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David P. White, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P50HL060292 (SAPER, CLIFFORD) Sep 1, 1998 - Aug 31, 2008
    NIH/NHLBI
    Harvard Center on Sleep Neurobiology and Sleep Apnea (SCOR)
    Role: Co-Principal Investigator
  2. R01HL048531 (WHITE, DAVID P.) Jul 20, 1992 - Jun 30, 2011
    NIH/NHLBI
    Defining Phenotypic Traits in Obstructive Sleep Apnea
    Role: Principal Investigator
  3. M01RR002635 (GOTTLIEB, GARY L) Dec 1, 1984 - Mar 31, 2010
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator
  4. K08HL001316 (WHITE, DAVID P.) Jul 1, 1984 - Jun 30, 1989
    NIH/NHLBI
    HYPOPHARYNX, METABOLISM, AND BREATHING DURING SLEEP
    Role: Principal Investigator
  5. M01RR001032 (SUKHATME, VIKAS P) Dec 1, 1977 - Mar 31, 2010
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, Eckert DJ, White DP, Wellman A. The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial. Am J Respir Crit Care Med. 2018 Nov 05. PMID: 30395486.
    Citations:    Fields:    
  2. Azarbarzin A, Sands SA, Stone KL, Taranto-Montemurro L, Messineo L, Terrill PI, Ancoli-Israel S, Ensrud K, Purcell S, White DP, Redline S, Wellman A. The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study. Eur Heart J. 2018 Oct 30. PMID: 30376054.
    Citations:    Fields:    
  3. Sands SA, Edwards BA, Terrill PI, Butler JP, Owens RL, Taranto-Montemurro L, Azarbarzin A, Marques M, Hess LB, Smales ET, de Melo CM, White DP, Malhotra A, Wellman A. Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy. Eur Respir J. 2018 Sep; 52(3). PMID: 30139771.
    Citations:    Fields:    
  4. Taranto-Montemurro L, Sands SA, Grace KP, Azarbarzin A, Messineo L, Salant R, White DP, Wellman DA. Neural memory of the genioglossus muscle during sleep is stage-dependent in healthy subjects and obstructive sleep apnoea patients. J Physiol. 2018 Nov; 596(21):5163-5173. PMID: 30022493.
    Citations: 1     Fields:    
  5. Messineo L, Taranto-Montemurro L, Azarbarzin A, Oliveira Marques MD, Calianese N, White DP, Wellman A, Sands SA. Breath-holding as a means to estimate the loop gain contribution to obstructive sleep apnoea. J Physiol. 2018 Sep; 596(17):4043-4056. PMID: 29882226.
    Citations: 1     Fields:    
  6. Marques M, Genta PR, Azarbarzin A, Sands SA, Taranto-Montemurro L, Messineo L, White DP, Wellman A. Retropalatal and retroglossal airway compliance in patients with obstructive sleep apnea. Respir Physiol Neurobiol. 2018 12; 258:98-103. PMID: 29913264.
    Citations:    Fields:    
  7. Sands SA, Edwards BA, Terrill PI, Taranto-Montemurro L, Azarbarzin A, Marques M, Hess LB, White DP, Wellman A. Phenotyping Pharyngeal Pathophysiology using Polysomnography in Patients with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2018 May 01; 197(9):1187-1197. PMID: 29327943.
    Citations: 2     Fields:    
  8. Azarbarzin A, Sands SA, Marques M, Genta PR, Taranto-Montemurro L, Messineo L, White DP, Wellman A. Palatal prolapse as a signature of expiratory flow limitation and inspiratory palatal collapse in patients with obstructive sleep apnoea. Eur Respir J. 2018 02; 51(2). PMID: 29444914.
    Citations:    Fields:    
  9. Sands SA, Terrill PI, Edwards BA, Taranto Montemurro L, Azarbarzin A, Marques M, de Melo CM, Loring SH, Butler JP, White DP, Wellman A. Quantifying the Arousal Threshold Using Polysomnography in Obstructive Sleep Apnea. Sleep. 2018 01 01; 41(1). PMID: 29228393.
    Citations: 4     Fields:    
  10. de Melo CM, Taranto-Montemurro L, Butler JP, White DP, Loring SH, Azarbarzin A, Marques M, Berger PJ, Wellman A, Sands SA. Stable Breathing in Patients With Obstructive Sleep Apnea Is Associated With Increased Effort but Not Lowered Metabolic Rate. Sleep. 2017 10 01; 40(10). PMID: 28977669.
    Citations: 1     Fields:    Translation:Humans
  11. Azarbarzin A, Marques M, Sands SA, Op de Beeck S, Genta PR, Taranto-Montemurro L, de Melo CM, Messineo L, Vanderveken OM, White DP, Wellman A. Predicting epiglottic collapse in patients with obstructive sleep apnoea. Eur Respir J. 2017 09; 50(3). PMID: 28931660.
    Citations: 2     Fields:    Translation:Humans
  12. White DP. Advanced Concepts in the Pathophysiology of Obstructive Sleep Apnea. Adv Otorhinolaryngol. 2017; 80:7-16. PMID: 28738382.
    Citations: 1     Fields:    Translation:Humans
  13. Taranto-Montemurro L, Sands SA, Azarbarzin A, Marques M, de Melo CM, Edwards BA, Eckert DJ, Messineo L, White DP, Wellman A. Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults. Ann Am Thorac Soc. 2017 Jul; 14(7):1177-1183. PMID: 28387543.
    Citations: 2     Fields:    Translation:Humans
  14. Genta PR, Sands SA, Butler JP, Loring SH, Katz ES, Demko BG, Kezirian EJ, White DP, Wellman A. Airflow Shape Is Associated With the Pharyngeal Structure Causing OSA. Chest. 2017 09; 152(3):537-546. PMID: 28651794.
    Citations: 5     Fields:    Translation:Humans
  15. Taranto-Montemurro L, Sands SA, Edwards BA, Eckert DJ, White DP, Wellman A. Reply: Is the Muscle the Only Potential Target of Desipramine in Obstructive Sleep Apnea Syndrome? Am J Respir Crit Care Med. 2017 06 15; 195(12):1678-1679. PMID: 28186830.
    Citations:    Fields:    Translation:Humans
  16. Cori JM, Thornton T, O'Donoghue FJ, Rochford PD, White DP, Trinder J, Jordan AS. Arousal-Induced Hypocapnia Does Not Reduce Genioglossus Activity in Obstructive Sleep Apnea. Sleep. 2017 06 01; 40(6). PMID: 28419356.
    Citations: 1     Fields:    Translation:Humans
  17. Landry SA, Joosten SA, Eckert DJ, Jordan AS, Sands SA, White DP, Malhotra A, Wellman A, Hamilton GS, Edwards BA. Therapeutic CPAP Level Predicts Upper Airway Collapsibility in Patients With Obstructive Sleep Apnea. Sleep. 2017 06 01; 40(6). PMID: 28419320.
    Citations: 8     Fields:    Translation:Humans
  18. Landry SA, Joosten SA, Sands SA, White DP, Malhotra A, Wellman A, Hamilton GS, Edwards BA. Response to a combination of oxygen and a hypnotic as treatment for obstructive sleep apnoea is predicted by a patient's therapeutic CPAP requirement. Respirology. 2017 08; 22(6):1219-1224. PMID: 28409851.
    Citations: 1     Fields:    Translation:Humans
  19. de Raaff CAL, Gorter-Stam MAW, de Vries N, Sinha AC, Jaap Bonjer H, Chung F, Coblijn UK, Dahan A, van den Helder RS, Hilgevoord AAJ, Hillman DR, Margarson MP, Mattar SG, Mulier JP, Ravesloot MJL, Reiber BMM, van Rijswijk AS, Singh PM, Steenhuis R, Tenhagen M, Vanderveken OM, Verbraecken J, White DP, van der Wielen N, van Wagensveld BA. Perioperative management of obstructive sleep apnea in bariatric surgery: a consensus guideline. Surg Obes Relat Dis. 2017 Jul; 13(7):1095-1109. PMID: 28666588.
    Citations: 3     Fields:    Translation:Humans
  20. Marques M, Genta PR, Sands SA, Azarbazin A, de Melo C, Taranto-Montemurro L, White DP, Wellman A. Effect of Sleeping Position on Upper Airway Patency in Obstructive Sleep Apnea Is Determined by the Pharyngeal Structure Causing Collapse. Sleep. 2017 03 01; 40(3). PMID: 28329099.
    Citations: 2     Fields:    Translation:Humans
  21. Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A. Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients With Obstructive Sleep Apnea. Sleep. 2017 02 01; 40(2). PMID: 28364504.
    Citations: 1     Fields:    Translation:Humans
  22. Azarbarzin A, Sands SA, Taranto-Montemurro L, Oliveira Marques MD, Genta PR, Edwards BA, Butler J, White DP, Wellman A. Estimation of Pharyngeal Collapsibility During Sleep by Peak Inspiratory Airflow. Sleep. 2017 01 01; 40(1). PMID: 28364460.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  23. Liao P, Wong J, Singh M, Wong DT, Islam S, Andrawes M, Shapiro CM, White DP, Chung F. Postoperative Oxygen Therapy in Patients With OSA: A Randomized Controlled Trial. Chest. 2017 Mar; 151(3):597-611. PMID: 28007620.
    Citations: 2     Fields:    Translation:Humans
  24. Edwards BA, Andara C, Landry S, Sands SA, Joosten SA, Owens RL, White DP, Hamilton GS, Wellman A. Upper-Airway Collapsibility and Loop Gain Predict the Response to Oral Appliance Therapy in Patients with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2016 12 01; 194(11):1413-1422. PMID: 27181367.
    Citations: 16     Fields:    Translation:Humans
  25. Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A. Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients with Obstructive Sleep Apnea. Sleep. 2016 Nov 28. PMID: 27923429.
    Citations:    
  26. Edwards BA, Sands SA, Owens RL, Eckert DJ, Landry S, White DP, Malhotra A, Wellman A. The Combination of Supplemental Oxygen and a Hypnotic Markedly Improves Obstructive Sleep Apnea in Patients with a Mild to Moderate Upper Airway Collapsibility. Sleep. 2016 11 01; 39(11):1973-1983. PMID: 27634790.
    Citations: 8     Fields:    Translation:Humans
  27. Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A. Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation. Eur Respir J. 2016 11; 48(5):1340-1350. PMID: 27799387.
    Citations: 11     Fields:    Translation:HumansCells
  28. Taranto-Montemurro L, Edwards BA, Sands SA, Marques M, Eckert DJ, White DP, Wellman A. Desipramine Increases Genioglossus Activity and Reduces Upper Airway Collapsibility during Non-REM Sleep in Healthy Subjects. Am J Respir Crit Care Med. 2016 10 01; 194(7):878-885. PMID: 26967681.
    Citations: 15     Fields:    Translation:Humans
  29. Joffe H, Crawford SL, Freeman MP, White DP, Bianchi MT, Kim S, Economou N, Camuso J, Hall JE, Cohen LS. Independent Contributions of Nocturnal Hot Flashes and Sleep Disturbance to Depression in Estrogen-Deprived Women. J Clin Endocrinol Metab. 2016 10; 101(10):3847-3855. PMID: 27680875.
    Citations: 8     Fields:    Translation:Humans
  30. Azarbarzin A, Sands SA, Taranto-Montemurro L, Oliveira Marques MD, Genta PR, Edwards BA, Butler J, White DP, Wellman A. Estimation of pharyngeal collapsibility during sleep by peak inspiratory airflow. Sleep. 2016 Sep 09. PMID: 27634788.
    Citations:    
  31. McEvoy RD, Antic NA, Heeley E, Luo Y, Ou Q, Zhang X, Mediano O, Chen R, Drager LF, Liu Z, Chen G, Du B, McArdle N, Mukherjee S, Tripathi M, Billot L, Li Q, Lorenzi-Filho G, Barbe F, Redline S, Wang J, Arima H, Neal B, White DP, Grunstein RR, Zhong N, Anderson CS. CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea. N Engl J Med. 2016 09 08; 375(10):919-31. PMID: 27571048.
    Citations: 116     Fields:    Translation:Humans
  32. Bianchi MT, Kim S, Galvan T, White DP, Joffe H. Nocturnal Hot Flashes: Relationship to Objective Awakenings and Sleep Stage Transitions. J Clin Sleep Med. 2016 07 15; 12(7):1003-9. PMID: 26951410.
    Citations: 5     Fields:    Translation:Humans
  33. White DP. Pharmacologic Approaches to the Treatment of Obstructive Sleep Apnea. Sleep Med Clin. 2016 Jun; 11(2):203-12. PMID: 27236057.
    Citations: 1     Fields:    Translation:Humans
  34. Murase K, Ono K, Yoneda T, Iguchi M, Yokomatsu T, Mizoguchi T, Izumi T, Akao M, Miki S, Nohara R, Ueshima K, Mishima M, Kimura T, White DP, Chin K. Adaptive servoventilation versus oxygen therapy for sleep disordered breathing in patients with heart failure: a randomised trial. Open Heart. 2016; 3(1):e000366. PMID: 27099761.
    Citations:    
  35. Carberry JC, Jordan AS, White DP, Wellman A, Eckert DJ. Upper Airway Collapsibility (Pcrit) and Pharyngeal Dilator Muscle Activity are Sleep Stage Dependent. Sleep. 2016 Mar 01; 39(3):511-21. PMID: 26612386; PMCID: PMC4763361.
    Citations: 13     Fields:    Translation:Humans
  36. Genta PR, Edwards BA, Sands SA, Owens RL, Butler JP, Loring SH, White DP, Wellman A. Tube Law of the Pharyngeal Airway in Sleeping Patients with Obstructive Sleep Apnea. Sleep. 2016 Feb 01; 39(2):337-43. PMID: 26446124; PMCID: PMC4712389.
    Citations: 1     Fields:    Translation:Humans
  37. White DP. Is Continuous Positive Airway Pressure an Effective and Practical Antihypertensive Agent? Am J Respir Crit Care Med. 2016 Feb 01; 193(3):238-9. PMID: 26829422.
    Citations: 1     Fields:    Translation:Humans
  38. Lo YL, Ni YL, Wang TY, Lin TY, Li HY, White DP, Lin JR, Kuo HP. Bispectral Index in Evaluating Effects of Sedation Depth on Drug-Induced Sleep Endoscopy. J Clin Sleep Med. 2015 Sep 15; 11(9):1011-20. PMID: 25979098; PMCID: PMC4543245.
    Citations: 8     Fields:    Translation:Humans
  39. White DP, Criner GJ, Dreher M, Hart N, Peyerl FW, Wolfe LF, Chin SA. The role of noninvasive ventilation in the management and mitigation of exacerbations and hospital admissions/readmissions for the patient with moderate to severe COPD (multimedia activity). Chest. 2015 Jun; 147(6):1704-1705. PMID: 26033131.
    Citations:    Fields:    Translation:Humans
  40. Owens RL, Edwards BA, Eckert DJ, Jordan AS, Sands SA, Malhotra A, White DP, Loring SH, Butler JP, Wellman A. An Integrative Model of Physiological Traits Can be Used to Predict Obstructive Sleep Apnea and Response to Non Positive Airway Pressure Therapy. Sleep. 2015 Jun 01; 38(6):961-70. PMID: 25515107; PMCID: PMC4434563.
    Citations: 31     Fields:    Translation:Humans
  41. Edwards BA, Eckert DJ, McSharry DG, Sands SA, Desai A, Kehlmann G, Bakker JP, Genta PR, Owens RL, White DP, Wellman A, Malhotra A. Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2014 Dec 01; 190(11):1293-300. PMID: 25321848; PMCID: PMC4315811.
    Citations: 34     Fields:    Translation:Humans
  42. White DP. New therapies for obstructive sleep apnea. Semin Respir Crit Care Med. 2014 Oct; 35(5):621-8. PMID: 25353107.
    Citations: 3     Fields:    Translation:Humans
  43. Wellman A, Genta PR, Owens RL, Edwards BA, Sands SA, Loring SH, White DP, Jackson AC, Pedersen OF, Butler JP. Test of the Starling resistor model in the human upper airway during sleep. J Appl Physiol (1985). 2014 Dec 15; 117(12):1478-85. PMID: 25324514; PMCID: PMC4269684.
    Citations: 6     Fields:    Translation:Humans
  44. Terrill PI, Edwards BA, Nemati S, Butler JP, Owens RL, Eckert DJ, White DP, Malhotra A, Wellman A, Sands SA. Quantifying the ventilatory control contribution to sleep apnoea using polysomnography. Eur Respir J. 2015 Feb; 45(2):408-18. PMID: 25323235; PMCID: PMC4348093.
    Citations: 38     Fields:    Translation:Humans
  45. Sands SA, Eckert DJ, Jordan AS, Edwards BA, Owens RL, Butler JP, Schwab RJ, Loring SH, Malhotra A, White DP, Wellman A. Enhanced upper-airway muscle responsiveness is a distinct feature of overweight/obese individuals without sleep apnea. Am J Respir Crit Care Med. 2014 Oct 15; 190(8):930-7. PMID: 25191791; PMCID: PMC4299579.
    Citations: 26     Fields:    Translation:Humans
  46. Edwards BA, Sands SA, Owens RL, White DP, Genta PR, Butler JP, Malhotra A, Wellman A. Effects of hyperoxia and hypoxia on the physiological traits responsible for obstructive sleep apnoea. J Physiol. 2014 Oct 15; 592(20):4523-35. PMID: 25085887; PMCID: PMC4287742.
    Citations: 10     Fields:    Translation:Humans
  47. Genta PR, Owens RL, Edwards BA, Sands SA, Eckert DJ, Butler JP, Loring SH, Malhotra A, Jackson AC, White DP, Wellman A. Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway. Respir Physiol Neurobiol. 2014 Sep 15; 201:55-9. PMID: 25020212; PMCID: PMC4131868.
    Citations: 7     Fields:    Translation:Humans
  48. Edwards BA, Wellman A, Sands SA, Owens RL, Eckert DJ, White DP, Malhotra A. Obstructive sleep apnea in older adults is a distinctly different physiological phenotype. Sleep. 2014 Jul 01; 37(7):1227-36. PMID: 25061251; PMCID: PMC4098808.
    Citations: 20     Fields:    Translation:Humans
  49. Eckert DJ, Malhotra A, Wellman A, White DP. Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold. Sleep. 2014 Apr 01; 37(4):811-9. PMID: 24899767; PMCID: PMC4044741.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  50. Pavlova M, Abdennadher M, Singh K, Katz E, Llewellyn N, Zarowsky M, White DP, Dworetzky BA, Kothare SV. Advantages of respiratory monitoring during video-EEG evaluation to differentiate epileptic seizures from other events. Epilepsy Behav. 2014 Mar; 32:142-4. PMID: 24561659; PMCID: PMC4026047.
    Citations:    Fields:    Translation:Humans
  51. Eckert DJ, White DP, Jordan AS, Malhotra A, Wellman A. Reply: Arousal threshold in obstructive sleep apnea. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):373-4. PMID: 24484350.
    Citations: 2     Fields:    Translation:Humans
  52. Owens RL, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. The classical Starling resistor model often does not predict inspiratory airflow patterns in the human upper airway. J Appl Physiol (1985). 2014 Apr 15; 116(8):1105-12. PMID: 24458746; PMCID: PMC4035785.
    Citations: 8     Fields:    Translation:Humans
  53. Montesi SB, Bakker JP, Macdonald M, Hueser L, Pittman S, White DP, Malhotra A. Air leak during CPAP titration as a risk factor for central apnea. J Clin Sleep Med. 2013 Nov 15; 9(11):1187-91. PMID: 24235901; PMCID: PMC3805805.
    Citations: 13     Fields:    Translation:Humans
  54. White DP. Reply: Objective measurement of the therapeutic effectiveness of continuous positive airway pressure versus oral appliance therapy for the treatment of obstructive sleep apnea. Am J Respir Crit Care Med. 2013 Nov 01; 188(9):1163-4. PMID: 24180445; PMCID: PMC3863743.
    Citations:    Fields:    Translation:Humans
  55. Pavlova M, Singh K, Abdennadher M, Katz ES, Dworetzky BA, White DP, Llewellyn N, Kothare SV. Comparison of cardiorespiratory and EEG abnormalities with seizures in adults and children. Epilepsy Behav. 2013 Dec; 29(3):537-41. PMID: 24140516.
    Citations: 4     Fields:    Translation:Humans
  56. Eckert DJ, White DP, Jordan AS, Malhotra A, Wellman A. Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):996-1004. PMID: 23721582; PMCID: PMC3826282.
    Citations: 144     Fields:    Translation:Humans
  57. White DP, Shafazand S. Mandibular advancement device vs. CPAP in the treatment of obstructive sleep apnea: are they equally effective in Short term health outcomes? J Clin Sleep Med. 2013 Sep 15; 9(9):971-2. PMID: 23997711; PMCID: PMC3746726.
    Citations: 8     Fields:    Translation:Humans
  58. Joffe H, White DP, Crawford SL, McCurnin KE, Economou N, Connors S, Hall JE. Adverse effects of induced hot flashes on objectively recorded and subjectively reported sleep: results of a gonadotropin-releasing hormone agonist experimental protocol. Menopause. 2013 Sep; 20(9):905-14. PMID: 23481119; PMCID: PMC3687015.
    Citations: 9     Fields:    Translation:Humans
  59. Liu SX, Lee MC, Atakhorrami M, Tatousek J, McCormack M, Yung R, Hart N, White DP. Economic assessment of home-based COPD management programs. COPD. 2013 Dec; 10(6):640-9. PMID: 23848542.
    Citations: 3     Fields:    Translation:Humans
  60. White DP. Continuous positive airway pressure versus the mandibular advancing splint: are they equally effective in obstructive sleep apnea management? Am J Respir Crit Care Med. 2013 Apr 15; 187(8):795-7. PMID: 23586381.
    Citations: 1     Fields:    Translation:Humans
  61. Edwards BA, Connolly JG, Campana LM, Sands SA, Trinder JA, White DP, Wellman A, Malhotra A. Acetazolamide attenuates the ventilatory response to arousal in patients with obstructive sleep apnea. Sleep. 2013 Feb 01; 36(2):281-5. PMID: 23372276; PMCID: PMC3543060.
    Citations: 23     Fields:    Translation:Humans
  62. Veasey S, White DP. Obstructive sleep apnea pharmacotherapy: one step closer. Am J Respir Crit Care Med. 2013 Feb 01; 187(3):226-7. PMID: 23378437.
    Citations: 3     Fields:    Translation:Animals
  63. Wellman A, Edwards BA, Sands SA, Owens RL, Nemati S, Butler J, Passaglia CL, Jackson AC, Malhotra A, White DP. A simplified method for determining phenotypic traits in patients with obstructive sleep apnea. J Appl Physiol (1985). 2013 Apr; 114(7):911-22. PMID: 23349453.
    Citations: 48     Fields:    Translation:Humans
  64. Kushida CA, Nichols DA, Holmes TH, Quan SF, Walsh JK, Gottlieb DJ, Simon RD, Guilleminault C, White DP, Goodwin JL, Schweitzer PK, Leary EB, Hyde PR, Hirshkowitz M, Green S, McEvoy LK, Chan C, Gevins A, Kay GG, Bloch DA, Crabtree T, Dement WC. Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep. 2012 Dec 01; 35(12):1593-602. PMID: 23204602.
    Citations: 58     Fields:    Translation:Humans
  65. White DP, Younes MK. Obstructive sleep apnea. Compr Physiol. 2012 Oct; 2(4):2541-94. PMID: 23720258.
    Citations: 25     Fields:    Translation:Humans
  66. Owens RL, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. Upper airway collapsibility and patterns of flow limitation at constant end-expiratory lung volume. J Appl Physiol (1985). 2012 Sep 01; 113(5):691-9. PMID: 22628372; PMCID: PMC3472473.
    Citations: 13     Fields:    Translation:Humans
  67. Nicholas CL, Jordan AS, Heckel L, Worsnop C, Bei B, Saboisky JP, Eckert DJ, White DP, Malhotra A, Trinder J. Discharge patterns of human tensor palatini motor units during sleep onset. Sleep. 2012 May 01; 35(5):699-707. PMID: 22547896; PMCID: PMC3321429.
    Citations: 6     Fields:    Translation:HumansCells
  68. Kairaitis K, Verma M, Amatoury J, Wheatley JR, White DP, Amis TC. A threshold lung volume for optimal mechanical effects on upper airway airflow dynamics: studies in an anesthetized rabbit model. J Appl Physiol (1985). 2012 Apr; 112(7):1197-205. PMID: 22241061.
    Citations: 5     Fields:    Translation:Animals
  69. Edwards BA, Sands SA, Eckert DJ, White DP, Butler JP, Owens RL, Malhotra A, Wellman A. Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea. J Physiol. 2012 Mar 01; 590(5):1199-211. PMID: 22219335; PMCID: PMC3381825.
    Citations: 60     Fields:    Translation:HumansCTClinical Trials
  70. Rajaratnam SM, Barger LK, Lockley SW, Shea SA, Wang W, Landrigan CP, O'Brien CS, Qadri S, Sullivan JP, Cade BE, Epstein LJ, White DP, Czeisler CA. Sleep disorders, health, and safety in police officers. JAMA. 2011 Dec 21; 306(23):2567-78. PMID: 22187276.
    Citations: 47     Fields:    Translation:Humans
  71. Saboisky JP, Stashuk DW, Hamilton-Wright A, Carusona AL, Campana LM, Trinder J, Eckert DJ, Jordan AS, McSharry DG, White DP, Nandedkar S, David WS, Malhotra A. Neurogenic changes in the upper airway of patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2012 Feb 01; 185(3):322-9. PMID: 22016445; PMCID: PMC3297112.
    Citations: 21     Fields:    Translation:HumansCells
  72. Babaeizadeh S, Zhou SH, Pittman SD, White DP. Electrocardiogram-derived respiration in screening of sleep-disordered breathing. J Electrocardiol. 2011 Nov-Dec; 44(6):700-6. PMID: 21908002.
    Citations: 5     Fields:    Translation:Humans
  73. Edwards BA, White DP. Control of the pharyngeal musculature during wakefulness and sleep: implications in normal controls and sleep apnea. Head Neck. 2011 Oct; 33 Suppl 1:S37-45. PMID: 21901775; PMCID: PMC3179569.
    Citations: 4     Fields:    Translation:Humans
  74. Eckert DJ, Lo YL, Saboisky JP, Jordan AS, White DP, Malhotra A. Sensorimotor function of the upper-airway muscles and respiratory sensory processing in untreated obstructive sleep apnea. J Appl Physiol (1985). 2011 Dec; 111(6):1644-53. PMID: 21885797; PMCID: PMC3233889.
    Citations: 21     Fields:    Translation:Humans
  75. Jordan AS, Eckert DJ, Wellman A, Trinder JA, Malhotra A, White DP. Termination of respiratory events with and without cortical arousal in obstructive sleep apnea. Am J Respir Crit Care Med. 2011 Nov 15; 184(10):1183-91. PMID: 21836132; PMCID: PMC3262022.
    Citations: 28     Fields:    Translation:Humans
  76. Hedner J, White DP, Malhotra A, Herscovici S, Pittman SD, Zou D, Grote L, Pillar G. Sleep staging based on autonomic signals: a multi-center validation study. J Clin Sleep Med. 2011 Jun 15; 7(3):301-6. PMID: 21677901; PMCID: PMC3113970.
    Citations: 13     Fields:    Translation:Humans
  77. Eckert DJ, Owens RL, Kehlmann GB, Wellman A, Rahangdale S, Yim-Yeh S, White DP, Malhotra A. Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold. Clin Sci (Lond). 2011 Jun; 120(12):505-14. PMID: 21269278; PMCID: PMC3415379.
    Citations: 64     Fields:    Translation:HumansCTClinical Trials
  78. Joffe H, Petrillo LF, Koukopoulos A, Viguera AC, Hirschberg A, Nonacs R, Somley B, Pasciullo E, White DP, Hall JE, Cohen LS. Increased estradiol and improved sleep, but not hot flashes, predict enhanced mood during the menopausal transition. J Clin Endocrinol Metab. 2011 Jul; 96(7):E1044-54. PMID: 21525161; PMCID: PMC3135198.
    Citations: 22     Fields:    Translation:Humans
  79. Wellman A, Eckert DJ, Jordan AS, Edwards BA, Passaglia CL, Jackson AC, Gautam S, Owens RL, Malhotra A, White DP. A method for measuring and modeling the physiological traits causing obstructive sleep apnea. J Appl Physiol (1985). 2011 Jun; 110(6):1627-37. PMID: 21436459; PMCID: PMC3119134.
    Citations: 59     Fields:    Translation:Humans
  80. Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7. PMID: 21051598.
    Citations: 466     Fields:    Translation:HumansCells
  81. Nicholas CL, Bei B, Worsnop C, Malhotra A, Jordan AS, Saboisky JP, Chan JK, Duckworth E, White DP, Trinder J. Motor unit recruitment in human genioglossus muscle in response to hypercapnia. Sleep. 2010 Nov; 33(11):1529-38. PMID: 21102995; PMCID: PMC2954703.
    Citations: 15     Fields:    Translation:HumansCells
  82. Saboisky JP, Jordan AS, Eckert DJ, White DP, Trinder JA, Nicholas CL, Gautam S, Malhotra A. Recruitment and rate-coding strategies of the human genioglossus muscle. J Appl Physiol (1985). 2010 Dec; 109(6):1939-49. PMID: 20947713; PMCID: PMC3006403.
    Citations: 24     Fields:    Translation:HumansCells
  83. Babaeizadeh S, White DP, Pittman SD, Zhou SH. Automatic detection and quantification of sleep apnea using heart rate variability. J Electrocardiol. 2010 Nov-Dec; 43(6):535-41. PMID: 20719334.
    Citations: 3     Fields:    Translation:Humans
  84. Krystal AD, Zammit GK, Wyatt JK, Quan SF, Edinger JD, White DP, Chiacchierini RP, Malhotra A. The effect of vestibular stimulation in a four-hour sleep phase advance model of transient insomnia. J Clin Sleep Med. 2010 Aug 15; 6(4):315-21. PMID: 20726278; PMCID: PMC2919660.
    Citations: 4     Fields:    Translation:Humans
  85. Kezirian EJ, Malhotra A, Goldberg AN, White DP. Changes in obstructive sleep apnea severity, biomarkers, and quality of life after multilevel surgery. Laryngoscope. 2010 Jul; 120(7):1481-8. PMID: 20564750.
    Citations: 7     Fields:    Translation:Humans
  86. Jordan AS, White DP, Owens RL, Eckert DJ, Rahangdale S, Yim-Yeh S, Malhotra A. The effect of increased genioglossus activity and end-expiratory lung volume on pharyngeal collapse. J Appl Physiol (1985). 2010 Aug; 109(2):469-75. PMID: 20507968; PMCID: PMC2928593.
    Citations: 22     Fields:    Translation:Humans
  87. Patz DS, Swihart B, White DP. CPAP pressure requirements for obstructive sleep apnea patients at varying altitudes. Sleep. 2010 May; 33(5):715-8. PMID: 20469814; PMCID: PMC2864887.
    Citations: 3     Fields:    Translation:Humans
  88. Eckert DJ, Saboisky JP, Jordan AS, White DP, Malhotra A. A secondary reflex suppression phase is present in genioglossus but not tensor palatini in response to negative upper airway pressure. J Appl Physiol (1985). 2010 Jun; 108(6):1619-24. PMID: 20378702; PMCID: PMC2886693.
    Citations: 6     Fields:    Translation:Humans
  89. Kezirian EJ, White DP, Malhotra A, Ma W, McCulloch CE, Goldberg AN. Interrater reliability of drug-induced sleep endoscopy. Arch Otolaryngol Head Neck Surg. 2010 Apr; 136(4):393-7. PMID: 20403857.
    Citations: 46     Fields:    Translation:HumansCTClinical Trials
  90. Wilkinson V, Malhotra A, Nicholas CL, Worsnop C, Jordan AS, Butler JE, Saboisky JP, Gandevia SC, White DP, Trinder J. Discharge patterns of human genioglossus motor units during arousal from sleep. Sleep. 2010 Mar; 33(3):379-87. PMID: 20337197; PMCID: PMC2831433.
    Citations: 19     Fields:    Translation:HumansCells
  91. Amir O, Barak-Shinar D, Amos Y, MacDonald M, Pittman S, White DP. An automated sleep-analysis system operated through a standard hospital monitor. J Clin Sleep Med. 2010 Feb 15; 6(1):59-63. PMID: 20191939; PMCID: PMC2823277.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  92. White DP. Auto-PEEP to treat obstructive sleep apnea. J Clin Sleep Med. 2009 Dec 15; 5(6):538-9. PMID: 20465020; PMCID: PMC2792969.
    Citations: 1     Fields:    Translation:Humans
  93. Owens RL, Malhotra A, Eckert DJ, White DP, Jordan AS. The influence of end-expiratory lung volume on measurements of pharyngeal collapsibility. J Appl Physiol (1985). 2010 Feb; 108(2):445-51. PMID: 19940097; PMCID: PMC3774250.
    Citations: 36     Fields:    Translation:Humans
  94. White DP. The Future of Sleep and Circadian Testing. Sleep Med Clin. 2009 Sep 01; 4(3):455-463. PMID: 20161140.
    Citations:    Fields:    
  95. White DP. Opioid-induced suppression of genioglossal muscle activity: is it clinically important? J Physiol. 2009 Jul 15; 587(Pt 14):3421-2. PMID: 19602634; PMCID: PMC2742267.
    Citations: 2     Fields:    Translation:AnimalsCells
  96. Joffe H, Soares CN, Thurston RC, White DP, Cohen LS, Hall JE. Depression is associated with worse objectively and subjectively measured sleep, but not more frequent awakenings, in women with vasomotor symptoms. Menopause. 2009 Jul-Aug; 16(4):671-9. PMID: 19197217; PMCID: PMC3405549.
    Citations: 17     Fields:    Translation:Humans
  97. Jordan AS, White DP, Lo YL, Wellman A, Eckert DJ, Yim-Yeh S, Eikermann M, Smith SA, Stevenson KE, Malhotra A. Airway dilator muscle activity and lung volume during stable breathing in obstructive sleep apnea. Sleep. 2009 Mar; 32(3):361-8. PMID: 19294956; PMCID: PMC2647790.
    Citations: 45     Fields:    Translation:Humans
  98. Eckert DJ, Malhotra A, Lo YL, White DP, Jordan AS. The influence of obstructive sleep apnea and gender on genioglossus activity during rapid eye movement sleep. Chest. 2009 Apr; 135(4):957-964. PMID: 19118266; PMCID: PMC3877689.
    Citations: 33     Fields:    Translation:Humans
  99. McGuire M, Tartar JL, Cao Y, McCarley RW, White DP, Strecker RE, Ling L. Sleep fragmentation impairs ventilatory long-term facilitation via adenosine A1 receptors. J Physiol. 2008 Nov 01; 586(21):5215-29. PMID: 18787037; PMCID: PMC2652159.
    Citations: 4     Fields:    Translation:Animals
  100. Somers VK, White DP, Amin R, Abraham WT, Costa F, Culebras A, Daniels S, Floras JS, Hunt CE, Olson LJ, Pickering TG, Russell R, Woo M, Young T. Sleep apnea and cardiovascular disease: an American Heart Association/american College Of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council On Cardiovascular Nursing. In collaboration with the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health). Circulation. 2008 Sep 02; 118(10):1080-111. PMID: 18725495.
    Citations: 319     Fields:    Translation:Humans
  101. Somers VK, White DP, Amin R, Abraham WT, Costa F, Culebras A, Daniels S, Floras JS, Hunt CE, Olson LJ, Pickering TG, Russell R, Woo M, Young T. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. J Am Coll Cardiol. 2008 Aug 19; 52(8):686-717. PMID: 18702977.
    Citations: 201     Fields:    Translation:Humans
  102. Wellman A, Malhotra A, Jordan AS, Stevenson KE, Gautam S, White DP. Effect of oxygen in obstructive sleep apnea: role of loop gain. Respir Physiol Neurobiol. 2008 Jul 31; 162(2):144-51. PMID: 18577470; PMCID: PMC4332598.
    Citations: 60     Fields:    Translation:Humans
  103. Eikermann M, Malhotra A, Fassbender P, Zaremba S, Jordan AS, Gautam S, White DP, Chamberlin NL. Differential effects of isoflurane and propofol on upper airway dilator muscle activity and breathing. Anesthesiology. 2008 May; 108(5):897-906. PMID: 18431126; PMCID: PMC4939071.
    Citations: 11     Fields:    Translation:Animals
  104. Wilkinson V, Malhotra A, Nicholas CL, Worsnop C, Jordan AS, Butler JE, Saboisky JP, Gandevia SC, White DP, Trinder J. Discharge patterns of human genioglossus motor units during sleep onset. Sleep. 2008 Apr; 31(4):525-33. PMID: 18457240; PMCID: PMC2279758.
    Citations: 31     Fields:    Translation:HumansCells
  105. Heinzer R, White DP, Malhotra A, Lo YL, Dover L, Stevenson KE, Jordan AS. Effect of expiratory positive airway pressure on sleep disordered breathing. Sleep. 2008 Mar; 31(3):429-32. PMID: 18363320; PMCID: PMC2276743.
    Citations: 9     Fields:    Translation:Humans
  106. MacDonald M, Fang J, Pittman SD, White DP, Malhotra A. The current prevalence of sleep disordered breathing in congestive heart failure patients treated with beta-blockers. J Clin Sleep Med. 2008 Feb 15; 4(1):38-42. PMID: 18350960; PMCID: PMC2276820.
    Citations: 43     Fields:    Translation:Humans
  107. White DP. Monitoring peripheral arterial tone (PAT) to diagnose sleep apnea in the home. J Clin Sleep Med. 2008 Feb 15; 4(1):73. PMID: 18350969; PMCID: PMC2276832.
    Citations: 3     Fields:    Translation:Humans
  108. Heinzer RC, White DP, Jordan AS, Lo YL, Dover L, Stevenson K, Malhotra A. Trazodone increases arousal threshold in obstructive sleep apnoea. Eur Respir J. 2008 Jun; 31(6):1308-12. PMID: 18256066; PMCID: PMC2732198.
    Citations: 33     Fields:    Translation:Humans
  109. Saboisky JP, Butler JE, McKenzie DK, Gorman RB, Trinder JA, White DP, Gandevia SC. Neural drive to human genioglossus in obstructive sleep apnoea. J Physiol. 2007 Nov 15; 585(