I am a physician-scientist trained in Pulmonary and Critical Care Medicine and Genetic Epidemiology. I am an Associate Physician in the Channing Division of Network Medicine at Brigham and Women's Hospital (BWH) and an Associate Professor at Harvard Medical School. My research uses the tools of clinical epidemiology, genetics, and genomics to understand chronic obstructive pulmonary disease (COPD) phenotypes and treatment responses, moving towards personalized medicine for this heterogeneous disease. I am the Principal Investigator of several ancillary studies to the COPDGene Study, funded by the National Heart, Lung and Blood Institute (NHLBI), and I am the co-director of the COPDGene Clinical Center at BWH. My clinical practice focuses on COPD and emphysema, including the overlap between COPD and asthma, as well as Alpha-1 Antitrypsin Deficiency, a genetic form of COPD.