Harvard Catalyst Profiles

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Stephen Thomas Sonis, D.M.Sc., D.M.D.

Title
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Department
Address
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Mentoring
Effects of Sphingomyelinase Inhibitor on Ionizing Radiation-Induced Apoptosis
Part Time/Continuation, 01/03/01 - 05/31/01
The Role of Endothelial Cell Injury in the Development of Oral Mucositis
Part Time/Continuation, 09/01/00 - 12/31/00
The Rold of Endothelial Cell Injury in the Development of Oral Mucositis
Summer, 06/23/00 - 08/31/00
Treatment of Radiotherapy-Induced Oral Mucositis with In Vivo Blockade of Tumor Necrosis Factor
Part Time/Continuation, 08/01/99 - 06/30/00
Mucositis Research
Summer, 07/01/03 - 08/31/03
Oral Disease and Dental Treatment for Patients Undergoing Cardiac Valve Replacements of Surgical Valve Repair
Part Time, 09/05/01 - 01/31/02
Effects of Sphingomyelinase Inhibitor on Ionizing Radiation-induced Apoptosis
Summer, 06/21/00 - 08/30/00
Development of a Murine Model of Chemotherapy-induced Ulcerative Mucositis and the Treatment of Oral Mucositis with In Vivo Blockade of Tumor Necrosis Factor-X
Part Time/Continuation, 10/01/98 - 06/30/99
Effects of Sphingomyelinase Inhibitor on Ionizing Radiation-Induced Apoptosis
Part Time/Continuation, 09/01/00 - 12/31/00
Therapy-Related Oral and Maxillofacial Complications in Hodgkin’s Lymphoma Survivors: A Sib-Pair Analysis
Summer, 06/15/09 - 08/10/09

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13DE013663 (SONIS, STEPHEN T) May 1, 2000 - Apr 30, 2001
    NIH
    MUCOSAL INJURY IN CANCER PATIENTS
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Choi SE, Choudhary A, Huang J, Sonis S, Giuliano AR, Villa A. Increasing HPV vaccination coverage to prevent oropharyngeal cancer: A cost-effectiveness analysis. Tumour Virus Res. 2021 Dec 30; 13:200234. PMID: 34974194.
    Citations:    Fields:    
  2. Yaroslavsky AN, Juliano AF, Adnan A, Selting WJ, Iorizzo TW, Carroll JD, Sonis ST, Duncan CN, London WB, Treister NS. Validation of a Monte Carlo Modelling Based Dosimetry of Extraoral Photobiomodulation. Diagnostics (Basel). 2021 Nov 26; 11(12). PMID: 34943447.
    Citations:    
  3. Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST. The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies. CA Cancer J Clin. 2022 01; 72(1):57-77. PMID: 34714553.
    Citations:    Fields:    Translation:HumansPHPublic Health
  4. Sonis S, Patel J, Ashbury FD. The application of "Omics" to accelerate precision medicine in Supportive Care in Cancer. Support Care Cancer. 2021 Dec; 29(12):7143-7144. PMID: 34546453.
    Citations:    Fields:    Translation:Humans
  5. Klein BA, Alves FA, de Santana Rodrigues Velho J, Vacharotayangul P, Hanna GJ, LeBoeuf NR, Shazib MA, Villa A, Woo SB, Sroussi H, Sonis S, Treister NS. Oral manifestations of immune-related adverse events in cancer patients treated with immune checkpoint inhibitors. Oral Dis. 2022 Jan; 28(1):9-22. PMID: 34265157.
    Citations: 1     Fields:    Translation:Humans
  6. Adnan A, Yaroslavsky AN, Carroll JD, Selting W, Juliano AF, London WB, Sonis ST, Duncan CN, Treister NS. The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis. Front Oral Health. 2021; 2:689386. PMID: 35048034.
    Citations:    
  7. Sonis S, Villa A, Epstein J. Exceptional toxicity resistance. Support Care Cancer. 2021 May; 29(5):2263-2264. PMID: 33594509.
    Citations:    Fields:    
  8. Villa A, Vollemans M, De Moraes A, Sonis S. Concordance of the WHO, RTOG, and CTCAE v4.0 grading scales for the evaluation of oral mucositis associated with chemoradiation therapy for the treatment of oral and oropharyngeal cancers. Support Care Cancer. 2021 Oct; 29(10):6061-6068. PMID: 33788003.
    Citations: 1     Fields:    Translation:Humans
  9. Pulsipher A, Savage JR, Kennedy TP, Gupta K, Cuiffo BG, Sonis ST, Lee WY. GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling. PLoS One. 2021; 16(3):e0249343. PMID: 33770116.
    Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
  10. Sonis ST. A hypothesis for the pathogenesis of radiation-induced oral mucositis: when biological challenges exceed physiologic protective mechanisms. Implications for pharmacological prevention and treatment. Support Care Cancer. 2021 Sep; 29(9):4939-4947. PMID: 33712912.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  11. Sonis ST. Superoxide Dismutase as an Intervention for Radiation Therapy-Associated Toxicities: Review and Profile of Avasopasem Manganese as a Treatment Option for Radiation-Induced Mucositis. Drug Des Devel Ther. 2021; 15:1021-1029. PMID: 33716500.
    Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
  12. Sonis ST. Treatment for Oral Mucositis-Current Options and an Update of Small Molecules Under Development. Curr Treat Options Oncol. 2021 02 17; 22(3):25. PMID: 33595722.
    Citations:    Fields:    Translation:Humans
  13. Xu Y, Wen N, Sonis ST, Villa A. Oral side effects of immune checkpoint inhibitor therapy (ICIT): An analysis of 4683 patients receiving ICIT for malignancies at Massachusetts General Hospital, Brigham & Women's Hospital, and the Dana-Farber Cancer Institute, 2011 to 2019. Cancer. 2021 06 01; 127(11):1796-1804. PMID: 33595843.
    Citations: 1     Fields:    Translation:Humans
  14. Choi SE, Choudhary A, Sonis S, Villa A. Benefits of the Involvement of Dentists in Managing Oral Complications Among Patients With Oral Cavity and Oropharyngeal Cancer: An Analysis of Claims Data. JCO Oncol Pract. 2021 11; 17(11):e1668-e1677. PMID: 33555929.
    Citations:    Fields:    Translation:Humans
  15. Sankaran SP, Sonis S. Network meta-analysis from a pairwise meta-analysis design: to assess the comparative effectiveness of oral care interventions in preventing ventilator-associated pneumonia in critically ill patients. Clin Oral Investig. 2021 May; 25(5):2439-2447. PMID: 33537946.
    Citations: 1     Fields:    Translation:Humans
  16. Epstein JB, Dean DR, Sonis ST. Industry and MASCC-an opportunity not to be missed. Support Care Cancer. 2021 Feb; 29(2):559-561. PMID: 33215315.
    Citations:    Fields:    Translation:Humans
  17. Sankaran SP, Villa A, Sonis S. Healthcare-associated infections among patients hospitalized for cancers of the lip, oral cavity and pharynx. Infect Prev Pract. 2021 Mar; 3(1):100115. PMID: 34368735.
    Citations:    
  18. Wardill HR, Sonis ST, Blijlevens NMA, Van Sebille YZA, Ciorba MA, Loeffen EAH, Cheng KKF, Bossi P, Porcello L, Castillo DA, Elad S, Bowen JM. Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action. Support Care Cancer. 2020 Nov; 28(11):5059-5073. PMID: 32592033.
    Citations: 1     Fields:    Translation:Humans
  19. Satheeshkumar PS, Papatheodorou S, Sonis S. Enhanced oral hygiene interventions as a risk mitigation strategy for the prevention of non-ventilator-associated pneumonia: a systematic review and meta-analysis. Br Dent J. 2020 04; 228(8):615-622. PMID: 32332964.
    Citations: 5     Fields:    Translation:Humans
  20. Sonis S. Correction to: Could the impact of photobiomodulation on tumor response to radiation be effected by tumor heterogeneity? Support Care Cancer. 2020 Apr; 28(4):2033. PMID: 32025916.
    Citations:    Fields:    
  21. Cernea A, Fernández-Martínez JL, deAndrés-Galiana EJ, Fernández-Ovies FJ, Alvarez-Machancoses O, Fernández-Muñiz Z, Saligan LN, Sonis ST. Robust pathway sampling in phenotype prediction. Application to triple negative breast cancer. BMC Bioinformatics. 2020 Mar 11; 21(Suppl 2):89. PMID: 32164540.
    Citations: 2     Fields:    Translation:Humans
  22. Villa A, Sonis ST. An update on pharmacotherapies in active development for the management of cancer regimen-associated oral mucositis. Expert Opin Pharmacother. 2020 Apr; 21(5):541-548. PMID: 31990597.
    Citations: 5     Fields:    Translation:Humans
  23. Sonis S. Could the impact of photobiomodulation on tumor response to radiation be effected by tumor heterogeneity? Support Care Cancer. 2020 02; 28(2):423-424. PMID: 31720803.
    Citations: 4     Fields:    
  24. Giralt J, Tao Y, Kortmann RD, Zasadny X, Contreras-Martinez J, Ceruse P, Arias de la Vega F, Lalla RV, Ozsahin EM, Pajkos G, Mazar A, Attali P, Bossi P, Vasseur B, Sonis S, Henke M, Bensadoun RJ. Randomized Phase 2 Trial of a Novel Clonidine Mucoadhesive Buccal Tablet for the Amelioration of Oral Mucositis in Patients Treated With Concomitant Chemoradiation Therapy for Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2020 02 01; 106(2):320-328. PMID: 31669562.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  25. Anderson CM, Lee CM, Saunders DP, Curtis A, Dunlap N, Nangia C, Lee AS, Gordon SM, Kovoor P, Arevalo-Araujo R, Bar-Ad V, Peddada A, Colvett K, Miller D, Jain AK, Wheeler J, Blakaj D, Bonomi M, Agarwala SS, Garg M, Worden F, Holmlund J, Brill JM, Downs M, Sonis ST, Katz S, Buatti JM. Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer. J Clin Oncol. 2019 12 01; 37(34):3256-3265. PMID: 31618127.
    Citations: 20     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  26. Gupta A, Sonis S, Uppaluri R, Bergmark RW, Villa A. Disparities in Oral Cancer Screening Among Dental Professionals: NHANES 2011-2016. Am J Prev Med. 2019 10; 57(4):447-457. PMID: 31443957.
    Citations: 4     Fields:    Translation:Humans
  27. Lalla RV, Brennan MT, Gordon SM, Sonis ST, Rosenthal DI, Keefe DM. Oral Mucositis Due to High-Dose Chemotherapy and/or Head and Neck Radiation Therapy. J Natl Cancer Inst Monogr. 2019 08 01; 2019(53). PMID: 31425601.
    Citations: 11     Fields:    Translation:Humans
  28. Bowen J, Al-Dasooqi N, Bossi P, Wardill H, Van Sebille Y, Al-Azri A, Bateman E, Correa ME, Raber-Durlacher J, Kandwal A, Mayo B, Nair RG, Stringer A, Ten Bohmer K, Thorpe D, Lalla RV, Sonis S, Cheng K, Elad S. The pathogenesis of mucositis: updated perspectives and emerging targets. Support Care Cancer. 2019 Oct; 27(10):4023-4033. PMID: 31286231.
    Citations: 24     Fields:    Translation:Humans
  29. Ridner SH, Dietrich MS, Sonis ST, Murphy B. Biomarkers Associated with Lymphedema and Fibrosis in Patients with Cancer of the Head and Neck. Lymphat Res Biol. 2018 Nov 28. PMID: 30484735.
    Citations:    Fields:    
  30. Bachour PC, Sonis ST. Predicting mucositis risk associated with cytotoxic cancer treatment regimens: rationale, complexity, and challenges. Curr Opin Support Palliat Care. 2018 06; 12(2):198-210. PMID: 29547492.
    Citations: 3     Fields:    Translation:Humans
  31. Villa A, Sonis S. Oral leukoplakia remains a challenging condition. Oral Dis. 2018 Mar; 24(1-2):179-183. PMID: 29480606.
    Citations: 10     Fields:    Translation:Humans
  32. Sonis ST, Villa A. Phase II investigational oral drugs for the treatment of radio/chemotherapy induced oral mucositis. Expert Opin Investig Drugs. 2018 02; 27(2):147-154. PMID: 29323575.
    Citations: 9     Fields:    Translation:HumansAnimalsPHPublic Health
  33. Reinbolt RE, Sonis S, Timmers CD, Fernández-Martínez JL, Cernea A, de Andrés-Galiana EJ, Hashemi S, Miller K, Pilarski R, Lustberg MB. Genomic risk prediction of aromatase inhibitor-related arthralgia in patients with breast cancer using a novel machine-learning algorithm. Cancer Med. 2018 01; 7(1):240-253. PMID: 29168353.
    Citations: 6     Fields:    Translation:Humans
  34. Gupta A, Sonis ST, Schneider EB, Villa A. Impact of the insurance type of head and neck cancer patients on their hospitalization utilization patterns. Cancer. 2018 02 15; 124(4):760-768. PMID: 29112234.
    Citations: 5     Fields:    Translation:Humans
  35. Sultan A, Hanna GJ, Margalit DN, Chau N, Goguen LA, Marty FM, Rabinowits G, Schoenfeld JD, Sonis ST, Thomas T, Tishler RB, Treister NS, Villa A, Woo SB, Haddad R, Mawardi H. The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana-Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline. Oncologist. 2017 11; 22(11):1413. PMID: 29123016.
    Citations:    Fields:    
  36. Anderson CM, Sonis ST, Lee CM, Adkins D, Allen BG, Sun W, Agarwala SS, Venigalla ML, Chen Y, Zhen W, Mould DR, Holmlund JT, Brill JM, Buatti JM. Phase 1b/2a Trial of the Superoxide Dismutase Mimetic GC4419 to Reduce Chemoradiotherapy-Induced Oral Mucositis in Patients With Oral Cavity or Oropharyngeal Carcinoma. Int J Radiat Oncol Biol Phys. 2018 02 01; 100(2):427-435. PMID: 29174131.
    Citations: 27     Fields:    Translation:HumansCTClinical Trials
  37. Hashemi S, Fernandez Martinez JL, Saligan L, Sonis S. Exploring Genetic Attributions Underlying Radiotherapy-Induced Fatigue in Prostate Cancer Patients. J Pain Symptom Manage. 2017 09; 54(3):326-339. PMID: 28797855.
    Citations:    Fields:    Translation:Humans
  38. Kuten-Shorrer M, Treister NS, Stock S, Kelley JM, Ji YD, Woo SB, Lerman MA, Palmason S, Sonis ST, Villa A. Topical Clonazepam Solution for the Management of Burning Mouth Syndrome: A Retrospective Study. J Oral Facial Pain Headache. 2017 Summer; 31(3):257-263. PMID: 28738111.
    Citations: 1     Translation:Humans
  39. Sultan AS, Zimering Y, Petruzziello G, Alyea EP, Antin JH, Soiffer RJ, Ho VT, Sonis ST, Woo SB, Marty FM, Treister NS. Oral health status and risk of bacteremia following allogeneic hematopoietic cell transplantation. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Sep; 124(3):253-260. PMID: 28823316.
    Citations: 6     Fields:    Translation:Humans
  40. Cinausero M, Aprile G, Ermacora P, Basile D, Vitale MG, Fanotto V, Parisi G, Calvetti L, Sonis ST. New Frontiers in the Pathobiology and Treatment of Cancer Regimen-Related Mucosal Injury. Front Pharmacol. 2017; 8:354. PMID: 28642709.
    Citations: 44     
  41. Kudrimoti M, Curtis A, Azawi S, Worden F, Katz S, Adkins D, Bonomi M, Scott Z, Elder J, Sonis ST, Straube R, Donini O. Dusquetide: Reduction in oral mucositis associated with enduring ancillary benefits in tumor resolution and decreased mortality in head and neck cancer patients. Biotechnol Rep (Amst). 2017 Sep; 15:24-26. PMID: 28649557.
    Citations: 3     
  42. Kuten-Shorrer M, Treister NS, Stock S, Kelley JM, Ji YD, Woo SB, Lerman MA, Palmason S, Sonis ST, Villa A. Safety and tolerability of topical clonazepam solution for management of oral dysesthesia. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Aug; 124(2):146-151. PMID: 28606830.
    Citations:    Fields:    Translation:Humans
  43. Sonis ST. The Chicken or the Egg? Changes in Oral Microbiota as Cause or Consequence of Mucositis During Radiation Therapy. EBioMedicine. 2017 Apr; 18:7-8. PMID: 28330600.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  44. Sultan A, Hanna GJ, Margalit DN, Chau N, Goguen LA, Marty FM, Rabinowits G, Schoenfeld JD, Sonis ST, Thomas T, Tishler RB, Treister NS, Villa A, Woo SB, Haddad R, Mawardi H. The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana-Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline. Oncologist. 2017 03; 22(3):343-350. PMID: 28209748.
    Citations: 14     Fields:    Translation:Humans
  45. Kim DW, Garon EB, Jatoi A, Keefe DM, Lacouture ME, Sonis S, Gernhardt D, Wang T, Giri N, Doherty JP, Nadanaciva S, O'Connell J, Sbar E, Cho BC. Impact of a planned dose interruption of dacomitinib in the treatment of advanced non-small-cell lung cancer (ARCHER 1042). Lung Cancer. 2017 04; 106:76-82. PMID: 28285698.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  46. Sonis S, Andreotta PW, Lyng G. On the pathogenesis of mTOR inhibitor-associated stomatitis (mIAS)-studies using an organotypic model of the oral mucosa. Oral Dis. 2017 Apr; 23(3):347-352. PMID: 27896917.
    Citations: 8     Fields:    Translation:Humans
  47. Fernández-Martínez JL, deAndrés-Galiana EJ, Sonis ST. Genomic data integration in chronic lymphocytic leukemia. J Gene Med. 2017 Jan; 19(1-2). PMID: 27928896.
    Citations: 5     Fields:    Translation:HumansCells
  48. deAndrés-Galiana EJ, Fernández-Martínez JL, Sonis ST. Sensitivity analysis of gene ranking methods in phenotype prediction. J Biomed Inform. 2016 12; 64:255-264. PMID: 27793724.
    Citations: 7     Fields:    Translation:Humans
  49. Kudrimoti M, Curtis A, Azawi S, Worden F, Katz S, Adkins D, Bonomi M, Elder J, Sonis ST, Straube R, Donini O. Dusquetide: A novel innate defense regulator demonstrating a significant and consistent reduction in the duration of oral mucositis in preclinical data and a randomized, placebo-controlled phase 2a clinical study. J Biotechnol. 2016 Dec 10; 239:115-125. PMID: 27746305.
    Citations: 14     Fields:    Translation:HumansAnimalsCTClinical Trials
  50. Deandrés-Galiana EJ, Fernández-Martínez JL, Saligan LN, Sonis ST. Impact of Microarray Preprocessing Techniques in Unraveling Biological Pathways. J Comput Biol. 2016 Dec; 23(12):957-968. PMID: 27494192.
    Citations: 4     Fields:    Translation:HumansCells
  51. Villa A, Sonis ST. Pharmacotherapy for the management of cancer regimen-related oral mucositis. Expert Opin Pharmacother. 2016 Sep; 17(13):1801-7. PMID: 27477002.
    Citations: 14     Fields:    Translation:HumansAnimals
  52. Wardill HR, Mander KA, Van Sebille YZ, Gibson RJ, Logan RM, Bowen JM, Sonis ST. Cytokine-mediated blood brain barrier disruption as a conduit for cancer/chemotherapy-associated neurotoxicity and cognitive dysfunction. Int J Cancer. 2016 Dec 15; 139(12):2635-2645. PMID: 27367824.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  53. Sonis ST. Ultrasound-mediated drug delivery. Oral Dis. 2017 Mar; 23(2):135-138. PMID: 27171556.
    Citations: 1     Fields:    Translation:Humans
  54. deAndrés-Galiana EJ, Fernández-Martínez JL, Sonis ST. Design of Biomedical Robots for Phenotype Prediction Problems. J Comput Biol. 2016 08; 23(8):678-92. PMID: 27347715.
    Citations: 6     Fields:    Translation:Humans
  55. Villa A, Sonis S. Toxicities associated with head and neck cancer treatment and oncology-related clinical trials. Curr Probl Cancer. 2016 Sep - Dec; 40(5-6):244-257. PMID: 27520848.
    Citations: 2     Fields:    Translation:Humans
  56. Lacouture ME, Keefe DM, Sonis S, Jatoi A, Gernhardt D, Wang T, Doherty JP, Giri N, Nadanaciva S, O'Connell J, Sbar E, Piperdi B, Garon EB. A phase II study (ARCHER 1042) to evaluate prophylactic treatment of dacomitinib-induced dermatologic and gastrointestinal adverse events in advanced non-small-cell lung cancer. Ann Oncol. 2016 09; 27(9):1712-8. PMID: 27287210.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  57. Chen P, Mancini M, Sonis ST, Fernandez-Martinez J, Liu J, Cohen EE, Toback FG. A Novel Peptide for Simultaneously Enhanced Treatment of Head and Neck Cancer and Mitigation of Oral Mucositis. PLoS One. 2016; 11(4):e0152995. PMID: 27049860.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  58. Vasconcelos RM, Sanfilippo N, Paster BJ, Kerr AR, Li Y, Ramalho L, Queiroz EL, Smith B, Sonis ST, Corby PM. Host-Microbiome Cross-talk in Oral Mucositis. J Dent Res. 2016 07; 95(7):725-33. PMID: 27053118.
    Citations: 33     Fields:    Translation:Humans
  59. Zecha JA, Raber-Durlacher JE, Nair RG, Epstein JB, Sonis ST, Elad S, Hamblin MR, Barasch A, Migliorati CA, Milstein DM, Genot MT, Lansaat L, van der Brink R, Arnabat-Dominguez J, van der Molen L, Jacobi I, van Diessen J, de Lange J, Smeele LE, Schubert MM, Bensadoun RJ. Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action, dosimetric, and safety considerations. Support Care Cancer. 2016 06; 24(6):2781-92. PMID: 26984240.
    Citations: 51     Fields:    Translation:Humans
  60. Sonis ST, Amaral Mendes R. Could the PI3K canonical pathway be a common link between chronic inflammatory conditions and oral carcinogenesis? J Oral Pathol Med. 2016 Aug; 45(7):469-74. PMID: 26991523.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  61. Sonis ST, Hashemi S, Epstein JB, Nair RG, Raber-Durlacher JE. Could the biological robustness of low level laser therapy (Photobiomodulation) impact its use in the management of mucositis in head and neck cancer patients. Oral Oncol. 2016 Mar; 54:7-14. PMID: 26852286.
    Citations: 38     Fields:    Translation:HumansCellsPHPublic Health
  62. Aprile G, Rihawi K, De Carlo E, Sonis ST. Treatment-related gastrointestinal toxicities and advanced colorectal or pancreatic cancer: A critical update. World J Gastroenterol. 2015 Nov 07; 21(41):11793-803. PMID: 26557003.
    Citations: 8     Fields:    Translation:HumansAnimals
  63. Lau A, Dodson TB, Sonis ST, Kaban LB. An Outcomes Study of 40 Years of Graduates of a General Practice Dental Residency. J Dent Educ. 2015 Aug; 79(8):888-96. PMID: 26246526.
    Citations:    Fields:    Translation:Humans
  64. Villa A, Sonis ST. Mucositis: pathobiology and management. Curr Opin Oncol. 2015 May; 27(3):159-64. PMID: 25774860.
    Citations: 75     Fields:    Translation:Humans
  65. Mawardi HH, Elbadawi LS, Sonis ST. Current understanding of the relationship between periodontal and systemic diseases. Saudi Med J. 2015 Feb; 36(2):150-8. PMID: 25719577.
    Citations: 8     Fields:    Translation:Humans
  66. Villa A, Stock S, Aboalela A, Lerman MA, Woo SB, Sonis ST, Treister NS. Oral Medicine referrals at a hospital-based practice in the United States. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Apr; 119(4):423-9. PMID: 25758844.
    Citations: 5     Fields:    Translation:Humans
  67. Sonis ST. Genomics, personalized medicine, and supportive cancer care. Am Soc Clin Oncol Educ Book. 2015; 9-16. PMID: 25993135.
    Citations: 2     Fields:    Translation:Humans
  68. Wardill HR, Van Sebille YZ, Mander KA, Gibson RJ, Logan RM, Bowen JM, Sonis ST. Toll-like receptor 4 signaling: a common biological mechanism of regimen-related toxicities: an emerging hypothesis for neuropathy and gastrointestinal toxicity. Cancer Treat Rev. 2015 Feb; 41(2):122-8. PMID: 25512119.
    Citations: 10     Fields:    Translation:HumansCells
  69. Villa A, Aboalela A, Luskin KA, Cutler CS, Sonis ST, Woo SB, Peterson DE, Treister NS. Mammalian target of rapamycin inhibitor-associated stomatitis in hematopoietic stem cell transplantation patients receiving sirolimus prophylaxis for graft-versus-host disease. Biol Blood Marrow Transplant. 2015 Mar; 21(3):503-8. PMID: 25482865.
    Citations: 3     Fields:    Translation:HumansCells
  70. Saligan LN, Fernández-Martínez JL, deAndrés-Galiana EJ, Sonis S. Supervised classification by filter methods and recursive feature elimination predicts risk of radiotherapy-related fatigue in patients with prostate cancer. Cancer Inform. 2014; 13:141-52. PMID: 25506196.
    Citations: 16     
  71. Lalla RV, Choquette LE, Curley KF, Dowsett RJ, Feinn RS, Hegde UP, Pilbeam CC, Salner AL, Sonis ST, Peterson DE. Randomized double-blind placebo-controlled trial of celecoxib for oral mucositis in patients receiving radiation therapy for head and neck cancer. Oral Oncol. 2014 Nov; 50(11):1098-103. PMID: 25151488.
    Citations: 9     Fields:    Translation:Humans
  72. Sonis S, Elting L, Keefe D, Nguyen H, Grunberg S, Randolph-Jackson P, Brennan M. Unanticipated frequency and consequences of regimen-related diarrhea in patients being treated with radiation or chemoradiation regimens for cancers of the head and neck or lung. Support Care Cancer. 2015 Feb; 23(2):433-9. PMID: 25123194.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  73. Yuan A, Sonis S. Emerging therapies for the prevention and treatment of oral mucositis. Expert Opin Emerg Drugs. 2014 Sep; 19(3):343-51. PMID: 25102771.
    Citations: 9     Fields:    Translation:HumansAnimals
  74. Keefe DM, Elting LS, Nguyen HT, Grunberg SM, Aprile G, Bonaventura A, Selva-Nayagam S, Barsevick A, Koczwara B, Sonis ST. Risk and outcomes of chemotherapy-induced diarrhea (CID) among patients with colorectal cancer receiving multi-cycle chemotherapy. Cancer Chemother Pharmacol. 2014 Oct; 74(4):675-80. PMID: 25055935.
    Citations: 16     Fields:    Translation:Humans
  75. Allison RR, Ambrad AA, Arshoun Y, Carmel RJ, Ciuba DF, Feldman E, Finkelstein SE, Gandhavadi R, Heron DE, Lane SC, Longo JM, Meakin C, Papadopoulos D, Pruitt DE, Steinbrenner LM, Taylor MA, Wisbeck WM, Yuh GE, Nowotnik DP, Sonis ST. Multi-institutional, randomized, double-blind, placebo-controlled trial to assess the efficacy of a mucoadhesive hydrogel (MuGard) in mitigating oral mucositis symptoms in patients being treated with chemoradiation therapy for cancers of the head and neck. Cancer. 2014 May 01; 120(9):1433-40. PMID: 24877167.
    Citations: 19     Fields:    Translation:Humans
  76. Reisman SA, Lee CY, Meyer CJ, Proksch JW, Sonis ST, Ward KW. Topical application of the synthetic triterpenoid RTA 408 protects mice from radiation-induced dermatitis. Radiat Res. 2014 May; 181(5):512-20. PMID: 24720753.
    Citations: 31     Fields:    Translation:AnimalsCellsPHPublic Health
  77. Guze K, Pawluk HC, Short M, Zeng H, Lorch J, Norris C, Sonis S. Pilot study: Raman spectroscopy in differentiating premalignant and malignant oral lesions from normal mucosa and benign lesions in humans. Head Neck. 2015 Apr; 37(4):511-7. PMID: 24677300.
    Citations: 27     Fields:    Translation:Humans
  78. Mancini ML, Sonis ST. Mechanisms of cellular fibrosis associated with cancer regimen-related toxicities. Front Pharmacol. 2014; 5:51. PMID: 24734020.
    Citations: 21     
  79. Russi EG, Raber-Durlacher JE, Sonis ST. Local and systemic pathogenesis and consequences of regimen-induced inflammatory responses in patients with head and neck cancer receiving chemoradiation. Mediators Inflamm. 2014; 2014:518261. PMID: 24757285.
    Citations: 16     Fields:    Translation:HumansCells
  80. Lalla RV, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM, McGuire DB, Migliorati C, Nicolatou-Galitis O, Peterson DE, Raber-Durlacher JE, Sonis ST, Elad S. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2014 May 15; 120(10):1453-61. PMID: 24615748.
    Citations: 271     Fields:    Translation:Humans
  81. Treister NS, Sonis ST, Woo SB. Community-based dental evaluation program for hematopoietic cell transplantation. J Clin Oncol. 2013 Nov; 31(31_suppl):143. PMID: 28136436.
    Citations:    
  82. Kuten-Shorrer M, Kelley JM, Sonis ST, Treister NS. Placebo effect in burning mouth syndrome: a systematic review. Oral Dis. 2014 Apr; 20(3):e1-6. PMID: 24164777.
    Citations: 7     Fields:    Translation:Humans
  83. Limaye SA, Haddad RI, Cilli F, Sonis ST, Colevas AD, Brennan MT, Hu KS, Murphy BA. Phase 1b, multicenter, single blinded, placebo-controlled, sequential dose escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer receiving induction chemotherapy. Cancer. 2013 Dec 15; 119(24):4268-76. PMID: 24114811.
    Citations: 35     Fields:    Translation:HumansCellsCTClinical Trials
  84. Carlotto A, Hogsett VL, Maiorini EM, Razulis JG, Sonis ST. The economic burden of toxicities associated with cancer treatment: review of the literature and analysis of nausea and vomiting, diarrhoea, oral mucositis and fatigue. Pharmacoeconomics. 2013 Sep; 31(9):753-66. PMID: 23963867.
    Citations: 40     Fields:    Translation:Humans
  85. Al-Dasooqi N, Sonis ST, Bowen JM, Bateman E, Blijlevens N, Gibson RJ, Logan RM, Nair RG, Stringer AM, Yazbeck R, Elad S, Lalla RV. Emerging evidence on the pathobiology of mucositis. Support Care Cancer. 2013 Nov; 21(11):3233-41. PMID: 23842598.
    Citations: 32     Fields:    Translation:Humans
  86. Sonis S, Antin J, Tedaldi M, Alterovitz G. SNP-based Bayesian networks can predict oral mucositis risk in autologous stem cell transplant recipients. Oral Dis. 2013 Oct; 19(7):721-7. PMID: 23809011.
    Citations: 13     Fields:    Translation:Humans
  87. Nicolatou-Galitis O, Nikolaidi A, Athanassiadis I, Papadopoulou E, Sonis S. Oral ulcers in patients with advanced breast cancer receiving everolimus: a case series report on clinical presentation and management. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Aug; 116(2):e110-6. PMID: 23643584.
    Citations: 6     Fields:    Translation:Humans
  88. Al-Dasooqi N, Sonis ST, Bowen JM, Bateman E, Blijlevens N, Gibson RJ, Logan RM, Nair RG, Stringer AM, Yazbeck R, Elad S, Lalla RV. Emerging evidence on the pathobiology of mucositis. Support Care Cancer. 2013 Jul; 21(7):2075-83. PMID: 23604521.
    Citations: 37     Fields:    Translation:Humans
  89. Chin M, Lee CY, Chuang JC, Bumeister R, Wigley WC, Sonis ST, Ward KW, Meyer C. Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesity. Am J Physiol Renal Physiol. 2013 Jun 15; 304(12):F1438-46. PMID: 23594825.
    Citations: 27     Fields:    Translation:Animals
  90. Martins F, de Oliveira MA, Wang Q, Sonis S, Gallottini M, George S, Treister N. A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients. Oral Oncol. 2013 Apr; 49(4):293-8. PMID: 23312237.
    Citations: 26     Fields:    Translation:Humans
  91. Sonis ST. Oral mucositis in head and neck cancer: risk, biology, and management. Am Soc Clin Oncol Educ Book. 2013. PMID: 23714511.
    Citations: 24     Fields:    Translation:HumansAnimalsPHPublic Health
  92. Zombeck JA, Fey EG, Lyng GD, Sonis ST. A clinically translatable mouse model for chemotherapy-related fatigue. Comp Med. 2013; 63(6):491-7. PMID: 24326224.
    Citations: 23     Fields:    Translation:Animals
  93. Wu X, Chen P, Sonis ST, Lingen MW, Berger A, Toback FG. A novel Peptide to treat oral mucositis blocks endothelial and epithelial cell apoptosis. Int J Radiat Oncol Biol Phys. 2012 Jul 01; 83(3):e409-15. PMID: 22420966.
    Citations: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  94. Peterson DE, Keefe DM, Sonis ST. New frontiers in mucositis. Am Soc Clin Oncol Educ Book. 2012; 545-51. PMID: 24451793.
    Citations: 6     Fields:    
  95. Lalla RV, Gordon GB, Schubert M, Silverman S, Hutten M, Sonis ST, LeVeque F, Peterson DE. A randomized, double-blind, placebo-controlled trial of misoprostol for oral mucositis secondary to high-dose chemotherapy. Support Care Cancer. 2012 Aug; 20(8):1797-804. PMID: 21964618.
    Citations: 7     Fields:    Translation:Humans
  96. Sonis S. The quest for effective treatments of mucositis. J Support Oncol. 2011 Sep-Oct; 9(5):170-1. PMID: 22024305.
    Citations: 2     Fields:    Translation:HumansAnimals
  97. de Oliveira MA, Martins E Martins F, Wang Q, Sonis S, Demetri G, George S, Butrynski J, Treister NS. Clinical presentation and management of mTOR inhibitor-associated stomatitis. Oral Oncol. 2011 Oct; 47(10):998-1003. PMID: 21890398.
    Citations: 25     Fields:    Translation:Humans
  98. Alterovitz G, Tuthill C, Rios I, Modelska K, Sonis S. Personalized medicine for mucositis: Bayesian networks identify unique gene clusters which predict the response to gamma-D-glutamyl-L-tryptophan (SCV-07) for the attenuation of chemoradiation-induced oral mucositis. Oral Oncol. 2011 Oct; 47(10):951-5. PMID: 21824803.
    Citations: 9     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  99. Sonis ST. Oral mucositis. Anticancer Drugs. 2011 Aug; 22(7):607-12. PMID: 21709615.
    Citations: 51     Fields:    Translation:HumansAnimalsPHPublic Health
  100. Chen P, Lingen M, Sonis ST, Walsh-Reitz MM, Toback FG. Role of AMP-18 in oral mucositis. Oral Oncol. 2011 Sep; 47(9):831-9. PMID: 21737340.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  101. Papkoff J, Lee H, Singh G, Singh S, Chitta S, Andrew K, Quintel P, Rosenberg JS, Watkins BA, Sonis ST, Tuthill CW. Identification of signaling pathways involved in the mechanism of action of the immunomodulatory peptide gamma-D-glutamyl-L-tryptophan. J Clin Oncol. 2011 May 20; 29(15_suppl):5591. PMID: 28022063.
    Citations:    
  102. Tuthill CW, Papkoff J, Watkins BA, Sonis ST. The effect of the immunomodulatory peptide gamma-D-glutamyl-L-tryptophan in leukemia, lymphoma, and head and neck cancer xenograft models. J Clin Oncol. 2011 May 20; 29(15_suppl):5592. PMID: 28022058.
    Citations:    
  103. Rosenthal RA, Fish B, Hill RP, Huffman KD, Lazarova Z, Mahmood J, Medhora M, Molthen R, Moulder JE, Sonis ST, Tofilon PJ, Doctrow SR. Salen Mn complexes mitigate radiation injury in normal tissues. Anticancer Agents Med Chem. 2011 May 01; 11(4):359-72. PMID: 21453241.
    Citations: 34     Fields:    Translation:HumansAnimalsPHPublic Health
  104. Stashenko P, Van Dyke T, Tully P, Kent R, Sonis S, Tanner AC. Inflammation and genetic risk indicators for early periodontitis in adults. J Periodontol. 2011 Apr; 82(4):588-96. PMID: 21054222.
    Citations: 5