Harvard Catalyst Profiles

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Cornelis Terhorst, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL131093 (HERZOG, ROLAND W.) Jul 1, 2016 - Apr 30, 2020
    NIH/NHLBI
    Enhancing immune regulation in gene therapy for hemophilia
    Role: Co-Principal Investigator
  2. P01AI076210 (TERHORST, CORNELIS P) Jul 5, 2009 - Jun 30, 2014
    NIH/NIAID
    Primary Immuno-Deficiencies Affecting Specific Stages of the Immune Response
    Role: Principal Investigator
  3. R01DK073339 (TERHORST, CORNELIS P) Dec 1, 2005 - Nov 30, 2014
    NIH/NIDDK
    Study of LY108 innate and adaptive immune responses
    Role: Principal Investigator
  4. P01AI065687 (TERHORST, CORNELIS P) Jul 1, 2005 - Jul 31, 2017
    NIH/NIAID
    SLAM Gene Family Controlled Pathways to SLE
    Role: Principal Investigator
  5. P01HL078810 (ERTL, HILDEGUND C. J.) Dec 1, 2004 - Jun 30, 2015
    NIH/NHLBI
    Immune Responses to AAV-Mediated FIX Gene Transfer
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. van Driel B, Wang G, Liao G, Halibozek PJ, Keszei M, O'Keeffe MS, Bhan AK, Wang N, Terhorst C. The cell surface receptor Slamf6 modulates innate immune responses during Citrobacter rodentium-induced colitis. Int Immunol. 2015 Sep; 27(9):447-57. PMID: 25957267.
    Citations: 2     Fields:    Translation:AnimalsCells
  2. Wang N, Halibozek PJ, Yigit B, Zhao H, O'Keeffe MS, Sage P, Sharpe A, Terhorst C. Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors. Front Immunol. 2015; 6:158. PMID: 25926831.
    Citations: 6     
  3. Biswas M, Sarkar D, Kumar SR, Nayak S, Rogers GL, Markusic DM, Liao G, Terhorst C, Herzog RW. Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg. Blood. 2015 May 07; 125(19):2937-47. PMID: 25833958.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  4. Wang G, van Driel BJ, Liao G, O'Keeffe MS, Halibozek PJ, Flipse J, Yigit B, Azcutia V, Luscinskas FW, Wang N, Terhorst C. Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8. PLoS One. 2015; 10(3):e0121968. PMID: 25799045.
    Citations: 8     Fields:    Translation:AnimalsCells
  5. Wang X, Su J, Sherman A, Rogers GL, Liao G, Hoffman BE, Leong KW, Terhorst C, Daniell H, Herzog RW. Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells. Blood. 2015 Apr 09; 125(15):2418-27. PMID: 25700434.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  6. O'Keeffe MS, Song JH, Liao G, De Calisto J, Halibozek PJ, Mora JR, Bhan AK, Wang N, Reinecker HC, Terhorst C. SLAMF4 Is a Negative Regulator of Expansion of Cytotoxic Intraepithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine. Gastroenterology. 2015 May; 148(5):991-1001.e4. PMID: 25678452.
    Citations: 6     Fields:    Translation:AnimalsCells
  7. Jabri B, Terhorst C. Editorial overview: Autoimmunity. Curr Opin Immunol. 2014 Dec; 31:v-vii. PMID: 25456769.
    Citations: 2     Fields:    Translation:HumansAnimals
  8. Sarkar D, Biswas M, Liao G, Seay HR, Perrin GQ, Markusic DM, Hoffman BE, Brusko TM, Terhorst C, Herzog RW. Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia. Mol Ther Methods Clin Dev. 2014 Jul 30; 1. PMID: 25364772.
    Citations: 14     
  9. Sack BK, Herzog RW, Terhorst C, Markusic DM. Development of Gene Transfer for Induction of Antigen-specific Tolerance. Mol Ther Methods Clin Dev. 2014 Apr 30; 1:14013. PMID: 25558460.
    Citations: 27     
  10. De Calisto J, Wang N, Wang G, Yigit B, Engel P, Terhorst C. SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors. Front Immunol. 2014; 5:186. PMID: 24795728.
    Citations: 8     
  11. Liao G, O'Keeffe MS, Wang G, van Driel B, de Waal Malefyt R, Reinecker HC, Herzog RW, Terhorst C. Glucocorticoid-Induced TNF Receptor Family-Related Protein Ligand is Requisite for Optimal Functioning of Regulatory CD4(+) T Cells. Front Immunol. 2014; 5:35. PMID: 24550919.
    Citations: 10     
  12. Chiang HS, Zhao Y, Song JH, Liu S, Wang N, Terhorst C, Sharpe AH, Basavappa M, Jeffrey KL, Reinecker HC. GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses. Nat Immunol. 2014 Jan; 15(1):63-71. PMID: 24270516.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  13. Liao G, van Driel B, Magelky E, O'Keeffe MS, de Waal Malefyt R, Engel P, Herzog RW, Mizoguchi E, Bhan AK, Terhorst C. Glucocorticoid-induced TNF receptor family-related protein ligand regulates the migration of monocytes to the inflamed intestine. FASEB J. 2014 Jan; 28(1):474-84. PMID: 24107315.
    Citations: 7     Fields:    Translation:AnimalsCells
  14. Deng GM, Beltran J, Chen C, Terhorst C, Tsokos GC. T cell CD3? deficiency enables multiorgan tissue inflammation. J Immunol. 2013 Oct 01; 191(7):3563-7. PMID: 23980209.
    Citations: 9     Fields:    Translation:AnimalsCells
  15. de Salort J, Cuenca M, Terhorst C, Engel P, Romero X. Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens. Front Immunol. 2013; 4:225. PMID: 23914190.
    Citations: 8     
  16. Detre C, Yigit B, Keszei M, Castro W, Magelky EM, Terhorst C. SAP modulates B cell functions in a genetic background-dependent manner. Immunol Lett. 2013 Jun; 153(1-2):15-21. PMID: 23806511.
    Citations: 1     Fields:    Translation:AnimalsCells
  17. Keszei M, Detre C, Castro W, Magelky E, O'Keeffe M, Kis-Toth K, Tsokos GC, Wang N, Terhorst C. Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor. FASEB J. 2013 Aug; 27(8):3123-31. PMID: 23629864.
    Citations: 8     Fields:    Translation:AnimalsCells
  18. Martino AT, Basner-Tschakarjan E, Markusic DM, Finn JD, Hinderer C, Zhou S, Ostrov DA, Srivastava A, Ertl HC, Terhorst C, High KA, Mingozzi F, Herzog RW. Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells. Blood. 2013 Mar 21; 121(12):2224-33. PMID: 23325831.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  19. Chang SY, Song JH, Guleng B, Cotoner CA, Arihiro S, Zhao Y, Chiang HS, O'Keeffe M, Liao G, Karp CL, Kweon MN, Sharpe AH, Bhan A, Terhorst C, Reinecker HC. Circulatory antigen processing by mucosal dendritic cells controls CD8(+) T cell activation. Immunity. 2013 Jan 24; 38(1):153-65. PMID: 23246312.
    Citations: 34     Fields:    Translation:AnimalsCells
  20. Sintes J, Cuenca M, Romero X, Bastos R, Terhorst C, Angulo A, Engel P. Cutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells. J Immunol. 2013 Jan 01; 190(1):21-6. PMID: 23225888.
    Citations: 11     Fields:    Translation:AnimalsCells
  21. Wang X, Sherman A, Liao G, Leong KW, Daniell H, Terhorst C, Herzog RW. Mechanism of oral tolerance induction to therapeutic proteins. Adv Drug Deliv Rev. 2013 Jun 15; 65(6):759-73. PMID: 23123293.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  22. Chatterjee M, Hedrich CM, Rauen T, Ioannidis C, Terhorst C, Tsokos GC. CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances ROR?t recruitment to the IL17A promoter in human T lymphocytes. J Biol Chem. 2012 Nov 02; 287(45):38168-77. PMID: 22989874.
    Citations: 6     Fields:    Translation:HumansCells
  23. van Driel B, Liao G, Romero X, O'Keeffe MS, Wang G, Faubion WA, Berger SB, Magelky EM, Manocha M, Azcutia V, Grisham M, Luscinskas FW, Mizoguchi E, de Waal Malefyt R, Reinecker HC, Bhan AK, Wang N, Terhorst C. Signaling lymphocyte activation molecule regulates development of colitis in mice. Gastroenterology. 2012 Dec; 143(6):1544-1554.e7. PMID: 22960654.
    Citations: 9     Fields:    Translation:AnimalsCells
  24. Conway KL, Goel G, Sokol H, Manocha M, Mizoguchi E, Terhorst C, Bhan AK, Gardet A, Xavier RJ. p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation. J Immunol. 2012 Oct 01; 189(7):3631-40. PMID: 22914050.
    Citations: 19     Fields:    Translation:AnimalsCells
  25. Calderón J, Maganto-Garcia E, Punzón C, Carrión J, Terhorst C, Fresno M. The receptor Slamf1 on the surface of myeloid lineage cells controls susceptibility to infection by Trypanosoma cruzi. PLoS Pathog. 2012; 8(7):e1002799. PMID: 22807679.
    Citations: 11     Fields:    Translation:AnimalsCells
  26. Hoffman BE, Ertl HC, Terhorst C, High KA, Herzog RW. Gene therapy research at the frontiers of viral immunology. Front Microbiol. 2012; 3:182. PMID: 22783235.
    Citations: 1     
  27. Detre C, Keszei M, Garrido-Mesa N, Kis-Toth K, Castro W, Agyemang AF, Veerapen N, Besra GS, Carroll MC, Tsokos GC, Wang N, Leadbetter EA, Terhorst C. SAP expression in invariant NKT cells is required for cognate help to support B-cell responses. Blood. 2012 Jul 05; 120(1):122-9. PMID: 22613797.
    Citations: 13     Fields:    Translation:AnimalsCells
  28. Wang G, Abadía-Molina AC, Berger SB, Romero X, O'Keeffe MS, Rojas-Barros DI, Aleman M, Liao G, Maganto-García E, Fresno M, Wang N, Detre C, Terhorst C. Cutting edge: Slamf8 is a negative regulator of Nox2 activity in macrophages. J Immunol. 2012 Jun 15; 188(12):5829-32. PMID: 22593622.
    Citations: 10     Fields:    Translation:AnimalsCells
  29. Ma C, Wang N, Detre C, Wang G, O'Keeffe M, Terhorst C. Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex. J Biol Chem. 2012 May 25; 287(22):18359-65. PMID: 22493499.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  30. Crispín JC, Apostolidis SA, Rosetti F, Keszei M, Wang N, Terhorst C, Mayadas TN, Tsokos GC. Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism. J Immunol. 2012 Apr 15; 188(8):3567-71. PMID: 22422882.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  31. Westerberg LS, Dahlberg C, Baptista M, Moran CJ, Detre C, Keszei M, Eston MA, Alt FW, Terhorst C, Notarangelo LD, Snapper SB. Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function. Blood. 2012 Apr 26; 119(17):3966-74. PMID: 22411869.
    Citations: 29     Fields:    Translation:AnimalsCellsPHPublic Health
  32. Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, Candotti F, Nadeau K, Bouma G, Delmonte OM, Frugoni F, Fomin AB, Buchbinder D, Lundequist EM, Massaad MJ, Tsokos GC, Hartwig J, Manis J, Terhorst C, Geha RS, Snapper S, Lang KS, Malley R, Westerberg L, Thrasher AJ, Notarangelo LD. B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 2012 Mar 22; 119(12):2819-28. PMID: 22302739.
    Citations: 45     Fields:    Translation:AnimalsCells
  33. Chatterjee M, Rauen T, Kis-Toth K, Kyttaris VC, Hedrich CM, Terhorst C, Tsokos GC. Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation. J Immunol. 2012 Feb 01; 188(3):1206-12. PMID: 22184727.
    Citations: 23     Fields:    Translation:HumansCells
  34. Liao G, Detre C, Berger SB, Engel P, de Waal Malefyt R, Herzog RW, Bhan AK, Terhorst C. Glucocorticoid-induced tumor necrosis factor receptor family-related protein regulates CD4(+)T cell-mediated colitis in mice. Gastroenterology. 2012 Mar; 142(3):582-591.e8. PMID: 22155173.
    Citations: 9     Fields:    Translation:AnimalsCells
  35. West EE, Youngblood B, Tan WG, Jin HT, Araki K, Alexe G, Konieczny BT, Calpe S, Freeman GJ, Terhorst C, Haining WN, Ahmed R. Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity. 2011 Aug 26; 35(2):285-98. PMID: 21856186.
    Citations: 72     Fields:    Translation:AnimalsCells
  36. Lányi Á, Baráth M, Péterfi Z, Bogel G, Orient A, Simon T, Petrovszki E, Kis-Tóth K, Sirokmány G, Rajnavölgyi É, Terhorst C, Buday L, Geiszt M. The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading. PLoS One. 2011; 6(8):e23653. PMID: 21886807.
    Citations: 11     Fields:    Translation:HumansCells
  37. Brown DR, Calpe S, Keszei M, Wang N, McArdel S, Terhorst C, Sharpe AH. Cutting edge: an NK cell-independent role for Slamf4 in controlling humoral autoimmunity. J Immunol. 2011 Jul 01; 187(1):21-5. PMID: 21622868.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  38. Keszei M, Detre C, Rietdijk ST, Muñoz P, Romero X, Berger SB, Calpe S, Liao G, Castro W, Julien A, Wu YY, Shin DM, Sancho J, Zubiaur M, Morse HC, Morel L, Engel P, Wang N, Terhorst C. A novel isoform of the Ly108 gene ameliorates murine lupus. J Exp Med. 2011 Apr 11; 208(4):811-22. PMID: 21422172.
    Citations: 28     Fields:    Translation:AnimalsCells
  39. Hoffman BE, Martino AT, Sack BK, Cao O, Liao G, Terhorst C, Herzog RW. Nonredundant roles of IL-10 and TGF-ß in suppression of immune responses to hepatic AAV-factor IX gene transfer. Mol Ther. 2011 Jul; 19(7):1263-72. PMID: 21386826.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  40. Keszei M, Latchman YE, Vanguri VK, Brown DR, Detre C, Morra M, Arancibia-Carcamo CV, Arancibia CV, Paul E, Calpe S, Castro W, Wang N, Terhorst C, Sharpe AH. Auto-antibody production and glomerulonephritis in congenic Slamf1-/- and Slamf2-/- [B6.129] but not in Slamf1-/- and Slamf2-/- [BALB/c.129] mice. Int Immunol. 2011 Feb; 23(2):149-58. PMID: 21278219.
    Citations: 10     Fields:    Translation:HumansAnimals
  41. Chatterjee M, Kis-Toth K, Thai TH, Terhorst C, Tsokos GC. SLAMF6-driven co-stimulation of human peripheral T cells is defective in SLE T cells. Autoimmunity. 2011 May; 44(3):211-8. PMID: 21231893.
    Citations: 14     Fields:    Translation:HumansCells
  42. Wang N, Calpe S, Westcott J, Castro W, Ma C, Engel P, Schatzle JD, Terhorst C. Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. J Immunol. 2010 Nov 15; 185(10):5683-7. PMID: 20962259.
    Citations: 19     Fields:    Translation:AnimalsCells
  43. Berger SB, Romero X, Ma C, Wang G, Faubion WA, Liao G, Compeer E, Keszei M, Rameh L, Wang N, Boes M, Regueiro JR, Reinecker HC, Terhorst C. SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages. Nat Immunol. 2010 Oct; 11(10):920-7. PMID: 20818396.
    Citations: 62     Fields:    Translation:AnimalsCells
  44. Sintes J, Romero X, de Salort J, Terhorst C, Engel P. Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages. J Leukoc Biol. 2010 Oct; 88(4):687-97. PMID: 20628063.
    Citations: 8     Fields:    Translation:AnimalsCells
  45. Walter JE, Rucci F, Patrizi L, Recher M, Regenass S, Paganini T, Keszei M, Pessach I, Lang PA, Poliani PL, Giliani S, Al-Herz W, Cowan MJ, Puck JM, Bleesing J, Niehues T, Schuetz C, Malech H, DeRavin SS, Facchetti F, Gennery AR, Andersson E, Kamani NR, Sekiguchi J, Alenezi HM, Chinen J, Dbaibo G, ElGhazali G, Fontana A, Pasic S, Detre C, Terhorst C, Alt FW, Notarangelo LD. Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency. J Exp Med. 2010 Jul 05; 207(7):1541-54. PMID: 20547827.
    Citations: 33     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  46. Crispín JC, Kyttaris VC, Terhorst C, Tsokos GC. T cells as therapeutic targets in SLE. Nat Rev Rheumatol. 2010 Jun; 6(6):317-25. PMID: 20458333.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  47. Porcelli S, Brenner MB, Greenstein JL, Terhorst C, Balk SP, Bleicher PA. Recognition of Cluster of Differentiation 1 Antigens by Human CD4-CD8- CytolyticT Lymphocyte. Nature. 1989. 341: 447-450. 1989. J Immunol. 2010 Apr 01; 184(7):3306-9. PMID: 20304831.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  48. Detre C, Keszei M, Romero X, Tsokos GC, Terhorst C. SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin Immunopathol. 2010 Jun; 32(2):157-71. PMID: 20146065.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  49. Liao G, Nayak S, Regueiro JR, Berger SB, Detre C, Romero X, de Waal Malefyt R, Chatila TA, Herzog RW, Terhorst C. GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells. Int Immunol. 2010 Apr; 22(4):259-70. PMID: 20139172.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  50. Rucci F, Notarangelo LD, Fazeli A, Patrizi L, Hickernell T, Paganini T, Coakley KM, Detre C, Keszei M, Walter JE, Feldman L, Cheng HL, Poliani PL, Wang JH, Balter BB, Recher M, Andersson EM, Zha S, Giliani S, Terhorst C, Alt FW, Yan CT. Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3024-9. PMID: 20133615.
    Citations: 15     Fields:    Translation:HumansAnimals
  51. Diamond B, Cunningham-Rundles C, Fischer A, Geha R, Notarangelo L, Ochs H, Rotrosen D, Terhorst C. Josiah F. Wedgwood (1950-2009). J Allergy Clin Immunol. 2010 Feb; 125(2):506. PMID: 20042229.
    Citations:    Fields:    
  52. Martino AT, Nayak S, Hoffman BE, Cooper M, Liao G, Markusic DM, Byrne BJ, Terhorst C, Herzog RW. Tolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicity. PLoS One. 2009 Aug 04; 4(8):e6376. PMID: 19652717.
    Citations: 26     Fields:    Translation:AnimalsCells
  53. Cooper M, Nayak S, Hoffman BE, Terhorst C, Cao O, Herzog RW. Improved induction of immune tolerance to factor IX by hepatic AAV-8 gene transfer. Hum Gene Ther. 2009 Jul; 20(7):767-76. PMID: 19309290.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  54. Manocha M, Rietdijk S, Svend R, Laouar A, Liao G, Bhan A, Borst J, Borst J, Terhorst C, Manjunath N. Blocking CD27-CD70 costimulatory pathway suppresses experimental colitis. J Immunol. 2009 Jul 01; 183(1):270-6. PMID: 19525396.
    Citations: 11     Fields:    Translation:AnimalsCells
  55. Sintes J, Romero X, Marin P, Terhorst C, Engel P. Differential expression of CD150 (SLAM) family receptors by human hematopoietic stem and progenitor cells. Exp Hematol. 2008 Sep; 36(9):1199-204. PMID: 18495325.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  56. Maganto-Garcia E, Punzon C, Terhorst C, Fresno M. Rab5 activation by Toll-like receptor 2 is required for Trypanosoma cruzi internalization and replication in macrophages. Traffic. 2008 Aug; 9(8):1299-315. PMID: 18445119.
    Citations: 15     Fields:    Translation:AnimalsCells
  57. Calpe S, Wang N, Romero X, Berger SB, Lanyi A, Engel P, Terhorst C. The SLAM and SAP gene families control innate and adaptive immune responses. Adv Immunol. 2008; 97:177-250. PMID: 18501771.
    Citations: 62     Fields:    Translation:HumansAnimals
  58. Li W, Sofi MH, Rietdijk S, Wang N, Terhorst C, Chang CH. The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction. Immunity. 2007 Nov; 27(5):763-74. PMID: 18031696.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  59. Griewank K, Borowski C, Rietdijk S, Wang N, Julien A, Wei DG, Mamchak AA, Terhorst C, Bendelac A. Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity. 2007 Nov; 27(5):751-62. PMID: 18031695.
    Citations: 139     Fields:    Translation:AnimalsCells
  60. Cao O, Dobrzynski E, Wang L, Nayak S, Mingle B, Terhorst C, Herzog RW. Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer. Blood. 2007 Aug 15; 110(4):1132-40. PMID: 17438084.
    Citations: 100     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  61. Chen G, Tai AK, Lin M, Chang F, Terhorst C, Huber BT. Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death. Eur J Immunol. 2007 Mar; 37(3):663-74. PMID: 17266174.
    Citations: 17     Fields:    Translation:AnimalsCells
  62. Fernández-Malavé E, Wang N, Pulgar M, Schamel WW, Alarcón B, Terhorst C. Overlapping functions of human CD3delta and mouse CD3gamma in alphabeta T-cell development revealed in a humanized CD3gamma-mouse. Blood. 2006 Nov 15; 108(10):3420-7. PMID: 16888097.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  63. Wang N, Campo M, Ting L, Fleming C, Terhorst C, Finn PW. The costimulatory molecule SLAM is critical for pulmonary allergic responses. Am J Respir Cell Mol Biol. 2006 Aug; 35(2):206-10. PMID: 16528012.
    Citations: 2     Fields:    Translation:AnimalsCells
  64. Calpe S, Erdos E, Liao G, Wang N, Rietdijk S, Simarro M, Scholtz B, Mooney J, Lee CH, Shin MS, Rajnavölgyi E, Schatzle J, Morse HC, Terhorst C, Lanyi A. Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters. Immunogenetics. 2006 Feb; 58(1):15-25. PMID: 16425036.
    Citations: 9     Fields:    Translation:AnimalsCells
  65. Abadía-Molina AC, Ji H, Faubion WA, Julien A, Latchman Y, Yagita H, Sharpe A, Bhan AK, Terhorst C. CD48 controls T-cell and antigen-presenting cell functions in experimental colitis. Gastroenterology. 2006 Feb; 130(2):424-34. PMID: 16472597.
    Citations: 12     Fields:    Translation:AnimalsCells
  66. Réthi B, Gogolák P, Szatmari I, Veres A, Erdôs E, Nagy L, Rajnavölgyi E, Terhorst C, Lányi A. SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells. Blood. 2006 Apr 01; 107(7):2821-9. PMID: 16317102.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  67. Laroux FS, Romero X, Wetzler L, Engel P, Terhorst C. Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria. J Immunol. 2005 Nov 01; 175(9):5596-600. PMID: 16237045.
    Citations: 62     Fields:    Translation:AnimalsCells
  68. Chen G, Tai AK, Lin M, Chang F, Terhorst C, Huber BT. Signaling lymphocyte activation molecule-associated protein is a negative regulator of the CD8 T cell response in mice. J Immunol. 2005 Aug 15; 175(4):2212-8. PMID: 16081788.
    Citations: 13     Fields:    Translation:AnimalsCells
  69. Nanda N, Andre P, Bao M, Clauser K, Deguzman F, Howie D, Conley PB, Terhorst C, Phillips DR. Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling. Blood. 2005 Nov 01; 106(9):3028-34. PMID: 16037392.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  70. Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005 Jul 01; 121(7):1109-21. PMID: 15989959.
    Citations: 1055     Fields:    Translation:AnimalsCells
  71. Howie D, Laroux FS, Morra M, Satoskar AR, Rosas LE, Faubion WA, Julien A, Rietdijk S, Coyle AJ, Fraser C, Terhorst C. Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J Immunol. 2005 May 15; 174(10):5931-5. PMID: 15879084.
    Citations: 25     Fields:    Translation:AnimalsCells
  72. Abadía-Molina AC, Mizoguchi A, Faubion WA, De Jong YP, Rietdijk ST, Comiskey M, Clarke K, Bhan AK, Terhorst C. In vivo generation of oligoclonal colitic CD4+ T-cell lines expressing a distinct T-cell receptor Vbeta. Gastroenterology. 2005 May; 128(5):1268-77. PMID: 15887110.
    Citations: 1     Fields:    Translation:AnimalsCells
  73. Morra M, Barrington RA, Abadia-Molina AC, Okamoto S, Julien A, Gullo C, Kalsy A, Edwards MJ, Chen G, Spolski R, Leonard WJ, Huber BT, Borrow P, Biron CA, Satoskar AR, Carroll MC, Terhorst C. Defective B cell responses in the absence of SH2D1A. Proc Natl Acad Sci U S A. 2005 Mar 29; 102(13):4819-23. PMID: 15774582.
    Citations: 23     Fields:    Translation:AnimalsCells
  74. Chung B, Aoukaty A, Dutz J, Terhorst C, Tan R. Signaling lymphocytic activation molecule-associated protein controls NKT cell functions. J Immunol. 2005 Mar 15; 174(6):3153-7. PMID: 15749842.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  75. Vyse TJ, Richardson AM, Walsh E, Farwell L, Daly MJ, Terhorst C, Rioux JD. Mapping autoimmune disease genes in humans: lessons from IBD and SLE. Novartis Found Symp. 2005; 267:94-107; discussion 107-12. PMID: 15999803.
    Citations: 3     Fields:    Translation:Humans
  76. Okamoto S, Ji H, Howie D, Clarke K, Gullo C, Manning S, Coyle AJ, Terhorst C. Expression of the SH2D1A gene is regulated by a combination of transcriptional and post-transcriptional mechanisms. Eur J Immunol. 2004 Nov; 34(11):3176-86. PMID: 15459902.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  77. Roda-Navarro P, Mittelbrunn M, Ortega M, Howie D, Terhorst C, Sánchez-Madrid F, Fernández-Ruiz E. Dynamic redistribution of the activating 2B4/SAP complex at the cytotoxic NK cell immune synapse. J Immunol. 2004 Sep 15; 173(6):3640-6. PMID: 15356108.
    Citations: 15     Fields:    Translation:HumansCells
  78. Schmidt-Supprian M, Tian J, Ji H, Terhorst C, Bhan AK, Grant EP, Pasparakis M, Casola S, Coyle AJ, Rajewsky K. I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion. J Immunol. 2004 Aug 01; 173(3):1612-9. PMID: 15265889.
    Citations: 13     Fields:    Translation:AnimalsCellsPHPublic Health
  79. Hokama A, Mizoguchi E, Sugimoto K, Shimomura Y, Tanaka Y, Yoshida M, Rietdijk ST, de Jong YP, Snapper SB, Terhorst C, Blumberg RS, Mizoguchi A. Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation. Immunity. 2004 Jun; 20(6):681-93. PMID: 15189734.
    Citations: 33     Fields:    Translation:AnimalsCells
  80. Faubion WA, De Jong YP, Molina AA, Ji H, Clarke K, Wang B, Mizoguchi E, Simpson SJ, Bhan AK, Terhorst C. Colitis is associated with thymic destruction attenuating CD4+25+ regulatory T cells in the periphery. Gastroenterology. 2004 Jun; 126(7):1759-70. PMID: 15188171.
    Citations: 19     Fields:    Translation:AnimalsCells
  81. Ji HB, Liao G, Faubion WA, Abadía-Molina AC, Cozzo C, Laroux FS, Caton A, Terhorst C. Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression. J Immunol. 2004 May 15; 172(10):5823-7. PMID: 15128759.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  82. Wang N, Satoskar A, Faubion W, Howie D, Okamoto S, Feske S, Gullo C, Clarke K, Sosa MR, Sharpe AH, Terhorst C. The cell surface receptor SLAM controls T cell and macrophage functions. J Exp Med. 2004 May 03; 199(9):1255-64. PMID: 15123745.
    Citations: 54     Fields:    Translation:AnimalsCells
  83. Simarro M, Lanyi A, Howie D, Poy F, Bruggeman J, Choi M, Sumegi J, Eck MJ, Terhorst C. SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9. Int Immunol. 2004 May; 16(5):727-36. PMID: 15096483.
    Citations: 18     Fields:    Translation:AnimalsCells
  84. de Jong YP, Rietdijk ST, Faubion WA, Abadia-Molina AC, Clarke K, Mizoguchi E, Tian J, Delaney T, Manning S, Gutierrez-Ramos JC, Bhan AK, Coyle AJ, Terhorst C. Blocking inducible co-stimulator in the absence of CD28 impairs Th1 and CD25+ regulatory T cells in murine colitis. Int Immunol. 2004 Feb; 16(2):205-13. PMID: 14734605.
    Citations: 12     Fields:    Translation:AnimalsCells
  85. Nagler-Anderson C, Bhan AK, Podolsky DK, Terhorst C. Control freaks: immune regulatory cells. Nat Immunol. 2004 Feb; 5(2):119-22. PMID: 14749778.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  86. Engel P, Eck MJ, Terhorst C. The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease. Nat Rev Immunol. 2003 Oct; 3(10):813-21. PMID: 14523387.
    Citations: 71     Fields:    Translation:HumansAnimalsCells
  87. Chan B, Lanyi A, Song HK, Griesbach J, Simarro-Grande M, Poy F, Howie D, Sumegi J, Terhorst C, Eck MJ. SAP couples Fyn to SLAM immune receptors. Nat Cell Biol. 2003 Feb; 5(2):155-60. PMID: 12545174.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  88. Mizoguchi A, Mizoguchi E, de Jong YP, Takedatsu H, Preffer FI, Terhorst C, Bhan AK. Role of the CD5 molecule on TCR gammadelta T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation. Int Immunol. 2003 Jan; 15(1):97-108. PMID: 12502730.
    Citations: 12     Fields:    Translation:AnimalsCells
  89. Howie D, Okamoto S, Rietdijk S, Clarke K, Wang N, Gullo C, Bruggeman JP, Manning S, Coyle AJ, Greenfield E, Kuchroo V, Terhorst C. The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production. Blood. 2002 Oct 15; 100(8):2899-907. PMID: 12351401.
    Citations: 21     Fields:    Translation:AnimalsCells
  90. Ji HB, Gupta A, Okamoto S, Blum MD, Tan L, Goldring MB, Lacy E, Roy AL, Terhorst C. T cell-specific expression of the murine CD3delta promoter. J Biol Chem. 2002 Dec 06; 277(49):47898-906. PMID: 12324448.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  91. Parolini O, Kagerbauer B, Simonitsch-Klupp I, Ambros P, Jaeger U, Mann G, Haas OA, Morra M, Gadner H, Terhorst C, Knapp W, Holter W. Analysis of SH2D1A mutations in patients with severe Epstein-Barr virus infections, Burkitt's lymphoma, and Hodgkin's lymphoma. Ann Hematol. 2002 Aug; 81(8):441-7. PMID: 12224001.
    Citations: 5     Fields:    Translation:HumansCells
  92. Tovar V, del Valle J, Zapater N, Martin M, Romero X, Pizcueta P, Bosch J, Terhorst C, Engel P. Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors. Immunogenetics. 2002 Sep; 54(6):394-402. PMID: 12242590.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  93. Sumegi J, Seemayer TA, Huang D, Davis JR, Morra M, Gross TG, Yin L, Romco G, Klein E, Terhorst C, Lanyi A. A spectrum of mutations in SH2D1A that causes X-linked lymphoproliferative disease and other Epstein-Barr virus-associated illnesses. Leuk Lymphoma. 2002 Jun; 43(6):1189-201. PMID: 12152986.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  94. Guirado M, de Aós I, Orta T, Rivas L, Terhorst C, Zubiaur M, Sancho J. Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells. Biochem Biophys Res Commun. 2002 Mar 01; 291(3):574-81. PMID: 11855827.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  95. Hwang PM, Li C, Morra M, Lillywhite J, Muhandiram DR, Gertler F, Terhorst C, Kay LE, Pawson T, Forman-Kay JD, Li SC. A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome. EMBO J. 2002 Feb 01; 21(3):314-23. PMID: 11823424.
    Citations: 23     Fields:    Translation:HumansCells
  96. Howie D, Simarro M, Sayos J, Guirado M, Sancho J, Terhorst C. Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation. Blood. 2002 Feb 01; 99(3):957-65. PMID: 11806999.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  97. Fraser CC, Howie D, Morra M, Qiu Y, Murphy C, Shen Q, Gutierrez-Ramos JC, Coyle A, Kingsbury GA, Terhorst C. Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family. Immunogenetics. 2002 Feb; 53(10-11):843-50. PMID: 11862385.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  98. Mizoguchi E, Mizoguchi A, Takedatsu H, Cario E, de Jong YP, Ooi CJ, Xavier RJ, Terhorst C, Podolsky DK, Bhan AK. Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice. Gastroenterology. 2002 Jan; 122(1):134-44. PMID: 11781288.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  99. Morra M, Lu J, Poy F, Martin M, Sayos J, Calpe S, Gullo C, Howie D, Rietdijk S, Thompson A, Coyle AJ, Denny C, Yaffe MB, Engel P, Eck MJ, Terhorst C. Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells. EMBO J. 2001 Nov 01; 20(21):5840-52. PMID: 11689425.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  100. Sohn KJ, Shah SA, Reid S, Choi M, Carrier J, Comiskey M, Terhorst C, Kim YI. Molecular genetics of ulcerative colitis-associated colon cancer in the interleukin 2- and beta(2)-microglobulin-deficient mouse. Cancer Res. 2001 Sep 15; 61(18):6912-7. PMID: 11559569.
    Citations: 7     Fields:    Translation:AnimalsCells
  101. Morra M, Silander O, Calpe S, Choi M, Oettgen H, Myers L, Etzioni A, Buckley R, Terhorst C. Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome. Blood. 2001 Sep 01; 98(5):1321-5. PMID: 11520777.
    Citations: 20     Fields:    Translation:HumansCells
  102. Morra M, Simarro-Grande M, Martin M, Chen AS, Lanyi A, Silander O, Calpe S, Davis J, Pawson T, Eck MJ, Sumegi J, Engel P, Li SC, Terhorst C. Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients. J Biol Chem. 2001 Sep 28; 276(39):36809-16. PMID: 11477068.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  103. Wang N, Morra M, Wu C, Gullo C, Howie D, Coyle T, Engel P, Terhorst C. CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells. Immunogenetics. 2001 Jul; 53(5):382-94. PMID: 11486275.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  104. Sayós J, Martín M, Chen A, Simarro M, Howie D, Morra M, Engel P, Terhorst C. Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP. Blood. 2001 Jun 15; 97(12):3867-74. PMID: 11389028.
    Citations: 17     Fields:    Translation:HumansCells
  105. Wu C, Nguyen KB, Pien GC, Wang N, Gullo C, Howie D, Sosa MR, Edwards MJ, Borrow P, Satoskar AR, Sharpe AH, Biron CA, Terhorst C. SAP controls T cell responses to virus and terminal differentiation of TH2 cells. Nat Immunol. 2001 May; 2(5):410-4. PMID: 11323694.
    Citations: 71     Fields:    Translation:AnimalsCells
  106. Veltkamp C, Tonkonogy SL, De Jong YP, Albright C, Grenther WB, Balish E, Terhorst C, Sartor RB. Continuous stimulation by normal luminal bacteria is essential for the development and perpetuation of colitis in Tg(epsilon26) mice. Gastroenterology. 2001 Mar; 120(4):900-13. PMID: 11231944.
    Citations: 33     Fields:    Translation:AnimalsCells
  107. Morra M, Howie D, Grande MS, Sayos J, Wang N, Wu C, Engel P, Terhorst C. X-linked lymphoproliferative disease: a progressive immunodeficiency. Annu Rev Immunol. 2001; 19:657-82. PMID: 11244050.
    Citations: 34     Fields:    Translation:HumansCells
  108. Nelson DL, Terhorst C. X-linked lymphoproliferative syndrome. Clin Exp Immunol. 2000 Dec; 122(3):291-5. PMID: 11122230.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  109. Sayós J, Nguyen KB, Wu C, Stepp SE, Howie D, Schatzle JD, Kumar V, Biron CA, Terhorst C. Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4. Int Immunol. 2000 Dec; 12(12):1749-57. PMID: 11099315.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  110. De Jong YP, Comiskey M, Kalled SL, Mizoguchi E, Flavell RA, Bhan AK, Terhorst C. Chronic murine colitis is dependent on the CD154/CD40 pathway and can be attenuated by anti-CD154 administration. Gastroenterology. 2000 Sep; 119(3):715-23. PMID: 10982766.
    Citations: 19     Fields:    Translation:AnimalsCells
  111. Wu C, Sayos J, Wang N, Howie D, Coyle A, Terhorst C. Genomic organization and characterization of mouse SAP, the gene that is altered in X-linked lymphoproliferative disease. Immunogenetics. 2000 Aug; 51(10):805-15. PMID: 10970095.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  112. Howie D, Sayos J, Terhorst C, Morra M. The gene defective in X-linked lymphoproliferative disease controls T cell dependent immune surveillance against Epstein-Barr virus. Curr Opin Immunol. 2000 Aug; 12(4):474-8. PMID: 10899030.
    Citations: 6     Fields:    Translation:HumansCells
  113. Saubermann LJ, Beck P, De Jong YP, Pitman RS, Ryan MS, Kim HS, Exley M, Snapper S, Balk SP, Hagen SJ, Kanauchi O, Motoki K, Sakai T, Terhorst C, Koezuka Y, Podolsky DK, Blumberg RS. Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice. Gastroenterology. 2000 Jul; 119(1):119-28. PMID: 10889161.
    Citations: 48     Fields:    Translation:AnimalsCells
  114. van Ewijk W, Holländer G, Terhorst C, Wang B. Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsets. Development. 2000 Apr; 127(8):1583-91. PMID: 10725235.
    Citations: 51     Fields:    Translation:AnimalsCells
  115. Simpson SJ, de Jong YP, Comiskey M, Terhorst C. Pathways of T cell pathology in models of chronic intestinal inflammation. Int Rev Immunol. 2000; 19(1):1-37. PMID: 10723675.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  116. Satoskar AR, Stamm LM, Zhang X, Okano M, David JR, Terhorst C, Wang B. NK cell-deficient mice develop a Th1-like response but fail to mount an efficient antigen-specific IgG2a antibody response. J Immunol. 1999 Nov 15; 163(10):5298-302. PMID: 10553052.
    Citations: 8     Fields:    Translation:AnimalsCells
  117. Poy F, Yaffe MB, Sayos J, Saxena K, Morra M, Sumegi J, Cantley LC, Terhorst C, Eck MJ. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition. Mol Cell. 1999 Oct; 4(4):555-61. PMID: 10549287.
    Citations: 48     Fields:    Translation:HumansCells
  118. Zubiaur M, Guirado M, Terhorst C, Malavasi F, Sancho J. The CD3-gamma delta epsilon transducing module mediates CD38-induced protein-tyrosine kinase and mitogen-activated protein kinase activation in Jurkat T cells. J Biol Chem. 1999 Jul 16; 274(29):20633-42. PMID: 10400695.
    Citations: 4     Fields:    Translation:HumansCells
  119. Satoskar AR, Stamm LM, Zhang X, Satoskar AA, Okano M, Terhorst C, David JR, Wang B. Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infection. J Immunol. 1999 Jun 01; 162(11):6747-54. PMID: 10352294.
    Citations: 13     Fields:    Translation:AnimalsCells
  120. Levelt CN, de Jong YP, Mizoguchi E, O'Farrelly C, Bhan AK, Tonegawa S, Terhorst C, Simpson SJ. High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytes. Proc Natl Acad Sci U S A. 1999 May 11; 96(10):5628-33. PMID: 10318935.
    Citations: 12     Fields:    Translation:AnimalsCells
  121. She J, Ruzek MC, Velupillai P, de Aos I, Wang B, Harn DA, Sancho J, Biron CA, Terhorst C. Generation of antigen-specific cytotoxic T lymphocytes and regulation of cytokine production takes place in the absence of CD3zeta. Int Immunol. 1999 May; 11(5):845-57. PMID: 10330289.
    Citations: 1     Fields:    Translation:AnimalsCells
  122. Wang B, Wang N, Whitehurst CE, She J, Chen J, Terhorst C. T lymphocyte development in the absence of CD3 epsilon or CD3 gamma delta epsilon zeta. J Immunol. 1999 Jan 01; 162(1):88-94. PMID: 9886373.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  123. Wang N, Wang B, Salio M, Allen D, She J, Terhorst C. Expression of a CD3 epsilon transgene in CD3 epsilon(null) mice does not restore CD3 gamma and delta expression but efficiently rescues T cell development from a subpopulation of prothymocytes. Int Immunol. 1998 Dec; 10(12):1777-88. PMID: 9885898.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  124. Gold DP, Clevers H, Alarcon B, Dunlap S, Novotny J, Williams AF, Terhorst C. Evolutionary relationship between the T3 chains of the T-cell receptor complex and the immunoglobulin supergene family. Proc Natl Acad Sci U S A. 1987 Nov; 84(21):7649-53. PMID: 3478717.
    Citations: 33     Fields:    Translation:AnimalsCells
  125. Biron CA, van den Elsen P, Tutt MM, Medveczky P, Kumar V, Terhorst C. Murine natural killer cells stimulated in vivo do not express the T cell receptor alpha, beta, gamma, T3 delta, or T3 epsilon genes. J Immunol. 1987 Sep 01; 139(5):1704-10. PMID: 3497976.
    Citations: 18     Fields:    Translation:AnimalsCells
  126. Alarcon B, De Vries J, Pettey C, Boylston A, Yssel H, Terhorst C, Spits H. The T-cell receptor gamma chain-CD3 complex: implication in the cytotoxic activity of a CD3+ CD4- CD8- human natural killer clone. Proc Natl Acad Sci U S A. 1987 Jun; 84(11):3861-5. PMID: 3108883.
    Citations: 8     Fields:    Translation:HumansCells
  127. Pettey CL, Alarcon B, Malin R, Weinberg K, Terhorst C. T3-p28 is a protein associated with the delta and epsilon chains of the T cell receptor-T3 antigen complex during biosynthesis. J Biol Chem. 1987 Apr 05; 262(10):4854-9. PMID: 2951373.
    Citations: 10     Fields:    Translation:HumansCells
  128. Umetsu DT, Katzen D, Chatila T, Miller R, Jabara HH, Maher M, Oettgen H, Terhorst C, Geha RS. Requirements for activation of human peripheral blood T cells by mouse monoclonal antibodies to CD3. Clin Immunol Immunopathol. 1987 Apr; 43(1):48-64. PMID: 3103959.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  129. Oettgen HC, Terhorst C. The T-cell receptor-T3 complex and T-lymphocyte activation. Hum Immunol. 1987 Mar; 18(3):187-204. PMID: 2952627.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  130. Gold DP, van Dongen JJ, Morton CC, Bruns GA, van den Elsen P, Geurts van Kessel AH, Terhorst C. The gene encoding the epsilon subunit of the T3/T-cell receptor complex maps to chromosome 11 in humans and to chromosome 9 in mice. Proc Natl Acad Sci U S A. 1987 Mar; 84(6):1664-8. PMID: 2882512.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  131. Oettgen HC, Terhorst C. A review of the structure and function of the T-cell receptor-T3 complex. Crit Rev Immunol. 1987; 7(2):131-67. PMID: 2953555.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  132. Reiser H, Oettgen H, Yeh ET, Terhorst C, Low MG, Benacerraf B, Rock KL. Structural characterization of the TAP molecule: a phosphatidylinositol-linked glycoprotein distinct from the T cell receptor/T3 complex and Thy-1. Cell. 1986 Nov 07; 47(3):365-70. PMID: 2876780.
    Citations: 34     Fields:    Translation:HumansCells
  133. Furley AJ, Reeves BR, Mizutani S, Altass LJ, Watt SM, Jacob MC, van den Elsen P, Terhorst C, Greaves MF. Divergent molecular phenotypes of KG1 and KG1a myeloid cell lines. Blood. 1986 Nov; 68(5):1101-7. PMID: 3094604.
    Citations: 25     Fields:    Translation:HumansCells
  134. MacLeod CL, Minning L, Gold DP, Terhorst C, Wilkinson M. Negative trans-regulation of T-cell antigen receptor/T3 complex mRNA expression in murine T-lymphoma somatic cell hybrids. Proc Natl Acad Sci U S A. 1986 Sep; 83(18):6989-93. PMID: 3092223.
    Citations: 8     Fields:    Translation:AnimalsCells
  135. Gold DP, Puck JM, Pettey CL, Cho M, Coligan J, Woody JN, Terhorst C. Isolation of cDNA clones encoding the 20K non-glycosylated polypeptide chain of the human T-cell receptor/T3 complex. Nature. 1986 May 22-28; 321(6068):431-4. PMID: 3012357.
    Citations: 46     Fields:    Translation:HumansCells
  136. van den Elsen P, Georgopoulos K, Shepley BA, Orkin S, Terhorst C. Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex. Proc Natl Acad Sci U S A. 1986 May; 83(9):2944-8. PMID: 2939461.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  137. Spits H, van Schooten W, Keizer H, van Seventer G, van de Rijn M, Terhorst C, de Vries JE. Alloantigen recognition is preceded by nonspecific adhesion of cytotoxic T cells and target cells. Science. 1986 Apr 18; 232(4748):403-5. PMID: 3485822.
    Citations: 28     Fields:    Translation:HumansCells
  138. Oettgen HC, Pettey CL, Maloy WL, Terhorst C. A T3-like protein complex associated with the antigen receptor on murine T cells. Nature. 1986 Mar 20-26; 320(6059):272-5. PMID: 2938011.