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profileThomas Heldt, Ph.D.

TitleMember of the Harvard-MIT Health Sciences and Technology Faculty
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology
AddressMassachusetts Institute Of Technology
E25-324a
77 Massachusetts Ave
Cambridge MA 02139
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Noraky J, Verghese GC, Searls DE, Lioutas VA, Sonni S, Thomas A, Heldt T. Noninvasive Intracranial Pressure Determination in Patients with Subarachnoid Hemorrhage. Acta Neurochir Suppl. 2016; 122:65-8. PMID: 27165879.
    View in: PubMed
  2. Dunitz M, Verghese G, Heldt T. Predicting hyperlactatemia in the MIMIC II database. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:985-8. PMID: 26736429.
    View in: PubMed
  3. Mieloszyk RJ, Guo MG, Verghese GC, Andolfatto G, Heldt T, Krauss BS. Clustering of capnogram features to track state transitions during procedural sedation. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:1699-702. PMID: 26736604.
    View in: PubMed
  4. Prasad V, Toschi N, Canichella A, Marcellucci M, Coniglione F, Dauri M, Guerrisi M, Heldt T. Intraoperative hemodynamics predict postoperative mortality in orthotopic liver transplantation. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:989-92. PMID: 26736430.
    View in: PubMed
  5. Abid A, Mieloszyk RJ, Verghese GC, Krauss BS, Heldt T. Model-based estimation of pulmonary compliance and resistance parameters from time-based capnography. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:1687-90. PMID: 26736601.
    View in: PubMed
  6. Mieloszyk RJ, Verghese GC, Deitch K, Cooney B, Khalid A, Mirre-Gonzalez MA, Heldt T, Krauss BS. Automated quantitative analysis of capnogram shape for COPD-normal and COPD-CHF classification. IEEE Trans Biomed Eng. 2014 Dec; 61(12):2882-90. PMID: 24967981.
    View in: PubMed
  7. Subramaniam B, Khabbaz KR, Heldt T, Lerner AB, Mittleman MA, Davis RB, Goldberger AL, Costa MD. Blood pressure variability: can nonlinear dynamics enhance risk assessment during cardiovascular surgery? J Cardiothorac Vasc Anesth. 2014 Apr; 28(2):392-7. PMID: 24508020; PMCID: PMC4042180.
  8. Ranger M, Celeste Johnston C, Rennick JE, Limperopoulos C, Heldt T, du Plessis AJ. A multidimensional approach to pain assessment in critically ill infants during a painful procedure. Clin J Pain. 2013 Jul; 29(7):613-20. PMID: 23328334; PMCID: PMC3640737.
  9. Reisner AT, Heldt T. A computational model of hemorrhage and dehydration suggests a pathophysiological mechanism: Starling-mediated protein trapping. Am J Physiol Heart Circ Physiol. 2013 Feb 15; 304(4):H620-31. PMID: 23203962.
    View in: PubMed
  10. Shim EB, Heldt T, Amano A, Rhee K. Computational analysis of cardiovascular hemodynamics. Comput Math Methods Med. 2012; 2012:260396. PMID: 22991576; PMCID: PMC3443616.
  11. Kashif FM, Verghese GC, Novak V, Czosnyka M, Heldt T. Model-based noninvasive estimation of intracranial pressure from cerebral blood flow velocity and arterial pressure. Sci Transl Med. 2012 Apr 11; 4(129):129ra44. PMID: 22496546; PMCID: PMC4010388.
  12. Heldt T, Kashif FM, Sulemanji M, O'Leary HM, du Plessis AJ, Verghese GC. Continuous quantitative monitoring of cerebral oxygen metabolism in neonates by ventilator-gated analysis of NIRS recordings. Acta Neurochir Suppl. 2012; 114:177-80. PMID: 22327688; PMCID: PMC3324313.
  13. Saeed M, Villarroel M, Reisner AT, Clifford G, Lehman LW, Moody G, Heldt T, Kyaw TH, Moody B, Mark RG. Multiparameter Intelligent Monitoring in Intensive Care II: a public-access intensive care unit database. Crit Care Med. 2011 May; 39(5):952-60. PMID: 21283005; PMCID: PMC3124312.
  14. Haslam B, Gordhandas A, Ricciardi C, Verghese G, Heldt T. Distilling clinically interpretable information from data collected on next-generation wearable sensors. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1729-32. PMID: 22254660; PMCID: PMC3771867.
  15. He DD, Winokur ES, Heldt T, Sodini CG. The ear as a location for wearable vital signs monitoring. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:6389-92. PMID: 21096700.
    View in: PubMed
  16. Heldt T, Verghese GC. Model-based data integration in clinical environments. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:5209-12. PMID: 21095826; PMCID: PMC3786862.
  17. Heldt T, Mukkamala R, Moody GB, Mark RG. CVSim: An Open-Source Cardiovascular Simulator for Teaching and Research. Open Pacing Electrophysiol Ther J. 2010; 3:45-54. PMID: 21949555.
    View in: PubMed
  18. Sun JX, Reisner AT, Saeed M, Heldt T, Mark RG. The cardiac output from blood pressure algorithms trial. Crit Care Med. 2009 Jan; 37(1):72-80. PMID: 19112280; PMCID: PMC3107992.
  19. Heldt T. Continuous blood pressure-derived cardiac output monitoring--should we be thinking long term? J Appl Physiol (1985). 2006 Aug; 101(2):373-4. PMID: 16690788.
    View in: PubMed
  20. Roberts JM, Parlikar TA, Heldt T, Verghese GC. Bayesian networks for cardiovascular monitoring. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:205-9. PMID: 17946804.
    View in: PubMed
  21. Heldt T, Long B, Verghese GC, Szolovits P, Mark RG. Integrating data, models, and reasoning in critical care. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:350-3. PMID: 17946818.
    View in: PubMed
  22. Heldt T, Chang JL, Chen JJ, Verghese GC, Mark RG. Cycle-averaged dynamics of a periodically driven, closed-loop circulation model. Control Eng Pract. 2005 Sep; 13(9):1163-71. PMID: 16050064.
    View in: PubMed
  23. Heldt T, Shim EB, Kamm RD, Mark RG. Computational modeling of cardiovascular response to orthostatic stress. J Appl Physiol (1985). 2002 Mar; 92(3):1239-54. PMID: 11842064.
    View in: PubMed
  24. Heldt T, Shim EB, Kamm RD, Mark RG. Model-based parameter estimation using cardiovascular response to orthostatic stress. Comput Cardiol. 2001; 28:337-40. PMID: 14640093.
    View in: PubMed
  25. Heldt T, Shim EB, Kamm RD, Mark RG. Computational model of cardiovascular function during orthostatic stress. Comput Cardiol. 2000; 27:777-80. PMID: 11806418.
    View in: PubMed
  26. Shim EB, Kamm RD, Heldt T, Mark RG. Numerical analysis of blood flow through a stenosed artery using a coupled, multiscale simulation method. Comput Cardiol. 2000; 27:219-22. PMID: 12085933.
    View in: PubMed
  27. Heldt T, Shim EB, Kamm RD, Mark RG. Computational models of cardiovascular function for analysis of post-flight orthostatic intolerance. Comput Cardiol. 1999; 26:213-6. PMID: 11795340.
    View in: PubMed
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