lieberman DA, Robertson DJ, Syngal S, Rex DK. Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the U.S. Multi-Society Task Force on Colorectal Cancer. Gastrointest Endosc. 2014 Aug; 80(2):197-220. PMID: 25034835.
    Citations: 7     Fields:    Translation:Humans
  47. Giardiello FM, Allen JI, Axilbund JE, Boland CR, Burke CA, Burt RW, Church JM, Dominitz JA, Johnson DA, Kaltenbach T, Levin TR, Lieberman DA, Robertson DJ, Syngal S, Rex DK. Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on colorectal cancer. Gastroenterology. 2014 Aug; 147(2):502-26. PMID: 25043945.
    Citations: 53     Fields:    Translation:Humans
  48. Giardiello FM, Allen JI, Axilbund JE, Boland CR, Burke CA, Burt RW, Church JM, Dominitz JA, Johnson DA, Kaltenbach T, Levin TR, Lieberman DA, Robertson DJ, Syngal S, Rex DK. Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-society Task Force on colorectal cancer. Am J Gastroenterol. 2014 Aug; 109(8):1159-79. PMID: 25070057.
    Citations: 63     Fields:    Translation:Humans
  49. Ma T, Jang EJ, Zukerberg LR, Odze R, Gala MK, Kelsey PB, Forcione DG, Brugge WR, Casey BW, Syngal S, Chung DC. Recurrences are common after endoscopic ampullectomy for adenoma in the familial adenomatous polyposis (FAP) syndrome. Surg Endosc. 2014 Aug; 28(8):2349-56. PMID: 24566750.
    Citations: 4     Fields:    Translation:Humans
  50. Lu KH, Wood ME, Daniels M, Burke C, Ford J, Kauff ND, Kohlmann W, Lindor NM, Mulvey TM, Robinson L, Rubinstein WS, Stoffel EM, Snyder C, Syngal S, Merrill JK, Wollins DS, Hughes KS. American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. J Clin Oncol. 2014 Mar 10; 32(8):833-40. PMID: 24493721.
    Citations: 33     Fields:    Translation:Humans
  51. Yurgelun MB, Hornick JL, Curry VK, Ukaegbu CI, Brown EK, Hiller E, Chittenden A, Goldberg JE, Syngal S. Therapy-associated polyposis as a late sequela of cancer treatment. Clin Gastroenterol Hepatol. 2014 Jun; 12(6):1046-50. PMID: 24362051.
    Citations: 1     Fields:    Translation:Humans
  52. Perencevich M, Ojha RP, Steyerberg EW, Syngal S. Racial and ethnic variations in the effects of family history of colorectal cancer on screening compliance. Gastroenterology. 2013 Oct; 145(4):775-81.e2. PMID: 23796457.
    Citations: 8     Fields:    Translation:Humans
  53. Kastrinos F, Balmaña J, Syngal S. Prediction models in Lynch syndrome. Fam Cancer. 2013 Jun; 12(2):217-28. PMID: 23553450.
    Citations: 6     Fields:    Translation:Humans
  54. Raymond VM, Mukherjee B, Wang F, Huang SC, Stoffel EM, Kastrinos F, Syngal S, Cooney KA, Gruber SB. Elevated risk of prostate cancer among men with Lynch syndrome. J Clin Oncol. 2013 May 10; 31(14):1713-8. PMID: 23530095.
    Citations: 27     Fields:    Translation:HumansCells
  55. Kanda M, Sadakari Y, Borges M, Topazian M, Farrell J, Syngal S, Lee J, Kamel I, Lennon AM, Knight S, Fujiwara S, Hruban RH, Canto MI, Goggins M. Mutant TP53 in duodenal samples of pancreatic juice from patients with pancreatic cancer or high-grade dysplasia. Clin Gastroenterol Hepatol. 2013 Jun; 11(6):719-30.e5. PMID: 23200980.
    Citations: 44     Fields:    Translation:Humans
  56. Yurgelun MB, Mercado R, Rosenblatt M, Dandapani M, Kohlmann W, Conrad P, Blanco A, Shannon KM, Chung DC, Terdiman J, Gruber SB, Garber JE, Syngal S, Stoffel EM. Impact of genetic testing on endometrial cancer risk-reducing practices in women at risk for Lynch syndrome. Gynecol Oncol. 2012 Dec; 127(3):544-51. PMID: 22940489.
    Citations: 9     Fields:    Translation:HumansCells
  57. Kanda M, Knight S, Topazian M, Syngal S, Farrell J, Lee J, Kamel I, Lennon AM, Borges M, Young A, Fujiwara S, Seike J, Eshleman J, Hruban RH, Canto MI, Goggins M. Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts. Gut. 2013 Jul; 62(7):1024-33. PMID: 22859495.
    Citations: 55     Fields:    Translation:Humans
  58. Grover S, Kastrinos F, Steyerberg EW, Cook EF, Dewanwala A, Burbidge LA, Wenstrup RJ, Syngal S. Prevalence and phenotypes of APC and MUTYH mutations in patients with multiple colorectal adenomas. JAMA. 2012 Aug 01; 308(5):485-492. PMID: 22851115.
    Citations: 29     Fields:    Translation:Humans
  59. Al-Sukhni W, Joe S, Lionel AC, Zwingerman N, Zogopoulos G, Marshall CR, Borgida A, Holter S, Gropper A, Moore S, Bondy M, Klein AP, Petersen GM, Rabe KG, Schwartz AG, Syngal S, Scherer SW, Gallinger S. Identification of germline genomic copy number variation in familial pancreatic cancer. Hum Genet. 2012 Sep; 131(9):1481-94. PMID: 22665139.
    Citations: 11     Fields:    Translation:HumansCells
  60. Thompson JS, Lebwohl B, Syngal S, Kastrinos F. Knowledge of quality performance measures associated with endoscopy among gastroenterology trainees and the impact of a web-based intervention. Gastrointest Endosc. 2012 Jul; 76(1):100-6.e1-4. PMID: 22421498.
    Citations: 6     Fields:    Translation:Humans
  61. Mercado RC, Hampel H, Kastrinos F, Steyerberg E, Balmana J, Stoffel E, Cohn DE, Backes FJ, Hopper JL, Jenkins MA, Lindor NM, Casey G, Haile R, Madhavan S, de la Chapelle A, Syngal S. Performance of PREMM(1,2,6), MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases. Genet Med. 2012 Jul; 14(7):670-80. PMID: 22402756.
    Citations: 14     Fields:    Translation:Humans
  62. Kastrinos F, Syngal S. Screening patients with colorectal cancer for Lynch syndrome: what are we waiting for? J Clin Oncol. 2012 Apr 01; 30(10):1024-7. PMID: 22355054.
    Citations: 11     Fields:    Translation:Humans
  63. Kastrinos F, Steyerberg EW, Balmaña J, Mercado R, Gallinger S, Haile R, Casey G, Hopper JL, LeMarchand L, Lindor NM, Newcomb PA, Thibodeau SN, Syngal S. Comparison of the clinical prediction model PREMM(1,2,6) and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer. Gut. 2013 Feb; 62(2):272-9. PMID: 22345660.
    Citations: 16     Fields:    Translation:HumansCells
  64. Yurgelun MB, Goel A, Hornick JL, Sen A, Turgeon DK, Ruffin MT, Marcon NE, Baron JA, Bresalier RS, Syngal S, Brenner DE, Boland CR, Stoffel EM. Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps. Cancer Prev Res (Phila). 2012 Apr; 5(4):574-82. PMID: 22262812.
    Citations: 20     Fields:    Translation:HumansCells
  65. Canto MI, Hruban RH, Fishman EK, Kamel IR, Schulick R, Zhang Z, Topazian M, Takahashi N, Fletcher J, Petersen G, Klein AP, Axilbund J, Griffin C, Syngal S, Saltzman JR, Mortele KJ, Lee J, Tamm E, Vikram R, Bhosale P, Margolis D, Farrell J, Goggins M. Frequent detection of pancreatic lesions in asymptomatic high-risk individuals. Gastroenterology. 2012 Apr; 142(4):796-804; quiz e14-5. PMID: 22245846.
    Citations: 141     Fields:    Translation:Humans
  66. Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy ML, Gallinger S, Schwartz AG, Syngal S, Cote ML, Axilbund J, Schulick R, Ali SZ, Eshleman JR, Velculescu VE, Goggins M, Vogelstein B, Papadopoulos N, Hruban RH, Kinzler KW, Klein AP. ATM mutations in patients with hereditary pancreatic cancer. Cancer Discov. 2012 Jan; 2(1):41-6. PMID: 22585167.
    Citations: 117     Fields:    Translation:Humans
  67. Kastrinos F, Syngal S. Inherited colorectal cancer syndromes. Cancer J. 2011 Nov-Dec; 17(6):405-15. PMID: 22157284.
    Citations: 27     Fields:    Translation:Humans
  68. Dewanwala A, Chittenden A, Rosenblatt M, Mercado R, Garber JE, Syngal S, Stoffel EM. Attitudes toward childbearing and prenatal testing in individuals undergoing genetic testing for Lynch syndrome. Fam Cancer. 2011 Sep; 10(3):549-56. PMID: 21567236.
    Citations: 6     Fields:    Translation:HumansCells
  69. Tomsic J, Liyanarachchi S, Hampel H, Morak M, Thomas BC, Raymond VM, Chittenden A, Schackert HK, Gruber SB, Syngal S, Viel A, Holinski-Feder E, Thibodeau SN, de la Chapelle A. An American founder mutation in MLH1. Int J Cancer. 2012 May 01; 130(9):2088-95. PMID: 21671475.
    Citations: 4     Fields:    Translation:HumansCells
  70. Balaguer F, Moreira L, Lozano JJ, Link A, Ramirez G, Shen Y, Cuatrecasas M, Arnold M, Meltzer SJ, Syngal S, Stoffel E, Jover R, Llor X, Castells A, Boland CR, Gironella M, Goel A. Colorectal cancers with microsatellite instability display unique miRNA profiles. Clin Cancer Res. 2011 Oct 01; 17(19):6239-49. PMID: 21844009.
    Citations: 34     Fields:    Translation:Humans
  71. Masciari S, Dewanwala A, Stoffel EM, Lauwers GY, Zheng H, Achatz MI, Riegert-Johnson D, Foretova L, Silva EM, Digianni L, Verselis SJ, Schneider K, Li FP, Fraumeni J, Garber JE, Syngal S. Gastric cancer in individuals with Li-Fraumeni syndrome. Genet Med. 2011 Jul; 13(7):651-7. PMID: 21552135.
    Citations: 22     Fields:    Translation:Humans
  72. Levy DE, Byfield SD, Comstock CB, Garber JE, Syngal S, Crown WH, Shields AE. Underutilization of BRCA1/2 testing to guide breast cancer treatment: black and Hispanic women particularly at risk. Genet Med. 2011 Apr; 13(4):349-55. PMID: 21358336.
    Citations: 54     Fields:    Translation:Humans
  73. Kuiper RP, Vissers LE, Venkatachalam R, Bodmer D, Hoenselaar E, Goossens M, Haufe A, Kamping E, Niessen RC, Hogervorst FB, Gille JJ, Redeker B, Tops CM, van Gijn ME, van den Ouweland AM, Rahner N, Steinke V, Kahl P, Holinski-Feder E, Morak M, Kloor M, Stemmler S, Betz B, Hutter P, Bunyan DJ, Syngal S, Culver JO, Graham T, Chan TL, Nagtegaal ID, van Krieken JH, Schackert HK, Hoogerbrugge N, van Kessel AG, Ligtenberg MJ. Recurrence and variability of germline EPCAM deletions in Lynch syndrome. Hum Mutat. 2011 Apr; 32(4):407-14. PMID: 21309036.
    Citations: 28     Fields:    Translation:Cells
  74. Kempers MJ, Kuiper RP, Ockeloen CW, Chappuis PO, Hutter P, Rahner N, Schackert HK, Steinke V, Holinski-Feder E, Morak M, Kloor M, Büttner R, Verwiel ET, van Krieken JH, Nagtegaal ID, Goossens M, van der Post RS, Niessen RC, Sijmons RH, Kluijt I, Hogervorst FB, Leter EM, Gille JJ, Aalfs CM, Redeker EJ, Hes FJ, Tops CM, van Nesselrooij BP, van Gijn ME, Gómez García EB, Eccles DM, Bunyan DJ, Syngal S, Stoffel EM, Culver JO, Palomares MR, Graham T, Velsher L, Papp J, Oláh E, Chan TL, Leung SY, van Kessel AG, Kiemeney LA, Hoogerbrugge N, Ligtenberg MJ. Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study. Lancet Oncol. 2011 Jan; 12(1):49-55. PMID: 21145788.
    Citations: 53     Fields:    Translation:HumansCells
  75. Dinh TA, Rosner BI, Atwood JC, Boland CR, Syngal S, Vasen HF, Gruber SB, Burt RW. Health benefits and cost-effectiveness of primary genetic screening for Lynch syndrome in the general population. Cancer Prev Res (Phila). 2011 Jan; 4(1):9-22. PMID: 21088223.
    Citations: 55     Fields:    Translation:Humans
  76. Grover S, Syngal S. Hereditary pancreatic cancer. Gastroenterology. 2010 Oct; 139(4):1076-80, 1080.e1-2. PMID: 20727885.
    Citations: 26     Fields:    Translation:Humans
  77. Kastrinos F, Steyerberg EW, Mercado R, Balmaña J, Holter S, Gallinger S, Siegmund KD, Church JM, Jenkins MA, Lindor NM, Thibodeau SN, Burbidge LA, Wenstrup RJ, Syngal S. The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history. Gastroenterology. 2011 Jan; 140(1):73-81. PMID: 20727894.
    Citations: 55     Fields:    Translation:HumansCells
  78. Stoffel EM, Mercado RC, Kohlmann W, Ford B, Grover S, Conrad P, Blanco A, Shannon KM, Powell M, Chung DC, Terdiman J, Gruber SB, Syngal S. Prevalence and predictors of appropriate colorectal cancer surveillance in Lynch syndrome. Am J Gastroenterol. 2010 Aug; 105(8):1851-60. PMID: 20354509.
    Citations: 25     Fields:    Translation:HumansPHPublic Health
  79. Goel A, Xicola RM, Nguyen TP, Doyle BJ, Sohn VR, Bandipalliam P, Rozek LS, Reyes J, Cordero C, Balaguer F, Castells A, Jover R, Andreu M, Syngal S, Boland CR, Llor X. Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency. Gastroenterology. 2010 May; 138(5):1854-62. PMID: 20102720.
    Citations: 52     Fields:    Translation:HumansCells
  80. Ruffin MT, Normolle DP, Evelegh MJ, Baron JA, Bresalier RS, Marcon NE, Syngal S, Turgeon DK, Tuck MK, Brenner DE. Rectal mucosal quantitative galactose oxidase-Schiff reaction as an early detection biomarker for colorectal cancer: comparison to fecal occult stool blood test. Cancer Biomark. 2010-2011; 8(2):109-12. PMID: 21896998.
    Citations:    Fields:    Translation:Humans
  81. Grover S, Syngal S. Risk assessment, genetic testing, and management of Lynch syndrome. J Natl Compr Canc Netw. 2010 Jan; 8(1):98-105. PMID: 20064292.
    Citations: 9     Fields:    Translation:Humans
  82. Kastrinos F, Mukherjee B, Tayob N, Wang F, Sparr J, Raymond VM, Bandipalliam P, Stoffel EM, Gruber SB, Syngal S. Risk of pancreatic cancer in families with Lynch syndrome. JAMA. 2009 Oct 28; 302(16):1790-5. PMID: 19861671.
    Citations: 119     Fields:    Translation:HumansCells
  83. Mueller J, Gazzoli I, Bandipalliam P, Garber JE, Syngal S, Kolodner RD. Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases. Cancer Res. 2009 Sep 01; 69(17):7053-61. PMID: 19690142.
    Citations: 17     Fields:    Translation:HumansCellsPHPublic Health
  84. Grover S, Stoffel EM, Mercado RC, Ford BM, Kohlman WK, Shannon KM, Conrad PG, Blanco AM, Terdiman JP, Gruber SB, Chung DC, Syngal S. Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome. J Clin Oncol. 2009 Aug 20; 27(24):3981-6. PMID: 19620492.
    Citations: 11     Fields:    Translation:HumansCells
  85. Stoffel E, Mukherjee B, Raymond VM, Tayob N, Kastrinos F, Sparr J, Wang F, Bandipalliam P, Syngal S, Gruber SB. Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome. Gastroenterology. 2009 Nov; 137(5):1621-7. PMID: 19622357.
    Citations: 97     Fields:    Translation:HumansCells
  86. Shelton RC, Puleo E, Syngal S, Emmons KM. Multivitamin use among multi-ethnic, low-income adults. Cancer Causes Control. 2009 Oct; 20(8):1271-80. PMID: 19412739.
    Citations: 3     Fields:    Translation:Humans
  87. Kastrinos F, Allen JI, Stockwell DH, Stoffel EM, Cook EF, Mutinga ML, Balmaña J, Syngal S. Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy. Am J Gastroenterol. 2009 Jun; 104(6):1508-18. PMID: 19491864.
    Citations: 20     Fields:    Translation:Humans
  88. Sparr JA, Bandipalliam P, Redston MS, Syngal S. Intraductal papillary mucinous neoplasm of the pancreas with loss of mismatch repair in a patient with Lynch syndrome. Am J Surg Pathol. 2009 Feb; 33(2):309-12. PMID: 18987546.
    Citations: 10     Fields:    Translation:HumansCells
  89. Emmons KM, Lobb R, Puleo E, Bennett G, Stoffel E, Syngal S. Colorectal cancer screening: prevalence among low-income groups with health insurance. Health Aff (Millwood). 2009 Jan-Feb; 28(1):169-77. PMID: 19124867.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  90. Grover S, Syngal S. Genetic testing in gastroenterology: Lynch syndrome. Best Pract Res Clin Gastroenterol. 2009; 23(2):185-96. PMID: 19414145.
    Citations: 6     Fields:    Translation:Humans
  91. Stoffel EM, Turgeon DK, Stockwell DH, Normolle DP, Tuck MK, Marcon NE, Baron JA, Bresalier RS, Arber N, Ruffin MT, Syngal S, Brenner DE. Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying. Cancer Prev Res (Phila). 2008 Dec; 1(7):507-13. PMID: 19139000.
    Citations: 10     Fields:    Translation:Humans
  92. Byfield SA, Syngal S. Clinical guidelines versus universal molecular testing: are we ready to choose an optimal strategy for Lynch syndrome identification? Am J Gastroenterol. 2008 Nov; 103(11):2837-40. PMID: 19032469.
    Citations: 4     Fields:    Translation:Humans
  93. Stoffel EM, Turgeon DK, Stockwell DH, Zhao L, Normolle DP, Tuck MK, Bresalier RS, Marcon NE, Baron JA, Ruffin MT, Brenner DE, Syngal S. Missed adenomas during colonoscopic surveillance in individuals with Lynch Syndrome (hereditary nonpolyposis colorectal cancer). Cancer Prev Res (Phila). 2008 Nov; 1(6):470-5. PMID: 19138994.
    Citations: 28     Fields:    Translation:HumansPHPublic Health
  94. Strate LL, Liu YL, Aldoori WH, Syngal S, Giovannucci EL. Obesity increases the risks of diverticulitis and diverticular bleeding. Gastroenterology. 2009 Jan; 136(1):115-122.e1. PMID: 18996378.
    Citations: 79     Fields:    Translation:Humans
  95. Liu W, Syngal S, Zellos L. Gastropericardial fistula-induced pericarditis: an unusual consequence of GERD. Medscape J Med. 2008; 10(9):205. PMID: 19008967.
    Citations: 1     Fields:    Translation:Humans
  96. Strate LL, Liu YL, Syngal S, Aldoori WH, Giovannucci EL. Nut, corn, and popcorn consumption and the incidence of diverticular disease. JAMA. 2008 Aug 27; 300(8):907-14. PMID: 18728264.
    Citations: 44     Fields:    Translation:HumansAnimals
  97. Kastrinos F, Stoffel EM, Balmaña J, Steyerberg EW, Mercado R, Syngal S. Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States. Cancer Epidemiol Biomarkers Prev. 2008 Aug; 17(8):2044-51. PMID: 18708397.
    Citations: 20     Fields:    Translation:HumansCells
  98. Balmaña J, Balaguer F, Castellví-Bel S, Steyerberg EW, Andreu M, Llor X, Jover R, Castells A, Syngal S. Comparison of predictive models, clinical criteria and molecular tumour screening for the identification of patients with Lynch syndrome in a population-based cohort of colorectal cancer patients. J Med Genet. 2008 Sep; 45(9):557-63. PMID: 18603628.
    Citations: 21     Fields:    Translation:Humans
  99. Strate LL, Ayanian JZ, Kotler G, Syngal S. Risk factors for mortality in lower intestinal bleeding. Clin Gastroenterol Hepatol. 2008 Sep; 6(9):1004-10; quiz 955-. PMID: 18558513.
    Citations: 38     Fields:    Translation:Humans
  100. Emmons K, Puleo E, McNeill LH, Bennett G, Chan S, Syngal S. Colorectal cancer screening awareness and intentions among low income, sociodemographically diverse adults under age 50. Cancer Causes Control. 2008 Dec; 19(10):1031-41. PMID: 18478340.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  101. Masciari S, Van den Abbeele AD, Diller LR, Rastarhuyeva I, Yap J, Schneider K, Digianni L, Li FP, Fraumeni JF, Syngal S, Garber JE. F18-fluorodeoxyglucose-positron emission tomography/computed tomography screening in Li-Fraumeni syndrome. JAMA. 2008 Mar 19; 299(11):1315-9. PMID: 18349092.
    Citations: 31     Fields:    Translation:Humans
  102. Stoffel EM, Ford B, Mercado RC, Punglia D, Kohlmann W, Conrad P, Blanco A, Shannon KM, Powell M, Gruber SB, Terdiman J, Chung DC, Syngal S. Sharing genetic test results in Lynch syndrome: communication with close and distant relatives. Clin Gastroenterol Hepatol. 2008 Mar; 6(3):333-8. PMID: 18258490.
    Citations: 27     Fields:    Translation:Humans
  103. Steyerberg EW, Balmaña J, Stockwell DH, Syngal S. Data reduction for prediction: a case study on robust coding of age and family history for the risk of having a genetic mutation. Stat Med. 2007 Dec 30; 26(30):5545-56. PMID: 17948867.
    Citations: 3     Fields:    Translation:HumansCells
  104. Balaguer F, Balmaña J, Castellví-Bel S, Steyerberg EW, Andreu M, Llor X, Jover R, Syngal S, Castells A. Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients. Gastroenterology. 2008 Jan; 134(1):39-46. PMID: 18061181.
    Citations: 20     Fields:    Translation:HumansCells
  105. Kastrinos F, Syngal S. Recently identified colon cancer predispositions: MYH and MSH6 mutations. Semin Oncol. 2007 Oct; 34(5):418-24. PMID: 17920897.
    Citations: 8     Fields:    Translation:Humans
  106. Klein AP, de Andrade M, Hruban RH, Bondy M, Schwartz AG, Gallinger S, Lynch HT, Syngal S, Rabe KG, Goggins MG, Petersen GM. Linkage analysis of chromosome 4 in families with familial pancreatic cancer. Cancer Biol Ther. 2007 Mar; 6(3):320-3. PMID: 17312386.
    Citations: 5     Fields:    Translation:HumansCells
  107. Kastrinos F, Stoffel EM, Balmaña J, Syngal S. Attitudes toward prenatal genetic testing in patients with familial adenomatous polyposis. Am J Gastroenterol. 2007 Jun; 102(6):1284-90. PMID: 17355417.
    Citations: 10     Fields:    Translation:Humans
  108. Murff HJ, Greevy RA, Syngal S. The comprehensiveness of family cancer history assessments in primary care. Community Genet. 2007; 10(3):174-80. PMID: 17575462.
    Citations: 34     Fields:    Translation:HumansPHPublic Health
  109. Balmaña J, Stockwell DH, Steyerberg EW, Stoffel EM, Deffenbaugh AM, Reid JE, Ward B, Scholl T, Hendrickson B, Tazelaar J, Burbidge LA, Syngal S. Prediction of MLH1 and MSH2 mutations in Lynch syndrome. JAMA. 2006 Sep 27; 296(12):1469-78. PMID: 17003395.
    Citations: 50     Fields:    Translation:Humans
  110. Ford BM, Evans JS, Stoffel EM, Balmaña J, Regan MM, Syngal S. Factors associated with enrollment in cancer genetics research. Cancer Epidemiol Biomarkers Prev. 2006 Jul; 15(7):1355-9. PMID: 16835336.
    Citations: 15     Fields:    Translation:Humans
  111. Brenner DE, Su Y, Normolle DP, Syngal S, Bresalier R, Marcon N, Baron J, Block T. Detection of colorectal neoplasia associated K-Ras mutations in human urine. J Clin Oncol. 2006 Jun 20; 24(18_suppl):1005. PMID: 27953835.
    Citations:    
  112. Petersen GM, de Andrade M, Goggins M, Hruban RH, Bondy M, Korczak JF, Gallinger S, Lynch HT, Syngal S, Rabe KG, Seminara D, Klein AP. Pancreatic cancer genetic epidemiology consortium. Cancer Epidemiol Biomarkers Prev. 2006 Apr; 15(4):704-10. PMID: 16614112.
    Citations: 59     Fields:    Translation:Humans
  113. Syngal S, Stoffel E, Chung D, Willett C, Schoetz D, Schroy P, Jagadeesh D, Morel K, Ross M. Detection of stool DNA mutations before and after treatment of colorectal neoplasia. Cancer. 2006 Jan 15; 106(2):277-83. PMID: 16342248.
    Citations: 14     Fields:    Translation:Humans
  114. Wong P, Verselis SJ, Garber JE, Schneider K, DiGianni L, Stockwell DH, Li FP, Syngal S. Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome. Gastroenterology. 2006 Jan; 130(1):73-9. PMID: 16401470.
    Citations: 23     Fields:    Translation:Humans
  115. Jo WS, Bandipalliam P, Shannon KM, Niendorf KB, Chan-Smutko G, Hur C, Syngal S, Chung DC. Correlation of polyp number and family history of colon cancer with germline MYH mutations. Clin Gastroenterol Hepatol. 2005 Oct; 3(10):1022-8. PMID: 16234049.
    Citations: 11     Fields:    Translation:Humans
  116. Strate LL, Saltzman JR, Ookubo R, Mutinga ML, Syngal S. Validation of a clinical prediction rule for severe acute lower intestinal bleeding. Am J Gastroenterol. 2005 Aug; 100(8):1821-7. PMID: 16086720.
    Citations: 15     Fields:    Translation:Humans
  117. Balmaña J, Stoffel EM, Stockwell DH, Steyerberg EW, Deffenbauch AM, Reid JE, Hendrickson BC, Scholl T, Noll WW, Syngal S. Performance of the Revised Bethesda guidelines for identification of hereditary nonpolyposis colorectal cancer (HNPCC) mutation carriers. J Clin Oncol. 2005 Jun; 23(16_suppl):9506. PMID: 27946690.
    Citations:    
  118. Evans JS, Ford BM, Balmaña J, Stoffel EM, Mayer RJ, Syngal S. Factors predicting willingness to participate in cancer genetic epidemiologic research. J Clin Oncol. 2005 Jun; 23(16_suppl):6007. PMID: 27945111.
    Citations:    
  119. Stoffel EM, Syngal S. Adenomas in young patients: what is the optimal evaluation? Am J Gastroenterol. 2005 May; 100(5):1150-3. PMID: 15842592.
    Citations: 5     Fields:    Translation:HumansCells
  120. Strate LL, Syngal S. Hereditary colorectal cancer syndromes. Cancer Causes Control. 2005 Apr; 16(3):201-13. PMID: 15947872.
    Citations: 30     Fields:    Translation:Humans
  121. Lu KH, Dinh M, Kohlmann W, Watson P, Green J, Syngal S, Bandipalliam P, Chen LM, Allen B, Conrad P, Terdiman J, Sun C, Daniels M, Burke T, Gershenson DM, Lynch H, Lynch P, Broaddus RR. Gynecologic cancer as a "sentinel cancer" for women with hereditary nonpolyposis colorectal cancer syndrome. Obstet Gynecol. 2005 Mar; 105(3):569-74. PMID: 15738026.
    Citations: 50     Fields:    Translation:Humans
  122. Strate LL, Syngal S. Predictors of utilization of early colonoscopy vs. radiography for severe lower intestinal bleeding. Gastrointest Endosc. 2005 Jan; 61(1):46-52. PMID: 15672055.
    Citations: 15     Fields:    Translation:Humans
  123. Syngal S, Bandipalliam P, Boland CR. Surveillance of patients at high risk for colorectal cancer. Med Clin North Am. 2005 Jan; 89(1):61-84, vii-viii. PMID: 15527809.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  124. Agrawal J, Syngal S. Colon cancer screening strategies. Curr Opin Gastroenterol. 2005 Jan; 21(1):59-63. PMID: 15687886.
    Citations: 6     Fields:    Translation:Humans
  125. Whitney D, Skoletsky J, Moore K, Boynton K, Kann L, Brand R, Syngal S, Lawson M, Shuber A. Enhanced retrieval of DNA from human fecal samples results in improved performance of colorectal cancer screening test. J Mol Diagn. 2004 Nov; 6(4):386-95. PMID: 15507679.
    Citations: 14     Fields:    Translation:HumansPHPublic Health
  126. Murff HJ, Byrne D, Syngal S. Cancer risk assessment: quality and impact of the family history interview. Am J Prev Med. 2004 Oct; 27(3):239-45. PMID: 15450637.
    Citations: 32     Fields:    Translation:Humans
  127. Murff HJ, Spigel DR, Syngal S. Does this patient have a family history of cancer? An evidence-based analysis of the accuracy of family cancer history. JAMA. 2004 Sep 22; 292(12):1480-9. PMID: 15383520.
    Citations: 105     Fields:    Translation:Humans
  128. Grover S, Stoffel EM, Bussone L, Tschoegl E, Syngal S. Physician assessment of family cancer history and referral for genetic evaluation in colorectal cancer patients. Clin Gastroenterol Hepatol. 2004 Sep; 2(9):813-9. PMID: 15354282.
    Citations: 49     Fields:    Translation:Humans
  129. Murff HJ, Rothman RL, Byrne DW, Syngal S. The impact of family history of diabetes on glucose testing and counseling behavior in primary care. Diabetes Care. 2004 Sep; 27(9):2247-8. PMID: 15333494.
    Citations: 8     Fields:    Translation:Humans
  130. Bandipalliam P, Balmana J, Syngal S. Comprehensive genetic and endoscopic evaluation may be necessary to distinguish sporadic versus familial adenomatous polyposis-associated abdominal desmoid tumors. Surgery. 2004 Jun; 135(6):683-9. PMID: 15179376.
    Citations:    Fields:    Translation:HumansCells
  131. Su YH, Wang M, Brenner DE, Ng A, Melkonyan H, Umansky S, Syngal S, Block TM. Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer. J Mol Diagn. 2004 May; 6(2):101-7. PMID: 15096565.
    Citations: 53     Fields:    Translation:HumansCells
  132. Lao CD, Simmons M, Syngal S, Bresalier RS, Fortlage L, Normolle D, Griffith KA, Appelman HD, Brenner DE. Dysplasia in Barrett esophagus. Cancer. 2004 Apr 15; 100(8):1622-7. PMID: 15073848.
    Citations: 4     Fields:    Translation:Humans
  133. Balmaña J, Stoffel EM, Emmons KM, Garber JE, Syngal S. Comparison of motivations and concerns for genetic testing in hereditary colorectal and breast cancer syndromes. J Med Genet. 2004 Apr; 41(4):e44. PMID: 15060120.
    Citations: 8     Fields:    Translation:Humans
  134. Bandipalliam P, Garber J, Kolodner RD, Syngal S. Clinical presentation correlates with the type of mismatch repair gene involved in hereditary nonpolyposis colon cancer. Gastroenterology. 2004 Mar; 126(3):936-7. PMID: 14988860.
    Citations: 7     Fields:    Translation:HumansCells
  135. Umar A, Boland CR, Terdiman JP, Syngal S, de la Chapelle A, Rüschoff J, Fishel R, Lindor NM, Burgart LJ, Hamelin R, Hamilton SR, Hiatt RA, Jass J, Lindblom A, Lynch HT, Peltomaki P, Ramsey SD, Rodriguez-Bigas MA, Vasen HF, Hawk ET, Barrett JC, Freedman AN, Srivastava S. Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst. 2004 Feb 18; 96(4):261-8. PMID: 14970275.
    Citations: 689     Fields:    Translation:HumansCells
  136. Telford JJ, Saltzman JR, Kuntz KM, Syngal S. Impact of preoperative staging and chemoradiation versus postoperative chemoradiation on outcome in patients with rectal cancer: a decision analysis. J Natl Cancer Inst. 2004 Feb 04; 96(3):191-201. PMID: 14759986.
    Citations: 1     Fields:    Translation:Humans
  137. Garber JE, Syngal S. One less thing to worry about: the shrinking spectrum of tumors in BRCA founder mutation carriers. J Natl Cancer Inst. 2004 Jan 07; 96(1):2-3. PMID: 14709725.
    Citations: 2     Fields:    Translation:Humans
  138. Stockwell DH, Woo P, Jacobson BC, Remily R, Syngal S, Wolf J, Farraye FA. Determinants of colorectal cancer screening in women undergoing mammography. Am J Gastroenterol. 2003 Aug; 98(8):1875-80. PMID: 12907347.
    Citations: 15     Fields:    Translation:HumansPHPublic Health
  139. Stoffel EM, Garber JE, Grover S, Russo L, Johnson J, Syngal S. Cancer surveillance is often inadequate in people at high risk for colorectal cancer. J Med Genet. 2003 May; 40(5):e54. PMID: 12746408.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  140. Strate LL, Orav EJ, Syngal S. Early predictors of severity in acute lower intestinal tract bleeding. Arch Intern Med. 2003 Apr 14; 163(7):838-43. PMID: 12695275.
    Citations: 29     Fields:    Translation:Humans
  141. Strate LL, Syngal S. Timing of colonoscopy: impact on length of hospital stay in patients with acute lower intestinal bleeding. Am J Gastroenterol. 2003 Feb; 98(2):317-22. PMID: 12591048.
    Citations: 31     Fields:    Translation:Humans
  142. Jagadeesh D, Syngal S. Genetic testing for hereditary nonpolyposis colorectal cancer. Curr Opin Gastroenterol. 2003 Jan; 19(1):57-63. PMID: 15699895.
    Citations:    Fields:    
  143. Stoffel EM, Syngal S. Colon cancer screening strategies. Curr Opin Gastroenterol. 2002 Sep; 18(5):595-601. PMID: 17033339.
    Citations:    Fields:    
  144. Gazzoli I, Loda M, Garber J, Syngal S, Kolodner RD. A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. Cancer Res. 2002 Jul 15; 62(14):3925-8. PMID: 12124320.
    Citations: 66     Fields:    Translation:HumansCells
  145. Wahlberg SS, Schmeits J, Thomas G, Loda M, Garber J, Syngal S, Kolodner RD, Fox E. Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Res. 2002 Jun 15; 62(12):3485-92. PMID: 12067992.
    Citations: 49     Fields:    Translation:HumansCells
  146. Syngal S, Fox EA, Eng C, Kolodner RD, Garber JE. Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. J Med Genet. 2000 Sep; 37(9):641-5. PMID: 10978352.
    Citations: 67     Fields:    Translation:Humans
  147. Syngal S, Schrag D, Falchuk M, Tung N, Farraye FA, Chung D, Wright M, Whetsell A, Miller G, Garber JE. Phenotypic characteristics associated with the APC gene I1307K mutation in Ashkenazi Jewish patients with colorectal polyps. JAMA. 2000 Aug 16; 284(7):857-60. PMID: 10938175.
    Citations: 5     Fields:    Translation:Humans
  148. Syngal S. Hereditary nonpolyposis colorectal cancer: a call for attention. J Clin Oncol. 2000 Jun; 18(11):2189-92. PMID: 10829037.
    Citations: 3     Fields:    Translation:HumansCells
  149. Syngal S, Clarke G, Bandipalliam P. Potential roles of genetic biomarkers in colorectal cancer chemoprevention. J Cell Biochem Suppl. 2000; 34:28-34. PMID: 10762012.
    Citations: 3     Fields:    Translation:Humans
  150. Kolodner RD, Tytell JD, Schmeits JL, Kane MF, Gupta RD, Weger J, Wahlberg S, Fox EA, Peel D, Ziogas A, Garber JE, Syngal S, Anton-Culver H, Li FP. Germ-line msh6 mutations in colorectal cancer families. Cancer Res. 1999 Oct 15; 59(20):5068-74. PMID: 10537275.
    Citations: 83     Fields:    Translation:Humans
  151. Syngal S, Fox EA, Li C, Dovidio M, Eng C, Kolodner RD, Garber JE. Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing. JAMA. 1999 Jul 21; 282(3):247-53. PMID: 10422993.
    Citations: 34     Fields:    Translation:Humans
  152. Syngal S, Coakley EH, Willett WC, Byers T, Williamson DF, Colditz GA. Long-term weight patterns and risk for cholecystectomy in women. Ann Intern Med. 1999 Mar 16; 130(6):471-7. PMID: 10075614.
    Citations: 16     Fields:    Translation:Humans
  153. Syngal S, Weeks JC, Schrag D, Garber JE, Kuntz KM. Benefits of colonoscopic surveillance and prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer mutations. Ann Intern Med. 1998 Nov 15; 129(10):787-96. PMID: 9841584.
    Citations: 37     Fields:    Translation:Humans
  154. Snapper SB, Syngal S, Friedman LS. Ulcerative colitis and colon cancer: more controversy than clarity. Dig Dis. 1998 Mar-Apr; 16(2):81-7. PMID: 9571373.
    Citations: 3     Fields:    Translation:Humans
  155. Donovan JM, Syngal S. Colorectal cancer in women: an underappreciated but preventable risk. J Womens Health. 1998 Feb; 7(1):45-8. PMID: 9511131.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  156. Marsh DJ, Roth S, Lunetta KL, Hemminki A, Dahia PL, Sistonen P, Zheng Z, Caron S, van Orsouw NJ, Bodmer WF, Cottrell SE, Dunlop MG, Eccles D, Hodgson SV, Järvinen H, Kellokumpu I, Markie D, Neale K, Phillips R, Rozen P, Syngal S, Vijg J, Tomlinson IP, Aaltonen LA, Eng C. Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome. Cancer Res. 1997 Nov 15; 57(22):5017-21. PMID: 9371495.
    Citations: 18     Fields:    Translation:HumansCells
  157. Lichtenstein DR, Syngal S, Wolfe MM. Nonsteroidal antiinflammatory drugs and the gastrointestinal tract. The double-edged sword. Arthritis Rheum. 1995 Jan; 38(1):5-18. PMID: 7818572.
    Citations: 33     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Syngal's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (433)
Explore
_
Co-Authors (86)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.