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Feng Yao, Ph.D.


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  1. R56AI093738 (YAO, FENG) Sep 26, 2011 - Aug 31, 2013
    Novel dominant-negative HSV-2 recombinant viral vaccines
    Role: Principal Investigator
  2. R01AI050880 (YAO, FENG) Dec 1, 2003 - Nov 30, 2008
    Self-limiting, and Dominant-negative Herpes Simplex Virus Recombinants
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Akhrameyeva NV, Zhang P, Sugiyama N, Behar SM, Yao F. Development of a glycoprotein D-expressing dominant-negative and replication-defective herpes simplex virus 2 (HSV-2) recombinant viral vaccine against HSV-2 infection in mice. J Virol. 2011 May; 85(10):5036-47. PMID: 21389121.
    Citations: 15     Fields:    Translation:AnimalsCells
  2. Koyama T, Hackl F, Aflaki P, Bergmann J, Zuhaili B, Waisbren E, Govindarajulu U, Yao F, Eriksson E. A new technique of ex vivo gene delivery of VEGF to wounds using genetically modified skin particles promotes wound angiogenesis. J Am Coll Surg. 2011 Mar; 212(3):340-8. PMID: 21247781; PMCID: PMC3050114.
    Citations: 4     Fields:    Translation:Animals
  3. Xu XM, Wang YS, Chen RY, Feng CL, Yao F, Tong SS, Wang L, Yamashita F, Yu JN. Formulation and pharmacokinetic evaluation of tetracycline-loaded solid lipid nanoparticles for subcutaneous injection in mice. Chem Pharm Bull (Tokyo). 2011; 59(2):260-5. PMID: 21297309.
    Citations: 6     Fields:    Translation:Animals
  4. Brans R, Yao F. Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigs. BMC Microbiol. 2010 Jun 03; 10:163. PMID: 20525279.
    Citations: 13     Fields:    Translation:AnimalsCells
  5. Yao F, Murakami N, Bleiziffer O, Zhang P, Akhrameyeva NV, Xu X, Brans R. Development of a regulatable oncolytic herpes simplex virus type 1 recombinant virus for tumor therapy. J Virol. 2010 Aug; 84(16):8163-71. PMID: 20519407.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Reish RG, Zuhaili B, Bergmann J, Aflaki P, Koyama T, Hackl F, Waisbren E, Canseco JA, Verma KD, Eriksson E, Yao F. Modulation of scarring in a liquid environment in the Yorkshire pig. Wound Repair Regen. 2009 Nov-Dec; 17(6):806-16. PMID: 19903302.
    Citations: 8     Fields:    Translation:Animals
  7. Brans R, Akhrameyeva NV, Yao F. Prevention of genital herpes simplex virus type 1 and 2 disease in mice immunized with a gD-expressing dominant-negative recombinant HSV-1. J Invest Dermatol. 2009 Oct; 129(10):2470-9. PMID: 19357711.
    Citations: 11     Fields:    Translation:AnimalsCells
  8. Hirsch T, Spielmann M, Zuhaili B, Fossum M, Metzig M, Koehler T, Steinau HU, Yao F, Onderdonk AB, Steinstraesser L, Eriksson E. Human beta-defensin-3 promotes wound healing in infected diabetic wounds. J Gene Med. 2009 Mar; 11(3):220-8. PMID: 19115333.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  9. Lu Z, Brans R, Akhrameyeva NV, Murakami N, Xu X, Yao F. High-level expression of glycoprotein D by a dominant-negative HSV-1 virus augments its efficacy as a vaccine against HSV-1 infection. J Invest Dermatol. 2009 May; 129(5):1174-84. PMID: 19005489.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  10. Hirsch T, Spielmann M, Velander P, Zuhaili B, Bleiziffer O, Fossum M, Steinstraesser L, Yao F, Eriksson E. Insulin-like growth factor-1 gene therapy and cell transplantation in diabetic wounds. J Gene Med. 2008 Nov; 10(11):1247-52. PMID: 18767030.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  11. Brans R, Eriksson E, Yao F. Immunization with a dominant-negative recombinant HSV type 1 protects against HSV-1 skin disease in guinea pigs. J Invest Dermatol. 2008 Dec; 128(12):2825-32. PMID: 18496565.
    Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
  12. Velander P, Theopold C, Hirsch T, Bleiziffer O, Zuhaili B, Fossum M, Hoeller D, Gheerardyn R, Chen M, Visovatti S, Svensson H, Yao F, Eriksson E. Impaired wound healing in an acute diabetic pig model and the effects of local hyperglycemia. Wound Repair Regen. 2008 Mar-Apr; 16(2):288-93. PMID: 18318812.
    Citations: 25     Fields:    Translation:Animals
  13. Hirsch T, Spielmann M, Zuhaili B, Koehler T, Fossum M, Steinau HU, Yao F, Steinstraesser L, Onderdonk AB, Eriksson E. Enhanced susceptibility to infections in a diabetic wound healing model. BMC Surg. 2008 Feb 29; 8:5. PMID: 18312623.
    Citations: 25     Fields:    Translation:Animals
  14. Vranckx JJ, Hoeller D, Velander PE, Theopold CF, Petrie N, Takedo A, Eriksson E, Yao F. Cell suspension cultures of allogenic keratinocytes are efficient carriers for ex vivo gene transfer and accelerate the healing of full-thickness skin wounds by overexpression of human epidermal growth factor. Wound Repair Regen. 2007 Sep-Oct; 15(5):657-64. PMID: 17971011.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  15. Bleiziffer O, Eriksson E, Yao F, Horch RE, Kneser U. Gene transfer strategies in tissue engineering. J Cell Mol Med. 2007 Mar-Apr; 11(2):206-23. PMID: 17488473; PMCID: PMC3822823.
    Citations: 29     Fields:    Translation:HumansAnimals
  16. Yao F, Pomahac B, Visovatti S, Chen M, Johnson S, Augustinova H, Svensjo T, Eriksson E. Systemic and localized reversible regulation of transgene expression by tetracycline with tetR-mediated transcription repression switch. J Surg Res. 2007 Apr; 138(2):267-74. PMID: 17254606.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  17. Hirsch T, Spielmann M, Yao F, Eriksson E. Gene therapy in cutaneous wound healing. Front Biosci. 2007 Jan 01; 12:2507-18. PMID: 17127259.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  18. Yao F, Theopold C, Hoeller D, Bleiziffer O, Lu Z. Highly efficient regulation of gene expression by tetracycline in a replication-defective herpes simplex viral vector. Mol Ther. 2006 Jun; 13(6):1133-41. PMID: 16574491.
    Citations: 13     Fields:    Translation:AnimalsCells
  19. Petrie NC, Vranckx JJ, Hoeller D, Yao F, Eriksson E. Gene delivery of PDGF for wound healing therapy. J Tissue Viability. 2005 Nov; 15(4):16-21. PMID: 16302501.
    Citations: 1     Fields:    Translation:HumansAnimals
  20. Vranckx JJ, Yao F, Petrie N, Augustinova H, Hoeller D, Visovatti S, Slama J, Eriksson E. In vivo gene delivery of Ad-VEGF121 to full-thickness wounds in aged pigs results in high levels of VEGF expression but not in accelerated healing. Wound Repair Regen. 2005 Jan-Feb; 13(1):51-60. PMID: 15659036.
    Citations: 14     Fields:    Translation:AnimalsCells
  21. Augustinova H, Hoeller D, Yao F. The dominant-negative herpes simplex virus type 1 (HSV-1) recombinant CJ83193 can serve as an effective vaccine against wild-type HSV-1 infection in mice. J Virol. 2004 Jun; 78(11):5756-65. PMID: 15140973; PMCID: PMC415800.
    Citations: 12     Fields:    Translation:AnimalsCellsPHPublic Health
  22. Theopold C, Yao F, Eriksson E. Gene therapy in the treatment of lower extremity wounds. Int J Low Extrem Wounds. 2004 Jun; 3(2):69-79. PMID: 15866792.
    Citations: 1     Fields:    
  23. Petrie NC, Yao F, Eriksson E. Gene therapy in wound healing. Surg Clin North Am. 2003 Jun; 83(3):597-616, vii. PMID: 12822728.
    Citations: 6     Fields:    Translation:Humans
  24. Svensjö T, Yao F, Pomahac B, Winkler T, Eriksson E. Cultured autologous fibroblasts augment epidermal repair. Transplantation. 2002 Apr 15; 73(7):1033-41. PMID: 11965028.
    Citations: 8     Fields:    Translation:AnimalsCells
  25. Svensjö T, Pomahac B, Yao F, Slama J, Wasif N, Eriksson E. Autologous skin transplantation: comparison of minced skin to other techniques. J Surg Res. 2002 Mar; 103(1):19-29. PMID: 11855913.
    Citations: 15     Fields:    Translation:AnimalsCells
  26. Yao F, Eriksson E. Inhibition of herpes simplex virus type 2 (HSV-2) viral replication by the dominant negative mutant polypeptide of HSV-1 origin binding protein. Antiviral Res. 2002 Feb; 53(2):127-33. PMID: 11750938.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  27. Hoeller D, Petrie N, Yao F, Eriksson E. Gene therapy in soft tissue reconstruction. Cells Tissues Organs. 2002; 172(2):118-25. PMID: 12426488.
    Citations: 1     Fields:    Translation:Humans
  28. Yao F, Visovatti S, Johnson CS, Chen M, Slama J, Wenger A, Eriksson E. Age and growth factors in porcine full-thickness wound healing. Wound Repair Regen. 2001 Sep-Oct; 9(5):371-7. PMID: 11896980.
    Citations: 11     Fields:    Translation:Animals
  29. Ogueta SB, Yao F, Marasco WA. Design and in vitro characterization of a single regulatory module for efficient control of gene expression in both plasmid DNA and a self-inactivating lentiviral vector. Mol Med. 2001 Aug; 7(8):569-79. PMID: 11591893; PMCID: PMC1950063.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  30. Svensjö T, Yao F, Pomahac B, Eriksson E. Autologous keratinocyte suspensions accelerate epidermal wound healing in pigs. J Surg Res. 2001 Aug; 99(2):211-21. PMID: 11469889.
    Citations: 12     Fields:    Translation:AnimalsCells
  31. Yao F, Eriksson E. Gene therapy in wound repair and regeneration. Wound Repair Regen. 2000 Nov-Dec; 8(6):443-51. PMID: 11208171.
    Citations: 9     Fields:    Translation:Humans
  32. Svensjö T, Pomahac B, Yao F, Slama J, Eriksson E. Accelerated healing of full-thickness skin wounds in a wet environment. Plast Reconstr Surg. 2000 Sep; 106(3):602-12; discussion 613-4. PMID: 10987467.
    Citations: 39     Fields:    Translation:AnimalsCells
  33. Yao F, Eriksson E. A novel anti-herpes simplex virus type 1-specific herpes simplex virus type 1 recombinant. Hum Gene Ther. 1999 Jul 20; 10(11):1811-8. PMID: 10446921.
    Citations: 13     Fields:    Translation:AnimalsCells
  34. Yao F, Eriksson E. A novel tetracycline-inducible viral replication switch. Hum Gene Ther. 1999 Feb 10; 10(3):419-27. PMID: 10048394.
    Citations: 10     Fields:    Translation:AnimalsCells
  35. Yao F, Svensjö T, Winkler T, Lu M, Eriksson C, Eriksson E. Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells. Hum Gene Ther. 1998 Sep 01; 9(13):1939-50. PMID: 9741432.
    Citations: 91     Fields:    Translation:HumansAnimalsCells
  36. Eriksson E, Yao F, Svensjö T, Winkler T, Slama J, Macklin MD, Andree C, McGregor M, Hinshaw V, Swain WF. In vivo gene transfer to skin and wound by microseeding. J Surg Res. 1998 Aug; 78(2):85-91. PMID: 9733623.
    Citations: 26     Fields:    Translation:AnimalsCellsPHPublic Health
  37. Pomahac B, Svensjö T, Yao F, Brown H, Eriksson E. Tissue engineering of skin. Crit Rev Oral Biol Med. 1998; 9(3):333-44. PMID: 9715370.
    Citations: 12     Fields:    Translation:HumansCells
  38. Silver K, Walston J, Chung WK, Yao F, Parikh VV, Andersen R, Cheskin LJ, Elahi D, Muller D, Leibel RL, Shuldiner AR. The Gln223Arg and Lys656Asn polymorphisms in the human leptin receptor do not associate with traits related to obesity. Diabetes. 1997 Nov; 46(11):1898-900. PMID: 9356043.
    Citations: 8     Fields:    Translation:Humans
  39. Yao F, Schaffer PA. Physical interaction between the herpes simplex virus type 1 immediate-early regulatory proteins ICP0 and ICP4. J Virol. 1994 Dec; 68(12):8158-68. PMID: 7966607; PMCID: PMC237281.
    Citations: 39     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.