Harvard Catalyst Profiles

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Wade G. Regehr, Ph.D.

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Mentoring
Calcium-Dependent Protein Kinase C Mediates Post-Tetanic Potentiation at the Calyx of Held
Summer, 06/01/10 - 09/30/10

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. UF1NS108177 (SABATINI, BERNARDO L) Sep 30, 2018 - Sep 29, 2021
    NIH/NINDS
    Controlling the spatial extent of light-based monitoring and manipulation of neural activity in vivo
    Role: Co-Principal Investigator
  2. R35NS097284 (REGEHR, WADE G) Dec 1, 2016 - Nov 30, 2024
    NIH/NINDS
    Mechanisms and Functions of Synapses and Circuits
    Role: Principal Investigator
  3. R01NS092707 (REGEHR, WADE G) Sep 22, 2015 - Jun 30, 2020
    NIH/NINDS
    Regulation of Synchrony and Input Layer Excitability by Purkinje Cell Collaterals
    Role: Principal Investigator
  4. R21NS093498 (REGEHR, WADE G) May 1, 2015 - Apr 30, 2017
    NIH/NINDS
    Using silk as a biocompatible viral delivery system in the brain
    Role: Principal Investigator
  5. P30NS072030 (SABATINI, BERNARDO L) Sep 30, 2011 - Aug 31, 2021
    NIH/NINDS
    HMS/BCH Center for Neuroscience Research
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jackman SL, Chen CH, Regehr WG. In Vivo Targeted Expression of Optogenetic Proteins Using Silk/AAV Films. J Vis Exp. 2019 Feb 26; (144). PMID: 30882792.
    Citations:    
  2. Weyrer C, Turecek J, Niday Z, Liu PW, Nanou E, Catterall WA, Bean BP, Regehr WG. The Role of CaV2.1 Channel Facilitation in Synaptic Facilitation. Cell Rep. 2019 Feb 26; 26(9):2289-2297.e3. PMID: 30811980.
    Citations:    
  3. Turecek J, Regehr WG. Neuronal Regulation of Fast Synaptotagmin Isoforms Controls the Relative Contributions of Synchronous and Asynchronous Release. Neuron. 2019 Mar 06; 101(5):938-949.e4. PMID: 30733150.
    Citations:    
  4. Tsai PT, Rudolph S, Guo C, Ellegood J, Gibson JM, Schaeffer SM, Mogavero J, Lerch JP, Regehr W, Sahin M. Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors. Cell Rep. 2018 Oct 09; 25(2):357-367.e4. PMID: 30304677.
    Citations:    Fields:    
  5. Han KS, Guo C, Chen CH, Witter L, Osorno T, Regehr WG. Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells. Neuron. 2018 Nov 07; 100(3):564-578.e3. PMID: 30293822.
    Citations:    Fields:    
  6. Turecek J, Regehr WG. Synaptotagmin 7 Mediates Both Facilitation and Asynchronous Release at Granule Cell Synapses. J Neurosci. 2018 Mar 28; 38(13):3240-3251. PMID: 29593071.
    Citations: 3     Fields:    
  7. Jackman SL, Chen CH, Chettih SN, Neufeld SQ, Drew IR, Agba CK, Flaquer I, Stefano AN, Kennedy TJ, Belinsky JE, Roberston K, Beron CC, Sabatini BL, Harvey CD, Regehr WG. Silk Fibroin Films Facilitate Single-Step Targeted Expression of Optogenetic Proteins. Cell Rep. 2018 03 20; 22(12):3351-3361. PMID: 29562189.
    Citations:    Fields:    
  8. Fioravante D, Chu Y, de Jong AP, Leitges M, Kaeser PS, Regehr WG. Retraction: Protein kinase C is a calcium sensor for presynaptic short-term plasticity. Elife. 2018 03 07; 7. PMID: 29512487.
    Citations:    Fields:    
  9. Turecek J, Jackman SL, Regehr WG. Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses. Nature. 2017 11 23; 551(7681):503-506. PMID: 29088700.
    Citations: 4     Fields:    Translation:AnimalsCells
  10. Jackman SL, Regehr WG. The Mechanisms and Functions of Synaptic Facilitation. Neuron. 2017 May 03; 94(3):447-464. PMID: 28472650.
    Citations: 19     Fields:    Translation:AnimalsCells
  11. Kaeser PS, Regehr WG. The readily releasable pool of synaptic vesicles. Curr Opin Neurobiol. 2017 04; 43:63-70. PMID: 28103533.
    Citations: 7     Fields:    Translation:HumansCells
  12. Turecek J, Jackman SL, Regehr WG. Synaptic Specializations Support Frequency-Independent Purkinje Cell Output from the Cerebellar Cortex. Cell Rep. 2016 12 20; 17(12):3256-3268. PMID: 28009294.
    Citations: 7     Fields:    Translation:AnimalsCells
  13. Guo C, Witter L, Rudolph S, Elliott HL, Ennis KA, Regehr WG. Purkinje Cells Directly Inhibit Granule Cells in Specialized Regions of the Cerebellar Cortex. Neuron. 2016 Sep 21; 91(6):1330-1341. PMID: 27593180.
    Citations: 6     Fields:    Translation:AnimalsCells
  14. Witter L, Rudolph S, Pressler RT, Lahlaf SI, Regehr WG. Purkinje Cell Collaterals Enable Output Signals from the Cerebellar Cortex to Feed Back to Purkinje Cells and Interneurons. Neuron. 2016 07 20; 91(2):312-9. PMID: 27346533.
    Citations: 10     Fields:    Translation:AnimalsCells
  15. Wang CC, Weyrer C, Paturu M, Fioravante D, Regehr WG. Calcium-Dependent Protein Kinase C Is Not Required for Post-Tetanic Potentiation at the Hippocampal CA3 to CA1 Synapse. J Neurosci. 2016 06 15; 36(24):6393-402. PMID: 27307229.
    Citations: 2     Fields:    Translation:AnimalsCells
  16. Thanawala MS, Regehr WG. Determining synaptic parameters using high-frequency activation. J Neurosci Methods. 2016 May 01; 264:136-152. PMID: 26972952.
    Citations: 6     Fields:    Translation:AnimalsCells
  17. Jackman SL, Turecek J, Belinsky JE, Regehr WG. The calcium sensor synaptotagmin 7 is required for synaptic facilitation. Nature. 2016 Jan 07; 529(7584):88-91. PMID: 26738595.
    Citations: 37     Fields:    Translation:AnimalsCells
  18. Rudolph S, Hull C, Regehr WG. Active Dendrites and Differential Distribution of Calcium Channels Enable Functional Compartmentalization of Golgi Cells. J Neurosci. 2015 Nov 25; 35(47):15492-504. PMID: 26609148.
    Citations: 4     Fields:    Translation:AnimalsCells
  19. Tang JC, Rudolph S, Dhande OS, Abraira VE, Choi S, Lapan SW, Drew IR, Drokhlyansky E, Huberman AD, Regehr WG, Cepko CL. Cell type-specific manipulation with GFP-dependent Cre recombinase. Nat Neurosci. 2015 Sep; 18(9):1334-41. PMID: 26258682.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  20. Fioravante D, Chu Y, de Jong AP, Leitges M, Kaeser PS, Regehr WG. Protein kinase C is a calcium sensor for presynaptic short-term plasticity. Elife. 2014 Aug 05; 3:e03011. PMID: 25097249.
    Citations: 10     Fields:    Translation:AnimalsCells
  21. Yamada T, Yang Y, Hemberg M, Yoshida T, Cho HY, Murphy JP, Fioravante D, Regehr WG, Gygi SP, Georgopoulos K, Bonni A. Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain. Neuron. 2014 Jul 02; 83(1):122-34. PMID: 24991957.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  22. Brenowitz SD, Regehr WG. Presynaptic calcium measurements using bulk loading of acetoxymethyl indicators. Cold Spring Harb Protoc. 2014 Jul 01; 2014(7):750-7. PMID: 24987144.
    Citations: 2     Fields:    Translation:AnimalsCells
  23. Antal M, Beneduce BM, Regehr WG. The substantia nigra conveys target-dependent excitatory and inhibitory outputs from the basal ganglia to the thalamus. J Neurosci. 2014 Jun 04; 34(23):8032-42. PMID: 24899724.
    Citations: 6     Fields:    Translation:AnimalsCells
  24. Jackman SL, Beneduce BM, Drew IR, Regehr WG. Achieving high-frequency optical control of synaptic transmission. J Neurosci. 2014 May 28; 34(22):7704-14. PMID: 24872574.
    Citations: 33     Fields:    Translation:AnimalsCells
  25. Chu Y, Fioravante D, Leitges M, Regehr WG. Calcium-dependent PKC isoforms have specialized roles in short-term synaptic plasticity. Neuron. 2014 May 21; 82(4):859-71. PMID: 24794094.
    Citations: 11     Fields:    Translation:AnimalsCells
  26. Kaeser PS, Regehr WG. Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release. Annu Rev Physiol. 2014; 76:333-63. PMID: 24274737.
    Citations: 74     Fields:    Translation:HumansAnimalsCells
  27. Liu A, Regehr WG. Normalization of input patterns in an associative network. J Neurophysiol. 2014 Feb; 111(3):544-51. PMID: 24225543.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  28. Hull CA, Chu Y, Thanawala M, Regehr WG. Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. J Neurosci. 2013 Apr 03; 33(14):5895-902. PMID: 23554471.
    Citations: 13     Fields:    Translation:AnimalsCells
  29. Thanawala MS, Regehr WG. Presynaptic calcium influx controls neurotransmitter release in part by regulating the effective size of the readily releasable pool. J Neurosci. 2013 Mar 13; 33(11):4625-33. PMID: 23486937.
    Citations: 35     Fields:    Translation:AnimalsCells
  30. Pressler RT, Regehr WG. Metabotropic glutamate receptors drive global persistent inhibition in the visual thalamus. J Neurosci. 2013 Feb 06; 33(6):2494-506. PMID: 23392677.
    Citations: 8     Fields:    Translation:AnimalsCells
  31. Chu Y, Fioravante D, Thanawala M, Leitges M, Regehr WG. Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held. J Neurosci. 2012 Oct 03; 32(40):13796-804. PMID: 23035091.
    Citations: 10     Fields:    Translation:AnimalsCells
  32. Fioravante D, Myoga MH, Leitges M, Regehr WG. Adaptive regulation maintains posttetanic potentiation at cerebellar granule cell synapses in the absence of calcium-dependent PKC. J Neurosci. 2012 Sep 19; 32(38):13004-9. PMID: 22993418.
    Citations: 5     Fields:    Translation:AnimalsCells
  33. Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature. 2012 Aug 30; 488(7413):647-51. PMID: 22763451.
    Citations: 210     Fields:    Translation:AnimalsCells
  34. Regehr WG. Short-term presynaptic plasticity. Cold Spring Harb Perspect Biol. 2012 Jul 01; 4(7):a005702. PMID: 22751149.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  35. Brenowitz SD, Regehr WG. Presynaptic imaging of projection fibers by in vivo injection of dextran-conjugated calcium indicators. Cold Spring Harb Protoc. 2012 Apr 01; 2012(4):465-71. PMID: 22474660.
    Citations:    Fields:    Translation:AnimalsCells
  36. Hull C, Regehr WG. Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity. Neuron. 2012 Jan 12; 73(1):149-58. PMID: 22243753.
    Citations: 40     Fields:    Translation:AnimalsCells
  37. Fioravante D, Chu Y, Myoga MH, Leitges M, Regehr WG. Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held. Neuron. 2011 Jun 09; 70(5):1005-19. PMID: 21658591.
    Citations: 25     Fields:    Translation:AnimalsCells
  38. Myoga MH, Regehr WG. Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses. J Neurosci. 2011 Apr 06; 31(14):5235-43. PMID: 21471358.
    Citations: 14     Fields:    Translation:AnimalsCells
  39. Fioravante D, Regehr WG. Short-term forms of presynaptic plasticity. Curr Opin Neurobiol. 2011 Apr; 21(2):269-74. PMID: 21353526.
    Citations: 99     Fields:    Translation:HumansAnimalsCells
  40. Carey MR, Myoga MH, McDaniels KR, Marsicano G, Lutz B, Mackie K, Regehr WG. Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. J Neurophysiol. 2011 Feb; 105(2):958-63. PMID: 21084685.
    Citations: 16     Fields:    Translation:AnimalsCells
  41. Carey MR, Regehr WG. Phosphatase activity controls the ups and downs of cerebellar learning. Neuron. 2010 Aug 26; 67(4):525-6. PMID: 20797529.
    Citations: 1     Fields:    
  42. Antal M, Acuna-Goycolea C, Pressler RT, Blitz DM, Regehr WG. Cholinergic activation of M2 receptors leads to context-dependent modulation of feedforward inhibition in the visual thalamus. PLoS Biol. 2010 Apr 06; 8(4):e1000348. PMID: 20386723.
    Citations: 7     Fields:    Translation:AnimalsCells
  43. Best AR, Regehr WG. Identification of the synthetic pathway producing the endocannabinoid that mediates the bulk of retrograde signaling in the brain. Neuron. 2010 Feb 11; 65(3):291-2. PMID: 20159441.
    Citations: 4     Fields:    Translation:AnimalsCells
  44. Crowley JJ, Fioravante D, Regehr WG. Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integration. Neuron. 2009 Sep 24; 63(6):843-53. PMID: 19778512.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  45. Kim JC, Cook MN, Carey MR, Shen C, Regehr WG, Dymecki SM. Linking genetically defined neurons to behavior through a broadly applicable silencing allele. Neuron. 2009 Aug 13; 63(3):305-15. PMID: 19679071.
    Citations: 46     Fields:    Translation:AnimalsCells
  46. Regehr WG, Carey MR, Best AR. Activity-dependent regulation of synapses by retrograde messengers. Neuron. 2009 Jul 30; 63(2):154-70. PMID: 19640475.
    Citations: 85     Fields:    Translation:HumansAnimalsCells
  47. Myoga MH, Beierlein M, Regehr WG. Somatic spikes regulate dendritic signaling in small neurons in the absence of backpropagating action potentials. J Neurosci. 2009 Jun 17; 29(24):7803-14. PMID: 19535592.
    Citations: 11     Fields:    Translation:AnimalsCells
  48. Best AR, Regehr WG. Inhibitory regulation of electrically coupled neurons in the inferior olive is mediated by asynchronous release of GABA. Neuron. 2009 May 28; 62(4):555-65. PMID: 19477156.
    Citations: 47     Fields:    Translation:AnimalsCells
  49. Carey MR, Regehr WG. Noradrenergic control of associative synaptic plasticity by selective modulation of instructive signals. Neuron. 2009 Apr 16; 62(1):112-22. PMID: 19376071.
    Citations: 20     Fields:    Translation:AnimalsCells
  50. Xu-Friedman MA, Regehr WG. Retrograde tuning of tuning. Neuron. 2008 Jul 10; 59(1):3-5. PMID: 18614023.
    Citations:    Fields:    Translation:AnimalsCells
  51. Best AR, Regehr WG. Serotonin evokes endocannabinoid release and retrogradely suppresses excitatory synapses. J Neurosci. 2008 Jun 18; 28(25):6508-15. PMID: 18562622.
    Citations: 31     Fields:    Translation:AnimalsCells
  52. Acuna-Goycolea C, Brenowitz SD, Regehr WG. Active dendritic conductances dynamically regulate GABA release from thalamic interneurons. Neuron. 2008 Feb 07; 57(3):420-31. PMID: 18255034.
    Citations: 33     Fields:    Translation:AnimalsCells
  53. Brenowitz SD, Regehr WG. Reliability and heterogeneity of calcium signaling at single presynaptic boutons of cerebellar granule cells. J Neurosci. 2007 Jul 25; 27(30):7888-98. PMID: 17652580.
    Citations: 44     Fields:    Translation:AnimalsCells
  54. Safo P, Regehr WG. Timing dependence of the induction of cerebellar LTD. Neuropharmacology. 2008 Jan; 54(1):213-8. PMID: 17669443.
    Citations: 29     Fields:    Translation:AnimalsCells
  55. Beierlein M, Fioravante D, Regehr WG. Differential expression of posttetanic potentiation and retrograde signaling mediate target-dependent short-term synaptic plasticity. Neuron. 2007 Jun 21; 54(6):949-59. PMID: 17582334.
    Citations: 34     Fields:    Translation:AnimalsCells
  56. Crowley JJ, Carter AG, Regehr WG. Fast vesicle replenishment and rapid recovery from desensitization at a single synaptic release site. J Neurosci. 2007 May 16; 27(20):5448-60. PMID: 17507567.
    Citations: 22     Fields:    Translation:AnimalsCells
  57. Beierlein M, Regehr WG. Local interneurons regulate synaptic strength by retrograde release of endocannabinoids. J Neurosci. 2006 Sep 27; 26(39):9935-43. PMID: 17005857.
    Citations: 32     Fields:    Translation:AnimalsCells
  58. Beierlein M, Regehr WG. Brief bursts of parallel fiber activity trigger calcium signals in bergmann glia. J Neurosci. 2006 Jun 28; 26(26):6958-67. PMID: 16807325.
    Citations: 27     Fields:    Translation:AnimalsCells
  59. Brenowitz SD, Best AR, Regehr WG. Sustained elevation of dendritic calcium evokes widespread endocannabinoid release and suppression of synapses onto cerebellar Purkinje cells. J Neurosci. 2006 Jun 21; 26(25):6841-50. PMID: 16793891.
    Citations: 20     Fields:    Translation:AnimalsCells
  60. Safo PK, Cravatt BF, Regehr WG. Retrograde endocannabinoid signaling in the cerebellar cortex. Cerebellum. 2006; 5(2):134-45. PMID: 16818388.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  61. Foster KA, Crowley JJ, Regehr WG. The influence of multivesicular release and postsynaptic receptor saturation on transmission at granule cell to Purkinje cell synapses. J Neurosci. 2005 Dec 14; 25(50):11655-65. PMID: 16354924.
    Citations: 32     Fields:    Translation:AnimalsCells
  62. Safo PK, Regehr WG. Endocannabinoids control the induction of cerebellar LTD. Neuron. 2005 Nov 23; 48(4):647-59. PMID: 16301180.
    Citations: 86     Fields:    Translation:AnimalsCells
  63. Xu-Friedman MA, Regehr WG. Dynamic-clamp analysis of the effects of convergence on spike timing. II. Few synaptic inputs. J Neurophysiol. 2005 Oct; 94(4):2526-34. PMID: 16160093.
    Citations: 18     Fields:    Translation:AnimalsCells
  64. Xu-Friedman MA, Regehr WG. Dynamic-clamp analysis of the effects of convergence on spike timing. I. Many synaptic inputs. J Neurophysiol. 2005 Oct; 94(4):2512-25. PMID: 16160092.
    Citations: 19     Fields:    Translation:AnimalsCells
  65. Beierlein M, Regehr WG. Conventional synapses for unconventional cells. Neuron. 2005 Jun 02; 46(5):694-6. PMID: 15924854.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  66. Blitz DM, Regehr WG. Timing and specificity of feed-forward inhibition within the LGN. Neuron. 2005 Mar 24; 45(6):917-28. PMID: 15797552.
    Citations: 62     Fields:    Translation:AnimalsCells
  67. Brenowitz SD, Regehr WG. Associative short-term synaptic plasticity mediated by endocannabinoids. Neuron. 2005 Feb 03; 45(3):419-31. PMID: 15694328.
    Citations: 62     Fields:    Translation:AnimalsCells
  68. Abbott LF, Regehr WG. Synaptic computation. Nature. 2004 Oct 14; 431(7010):796-803. PMID: 15483601.
    Citations: 267     Fields:    Translation:AnimalsCells
  69. Blitz DM, Foster KA, Regehr WG. Short-term synaptic plasticity: a comparison of two synapses. Nat Rev Neurosci. 2004 Aug; 5(8):630-40. PMID: 15263893.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  70. Foster KA, Regehr WG. Variance-mean analysis in the presence of a rapid antagonist indicates vesicle depletion underlies depression at the climbing fiber synapse. Neuron. 2004 Jul 08; 43(1):119-31. PMID: 15233922.
    Citations: 35     Fields:    Translation:AnimalsCells
  71. Beierlein M, Gee KR, Martin VV, Regehr WG. Presynaptic calcium measurements at physiological temperatures using a new class of dextran-conjugated indicators. J Neurophysiol. 2004 Jul; 92(1):591-9. PMID: 15212445.
    Citations: 15     Fields:    Translation:AnimalsCells
  72. Brown SP, Safo PK, Regehr WG. Endocannabinoids inhibit transmission at granule cell to Purkinje cell synapses by modulating three types of presynaptic calcium channels. J Neurosci. 2004 Jun 16; 24(24):5623-31. PMID: 15201335.
    Citations: 49     Fields:    Translation:AnimalsCells
  73. Xu-Friedman MA, Regehr WG. Structural contributions to short-term synaptic plasticity. Physiol Rev. 2004 Jan; 84(1):69-85. PMID: 14715911.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  74. Blitz DM, Regehr WG. Retinogeniculate synaptic properties controlling spike number and timing in relay neurons. J Neurophysiol. 2003 Oct; 90(4):2438-50. PMID: 14534270.
    Citations: 21     Fields:    Translation:AnimalsCells
  75. Brown SP, Brenowitz SD, Regehr WG. Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids. Nat Neurosci. 2003 Oct; 6(10):1048-57. PMID: 14502290.
    Citations: 81     Fields:    Translation:AnimalsCells
  76. Brenowitz SD, Regehr WG. "Resistant" channels reluctantly reveal their roles. Neuron. 2003 Jul 31; 39(3):391-4. PMID: 12895414.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  77. Brenowitz SD, Regehr WG. Calcium dependence of retrograde inhibition by endocannabinoids at synapses onto Purkinje cells. J Neurosci. 2003 Jul 16; 23(15):6373-84. PMID: 12867523.
    Citations: 27     Fields:    Translation:AnimalsCells
  78. Chen C, Regehr WG. Presynaptic modulation of the retinogeniculate synapse. J Neurosci. 2003 Apr 15; 23(8):3130-5. PMID: 12716920.
    Citations: 33     Fields:    Translation:AnimalsCells
  79. Xu-Friedman MA, Regehr WG. Ultrastructural contributions to desensitization at cerebellar mossy fiber to granule cell synapses. J Neurosci. 2003 Mar 15; 23(6):2182-92. PMID: 12657677.
    Citations: 45     Fields:    Translation:AnimalsCells
  80. Foster KA, Kreitzer AC, Regehr WG. Interaction of postsynaptic receptor saturation with presynaptic mechanisms produces a reliable synapse. Neuron. 2002 Dec 19; 36(6):1115-26. PMID: 12495626.
    Citations: 31     Fields:    Translation:AnimalsCells
  81. Carter AG, Regehr WG. Quantal events shape cerebellar interneuron firing. Nat Neurosci. 2002 Dec; 5(12):1309-18. PMID: 12411959.
    Citations: 66     Fields:    Translation:AnimalsCells
  82. Kreitzer AC, Regehr WG. Retrograde signaling by endocannabinoids. Curr Opin Neurobiol. 2002 Jun; 12(3):324-30. PMID: 12049940.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  83. Kreitzer AC, Carter AG, Regehr WG. Inhibition of interneuron firing extends the spread of endocannabinoid signaling in the cerebellum. Neuron. 2002 May 30; 34(5):787-96. PMID: 12062024.
    Citations: 48     Fields:    Translation:AnimalsCells
  84. Chen C, Blitz DM, Regehr WG. Contributions of receptor desensitization and saturation to plasticity at the retinogeniculate synapse. Neuron. 2002 Feb 28; 33(5):779-88. PMID: 11879654.
    Citations: 48     Fields:    Translation:AnimalsCells
  85. Zucker RS, Regehr WG. Short-term synaptic plasticity. Annu Rev Physiol. 2002; 64:355-405. PMID: 11826273.
    Citations: 1073     Fields:    Translation:AnimalsCells
  86. Carter AG, Vogt KE, Foster KA, Regehr WG. Assessing the role of calcium-induced calcium release in short-term presynaptic plasticity at excitatory central synapses. J Neurosci. 2002 Jan 01; 22(1):21-8. PMID: 11756484.
    Citations: 41     Fields:    Translation:AnimalsCells
  87. Kreitzer AC, Regehr WG. Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids. J Neurosci. 2001 Oct 15; 21(20):RC174. PMID: 11588204.
    Citations: 78     Fields:    Translation:AnimalsCells
  88. Xu-Friedman MA, Harris KM, Regehr WG. Three-dimensional comparison of ultrastructural characteristics at depressing and facilitating synapses onto cerebellar Purkinje cells. J Neurosci. 2001 Sep 01; 21(17):6666-72. PMID: 11517256.
    Citations: 71     Fields:    Translation:AnimalsCells
  89. Kreitzer AC, Regehr WG. Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron. 2001 Mar; 29(3):717-27. PMID: 11301030.
    Citations: 228     Fields:    Translation:AnimalsCells
  90. Vogt KE, Regehr WG. Cholinergic modulation of excitatory synaptic transmission in the CA3 area of the hippocampus. J Neurosci. 2001 Jan 01; 21(1):75-83. PMID: 11150322.
    Citations: 41     Fields:    Translation:AnimalsCells
  91. Xu-Friedman MA, Regehr WG. Maximinis. Nat Neurosci. 2000 Dec; 3(12):1229-30. PMID: 11100136.
    Citations:    Fields:    Translation:HumansAnimalsCells
  92. Chen C, Regehr WG. Developmental remodeling of the retinogeniculate synapse. Neuron. 2000 Dec; 28(3):955-66. PMID: 11163279.
    Citations: 137     Fields:    Translation:AnimalsCells
  93. Kreitzer AC, Gee KR, Archer EA, Regehr WG. Monitoring presynaptic calcium dynamics in projection fibers by in vivo loading of a novel calcium indicator. Neuron. 2000 Jul; 27(1):25-32. PMID: 10939328.
    Citations: 22     Fields:    Translation:AnimalsCells
  94. Xu-Friedman MA, Regehr WG. Probing fundamental aspects of synaptic transmission with strontium. J Neurosci. 2000 Jun 15; 20(12):4414-22. PMID: 10844010.
    Citations: 52     Fields:    Translation:AnimalsCells
  95. Carter AG, Regehr WG. Prolonged synaptic currents and glutamate spillover at the parallel fiber to stellate cell synapse. J Neurosci. 2000 Jun 15; 20(12):4423-34. PMID: 10844011.
    Citations: 74     Fields:    Translation:AnimalsCells
  96. Kreitzer AC, Regehr WG. Modulation of transmission during trains at a cerebellar synapse. J Neurosci. 2000 Feb 15; 20(4):1348-57. PMID: 10662825.
    Citations: 25     Fields:    Translation:AnimalsCells
  97. Dittman JS, Kreitzer AC, Regehr WG. Interplay between facilitation, depression, and residual calcium at three presynaptic terminals. J Neurosci. 2000 Feb 15; 20(4):1374-85. PMID: 10662828.
    Citations: 144     Fields:    Translation:AnimalsCells
  98. Chen C, Regehr WG. Contributions of residual calcium to fast synaptic transmission. J Neurosci. 1999 Aug 01; 19(15):6257-66. PMID: 10414955.
    Citations: 24     Fields:    Translation:AnimalsCells
  99. Xu-Friedman MA, Regehr WG. Presynaptic strontium dynamics and synaptic transmission. Biophys J. 1999 Apr; 76(4):2029-42. PMID: 10096899.
    Citations: 36     Fields:    Translation:AnimalsCells
  100. Sabatini BL, Regehr WG. Timing of synaptic transmission. Annu Rev Physiol. 1999; 61:521-42. PMID: 10099700.
    Citations: 56     Fields:    Translation:AnimalsCells
  101. Atluri PP, Regehr WG. Delayed release of neurotransmitter from cerebellar granule cells. J Neurosci. 1998 Oct 15; 18(20):8214-27. PMID: 9763467.
    Citations: 77     Fields:    Translation:AnimalsCells
  102. Dittman JS, Regehr WG. Calcium dependence and recovery kinetics of presynaptic depression at the climbing fiber to Purkinje cell synapse. J Neurosci. 1998 Aug 15; 18(16):6147-62. PMID: 9698309.
    Citations: 122     Fields:    Translation:AnimalsCells
  103. Sabatini BL, Regehr WG. Optical measurement of presynaptic calcium currents. Biophys J. 1998 Mar; 74(3):1549-63. PMID: 9512051.
    Citations: 31     Fields:    Translation:AnimalsCells
  104. Dittman JS, Regehr WG. Mechanism and kinetics of heterosynaptic depression at a cerebellar synapse. J Neurosci. 1997 Dec 01; 17(23):9048-59. PMID: 9364051.
    Citations: 35     Fields:    Translation:AnimalsCells
  105. Chen C, Regehr WG. The mechanism of cAMP-mediated enhancement at a cerebellar synapse. J Neurosci. 1997 Nov 15; 17(22):8687-94. PMID: 9348337.
    Citations: 47     Fields:    Translation:AnimalsCells
  106. Regehr WG. Interplay between sodium and calcium dynamics in granule cell presynaptic terminals. Biophys J. 1997 Nov; 73(5):2476-88. PMID: 9370441.
    Citations: 20     Fields:    Translation:AnimalsCells
  107. Sabatini BL, Regehr WG. Control of neurotransmitter release by presynaptic waveform at the granule cell to Purkinje cell synapse. J Neurosci. 1997 May 15; 17(10):3425-35. PMID: 9133368.
    Citations: 78     Fields:    Translation:AnimalsCells
  108. Connors BW, Regehr WG. Neuronal firing: does function follow form? Curr Biol. 1996 Dec 01; 6(12):1560-2. PMID: 8994812.
    Citations: 7     Fields:    Translation:AnimalsCells
  109. Sabatini BL, Regehr WG. Timing of neurotransmission at fast synapses in the mammalian brain. Nature. 1996 Nov 14; 384(6605):170-2. PMID: 8906792.
    Citations: 96     Fields:    Translation:AnimalsCells
  110. Atluri PP, Regehr WG. Determinants of the time course of facilitation at the granule cell to Purkinje cell synapse. J Neurosci. 1996 Sep 15; 16(18):5661-71. PMID: 8795622.
    Citations: 112     Fields:    Translation:AnimalsCells
  111. Dittman JS, Regehr WG. Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse. J Neurosci. 1996 Mar 01; 16(5):1623-33. PMID: 8774431.
    Citations: 77     Fields:    Translation:AnimalsCells
  112. Tank DW, Regehr WG, Delaney KR. A quantitative analysis of presynaptic calcium dynamics that contribute to short-term enhancement. J Neurosci. 1995 Dec; 15(12):7940-52. PMID: 8613732.
    Citations: 50     Fields:    Translation:AnimalsCells
  113. Sabatini BL, Regehr WG. Detecting changes in calcium influx which contribute to synaptic modulation in mammalian brain slice. Neuropharmacology. 1995 Nov; 34(11):1453-67. PMID: 8606793.
    Citations: 11     Fields:    Translation:AnimalsCells
  114. Mintz IM, Sabatini BL, Regehr WG. Calcium control of transmitter release at a cerebellar synapse. Neuron. 1995 Sep; 15(3):675-88. PMID: 7546746.
    Citations: 152     Fields:    Translation:AnimalsCells
  115. Regehr WG, Atluri PP. Calcium transients in cerebellar granule cell presynaptic terminals. Biophys J. 1995 May; 68(5):2156-70. PMID: 7612860.
    Citations: 51     Fields:    Translation:AnimalsCells
  116. Regehr WG, Tank DW. Dendritic calcium dynamics. Curr Opin Neurobiol. 1994 Jun; 4(3):373-82. PMID: 7919932.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  117. Regehr WG, Armstrong CM. Dendritic function. Where does it all begin? Curr Biol. 1994 May 01; 4(5):436-9. PMID: 7922359.
    Citations: 3     Fields:    Translation:AnimalsCells
  118. Regehr WG, Mintz IM. Participation of multiple calcium channel types in transmission at single climbing fiber to Purkinje cell synapses. Neuron. 1994 Mar; 12(3):605-13. PMID: 8155322.
    Citations: 43     Fields:    Translation:AnimalsCells
  119. Regehr WG, Delaney KR, Tank DW. The role of presynaptic calcium in short-term enhancement at the hippocampal mossy fiber synapse. J Neurosci. 1994 Feb; 14(2):523-37. PMID: 8301352.
    Citations: 70     Fields:    Translation:AnimalsCells
  120. Regehr W, Kehoe JS, Ascher P, Armstrong C. Synaptically triggered action potentials in dendrites. Neuron. 1993 Jul; 11(1):145-51. PMID: 8338663.
    Citations: 17     Fields:    Translation:AnimalsCells
  121. Regehr WG, Tank DW. Calcium concentration dynamics produced by synaptic activation of CA1 hippocampal pyramidal cells. J Neurosci. 1992 Nov; 12(11):4202-23. PMID: 1359030.
    Citations: 42     Fields:    Translation:AnimalsCells
  122. Regehr WG, Konnerth A, Armstrong CM. Sodium action potentials in the dendrites of cerebellar Purkinje cells. Proc Natl Acad Sci U S A. 1992 Jun 15; 89(12):5492-6. PMID: 1608959.
    Citations: 6     Fields:    Translation:AnimalsCells
  123. Garyantes TK, Regehr WG. Electrical activity increases growth cone calcium but fails to inhibit neurite outgrowth from rat sympathetic neurons. J Neurosci. 1992 Jan; 12(1):96-103. PMID: 1729445.
    Citations: 5     Fields:    Translation:AnimalsCells
  124. Regehr WG, Tank DW. The maintenance of LTP at hippocampal mossy fiber synapses is independent of sustained presynaptic calcium. Neuron. 1991 Sep; 7(3):451-9. PMID: 1654950.
    Citations: 15     Fields:    Translation:AnimalsCells
  125. Regehr WG, Tank DW. Selective fura-2 loading of presynaptic terminals and nerve cell processes by local perfusion in mammalian brain slice. J Neurosci Methods. 1991 Apr; 37(2):111-9. PMID: 1881195.
    Citations: 33     Fields:    Translation:Animals
  126. Regehr WG, Tank DW. Postsynaptic NMDA receptor-mediated calcium accumulation in hippocampal CA1 pyramidal cell dendrites. Nature. 1990 Jun 28; 345(6278):807-10. PMID: 1972782.
    Citations: 25     Fields:    Translation:AnimalsCells
  127. Regehr WG, Pine J, Cohan CS, Mischke MD, Tank DW. Sealing cultured invertebrate neurons to embedded dish electrodes facilitates long-term stimulation and recording. J Neurosci Methods. 1989 Nov; 30(2):91-106. PMID: 2586157.
    Citations: 21     Fields:    Translation:AnimalsCells
  128. Regehr WG, Connor JA, Tank DW. Optical imaging of calcium accumulation in hippocampal pyramidal cells during synaptic activation. Nature. 1989 Oct 12; 341(6242):533-6. PMID: 2797180.
    Citations: 38     Fields:    Translation:AnimalsCells
  129. Regehr WG, Pine J, Rutledge DB. A long-term in vitro silicon-based microelectrode-neuron connection. IEEE Trans Biomed Eng. 1988 Dec; 35(12):1023-32. PMID: 3220496.
    Citations: 3     Fields:    Translation:Cells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.