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Tai, Yu-Tzu
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Yu-Tzu Tai, Ph.D.
Title
Research Associate in Medicine
Institution
Dana-Farber Cancer Institute
Department
Medicine
Address
Dana-Farber Cancer Institute
44 Binney St
Boston MA 02115
Phone
617/632-3875
Fax
617/632-2140
vCard
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selected publications
|
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
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|
Oldest
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Most Cited
|
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Timeline
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Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Anderson GSF, Ballester-Beltran J, Giotopoulos G, Guerrero JA, Surget S, Williamson JC, So T, Bloxham D, Aubareda A, Asby R, Walker I, Jenkinson L, Soilleux EJ, Roy JP, Teodósio A, Ficken C, Officer-Jones L, Nasser S, Skerget S, Keats JJ, Greaves P,
Tai YT
,
Anderson KC
, MacFarlane M, Thaventhiran JE, Huntly BJP, Lehner PJ, Chapman MA. Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma. Blood. 2022 04 21; 139(16):2471-2482.
PMID:
35134130
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
Cho SF,
Anderson KC
,
Tai YT
. Microenvironment Is a Key Determinant of Immune Checkpoint Inhibitor Response. Clin Cancer Res. 2022 04 14; 28(8):1479-1481.
PMID:
35121621
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Adamia S, Bhatt S, Wen K,
Chyra Z
, Fell GG,
Tai YT
, Pioso MS, Abiatari I,
Letai A
,
Dorfman DM
,
Hideshima T
,
Anderson KC
. Combination therapy targeting Erk1/2 and CDK4/6i in relapsed refractory multiple myeloma. Leukemia. 2022 04; 36(4):1088-1101.
PMID:
35082402
; PMCID:
PMC8979823
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Yan Y, Qin X, Liu J, Fan H, Yan W, Liu L, Du C, Yu Z, Xu Y, Hao M, Deng S, Sui W, Lyu R, Liu W, Wang Q, Zou D, Hu L, Wang J,
Tai YT
,
Anderson KC
, Zhang L, Cheng T, Zetterberg A,
Munshi NC
, Qiu L, An G. Clonal phylogeny and evolution of critical cytogenetic aberrations in multiple myeloma at single-cell level by QM-FISH. Blood Adv. 2022 01 25; 6(2):441-451.
PMID:
34653241
; PMCID:
PMC8791565
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cho SF, Xing L,
Anderson KC
,
Tai YT
. Promising Antigens for the New Frontier of Targeted Immunotherapy in Multiple Myeloma. Cancers (Basel). 2021 Dec 06; 13(23).
PMID:
34885245
; PMCID:
PMC8657018
.
Citations:
9
Xing L, Wang S,
Liu J
, Yu T, Chen H, Wen K, Li Y, Lin L, Hsieh PA, Cho SF, An G, Qiu L, Kinneer K,
Munshi N
,
Anderson KC
,
Tai YT
. BCMA-Specific ADC MEDI2228 and Daratumumab Induce Synergistic Myeloma Cytotoxicity via IFN-Driven Immune Responses and Enhanced CD38 Expression. Clin Cancer Res. 2021 10 01; 27(19):5376-5388.
PMID:
34301753
; PMCID:
PMC8783926
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Joseph NS,
Tai YT
,
Anderson KC
, Lonial S. Novel Approaches to Treating Relapsed and Refractory Multiple Myeloma with a Focus on Recent Approvals of Belantamab Mafodotin and Selinexor. Clin Pharmacol. 2021; 13:169-180.
PMID:
34434061
.
Citations:
1
Miller PG
,
Sperling AS
,
Brea EJ
,
Leick MB
, Fell GG,
Jan M
, Gohil SH,
Tai YT
,
Munshi NC
,
Wu CJ
,
Neuberg DS
,
Maus MV
,
Jacobson C
,
Gibson CJ
,
Ebert BL
. Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy. Blood Adv. 2021 08 10; 5(15):2982-2986.
PMID:
34342642
; PMCID:
PMC8361461
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Bae J
, Accardi F,
Hideshima T
,
Tai YT
,
Prabhala R
, Shambley A, Wen K, Rowell S,
Richardson PG
,
Munshi NC
,
Anderson KC
. Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma. Leukemia. 2022 01; 36(1):138-154.
PMID:
34290359
; PMCID:
PMC8727303
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Bianchi G
,
Czarnecki PG
, Ho M, Roccaro AM, Sacco A, Kawano Y, Gullà A, Samur AA, Chen T, Wen K,
Tai YT
,
Moscvin M
,
Wu X
, Camci-Unal G, Da Vià MC, Bolli N, Sewastianik T,
Carrasco RD
,
Ghobrial IM
,
Anderson KC
. ROBO1 Promotes Homing, Dissemination, and Survival of Multiple Myeloma within the Bone Marrow Microenvironment. Blood Cancer Discov. 2021 07; 2(4):338-353.
PMID:
34268498
; PMCID:
PMC8265993
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ruiz-Heredia Y, Ortiz-Ruiz A,
Samur MK
, Garrido V, Rufian L, Sanchez R, Aguilar-Garrido P, Barrio S, Martín MA, Bolli N,
Tai YT
, Szalat R,
Fulciniti M
,
Munshi N
, Martínez-López J, Linares M, Gallardo M. Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma. Cancers (Basel). 2021 Jun 25; 13(13).
PMID:
34202390
; PMCID:
PMC8268477
.
Citations:
Liu J
,
Hideshima T
, Xing L, Wang S, Zhou W,
Samur MK
, Sewastianik T, Ogiya D, An G, Gao S, Yang L, Ji T,
Bianchi G
, Wen K,
Tai YT
,
Munshi N
,
Richardson P
,
Carrasco R
, Cang Y,
Anderson KC
. ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment. Sci Adv. 2021 06; 7(23).
PMID:
34088671
; PMCID:
PMC8177702
.
Citations:
1
Fields:
Sci
Science
Translation:
Humans
Kumar S, Buon L,
Talluri S
, Roncador M, Liao C, Zhao J, Shi J,
Chakraborty C
, Gonzalez G,
Tai YT
,
Prabhala R
,
Samur MK
,
Munshi NC
, Shammas MA. Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma. Commun Biol. 2021 05 24; 4(1):617.
PMID:
34031527
.
Citations:
Translation:
Humans
Animals
Cells
Shen YJ, Mishima Y, Shi J, Sklavenitis-Pistofidis R, Redd RA, Moschetta M, Manier S, Roccaro AM, Sacco A,
Tai YT
, Mercier F, Kawano Y, Su NK, Berrios B, Doench JG, Root DE,
Michor F
,
Scadden DT
,
Ghobrial IM
. Progression signature underlies clonal evolution and dissemination of multiple myeloma. Blood. 2021 04 29; 137(17):2360-2372.
PMID:
33150374
; PMCID:
PMC8085483
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Gulla A
,
Morelli E
,
Samur MK
, Botta C,
Hideshima T
,
Bianchi G
,
Fulciniti M
, Malvestiti S,
Prabhala RH
,
Talluri S
, Wen K,
Tai YT
,
Richardson PG
,
Chauhan D
, Sewastianik T,
Carrasco RD
,
Munshi NC
,
Anderson KC
. Bortezomib induces anti-multiple myeloma immune response mediated by cGAS/STING pathway activation. Blood Cancer Discov. 2021 09; 2(5):468-483.
PMID:
34568832
; PMCID:
PMC8462183
.
Citations:
6
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ohguchi H, Park PMC, Wang T, Gryder BE, Ogiya D,
Kurata K
, Zhang X, Li D, Pei C, Masuda T, Johansson C, Wimalasena VK, Kim Y, Hino S, Usuki S, Kawano Y,
Samur MK
,
Tai YT
,
Munshi NC
, Matsuoka M, Ohtsuki S, Nakao M, Minami T, Lauberth S, Khan J, Oppermann U, Durbin AD,
Anderson KC
,
Hideshima T
,
Qi J
. Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma. Blood Cancer Discov. 2021 07; 2(4):370-387.
PMID:
34258103
; PMCID:
PMC8265280
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Samur MK
,
Fulciniti M
, Aktas Samur A, Bazarbachi AH,
Tai YT
,
Prabhala R
, Alonso A,
Sperling AS
, Campbell T, Petrocca F, Hege K, Kaiser S, Loiseau HA,
Anderson KC
,
Munshi NC
. Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma. Nat Commun. 2021 02 08; 12(1):868.
PMID:
33558511
.
Citations:
32
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
CT
Clinical Trials
Ogiya D,
Liu J
, Ohguchi H,
Kurata K
,
Samur MK
,
Tai YT
, Adamia S, Ando K,
Hideshima T
,
Anderson KC
. The JAK-STAT pathway regulates CD38 on myeloma cells in the bone marrow microenvironment: therapeutic implications. Blood. 2020 11 12; 136(20):2334-2345.
PMID:
32844992
; PMCID:
PMC7702477
.
Citations:
20
Fields:
Hem
Hematology
Translation:
Humans
Cells
Yu T, Chaganty B, Lin L, Xing L, Ramakrishnan B, Wen K, Hsieh PA, Wollacott A, Viswanathan K, Adari H, Cho SF, Li Y, Chen H, Yang W, Xu Y, An G, Qiu L,
Munshi N
, Babcock G, Shriver Z, Myette JR,
Anderson KC
,
Tai YT
. VIS832, a novel CD138-targeting monoclonal antibody, potently induces killing of human multiple myeloma and further synergizes with IMiDs or bortezomib in vitro and in vivo. Blood Cancer J. 2020 11 02; 10(11):110.
PMID:
33149123
.
Citations:
8
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Nadeem O
,
Tai YT
,
Anderson KC
. Immunotherapeutic and Targeted Approaches in Multiple Myeloma. Immunotargets Ther. 2020; 9:201-215.
PMID:
33117743
.
Citations:
6
Cho SF, Lin L, Xing L, Li Y, Wen K, Yu T, Hsieh PA,
Munshi N
, Wahl J, Matthes K, Friedrich M, Arvedson T,
Anderson KC
,
Tai YT
. The immunomodulatory drugs lenalidomide and pomalidomide enhance the potency of AMG 701 in multiple myeloma preclinical models. Blood Adv. 2020 09 08; 4(17):4195-4207.
PMID:
32898244
.
Citations:
16
Fields:
Hem
Hematology
Translation:
Humans
Animals
Zhu C, Song Z, Wang A, Srinivasan S, Yang G, Greco R, Theilhaber J, Shehu E, Wu L, Yang ZY, Passe-Coutrin W, Fournier A,
Tai YT
,
Anderson KC
, Wiederschain D, Bahjat K, Adrián FJ, Chiron M. Isatuximab Acts Through Fc-Dependent, Independent, and Direct Pathways to Kill Multiple Myeloma Cells. Front Immunol. 2020; 11:1771.
PMID:
32922390
.
Citations:
19
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Xu Y,
Fulciniti M
,
Samur MK
, Ho M,
Deng S
, Liu L, Wen K, Yu T,
Chyra Z
, Dereibal S, Zhang L, Yao Y,
Chakraborty C
,
Morelli E
, Li N, Lopez MA, Perini T, Mu S, An G, Alonso R,
Bianchi G
,
Tai YT
,
Anderson KC
, Qiu L,
Munshi NC
. YWHAE/14-3-3e expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma. Blood. 2020 07 23; 136(4):468-479.
PMID:
32187357
; PMCID:
PMC7378455
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
Lin L, Cho SF, Xing L, Wen K, Li Y, Yu T, Hsieh PA, Chen H, Kurtoglu M, Zhang Y, Andrew Stewart C,
Munshi N
,
Anderson KC
,
Tai YT
. Preclinical evaluation of CD8+ anti-BCMA mRNA CAR T cells for treatment of multiple myeloma. Leukemia. 2021 03; 35(3):752-763.
PMID:
32632095
.
Citations:
21
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Mao XH, Zhuang JL, Zhao DD, Li XQ, Du X, Hao M, Xu Y, Yan YT, Liu JH, Fan HS, Sui WW, Deng SH, Li CW, Zhao JW, Yi SH, Du CX, Zou DH, Li ZJ, Zhao YZ, Zhan FH,
Tai YT
, Fang BJ, Song YP, Wang JX,
Anderson KC
, Qiu LG, An G. IgH translocation with undefined partners is associated with superior outcome in multiple myeloma patients. Eur J Haematol. 2020 Sep; 105(3):326-334.
PMID:
32421883
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Cells
Cho SF, Lin L, Xing L, Li Y, Yu T,
Anderson KC
,
Tai YT
. BCMA-Targeting Therapy: Driving a New Era of Immunotherapy in Multiple Myeloma. Cancers (Basel). 2020 Jun 05; 12(6).
PMID:
32516895
; PMCID:
PMC7352710
.
Citations:
18
Yu T, Xu Y, An G,
Tai YT
, Ho M, Li Z,
Deng S
, Zou D, Yu Z, Hao M,
Anderson KC
, Qiu L. Primary Plasma Cell Leukemia: Real-World Retrospective Study of 46 Patients From a Single-Center Study in China. Clin Lymphoma Myeloma Leuk. 2020 10; 20(10):e652-e659.
PMID:
32624447
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Bustoros M, Sklavenitis-Pistofidis R, Park J, Redd R, Zhitomirsky B, Dunford AJ, Salem K,
Tai YT
, Anand S, Mouhieddine TH, Chavda SJ, Boehner C, Elagina L, Neuse CJ, Cha J,
Rahmat M
, Taylor-Weiner A,
Van Allen E
, Kumar S, Kastritis E, Leshchiner I,
Morgan EA
,
Laubach J
, Casneuf T,
Richardson P
,
Munshi NC
,
Anderson KC
,
Trippa L
, Aguet F, Stewart C, Dimopoulos MA, Yong K, Bergsagel PL, Manier S,
Getz G
,
Ghobrial IM
. Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression. J Clin Oncol. 2020 07 20; 38(21):2380-2389.
PMID:
32442065
; PMCID:
PMC7367550
.
Citations:
37
Fields:
Neo
Neoplasms
Translation:
Humans
Yu T, Du C, Ma X, Sui W, Yu Z, Liu L, Zhao L, Li Z, Xu J, Wei X, Zhou W, Deng S, Zou D, An G,
Tai YT
, Tricot G,
Anderson KC
, Qiu L, Zhan F, Hao M. Polycomb-like Protein 3 Induces Proliferation and Drug Resistance in Multiple Myeloma and Is Regulated by miRNA-15a. Mol Cancer Res. 2020 07; 18(7):1063-1073.
PMID:
32312841
.
Citations:
12
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Xing L, Lin L, Yu T, Li Y, Cho SF,
Liu J
, Wen K, Hsieh PA, Kinneer K,
Munshi N
,
Anderson KC
,
Tai YT
. A novel BCMA PBD-ADC with ATM/ATR/WEE1 inhibitors or bortezomib induce synergistic lethality in multiple myeloma. Leukemia. 2020 08; 34(8):2150-2162.
PMID:
32060401
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Schmidts A, Ormhøj M,
Choi BD
, Taylor AO, Bouffard AA, Scarfò I, Larson RC,
Frigault MJ
,
Gallagher K
, Castano AP, Riley LS, Cabral ML, Boroughs AC, Velasco Cárdenas RM, Schamel W, Zhou J, Mackay S,
Tai YT
,
Anderson KC
,
Maus MV
. Rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma. Blood Adv. 2019 11 12; 3(21):3248-3260.
PMID:
31698455
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Yan Y, Mao X, Liu J, Fan H, Du C, Li Z, Yi S, Xu Y, Lv R, Liu W, Deng S, Sui W, Wang Q, Zou D, Wang J, Cheng T, Zhan F,
Tai YT
, Yuan C, Du X, Qiu L,
Anderson KC
, An G. The impact of response kinetics for multiple myeloma in the era of novel agents. Blood Adv. 2019 10 08; 3(19):2895-2904.
PMID:
31594763
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
An G, Yan Y, Xu Y, Mao X, Liu J, Fan H, Wang Q, Du C, Li Z, Yi S, Lv R, Deng S, Sui W, Fu M, Hao M, Huang W, Zou D, Zhao Y, Yuan C, Du X, Wang J, Cheng T,
Tai YT
,
Munshi NC
, Qiu L. Monitoring the cytogenetic architecture of minimal residual plasma cells indicates therapy-induced clonal selection in multiple myeloma. Leukemia. 2020 02; 34(2):578-588.
PMID:
31591469
.
Citations:
8
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Ray A
, Song Y,
Du T
,
Tai YT
,
Chauhan D
,
Anderson KC
. Targeting tryptophan catabolic kynurenine pathway enhances antitumor immunity and cytotoxicity in multiple myeloma. Leukemia. 2020 02; 34(2):567-577.
PMID:
31462737
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Maura F, Bolli N, Angelopoulos N, Dawson KJ, Leongamornlert D, Martincorena I, Mitchell TJ, Fullam A, Gonzalez S,
Szalat R
, Abascal F, Rodriguez-Martin B,
Samur MK
,
Glodzik D
, Roncador M,
Fulciniti M
,
Tai YT
, Minvielle S, Magrangeas F, Moreau P, Corradini P,
Anderson KC
, Tubio JMC, Wedge DC, Gerstung M, Avet-Loiseau H,
Munshi N
, Campbell PJ. Genomic landscape and chronological reconstruction of driver events in multiple myeloma. Nat Commun. 2019 08 23; 10(1):3835.
PMID:
31444325
.
Citations:
83
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Tai YT
,
Anderson KC
. B cell maturation antigen (BCMA)-based immunotherapy for multiple myeloma. Expert Opin Biol Ther. 2019 11; 19(11):1143-1156.
PMID:
31277554
.
Citations:
21
Fields:
Bio
Biology
The
Therapeutics
Translation:
Humans
Cells
Ho M, Chen T,
Liu J
, Dowling P,
Hideshima T
, Zhang L,
Morelli E
, Camci-Unal G,
Wu X
,
Tai YT
, Wen K,
Samur M
, Schlossman RL,
Mazitschek R
, Kavanagh EL, Lindsay S, Harada T, McCann A,
Anderson KC
, O'Gorman P,
Bianchi G
. Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling. Leukemia. 2020 01; 34(1):196-209.
PMID:
31142847
.
Citations:
23
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Fabre C, Mimura N, Bobb K, Kong SY, Gorgun G,
Cirstea D
, Hu Y, Minami J, Ohguchi H, Zhang J, Meshulam J,
Carrasco RD
,
Tai YT
,
Richardson PG
,
Hideshima T
,
Anderson KC
. Correction: Dual Inhibition of Canonical and Noncanonical NF-?B Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma. Clin Cancer Res. 2019 May 01; 25(9):2938.
PMID:
31043386
.
Citations:
1
Fields:
Neo
Neoplasms
Cho SF,
Anderson KC
,
Tai YT
. BCMA CAR T-cell therapy arrives for multiple myeloma: a reality. Ann Transl Med. 2018 Dec; 6(Suppl 2):S93.
PMID:
30740414
; PMCID:
PMC6330615
.
Citations:
4
Kinneer K, Flynn M, Thomas SB, Meekin J, Varkey R, Xiao X, Zhong H, Breen S, Hynes PG, Fleming R, Bezabeh B, Chen CT, Wetzel L, Chen R, Dimasi N,
Tai YT
,
Anderson KC
, Herbst R, Howard PW, Hurt EM, Tice DA. Preclinical assessment of an antibody-PBD conjugate that targets BCMA on multiple myeloma and myeloma progenitor cells. Leukemia. 2019 03; 33(3):766-771.
PMID:
30315237
.
Citations:
21
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Bolli N, Maura F, Minvielle S, Gloznik D,
Szalat R
, Fullam A, Martincorena I, Dawson KJ,
Samur MK
, Zamora J, Tarpey P, Davies H,
Fulciniti M
, Shammas MA,
Tai YT
, Magrangeas F, Moreau P, Corradini P,
Anderson K
, Alexandrov L, Wedge DC, Avet-Loiseau H, Campbell P,
Munshi N
. Genomic patterns of progression in smoldering multiple myeloma. Nat Commun. 2018 08 22; 9(1):3363.
PMID:
30135448
; PMCID:
PMC6105687
.
Citations:
81
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Tai YT
, Lin L, Xing L, Cho SF, Yu T, Acharya C, Wen K, Hsieh PA, Dulos J, van Elsas A,
Munshi N
,
Richardson P
,
Anderson KC
. APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications. Leukemia. 2019 02; 33(2):426-438.
PMID:
30135465
; PMCID:
PMC6367000
.
Citations:
30
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Kinneer K, Meekin J, Tiberghien AC,
Tai YT
, Phipps S, Kiefer CM, Rebelatto MC, Dimasi N, Moriarty A, Papadopoulos KP, Sridhar S, Gregson SJ, Wick MJ, Masterson L,
Anderson KC
, Herbst R, Howard PW, Tice DA. SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked Maytansinoid and Pyrrolobenzodiazepine Warheads. Clin Cancer Res. 2018 12 15; 24(24):6570-6582.
PMID:
30131388
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Cho SF,
Anderson KC
,
Tai YT
. Targeting B Cell Maturation Antigen (BCMA) in Multiple Myeloma: Potential Uses of BCMA-Based Immunotherapy. Front Immunol. 2018; 9:1821.
PMID:
30147690
.
Citations:
97
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Tai YT
, Cho SF,
Anderson KC
. Osteoclast Immunosuppressive Effects in Multiple Myeloma: Role of Programmed Cell Death Ligand 1. Front Immunol. 2018; 9:1822.
PMID:
30147691
.
Citations:
17
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Liu J
,
Song T
, Zhou W, Xing L, Wang S, Ho M, Peng Z,
Tai YT
,
Hideshima T
,
Anderson KC
, Cang Y. A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity. Leukemia. 2019 01; 33(1):171-180.
PMID:
30026574
.
Citations:
26
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Bolli N, Biancon G, Moarii M, Gimondi S, Li Y, de Philippis C, Maura F, Sathiaseelan V,
Tai YT
, Mudie L, O'Meara S, Raine K, Teague JW, Butler AP, Carniti C, Gerstung M, Bagratuni T, Kastritis E, Dimopoulos M, Corradini P,
Anderson KC
, Moreau P, Minvielle S, Campbell PJ, Papaemmanuil E, Avet-Loiseau H,
Munshi NC
. Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups. Leukemia. 2018 12; 32(12):2604-2616.
PMID:
29789651
.
Citations:
71
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine TH, Manier S, Mishima Y,
Murakami N
, Bustoros M, Pistofidis RS, Reidy M, Shen YJ,
Rahmat M
, Lukyanchykov P, Karreci ES, Tsukamoto S, Shi J, Takagi S, Huynh D, Sacco A,
Tai YT
, Chesi M, Bergsagel PL, Roccaro AM,
Azzi J
,
Ghobrial IM
. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018 06 01; 128(6):2487-2499.
PMID:
29558366
; PMCID:
PMC5983341
.
Citations:
35
Fields:
Med
Medicine (General)
Translation:
Animals
Cells
Singh I, Lee SH,
Sperling AS
,
Samur MK
,
Tai YT
,
Fulciniti M
,
Munshi NC
, Mayr C, Leslie CS. Widespread intronic polyadenylation diversifies immune cell transcriptomes. Nat Commun. 2018 04 30; 9(1):1716.
PMID:
29712909
.
Citations:
57
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Kurdi AT, Glavey SV, Bezman NA, Jhatakia A,
Guerriero JL
, Manier S, Moschetta M, Mishima Y, Roccaro A, Detappe A, Liu CJ, Sacco A, Huynh D,
Tai YT
, Robbins MD,
Azzi J
,
Ghobrial IM
. Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab. Mol Cancer Ther. 2018 07; 17(7):1454-1463.
PMID:
29654064
; PMCID:
PMC6030488
.
Citations:
28
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Samur MK
, Minvielle S,
Gulla A
,
Fulciniti M
, Cleynen A, Aktas Samur A,
Szalat R
, Shammas M, Magrangeas F,
Tai YT
, Auclair D, Keats J,
Richardson P
, Attal M, Moreau P,
Anderson KC
,
Parmigiani G
, Avet-Loiseau H,
Munshi NC
. Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma. Leukemia. 2018 12; 32(12):2626-2635.
PMID:
29749396
; PMCID:
PMC6163089
.
Citations:
27
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Guo G,
Raje NS
, Seifer C, Kloeber J, Isenhart R, Ha G,
Yee AJ
,
O'Donnell EK
,
Tai YT
,
Richardson PG
,
Bianchi G
,
Laubach JP
, Warren D, Gemme E, Voisine J,
Frede J
, Kokkalis A,
Yun H
,
Dimitrova V
, Vijaykumar T,
Meyerson M
,
Munshi NC
,
Anderson KC
,
Knoechel B
,
Lohr JG
. Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing. Leukemia. 2018 08; 32(8):1838-1841.
PMID:
29749395
; PMCID:
PMC6160352
.
Citations:
22
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Bae J
,
Hideshima T
,
Tai YT
, Song Y,
Richardson P
,
Raje N
,
Munshi NC
,
Anderson KC
. Histone deacetylase (HDAC) inhibitor ACY241 enhances anti-tumor activities of antigen-specific central memory cytotoxic T lymphocytes against multiple myeloma and solid tumors. Leukemia. 2018 09; 32(9):1932-1947.
PMID:
29487385
; PMCID:
PMC6537609
.
Citations:
49
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Tai YT
,
Anderson KC
. Targeting CD38 alleviates tumor-induced immunosuppression. Oncotarget. 2017 Dec 22; 8(68):112166-112167.
PMID:
29348814
.
Citations:
7
Fields:
Neo
Neoplasms
Cho SF, Lin L, Xing L, Yu T, Wen K,
Anderson KC
,
Tai YT
. Monoclonal Antibody: A New Treatment Strategy against Multiple Myeloma. Antibodies (Basel). 2017 Nov 14; 6(4).
PMID:
31548533
; PMCID:
PMC6698817
.
Citations:
6
Zhang L,
Tai YT
, Ho MZG, Qiu L,
Anderson KC
. Interferon-alpha-based immunotherapies in the treatment of B cell-derived hematologic neoplasms in today's treat-to-target era. Exp Hematol Oncol. 2017; 6:20.
PMID:
28725493
; PMCID:
PMC5512936
.
Citations:
13
Yin L, Tagde A, Gali R,
Tai YT
,
Hideshima T
,
Anderson K
,
Avigan D
,
Kufe D
. MUC1-C is a target in lenalidomide resistant multiple myeloma. Br J Haematol. 2017 09; 178(6):914-926.
PMID:
28643330
; PMCID:
PMC5591051
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Sagawa M, Ohguchi H, Harada T,
Samur MK
,
Tai YT
,
Munshi NC
, Kizaki M,
Hideshima T
,
Anderson KC
. Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma. Clin Cancer Res. 2017 Sep 01; 23(17):5225-5237.
PMID:
28442502
; PMCID:
PMC5581671
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Zhang L,
Tai YT
, Ho M, Xing L, Chauhan D, Gang A, Qiu L, Anderson KC. Regulatory B cell-myeloma cell interaction confers immunosuppression and promotes their survival in the bone marrow milieu. Blood Cancer J. 2017 03 24; 7(3):e547.
PMID:
28338671
.
Citations:
41
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Shi L, Qin X, Wang H, Xia Y, Li Y, Chen X, Shang L,
Tai YT
, Feng X, Acharya P, Acharya C, Xu Y, Deng S, Hao M, Zou D, Zhao Y, Ru K, Qiu L, An G. Elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio and decreased platelet-to-lymphocyte ratio are associated with poor prognosis in multiple myeloma. Oncotarget. 2017 Mar 21; 8(12):18792-18801.
PMID:
27852046
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Feng X, Zhang L, Acharya C, An G, Wen K, Qiu L,
Munshi NC
,
Tai YT
,
Anderson KC
. Targeting CD38 Suppresses Induction and Function of T Regulatory Cells to Mitigate Immunosuppression in Multiple Myeloma. Clin Cancer Res. 2017 Aug 01; 23(15):4290-4300.
PMID:
28249894
; PMCID:
PMC5540790
.
Citations:
100
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hideshima T
,
Qi J
, Paranal RM, Tang W, Greenberg E, West N, Colling ME, Estiu G,
Mazitschek R
,
Perry JA
, Ohguchi H, Cottini F, Mimura N, Görgün G,
Tai YT
,
Richardson PG
,
Carrasco RD
, Wiest O, Schreiber SL,
Anderson KC
, Bradner JE. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma. Proc Natl Acad Sci U S A. 2016 11 15; 113(46):13162-13167.
PMID:
27799547
; PMCID:
PMC5135369
.
Citations:
51
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Tai YT
,
Anderson KC
. A new era of immune therapy in multiple myeloma. Blood. 2016 07 21; 128(3):318-9.
PMID:
27445408
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
An G, Acharya C, Feng X, Wen K, Zhong M, Zhang L,
Munshi NC
, Qiu L,
Tai YT
,
Anderson KC
. Osteoclasts promote immune suppressive microenvironment in multiple myeloma: therapeutic implication. Blood. 2016 09 22; 128(12):1590-603.
PMID:
27418644
; PMCID:
PMC5034739
.
Citations:
81
Fields:
Hem
Hematology
Translation:
Humans
Cells
Cea M, Cagnetta A, Acharya C, Acharya P,
Tai YT
, Yang C, Lovera D, Soncini D, Miglino M, Fraternali-Orcioni G, Mastracci L, Nencioni A, Montecucco F, Monacelli F, Ballestrero A,
Hideshima T
,
Chauhan D
, Gobbi M, Lemoli RM,
Munshi N
,
Treon SP
,
Anderson KC
. Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status. Clin Cancer Res. 2016 Dec 15; 22(24):6099-6109.
PMID:
27287071
; PMCID:
PMC5771267
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Lin J, Zhang W, Zhao JJ, Kwart AH, Yang C, Ma D, Ren X,
Tai YT
,
Anderson KC
,
Handin RI
,
Munshi NC
. A clinically relevant in vivo zebrafish model of human multiple myeloma to study preclinical therapeutic efficacy. Blood. 2016 07 14; 128(2):249-52.
PMID:
27207793
; PMCID:
PMC4946203
.
Citations:
28
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Tai YT
, Acharya C, An G, Moschetta M, Zhong MY, Feng X, Cea M, Cagnetta A, Wen K, van Eenennaam H, van Elsas A, Qiu L,
Richardson P
,
Munshi N
,
Anderson KC
. APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment. Blood. 2016 06 23; 127(25):3225-36.
PMID:
27127303
; PMCID:
PMC4920023
.
Citations:
107
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Song Y, Ray A, Li S, Das DS,
Tai YT
,
Carrasco RD
, Chauhan D, Anderson KC. Targeting proteasome ubiquitin receptor Rpn13 in multiple myeloma. Leukemia. 2016 09; 30(9):1877-86.
PMID:
27118409
.
Citations:
36
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Tagde A, Rajabi H, Bouillez A, Alam M, Gali R, Bailey S,
Tai YT
,
Hideshima T
,
Anderson K
,
Avigan D
,
Kufe D
. MUC1-C drives MYC in multiple myeloma. Blood. 2016 05 26; 127(21):2587-97.
PMID:
26907633
; PMCID:
PMC4882805
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
Cells
Eda H, Santo L,
Wein MN
, Hu DZ,
Cirstea DD
, Nemani N,
Tai YT
, Raines SE, Kuhstoss SA,
Munshi NC
,
Kronenberg HM
,
Raje NS
. Regulation of Sclerostin Expression in Multiple Myeloma by Dkk-1: A Potential Therapeutic Strategy for Myeloma Bone Disease. J Bone Miner Res. 2016 06; 31(6):1225-34.
PMID:
26763740
; PMCID:
PMC5002355
.
Citations:
47
Fields:
Met
Metabolism
Ort
Orthopedics
Translation:
Humans
Animals
Cells
Ohguchi H,
Hideshima T
, Bhasin MK, Gorgun GT, Santo L, Cea M,
Samur MK
, Mimura N, Suzuki R,
Tai YT
,
Carrasco RD
,
Raje N
,
Richardson PG
,
Munshi NC
, Harigae H, Sanda T, Sakai J,
Anderson KC
. The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival. Nat Commun. 2016 Jan 05; 7:10258.
PMID:
26728187
.
Citations:
45
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Cea M, Cagnetta A, Adamia S, Acharya C,
Tai YT
,
Fulciniti M
, Ohguchi H, Munshi A, Acharya P, Bhasin MK, Zhong L,
Carrasco R
, Monacelli F, Ballestrero A,
Richardson P
, Gobbi M, Lemoli RM,
Munshi N
,
Hideshima T
, Nencioni A,
Chauhan D
,
Anderson KC
. Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells. Blood. 2016 Mar 03; 127(9):1138-50.
PMID:
26675349
; PMCID:
PMC4778164
.
Citations:
46
Fields:
Hem
Hematology
Translation:
Humans
Cells
Xu L,
Hunter ZR
, Tsakmaklis N,
Cao Y
, Yang G, Chen J, Liu X, Kanan S,
Castillo JJ
,
Tai YT
, Zehnder JL,
Brown JR
,
Carrasco RD
, Advani R, Sabile JM, Argyropoulos K, Lia Palomba M, Morra E, Trojani A, Greco A, Tedeschi A, Varettoni M, Arcaini L, Munshi NM,
Anderson KC
,
Treon SP
. Clonal architecture of CXCR4 WHIM-like mutations in Waldenström Macroglobulinaemia. Br J Haematol. 2016 Mar; 172(5):735-44.
PMID:
26659815
; PMCID:
PMC5409813
.
Citations:
51
Fields:
Hem
Hematology
Translation:
Humans
Suzuki R, Kikuchi S, Harada T, Mimura N, Minami J, Ohguchi H, Yoshida Y, Sagawa M, Gorgun G,
Cirstea D
, Cottini F, Jakubikova J,
Tai YT
,
Chauhan D
,
Richardson PG
,
Munshi N
, Ando K, Utsugi T,
Hideshima T
,
Anderson KC
. Combination of a Selective HSP90a/ß Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells. PLoS One. 2015; 10(12):e0143847.
PMID:
26630652
.
Citations:
9
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Tai YT
,
Anderson KC
. Targeting B-cell maturation antigen in multiple myeloma. Immunotherapy. 2015; 7(11):1187-99.
PMID:
26370838
; PMCID:
PMC4976846
.
Citations:
82
Fields:
All
Allergy and Immunology
The
Therapeutics
Translation:
Humans
Animals
Cells
Jiang H, Acharya C, An G, Zhong M, Feng X, Wang L, Dasilva N, Song Z, Yang G, Adrian F, Qiu L,
Richardson P
,
Munshi NC
,
Tai YT
, Anderson KC. SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide. Leukemia. 2016 Feb; 30(2):399-408.
PMID:
26338273
.
Citations:
78
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Zhao JJ, Chu ZB, Hu Y, Lin J, Wang Z, Jiang M, Chen M, Wang X, Kang Y, Zhou Y, Ni Chonghaile T, Johncilla ME,
Tai YT
, Cheng JQ, Letai A,
Munshi NC
,
Anderson KC
,
Carrasco RD
. Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma. Cancer Res. 2015 Oct 15; 75(20):4384-4397.
PMID:
26249174
; PMCID:
PMC4609291
.
Citations:
43
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Roccaro AM, Mishima Y, Sacco A, Moschetta M,
Tai YT
, Shi J, Zhang Y, Reagan MR, Huynh D, Kawano Y, Sahin I, Chiarini M, Manier S, Cea M, Aljawai Y, Glavey S,
Morgan E
, Pan C,
Michor F
, Cardarelli P, Kuhne M,
Ghobrial IM
. CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation. Cell Rep. 2015 Jul 28; 12(4):622-35.
PMID:
26190113
.
Citations:
62
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Cottini F,
Hideshima T
, Suzuki R,
Tai YT
, Bianchini G,
Richardson PG
,
Anderson KC
, Tonon G. Synthetic Lethal Approaches Exploiting DNA Damage in Aggressive Myeloma. Cancer Discov. 2015 Sep; 5(9):972-87.
PMID:
26080835
.
Citations:
54
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Zhu D, Wang Z, Zhao JJ, Calimeri T, Meng J,
Hideshima T
,
Fulciniti M
, Kang Y,
Ficarro SB
,
Tai YT
,
Hunter Z
, McMilin D, Tong H,
Mitsiades CS
,
Wu CJ
,
Treon SP
,
Dorfman DM
,
Pinkus G
,
Munshi NC
, Tassone P,
Marto JA
,
Anderson KC
,
Carrasco RD
. The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells. Nat Med. 2015 Jun; 21(6):572-80.
PMID:
26005854
; PMCID:
PMC4567046
.
Citations:
38
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Hideshima T, Cottini F, Ohguchi H, Jakubikova J, Gorgun G, Mimura N,
Tai YT
,
Munshi NC
,
Richardson PG
, Anderson KC. Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma. Blood Cancer J. 2015 May 15; 5:e312.
PMID:
25978432
.
Citations:
25
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Görgün G,
Samur MK
, Cowens KB, Paula S,
Bianchi G
, Anderson JE, White RE, Singh A, Ohguchi H, Suzuki R, Kikuchi S, Harada T,
Hideshima T
,
Tai YT
,
Laubach JP
,
Raje N
, Magrangeas F, Minvielle S, Avet-Loiseau H,
Munshi NC
,
Dorfman DM
,
Richardson PG
,
Anderson KC
. Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma. Clin Cancer Res. 2015 Oct 15; 21(20):4607-18.
PMID:
25979485
; PMCID:
PMC4609232
.
Citations:
141
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kikuchi S, Suzuki R, Ohguchi H, Yoshida Y, Lu D, Cottini F, Jakubikova J, Bianchi G, Harada T, Gorgun G,
Tai YT
,
Richardson PG
, Hideshima T, Anderson KC. Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma. Leukemia. 2015 Sep; 29(9):1918-27.
PMID:
25801913
.
Citations:
25
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
An G, Li Z,
Tai YT
, Acharya C, Li Q, Qin X, Yi S, Xu Y, Feng X, Li C, Zhao J, Shi L, Zang M,
Deng S
, Sui W, Hao M, Zou D, Zhao Y, Qi J, Cheng T, Ru K, Wang J,
Anderson KC
, Qiu L. The impact of clone size on the prognostic value of chromosome aberrations by fluorescence in situ hybridization in multiple myeloma. Clin Cancer Res. 2015 May 01; 21(9):2148-56.
PMID:
25652456
.
Citations:
43
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
An G, Acharya C, Deng S, Yi S, Xu Y, Qin X, Sui W, Li Z, Shi L, Zang M, Feng X, Hao M, Zou D, Zhao Y, Qi J, Cheng T, Ru K, Wang J,
Tai YT
, Qiu L. Cytogenetic and clinical marks for defining high-risk myeloma in the context of bortezomib treatment. Exp Hematol. 2015 Mar; 43(3):168-176.e2.
PMID:
25462022
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Suzuki R, Hideshima T, Mimura N, Minami J, Ohguchi H, Kikuchi S, Yoshida Y, Gorgun G,
Cirstea D
, Cottini F, Jakubikova J,
Tai YT
, Chauhan D,
Richardson PG
,
Munshi NC
, Utsugi T, Anderson KC. Anti-tumor activities of selective HSP90a/ß inhibitor, TAS-116, in combination with bortezomib in multiple myeloma. Leukemia. 2015 Feb; 29(2):510-4.
PMID:
25306900
.
Citations:
14
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
An G, Qin X, Acharya C, Xu Y, Deng S, Shi L, Zang M, Sui W, Yi S, Li Z, Hao M, Feng X, Jin F, Zou D, Qi J, Zhao Y,
Tai YT
, Wang J, Qiu L. Multiple myeloma patients with low proportion of circulating plasma cells had similar survival with primary plasma cell leukemia patients. Ann Hematol. 2015 Feb; 94(2):257-64.
PMID:
25231928
.
Citations:
23
Fields:
Hem
Hematology
Translation:
Humans
Cells
Rashid NU,
Sperling AS
, Bolli N, Wedge DC, Van Loo P,
Tai YT
, Shammas MA,
Fulciniti M
,
Samur MK
,
Richardson PG
, Magrangeas F, Minvielle S, Futreal PA,
Anderson KC
, Avet-Loiseau H, Campbell PJ,
Parmigiani G
,
Munshi NC
. Differential and limited expression of mutant alleles in multiple myeloma. Blood. 2014 Nov 13; 124(20):3110-7.
PMID:
25237203
; PMCID:
PMC4231420
.
Citations:
35
Fields:
Hem
Hematology
Translation:
Humans
Zhang Y, Moschetta M, Huynh D,
Tai YT
, Zhang Y, Zhang W, Mishima Y, Ring JE, Tam WF, Xu Q, Maiso P, Reagan M, Sahin I, Sacco A, Manier S, Aljawai Y, Glavey S,
Munshi NC
,
Anderson KC
, Pachter J, Roccaro AM,
Ghobrial IM
. Pyk2 promotes tumor progression in multiple myeloma. Blood. 2014 Oct 23; 124(17):2675-86.
PMID:
25217697
; PMCID:
PMC4208283
.
Citations:
38
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Reagan MR, Mishima Y, Glavey SV, Zhang Y, Manier S, Lu ZN, Memarzadeh M, Zhang Y, Sacco A, Aljawai Y, Shi J,
Tai YT
,
Ready JE
, Kaplan DL, Roccaro AM,
Ghobrial IM
. Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model. Blood. 2014 Nov 20; 124(22):3250-9.
PMID:
25205118
; PMCID:
PMC4239334
.
Citations:
59
Fields:
Hem
Hematology
Translation:
Humans
Cells
Mimura N,
Hideshima T
, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J,
Cirstea D
, Gorgun G, Minami J,
Tai YT
,
Richardson PG
, Utsugi T, Iwama A,
Anderson KC
. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition. Cancer Res. 2014 Aug 15; 74(16):4458-69.
PMID:
24934808
.
Citations:
39
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Zhao JJ, Lin J, Zhu D, Wang X, Brooks D, Chen M, Chu ZB, Takada K,
Ciccarelli B
, Admin S, Tao J,
Tai YT
,
Treon S
,
Pinkus G
, Kuo WP,
Hideshima T
,
Bouxsein M
,
Munshi N
,
Anderson K
,
Carrasco R
. miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/ß-catenin/BCL9 pathway. Cancer Res. 2014 Mar 15; 74(6):1801-13.
PMID:
24599134
.
Citations:
87
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Tai YT
, Mayes PA, Acharya C, Zhong MY, Cea M, Cagnetta A, Craigen J, Yates J, Gliddon L, Fieles W, Hoang B, Tunstead J, Christie AL, Kung AL,
Richardson P
,
Munshi NC
,
Anderson KC
. Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma. Blood. 2014 May 15; 123(20):3128-38.
PMID:
24569262
; PMCID:
PMC4023420
.
Citations:
162
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Laubach JP
,
Tai YT
,
Richardson PG
,
Anderson KC
. Daratumumab granted breakthrough drug status. Expert Opin Investig Drugs. 2014 Apr; 23(4):445-52.
PMID:
24555809
.
Citations:
19
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Bolli N, Avet-Loiseau H, Wedge DC, Van Loo P, Alexandrov LB, Martincorena I, Dawson KJ, Iorio F, Nik-Zainal S, Bignell GR, Hinton JW, Li Y, Tubio JM, McLaren S, O' Meara S, Butler AP, Teague JW, Mudie L, Anderson E, Rashid N,
Tai YT
, Shammas MA,
Sperling AS
,
Fulciniti M
,
Richardson PG
,
Parmigiani G
, Magrangeas F, Minvielle S, Moreau P, Attal M, Facon T, Futreal PA,
Anderson KC
, Campbell PJ,
Munshi NC
. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma. Nat Commun. 2014; 5:2997.
PMID:
24429703
.
Citations:
401
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Tian Z, D'Arcy P, Wang X,
Ray A
,
Tai YT
, Hu Y,
Carrasco RD
,
Richardson P
, Linder S,
Chauhan D
,
Anderson KC
. A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance. Blood. 2014 Jan 30; 123(5):706-16.
PMID:
24319254
; PMCID:
PMC3907756
.
Citations:
161
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Yang G, Zhou Y, Liu X, Xu L,
Cao Y
, Manning RJ, Patterson CJ,
Buhrlage SJ
, Gray N,
Tai YT
,
Anderson KC
,
Hunter ZR
,
Treon SP
. A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia. Blood. 2013 Aug 15; 122(7):1222-32.
PMID:
23836557
.
Citations:
124
Fields:
Hem
Hematology
Translation:
Humans
Cells
Cagnetta A, Cea M, Calimeri T, Acharya C,
Fulciniti M
,
Tai YT
,
Hideshima T
,
Chauhan D
, Zhong MY, Patrone F, Nencioni A, Gobbi M,
Richardson P
,
Munshi N
,
Anderson KC
. Intracellular NAD? depletion enhances bortezomib-induced anti-myeloma activity. Blood. 2013 Aug 15; 122(7):1243-55.
PMID:
23823317
; PMCID:
PMC3744991
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells