Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Tatsuo Kawai, Ph.D., M.D.

Title
Institution
Department
Address
Phone
Fax

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI163806 (KAWAI, TATSUO) May 20, 2021 - Apr 30, 2023
    NIH
    Mcl-1 inhibition for induction of hematopoietic chimerism without nonselective myeloablative treatments in nonhuman primates
    Role: Principal Investigator
  2. R56AI139679 (KAWAI, TATSUO) Aug 6, 2018 - Jul 31, 2020
    NIH
    Inhibition of Bcl-2 for Induction of Mixed Chimerism and Renal Allograft Tolerance Without Myelosuppression
    Role: Principal Investigator
  3. R21AI126289 (KAWAI, TATSUO) Jun 1, 2016 - May 31, 2018
    NIH
    Inhibition of BCL-2 for induction of mixed chimerism without myelosuppressive conditioning
    Role: Principal Investigator
  4. U19AI102405 (COSIMI, A BENEDICT) Aug 1, 2012 - Dec 31, 2017
    NIH
    Approaches to Tolerance of Allogeneic Kidney and Islet Transplants
    Role: Co-Principal Investigator
  5. R01HL093131 (MADSEN, JOREN C) Sep 1, 2009 - May 31, 2012
    NIH
    Optimizing Mixed-Chimerism for Heart Transplantation in Non-Human Primates
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ma D, Hirose T, Lassiter G, Sasaki H, Rosales I, Coe TM, Rickert CG, Matheson R, Colvin RB, Qin W, Kan Y, Layer JV, Paragas VB, Stiede K, Hall KC, Youd ME, Queiroz LM, Westlin WF, Curtis M, Yang L, Markmann JF, Kawai T. Kidney transplantation from triple-knockout pigs expressing multiple human proteins in cynomolgus macaques. Am J Transplant. 2021 Jul 31. PMID: 34331749.
    Citations:    Fields:    
  2. Sommer W, O JM, Pruner KB, Dehnadi A, Ha Huh K, Robinson KA, Hanekamp I, Rosales I, Bean AS, Paster J, Oura T, Neal Smith R, Colvin R, Benichou G, Kawai T, Madsen JC, Allan JS. A Mixed-chimerism Protocol Utilizing Thymoglobulin and Belatacept Did Not Induce Lung Allograft Tolerance, Despite Previous Success in Renal Allotransplantation. Transplant Direct. 2021 Jun; 7(6):e705. PMID: 34056080.
    Citations:    
  3. Safa K, Elias N, Gilligan HM, Kawai T, Kotton CN. Successful Living Kidney Donation After COVID-19 Infection. Transplantation. 2021 01 01; 105(1):e4-e5. PMID: 33350629.
    Citations: 1     Fields:    Translation:Humans
  4. Murata T, Wada H, Otsuka R, Sasaki A, Tsuji H, Itoh M, Eguchi N, Kawai T, Seino KI. Establishment of an experimental model for MHC homo-to-hetero transplantation. Sci Rep. 2020 08 11; 10(1):13560. PMID: 32782297.
    Citations:    Fields:    Translation:HumansAnimals
  5. Michelakos T, Kontos F, Sekigami Y, Qadan M, Cai L, Catalano O, Deshpande V, Patel MS, Yamada T, Elias N, Dageforde LA, Kimura S, Kawai T, Tanabe KK, Markmann JF, Yeh H, Ferrone CR. Hepatectomy for Solitary Hepatocellular Carcinoma: Resection Margin Width Does Not Predict Survival. J Gastrointest Surg. 2021 07; 25(7):1727-1735. PMID: 32779082.
    Citations: 1     Fields:    Translation:Humans
  6. Issa F, Strober S, Leventhal JR, Kawai T, Kaufman DB, Levitsky J, Sykes M, Mas V, Wood KJ, Bridges N, Welniak LA, Chandran S, Madsen JC, Nickerson P, Demetris AJ, Lakkis FG, Thomson AW. The Fourth International Workshop on Clinical Transplant Tolerance. Am J Transplant. 2021 01; 21(1):21-31. PMID: 32529725.
    Citations: 1     Fields:    Translation:Humans
  7. Lee KW, Park JB, Park H, Kwon Y, Lee JS, Kim KS, Chung YJ, Rhu JS, Choi S, Kwon GY, Kim HJ, Kang ES, Jung CW, Shin EC, Kawai T, Kim SJ, Joh JW. Inducing Transient Mixed Chimerism for Allograft Survival Without Maintenance Immunosuppression With Combined Kidney and Bone Marrow Transplantation: Protocol Optimization. Transplantation. 2020 07; 104(7):1472-1482. PMID: 31634324.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  8. Bethea E, Arvind A, Gustafson J, Andersson K, Pratt D, Bhan I, Thiim M, Corey K, Bloom P, Markmann J, Yeh H, Elias N, Kimura S, Dageforde LA, Cuenca A, Kawai T, Safa K, Williams W, Gilligan H, Sise M, Fishman J, Kotton C, Kim A, Rogers CC, Shao S, Cote M, Irwin L, Myoung P, Chung RT. Immediate administration of antiviral therapy after transplantation of hepatitis C-infected livers into uninfected recipients: Implications for therapeutic planning. Am J Transplant. 2020 06; 20(6):1619-1628. PMID: 31887236.
    Citations: 4     Fields:    Translation:HumansCells
  9. Matsunami M, Rosales IA, Adam BA, Oura T, Mengel M, Smith RN, Lee H, Cosimi AB, Colvin RB, Kawai T. Long-term Kinetics of Intragraft Gene Signatures in Renal Allograft Tolerance Induced by Transient Mixed Chimerism. Transplantation. 2019 11; 103(11):e334-e344. PMID: 31397805.
    Citations: 3     Fields:    Translation:AnimalsCells
  10. Spitzer TR, Tolkoff-Rubin N, Cosimi AB, McAfee S, Dey BR, Chen YB, Delmonico F, Sykes M, Sachs DH, Kawai T. Twenty-year Follow-up of Histocompatibility Leukocyte Antigen-matched Kidney and Bone Marrow Cotransplantation for Multiple Myeloma With End-stage Renal Disease: Lessons Learned. Transplantation. 2019 11; 103(11):2366-2372. PMID: 30801529.
    Citations: 4     Fields:    Translation:Humans
  11. Chen YB, Elias N, Heher E, McCune JS, Collier K, Li S, Del Rio C, El-Jawahri A, Williams W, Tolkoff-Rubin N, Fishman JA, McAfee S, Dey BR, DeFilipp Z, O'Donnell PV, Cosimi AB, Sachs D, Kawai T, Spitzer TR. Haploidentical hematopoietic cell and kidney transplantation for hematological malignancies and end-stage renal failure. Blood. 2019 07 11; 134(2):211-215. PMID: 31151984.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  12. Thaiss CC, Oura T, Sasaki H, Dehnadi A, Matsunami M, Rosales IA, Cosimi AB, Kawai T. Importance of Hematopoietic Mixed Chimerism for Induction of Renal Allograft Tolerance in Nonhuman Primates. Transplantation. 2019 04; 103(4):689-697. PMID: 30300283.
    Citations: 1     Fields:    Translation:Animals
  13. Panda N, Brackett D, Eymard C, Kawai T, Markmann J, Kotton CN, Andersson K, Yeh H. Liver Transplantation for Recurrent Cholangitis From Von Meyenburg Complexes. Transplant Direct. 2019 Mar; 5(3):e428. PMID: 30882033.
    Citations:    
  14. Oura T, Hotta K, Rosales I, Dehnadi A, Kawai K, Lee H, Benedict Cosimi A, Kawai T. Addition of Anti-CD40 Monoclonal Antibody to Nonmyeloablative Conditioning With Belatacept Abrogated Allograft Tolerance Despite Induction of Mixed Chimerism. Transplantation. 2019 01; 103(1):168-176. PMID: 30113996.
    Citations: 4     Fields:    Translation:Animals
  15. Kawai T, Leventhal J, Wood K, Strober S. Summary of the Third International Workshop on Clinical Tolerance. Am J Transplant. 2019 02; 19(2):324-330. PMID: 30133954.
    Citations: 9     Fields:    Translation:Humans
  16. Martins PN, Brüggenwirth IMA, McDaid J, Hertl M, Kawai T, Elias N, Chung RT, Markmann JF. Heat Stroke as a Cause of Liver Failure and Evaluation of Liver Transplant. Exp Clin Transplant. 2018 Aug 17. PMID: 30119616.
    Citations: 2     Fields:    
  17. Hotta K, Oura T, Dehnadi A, Boskovic S, Matsunami M, Rosales I, Smith RN, Colvin RB, Cosimi AB, Kawai T. Long-term Nonhuman Primate Renal Allograft Survival Without Ongoing Immunosuppression in Recipients of Delayed Donor Bone Marrow Transplantation. Transplantation. 2018 04; 102(4):e128-e136. PMID: 29300231.
    Citations: 8     Fields:    Translation:AnimalsCells
  18. Sasaki H, Oura T, Spitzer TR, Chen YB, Madsen JC, Allan J, Sachs DH, Cosimi AB, Kawai T. Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach. Hum Immunol. 2018 May; 79(5):258-265. PMID: 29175110.
    Citations: 11     Fields:    Translation:HumansAnimals
  19. Gao B, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer F, Saidman SL, Fu Y, Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E. Dynamics of B Cell Recovery In Kidney/Bone Marrow Transplant Recipients. Transplantation. 2017 11; 101(11):2722-2730. PMID: 28422925.
    Citations: 1     Fields:    Translation:HumansCells
  20. Oura T, Cosimi AB, Kawai T. Chimerism-based tolerance in organ transplantation: preclinical and clinical studies. Clin Exp Immunol. 2017 08; 189(2):190-196. PMID: 28369830.
    Citations: 11     Fields:    Translation:HumansAnimals
  21. Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M. Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance. Am J Transplant. 2017 Aug; 17(8):2020-2032. PMID: 28251801.
    Citations: 19     Fields:    Translation:HumansCells
  22. Cui J, Xu D, Ma J, Liu B, Kawai T, Yeh H, Schainfeld R, Irani Z. Stenoses in the surgically manipulated segment have better angioplasty response compared to the surgically naive segment in fistulas. J Vasc Access. 2017 May 15; 18(3):192-199. PMID: 28218364.
    Citations: 1     Fields:    Translation:Humans
  23. Duran-Struuck R, Sondermeijer HP, Bühler L, Alonso-Guallart P, Zitsman J, Kato Y, Wu A, McMurchy AN, Woodland D, Griesemer A, Martinez M, Boskovic S, Kawai T, Cosimi AB, Yang YG, Hu Z, Wuu CS, Slate A, Mapara M, Baker S, Tokarz R, D'Agati V, Hammer S, Pereira M, Lipkin WI, Wekerle T, Levings M, Sykes M. Effect of Ex Vivo-Expanded Recipient Regulatory T Cells on Hematopoietic Chimerism and Kidney Allograft Tolerance Across MHC Barriers in Cynomolgus Macaques. Transplantation. 2017 02; 101(2):274-283. PMID: 27846155.
    Citations: 29     Fields:    Translation:AnimalsCells
  24. Tsoulfas G, Agorastou P, Ko DS, Hertl M, Elias N, Cosimi AB, Kawai T. Laparoscopic vs open donor nephrectomy: Lessons learnt from single academic center experience. World J Nephrol. 2017 Jan 06; 6(1):45-52. PMID: 28101451.
    Citations: 5     
  25. Hotta K, Aoyama A, Oura T, Yamada Y, Tonsho M, Huh KH, Kawai K, Schoenfeld D, Allan JS, Madsen JC, Benichou G, Smith RN, Colvin RB, Sachs DH, Cosimi AB, Kawai T. Induced regulatory T cells in allograft tolerance via transient mixed chimerism. JCI Insight. 2016 Jul 07; 1(10). PMID: 27446989.
    Citations: 18     Fields:    
  26. Madariaga ML, Spencer PJ, Shanmugarajah K, Crisalli KA, Chang DC, Markmann JF, Elias N, Cosimi AB, Sachs DH, Kawai T. Effect of tolerance versus chronic immunosuppression protocols on the quality of life of kidney transplant recipients. JCI Insight. 2016 Jun 02; 1(8). PMID: 27336062.
    Citations: 9     Fields:    
  27. Chen YB, Kawai T, Spitzer TR. Combined Bone Marrow and Kidney Transplantation for the Induction of Specific Tolerance. Adv Hematol. 2016; 2016:6471901. PMID: 27239198.
    Citations: 11     
  28. Cui J, Steele D, Wenger J, Kawai T, Liu F, Elias N, Watkins MT, Irani Z. Hemodialysis arteriovenous fistula as first option not necessary in elderly patients. J Vasc Surg. 2016 May; 63(5):1326-32. PMID: 26776449.
    Citations: 10     Fields:    Translation:Humans
  29. Oura T, Ko DS, Boskovic S, O'Neil JJ, Chipashvili V, Koulmanda M, Hotta K, Kawai K, Nadazdin O, Smith RN, Cosimi AB, Kawai T. Kidney Versus Islet Allograft Survival After Induction of Mixed Chimerism With Combined Donor Bone Marrow Transplantation. Cell Transplant. 2016; 25(7):1331-41. PMID: 26337731.
    Citations: 10     Fields:    Translation:Animals
  30. Elias N, Cosimi AB, Kawai T. Clinical trials for induction of renal allograft tolerance. Curr Opin Organ Transplant. 2015 Aug; 20(4):406-11. PMID: 26147679.
    Citations: 9     Fields:    Translation:HumansAnimals
  31. Yamada Y, Nadazdin O, Boskovic S, Lee S, Zorn E, Smith RN, Colvin RB, Madsen JC, Cosimi AB, Kawai T, Benichou G. Repeated Injections of IL-2 Break Renal Allograft Tolerance Induced via Mixed Hematopoietic Chimerism in Monkeys. Am J Transplant. 2015 Dec; 15(12):3055-66. PMID: 26190648.
    Citations: 22     Fields:    Translation:Animals
  32. Lei J, Kim JI, Shi S, Zhang X, Machaidze Z, Lee S, Schuetz C, Martins PN, Oura T, Farkash EA, Rosales IA, Smith RN, Stott R, Lee KM, Soohoo J, Boskovic S, Cappetta K, Nadazdin OM, Yamada Y, Yeh H, Kawai T, Sachs DH, Benichou G, Markmann JF. Pilot Study Evaluating Regulatory T Cell-Promoting Immunosuppression and Nonimmunogenic Donor Antigen Delivery in a Nonhuman Primate Islet Allotransplantation Model. Am J Transplant. 2015 Oct; 15(10):2739-49. PMID: 26014796.
    Citations: 14     Fields:    Translation:AnimalsCells
  33. Tonsho M, Lee S, Aoyama A, Boskovic S, Nadazdin O, Capetta K, Smith RN, Colvin RB, Sachs DH, Cosimi AB, Kawai T, Madsen JC, Benichou G, Allan JS. Tolerance of Lung Allografts Achieved in Nonhuman Primates via Mixed Hematopoietic Chimerism. Am J Transplant. 2015 Aug; 15(8):2231-9. PMID: 25904524.
    Citations: 18     Fields:    Translation:Animals
  34. Oura T, Hotta K, Cosimi AB, Kawai T. Transient mixed chimerism for allograft tolerance. Chimerism. 2015 Apr 03; 6(1-2):21-6. PMID: 26517761.
    Citations: 4     Fields:    Translation:HumansAnimals
  35. Cui J, Kawai T, Irani Z. Catheter-directed Thrombolysis in Acute Superior Vena Cava Syndrome Caused by Central Venous Catheters. Semin Dial. 2015 Sep-Oct; 28(5):548-51. PMID: 25827021.
    Citations: 4     Fields:    Translation:Humans
  36. Aoyama A, Tonsho M, Ng CY, Lee S, Millington T, Nadazdin O, Wain JC, Cosimi AB, Sachs DH, Smith RN, Colvin RB, Kawai T, Madsen JC, Benichou G, Allan JS. Long-term lung transplantation in nonhuman primates. Am J Transplant. 2015 May; 15(5):1415-20. PMID: 25772308.
    Citations: 10     Fields:    Translation:AnimalsCells
  37. Granados JM, Benichou G, Kawai T. Hematopoietic stem cell infusion/transplantation for induction of allograft tolerance. Curr Opin Organ Transplant. 2015 Feb; 20(1):49-56. PMID: 25563992.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  38. Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J, Shen Y, Sykes M. Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Sci Transl Med. 2015 Jan 28; 7(272):272ra10. PMID: 25632034.
    Citations: 87     Fields:    Translation:HumansCells
  39. Ferdman J, Porcheray F, Gao B, Moore C, DeVito J, Dougherty S, Thomas MV, Farkash EA, Elias N, Kawai T, Malek SK, Tullius SG, Wong W, Zorn E. Expansion and somatic hypermutation of B-cell clones in rejected human kidney grafts. Transplantation. 2014 Oct 15; 98(7):766-72. PMID: 24825521.
    Citations: 9     Fields:    Translation:HumansCells
  40. Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ. Tolerance: one transplant for life. Transplantation. 2014 Jul 27; 98(2):117-21. PMID: 24926829.
    Citations: 16     Fields:    Translation:Humans
  41. Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman SL, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Smith RN, Colvin RB, Sykes M, Cosimi AB. Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant. 2014 Jul; 14(7):1599-611. PMID: 24903438.
    Citations: 93     Fields:    Translation:Humans
  42. Kawai T, Ohishi M, Onishi M, Ito N, Takeya Y, Oguro R, Takami Y, Yamamoto K, Rakugi H. Prognostic impact of regional arterial stiffness in hypertensive patients. Heart Vessels. 2015 May; 30(3):338-46. PMID: 24566589.
    Citations: 11     Fields:    Translation:Humans
  43. Sachs DH, Kawai T, Sykes M. Induction of tolerance through mixed chimerism. Cold Spring Harb Perspect Med. 2014 Jan 01; 4(1):a015529. PMID: 24384815.
    Citations: 45     Fields:    Translation:HumansAnimals
  44. Lee S, Yamada Y, Tonsho M, Boskovic S, Nadazdin O, Schoenfeld D, Cappetta K, Atif M, Smith RN, Cosimi AB, Benichou G, Kawai T. Alefacept promotes immunosuppression-free renal allograft survival in nonhuman primates via depletion of recipient memory T cells. Am J Transplant. 2013 Dec; 13(12):3223-9. PMID: 24165326.
    Citations: 14     Fields:    Translation:AnimalsCells
  45. Elias N, Kawai T, Ko DS, Saidi R, Tolkoff-Rubin N, Wicky S, Cosimi AB, Hertl M. Native portal vein embolization for persistent hyperoxaluria following kidney and auxiliary partial liver transplantation. Am J Transplant. 2013 Oct; 13(10):2739-42. PMID: 23915277.
    Citations: 2     Fields:    Translation:Humans
  46. Kawai T, Sachs DH. Tolerance induction: hematopoietic chimerism. Curr Opin Organ Transplant. 2013 Aug; 18(4):402-7. PMID: 23838644.
    Citations: 13     Fields:    Translation:Humans
  47. Benichou G, Nadazdin O, Cosimi AB, Kawai T. Successful tolerance to fully MHC disparate renal allografts via donor hematopoietic mixed chimerism in non-human primates. Am J Transplant. 2013 Sep; 13(9):2500. PMID: 23865775.
    Citations: 3     Fields:    Translation:Animals
  48. Kawai T, Ohishi M, Takeya Y, Onishi M, Ito N, Oguro R, Yamamoto K, Kamide K, Rakugi H. Carotid plaque score and intima media thickness as predictors of stroke and mortality in hypertensive patients. Hypertens Res. 2013 Oct; 36(10):902-9. PMID: 23823172.
    Citations: 13     Fields:    Translation:Humans
  49. Kawai T, Sachs DH, Sykes M, Cosimi AB. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med. 2013 May 09; 368(19):1850-2. PMID: 23656665.
    Citations: 67     Fields:    Translation:Humans
  50. Cosimi AB, Sachs DH, Sykes M, Kawai T. Clinical strategy for induction of transplantation tolerance through mixed chimerism. Clin Transpl. 2013; 127-34. PMID: 25095501.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  51. Tsoulfas G, Agorastou P, Ko D, Hertl M, Elias N, Cosimi AB, Kawai T. Laparoscopic living donor nephrectomy: is there a difference between using a left or a right kidney? Transplant Proc. 2012 Nov; 44(9):2706-8. PMID: 23146499.
    Citations: 3     Fields:    Translation:Humans
  52. Kawai T, Ohishi M, Takeya Y, Onishi M, Ito N, Yamamoto K, Kamide K, Rakugi H. Serum uric acid is an independent risk factor for cardiovascular disease and mortality in hypertensive patients. Hypertens Res. 2012 Nov; 35(11):1087-92. PMID: 22739421.
    Citations: 12     Fields:    Translation:Humans
  53. Aoyama A, Klarin D, Yamada Y, Boskovic S, Nadazdin O, Kawai K, Schoenfeld D, Madsen JC, Cosimi AB, Benichou G, Kawai T. Low-dose IL-2 for In vivo expansion of CD4+ and CD8+ regulatory T cells in nonhuman primates. Am J Transplant. 2012 Sep; 12(9):2532-7. PMID: 22682297.
    Citations: 11     Fields:    Translation:AnimalsCells
  54. Saidi RF, Elias N, Hertl M, Kawai T, Cosimi AB, Ko DS. Urinary reconstruction after kidney transplantation: pyeloureterostomy or ureteroneocystostomy. J Surg Res. 2013 May 01; 181(1):156-9. PMID: 22683078.
    Citations:    Fields:    Translation:Humans
  55. Yamada Y, Aoyama A, Tocco G, Boskovic S, Nadazdin O, Alessandrini A, Madsen JC, Cosimi AB, Benichou G, Kawai T. Differential effects of denileukin diftitox IL-2 immunotoxin on NK and regulatory T cells in nonhuman primates. J Immunol. 2012 Jun 15; 188(12):6063-70. PMID: 22586034.
    Citations: 12     Fields:    Translation:AnimalsCells
  56. Markmann JF, Kawai T. The quest for transplantation tolerance: have we finally sipped from the cup? Sci Transl Med. 2012 Mar 07; 4(124):124fs5. PMID: 22399262.
    Citations: 8     Fields:    Translation:Humans
  57. Yamada Y, Benichou G, Cosimi AB, Kawai T. Tolerance induction after organ transplantation, "delayed tolerance," via the mixed chimerism approach: planting flowers in a battle field. Chimerism. 2012 Jan-Mar; 3(1):24-8. PMID: 22690270.
    Citations: 3     Fields:    
  58. Tsoulfas G, Elias N, Sandberg WS, Ko DS, Kawai T, Cosimi AB, Tsitsopoulos PP, Agorastou P, Hertl M. Liver transplantation results in complete neurologic recovery from malignant hypertension secondary to fulminant hepatic failure: a case report. Ann Transplant. 2012 Jan-Mar; 17(1):117-21. PMID: 22466917.
    Citations:    Fields:    Translation:Humans
  59. Kitchens WH, Yeh H, Van Cott EM, Elias N, Kawai T, Markmann JF, Hertl M. Protein S deficiency in a living liver donor. Transpl Int. 2012 Feb; 25(2):e23-6. PMID: 22175543.
    Citations:    Fields:    Translation:Humans
  60. Yamada Y, Boskovic S, Aoyama A, Murakami T, Putheti P, Smith RN, Ochiai T, Nadazdin O, Koyama I, Boenisch O, Najafian N, Bhasin MK, Colvin RB, Madsen JC, Strom TB, Sachs DH, Benichou G, Cosimi AB, Kawai T. Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant. 2012 Feb; 12(2):330-40. PMID: 22053723.
    Citations: 50     Fields:    Translation:AnimalsCells
  61. Kawai T, Ohishi M, Kamide K, Onishi M, Takeya Y, Tatara Y, Oguro R, Yamamoto K, Sugimoto K, Rakugi H. The impact of visit-to-visit variability in blood pressure on renal function. Hypertens Res. 2012 Feb; 35(2):239-43. PMID: 22011685.
    Citations: 31     Fields:    Translation:Humans
  62. Nadazdin O, Boskovic S, Wee SL, Sogawa H, Koyama I, Colvin RB, Smith RN, Tocco G, O'Connor DH, Karl JA, Madsen JC, Sachs DH, Kawai T, Cosimi AB, Benichou G. Contributions of direct and indirect alloresponses to chronic rejection of kidney allografts in nonhuman primates. J Immunol. 2011 Nov 01; 187(9):4589-97. PMID: 21957140.
    Citations: 5     Fields:    Translation:AnimalsCells
  63. Sachs DH, Sykes M, Kawai T, Cosimi AB. Immuno-intervention for the induction of transplantation tolerance through mixed chimerism. Semin Immunol. 2011 Jun; 23(3):165-73. PMID: 21839648.
    Citations: 26     Fields:    Translation:HumansAnimals
  64. Kawai T, Cosimi AB, Sachs DH. Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant. 2011 Aug; 16(4):366-71. PMID: 21666482.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  65. Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, Locascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB. Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant. 2011 Jul; 11(7):1464-77. PMID: 21668634.
    Citations: 33     Fields:    Translation:Humans
  66. Nadazdin O, Boskovic S, Murakami T, Tocco G, Smith RN, Colvin RB, Sachs DH, Allan J, Madsen JC, Kawai T, Cosimi AB, Benichou G. Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates. Sci Transl Med. 2011 Jun 08; 3(86):86ra51. PMID: 21653831.
    Citations: 60     Fields:    Translation:AnimalsCells
  67. Kennealey PT, Elias N, Hertl M, Ko DS, Saidi RF, Markmann JF, Smoot EE, Schoenfeld DA, Kawai T. A prospective, randomized comparison of bovine carotid artery and expanded polytetrafluoroethylene for permanent hemodialysis vascular access. J Vasc Surg. 2011 Jun; 53(6):1640-8. PMID: 21609797.
    Citations: 6     Fields:    Translation:Humans
  68. Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, Locascio SA, Morokata T, Dey BR, Tolkoff-Rubin NT, Preffer F, Bonnefoix T, Kattleman K, Spitzer TR, Sachs DH, Sykes M. Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation. Am J Transplant. 2011 Jun; 11(6):1236-47. PMID: 21645255.
    Citations: 48     Fields:    Translation:Humans
  69. McCausland FR, Varma MC, Goes NB, Heher EC, Markmann JF, Cosimi AB, Elias N, Ko DS, Kawai T, Smith RN, Rubin MF. Renal allograft rupture: a strategy for graft preservation. Transplantation. 2011 May 15; 91(9):e67-9. PMID: 21508800.
    Citations:    Fields:    Translation:Humans
  70. Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi AB. Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease. Transplantation. 2011 Mar 27; 91(6):672-6. PMID: 21217460.
    Citations: 52     Fields:    Translation:Humans
  71. Kawai T, Kamide K, Onishi M, Yamamoto-Hanasaki H, Baba Y, Hongyo K, Shimaoka I, Tatara Y, Takeya Y, Ohishi M, Rakugi H. Usefulness of the resistive index in renal Doppler ultrasonography as an indicator of vascular damage in patients with risks of atherosclerosis. Nephrol Dial Transplant. 2011 Oct; 26(10):3256-62. PMID: 21372256.
    Citations: 17     Fields:    Translation:Humans
  72. Saidi RF, Hertl M, Chung RT, Ko DS, Kawai T, Markmann J, Bhan AK, Cosimi AB, Elias N. Induction with Rabbit Antithymocyte Globulin following Orthotopic Liver Transplantation for Hepatitis C. Int J Organ Transplant Med. 2011; 2(4):160-5. PMID: 25013609.
    Citations:    
  73. LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman SL, Spitzer TR, Tolkoff-Rubin N, Cosimi AB, Sachs DH, Sykes M. Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation. 2010 Dec 27; 90(12):1607-15. PMID: 21085064.
    Citations: 37     Fields:    Translation:HumansCells
  74. Saidi RF, Bradley J, Greer D, Luskin R, O'Connor K, Delmonico F, Kennealey P, Pathan F, Schuetz C, Elias N, Ko DS, Kawai T, Hertl M, Cosimi AB, Markmann JF. Changing pattern of organ donation at a single center: are potential brain dead donors being lost to donation after cardiac death? Am J Transplant. 2010 Nov; 10(11):2536-40. PMID: 21043059.
    Citations: 15     Fields:    Translation:Humans
  75. Tsoulfas G, Kawai T, Elias N, Ko SC, Agorastou P, Cosimi AB, Hertl M. Long-term experience with liver transplantation for hepatocellular carcinoma. J Gastroenterol. 2011 Feb; 46(2):249-56. PMID: 20711612.
    Citations: 6     Fields:    Translation:Humans
  76. Kawai T, Benedict Cosimi A. Induction of tolerance in clinical kidney transplantation. Clin Transplant. 2010 Jul; 24 Suppl 22:2-5. PMID: 20590685.
    Citations: 1     Fields:    Translation:Animals
  77. Nadazdin O, Boskovic S, Murakami T, O'Connor DH, Wiseman RW, Karl JA, Tuscher JJ, Sachs DH, Madsen JC, Tocco G, Kawai T, Cosimi AB, Benichou G. Phenotype, distribution and alloreactive properties of memory T cells from cynomolgus monkeys. Am J Transplant. 2010 Jun; 10(6):1375-84. PMID: 20486921.
    Citations: 35     Fields:    Translation:AnimalsCells
  78. Nadazdin O, Abrahamian G, Boskovic S, Smith RN, Schoenfeld DA, Madsen JC, Colvin RB, Sachs DH, Cosimi AB, Kawai T. Stem cell mobilization and collection for induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. J Surg Res. 2011 Jun 15; 168(2):294-300. PMID: 20605588.
    Citations: 5     Fields:    Translation:Animals
  79. Saidi RF, Wertheim JA, Kennealey P, Ko DS, Elias N, Yeh H, Hertl M, Kawai T. Donor kidney recovery methods and the incidence of lymphatic complications in kidney transplant recipients. Int J Organ Transplant Med. 2010; 1(1):40-3. PMID: 25013562.
    Citations: 1     
  80. Saidi RF, Elias N, Ko DS, Kawai T, Markmann J, Feng S, Cosimi AB, Hertl M. Live donor partial hepatectomy for liver transplantation: is there a learning curve? Int J Organ Transplant Med. 2010; 1(3):125-30. PMID: 25013578.
    Citations: 5     
  81. Saidi RF, Elias N, Ko DS, Kawai T, Markmann J, Cosimi AB, Hertl M. Biliary reconstruction and complications after living-donor liver transplantation. HPB (Oxford). 2009 Sep; 11(6):505-9. PMID: 19816615.
    Citations: 6     Fields:    
  82. Porcheray F, Wong W, Saidman SL, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant. 2009 Sep; 9(9):2126-35. PMID: 19624570.
    Citations: 28     Fields:    Translation:HumansCells
  83. Saidi R, Kawai T, Kennealey P, Tsouflas G, Elias N, Hertl M, Cosimi AB, Ko DS. Living donor kidney transplantation with multiple arteries: recent increase in modern era of laparoscopic donor nephrectomy. Arch Surg. 2009 May; 144(5):472-5. PMID: 19451491.
    Citations: 7     Fields:    Translation:Humans
  84. Aoyama A, Ng CY, Millington TM, Boskovic S, Murakami T, Wain JC, Houser SL, Madsen JC, Kawai T, Allan JS. Comparison of lung and kidney allografts in induction of tolerance by a mixed-chimerism approach in cynomolgus monkeys. Transplant Proc. 2009 Jan-Feb; 41(1):429-30. PMID: 19249572.
    Citations: 17     Fields:    Translation:Animals
  85. Murakami T, Cosimi AB, Kawai T. Mixed chimerism to induce tolerance: lessons learned from nonhuman primates. Transplant Rev (Orlando). 2009 Jan; 23(1):19-24. PMID: 19027614.
    Citations: 5     Fields:    Translation:AnimalsCells
  86. Saidi RF, Elias N, Ko DS, Kawai T, Markmann J, Cosimi AB, Hertl M. Biliary reconstruction and complications after living-liver transplantation. HPB. 2009; 11(8):505-509.
  87. Saidi RF, Kennealey PT, Elias N, Kawai T, Hertl M, Farrell M, Goes N, Hartono C, Tolkoff-Rubin N, Cosimi AB, Ko DS. Deceased donor kidney transplantation in elderly patients: is there a difference in outcomes? Transplant Proc. 2008 Dec; 40(10):3413-7. PMID: 19100401.
    Citations: 2     Fields:    Translation:Humans
  88. Traum AZ, Ko DS, Kawai T. The potential for tolerance in pediatric renal transplantation. Curr Opin Organ Transplant. 2008 Oct; 13(5):489-94. PMID: 19060531.
    Citations: 3     Fields:    Translation:Humans
  89. Sogawa H, Boskovic S, Nadazdin O, Abrahamian G, Colvin RB, Sachs DH, Cosimi AB, Kawai T. Limited efficacy and unacceptable toxicity of cyclophosphamide for the induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation. 2008 Aug 27; 86(4):615-9. PMID: 18724233.
    Citations: 3     Fields:    Translation:AnimalsCells
  90. Tsoulfas G, Hertl M, Ko DS, Elias N, Delmonico FL, Romano L, Fernandes I, Schoenfeld D, Kawai T. Long-term outcome of a cuffed expanded PTFE graft for hemodialysis vascular access. World J Surg. 2008 Aug; 32(8):1827-31. PMID: 18343971.
    Citations: 4     Fields:    Translation:Humans
  91. Sachs DH, Kawai T, Colvin RB, Fishman JA, Sykes M, Cosimi AB. Response to 'Tolerance versus immunosuppression: a perspective'. Am J Transplant. 2008 Aug; 8(8):1573-4. PMID: 18694470.
    Citations: 2     Fields:    Translation:Humans
  92. Smith RN, Kawai T, Boskovic S, Nadazdin O, Sachs DH, Cosimi AB, Colvin RB. Four stages and lack of stable accommodation in chronic alloantibody-mediated renal allograft rejection in Cynomolgus monkeys. Am J Transplant. 2008 Aug; 8(8):1662-72. PMID: 18557724.
    Citations: 36     Fields:    Translation:Animals
  93. Traum AZ, Kawai T, Vacanti JP, Sachs DH, Cosimi AB, Madsen JC. The need for tolerance in pediatric organ transplantation. Pediatrics. 2008 Jun; 121(6):1258-60. PMID: 18519497.
    Citations: 3     Fields:    Translation:Humans
  94. Saidi RF, Wertheim JA, Ko DS, Elias N, Martin H, Delmonico FL, Cosimi AB, Kawai T. Impact of donor kidney recovery method on lymphatic complications in kidney transplantation. Transplant Proc. 2008 May; 40(4):1054-5. PMID: 18555113.
    Citations: 3     Fields:    Translation:Humans
  95. Kawai T, Cosimi AB, Spitzer RT, Tolkoff-Rubin N, Suthanthiran M, Saidman SL, Shaffer J, Preffer FI, Ding R, Sharma J, Fishman JA, Bimalangshu D, Ko DSC, Hertl M, Goes NB, Wong W, Williams WW, Colvin RB, Sykes M and Sachs DH. HLA-Mismatched Renal Transplantation without Maintenance Immuno-Suppression. New Engl J Med. 2008; 358(4):353-361.
  96. Kawai T, Cosimi AB, Spitzer TR, Tolkoff-Rubin N, Suthanthiran M, Saidman SL, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Ko DS, Hertl M, Goes NB, Wong W, Williams WW, Colvin RB, Sykes M, Sachs DH. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med. 2008 Jan 24; 358(4):353-61. PMID: 18216355.
    Citations: 367     Fields:    Translation:HumansCells
  97. Dela Golshayan, A. Benedict Cosimi, Tatsuo Kawai. TOLERANCE INDUCTION TO PREVENT REJECTION. International Transplant Updates. 2008; in press.
  98. Saidi RF, Elias N, Kawai T, Hertl M, Farrell ML, Goes N, Wong W, Hartono C, Fishman JA, Kotton CN, Tolkoff-Rubin N, Delmonico FL, Cosimi AB, Ko DS. Outcome of kidney transplantation using expanded criteria donors and donation after cardiac death kidneys: realities and costs. Am J Transplant. 2007 Dec; 7(12):2769-74. PMID: 17927805.
    Citations: 45     Fields:    Translation:Humans
  99. Singh AK, Sahani DV, Kagay CR, Kalva SP, Joshi MC, Elias N, Kawai T. Semiautomated MIP images created directly on 16-section multidetector CT console for evaluation of living renal donors. Radiology. 2007 Aug; 244(2):583-90. PMID: 17641376.
    Citations: 1     Fields:    Translation:Humans
  100. Singh A, Sahani D, Kagay C, Kalva S, Elias N, Kawai T . Semi-automated MIP images created directly on 16-slice MDCT console for evaluation of living renal donors. Radiology. 2007; 244(2):583-590.
  101. Ochiai T, Benichou G, Cosimi AB, Kawai T. Induction of allograft tolerance in nonhuman primates and humans. Front Biosci. 2007 May 01; 12:4248-53. PMID: 17485371.
    Citations: 4     Fields:    Translation:HumansAnimals
  102. Koyama I, Nadazdin O, Boskovic S, Ochiai T, Smith RN, Sykes M, Sogawa H, Murakami T, Strom TB, Colvin RB, Sachs DH, Benichou G, Cosimi AB, Kawai T. Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft. Am J Transplant. 2007 May; 7(5):1055-61. PMID: 17286617.
    Citations: 65     Fields:    Translation:AnimalsCells
  103. Veronese F, Rotman S, Smith RN, Pelle TD, Farrell ML, Kawai T, Benedict Cosimi A, Colvin RB. Pathological and clinical correlates of FOXP3+ cells in renal allografts during acute rejection. Am J Transplant. 2007 Apr; 7(4):914-22. PMID: 17286616.
    Citations: 46     Fields:    Translation:HumansCells
  104. Toru Murakami, Tatsuo Kawai. [Immunological Tolerance](in Japanese). Annual Review Kidney 2007 / (Editor) Mitarai T, Higashibara E, Akisawa T, Igarashi T, Kanai Y. 2007; 173-182 .
  105. Tatsuo Kawai, David H Sachs, Thomas Spitzer, Nina Tokoff-Rubin, Francis Delmonico, Susan saidman, Juanita Shaffer, Winfred Williams, Bimlangshu Dey, Steven McAfee, Dicken Ko, Martin Hertl, Nelson Goes, waichi Wong, Jay Fishman, Robert Colvin, Megan Sykes, A Benedict Cosimi. The Long-term Evaluation of HLA-Mismatched Combined Kidney and Bone Marrow Transplant Recipients after Complete Withdrawal of Immunosuppression. Am J Transplant. 2007; 7(Supplement 2):147.
  106. Fabrice Porcheray, Ovidiu Marina, Waichi Wong, Catherine J Wu, Susan saidman, Nina Tokoff-Rubin, Bimlangshu Dey, Thomas R Spitzer, Tatsuo Kawai, A.B.Cosimi, David H Sachs, Megan Sykes, Emmanuel Zorn. B cel responses After Combined Kidney and BOne Marrow Transplantation. Am J Transplant. 2007; 7(Supplement 2):337.
  107. Ochiai T, Cosimi AB, Benichou G, Kawai T. Induction of Alograft Tolerance in Nonhuman Primates and Humans. Frontiers in Bioscience. 2007; 12:4248-4253.
  108. Kawai T, Cosimi AB, Sachs DH. Donor Bone Marrow Transplantation as An Approach to Tolerance Induction for Clinical Kidney Transplantation. Curr Opin Organ Transplant. 2007; 12(5):618-623.
  109. Murakami T and Kawai T . [What is the induction of immunological tolerance?](in Japanese). Japanese Journal of Pediatric Medicine. 2006; 38(12):2077-2082 .
  110. Boskovic S, Kawai T, Smith RN, Wee SL, Nadazdin O, Koyama I, Saidman S, Cardarelli F, Elias N, Sykes M, Strom T, Colvin RB, Sachs DH, Cosimi AB. Monitoring antidonor alloantibodies as a predictive assay for renal allograft tolerance/long-term observations in nonhuman primates. Transplantation. 2006 Sep 27; 82(6):819-25. PMID: 17006330.
    Citations: 14     Fields:    Translation:AnimalsCells
  111. Fudaba Y, Spitzer T, Shaffer J, Kawai T, Smith RN, Delmonico FL, Colvin RB, Sachs DH, Cosimi AB, Sykes M . "Split" tolerance following combined HLA-Identical Kidney And Non-Myeloablative Marrow Transplantation for Multiple Myeloma. Am J Transplant. 2006; 6(9):2121-2133.
  112. Fudaba Y, Spitzer TR, Shaffer J, Kawai T, Fehr T, Delmonico F, Preffer F, Tolkoff-Rubin N, Dey BR, Saidman SL, Kraus A, Bonnefoix T, McAfee S, Power K, Kattleman K, Colvin RB, Sachs DH, Cosimi AB, Sykes M. Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses. Am J Transplant. 2006 Sep; 6(9):2121-33. PMID: 16796719.
    Citations: 84     Fields:    Translation:Humans
  113. Smith RN, Kawai T, Boskovic S, Nadazdin O, Sachs DH, Cosimi AB, Colvin RB. Chronic antibody mediated rejection of renal allografts: pathological, serological and immunologic features in nonhuman primates. Am J Transplant. 2006 Aug; 6(8):1790-8. PMID: 16780551.
    Citations: 19     Fields:    Translation:Animals
  114. Tatsuo Kawai, David H Sachs, Thomas Spitzer, Nina Tokoff-Rubin, Francis Delmonico, Susan saidman, Juanita Shaffer, Winfred Williams, Bimlangshu Dey, Steven McAfee, Dicken Ko, Martin Hertl, Nelson Goes, waichi Wong, Jay Fishman, Robert Colvin, Megan Sykes, A Benedict Cosimi. Successful Induction of Renal Allograft Tolerance In HLA-Mismatched Kidney Transplant Recipients. World Transplant Congress 2006; Supplement to Am J Transplant and Transplantation. 2006; 169.
  115. Kawai T, Sachs DH, Sykes M, Spitzer T, Tolkoff-Rubin N, Saidman S, Ko D, Dey B, Colvin RB, Cosimi AB. My most interesting cases. Clin Transpl. 2006; 580-2. PMID: 18365443.
    Citations:    Fields:    Translation:Humans
  116. Francisco V Veronese, samuel Rotman, Neal Smith, Tatsuo Kawai, Patricia Delle Pelle, Mary Lin Farrell, A. Benedict Cosimi, Robert B Colvin. FOXP3+ T Regulatory Cells (Tregs) I Human Kidney Allograft Biopsies: Phenotype And Relation To Rejection Type, Tubulitis, And Outcome. World Transplant Congress 2006 : Supplement to Am J Transplant and Transplantation. 2006; 410.
  117. Georgios Tsoulfas, Tatsuo Kawai, Nahel Elias, Dicken SC Ko, Francis L Delmonico, AB Cosimi, Martin Hertl. Impact Of The Model For End-Stage Liver Disease (MELD)System On Survival After Liver Transplantation For Hepatocellular Carcinoma. World Transplant Congress 2006: Supplement to Am J Transplant and Transplantation. 2006; 970.
  118. Ichiro Koyama, Takanori Ochiai, Svetlan Boskovic, Ognjenka nadazdin, Mike Duggan, Neal Smith, Robert B Colvin, David H Sachs, A.Benedict Cosimi, Tatsuo Kawai . Deletion of CD8+ Memory T Cells With Humanized Anti-CD8 Mab (cM-T807) For Induction of Mixed Chimerism And Specific Tolerance Of Previously Transplanted Renal Allografts. World Transplant Congress 2006 Supplement to Am J Transplant and Transplantation. 2006; 252.
  119. Takanori Ochiai, Ichiro Koyama, Svetlan Boskovic, Ognjenka nadazdin, Mike Duggan, Neal Smith, Robert B Colvin, David H Sachs, A.Benedict Cosimi, Tatsuo Kawai . Delayed Tolerance Induction In Nonhuman Primates Renal Allograft Recipient. Am J Transplant. 2005; 5(Supplement 11):422.
  120. Nahel Elias, Martin Hertl, Tatsuo Kawai, Dicken SC Ko, Georgeos Tsoulfas, Michael Thiim, Raymond T Chung, A Benedict Cosimi. Minimizing Recurrence of hepatitis C virus (HCV) After liver Transplantation Using SteroidFree Immunosuppression And Early Anti-Viral Therapy. Am J Transplant. 2005; 5(Supplement 11):177.
  121. Tatsuo Kawai, David H Sachs, Thomas Spitzer, Nina Tokoff-Rubin, Francis Delmonico, Susan saidman, Juanita Shaffer, Winfred Williams, Bimlangshu Dey, Steven McAfee, Dicken Ko, Martin Hertl, Nelson Goes, waichi Wong, Jay Fishman, Robert Colvin, Megan Sykes, A Benedict Cosimi. Combined Kidney And Bone Marrow Transplantation For Induction of Mixed Chimerism And Renal allograft Tolerance in HLA Matched and Mismatched Recipients. Am J Transplant. 2005; 5(Supplement 11):546.
  122. Kawai T, Sogawa H, Boskovic S, Abrahamian G, Smith RN, Wee SL, Andrews D, Nadazdin O, Koyama I, Sykes M, Winn HJ, Colvin RB, Sachs DH, Cosimi AB. CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. Am J Transplant. 2004 Sep; 4(9):1391-8. PMID: 15307826.
    Citations: 89     Fields:    Translation:Animals
  123. S Boskovic, T Kawai, S L Wee, O Nadazdin, I Koyama, R N Smith, N Elias, T Ochiai, M Sykes, R B Colvin, D H Sachs, A B Cosimi. Long-term Observations in Renal Allograft Recipients Treated With A Chimerism-Inducing nonmyeloablative Regimen With CD154 Blockade. Transplantation. 2004; 78(2):43.
  124. R Neal Smith, T Kawai, S Boskovic, O Nadazdin, F Cardarelli, D J Dorer, S Saidman, D H Sachs, A B Cosimi, R B Colvin. Natural History of Chronic Humoral Rejection of Renal Allografts in A Nonhuman Primates. Transplantation. 2004; 78(2):167.
  125. J Shaffer, T Kawai, A B Cosimi, Y Fudaba, S Saidman, F Preffer, D Dombkowski, F Delmonico, S McAfee, N Tolkoff-Rubin, K Ballen, B Dey, T R Spitzer, D H Schs, M Sykes. Mechanism of Donor Specific Unresponsiveness in Tolerant Recipients of Combined Non-myeloablative HLA-Mismatched Bone Marrow and Kidney Transplantation. Transplantation. 2004; 78(2):14.
  126. M Koulamanda, R N Smith, T Kawai, G Weir, H Auchncloss, T B Strom. Islet Allograft Survival I Diabetic Monkeys After Anti-CD154, DST, And Delayed Rapamycin Treatment. Transplantation. 2004; 78(2):79.
  127. T Kawai, D H Sachs, T Spitzer, M Sykes, N Tolkof-Rubin, F Delmonico, S Saidman, J Shaffer, B Dey, S McAfee, D Ko, W Wong, W William, N Goes, M Heartl, R N Smith, R B Colvin, A B Cosimi. Combined Kidney And bone Marrow Transplantation for Inductionof Mixed Chimerism And Renal Allograft Tolerance In HLA Mismatched Transplantation. Transplantation. 2004; 78(2):43.
  128. N Elias, M Hertl, T Kawai, D SC Ko, M Thiim, R T Chung, A B Cosimi. Steroid-Free Immunosuppression and Early Preemptive Anti-Viral Therapy Results in Decreased HCV Recurrence in Liver Transplant Recipients. Transplantation. 2004; 78(2):171.
  129. Y Fudaba, JM Shaffer, A Kraus, AB Cosimi, FL Delmonico, B Dey, T Kawai, S McAfee, F Preffer, N Tolkoff-Rubin, DH Sachs, SL Saidman, TR Spitzer, M Sykes. Alloresponses In Tolerant Recipients Of Combined Kidney/Bone Marrow Transplantation With Non-Myeloabaltive Conditioning. Transplantation. 2004; 78(2):529.
  130. m Koulmanda, XX Zheng, A Quipo, R N Smith, T Kawai, N S Kenyon, G Weir, H Auchincloss, T B Strom. A Short-Term Treatment With A Combination Of IL-2/Fc And Mutant IL-15/Fc Fusion Proteins Prolonged Islet Graft Survival in Diabetic Cynomolgus Monkeys. Transplantation. 2004; 78(2):130.
  131. Kawai T, Sachs DH, et.al. . Combine kidney and bone marrow transplantation for induction of mixed chimerism and renal allograft tolerance in HLA mismatched transplantation. American Transplant Congress. 2004.
  132. Koyama I, Kawai T, Andrews D, Boskovic S, Nadazdin O, Wee SL, Sogawa H, Wu DL, Smith RN, Colvin RB, Sachs DH, Cosimi AB. Thrombophilia associated with anti-CD154 monoclonal antibody treatment and its prophylaxis in nonhuman primates. Transplantation. 2004 Feb 15; 77(3):460-2. PMID: 14966427.
    Citations: 35     Fields:    Translation:Animals
  133. A Muniappan, DR Johnston, DA Guenther, T Shoji, S Boskovic, R Hoerbelt, SL Houser, JS Alln, K Yamada, T Kawai, JC Wain, DH Sachs, JC Madsen. En-Bloc Heart And THymus Transplantation in Cynomolgus Monkeys. Transplantation . 2004; 78(2):631.
  134. I Koyam, T Kawai, SL Wee, S Boskovic, O Nadazdin, RN Smith, M Sykes, RB Colvin, DH Sach, AB Cosimi. Development of A Mixed Chimerism-TOlerance Inducing Nonmyeloablative Regimen Relevant To Cadver Donor Transplantation. Transplantation. 2004; 78(2):578.
  135. Gollackner B, Knosalla C, Houser S, Mauiyyedi S, Buhler L, Kawai T, Duggan M, Sachs DH, Awwad M, Cooper DK. Pig kidney transplantation in baboons treated intravenously with a bovine serum albumin-Galalpha1-3Gal conjugate. Xenotransplantation. 2003 Nov; 10(6):606-14. PMID: 14708529.
    Citations: 3     Fields:    Translation:HumansAnimals
  136. Gollackner B, Dor FJ, Knosalla C, Buhler L, Duggan M, Huang CA, Houser SL, Sachs DH, Kawai T, Ko DS, Cooper DK. Spleen transplantation in miniature swine: surgical technique and results in major histocompatibility complex-matched donor and recipient pairs. Transplantation. 2003 Jun 15; 75(11):1799-806. PMID: 12811237.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  137. Kawai T, Wee SL, et. al. . In vitro monitoring of renal allograft tolerance induced by mixed chimerism and costimulatory blockade in nonhuman primates. American Society of Transplant Surgeons. 2003.
  138. Frank J Dor, Bernd Gollackner, Kenji Kuwaki, Derek Prabharasuth, Amy Alt, Stuart Houser, Christoph Knosalla, Mike Duggan, Tatsu Kawai, Dicken SC Ko, David KC Cooper. Donor Specific Unresponsiveness and Mixed Hematopoietic Chimerism Following Allogeneic Spllen Transplantation in Miniature Swine. Am J Transplant. 2003; 3(Supplement 5):263.
  139. Maria Koulmanda, Andi Quipo, Rex N Smith, Tatsuo Kawai, Jack Oneal, Ichiro Koyama, Gordon Weir, Hugh Auchincloss, Terry B Strom. Islet Allograft Survival in Diabetic Monkeys After Anti-CD154, DST, and Sirolimus Treatment. Am J Transplant. 2003; 3(Supplement 5):393.
  140. Yasuhiro Fudaba, Juanita M Shaffer, Annett Krau, A Benedic Cosimi, Francis Delmonico, Bimalangshu Dey, Tatsuo Kawai, Steven McAfee, Frederic Preffer, Nina Tolkoff-Rubin, David H Sachs, Susan L Saidman, Thomas R Spitzer, Megan Sykes. Alloresponses in Tolerant recipients of Combined Kidney /Bone Marrow Transplantation with Nonmyeloablative Conditioning. Am J Transplant. 2003; 3(Supplement 5):316.
  141. O'Neil JJ, Tchipashvili V, Parent RJ, Ugochukwu O, Chandra G, Koulmanda M, Ko D, Kawai T. A simple and cost-effective method for the isolation of islets from nonhuman primates. Cell Transplant. 2003; 12(8):883-90. PMID: 14763508.
    Citations: 9     Fields:    Translation:HumansAnimals
  142. Kawai T, Sachs D, Colvin RB, Cosimi AB. Induction of Allograft Tolerance in Primates-macaque to human. Immunitas. 2003; 6(Fall):2-3.
  143. Rex N Smith, Tatsuo Kawai, Svetlan Boskovic, Ognjenka Nadazdin, Ichiro Koyama, Patricia Della Pelle, A Benedic Cosimi, Robert B Colvin. Chronic Humoral Rejection in Renal allografts in Cynomolgus Monkeys on Mixed Chimerism: Correlation of C4D, Alloantibody, and Chronic Allograft Arteriopathy and Glomerulopathy. Am J Transplant. 2003; 3(Supplement 5):316.
  144. Tatsuo Kawai, Siew Lin Wee, Svetlan Boskovic, Ichiro Koyama, Ognjenka Nadazdin, Matthew Nuhn, R Neal Smith, Megan Sykes, Robert B Colvin, David H Sachs, A Benedict Cosimi. In Vitro Monitoring of Renal Allograft Tolerance Induced by Mixed Chimerismand Costimulatory Blockade in Nonhuman Primates. Am J Transplant. 2003; 3(Supplement 5):536.
  145. M Koulmanda, A Quipo, RN Smith, T Kawai, JJ Oneal, I Koyama, S Chebrolu, GC Weir, H Auchincloss, TB Strom. Prolongation of Pancreatic Islet Allograft Survival in Diabetic Cynomolgus Monkeys. Transplantation. 2002; 74(4):161.
  146. T Kawai, H Sogawa, SL Wee, S Boskovic, I Koyama, O Nadazdin, D Andrew, G Abrahamian, RN Smith, M. Sykes, RB Colvin, DH Sachs, AB Cosimi . CD154 Blockade for Induction of Mixed chimerism and Renal Allograft Tolerance in Nonhuman Primates. Transplantation. 2002; 74(4):173.
  147. Kawai T, Cosimi AB, Wee SL, Houser S, Andrews D, Sogawa H, Phelan J, Boskovic S, Nadazdin O, Abrahamian G, Colvin RB, Sach DH, Madsen JC. Effect of mixed hematopoietic chimerism on cardiac allograft survival in cynomolgus monkeys. Transplantation. 2002 Jun 15; 73(11):1757-64. PMID: 12084998.
    Citations: 40     Fields:    Translation:Animals
  148. Schmidtko J, Wang R, Wu CL, Mauiyyedi S, Harris NL, Della Pelle P, Brousaides N, Zagachin L, Ferry JA, Wang F, Kawai T, Sachs DH, Cosimi BA, Colvin RB. Posttransplant lymphoproliferative disorder associated with an Epstein-Barr-related virus in cynomolgus monkeys. Transplantation. 2002 May 15; 73(9):1431-9. PMID: 12023621.
    Citations: 12     Fields:    Translation:AnimalsCells
  149. Kawai T. [Induction of tolerance in allogeneic transplantation: New approaches and the perspectives](in Japanese). Transplantation Now. 2002; 15(3):236-242 .
  150. Pascual M, Theruvath T, Kawai T, Tolkoff-Rubin N, Cosimi AB. Strategies to improve long-term outcomes after renal transplantation. N Engl J Med. 2002 Feb 21; 346(8):580-90. PMID: 11856798.
    Citations: 141     Fields:    Translation:Humans
  151. Kawai T, Sogawa H, Wee SL, Boskovic S, Nadazdin O, Koyama I, Smith RN, Sykes M, Colvin RB, Sachs DH, Cosimi AB. Mixed Chimerism and CD154 Blockade for Renal Allograft Tolerance in Nonhuman Primates. Am J Transplant. 2002; Supplement 3(2):145.
  152. Kawai T, Sogawa H, Koulmanda M, Smith RN, O'Neil JJ, Wee SL, Boskovic S, Sykes M, Colvin RB, Sachs DH, Auchincloss H, Cosimi AB, C Ko DS. Long-term islet allograft function in the absence of chronic immunosuppression: a case report of a nonhuman primate previously made tolerant to a renal allograft from the same donor. Transplantation. 2001 Jul 27; 72(2):351-4. PMID: 11477369.
    Citations: 9     Fields:    Translation:Animals
  153. Kawai T, Abrahamian G, Sogawa H, Wee S, Boskovic S, Andrew D, Nadazdin O, Mauiyyedi S, Weymouth D, Ko D, Colvin R, Sachs D, Cosimi A. Costimulatory blockade for induction of mixed chimerism and renal allograft tolerance in nonhuman primates. Transplant Proc. 2001 Feb-Mar; 33(1-2):221-2. PMID: 11266787.
    Citations: 8     Fields:    Translation:Animals
  154. Sogawa H, Kawai T, Wee SL, Boskovic S, Nadazdin O, Phelan J, Abrahamian G, Ko DS, Hong H, Mauiyyedi S, Colvin RB, Sachs DH, Cosimi AB. Comparison of horse antithymocyte globulin with other T cell-depleting antibodies for induction of chimerism and renal allograft tolerance in nonhuman primates. Transplant Proc. 2001 Feb-Mar; 33(1-2):116-7. PMID: 11266735.
    Citations: 1     Fields:    Translation:AnimalsCells
  155. Kawai T, Sogawa H, et.al. . Long-term results of CD154 blockade for renal allograft tolerance in nonhuman primates. Am J Transplant. 2001; 1(supple):275.
  156. Bühler L, Basker M, Alwayn IP, Goepfert C, Kitamura H, Kawai T, Gojo S, Kozlowski T, Ierino FL, Awwad M, Sachs DH, Sackstein R, Robson SC, Cooper DK. Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates. Transplantation. 2000 Nov 15; 70(9):1323-31. PMID: 11087147.
    Citations: 38     Fields:    Translation:HumansAnimals
  157. Nagao Kubo, Tatsuo Kawai. [Neurosurgical disease in dialysis patient]. Surgery of Renal Failure, Pathophysiology and Management (Editor/Kazuo Ota). 2000; 344-349.
  158. Tatsuo Kawai. Hepatobiliry disease in dialysis patient(in Japanese). Surgery of Renal Failure. Pathophysiology and Management (Editor/ Kazuo Ota). 2000; 186-188.
  159. Alwayn IP, Buhler L, Basker M, Goepfert C, Kawai T, Kozlowski T, Ierino F, Sachs DH, Sackstein R, Robson SC, Cooper DK. Coagulation/thrombotic disorders associated with organ and cell xenotransplantation. Transplant Proc. 2000 Aug; 32(5):1099. PMID: 10936376.
    Citations:    Fields:    Translation:Animals
  160. Kawai T, Wee SL, Bazin H, Latinne D, Phelan J, Boskovic S, Ko DS, Hong HZ, Mauiyyedi S, Nadazdin O, Abrahamian G, Preffer F, Colvin RB, Sachs DH, Cosimi AB. Association of natural killer cell depletion with induction of mixed chimerism and allograft tolerance in non-human primates. Transplantation. 2000 Jul 27; 70(2):368-74. PMID: 10933165.
    Citations: 8     Fields:    Translation:AnimalsCells
  161. Kawai T, Sogawa H, Koulmanda M, Oneal J, Wee SL, Smith RN, Hong H, Wu D, Colvin RB, Sachs DH Auchincloss H, Cosimi AB. . Successful Induction of Tolerance of Pancreatic Islets Between MHC-Mismatched Nonhuman Primates. Transplantation. 2000; 69(8):S304.
  162. Sogawa H, Kawai T, Wee S, Boskovic S, Abrahamian G, Ko DSC, Hon H, Winn H, Colvin RB, Sachs DH, Cosimi AB. Comparison of horse anti-thymocyte globulin with other T cell depleting agents for induction of chimerism and allograft tolerance. Transplantation. 2000; 69(8):S246.
  163. Kawai T, Andrews D, Colvin RB, Sachs DH, Cosimi AB. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat Med. 2000 Feb; 6(2):114. PMID: 10655072.
    Citations: 173     Fields:    Translation:Animals
  164. Kawai T, Andrews D, Colvin RB, Sachs DH, Cosimi AB. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand Nat Med. 2000 Feb; 6(2):114. PMID: 10655073.
    Citations:    Fields:    
  165. Kawai T, Poncelet A, Sachs DH, Mauiyyedi S, Boskovic S, Wee SL, Ko DS, Bartholomew A, Kimikawa M, Hong HZ, Abrahamian G, Colvin RB, Cosimi AB. Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance. Transplantation. 1999 Dec 15; 68(11):1767-75. PMID: 10609955.
    Citations: 56     Fields:    Translation:Animals
  166. Kawai T, Sachs DH, Cosimi AB. Tolerance to vascularized organ allografts in large-animal models. Curr Opin Immunol. 1999 Oct; 11(5):516-20. PMID: 10508708.
    Citations: 7     Fields:    Translation:AnimalsCells
  167. Mourad GJ, Preffer FI, Wee SL, Powelson JA, Kawai T, Delmonico FL, Knowles RW, Cosimi AB, Colvin RB. Humanized IgG1 and IgG4 anti-CD4 monoclonal antibodies: effects on lymphocytes in the blood, lymph nodes, and renal allografts in cynomolgus monkeys. Transplantation. 1998 Mar 15; 65(5):632-41. PMID: 9521196.
    Citations: 7     Fields:    Translation:HumansAnimals
  168. Tanabe K, Takahashi K, Sonda K, Tokumoto T, Ishikawa N, Kawai T, Fuchinoue S, Oshima T, Yagisawa T, Nakazawa H, Goya N, Koga S, Kawaguchi H, Ito K, Toma H, Agishi T, Ota K. Long-term results of ABO-incompatible living kidney transplantation: a single-center experience. Transplantation. 1998 Jan 27; 65(2):224-8. PMID: 9458019.
    Citations: 24     Fields:    Translation:Humans
  169. Tanabe K, Tokumoto T, Ishikawa N, Koyama I, Takahashi K, Fuchinoue S, Kawai T, Koga S, Yagisawa T, Toma H, Ota K, Nakajima H. Comparative study of cytomegalovirus (CMV) antigenemia assay, polymerase chain reaction, serology, and shell vial assay in the early diagnosis and monitoring of CMV infection after renal transplantation. Transplantation. 1997 Dec 27; 64(12):1721-5. PMID: 9422409.
    Citations: 15     Fields:    Translation:Humans
  170. Kimikawa M, Sachs DH, Colvin RB, Bartholomew A, Kawai T, Cosimi AB. Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys. Transplantation. 1997 Sep 15; 64(5):709-16. PMID: 9311707.
    Citations: 34     Fields:    Translation:Animals
  171. Abe M, Kawai T, Futatsuyama K, Tanabe K, Fuchinoue S, Teraoka S, Toma H, Ota K. Postoperative production of anti-donor antibody and chronic rejection in renal transplantation. Transplantation. 1997 Jun 15; 63(11):1616-9. PMID: 9197356.
    Citations: 9     Fields:    Translation:HumansCells
  172. Tatsuo Kawai. [Surgical treatment for secondary hyperparathyroidism](in Japanese). Dialysis Treatment Memo (Editor/Kazuo Ota). 1997; 177-179.
  173. Iguchi Y, Tanabe K, Yagisawa T, Fuchinoue S, Kawai T, Kawaguchi H, Takahashi K, Ito K, Toma H, Agishi T, Ota K. Plasmapheresis for prevention of recurrent focal segmental glomerulosclerosis of kidney allograft in adult recipients. Ther Apher. 1997 May; 1(2):191-4. PMID: 10225770.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  174. Tatsuo Kawai. [Immunosuppressants for renal transplantation](in Japanese). Treatment of Renal Failure (Editor/Kazuo Ota). 1997; 328-332 .
  175. Tatsuo Kawai. Induction of Immunological Tolerance (in Japanese). Treatment of Renal Failure (Editor/ Kazuo Ota). 1997; 333-339.
  176. Fuchinoue W, Tanaka K, Takasaki K, Hashimoto E, Kawai T, Nakajma I, Nakagawa Y, Fujta S, Akamatsu M, Kitajima K, Hayashi N, Ota K. Living-related liver transplantation for fulminant hepatic failure. Transplant Proc. 1997 Feb-Mar; 29(1-2):424-7. PMID: 9123064.
    Citations: 3     Fields:    Translation:Humans
  177. Tanabe K, Kobayashi C, Takahashi K, Sonda K, Tokumoto T, Ishikawa N, Koga S, Naito T, Kawai T, Fuchinoue S, Yagisawa T, Goya N, Nakazawa H, Kawaguchi H, Ito K, Agishi T, Toma H, Ota K. Long-term renal function after pregnancy in renal transplant recipients. Transplant Proc. 1997 Feb-Mar; 29(1-2):1567-8. PMID: 9123427.
    Citations: 1     Fields:    Translation:Humans
  178. Kawai T, Sachs DH, Hoshino T, Koga S, Tanabe K, Toma H, Ota K, Colvin RB, Cosimi AB. Graft-vs-host tolerance in mixed allogeneic chimerism. Transplant Proc. 1997 Feb-Mar; 29(1-2):1222-3. PMID: 9123283.
    Citations: 1     Fields:    Translation:AnimalsCells
  179. Kimikawa M, Kawai T, Sachs DH, Colvin RB, Bartholomew A, Cosimi AB. Mixed chimerism and transplantation tolerance induced by a nonlethal preparative regimen in cynomolgus monkeys. Transplant Proc. 1997 Feb-Mar; 29(1-2):1218. PMID: 9123281.
    Citations: 5     Fields:    Translation:Animals
  180. Ishida H, Kawai T, Tanabe K, Hayasaka Y, Yasuo M, Toma H, Ota K. Status of microchimerism in recipients 15 years after living related kidney transplantation. Transplantation. 1996 Jul 15; 62(1):126-8. PMID: 8693527.
    Citations: 2     Fields:    Translation:Humans
  181. Tokumoto T, Tanabe K, Sonda K, Koga S, Gouya N, Yagisawa T, Nakazawa H, Kawai T, Fuchinoue S, Teraoka S, Takahashi K, Toma H, Ota K. Effect of interferon (IFN-alpha) for prevention of hepatitis C transmission from a seropositive donor to a seronegative recipient in renal transplantation. Transplant Proc. 1996 Jun; 28(3):1503-4. PMID: 8658760.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  182. Tanabe K, Koga S, Takahashi K, Sonda K, Tokumoto T, Babazono T, Yagisawa T, Toma H, Kawai T, Fuchinoue S, Teraoka S, Ota K. Diabetes mellitus after renal transplantation under FK 506 (tacrolimus) as primary immunosuppression. Transplant Proc. 1996 Jun; 28(3):1304-5. PMID: 8658670.
    Citations:    Fields:    Translation:Humans
  183. Tanabe K, Takahashi K, Sonda K, Tokumoto T, Koga S, Nakazawa H, Goya N, Yagisawa T, Fuchinoue S, Kawai T, Toma H, Ota K. Long-term results of OKT3-treated renal transplant recipients. Transplant Proc. 1996 Jun; 28(3):1350-1. PMID: 8658689.
    Citations:    Fields:    Translation:Humans
  184. Tanabe K, Takahashi K, Koyama I, Sonda K, Fuchinoue S, Kawai T, Tokumoto T, Koga S, Naito T, Yagisawa T, Toma H, Ota K, Nakajima H. Early diagnosis of CMV syndrome after kidney transplantation: comparison between CMV antigenemia and PCR assay. Transplant Proc. 1996 Jun; 28(3):1508-10. PMID: