Harvard Catalyst Profiles

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Adrian Marino Enriquez, Ph.D., M.D.

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selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Parrack PH, Mariño-Enríquez A, Fletcher CDM, Hornick JL, Papke DJ. GLI1 Immunohistochemistry Distinguishes Mesenchymal Neoplasms With GLI1 Alterations From Morphologic Mimics. Am J Surg Pathol. 2023 04 01; 47(4):453-460. PMID: 36693363.
    Citations:    Fields:    
  2. Schaefer IM, Hemming ML, Lundberg MZ, Serrata MP, Goldaracena I, Liu N, Yin P, Paulo JA, Gygi SP, George S, Morgan JA, Bertagnolli MM, Sicinska ET, Chu C, Zheng S, Mariño-Enríquez A, Hornick JL, Raut CP, Ou WB, Demetri GD, Saka SK, Fletcher JA. Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST. Br J Cancer. 2022 11; 127(11):2072-2085. PMID: 36175617; PMCID: PMC9681737.
    Citations:    Fields:    Translation:Humans
  3. Anderson WJ, Mertens F, Mariño-Enríquez A, Hornick JL, Fletcher CDM. Superficial CD34-Positive Fibroblastic Tumor: A Clinicopathologic, Immunohistochemical, and Molecular Study of 59 Cases. Am J Surg Pathol. 2022 10 01; 46(10):1329-1339. PMID: 35713642.
    Citations:    Fields:    Translation:Humans
  4. Acosta AM, Sholl LM, Marino-Enriquez A, Dal Cin P, Dickson BC, Gordetsky JB, Pins MR, McKenney JK, Fletcher CD. In Response to "Reexamining the molecular findings in specialized stromal tumors of the prostate". Mod Pathol. 2021 11; 34(11):2082-2083. PMID: 34497361.
    Citations:    Fields:    Translation:Humans
  5. Acosta AM, Sholl LM, Dickson BC, McKenney JK, Gordetsky JB, Pins MR, Marino-Enriquez A, Dong F, Dubuc AM, Cin PD, Fletcher CDM. Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecular heterogeneity, including non-recurring gene fusions characteristic of uterine and soft tissue sarcoma subtypes. Mod Pathol. 2021 09; 34(9):1763-1779. PMID: 33986460.
    Citations: 2     Fields:    Translation:Humans
  6. Ou WB, Lundberg MZ, Zhu S, Bahri N, Kyriazoglou A, Xu L, Chen T, Mariño-Enriquez A, Fletcher JA. YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways. Oncogenesis. 2021 May 04; 10(5):37. PMID: 33947829.
    Citations: 1     
  7. Schaefer IM, Lundberg MZ, Demicco EG, Przybyl J, Matusiak M, Chibon F, Ingram DR, Hornick JL, Wang WL, Bauer S, Baker LH, Lazar AJ, van de Rijn M, Mariño-Enríquez A, Fletcher JA. Relationships between highly recurrent tumor suppressor alterations in 489 leiomyosarcomas. Cancer. 2021 08 01; 127(15):2666-2673. PMID: 33788262; PMCID: PMC8277678.
    Citations: 4     Fields:    Translation:Humans
  8. Monjazeb AM, Giobbie-Hurder A, Lako A, Thrash EM, Brennick RC, Kao KZ, Manuszak C, Gentzler RD, Tesfaye A, Jabbour SK, Alese OB, Rahma OE, Cleary JM, Sharon E, Mamon HJ, Cho M, Streicher H, Chen HX, Ahmed MM, Mariño-Enríquez A, Kim-Schulze S, Gnjatic S, Maverakis E, Marusina AI, Merleev AA, Severgnini M, Pfaff KL, Lindsay J, Weirather JL, Ranasinghe S, Spektor A, Rodig SJ, Hodi SF, Schoenfeld JD. A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-Dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer. Clin Cancer Res. 2021 05 01; 27(9):2470-2480. PMID: 33568343; PMCID: PMC8102320.
    Citations: 13     Fields:    Translation:Humans
  9. Wong KS, Mariño-Enriquez A, Hornick JL, Jo VY. NR4A3 Immunohistochemistry Reliably Discriminates Acinic Cell Carcinoma from Mimics. Head Neck Pathol. 2021 Jun; 15(2):425-432. PMID: 32910350.
    Citations: 5     Fields:    Translation:Humans
  10. Atiq MA, Davis JL, Hornick JL, Dickson BC, Fletcher CDM, Fletcher JA, Folpe AL, Mariño-Enríquez A. Mesenchymal tumors of the gastrointestinal tract with NTRK rearrangements: a clinicopathological, immunophenotypic, and molecular study of eight cases, emphasizing their distinction from gastrointestinal stromal tumor (GIST). Mod Pathol. 2021 01; 34(1):95-103. PMID: 32669612.
    Citations: 17     Fields:    Translation:Humans
  11. Hemming ML, Nathenson MJ, Lin JR, Mei S, Du Z, Malik K, Marino-Enriquez A, Jagannathan JP, Sorger PK, Bertagnolli M, Sicinska E, Demetri GD, Santagata S. Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of NTRK1. JCO Precis Oncol. 2020; 4:79-90. PMID: 32133433; PMCID: PMC7055910.
    Citations: 9     Fields:    
  12. Cote GM, Choy E, Chen T, Marino-Enriquez A, Morgan J, Merriam P, Thornton K, Wagner AJ, Nathenson MJ, Demetri G, George S. A phase II multi-strata study of lurbinectedin as a single agent or in combination with conventional chemotherapy in metastatic and/or unresectable sarcomas. Eur J Cancer. 2020 02; 126:21-32. PMID: 31896519.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  13. Huang M, Yang W, Zhu J, Mariño-Enríquez A, Zhu C, Chen J, Wu Y, Quan Y, Qiu H, Li X, Chai L, Fletcher JA, Ou WB. Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours. Br J Cancer. 2020 02; 122(3):372-381. PMID: 31776458; PMCID: PMC7000686.
    Citations: 2     Fields:    Translation:HumansCells
  14. Serrano C, Leal A, Kuang Y, Morgan JA, Barysauskas CM, Phallen J, Triplett O, Mariño-Enríquez A, Wagner AJ, Demetri GD, Velculescu VE, Paweletz CP, Fletcher JA, George S. Phase I Study of Rapid Alternation of Sunitinib and Regorafenib for the Treatment of Tyrosine Kinase Inhibitor Refractory Gastrointestinal Stromal Tumors. Clin Cancer Res. 2019 12 15; 25(24):7287-7293. PMID: 31471313.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  15. Ou WB, Ni N, Zuo R, Zhuang W, Zhu M, Kyriazoglou A, Wu D, Eilers G, Demetri GD, Qiu H, Li B, Marino-Enriquez A, Fletcher JA. Cyclin D1 is a mediator of gastrointestinal stromal tumor KIT-independence. Oncogene. 2019 09; 38(39):6615-6629. PMID: 31371779.
    Citations: 13     Fields:    Translation:Humans
  16. Mühlenberg T, Ketzer J, Heinrich MC, Grunewald S, Marino-Enriquez A, Trautmann M, Hartmann W, Wardelmann E, Treckmann J, Worm K, Bertram S, Herold T, Schildhaus HU, Glimm H, Stenzinger A, Brors B, Horak P, Hohenberger P, Fröhling S, Fletcher JA, Bauer S. KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy. Mol Cancer Ther. 2019 11; 18(11):1985-1996. PMID: 31308077.
    Citations: 11     Fields:    Translation:HumansCells
  17. Yoon JY, Mariño-Enriquez A, Stickle N, de Borja RJ, Ismiil N, Djordjevic B, Virtanen C, Ravat A, Nucci MR, Mirkovic J, Parra-Herran C. Myxoid smooth muscle neoplasia of the uterus: comprehensive analysis by next-generation sequencing and nucleic acid hybridization. Mod Pathol. 2019 11; 32(11):1688-1697. PMID: 31189997.
    Citations: 2     Fields:    Translation:HumansCells
  18. Serrano C, Mariño-Enríquez A, Tao DL, Ketzer J, Eilers G, Zhu M, Yu C, Mannan AM, Rubin BP, Demetri GD, Raut CP, Presnell A, McKinley A, Heinrich MC, Czaplinski JT, Sicinska E, Bauer S, George S, Fletcher JA. Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours. Br J Cancer. 2019 03; 120(6):612-620. PMID: 30792533; PMCID: PMC6462042.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  19. Mito JK, Mitra D, Barysauskas CM, Mariño-Enriquez A, Morgan EA, Fletcher CDM, Raut CP, Baldini EH, Doyle LA. A Comparison of Outcomes and Prognostic Features for Radiation-Associated Angiosarcoma of the Breast and Other Radiation-Associated Sarcomas. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):425-435. PMID: 30703514.
    Citations: 9     Fields:    Translation:Humans
  20. Jo VY, Mariño-Enríquez A, Fletcher CDM, Hornick JL. Expression of PAX3 Distinguishes Biphenotypic Sinonasal Sarcoma From Histologic Mimics. Am J Surg Pathol. 2018 10; 42(10):1275-1285. PMID: 29863547.
    Citations: 12     Fields:    Translation:Humans
  21. Stojanov IJ, Mariño-Enriquez A, Bahri N, Jo VY, Woo SB. Lipomas of the Oral Cavity: Utility of MDM2 and CDK4 in Avoiding Overdiagnosis as Atypical Lipomatous Tumor. Head Neck Pathol. 2019 Jun; 13(2):169-176. PMID: 29748845; PMCID: PMC6513928.
    Citations: 9     Fields:    Translation:Humans
  22. Mariño-Enriquez A, Lauria A, Przybyl J, Ng TL, Kowalewska M, Debiec-Rychter M, Ganesan R, Sumathi V, George S, McCluggage WG, Nucci MR, Lee CH, Fletcher JA. BCOR Internal Tandem Duplication in High-grade Uterine Sarcomas. Am J Surg Pathol. 2018 03; 42(3):335-341. PMID: 29200103.
    Citations: 32     Fields:    Translation:HumansCells
  23. Schaefer IM, Mariño-Enríquez A, Fletcher JA. What is New in Gastrointestinal Stromal Tumor? Adv Anat Pathol. 2017 Sep; 24(5):259-267. PMID: 28632504.
    Citations: 31     Fields:    Translation:HumansCells
  24. Conner JR, Mariño-Enríquez A, Mino-Kenudson M, Garcia E, Pitman MB, Sholl LM, Srivastava A, Doyle LA. Genomic Characterization of Low- and High-Grade Pancreatic Mucinous Cystic Neoplasms Reveals Recurrent KRAS Alterations in "High-Risk" Lesions. Pancreas. 2017 May/Jun; 46(5):665-671. PMID: 28196015.
    Citations: 5     Fields:    Translation:Humans
  25. Schaefer IM, Wang Y, Liang CW, Bahri N, Quattrone A, Doyle L, Mariño-Enríquez A, Lauria A, Zhu M, Debiec-Rychter M, Grunewald S, Hechtman JF, Dufresne A, Antonescu CR, Beadling C, Sicinska ET, van de Rijn M, Demetri GD, Ladanyi M, Corless CL, Heinrich MC, Raut CP, Bauer S, Fletcher JA. MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation. Nat Commun. 2017 03 08; 8:14674. PMID: 28270683; PMCID: PMC5344969.
    Citations: 25     Fields:    Translation:HumansCells
  26. Mariño-Enriquez A, Nascimento AF, Ligon AH, Liang C, Fletcher CD. Atypical Spindle Cell Lipomatous Tumor: Clinicopathologic Characterization of 232 Cases Demonstrating a Morphologic Spectrum. Am J Surg Pathol. 2017 Feb; 41(2):234-244. PMID: 27879515.
    Citations: 28     Fields:    Translation:Humans
  27. Lee JC, Li CF, Huang HY, Zhu MJ, Mariño-Enríquez A, Lee CT, Ou WB, Hornick JL, Fletcher JA. ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma. J Pathol. 2017 Feb; 241(3):316-323. PMID: 27874193.
    Citations: 32     Fields:    Translation:HumansCells
  28. de Jong Y, van Maldegem AM, Marino-Enriquez A, de Jong D, Suijker J, Briaire-de Bruijn IH, Kruisselbrink AB, Cleton-Jansen AM, Szuhai K, Gelderblom H, Fletcher JA, Bovée JV. Inhibition of Bcl-2 family members sensitizes mesenchymal chondrosarcoma to conventional chemotherapy: report on a novel mesenchymal chondrosarcoma cell line. Lab Invest. 2016 10; 96(10):1128-37. PMID: 27617402.
    Citations: 14     Fields:    Translation:HumansCells
  29. Mariño-Enríquez A, Bovée JV. Molecular Pathogenesis and Diagnostic, Prognostic and Predictive Molecular Markers in Sarcoma. Surg Pathol Clin. 2016 Sep; 9(3):457-73. PMID: 27523972.
    Citations: 12     Fields:    Translation:Humans
  30. Falkenhorst J, Grunewald S, Mühlenberg T, Marino-Enriquez A, Reis AC, Corless C, Heinrich M, Treckmann J, Podleska LE, Schuler M, Fletcher JA, Bauer S. Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib. Oncotarget. 2016 Jul 05; 7(27):41390-41403. PMID: 27167336.
    Citations: 13     Fields:    Translation:HumansCells
  31. de Graaff MA, de Rooij MA, van den Akker BE, Gelderblom H, Chibon F, Coindre JM, Marino-Enriquez A, Fletcher JA, Cleton-Jansen AM, Bovée JV. Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy. Br J Cancer. 2016 05 24; 114(11):1219-26. PMID: 27140314; PMCID: PMC4891502.
    Citations: 6     Fields:    Translation:HumansCells
  32. Cajaiba MM, Jennings LJ, Rohan SM, Perez-Atayde AR, Marino-Enriquez A, Fletcher JA, Geller JI, Leuer KM, Bridge JA, Perlman EJ. ALK-rearranged renal cell carcinomas in children. Genes Chromosomes Cancer. 2016 May; 55(5):442-51. PMID: 26773439.
    Citations: 16     Fields:    Translation:Humans
  33. Wong WJ, Wong WJ, Lauria A, Hornick JL, Xiao S, Fletcher JA, Marino-Enriquez A. Alternate PAX3-FOXO1 oncogenic fusion in biphenotypic sinonasal sarcoma. Genes Chromosomes Cancer. 2016 Jan; 55(1):25-9. PMID: 26355893.
    Citations: 22     Fields:    Translation:Humans
  34. Marino-Enriquez A. Advances in the Molecular Analysis of Soft Tissue Tumors and Clinical Implications. Surg Pathol Clin. 2015 Sep; 8(3):525-37. PMID: 26297069.
    Citations:    Fields:    Translation:Humans
  35. Ou WB, Zhu J, Eilers G, Li X, Kuang Y, Liu L, Mariño-Enríquez A, Yan Z, Li H, Meng F, Zhou H, Sheng Q, Fletcher JA. HDACi inhibits liposarcoma via targeting of the MDM2-p53 signaling axis and PTEN, irrespective of p53 mutational status. Oncotarget. 2015 Apr 30; 6(12):10510-20. PMID: 25888633; PMCID: PMC4496371.
    Citations: 20     Fields:    Translation:HumansCells
  36. Doyle LA, Mariño-Enriquez A, Fletcher CD, Hornick JL. ALK rearrangement and overexpression in epithelioid fibrous histiocytoma. Mod Pathol. 2015 Jul; 28(7):904-12. PMID: 25857825.
    Citations: 16     Fields:    Translation:HumansCells
  37. Eilers G, Czaplinski JT, Mayeda M, Bahri N, Tao D, Zhu M, Hornick JL, Lindeman NI, Sicinska E, Wagner AJ, Fletcher JA, Mariño-Enriquez A. CDKN2A/p16 Loss Implicates CDK4 as a Therapeutic Target in Imatinib-Resistant Dermatofibrosarcoma Protuberans. Mol Cancer Ther. 2015 Jun; 14(6):1346-53. PMID: 25852058; PMCID: PMC4458458.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  38. Lee JC, Jeng YM, Su SY, Wu CT, Tsai KS, Lee CH, Lin CY, Carter JM, Huang JW, Chen SH, Shih SR, Mariño-Enríquez A, Chen CC, Folpe AL, Chang YL, Liang CW. Identification of a novel FN1-FGFR1 genetic fusion as a frequent event in phosphaturic mesenchymal tumour. J Pathol. 2015 Mar; 235(4):539-45. PMID: 25319834.
    Citations: 47     Fields:    Translation:Humans
  39. Marino-Enriquez A, Fletcher CD. Shouldn't we care about the biology of benign tumours? Nat Rev Cancer. 2014 11; 14(11):701-2. PMID: 25688395.
    Citations: 9     Fields:    Translation:Humans
  40. Smith NE, Deyrup AT, Mariño-Enriquez A, Fletcher JA, Bridge JA, Illei PB, Netto GJ, Argani P. VCL-ALK renal cell carcinoma in children with sickle-cell trait: the eighth sickle-cell nephropathy? Am J Surg Pathol. 2014 Jun; 38(6):858-63. PMID: 24698962.
    Citations: 26     Fields:    Translation:Humans
  41. Mariño-Enríquez A, Fletcher CD. Round cell sarcomas - biologically important refinements in subclassification. Int J Biochem Cell Biol. 2014 Aug; 53:493-504. PMID: 24801613.
    Citations: 18     Fields:    Translation:Humans
  42. Wang Y, Marino-Enriquez A, Bennett RR, Zhu M, Shen Y, Eilers G, Lee JC, Henze J, Fletcher BS, Gu Z, Fox EA, Antonescu CR, Fletcher CD, Guo X, Raut CP, Demetri GD, van de Rijn M, Ordog T, Kunkel LM, Fletcher JA. Dystrophin is a tumor suppressor in human cancers with myogenic programs. Nat Genet. 2014 Jun; 46(6):601-6. PMID: 24793134.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  43. Maynard MA, Marino-Enriquez A, Fletcher JA, Dorfman DM, Raut CP, Yassa L, Guo C, Wang Y, Dorfman C, Feldman HA, Frates MC, Song H, Jugo RH, Taguchi T, Hershman JM, Larsen PR, Huang SA. Thyroid hormone inactivation in gastrointestinal stromal tumors. N Engl J Med. 2014 Apr 03; 370(14):1327-34. PMID: 24693892; PMCID: PMC4186889.
    Citations: 20     Fields:    Translation:Humans
  44. Serrano C, Wang Y, Mariño-Enríquez A, Lee JC, Ravegnini G, Morgan JA, Bertagnolli MM, Beadling C, Demetri GD, Corless CL, Heinrich MC, Fletcher JA. KRAS and KIT Gatekeeper Mutations Confer Polyclonal Primary Imatinib Resistance in GI Stromal Tumors: Relevance of Concomitant Phosphatidylinositol 3-Kinase/AKT Dysregulation. J Clin Oncol. 2015 Aug 01; 33(22):e93-6. PMID: 24687822; PMCID: PMC4559610.
    Citations: 20     Fields:    Translation:HumansCells
  45. Doyle LA, Tao D, Mariño-Enríquez A. STAT6 is amplified in a subset of dedifferentiated liposarcoma. Mod Pathol. 2014 Sep; 27(9):1231-7. PMID: 24457460.
    Citations: 34     Fields:    Translation:Humans
  46. Mariño-Enríquez A, Hornick JL, Dal Cin P, Cibas ES, Qian X. Dedifferentiated liposarcoma and pleomorphic liposarcoma: a comparative study of cytomorphology and MDM2/CDK4 expression on fine-needle aspiration. Cancer Cytopathol. 2014 Feb; 122(2):128-37. PMID: 24227706.
    Citations: 11     Fields:    Translation:Humans
  47. Lee CH, Hoang LN, Yip S, Reyes C, Marino-Enriquez A, Eilers G, Tao D, Chiang S, Fletcher JA, Soslow RA, Nucci MR, Oliva E. Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement. Mod Pathol. 2014 May; 27(5):751-7. PMID: 24186140.
    Citations: 18     Fields:    Translation:Humans
  48. Mariño-Enríquez A, Dal Cin P. ALK as a paradigm of oncogenic promiscuity: different mechanisms of activation and different fusion partners drive tumors of different lineages. Cancer Genet. 2013 Nov; 206(11):357-73. PMID: 24091028.
    Citations: 26     Fields:    Translation:HumansAnimals
  49. Hodi FS, Corless CL, Giobbie-Hurder A, Fletcher JA, Zhu M, Marino-Enriquez A, Friedlander P, Gonzalez R, Weber JS, Gajewski TF, O'Day SJ, Kim KB, Lawrence D, Flaherty KT, Luke JJ, Collichio FA, Ernstoff MS, Heinrich MC, Beadling C, Zukotynski KA, Yap JT, Van den Abbeele AD, Demetri GD, Fisher DE. Imatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin. J Clin Oncol. 2013 Sep 10; 31(26):3182-90. PMID: 23775962; PMCID: PMC4878082.
    Citations: 185     Fields:    Translation:HumansCTClinical Trials
  50. Mariño-Enríquez A, Ou WB, Cowley G, Luo B, Jonker AH, Mayeda M, Okamoto M, Eilers G, Czaplinski JT, Sicinska E, Wang Y, Taguchi T, Demetri GD, Root DE, Fletcher JA. Genome-wide functional screening identifies CDC37 as a crucial HSP90-cofactor for KIT oncogenic expression in gastrointestinal stromal tumors. Oncogene. 2014 Apr 03; 33(14):1872-6. PMID: 23584476; PMCID: PMC4310725.
    Citations: 14     Fields:    Translation:HumansCells
  51. Ravegnini G, Mariño-Enriquez A, Slater J, Eilers G, Wang Y, Zhu M, Nucci MR, George S, Angelini S, Raut CP, Fletcher JA. MED12 mutations in leiomyosarcoma and extrauterine leiomyoma. Mod Pathol. 2013 May; 26(5):743-9. PMID: 23222489.
    Citations: 37     Fields:    Translation:Humans
  52. Lee CH, Ali RH, Rouzbahman M, Marino-Enriquez A, Zhu M, Guo X, Brunner AL, Chiang S, Leung S, Nelnyk N, Huntsman DG, Blake Gilks C, Nielsen TO, Dal Cin P, van de Rijn M, Oliva E, Fletcher JA, Nucci MR. Cyclin D1 as a diagnostic immunomarker for endometrial stromal sarcoma with YWHAE-FAM22 rearrangement. Am J Surg Pathol. 2012 Oct; 36(10):1562-70. PMID: 22982899; PMCID: PMC3444748.
    Citations: 35     Fields:    Translation:HumansCells
  53. Chen BJ, Mariño-Enríquez A, Fletcher CD, Hornick JL. Loss of retinoblastoma protein expression in spindle cell/pleomorphic lipomas and cytogenetically related tumors: an immunohistochemical study with diagnostic implications. Am J Surg Pathol. 2012 Aug; 36(8):1119-28. PMID: 22790852.
    Citations: 33     Fields:    Translation:Humans
  54. Heinrich MC, Marino-Enriquez A, Presnell A, Donsky RS, Griffith DJ, McKinley A, Patterson J, Taguchi T, Liang CW, Fletcher JA. Sorafenib inhibits many kinase mutations associated with drug-resistant gastrointestinal stromal tumors. Mol Cancer Ther. 2012 Aug; 11(8):1770-80. PMID: 22665524.
    Citations: 35     Fields:    Translation:HumansCells
  55. Lee CH, Mariño-Enriquez A, Ou W, Zhu M, Ali RH, Chiang S, Amant F, Gilks CB, van de Rijn M, Oliva E, Debiec-Rychter M, Dal Cin P, Fletcher JA, Nucci MR. The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor. Am J Surg Pathol. 2012 May; 36(5):641-53. PMID: 22456610.
    Citations: 59     Fields:    Translation:Humans
  56. Mariño-Enríquez A, Fletcher CD. Angiofibroma of soft tissue: clinicopathologic characterization of a distinctive benign fibrovascular neoplasm in a series of 37 cases. Am J Surg Pathol. 2012 Apr; 36(4):500-8. PMID: 22301504.
    Citations: 22     Fields:    Translation:HumansCells
  57. Jin Y, Möller E, Nord KH, Mandahl N, Von Steyern FV, Domanski HA, Mariño-Enríquez A, Magnusson L, Nilsson J, Sciot R, Fletcher CD, Debiec-Rychter M, Mertens F. Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes. Genes Chromosomes Cancer. 2012 May; 51(5):510-20. PMID: 22337624.
    Citations: 36     Fields:    Translation:HumansCells
  58. Lee CH, Ou WB, Mariño-Enriquez A, Zhu M, Mayeda M, Wang Y, Guo X, Brunner AL, Amant F, French CA, West RB, McAlpine JN, Gilks CB, Yaffe MB, Prentice LM, McPherson A, Jones SJ, Marra MA, Shah SP, van de Rijn M, Huntsman DG, Dal Cin P, Debiec-Rychter M, Nucci MR, Fletcher JA. 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma. Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3):929-34. PMID: 22223660.
    Citations: 73     Fields:    Translation:HumansCells
  59. Liang CW, Lee YS, Marino-Enriquez A, Tsui K, Huang SH. The utility and limitation of single nucleotide polymorphism analysis on whole genome amplified mesenchymal tumour DNA in formalin fixed tumour samples. Pathology. 2012 Jan; 44(1):33-41. PMID: 22157688.
    Citations: 3     Fields:    Translation:Humans
  60. Jo VY, Mariño-Enríquez A, Fletcher CD. Epithelioid rhabdomyosarcoma: clinicopathologic analysis of 16 cases of a morphologically distinct variant of rhabdomyosarcoma. Am J Surg Pathol. 2011 Oct; 35(10):1523-30. PMID: 21921782.
    Citations: 13     Fields:    Translation:HumansCells
  61. Gutierrez A, Snyder EL, Marino-Enriquez A, Zhang YX, Sioletic S, Kozakewich E, Grebliunaite R, Ou WB, Sicinska E, Raut CP, Demetri GD, Perez-Atayde AR, Wagner AJ, Fletcher JA, Fletcher CD, Look AT. Aberrant AKT activation drives well-differentiated liposarcoma. Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39):16386-91. PMID: 21930930; PMCID: PMC3182699.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  62. Mariño-Enríquez A, Wang WL, Roy A, Lopez-Terrada D, Lazar AJ, Fletcher CD, Coffin CM, Hornick JL. Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. Am J Surg Pathol. 2011 Jan; 35(1):135-44. PMID: 21164297.
    Citations: 83     Fields:    Translation:HumansCells
  63. Liang CW, Mariño-Enríquez A, Johannessen C, Hornick JL, Dal Cin P. Translocation (Y;12) in lipoma. Cancer Genet. 2011 Jan; 204(1):53-6. PMID: 21356192.
    Citations: 1     Fields:    Translation:HumansCells
  64. Mariño-Enríquez A, Ou WB, Weldon CB, Fletcher JA, Pérez-Atayde AR. ALK rearrangement in sickle cell trait-associated renal medullary carcinoma. Genes Chromosomes Cancer. 2011 Mar; 50(3):146-53. PMID: 21213368.
    Citations: 52     Fields:    Translation:Humans
  65. Elco CP, Mariño-Enríquez A, Abraham JA, Dal Cin P, Hornick JL. Hybrid myxoinflammatory fibroblastic sarcoma/hemosiderotic fibrolipomatous tumor: report of a case providing further evidence for a pathogenetic link. Am J Surg Pathol. 2010 Nov; 34(11):1723-7. PMID: 20871391.
    Citations: 12     Fields:    Translation:HumansCells
  66. Mariño-Enríquez A, Fletcher CD, Dal Cin P, Hornick JL. Dedifferentiated liposarcoma with "homologous" lipoblastic (pleomorphic liposarcoma-like) differentiation: clinicopathologic and molecular analysis of a series suggesting revised diagnostic criteria. Am J Surg Pathol. 2010 Aug; 34(8):1122-31. PMID: 20588177.
    Citations: 25     Fields:    Translation:HumansCells
  67. Gwin K, Mariño-Enríquez A, Martel M, Reyes-Múgica M. Sclerosing stromal tumor: an important differential diagnosis of ovarian neoplasms in childhood and adolescence. Pediatr Dev Pathol. 2009 Sep-Oct; 12(5):366-70. PMID: 19071970.
    Citations: 2     Fields:    Translation:Humans
  68. Sendagorta E, Herranz P, Feito M, Ramírez P, Feltes R, Floristán U, Mariño-Enriquez A, Casado M. Lichenoid drug eruption related to imatinib: report of a new case and review of the literature. Clin Exp Dermatol. 2009 Oct; 34(7):e315-6. PMID: 19456782.
    Citations: 2     Fields:    Translation:Humans
  69. Mendiola M, Barriuso J, Mariño-Enríquez A, Redondo A, Domínguez-Cáceres A, Hernández-Cortés G, Pérez-Fernández E, Sánchez-Navarro I, Vara JA, Suárez A, Espinosa E, González-Barón M, Palacios J, Hardisson D. Aurora kinases as prognostic biomarkers in ovarian carcinoma. Hum Pathol. 2009 May; 40(5):631-8. PMID: 19157502.
    Citations: 17     Fields:    Translation:Humans
  70. Mendiola M, Barriuso J, Redondo A, Mariño-Enríquez A, Madero R, Espinosa E, Vara JA, Sánchez-Navarro I, Hernández-Cortes G, Zamora P, Pérez-Fernández E, Miguel-Martín M, Suárez A, Palacios J, González-Barón M, Hardisson D. Angiogenesis-related gene expression profile with independent prognostic value in advanced ovarian carcinoma. PLoS One. 2008; 3(12):e4051. PMID: 19112514.
    Citations: 10     Fields:    Translation:Humans
  71. Viana-Tejedor A, Mariño-Enríquez A, Sánchez-Recalde A, López-Sendón JL. Intimal sarcoma of the pulmonary artery: diagnostic value of different imaging techniques. Rev Esp Cardiol. 2008 Dec; 61(12):1363-5. PMID: 19080983.
    Citations: 5     Fields:    Translation:Humans
  72. Mariño-Enríquez A, Lapunzina P, Omeñaca F, Morales C, Rodríguez JI. Laurin-Sandrow syndrome: review and redefinition. Am J Med Genet A. 2008 Oct 01; 146A(19):2557-65. PMID: 18792985.
    Citations: 2     Fields:    Translation:Humans
  73. Feito-Rodríguez M, García-Macarrón J, Pagán-Muñoz B, Mariño-Enríquez A, Vidaurrázaga-Díaz Y Arcaya C, Díaz-Díaz RM, Casado-Jiménez M. [Disseminated nodular primary localized cutaneous amyloidosis]. Actas Dermosifiliogr. 2008 Oct; 99(8):648-52. PMID: 19080897.
    Citations: 1     Fields:    Translation:Humans
  74. Hardisson D, Regojo RM, Mariño-Enríquez A, Martínez-García M. Signet-ring stromal tumor of the ovary: report of a case and review of the literature. Pathol Oncol Res. 2008 Sep; 14(3):333-6. PMID: 18758997.
    Citations: 4     Fields:    Translation:HumansCells
  75. Mariño-Enríquez A, Li P, Samuelson J, Rossi MR, Reyes-Múgica M. Congenital fibrosarcoma with a novel complex 3-way translocation t(12;15;19) and unusual histologic features. Hum Pathol. 2008 Dec; 39(12):1844-8. PMID: 18657299.
    Citations: 3     Fields:    Translation:HumansCells
  76. Mariño-Enríquez A, González-Rocha T, Burgos E, Stolnicu S, Mendiola M, Nogales FF, Hardisson D. Transitional cell carcinoma of the endometrium and endometrial carcinoma with transitional cell differentiation: a clinicopathologic study of 5 cases and review of the literature. Hum Pathol. 2008 Nov; 39(11):1606-13. PMID: 18620731.
    Citations: 3     Fields:    Translation:Humans
  77. Jimenez-Heffernan JA, Lopez-Ferrer P, Vicandi B, Mariño A, Tejerina E, Nistal M, Viguer JM. Fine-needle aspiration cytology of large cell neuroendocrine carcinoma of the lung: a cytohistologic correlation study of 11 cases. Cancer. 2008 Jun 25; 114(3):180-6. PMID: 18433011.
    Citations: 3     Fields:    Translation:Humans
  78. Nistal M, Garcia-Fernández E, Mariño-Enríquez A, Serrano A, Regadera J, González-Peramato P. [Diagnostic value of the gonadal biopsy in the disorders of sex development]. Actas Urol Esp. 2007 Oct; 31(9):1056-75. PMID: 18257373.
    Citations: 2     Fields:    Translation:Humans
  79. Rodríguez JI, Mariño-Enríquez A, Suárez-Aguado J, Lapunzina P. Umbilical cord stricture is not a genetic anomaly: a study in twins. Pediatr Dev Pathol. 2008 Sep-Oct; 11(5):363-9. PMID: 19006425.
    Citations:    Fields:    Translation:HumansCells
  80. Guerra-Gutiérrez F, Torres Sánchez I, Gallardo-Madueño G, Mariño-Enríquez A, Nistal M, Nistral M. [Pulmonary sclerosing hemangioma in a patient with Cowden syndrome]. Arch Bronconeumol. 2007 Jul; 43(7):418-20. PMID: 17663895.
    Citations: 1     Fields:    Translation:Humans
  81. Nistal M, Mariño-Enríquez A, De Miguel MP. Granular changes (Paneth cell-like) in epididymal epithelial cells are lysosomal in nature and are not markers of obstruction. Histopathology. 2007 Jun; 50(7):944-7. PMID: 17543086.
    Citations: 1     Fields:    Translation:HumansCells
  82. Mariño-Enríquez A, Lapunzina P, Robertson SP, Rodríguez JI. Otopalatodigital syndrome type 2 in two siblings with a novel filamin A 629G>T mutation: clinical, pathological, and molecular findings. Am J Med Genet A. 2007 May 15; 143A(10):1120-5. PMID: 17431908.
    Citations: 4     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.