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Melissa Yeung, M.D., M.D.

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Biography
2008 - 2010
National Kidney Foundation Fellowship Grant
2010
Genzyme Basic Science Award
2010
American Society of Transplantation Young Investigator Award
2011 - 2016
American Heart Association Fellow-to-Faculty Transition Award
2013
American Association of Immunologists Abstract Award

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08AI128068 (YEUNG, MELISSA Y.) Jan 11, 2017 - Dec 31, 2021
    NIH
    TIM-1 and AhR: Key regulators of B-cell mediated Transplant Tolerance
  2. Paul Teschan Research Foundation (YEUNG, MELISSA Y.)
    Dialysis Clinic Inc.
    Defining Unacceptable Antigens in Organ Allocation: Balancing utility and equity of a rare resource

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yeung MY. Pre-formed DSA and kidney allograft outcomes. J Bras Nefrol. 2020 Jun 01; 42(2):136-137. PMID: 32495816.
    Citations:    Fields:    
  2. Choi JY, Eskandari SK, Cai S, Sulkaj I, Assaker JP, Allos H, AlHaddad J, Muhsin SA, Alhussain E, Mansouri A, Yeung MY, Seelen MAJ, Kim HJ, Cantor H, Azzi JR. Regulatory CD8 T cells that recognize Qa-1 expressed by CD4 T-helper cells inhibit rejection of heart allografts. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6042-6046. PMID: 32111690.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  3. Gordon WJ, Ainsworth L, Aronson S, Baronas J, Kaufman RM, Guleria I, Milford EL, Oates M, Paz RD, Yeung MY, Lane WJ. Development of a Calculated Panel Reactive Antibody Web Service with Local Frequencies for Platelet Transfusion Refractoriness Risk Stratification. J Pathol Inform. 2019; 10:26. PMID: 31463162.
    Citations:    
  4. Uffing A, Hidalgo LG, McMullan C, Perry J, Milford EL, Murakami N, Yeung MY, Guleria I, Wood IG, Akalin E, Azzi J, Chandraker AK, Riella LV. Preformed Donor-specific Antibodies Against HLA Class II and Graft Outcomes in Deceased-donor Kidney Transplantation. Transplant Direct. 2019 May; 5(5):e446. PMID: 31165081.
    Citations: 1     
  5. Kelly YP, Weins A, Yeung MY. Accelerated Oxalosis Contributing to Delayed Graft Function after Renal Transplantation. Case Rep Transplant. 2019; 2019:8942062. PMID: 31019830.
    Citations: 1     
  6. Yeung MY, Grimmig T, Sayegh MH. Costimulation Blockade in Transplantation. Adv Exp Med Biol. 2019; 1189:267-312. PMID: 31758538.
    Citations: 1     Fields:    Translation:HumansCells
  7. Yeung MY, Gabardi S, Sayegh MH. Use of polyclonal/monoclonal antibody therapies in transplantation. Expert Opin Biol Ther. 2017 03; 17(3):339-352. PMID: 28092486.
    Citations: 4     Fields:    Translation:HumansAnimals
  8. Ueno T, Kim P, McGrath MM, Yeung MY, Shimizu T, Jung K, Sayegh MH, Chandraker AK, Abdi R, Yun SH. Live Images of Donor Dendritic Cells Trafficking via CX3CR1 Pathway. Front Immunol. 2016; 7:412. PMID: 27790214.
    Citations: 2     Fields:    
  9. Ueno T, Jung K, Yeung MY, McGrath MM, Shimizu T, Kim P, Sayegh MH, Chandraker A, Yun SH. Imaging cell biology in transplantation. Transpl Int. 2016 Dec; 29(12):1349-1351. PMID: 27570933.
    Citations: 1     Fields:    Translation:Animals
  10. Laws LH, Parker CE, Cherala G, Koguchi Y, Waisman A, Slifka MK, Oberbarnscheidt MH, Obhrai JS, Yeung MY, Riella LV. Inflammation Causes Resistance to Anti-CD20-Mediated B Cell Depletion. Am J Transplant. 2016 11; 16(11):3139-3149. PMID: 27265023.
    Citations: 5     Fields:    Translation:AnimalsCells
  11. Ito T, Yamada A, Batal I, Yeung MY, McGrath MM, Sayegh MH, Chandraker A, Ueno T. The Limits of Linked Suppression for Regulatory T Cells. Front Immunol. 2016; 7:82. PMID: 27014262.
    Citations: 2     Fields:    
  12. Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV. KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation. EMBO J. 2015 Oct 01; 34(19):2441-64. PMID: 26282792.
    Citations: 20     Fields:    Translation:HumansCells
  13. Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV. KIM-1-mediated phagocytosis reduces acute injury to the kidney. J Clin Invest. 2015 Apr; 125(4):1620-36. PMID: 25751064.
    Citations: 78     Fields:    Translation:AnimalsCells
  14. Yeung MY, Ding Q, Brooks CR, Xiao S, Workman CJ, Vignali DA, Ueno T, Padera RF, Kuchroo VK, Najafian N, Rothstein DM. TIM-1 signaling is required for maintenance and induction of regulatory B cells. Am J Transplant. 2015 Apr; 15(4):942-53. PMID: 25645598.
    Citations: 33     Fields:    Translation:AnimalsCells
  15. Allegretti AS, Yeung MY, Riella LV. Counseling potential donors to the risk of ESRD after kidney donation: glass half-full or half-empty? Am J Transplant. 2014 Oct; 14(10):2434-5. PMID: 25167951.
    Citations:    Fields:    Translation:Humans
  16. Yeung MY, Najafian N, Sayegh MH. Targeting CD28 to prevent transplant rejection. Expert Opin Ther Targets. 2014 Feb; 18(2):225-42. PMID: 24329604.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  17. Yeung MY, McGrath MM, Nakayama M, Shimizu T, Boenisch O, Magee CN, Abdoli R, Akiba H, Ueno T, Turka LA, Najafian N. Interruption of dendritic cell-mediated TIM-4 signaling induces regulatory T cells and promotes skin allograft survival. J Immunol. 2013 Oct 15; 191(8):4447-55. PMID: 24038092.
    Citations: 15     Fields:    Translation:AnimalsCells
  18. D'Addio F, Boenisch O, Magee CN, Yeung MY, Yuan X, Mfarrej B, Vergani A, Ansari MJ, Fiorina P, Najafian N. Prolonged, low-dose anti-thymocyte globulin, combined with CTLA4-Ig, promotes engraftment in a stringent transplant model. PLoS One. 2013; 8(1):e53797. PMID: 23326509.
    Citations: 8     Fields:    Translation:HumansAnimals
  19. Ueno T, Yeung MY, McGrath M, Yang S, Zaman N, Snawder B, Padera RF, Magee CN, Gorbatov R, Hashiguchi M, Azuma M, Freeman GJ, Sayegh MH, Najafian N. Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses. Eur J Immunol. 2012 Sep; 42(9):2343-53. PMID: 22733595.
    Citations: 11     Fields:    Translation:AnimalsCells
  20. De Serres SA, Mfarrej BG, Grafals M, Riella LV, Magee CN, Yeung MY, Dyer C, Ahmad U, Chandraker A, Najafian N. Derivation and validation of a cytokine-based assay to screen for acute rejection in renal transplant recipients. Clin J Am Soc Nephrol. 2012 Jun; 7(6):1018-25. PMID: 22498498.
    Citations: 9     Fields:    Translation:HumansCells
  21. Zhao X, Boenisch O, Yeung M, Mfarrej B, Yang S, Turka LA, Sayegh MH, Iacomini J, Yuan X. Critical role of proinflammatory cytokine IL-6 in allograft rejection and tolerance. Am J Transplant. 2012 Jan; 12(1):90-101. PMID: 21992708.
    Citations: 27     Fields:    Translation:AnimalsCells
  22. D'Addio F, Riella LV, Mfarrej BG, Chabtini L, Adams LT, Yeung M, Yagita H, Azuma M, Sayegh MH, Guleria I. The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance. J Immunol. 2011 Nov 01; 187(9):4530-41. PMID: 21949023.
    Citations: 48     Fields:    Translation:AnimalsCells
  23. Ueno T, Yamada A, Ito T, Yeung MY, Gorbatov R, Shimizu T, Abdi R, Sayegh MH, Auchincloss H, Najafian N. Role of nuclear factor of activated T cell (NFAT) transcription factors in skin and vascularized cardiac allograft rejection. Transplantation. 2011 Sep 15; 92(5):e26-7. PMID: 21866037.
    Citations: 3     Fields:    Translation:AnimalsCells
  24. Yeung MY, McGrath M, Najafian N. The emerging role of the TIM molecules in transplantation. Am J Transplant. 2011 Oct; 11(10):2012-9. PMID: 21906254.
    Citations: 18     Fields:    Translation:HumansAnimals
  25. Ding Q, Yeung M, Camirand G, Zeng Q, Akiba H, Yagita H, Chalasani G, Sayegh MH, Najafian N, Rothstein DM. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest. 2011 Sep; 121(9):3645-56. PMID: 21821911.
    Citations: 175     Fields:    Translation:HumansAnimalsCells
  26. De Serres SA, Yeung MY, Mfarrej BG, Najafian N. Effect of biologic agents on regulatory T cells. Transplant Rev (Orlando). 2011 Jul; 25(3):110-6. PMID: 21514136.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  27. Riella LV, Watanabe T, Sage PT, Yang J, Yeung M, Azzi J, Vanguri V, Chandraker A, Sharpe AH, Sayegh MH, Najafian N. Essential role of PDL1 expression on nonhematopoietic donor cells in acquired tolerance to vascularized cardiac allografts. Am J Transplant. 2011 Apr; 11(4):832-40. PMID: 21401869.
    Citations: 14     Fields:    Translation:AnimalsCells
  28. Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N. TIM-3: a novel regulatory molecule of alloimmune activation. J Immunol. 2010 Nov 15; 185(10):5806-19. PMID: 20956339.
    Citations: 31     Fields:    Translation:AnimalsCells
  29. Yamaura K, Watanabe T, Boenisch O, Yeung M, Yang S, Magee CN, Padera R, Datta S, Schatton T, Kamimura Y, Azuma M, Najafian N. In vivo function of immune inhibitory molecule B7-H4 in alloimmune responses. Am J Transplant. 2010 Oct; 10(10):2355-62. PMID: 21143433.
    Citations: 8     Fields:    Translation:AnimalsCells
  30. Schröppel B, Krüger B, Walsh L, Yeung M, Harris S, Garrison K, Himmelfarb J, Lerner SM, Bromberg JS, Zhang PL, Bonventre JV, Wang Z, Farris AB, Colvin RB, Murphy BT, Vella JP. Tubular expression of KIM-1 does not predict delayed function after transplantation. J Am Soc Nephrol. 2010 Mar; 21(3):536-42. PMID: 20019169.
    Citations: 26     Fields:    Translation:Humans
  31. Ueno T, Ikeda T, Ikeda K, Taniuchi H, Suda S, Yeung MY, Matsuno N. HMGB-1 as a useful prognostic biomarker in sepsis-induced organ failure in patients undergoing PMX-DHP. J Surg Res. 2011 Nov; 171(1):183-90. PMID: 20338589.
    Citations: 11     Fields:    Translation:Humans
  32. Yeung MY, Sayegh MH. Regulatory T cells in transplantation: what we know and what we do not know. Transplant Proc. 2009 Jul-Aug; 41(6 Suppl):S21-6. PMID: 19651291.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.