Harvard Catalyst Profiles

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Aranya Bagchi, M.B.,B.S.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 20IPA35360009 (Bagchi, Aranya) Jan 1, 2021 - Dec 31, 2022
    American Heart Association
    Using Electrical Impedance Tomography to Study Pulmonary Vascular Distensibility in Patients with Heart Failure
    Role: Principal Investigator
  2. R01DK125786 (Leaf, David E.) Sep 1, 2020 - Jun 30, 2025
    Deferoxamine for the Prevention of Acute Kidney Injury
    Role: Co-Investigator
  3. W81XWH-17-1-0058 (Bagchi, Aranya) May 15, 2017 - May 14, 2019
    Department of Defense - Peer Reviewed Medical Research Program, Discovery Award
    Manipulating the Macrophage Iron-Hepcidin Axis to Prevent Acute Lung Injury/Acute Respiratory Distress Syndrome Secondary to Severe Trauma and Hemorrhagic Shock
    Role: Principal Investigator
  4. (Bagchi, Aranya) Jul 1, 2013 - Jun 30, 2016
    Foundation for Anesthesia Education and Research (FAER)
    Modulation of the Bone Morphogenetic Protein – Hepcidin axis can Reduce the severity of Acute Inflammation and Lung Injury
    Role Description: This project seeks to define the role of intracellular labile iron in monocytes/macrophages in the pathogenesis of post traumatic acute lung injury
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Goto S, Grange RMH, Pinciroli R, Rosales IA, Li R, Boerboom SL, Ostrom KF, Marutani E, Wanderley HV, Bagchi A, Colvin RB, Berra L, Minaeva O, Goldstein LE, Malhotra R, Zapol WM, Ichinose F, Yu B. Electronic cigarette vaping with aged coils causes acute lung injury in mice. Arch Toxicol. 2022 12; 96(12):3363-3371. PMID: 36195745.
    Citations:    Fields:    Translation:Animals
  2. Rashid A, Zeng C, Motta-Ribeiro G, Dillon ST, Libermann TA, Lessa MA, Bagchi A, Hutchinson J, Vidal Melo MF. Proteomics of lung tissue reveals differences in inflammation and alveolar-capillary barrier response between atelectasis and aerated regions. Sci Rep. 2022 04 29; 12(1):7065. PMID: 35487970; PMCID: PMC9053128.
    Citations:    Fields:    Translation:Humans
  3. Traeger L, Wiegand SB, Sauer AJ, Corman BHP, Peneyra KM, Wunderer F, Fischbach A, Bagchi A, Malhotra R, Zapol WM, Bloch DB. UBA6 and NDFIP1 regulate the degradation of ferroportin. Haematologica. 2022 02 01; 107(2):478-488. PMID: 34320783; PMCID: PMC8804582.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Fischbach A, Wiegand SB, Zazzeron L, Traeger L, di Fenza R, Bagchi A, Farinelli WA, Franco W, Korupolu S, Arens J, Grassi L, Zadek F, Bloch DB, Rox Anderson R, Zapol WM. Veno-venous extracorporeal blood phototherapy increases the rate of carbon monoxide (CO) elimination in CO-poisoned pigs. Lasers Surg Med. 2022 02; 54(2):256-267. PMID: 34350599.
    Citations:    Fields:    Translation:HumansAnimals
  5. Zadek F, Rubin J, Grassi L, Van Den Kroonenberg D, Larson G, Capriles M, De Santis Santiago R, Florio G, Imber DA, Bittner EA, Hibbert KA, Legassey A, LaRocque J, Cudemus-Deseda G, Bagchi A, Crowley J, Shelton K, Kacmarek R, Berra L. Individualized Multimodal Physiologic Approach to Mechanical Ventilation in Patients With Obesity and Severe Acute Respiratory Distress Syndrome Reduced Venovenous Extracorporeal Membrane Oxygenation Utilization. Crit Care Explor. 2021 Jul; 3(7):e0461. PMID: 34235455.
  6. Florio G, De Santis Santiago RR, Fumagalli J, Imber DA, Marrazzo F, Sonny A, Bagchi A, Fitch AK, Anekwe CV, Amato MBP, Arora P, Kacmarek RM, Berra L. Pleural Pressure Targeted Positive Airway Pressure Improves Cardiopulmonary Function in Spontaneously Breathing Patients With Obesity. Chest. 2021 06; 159(6):2373-2383. PMID: 34099131; PMCID: PMC8579318.
    Citations:    Fields:    Translation:Humans
  7. Short SAP, Gupta S, Brenner SK, Hayek SS, Srivastava A, Shaefi S, Singh H, Wu B, Bagchi A, Al-Samkari H, Dy R, Wilkinson K, Zakai NA, Leaf DE. d-dimer and Death in Critically Ill Patients With Coronavirus Disease 2019. Crit Care Med. 2021 05 01; 49(5):e500-e511. PMID: 33591017; PMCID: PMC8275993.
    Citations: 13     Fields:    Translation:HumansCells
  8. Grange RMH, Sharma R, Shah H, Reinstadler B, Goldberger O, Cooper MK, Nakagawa A, Miyazaki Y, Hindle AG, Batten AJ, Wojtkiewicz GR, Schleifer G, Bagchi A, Marutani E, Malhotra R, Bloch DB, Ichinose F, Mootha VK, Zapol WM. Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome. Mol Genet Metab. 2021 05; 133(1):83-93. PMID: 33752971; PMCID: PMC8489256.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  9. De Santis Santiago R, Teggia Droghi M, Fumagalli J, Marrazzo F, Florio G, Grassi LG, Gomes S, Morais CCA, Ramos OPS, Bottiroli M, Pinciroli R, Imber DA, Bagchi A, Shelton K, Sonny A, Bittner EA, Amato MBP, Kacmarek RM, Berra L. High Pleural Pressure Prevents Alveolar Overdistension and Hemodynamic Collapse in Acute Respiratory Distress Syndrome with Class III Obesity. A Clinical Trial. Am J Respir Crit Care Med. 2021 03 01; 203(5):575-584. PMID: 32876469; PMCID: PMC7924574.
    Citations: 13     Fields:    Translation:HumansAnimalsCTClinical Trials
  10. Shaefi S, Shankar P, Mueller AL, O'Gara BP, Spear K, Khabbaz KR, Bagchi A, Chu LM, Banner-Goodspeed V, Leaf DE, Talmor DS, Marcantonio ER, Subramaniam B. Intraoperative Oxygen Concentration and Neurocognition after Cardiac Surgery. Anesthesiology. 2021 02 01; 134(2):189-201. PMID: 33331902; PMCID: PMC7855826.
    Citations: 3     Fields:    Translation:Humans
  11. Ataya A, Silverman EP, Bagchi A, Sarwal A, Criner GJ, McDonagh DL. Temporary Transvenous Diaphragmatic Neurostimulation in Prolonged Mechanically Ventilated Patients: A Feasibility Trial (RESCUE 1). Crit Care Explor. 2020 Apr; 2(4):e0106. PMID: 32426748; PMCID: PMC7188416.
    Citations: 2     
  12. Florio G, Ferrari M, Bittner EA, De Santis Santiago R, Pirrone M, Fumagalli J, Teggia Droghi M, Mietto C, Pinciroli R, Berg S, Bagchi A, Shelton K, Kuo A, Lai Y, Sonny A, Lai P, Hibbert K, Kwo J, Pino RM, Wiener-Kronish J, Amato MBP, Arora P, Kacmarek RM, Berra L. A lung rescue team improves survival in obesity with acute respiratory distress syndrome. Crit Care. 2020 01 15; 24(1):4. PMID: 31937345; PMCID: PMC6961369.
    Citations: 14     Fields:    Translation:Humans
  13. Malhotra R, Mauer AC, Lino Cardenas CL, Guo X, Yao J, Zhang X, Wunderer F, Smith AV, Wong Q, Pechlivanis S, Hwang SJ, Wang J, Lu L, Nicholson CJ, Shelton G, Buswell MD, Barnes HJ, Sigurslid HH, Slocum C, Rourke CO, Rhee DK, Bagchi A, Nigwekar SU, Buys ES, Campbell CY, Harris T, Budoff M, Criqui MH, Rotter JI, Johnson AD, Song C, Franceschini N, Debette S, Hoffmann U, Kälsch H, Nöthen MM, Sigurdsson S, Freedman BI, Bowden DW, Jöckel KH, Moebus S, Erbel R, Feitosa MF, Gudnason V, Thanassoulis G, Zapol WM, Lindsay ME, Bloch DB, Post WS, O'Donnell CJ. HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. Nat Genet. 2019 11; 51(11):1580-1587. PMID: 31659325; PMCID: PMC6858575.
    Citations: 28     Fields:    Translation:HumansAnimals
  14. Hayashida K, Bagchi A, Miyazaki Y, Hirai S, Seth D, Silverman MG, Rezoagli E, Marutani E, Mori N, Magliocca A, Liu X, Berra L, Hindle AG, Donnino MW, Malhotra R, Bradley MO, Stamler JS, Ichinose F. Improvement in Outcomes After Cardiac Arrest and Resuscitation by Inhibition of S-Nitrosoglutathione Reductase. Circulation. 2019 02 05; 139(6):815-827. PMID: 30586713; PMCID: PMC6361681.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  15. Malhotra R, Wunderer F, Barnes HJ, Bagchi A, Buswell MD, O'Rourke CD, Slocum CL, Ledsky CD, Peneyra KM, Sigurslid H, Corman B, Johansson KB, Rhee DK, Bloch KD, Bloch DB. Hepcidin Deficiency Protects Against Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019 02; 39(2):178-187. PMID: 30587002; PMCID: PMC6344241.
    Citations: 18     Fields:    Translation:AnimalsCells
  16. Bagchi A, Batten AJ, Levin M, Allen KN, Fitzgerald ML, Hückstädt LA, Costa DP, Buys ES, Hindle AG. Intrinsic anti-inflammatory properties in the serum of two species of deep-diving seal. J Exp Biol. 2018 07 09; 221(Pt 13). PMID: 29748216.
    Citations: 7     Fields:    Translation:AnimalsCells
  17. Bagchi A, Vidal Melo MF. Follow the Voxel-A New Method for the Analysis of Regional Strain in Lung Injury. Crit Care Med. 2018 06; 46(6):1033-1035. PMID: 29762413; PMCID: PMC6103789.
    Citations: 1     Fields:    Translation:Animals
  18. Vandenwijngaert S, Ledsky CD, Agha O, Wu C, Hu D, Bagchi A, Domian IJ, Buys ES, Newton-Cheh C, Bloch DB. MicroRNA-425 and microRNA-155 cooperatively regulate atrial natriuretic peptide expression and cGMP production. PLoS One. 2018; 13(4):e0196697. PMID: 29698509.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  19. Bagchi A, Rudolph MI, Eikermann M. Mechanical ventilation mode and postoperative pulmonary complications - a reply. Anaesthesia. 2018 02; 73(2):253-254. PMID: 29333710.
    Citations:    Fields:    Translation:Humans
  20. Bagchi A, Rudolph MI, Ng PY, Timm FP, Long DR, Shaefi S, Ladha K, Vidal Melo MF, Eikermann M. The association of postoperative pulmonary complications in 109,360 patients with pressure-controlled or volume-controlled ventilation. Anaesthesia. 2017 Nov; 72(11):1334-1343. PMID: 28891046; PMCID: PMC6696935.
    Citations: 14     Fields:    Translation:Humans
  21. Hoeft K, Bloch DB, Graw JA, Malhotra R, Ichinose F, Bagchi A. Iron Loading Exaggerates the Inflammatory Response to the Toll-like Receptor 4 Ligand Lipopolysaccharide by Altering Mitochondrial Homeostasis. Anesthesiology. 2017 07; 127(1):121-135. PMID: 28430694; PMCID: PMC5478432.
    Citations: 12     Fields:    Translation:AnimalsCells
  22. Ma IWY, Caplin JD, Azad A, Wilson C, Fifer MA, Bagchi A, Liteplo AS, Noble VE. Correlation of carotid blood flow and corrected carotid flow time with invasive cardiac output measurements. Crit Ultrasound J. 2017 Dec; 9(1):10. PMID: 28429291; PMCID: PMC5398973.
    Citations: 15     
  23. O'Rourke C, Shelton G, Hutcheson JD, Burke MF, Martyn T, Thayer TE, Shakartzi HR, Buswell MD, Tainsh RE, Yu B, Bagchi A, Rhee DK, Wu C, Derwall M, Buys ES, Yu PB, Bloch KD, Aikawa E, Bloch DB, Malhotra R. Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation. J Vis Exp. 2016 05 31; (111). PMID: 27284788.
    Citations: 8     Fields:    Translation:HumansAnimals
  24. Ikeda K, Liu X, Kida K, Marutani E, Hirai S, Sakaguchi M, Andersen LW, Bagchi A, Cocchi MN, Berg KM, Ichinose F, Donnino MW. Thiamine as a neuroprotective agent after cardiac arrest. Resuscitation. 2016 08; 105:138-44. PMID: 27185216.
    Citations: 18     Fields:    Translation:HumansAnimals
  25. Bagchi A, Eikermann M. Mashed potatoes and maize: are the starches safe? Anesthesiology. 2013 Feb; 118(2):244-7. PMID: 23340348.
    Citations: 1     Fields:    Translation:Animals
  26. Baron DM, Yu B, Lei C, Bagchi A, Beloiartsev A, Stowell CP, Steinbicker AU, Malhotra R, Bloch KD, Zapol WM. Pulmonary hypertension in lambs transfused with stored blood is prevented by breathing nitric oxide. Anesthesiology. 2012 Mar; 116(3):637-47. PMID: 22293717; PMCID: PMC3293704.
    Citations: 32     Fields:    Translation:Animals
  27. Shin HS, Xu F, Bagchi A, Herrup E, Prakash A, Valentine C, Kulkarni H, Wilhelmsen K, Warren S, Hellman J. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. J Immunol. 2011 Jan 15; 186(2):1119-30. PMID: 21169547; PMCID: PMC3482611.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  28. Meier A, Bagchi A, Sidhu HK, Alter G, Suscovich TJ, Kavanagh DG, Streeck H, Brockman MA, LeGall S, Hellman J, Altfeld M. Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands. AIDS. 2008 Mar 12; 22(5):655-8. PMID: 18317010; PMCID: PMC2810187.
    Citations: 51     Fields:    Translation:HumansCells
  29. Petersen B, Bloch KD, Ichinose F, Shin HS, Shigematsu M, Bagchi A, Zapol WM, Hellman J. Activation of Toll-like receptor 2 impairs hypoxic pulmonary vasoconstriction in mice. Am J Physiol Lung Cell Mol Physiol. 2008 Feb; 294(2):L300-8. PMID: 18055842.
    Citations: 10     Fields:    Translation:AnimalsCells
  30. Meier A, Alter G, Frahm N, Sidhu H, Li B, Bagchi A, Teigen N, Streeck H, Stellbrink HJ, Hellman J, van Lunzen J, Altfeld M. MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands. J Virol. 2007 Aug; 81(15):8180-91. PMID: 17507480; PMCID: PMC1951290.
    Citations: 136     Fields:    Translation:HumansAnimalsCells
  31. Zhu X, Bagchi A, Zhao H, Kirschning CJ, Hajjar RJ, Chao W, Hellman J, Schmidt U. Toll-like receptor 2 activation by bacterial peptidoglycan-associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction. Crit Care Med. 2007 Mar; 35(3):886-92. PMID: 17255871.
    Citations: 35     Fields:    Translation:AnimalsCells
  32. Bagchi A, Herrup EA, Warren HS, Trigilio J, Shin HS, Valentine C, Hellman J. MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. J Immunol. 2007 Jan 15; 178(2):1164-71. PMID: 17202381.
    Citations: 148     Fields:    Translation:AnimalsCells
  33. Valentine CH, Hellman J, Beasley-Topliffe LK, Bagchi A, Warren HS. Passive immunization to outer membrane proteins MLP and PAL does not protect mice from sepsis. Mol Med. 2006 Sep-Oct; 12(9-10):252-8. PMID: 17225874; PMCID: PMC1770012.
    Citations: 4     Fields:    Translation:HumansAnimals
  34. Liang MD, Bagchi A, Warren HS, Tehan MM, Trigilio JA, Beasley-Topliffe LK, Tesini BL, Lazzaroni JC, Fenton MJ, Hellman J. Bacterial peptidoglycan-associated lipoprotein: a naturally occurring toll-like receptor 2 agonist that is shed into serum and has synergy with lipopolysaccharide. J Infect Dis. 2005 Mar 15; 191(6):939-48. PMID: 15717270.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  35. Puri GD, Bagchi A, Anandamurthy B, Dhaliwal RS. The Bispectral Index and induced hypothermia--electrocerebral silence at an unusually high temperature. Anaesth Intensive Care. 2003 Oct; 31(5):578-80. PMID: 14601285.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.