Harvard Catalyst Profiles

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Joseph V. Geisberg, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Geisberg JV, Moqtaderi Z, Fong N, Erickson B, Bentley DL, Struhl K. Nucleotide-level linkage of transcriptional elongation and polyadenylation. Elife. 2022 11 24; 11. PMID: 36421680; PMCID: PMC9721619.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  2. Lui KH, Geisberg JV, Moqtaderi Z, Struhl K. 3' Untranslated Regions Are Modular Entities That Determine Polyadenylation Profiles. Mol Cell Biol. 2022 09 15; 42(9):e0024422. PMID: 35972270; PMCID: PMC9476944.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Moqtaderi Z, Geisberg JV, Struhl K. A compensatory link between cleavage/polyadenylation and mRNA turnover regulates steady-state mRNA levels in yeast. Proc Natl Acad Sci U S A. 2022 01 25; 119(4). PMID: 35058367; PMCID: PMC8794773.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Geisberg JV, Moqtaderi Z, Struhl K. The transcriptional elongation rate regulates alternative polyadenylation in yeast. Elife. 2020 08 26; 9. PMID: 32845240.
    Citations: 7     Fields:    Translation:AnimalsCells
  5. Geisberg JV, Moqtaderi Z. Protein Binding to mRNA 3' Isoforms. Curr Protoc Mol Biol. 2019 09; 128(1):e101. PMID: 31503412.
    Citations:    Fields:    Translation:AnimalsCells
  6. Moqtaderi Z, Geisberg JV. Probing In Vivo Structure of Individual mRNA 3' Isoforms Using Dimethyl Sulfate. Curr Protoc Mol Biol. 2019 09; 128(1):e99. PMID: 31503415.
    Citations:    Fields:    Translation:AnimalsCells
  7. Moqtaderi Z, Geisberg JV, Struhl K. Extensive Structural Differences of Closely Related 3' mRNA Isoforms: Links to Pab1 Binding and mRNA Stability. Mol Cell. 2018 12 06; 72(5):849-861.e6. PMID: 30318446; PMCID: PMC6289678.
    Citations: 14     Fields:    Translation:AnimalsCells
  8. Geisberg JV, Moqtaderi Z. Genome-Wide Study of mRNA Isoform Half-Lives. Methods Mol Biol. 2016; 1358:317-23. PMID: 26463393.
    Citations:    Fields:    Translation:AnimalsCells
  9. Jin Y, Geisberg JV, Moqtaderi Z, Ji Z, Hoque M, Tian B, Struhl K. Mapping 3' mRNA isoforms on a genomic scale. Curr Protoc Mol Biol. 2015 Apr 01; 110:4.23.1-4.23.17. PMID: 25827089.
    Citations: 7     Fields:    
  10. Moqtaderi Z, Geisberg JV, Struhl K. Secondary structures involving the poly(A) tail and other 3' sequences are major determinants of mRNA isoform stability in yeast. Microb Cell. 2014 Apr; 1(4):137-139. PMID: 25279376.
    Citations: 4     
  11. Geisberg JV, Moqtaderi Z, Fan X, Ozsolak F, Struhl K. Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast. Cell. 2014 Feb 13; 156(4):812-24. PMID: 24529382.
    Citations: 111     Fields:    Translation:AnimalsCells
  12. Moqtaderi Z, Geisberg JV. Construction of mutant alleles in Saccharomyces cerevisiae without cloning: overview and the delitto perfetto method. Curr Protoc Mol Biol. 2013 Oct 11; 104:13.10C.1-13.10C.17. PMID: 24510296.
    Citations: 3     Fields:    Translation:Animals
  13. Moqtaderi Z, Geisberg JV, Jin Y, Fan X, Struhl K. Species-specific factors mediate extensive heterogeneity of mRNA 3' ends in yeasts. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):11073-8. PMID: 23776204.
    Citations: 26     Fields:    Translation:AnimalsCells
  14. Geisberg JV, Basque T. Carryover test in frozen serum cored by an automated frozen sample aliquotter. Biopreserv Biobank. 2011 Dec; 9(4):373-7. PMID: 24836633.
    Citations:    Fields:    
  15. Fan X, Geisberg JV, Wong KH, Jin Y. Conditional depletion of nuclear proteins by the Anchor Away system. Curr Protoc Mol Biol. 2011 Jan; Chapter 13:Unit13.10B. PMID: 21225637.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  16. Geisberg JV, Struhl K. Analysis of protein co-occupancy by quantitative sequential chromatin immunoprecipitation. Curr Protoc Mol Biol. 2005 May; Chapter 21:Unit 21.8. PMID: 18265359.
    Citations: 10     Fields:    
  17. Aparicio O, Geisberg JV, Sekinger E, Yang A, Moqtaderi Z, Struhl K. Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo. Curr Protoc Mol Biol. 2005 Feb; Chapter 21:Unit 21.3. PMID: 18265358.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  18. Geisberg JV, Struhl K. Quantitative sequential chromatin immunoprecipitation, a method for analyzing co-occupancy of proteins at genomic regions in vivo. Nucleic Acids Res. 2004 Nov 01; 32(19):e151. PMID: 15520460; PMCID: PMC528824.
    Citations: 58     Fields:    Translation:AnimalsCells
  19. Aparicio O, Geisberg JV, Struhl K. Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo. Curr Protoc Cell Biol. 2004 Sep; Chapter 17:Unit 17.7. PMID: 18228445.
    Citations: 62     Fields:    Translation:AnimalsCells
  20. Geisberg JV, Struhl K. Cellular stress alters the transcriptional properties of promoter-bound Mot1-TBP complexes. Mol Cell. 2004 May 21; 14(4):479-89. PMID: 15149597.
    Citations: 31     Fields:    Translation:AnimalsCells
  21. Geisberg JV, Moqtaderi Z, Kuras L, Struhl K. Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae. Mol Cell Biol. 2002 Dec; 22(23):8122-34. PMID: 12417716.
    Citations: 37     Fields:    Translation:AnimalsCells
  22. Mencía M, Moqtaderi Z, Geisberg JV, Kuras L, Struhl K. Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast. Mol Cell. 2002 Apr; 9(4):823-33. PMID: 11983173.
    Citations: 77     Fields:    Translation:AnimalsCells
  23. Geisberg JV, Holstege FC, Young RA, Struhl K. Yeast NC2 associates with the RNA polymerase II preinitiation complex and selectively affects transcription in vivo. Mol Cell Biol. 2001 Apr; 21(8):2736-42. PMID: 11283253; PMCID: PMC86904.
    Citations: 41     Fields:    Translation:AnimalsCells
  24. Geisberg JV, Struhl K. TATA-binding protein mutants that increase transcription from enhancerless and repressed promoters in vivo. Mol Cell Biol. 2000 Mar; 20(5):1478-88. PMID: 10669725.
    Citations: 13     Fields:    Translation:AnimalsCells
  25. Mazzarelli JM, Atkins GB, Geisberg JV, Ricciardi RP. The viral oncoproteins Ad5 E1A, HPV16 E7 and SV40 TAg bind a common region of the TBP-associated factor-110. Oncogene. 1995 Nov 02; 11(9):1859-64. PMID: 7478615.
    Citations: 27     Fields:    Translation:HumansCells
  26. Geisberg JV, Chen JL, Ricciardi RP. Subregions of the adenovirus E1A transactivation domain target multiple components of the TFIID complex. Mol Cell Biol. 1995 Nov; 15(11):6283-90. PMID: 7565781.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.