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Roweth HG, Battinelli EM. Platelets and (Lymph)angiogenesis. Cold Spring Harb Perspect Med. 2023 Jan 03; 13(1).
PMID: 35534208; PMCID: PMC9808548.
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Guo Q, Malloy MW, Roweth HG, McAllister SS, Italiano JE, Battinelli EM. Platelets upregulate tumor cell programmed death ligand 1 in an epidermal growth factor receptor-dependent manner in vitro. Blood Adv. 2022 10 25; 6(20):5668-5675.
PMID: 35482455; PMCID: PMC9582587.
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Citations: Fields:
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AnimalsCells
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Citations: Fields:
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HumansCells
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Lucas F, Stecker MS, Pozdnyakova O, Connors JM, Battinelli EM. Rivaroxaban-calibrated chromogenic anti-Xa assay in cirrhosis: Use to rule out disseminated intravascular coagulation. Res Pract Thromb Haemost. 2021 Oct; 5(7):e12594.
PMID: 34646974.
Citations:
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Gawelek KL, Battinelli EM. Are Platelets SARS-CoV-2's "Dead End"? Circ Res. 2021 09 03; 129(6):647-649.
PMID: 34473529.
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HumansCells
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Tsai FD, Battinelli EM. Inherited Platelet Disorders. Hematol Oncol Clin North Am. 2021 12; 35(6):1069-1084.
PMID: 34391603.
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HumansCells
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Alba GA, Samokhin AO, Wang RS, Zhang YY, Wertheim BM, Arons E, Greenfield EA, Lundberg Slingsby MH, Ceglowski JR, Haley KJ, Bowman FP, Yu YR, Haney JC, Eng G, Mitchell RN, Sheets A, Vargas SO, Seo S, Channick RN, Leary PJ, Rajagopal S, Loscalzo J, Battinelli EM, Maron BA. NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. Am J Respir Crit Care Med. 2021 06 15; 203(12):1533-1545.
PMID: 33523764; PMCID: PMC8483217.
Citations:
5 Fields:
Translation:
HumansAnimalsCells
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Roweth HG, Battinelli EM. Lessons to learn from tumor-educated platelets. Blood. 2021 06 10; 137(23):3174-3180.
PMID: 33940594.
Citations:
8 Fields:
Translation:
HumansAnimalsCells
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Moll M, Zon RL, Sylvester KW, Rimsans J, Chen EC, Ghosh AJ, Abston E, Kim A, Rutherford H, Mitre X, Hakim A, Connell NT, Battinelli E, Fredenburgh LE, Baron RM, Hobbs BD, Cho MH, Mittleman MA, Woolley AE, Connors JM. Intermediate versus standard dose heparin prophylaxis in COVID-19 ICU patients: A propensity score-matched analysis. Thromb Res. 2021 07; 203:57-60.
PMID: 33940309; PMCID: PMC8053596.
Citations:
2 Fields:
Translation:
HumansCells
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Citations:
13 Fields:
Translation:
HumansCells
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Battinelli EM. COVID-19 concerns aggregate around platelets. Blood. 2020 09 10; 136(11):1221-1223.
PMID: 32957116; PMCID: PMC7483434.
Citations:
5 Fields:
Translation:
HumansCellsPHPublic Health
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Citations:
2 Fields:
Translation:
HumansCells
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Citations:
2 Fields:
Translation:
Humans
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Citations:
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Battinelli EM, Thon JN, Okazaki R, Peters CG, Vijey P, Wilkie AR, Noetzli LJ, Flaumenhaft R, Italiano JE. Megakaryocytes package contents into separate a-granules that are differentially distributed in platelets. Blood Adv. 2019 10 22; 3(20):3092-3098.
PMID: 31648331; PMCID: PMC6849942.
Citations:
16 Fields:
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HumansAnimalsCells
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Hall KT, Buring JE, Mukamal KJ, Vinayaga Moorthy M, Wayne PM, Kaptchuk TJ, Battinelli EM, Ridker PM, Sesso HD, Weinstein SJ, Albanes D, Cook NR, Chasman DI. COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials. J Natl Cancer Inst. 2019 07 01; 111(7):684-694.
PMID: 30624689.
Citations:
8 Fields:
Translation:
Humans
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Johnson KE, Ceglowski JR, Roweth HG, Forward JA, Tippy MD, El-Husayni S, Kulenthirarajan R, Malloy MW, Machlus KR, Chen WY, Italiano JE, Battinelli EM. Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis. Blood Adv. 2019 01 22; 3(2):198-211.
PMID: 30670536; PMCID: PMC6341186.
Citations:
17 Fields:
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HumansCells
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Simmons DP, Herskovits AZ, Battinelli EM, Schur PH, Lemire SJ, Dorfman DM. Lupus anticoagulant testing using two parallel methods detects additional cases and predicts persistent positivity. Clin Chem Lab Med. 2018 07 26; 56(8):1289-1296.
PMID: 27305702.
Citations:
2 Fields:
Translation:
Humans
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Takagi S, Tsukamoto S, Park J, Johnson KE, Kawano Y, Moschetta M, Liu CJ, Mishima Y, Kokubun K, Manier S, Salem KZ, Huynh D, Sacco A, Forward J, Roccaro AM, Battinelli EM, Ghobrial IM. Platelets Enhance Multiple Myeloma Progression via IL-1ß Upregulation. Clin Cancer Res. 2018 05 15; 24(10):2430-2439.
PMID: 29440174.
Citations:
17 Fields:
Translation:
HumansAnimalsCells
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Machlus KR, Battinelli EM. RBCs pin platelets against the (thrombus) wall. Blood. 2017 05 04; 129(18):2460-2461.
PMID: 28473411.
Citations:
1 Fields:
Translation:
HumansCells
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Johnson KE, Forward JA, Tippy MD, Ceglowski JR, El-Husayni S, Kulenthirarajan R, Machlus KR, Mayer EL, Italiano JE, Battinelli EM. Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis. Arterioscler Thromb Vasc Biol. 2017 04; 37(4):664-674.
PMID: 28153880; PMCID: PMC5364056.
Citations:
22 Fields:
Translation:
HumansCells
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Hollenhorst MA, Battinelli EM. Thrombosis, Hypercoagulable States, and Anticoagulants. Prim Care. 2016 Dec; 43(4):619-635.
PMID: 27866581.
Citations:
3 Fields:
Translation:
Humans
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Machlus KR, Johnson KE, Kulenthirarajan R, Forward JA, Tippy MD, Soussou TS, El-Husayni SH, Wu SK, Wang S, Watnick RS, Italiano JE, Battinelli EM. CCL5 derived from platelets increases megakaryocyte proplatelet formation. Blood. 2016 Feb 18; 127(7):921-6.
PMID: 26647394; PMCID: PMC4760093.
Citations:
31 Fields:
Translation:
HumansAnimalsCells
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Battinelli EM. Procoagulant Platelets: Not Just Full of Hot Air. Circulation. 2015 Oct 13; 132(15):1374-6.
PMID: 26330410.
Citations:
2 Fields:
Translation:
HumansAnimalsCells
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Battinelli EM. TTP and pregnancy. Blood. 2014 Mar 13; 123(11):1624-5.
PMID: 24627517.
Citations:
1 Fields:
Translation:
Humans
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Battinelli EM, Marshall A, Connors JM. The role of thrombophilia in pregnancy. Thrombosis. 2013; 2013:516420.
PMID: 24455235.
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Battinelli EM, Markens BA, Kulenthirarajan RA, Machlus KR, Flaumenhaft R, Italiano JE. Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response. Blood. 2014 Jan 02; 123(1):101-12.
PMID: 24065244; PMCID: PMC3879901.
Citations:
41 Fields:
Translation:
HumansCells
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Kuznetsov HS, Marsh T, Markens BA, Castaño Z, Greene-Colozzi A, Hay SA, Brown VE, Richardson AL, Signoretti S, Battinelli EM, McAllister SS. Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells. Cancer Discov. 2012 Dec; 2(12):1150-65.
PMID: 22896036.
Citations:
63 Fields:
Translation:
HumansAnimalsCells
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Battinelli EM, Murphy DL, Connors JM. Venous thromboembolism overview. Hematol Oncol Clin North Am. 2012 Apr; 26(2):345-67, ix.
PMID: 22463831.
Citations:
4 Fields:
Translation:
Humans
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Battinelli EM. Reversal of new oral anticoagulants. Circulation. 2011 Oct 04; 124(14):1508-10.
PMID: 21969317.
Citations:
9 Fields:
Translation:
Humans
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Battinelli EM, Markens BA, Italiano JE. Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis. Blood. 2011 Aug 04; 118(5):1359-69.
PMID: 21680800; PMCID: PMC3152500.
Citations:
125 Fields:
Translation:
HumansCells
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Battinelli EM, Bauer KA. Thrombophilias in pregnancy. Hematol Oncol Clin North Am. 2011 Apr; 25(2):323-33, viii.
PMID: 21444033.
Citations:
2 Fields:
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Humans
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Italiano JE, Battinelli EM. Selective sorting of alpha-granule proteins. J Thromb Haemost. 2009 Jul; 7 Suppl 1:173-6.
PMID: 19630794.
Citations:
33 Fields:
Translation:
HumansCells
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Flaumenhaft R, Dilks JR, Richardson J, Alden E, Patel-Hett SR, Battinelli E, Klement GL, Sola-Visner M, Italiano JE. Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles. Blood. 2009 Jan 29; 113(5):1112-21.
PMID: 18802008; PMCID: PMC2635076.
Citations:
109 Fields:
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HumansAnimalsCells
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Italiano JE, Richardson JL, Patel-Hett S, Battinelli E, Zaslavsky A, Short S, Ryeom S, Folkman J, Klement GL. Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released. Blood. 2008 Feb 01; 111(3):1227-33.
PMID: 17962514; PMCID: PMC2214735.
Citations:
296 Fields:
Translation:
HumansCells
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Battinelli EM, Hartwig JH, Italiano JE. Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis. Curr Opin Hematol. 2007 Sep; 14(5):419-26.
PMID: 17934346.
Citations:
26 Fields:
Translation:
HumansAnimalsCells
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Battinelli, E.M. and Garnick, M.B. Complications of Chemotherapy for Urologic Cancer. Complications of Urologic Surgery and Practice K. Loughlin. 2007; 513.
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Battinelli EM, Ansell J. Cancer and thrombosis. Curr Hematol Rep. 2005 Sep; 4(5):378-84.
PMID: 16131439.
Citations:
1 Fields:
Translation:
Humans
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Loscalzo, J. and Battinelli, E.M. Compositions and Methods for Producing Platelets and/or Proplatelets from Megakaryocytes. 2003.
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Battinelli E, Willoughby SR, Foxall T, Valeri CR, Loscalzo J. Induction of platelet formation from megakaryocytoid cells by nitric oxide. Proc Natl Acad Sci U S A. 2001 Dec 04; 98(25):14458-63.
PMID: 11734646; PMCID: PMC64703.
Citations:
20 Fields:
Translation:
HumansAnimalsCells
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Battinelli E, Loscalzo J. Nitric oxide induces apoptosis in megakaryocytic cell lines. Blood. 2000 Jun 01; 95(11):3451-9.
PMID: 10828028.
Citations:
17 Fields:
Translation:
HumansCells
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Battinelli, E.M. and Loscalzo, J. Nitric Oxide and Platelet-Derived Hemostasis. Nitric Oxide and the Cardiovascular System. J. Loscalzo and J. Vita. 2000; 123.
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Freedman JE, Sauter R, Battinelli EM, Ault K, Knowles C, Huang PL, Loscalzo J. Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. Circ Res. 1999 Jun 25; 84(12):1416-21.
PMID: 10381894.
Citations:
60 Fields:
Translation:
AnimalsCells
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Zhang, Y-Y, Prystupa, J., Battinelli, E.M., Loscalzo, J. Suppression of Human Pulmonary Artery Endothelial Cell Growth by 5-Lipoxygenase Inhibitors. Circulation. 1999; 100:I-1253.
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Battinelli, E.M. The Role of Nitric Oxide in Megakaryocyte Apoptosis and Thrombopoiesis. 1999.
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Battinelli, E.M., and Loscalzo, J. . Nitric Oxide Induces Platelet Formation from Megakaryocytes. Circulation. 1999; 100:I-3221.
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Battinelli, E.M., Trolliet, M.R., and Loscalzo, J. . Nitric Oxide and its role in hemostasis. The Pathophysiology and Clinical Applications of Nitric Oxide. G. Rubanyi,. 1998; 229.
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Battinelli, E.M., and Loscalzo, J. . Growth and maturation factors modulate nitric oxide-induced apoptosis in megakaryocytes. Circulation. 1998; 98:I-522.
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Freedman, J., Sauter, R., Battinelli, E., Ault, K., Knowles, C., Huang, P.L., and Loscalzo, J. . Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOS3 gene. Circulation. 1998; 98:I-4.
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Battinelli, E.M., and Loscalzo, J. Nitric oxide induces apoptosis in human megakaryocytes. Circulation. 1997; 96:I-724.
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Battinelli EM, Boyd Y, Craig IW, Breakefield XO, Chen ZY. Characterization and mapping of the mouse NDP (Norrie disease) locus (Ndp). Mamm Genome. 1996 Feb; 7(2):93-7.
PMID: 8835523.
Citations:
1 Fields:
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HumansAnimalsCells
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Battinelli, E.M., Breakefield, X.O., and Chen, Z-Y . Characterization of the mouse NDP (Norrie disease ) locus. American Journal of Human Genetics. 1995; 747.
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Bergen, A-A.B., Berger, W., Chen Z-Y., Diergaarde, P., Battinelli, E.M., Warburg, M., Bleeker-Wagemakers, L.M., Ropers, H-H., and Craig, I.W. . Norrie disease. Molecular Genetics of Inherited Eye Disorders. AF Wright and B. Jay. 1994; 321.
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Schuback, D.E., Adams, J.C., Chen, Z-Y., Battinelli, E.M., Craig, I.W., Corey, D.P., Breakefield, X.O., and Sims, K. . Identification of mutations in the Norrie Disease Gene and Further Elucidation of the Norrie location and function. American Journal of Human Genetics. 1994; 665.
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Chen, Z-Y., Kramm, C.M., Battinelli, E.M., Li, F., Schuback, D.E., and Corey, D.P. . Neuron-specific expression of the Norrie Disease Gene (NDP) in the Central Nervous System. American Journal of Human Genetics. 1994; 747.
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Chen ZY, Battinelli EM, Fielder A, Bundey S, Sims K, Breakefield XO, Craig IW. A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy. Nat Genet. 1993 Oct; 5(2):180-3.
PMID: 8252044.
Citations:
95 Fields:
Translation:
HumansCells
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Chen ZY, Battinelli EM, Woodruff G, Young I, Breakefield XO, Craig IW. Characterization of a mutation within the NDP gene in a family with a manifesting female carrier. Hum Mol Genet. 1993 Oct; 2(10):1727-9.
PMID: 8268931.
Citations:
6 Fields:
Translation:
HumansCells
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Chen ZY, Battinelli EM, Hendriks RW, Powell JF, Middleton-Price H, Sims KB, Breakefield XO, Craig IW. Norrie disease gene: characterization of deletions and possible function. Genomics. 1993 May; 16(2):533-5.
PMID: 8314592.
Citations:
10 Fields:
Translation:
HumansAnimalsCells
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Chen, Z-Y., Battinelli, E.M., Fielder, A., Bundey, S., Sims, K.B., Breakefield, X.O., and Craig, I.W. . Identification of a mutation in the Norrie Disease Gene (NDP) in affected members of a family with X-linked Familial Exudative Vitreoretinopathy. American Journal of Human Genetics. 1993; 1140.
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Battinelli, E.M. Molecular Characterisation of the Norrie Disease Gene. 1992.
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Battinelli, E.M. Characterization of the RNA Splicing Pattern of psbA in the chloroplast of Chlamydomonas reinhardtii. 1991.