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Joshua Robert Mauney, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK119240 (MAUNEY, JOSHUA ROBERT) Dec 18, 2019 - Apr 30, 2024
    NIH/NIDDK
    Partial Bladder Outlet Obstruction: Mechanisms of Injury and Novel Repair Strategies
    Role: Principal Investigator
  2. R01DK107568 (MAUNEY, JOSHUA ROBERT) Oct 12, 2019 - Jun 30, 2021
    NIH/NIDDK
    Development of Silk Fibroin Grafts for Reconstruction of Esophageal Defects
    Role: Co-Principal Investigator
  3. R21EB021482 (MAUNEY, JOSHUA ROBERT) Mar 3, 2016 - Dec 31, 2018
    NIH/NIBIB
    Instructive Biomaterial Designs for Urethroplasty
    Role: Co-Principal Investigator
  4. R21EB020860 (MAUNEY, JOSHUA ROBERT) Jul 6, 2015 - Jun 30, 2017
    NIH/NIBIB
    Development of Silk Fibroin Grafts for Reconstruction of Pathological Bladders
    Role: Co-Principal Investigator
  5. R00DK083616 (MAUNEY, JOSHUA ROBERT) Sep 1, 2012 - Jul 31, 2015
    NIH/NIDDK
    Novel Strategies in Bladder Tissue Engineering: Stem Cells and Silk Biomaterials
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gundogdu G, Morhardt D, Cristofaro V, Algarrahi K, Yang X, Costa K, Galvez Alegria C, Sullivan MP, Mauney JR. Evaluation of Bilayer Silk Fibroin Grafts for Tubular Esophagoplasty in a Porcine Defect Model. Tissue Eng Part A. 2020 Jun 26. PMID: 32460641.
    Citations:    
  2. Affas S, Schäfer FM, Algarrahi K, Cristofaro V, Sullivan MP, Yang X, Costa K, Sack B, Gharaee-Kermani M, Macoska JA, Gundogdu G, Seager C, Estrada CR, Mauney JR. Augmentation Cystoplasty of Diseased Porcine Bladders with Bi-Layer Silk Fibroin Grafts. Tissue Eng Part A. 2019 06; 25(11-12):855-866. PMID: 30191762.
    Citations:    Fields:    
  3. Galvez Alegria C, Gundogdu G, Yang X, Costa K, Mauney JR. Evaluation of Acellular Bilayer Silk Fibroin Grafts for Onlay Tracheoplasty in a Rat Defect Model. Otolaryngol Head Neck Surg. 2019 02; 160(2):310-319. PMID: 30274546.
    Citations:    Fields:    
  4. Algarrahi K, Affas S, Sack BS, Yang X, Costa K, Seager C, Estrada CR, Mauney JR. Repair of injured urethras with silk fibroin scaffolds in a rabbit model of onlay urethroplasty. J Surg Res. 2018 09; 229:192-199. PMID: 29936989.
    Citations:    Fields:    
  5. Schäfer FM, Algarrahi K, Savarino A, Yang X, Seager C, Franck D, Costa K, Liu S, Logvinenko T, Adam R, Mauney JR. Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair. Stem Cell Reports. 2017 12 12; 9(6):2005-2017. PMID: 29173895.
    Citations:    Fields:    Translation:HumansAnimals
  6. Algarrahi K, Franck D, Savarino A, Cristofaro V, Yang X, Affas S, Schäfer FM, Sullivan MP, Estrada CR, Mauney JR. Bilayer silk fibroin grafts support functional oesophageal repair in a rodent model of caustic injury. J Tissue Eng Regen Med. 2018 02; 12(2):e1068-e1075. PMID: 28371514.
    Citations: 1     Fields:    
  7. Algarrahi K, Franck D, Cristofaro V, Yang X, Savarino A, Affas S, Schäfer FM, Ghezzi C, Jennings R, Nedder A, Kaplan DL, Sullivan MP, Estrada CR, Mauney JR. Bi-layer silk fibroin grafts support functional tissue regeneration in a porcine model of onlay esophagoplasty. J Tissue Eng Regen Med. 2018 02; 12(2):e894-e904. PMID: 28084044.
    Citations:    Fields:    
  8. Sack BS, Mauney JR, Estrada CR. Silk Fibroin Scaffolds for Urologic Tissue Engineering. Curr Urol Rep. 2016 Feb; 17(2):16. PMID: 26801192.
    Citations: 2     Fields:    Translation:HumansAnimals
  9. Chung YG, Seth A, Doyle C, Franck D, Kim D, Cristofaro V, Benowitz LI, Tu DD, Estrada CR, Mauney JR, Sullivan MP, Adam RM. Inosine Improves Neurogenic Detrusor Overactivity following Spinal Cord Injury. PLoS One. 2015; 10(11):e0141492. PMID: 26529505.
    Citations: 2     Fields:    Translation:Animals
  10. Algarrahi K, Franck D, Ghezzi CE, Cristofaro V, Yang X, Sullivan MP, Chung YG, Affas S, Jennings R, Kaplan DL, Estrada CR, Mauney JR. Acellular bi-layer silk fibroin scaffolds support functional tissue regeneration in a rat model of onlay esophagoplasty. Biomaterials. 2015 Jun; 53:149-59. PMID: 25890715.
    Citations: 2     Fields:    Translation:Animals
  11. Franck D, Chung YG, Coburn J, Kaplan DL, Estrada CR, Mauney JR. In vitro evaluation of bi-layer silk fibroin scaffolds for gastrointestinal tissue engineering. J Tissue Eng. 2014; 5:2041731414556849. PMID: 25396043.
    Citations: 4     
  12. Mauney JR, Adam RM. Dynamic reciprocity in cell-scaffold interactions. Adv Drug Deliv Rev. 2015 Mar; 82-83:77-85. PMID: 25453262.
    Citations: 4     Fields:    Translation:Humans
  13. Chung YG, Algarrahi K, Franck D, Tu DD, Adam RM, Kaplan DL, Estrada CR, Mauney JR. The use of bi-layer silk fibroin scaffolds and small intestinal submucosa matrices to support bladder tissue regeneration in a rat model of spinal cord injury. Biomaterials. 2014 Aug; 35(26):7452-9. PMID: 24917031.
    Citations: 11     Fields:    Translation:Animals
  14. Chung YG, Tu D, Franck D, Gil ES, Algarrahi K, Adam RM, Kaplan DL, Estrada CR, Mauney JR. Acellular bi-layer silk fibroin scaffolds support tissue regeneration in a rabbit model of onlay urethroplasty. PLoS One. 2014; 9(3):e91592. PMID: 24632740.
    Citations: 9     Fields:    Translation:Animals
  15. Gandhi D, Molotkov A, Batourina E, Schneider K, Dan H, Reiley M, Laufer E, Metzger D, Liang F, Liao Y, Sun TT, Aronow B, Rosen R, Mauney J, Adam R, Rosselot C, Van Batavia J, McMahon A, McMahon J, Guo JJ, Mendelsohn C. Retinoid signaling in progenitors controls specification and regeneration of the urothelium. Dev Cell. 2013 Sep 16; 26(5):469-482. PMID: 23993789.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  16. Tu DD, Chung YG, Gil ES, Seth A, Franck D, Cristofaro V, Sullivan MP, Di Vizio D, Gomez P, Adam RM, Kaplan DL, Estrada CR, Mauney JR. Bladder tissue regeneration using acellular bi-layer silk scaffolds in a large animal model of augmentation cystoplasty. Biomaterials. 2013 Nov; 34(34):8681-9. PMID: 23953839.
    Citations: 16     Fields:    Translation:Animals
  17. Seth A, Chung YG, Gil ES, Tu D, Franck D, Di Vizio D, Adam RM, Kaplan DL, Estrada CR, Mauney JR. The performance of silk scaffolds in a rat model of augmentation cystoplasty. Biomaterials. 2013 Jul; 34(20):4758-65. PMID: 23545287.
    Citations: 12     Fields:    Translation:Animals
  18. Franck D, Gil ES, Adam RM, Kaplan DL, Chung YG, Estrada CR, Mauney JR. Evaluation of silk biomaterials in combination with extracellular matrix coatings for bladder tissue engineering with primary and pluripotent cells. PLoS One. 2013; 8(2):e56237. PMID: 23409160.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  19. Tu DD, Seth A, Gil ES, Kaplan DL, Mauney JR, Estrada CR. Evaluation of biomaterials for bladder augmentation using cystometric analyses in various rodent models. J Vis Exp. 2012 Aug 09; (66). PMID: 22907252.
    Citations: 7     Fields:    Translation:Animals
  20. DeGraff DJ, Cates JM, Mauney JR, Clark PE, Matusik RJ, Adam RM. When urothelial differentiation pathways go wrong: implications for bladder cancer development and progression. Urol Oncol. 2013 Aug; 31(6):802-11. PMID: 21924649.
    Citations: 14     Fields:    Translation:HumansCells
  21. Gomez P, Gil ES, Lovett ML, Rockwood DN, Di Vizio D, Kaplan DL, Adam RM, Estrada CR, Mauney JR. The effect of manipulation of silk scaffold fabrication parameters on matrix performance in a murine model of bladder augmentation. Biomaterials. 2011 Oct; 32(30):7562-70. PMID: 21764119.
    Citations: 18     Fields:    Translation:Animals
  22. Kim J, Ji M, DiDonato JA, Rackley RR, Kuang M, Sadhukhan PC, Mauney JR, Keay SK, Freeman MR, Liou LS, Adam RM. An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor. In Vitro Cell Dev Biol Anim. 2011 Jan; 47(1):2-9. PMID: 21136194.
    Citations: 22     Fields:    Translation:HumansCells
  23. Mauney JR, Cannon GM, Lovett ML, Gong EM, Di Vizio D, Gomez P, Kaplan DL, Adam RM, Estrada CR. Evaluation of gel spun silk-based biomaterials in a murine model of bladder augmentation. Biomaterials. 2011 Jan; 32(3):808-18. PMID: 20951426.
    Citations: 28     Fields:    Translation:AnimalsCells
  24. Mauney J, Olsen BR, Volloch V. Matrix remodeling as stem cell recruitment event: a novel in vitro model for homing of human bone marrow stromal cells to the site of injury shows crucial role of extracellular collagen matrix. Matrix Biol. 2010 Oct; 29(8):657-63. PMID: 20828613.
    Citations: 14     Fields:    Translation:HumansCells
  25. Mauney JR, Ramachandran A, Yu RN, Daley GQ, Adam RM, Estrada CR. All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms. PLoS One. 2010 Jul 13; 5(7):e11513. PMID: 20644631.
    Citations: 23     Fields:    Translation:AnimalsCells
  26. Mauney J, Volloch V. Adult human bone marrow stromal cells regulate expression of their MMPs and TIMPs in differentiation type-specific manner. Matrix Biol. 2010 Jan; 29(1):3-8. PMID: 19765656.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  27. Mauney J, Volloch V. Human bone marrow-derived stromal cells show highly efficient stress-resistant adipogenesis on denatured collagen IV matrix but not on its native counterpart: implications for obesity. Matrix Biol. 2010 Jan; 29(1):9-14. PMID: 19761844.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  28. Mauney J, Volloch V. Progression of human bone marrow stromal cells into both osteogenic and adipogenic lineages is differentially regulated by structural conformation of collagen I matrix via distinct signaling pathways. Matrix Biol. 2009 Jun; 28(5):239-50. PMID: 19375503.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  29. Mauney J, Volloch V. Collagen I matrix contributes to determination of adult human stem cell lineage via differential, structural conformation-specific elicitation of cellular stress response. Matrix Biol. 2009 Jun; 28(5):251-62. PMID: 19375506.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  30. Egles C, Shamis Y, Mauney JR, Volloch V, Kaplan DL, Garlick JA. Denatured collagen modulates the phenotype of normal and wounded human skin equivalents. J Invest Dermatol. 2008 Jul; 128(7):1830-7. PMID: 18200055.
    Citations: 10     Fields:    Translation:HumansCells
  31. Moreau JE, Anderson K, Mauney JR, Nguyen T, Kaplan DL, Rosenblatt M. Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res. 2007 Nov 01; 67(21):10304-8. PMID: 17974972.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  32. Mauney JR, Nguyen T, Gillen K, Kirker-Head C, Gimble JM, Kaplan DL. Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials. 2007 Dec; 28(35):5280-90. PMID: 17765303.
    Citations: 85     Fields:    Translation:HumansAnimalsCells
  33. Moreau J, Anderson KM, Mauney JR, Kaplan D, Rosenblatt M. Studies of osteotropism on both sides of the breast cancer-bone interaction. Ann N Y Acad Sci. 2007 Nov; 1117:328-44. PMID: 17584985.
    Citations: 1     Fields:    Translation:HumansAnimals
  34. Mauney JR, Kirker-Head C, Abrahamson L, Gronowicz G, Volloch V, Kaplan DL. Matrix-mediated retention of in vitro osteogenic differentiation potential and in vivo bone-forming capacity by human adult bone marrow-derived mesenchymal stem cells during ex vivo expansion. J Biomed Mater Res A. 2006 Dec 01; 79(3):464-75. PMID: 16752403.
    Citations: 21     Fields:    Translation:HumansCells
  35. Mauney JR, Volloch V, Kaplan DL. Matrix-mediated retention of adipogenic differentiation potential by human adult bone marrow-derived mesenchymal stem cells during ex vivo expansion. Biomaterials. 2005 Nov; 26(31):6167-75. PMID: 15913765.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  36. Mauney JR, Jaquiéry C, Volloch V, Heberer M, Martin I, Kaplan DL. In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering. Biomaterials. 2005 Jun; 26(16):3173-85. PMID: 15603812.
    Citations: 34     Fields:    Translation:AnimalsCells
  37. Mauney JR, Volloch V, Kaplan DL. Role of adult mesenchymal stem cells in bone tissue engineering applications: current status and future prospects. Tissue Eng. 2005 May-Jun; 11(5-6):787-802. PMID: 15998219.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  38. Mauney JR, Kaplan DL, Volloch V. Matrix-mediated retention of osteogenic differentiation potential by human adult bone marrow stromal cells during ex vivo expansion. Biomaterials. 2004 Jul; 25(16):3233-43. PMID: 14980418.
    Citations: 26     Fields:    Translation:HumansCells
  39. Mauney JR, Sjostorm S, Blumberg J, Horan R, O'Leary JP, Vunjak-Novakovic G, Volloch V, Kaplan DL. Mechanical stimulation promotes osteogenic differentiation of human bone marrow stromal cells on 3-D partially demineralized bone scaffolds in vitro. Calcif Tissue Int. 2004 May; 74(5):458-68. PMID: 14961210.
    Citations: 42     Fields:    Translation:HumansCells
  40. Mauney JR, Blumberg J, Pirun M, Volloch V, Vunjak-Novakovic G, Kaplan DL. Osteogenic differentiation of human bone marrow stromal cells on partially demineralized bone scaffolds in vitro. Tissue Eng. 2004 Jan-Feb; 10(1-2):81-92. PMID: 15009933.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.