Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

HMS faculty, help us improve the algorithms in Profiles by uploading your CV!

Sarah Merritt Fortune, M.D.

Profile Picture
Other Positions

Columbia University, College of Physicians and SurgeonsM.D.1996Medicine
Yale UniversityB.S.1990Biology
HSPHPost Doc2006Immunology & Infectious Diseases - 5years Postdoctoral Fellow
Brigham and Women’s Hospital20003years Internship/Residency in Internal Medicine
Brigham and Women’s Hospital20011year Clinical Fellowship in Infectious Diseases


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 1P01AI143575-01A1 (RUBIN ERIC) Jun 12, 2020 - May 31, 2025
    Pathway Analysis in Tuberculosis
    Role Description: The goal of this project is to understand key pathways in Mtb biology using advanced genetic, genomic and biochemical methods, and the gold-standard in vitro and in vivo systems developed in our labs to mimic critical aspects of human TB.
    Role: Multi PI
  2. 75N93019C00071 (FORTUNE S.) Sep 1, 2019 - Sep 29, 2026
    Immune Mechanisms of Protection against Mycobacterium tuberculosis Center (IMPAc-TB)
    Role Description: The goal of this project is to apply the tools of systems immunology to exclusive animal and human models of protection from Mtb infection and disease progression.
    Role: Principal Investigator
  3. U19 AI142793 (MURRAY MEGAN) Apr 18, 2019 - Mar 31, 2024
    Bacterial Determinants of Treatment Response in Mycobacteria Tuberculosis
    Role Description: Effective control of drug-resistant TB requires the early diagnosis and treatment to prevent further transmission of the disease. Through this program, we aim to develop tools to detect drug resistant TB and improve patient outcomes.
    Role: Co-Investigator
  4. R01AI143788 (FLYNN JOANN) Feb 6, 2019 - Jan 31, 2024
    University of Pittsburgh/NIH/NIAID
    Development of a self-inactivating, highly effective TB vaccine
    Role Description: The goal of to generate and characterize candidate vaccine strains of M. bovis BCG that are conditionally replicating.
    Role: Co-Investigator
  5. R01 AI135629 (EHRT S. FORTUNE S.) Sep 1, 2018 - Aug 31, 2023
    Weill Medical College of Cornell University
    Conditionally replicating Mycobacterium tuberculosis vaccines
    Role Description: The goal of this project to develop and test candidate vaccine strains of Mycobacterium tuberculosis (Mtb), develop strains of Mtb that are dependent on an unnatural amino acid system for growth (i.e. the bacteria will not grow without the exogenous supplementation of an unnatural amino acid).
    Role: Co-Principal Investigator

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Martini MC, Hicks ND, Xiao J, Alonso MN, Barbier T, Sixsmith J, Fortune SM, Shell SS. Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis. PLoS Pathog. 2022 07; 18(7):e1010705. PMID: 35830479; PMCID: PMC9312406.
    Citations:    Fields:    Translation:Cells
  2. Tomasi FG, Hall AMJ, Schweber JTP, Dulberger CL, McGowen K, Liu Q, Fortune SM, Helaine S, Rubin EJ. A tRNA-Acetylating Toxin and Detoxifying Enzyme in Mycobacterium tuberculosis. Microbiol Spectr. 2022 06 29; 10(3):e0058022. PMID: 35638832; PMCID: PMC9241777.
    Citations:    Fields:    Translation:HumansCells
  3. Gideon HP, Hughes TK, Tzouanas CN, Wadsworth MH, Tu AA, Gierahn TM, Peters JM, Hopkins FF, Wei JR, Kummerlowe C, Grant NL, Nargan K, Phuah JY, Borish HJ, Maiello P, White AG, Winchell CG, Nyquist SK, Ganchua SKC, Myers A, Patel KV, Ameel CL, Cochran CT, Ibrahim S, Tomko JA, Frye LJ, Rosenberg JM, Shih A, Chao M, Klein E, Scanga CA, Ordovas-Montanes J, Berger B, Mattila JT, Madansein R, Love JC, Lin PL, Leslie A, Behar SM, Bryson B, Flynn JL, Fortune SM, Shalek AK. Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control. Immunity. 2022 05 10; 55(5):827-846.e10. PMID: 35483355; PMCID: PMC9122264.
    Citations: 3     Fields:    Translation:AnimalsCells
  4. Moriarty RV, Rodgers MA, Ellis AL, Balgeman AJ, Larson EC, Hopkins F, Chase MR, Maiello P, Fortune SM, Scanga CA, O'Connor SL. Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis. Microbiol Spectr. 2022 06 29; 10(3):e0172421. PMID: 35467372; PMCID: PMC9241861.
    Citations:    Fields:    Translation:AnimalsCells
  5. Carey AF, Wang X, Cicchetti N, Spaulding CN, Liu Q, Hopkins F, Brown J, Sixsmith J, Sutiwisesak R, Behar SM, Ioerger TR, Fortune SM. Multiplexed Strain Phenotyping Defines Consequences of Genetic Diversity in Mycobacterium tuberculosis for Infection and Vaccination Outcomes. mSystems. 2022 Jun 28; 7(3):e0011022. PMID: 35430871; PMCID: PMC9239107.
  6. Babunovic GH, DeJesus MA, Bosch B, Chase MR, Barbier T, Dickey AK, Bryson BD, Rock JM, Fortune SM. CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A. mBio. 2022 Jan 18; e0368321. PMID: 35038923; PMCID: PMC8764544.
    Citations: 1     Fields:    
  7. Rosenberg JM, Peters JM, Hughes T, Lareau CA, Ludwig LS, Massoth LR, Austin-Tse C, Rehm HL, Bryson B, Chen YB, Regev A, Shalek AK, Fortune SM, Sykes DB. JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia. Med (N Y). 2022 01 14; 3(1):42-57.e5. PMID: 35590143; PMCID: PMC9123284.
    Citations: 1     Translation:HumansCells
  8. Zhu J, Wolf ID, Dulberger CL, Won HI, Kester JC, Judd JA, Wirth SE, Clark RR, Li Y, Luo Y, Gray TA, Wade JT, Derbyshire KM, Fortune SM, Rubin EJ. Spatiotemporal localization of proteins in mycobacteria. Cell Rep. 2021 12 28; 37(13):110154. PMID: 34965429; PMCID: PMC8861988.
    Citations: 2     Fields:    Translation:Cells
  9. Lai Y, Cui L, Babunovic GH, Fortune SM, Doench JG, Lu TK. High-Throughput CRISPR Screens To Dissect Macrophage-Shigella Interactions. mBio. 2021 12 21; 12(6):e0215821. PMID: 34933448; PMCID: PMC8689513.
    Citations:    Fields:    Translation:HumansCells
  10. Irvine EB, O'Neil A, Darrah PA, Shin S, Choudhary A, Li W, Honnen W, Mehra S, Kaushal D, Gideon HP, Flynn JL, Roederer M, Seder RA, Pinter A, Fortune S, Alter G. Robust IgM responses following intravenous vaccination with Bacille Calmette-Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques. Nat Immunol. 2021 12; 22(12):1515-1523. PMID: 34811542; PMCID: PMC8642241.
    Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
  11. Fischinger S, Cizmeci D, Shin S, Davies L, Grace PS, Sivro A, Yende-Zuma N, Streeck H, Fortune SM, Lauffenburger DA, Naidoo K, Alter G. A Mycobacterium tuberculosis Specific IgG3 Signature of Recurrent Tuberculosis. Front Immunol. 2021; 12:729186. PMID: 34630406.
    Citations: 2     Fields:    Translation:HumansCells
  12. Culviner PH, Nocedal I, Fortune SM, Laub MT. Global Analysis of the Specificities and Targets of Endoribonucleases from Escherichia coli Toxin-Antitoxin Systems. mBio. 2021 10 26; 12(5):e0201221. PMID: 34544284; PMCID: PMC8546651.
    Citations: 4     Fields:    Translation:Cells
  13. Rokicki CAZ, Brenner JR, Dills AH, Judd JJ, Kester JC, Puffal J, Sparks IL, Prithviraj M, Anderson BR, Wade JT, Gray TA, Derbyshire KM, Fortune SM, Morita YS. Fluorescence Imaging-Based Discovery of Membrane Domain-Associated Proteins in Mycobacterium smegmatis. J Bacteriol. 2021 10 25; 203(22):e0041921. PMID: 34516286; PMCID: PMC8544410.
    Citations:    Fields:    Translation:Cells
  14. Grace PS, Dolatshahi S, Lu LL, Cain A, Palmieri F, Petrone L, Fortune SM, Ottenhoff THM, Lauffenburger DA, Goletti D, Joosten SA, Alter G. Antibody Subclass and Glycosylation Shift Following Effective TB Treatment. Front Immunol. 2021; 12:679973. PMID: 34290702.
    Citations: 4     Fields:    Translation:HumansCells
  15. Judd JA, Canestrari J, Clark R, Joseph A, Lapierre P, Lasek-Nesselquist E, Mir M, Palumbo M, Smith C, Stone M, Upadhyay A, Wirth SE, Dedrick RM, Meier CG, Russell DA, Dills A, Dove E, Kester J, Wolf ID, Zhu J, Rubin ER, Fortune S, Hatfull GF, Gray TA, Wade JT, Derbyshire KM. A Mycobacterial Systems Resource for the Research Community. mBio. 2021 03 02; 12(2). PMID: 33653882.
    Citations: 5     Fields:    Translation:Cells
  16. Kester JC, Kandror O, Akopian T, Chase MR, Zhu J, Rubin EJ, Goldberg AL, Fortune SM. ClpX Is Essential and Activated by Single-Strand DNA Binding Protein in Mycobacteria. J Bacteriol. 2021 01 25; 203(4). PMID: 33229461.
    Citations: 2     Fields:    Translation:Cells
  17. Hicks ND, Giffen SR, Culviner PH, Chao MC, Dulberger CL, Liu Q, Stanley S, Brown J, Sixsmith J, Wolf ID, Fortune SM. Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis. PLoS Pathog. 2020 11; 16(11):e1009063. PMID: 33253310.
    Citations: 6     Fields:    Translation:HumansCells
  18. Lu LL, Das J, Grace PS, Fortune SM, Restrepo BI, Alter G. Antibody Fc Glycosylation Discriminates Between Latent and Active Tuberculosis. J Infect Dis. 2020 11 13; 222(12):2093-2102. PMID: 32060529.
    Citations: 19     Fields:    Translation:HumansCells
  19. Sutiwisesak R, Hicks ND, Boyce S, Murphy KC, Papavinasasundaram K, Carpenter SM, Boucau J, Joshi N, Le Gall S, Fortune SM, Sassetti CM, Behar SM. A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response. PLoS Pathog. 2020 10; 16(10):e1009000. PMID: 33075106; PMCID: PMC7597557.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  20. Lai Y, Babunovic GH, Cui L, Dedon PC, Doench JG, Fortune SM, Lu TK. Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens. Cell Syst. 2020 09 23; 11(3):239-251.e7. PMID: 32970993.
    Citations: 4     Fields:    Translation:HumansCells
  21. Diedrich CR, Rutledge T, Maiello P, Baranowski TM, White AG, Borish HJ, Karell P, Hopkins F, Brown J, Fortune SM, Flynn JL, Ambrose Z, Lin PL. SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis. PLoS Pathog. 2020 07; 16(7):e1008413. PMID: 32730321; PMCID: PMC7419014.
    Citations: 14     Fields:    Translation:AnimalsCells
  22. Liu Q, Wei J, Li Y, Wang M, Su J, Lu Y, López MG, Qian X, Zhu Z, Wang H, Gan M, Jiang Q, Fu YX, Takiff HE, Comas I, Li F, Lu X, Fortune SM, Gao Q. Mycobacterium tuberculosis clinical isolates carry mutational signatures of host immune environments. Sci Adv. 2020 05; 6(22):eaba4901. PMID: 32524000; PMCID: PMC7259932.
    Citations: 9     Fields:    
  23. van Woudenbergh E, Irvine EB, Davies L, de Kock M, Hanekom WA, Day CL, Fortune S, Alter G. HIV Is Associated with Modified Humoral Immune Responses in the Setting of HIV/TB Coinfection. mSphere. 2020 05 20; 5(3). PMID: 32434838.
    Citations: 4     Fields:    Translation:HumansCells
  24. Ziegler CGK, Allon SJ, Nyquist SK, Mbano IM, Miao VN, Tzouanas CN, Cao Y, Yousif AS, Bals J, Hauser BM, Feldman J, Muus C, Wadsworth MH, Kazer SW, Hughes TK, Doran B, Gatter GJ, Vukovic M, Taliaferro F, Mead BE, Guo Z, Wang JP, Gras D, Plaisant M, Ansari M, Angelidis I, Adler H, Sucre JMS, Taylor CJ, Lin B, Waghray A, Mitsialis V, Dwyer DF, Buchheit KM, Boyce JA, Barrett NA, Laidlaw TM, Carroll SL, Colonna L, Tkachev V, Peterson CW, Yu A, Zheng HB, Gideon HP, Winchell CG, Lin PL, Bingle CD, Snapper SB, Kropski JA, Theis FJ, Schiller HB, Zaragosi LE, Barbry P, Leslie A, Kiem HP, Flynn JL, Fortune SM, Berger B, Finberg RW, Kean LS, Garber M, Schmidt AG, Lingwood D, Shalek AK, Ordovas-Montanes J. SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell. 2020 05 28; 181(5):1016-1035.e19. PMID: 32413319; PMCID: PMC7252096.
    Citations: 986     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  25. Tang S, Hicks ND, Cheng YS, Silva A, Fortune SM, Sacchettini JC. Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor. Nucleic Acids Res. 2019 10 10; 47(18):9934-9949. PMID: 31504787; PMCID: PMC6765138.
    Citations: 3     Fields:    Translation:Cells
  26. Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, Fortune SM, Seshadri C, Alter G. Publisher Correction: IFN-?-independent immune markers of Mycobacterium tuberculosis exposure. Nat Med. 2019 Jul; 25(7):1175. PMID: 31222179.
    Citations: 1     Fields:    
  27. Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, Brynildsen MP, Bumann D, Camilli A, Collins JJ, Dehio C, Fortune S, Ghigo JM, Hardt WD, Harms A, Heinemann M, Hung DT, Jenal U, Levin BR, Michiels J, Storz G, Tan MW, Tenson T, Van Melderen L, Zinkernagel A. Definitions and guidelines for research on antibiotic persistence. Nat Rev Microbiol. 2019 07; 17(7):441-448. PMID: 30980069; PMCID: PMC7136161.
    Citations: 236     Fields:    Translation:Cells
  28. Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, Brynildsen MP, Bumann D, Camilli A, Collins JJ, Dehio C, Fortune S, Ghigo JM, Hardt WD, Harms A, Heinemann M, Hung DT, Jenal U, Levin BR, Michiels J, Storz G, Tan MW, Tenson T, Van Melderen L, Zinkernagel A. Publisher Correction: Definitions and guidelines for research on antibiotic persistence. Nat Rev Microbiol. 2019 Jul; 17(7):460. PMID: 31036919.
    Citations: 8     Fields:    
  29. Carey AF, Rock JM, Krieger IV, Chase MR, Fernandez-Suarez M, Gagneux S, Sacchettini JC, Ioerger TR, Fortune SM. Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. PLoS Pathog. 2019 Jun; 15(6):e1007846. PMID: 31163081; PMCID: PMC6548391.
    Citations: 1     Fields:    
  30. Farhat MR, Sixsmith J, Calderon R, Hicks ND, Fortune SM, Murray M. Rifampicin and rifabutin resistance in 1003 Mycobacterium tuberculosis clinical isolates. J Antimicrob Chemother. 2019 06 01; 74(6):1477-1483. PMID: 30793747.
    Citations: 11     Fields:    Translation:HumansCells
  31. Bryson BD, Rosebrock TR, Tafesse FG, Itoh CY, Nibasumba A, Babunovic GH, Corleis B, Martin C, Keegan C, Andrade P, Realegeno S, Kwon D, Modlin RL, Fortune SM. Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis. Nat Commun. 2019 05 27; 10(1):2329. PMID: 31133636.
    Citations: 22     Fields:    Translation:HumansCells
  32. Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, Fortune SM, Seshadri C, Alter G. IFN-?-independent immune markers of Mycobacterium tuberculosis exposure. Nat Med. 2019 06; 25(6):977-987. PMID: 31110348; PMCID: PMC6559862.
    Citations: 76     Fields:    Translation:HumansCells
  33. Hicks ND, Carey AF, Yang J, Zhao Y, Fortune SM. Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis. mBio. 2019 04 23; 10(2). PMID: 31015328.
    Citations: 13     Fields:    Translation:Cells
  34. Montoya DJ, Andrade P, Silva BJA, Teles RMB, Ma F, Bryson B, Sadanand S, Noel T, Lu J, Sarno E, Arnvig KB, Young D, Lahiri R, Williams DL, Fortune S, Bloom BR, Pellegrini M, Modlin RL. Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune Response. Cell Rep. 2019 03 26; 26(13):3574-3585.e3. PMID: 30917313.
    Citations: 19     Fields:    Translation:HumansCells
  35. Cadena AM, Hopkins FF, Maiello P, Carey AF, Wong EA, Martin CJ, Gideon HP, DiFazio RM, Andersen P, Lin PL, Fortune SM, Flynn JL. Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques. PLoS Pathog. 2018 10; 14(10):e1007305. PMID: 30312351; PMCID: PMC6200282.
    Citations: 31     Fields:    Translation:AnimalsCellsPHPublic Health
  36. Simmons JD, Stein CM, Seshadri C, Campo M, Alter G, Fortune S, Schurr E, Wallis RS, Churchyard G, Mayanja-Kizza H, Boom WH, Hawn TR. Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection. Nat Rev Immunol. 2018 09; 18(9):575-589. PMID: 29895826; PMCID: PMC6278832.
    Citations: 81     Fields:    Translation:HumansCells
  37. Hicks ND, Yang J, Zhang X, Zhao B, Grad YH, Liu L, Ou X, Chang Z, Xia H, Zhou Y, Wang S, Dong J, Sun L, Zhu Y, Zhao Y, Jin Q, Fortune SM. Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance. Nat Microbiol. 2018 09; 3(9):1032-1042. PMID: 30082724.
    Citations: 48     Fields:    Translation:HumansCells
  38. Gerrick ER, Barbier T, Chase MR, Xu R, François J, Lin VH, Szucs MJ, Rock JM, Ahmad R, Tjaden B, Livny J, Fortune SM. Small RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):6464-6469. PMID: 29871950; PMCID: PMC6016810.
    Citations: 27     Fields:    Translation:Cells
  39. Yang JD, Mott D, Sutiwisesak R, Lu YJ, Raso F, Stowell B, Babunovic GH, Lee J, Carpenter SM, Way SS, Fortune SM, Behar SM. Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. PLoS Pathog. 2018 02; 14(5):e1007060. PMID: 29782535; PMCID: PMC6013218.
    Citations: 32     Fields:    Translation:AnimalsCells
  40. Sakatos A, Babunovic GH, Chase MR, Dills A, Leszyk J, Rosebrock T, Bryson B, Fortune SM. Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria. Sci Adv. 2018 05; 4(5):eaao1478. PMID: 29732401.
    Citations: 25     Fields:    Translation:Cells
  41. Keegan C, Krutzik S, Schenk M, Scumpia PO, Lu J, Pang YLJ, Russell BS, Lim KS, Shell S, Prestwich E, Su D, Elashoff D, Hershberg RM, Bloom BR, Belisle JT, Fortune S, Dedon PC, Pellegrini M, Modlin RL. Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. J Immunol. 2018 05 01; 200(9):3244-3258. PMID: 29610140; PMCID: PMC5916334.
    Citations: 7     Fields:    Translation:HumansCells
  42. Carey AF, Rock JM, Krieger IV, Chase MR, Fernandez-Suarez M, Gagneux S, Sacchettini JC, Ioerger TR, Fortune SM. TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. PLoS Pathog. 2018 03; 14(3):e1006939. PMID: 29505613.
    Citations: 33     Fields:    Translation:HumansCells
  43. Rubin EJ, Fortune SM. Misunderstanding the goals of animal research. BMJ. 2018 02 21; 360:k759. PMID: 29467126.
    Citations:    Fields:    Translation:Animals
  44. Franchina FA, Mellors TR, Aliyeva M, Wagner J, Daphtary N, Lundblad LKA, Fortune SM, Rubin EJ, Hill JE. Towards the use of breath for detecting mycobacterial infection: a case study in a murine model. J Breath Res. 2018 02 07; 12(2):026008. PMID: 29219122.
    Citations: 5     Fields:    Translation:AnimalsCells
  45. Lu LL, Suscovich TJ, Fortune SM, Alter G. Beyond binding: antibody effector functions in infectious diseases. Nat Rev Immunol. 2018 01; 18(1):46-61. PMID: 29063907; PMCID: PMC6369690.
    Citations: 204     Fields:    Translation:Humans
  46. Kurthkoti K, Amin H, Marakalala MJ, Ghanny S, Subbian S, Sakatos A, Livny J, Fortune SM, Berney M, Rodriguez GM. The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas. mBio. 2017 08 15; 8(4). PMID: 28811344.
    Citations: 45     Fields:    Translation:HumansCells
  47. Cadena AM, Fortune SM, Flynn JL. Heterogeneity in tuberculosis. Nat Rev Immunol. 2017 Nov; 17(11):691-702. PMID: 28736436; PMCID: PMC6247113.
    Citations: 147     Fields:    Translation:HumansAnimalsCells
  48. Martin CJ, Cadena AM, Leung VW, Lin PL, Maiello P, Hicks N, Chase MR, Flynn JL, Fortune SM. Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis. mBio. 2017 05 09; 8(3). PMID: 28487426.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  49. Gierahn TM, Wadsworth MH, Hughes TK, Bryson BD, Butler A, Satija R, Fortune S, Love JC, Shalek AK. Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput. Nat Methods. 2017 Apr; 14(4):395-398. PMID: 28192419; PMCID: PMC5376227.
    Citations: 282     Fields:    Translation:HumansAnimalsCells
  50. Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM. Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform. Nat Microbiol. 2017 Feb 06; 2:16274. PMID: 28165460.
    Citations: 128     Fields:    Translation:Cells
  51. DeJesus MA, Gerrick ER, Xu W, Park SW, Long JE, Boutte CC, Rubin EJ, Schnappinger D, Ehrt S, Fortune SM, Sassetti CM, Ioerger TR. Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis. mBio. 2017 01 17; 8(1). PMID: 28096490.
    Citations: 209     Fields:    Translation:Cells
  52. Warner DF, Rock JM, Fortune SM, Mizrahi V. DNA Replication Fidelity in the Mycobacterium tuberculosis Complex. Adv Exp Med Biol. 2017; 1019:247-262. PMID: 29116639.
    Citations: 3     Fields:    Translation:HumansCells
  53. Lu LL, Chung AW, Rosebrock TR, Ghebremichael M, Yu WH, Grace PS, Schoen MK, Tafesse F, Martin C, Leung V, Mahan AE, Sips M, Kumar MP, Tedesco J, Robinson H, Tkachenko E, Draghi M, Freedberg KJ, Streeck H, Suscovich TJ, Lauffenburger DA, Restrepo BI, Day C, Fortune SM, Alter G. A Functional Role for Antibodies in Tuberculosis. Cell. 2016 Oct 06; 167(2):433-443.e14. PMID: 27667685.
    Citations: 210     Fields:    Translation:HumansCells
  54. Lin PL, Maiello P, Gideon HP, Coleman MT, Cadena AM, Rodgers MA, Gregg R, O'Malley M, Tomko J, Fillmore D, Frye LJ, Rutledge T, DiFazio RM, Janssen C, Klein E, Andersen PL, Fortune SM, Flynn JL. PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis. PLoS Pathog. 2016 07; 12(7):e1005739. PMID: 27379816.
    Citations: 53     Fields:    Translation:AnimalsCells
  55. Kaufmann SH, Fortune S, Pepponi I, Ruhwald M, Schrager LK, Ottenhoff TH. TB biomarkers, TB correlates and human challenge models: New tools for improving assessment of new TB vaccines. Tuberculosis (Edinb). 2016 08; 99 Suppl 1:S8-S11. PMID: 27402312.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  56. Boutte CC, Baer CE, Papavinasasundaram K, Liu W, Chase MR, Meniche X, Fortune SM, Sassetti CM, Ioerger TR, Rubin EJ. A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis. Elife. 2016 06 15; 5. PMID: 27304077.
    Citations: 36     Fields:    Translation:Cells
  57. Lahiri N, Shah RR, Layre E, Young D, Ford C, Murray MB, Fortune SM, Moody DB. Rifampin Resistance Mutations Are Associated with Broad Chemical Remodeling of Mycobacterium tuberculosis. J Biol Chem. 2016 Jul 01; 291(27):14248-14256. PMID: 27226566.
    Citations: 19     Fields:    Translation:Cells
  58. Ma S, Bryson BD, Sun C, Fortune SM, Lu C. RNA Extraction from a Mycobacterium under Ultrahigh Electric Field Intensity in a Microfluidic Device. Anal Chem. 2016 05 17; 88(10):5053-7. PMID: 27081872; PMCID: PMC4872636.
    Citations: 4     Fields:    Translation:Cells
  59. Cadena AM, Flynn JL, Fortune SM. The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome. mBio. 2016 Apr 05; 7(2):e00342-16. PMID: 27048801.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  60. Grad YH, Fortune SM. Biodiversity and hypervirulence of Listeria monocytogenes. Nat Genet. 2016 Mar; 48(3):229-30. PMID: 26906682.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  61. Martin CJ, Carey AF, Fortune SM. A bug's life in the granuloma. Semin Immunopathol. 2016 Mar; 38(2):213-20. PMID: 26577238.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  62. Shell SS, Wang J, Lapierre P, Mir M, Chase MR, Pyle MM, Gawande R, Ahmad R, Sarracino DA, Ioerger TR, Fortune SM, Derbyshire KM, Wade JT, Gray TA. Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape. PLoS Genet. 2015 Nov; 11(11):e1005641. PMID: 26536359.
    Citations: 100     Fields:    Translation:Cells
  63. Kieser KJ, Boutte CC, Kester JC, Baer CE, Barczak AK, Meniche X, Chao MC, Rego EH, Sassetti CM, Fortune SM, Rubin EJ. Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria. PLoS Pathog. 2015 Jun; 11(6):e1005010. PMID: 26114871.
    Citations: 42     Fields:    Translation:Cells
  64. Datta P, Ravi J, Guerrini V, Chauhan R, Neiditch MB, Shell SS, Fortune SM, Hancioglu B, Igoshin OA, Gennaro ML. The Psp system of Mycobacterium tuberculosis integrates envelope stress-sensing and envelope-preserving functions. Mol Microbiol. 2015 Aug; 97(3):408-22. PMID: 25899163; PMCID: PMC4642893.
    Citations: 21     Fields:    Translation:Cells
  65. Rock JM, Lang UF, Chase MR, Ford CB, Gerrick ER, Gawande R, Coscolla M, Gagneux S, Fortune SM, Lamers MH. DNA replication fidelity in Mycobacterium tuberculosis is mediated by an ancestral prokaryotic proofreader. Nat Genet. 2015 Jun; 47(6):677-81. PMID: 25894501; PMCID: PMC4449270.
    Citations: 27     Fields:    Translation:Cells
  66. Gideon HP, Phuah J, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL. Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. PLoS Pathog. 2015 Jan; 11(1):e1004603. PMID: 25611466.
    Citations: 135     Fields:    Translation:HumansAnimalsCells
  67. Shell SS, Chase MR, Ioerger TR, Fortune SM. RNA sequencing for transcript 5'-end mapping in mycobacteria. Methods Mol Biol. 2015; 1285:31-45. PMID: 25779309.
    Citations: 6     Fields:    Translation:Cells
  68. Aldridge BB, Keren I, Fortune SM. The Spectrum of Drug Susceptibility in Mycobacteria. Microbiol Spectr. 2014 Oct; 2(5). PMID: 26104360.
    Citations: 13     Fields:    Translation:Cells
  69. Ramsdell TL, Huppert LA, Sysoeva TA, Fortune SM, Burton BM. Linked domain architectures allow for specialization of function in the FtsK/SpoIIIE ATPases of ESX secretion systems. J Mol Biol. 2015 Mar 13; 427(5):1119-32. PMID: 24979678.
    Citations: 13     Fields:    Translation:Cells
  70. Huppert LA, Ramsdell TL, Chase MR, Sarracino DA, Fortune SM, Burton BM. The ESX system in Bacillus subtilis mediates protein secretion. PLoS One. 2014; 9(5):e96267. PMID: 24798022.
    Citations: 24     Fields:    Translation:Cells
  71. Layre E, Lee HJ, Young DC, Martinot AJ, Buter J, Minnaard AJ, Annand JW, Fortune SM, Snider BB, Matsunaga I, Rubin EJ, Alber T, Moody DB. Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proc Natl Acad Sci U S A. 2014 Feb 25; 111(8):2978-83. PMID: 24516143.
    Citations: 36     Fields:    Translation:Cells
  72. Lin PL, Ford CB, Coleman MT, Myers AJ, Gawande R, Ioerger T, Sacchettini J, Fortune SM, Flynn JL. Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nat Med. 2014 Jan; 20(1):75-9. PMID: 24336248.
    Citations: 227     Fields:    Translation:AnimalsCells
  73. Kester JC, Fortune SM. Persisters and beyond: mechanisms of phenotypic drug resistance and drug tolerance in bacteria. Crit Rev Biochem Mol Biol. 2014 Mar-Apr; 49(2):91-101. PMID: 24328927.
    Citations: 67     Fields:    Translation:HumansCells
  74. Shell SS, Prestwich EG, Baek SH, Shah RR, Sassetti CM, Dedon PC, Fortune SM. DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis. PLoS Pathog. 2013; 9(7):e1003419. PMID: 23853579.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  75. Ford CB, Shah RR, Maeda MK, Gagneux S, Murray MB, Cohen T, Johnston JC, Gardy J, Lipsitch M, Fortune SM. Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis. Nat Genet. 2013 Jul; 45(7):784-90. PMID: 23749189.
    Citations: 189     Fields:    Translation:HumansCells
  76. Ragheb MN, Ford CB, Chase MR, Lin PL, Flynn JL, Fortune SM. The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosis from cynomolgus macaque infection. BMC Genomics. 2013 Mar 05; 14:145. PMID: 23496945.
    Citations: 9     Fields:    Translation:AnimalsCells
  77. Chao MC, Kieser KJ, Minami S, Mavrici D, Aldridge BB, Fortune SM, Alber T, Rubin EJ. Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria. PLoS Pathog. 2013 Feb; 9(2):e1003197. PMID: 23468634.
    Citations: 23     Fields:    Translation:Cells
  78. Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H, Weissleder R. Magnetic barcode assay for genetic detection of pathogens. Nat Commun. 2013; 4:1752. PMID: 23612293.
    Citations: 38     Fields:    Translation:HumansCells
  79. Fong EJ, Sharma Y, Fallica B, Tierney DB, Fortune SM, Zaman MH. Decoupling directed and passive motion in dynamic systems: particle tracking microrheology of sputum. Ann Biomed Eng. 2013 Apr; 41(4):837-46. PMID: 23271563.
    Citations:    Fields:    Translation:Humans
  80. De Leon J, Jiang G, Ma Y, Rubin E, Fortune S, Sun J. Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis. J Biol Chem. 2012 Dec 28; 287(53):44184-91. PMID: 23150662.
    Citations: 56     Fields:    Translation:Cells
  81. Fortune SM. The surprising diversity of Mycobacterium tuberculosis: change you can believe in. J Infect Dis. 2012 Dec 01; 206(11):1642-4. PMID: 22984117.
    Citations: 5     Fields:    Translation:HumansCells
  82. Martin CJ, Booty MG, Rosebrock TR, Nunes-Alves C, Desjardins DM, Keren I, Fortune SM, Remold HG, Behar SM. Efferocytosis is an innate antibacterial mechanism. Cell Host Microbe. 2012 Sep 13; 12(3):289-300. PMID: 22980326.
    Citations: 129     Fields:    Translation:AnimalsCells
  83. Lee HJ, Lang PT, Fortune SM, Sassetti CM, Alber T. Cyclic AMP regulation of protein lysine acetylation in Mycobacterium tuberculosis. Nat Struct Mol Biol. 2012 Aug; 19(8):811-8. PMID: 22773105.
    Citations: 31     Fields:    Translation:Cells
  84. Wirth SE, Krywy JA, Aldridge BB, Fortune SM, Fernandez-Suarez M, Gray TA, Derbyshire KM. Polar assembly and scaffolding proteins of the virulence-associated ESX-1 secretory apparatus in mycobacteria. Mol Microbiol. 2012 Feb; 83(3):654-64. PMID: 22233444.
    Citations: 15     Fields:    Translation:Cells
  85. Ford C, Yusim K, Ioerger T, Feng S, Chase M, Greene M, Korber B, Fortune S. Mycobacterium tuberculosis--heterogeneity revealed through whole genome sequencing. Tuberculosis (Edinb). 2012 May; 92(3):194-201. PMID: 22218163.
    Citations: 39     Fields:    Translation:HumansCells
  86. Aldridge BB, Fernandez-Suarez M, Heller D, Ambravaneswaran V, Irimia D, Toner M, Fortune SM. Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. Science. 2012 Jan 06; 335(6064):100-4. PMID: 22174129.
    Citations: 176     Fields:    Translation:Cells
  87. Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R. Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. Bioconjug Chem. 2011 Dec 21; 22(12):2390-4. PMID: 22043803.
    Citations: 21     Fields:    Translation:HumansCells
  88. Sillé FC, Martin C, Jayaraman P, Rothchild A, Fortune S, Besra GS, Behar SM, Boes M. Requirement for invariant chain in macrophages for Mycobacterium tuberculosis replication and CD1d antigen presentation. Infect Immun. 2011 Aug; 79(8):3053-63. PMID: 21576321.
    Citations: 6     Fields:    Translation:AnimalsCells
  89. Ford CB, Lin PL, Chase MR, Shah RR, Iartchouk O, Galagan J, Mohaideen N, Ioerger TR, Sacchettini JC, Lipsitch M, Flynn JL, Fortune SM. Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection. Nat Genet. 2011 May; 43(5):482-6. PMID: 21516081.
    Citations: 196     Fields:    Translation:HumansAnimalsCells
  90. Millington KA, Fortune SM, Low J, Garces A, Hingley-Wilson SM, Wickremasinghe M, Kon OM, Lalvani A. Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 2011 Apr 05; 108(14):5730-5. PMID: 21427227.
    Citations: 66     Fields:    Translation:HumansCells
  91. Woodworth JS, Shin D, Volman M, Nunes-Alves C, Fortune SM, Behar SM. Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination. J Immunol. 2011 Feb 01; 186(3):1627-37. PMID: 21178003; PMCID: PMC3133636.
    Citations: 20     Fields:    Translation:AnimalsCells
  92. Fortune SM, Rubin EJ. Host transcription in active and latent tuberculosis. Genome Biol. 2010; 11(9):135. PMID: 20920149.
    Citations: 1     Fields:    Translation:HumansCells
  93. Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, Ramsdell TL, Lopez MF, Behar SM, Sarracino DA, Fortune SM. EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. PLoS Pathog. 2010 Jun 24; 6(6):e1000957. PMID: 20585630.
    Citations: 49     Fields:    Translation:AnimalsCells
  94. Ioerger TR, Feng Y, Ganesula K, Chen X, Dobos KM, Fortune S, Jacobs WR, Mizrahi V, Parish T, Rubin E, Sassetti C, Sacchettini JC. Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories. J Bacteriol. 2010 Jul; 192(14):3645-53. PMID: 20472797.
    Citations: 120     Fields:    Translation:Cells
  95. Bitter W, Houben EN, Bottai D, Brodin P, Brown EJ, Cox JS, Derbyshire K, Fortune SM, Gao LY, Liu J, Gey van Pittius NC, Pym AS, Rubin EJ, Sherman DR, Cole ST, Brosch R. Systematic genetic nomenclature for type VII secretion systems. PLoS Pathog. 2009 Oct; 5(10):e1000507. PMID: 19876390.
    Citations: 130     Fields:    Translation:Cells
  96. Siegrist MS, Unnikrishnan M, McConnell MJ, Borowsky M, Cheng TY, Siddiqi N, Fortune SM, Moody DB, Rubin EJ. Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18792-7. PMID: 19846780.
    Citations: 154     Fields:    Translation:AnimalsCells
  97. Pandey AK, Yang Y, Jiang Z, Fortune SM, Coulombe F, Behr MA, Fitzgerald KA, Sassetti CM, Kelliher MA. NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis. PLoS Pathog. 2009 Jul; 5(7):e1000500. PMID: 19578435; PMCID: PMC2698121.
    Citations: 133     Fields:    Translation:AnimalsCells
  98. Divangahi M, Chen M, Gan H, Desjardins D, Hickman TT, Lee DM, Fortune S, Behar SM, Remold HG. Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair. Nat Immunol. 2009 Aug; 10(8):899-906. PMID: 19561612.
    Citations: 170     Fields:    Translation:HumansAnimalsCells
  99. Atmakuri K, Fortune SM. Regulation of protein secretion by ... protein secretion? Cell Host Microbe. 2008 Sep 11; 4(3):190-1. PMID: 18779042.
    Citations: 2     Fields:    Translation:HumansCells
  100. Woodworth JS, Fortune SM, Behar SM. Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10. Infect Immun. 2008 Sep; 76(9):4199-205. PMID: 18591224.
    Citations: 23     Fields:    Translation:AnimalsCells
  101. Hett EC, Chao MC, Steyn AJ, Fortune SM, Deng LL, Rubin EJ. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol Microbiol. 2007 Nov; 66(3):658-68. PMID: 17919286.
    Citations: 66     Fields:    Translation:Cells
  102. Fortune SM, Rubin EJ. The complex relationship between mycobacteria and macrophages: it's not all bliss. Cell Host Microbe. 2007 Jul 12; 2(1):5-6. PMID: 18005712.
    Citations: 6     Fields:    Translation:AnimalsCells
  103. Joshi SM, Pandey AK, Capite N, Fortune SM, Rubin EJ, Sassetti CM. Characterization of mycobacterial virulence genes through genetic interaction mapping. Proc Natl Acad Sci U S A. 2006 Aug 01; 103(31):11760-5. PMID: 16868085; PMCID: PMC1544243.
    Citations: 84     Fields:    Translation:AnimalsCells
  104. Fortune SM, Chase MR, Rubin EJ. Dividing oceans into pools: strategies for the global analysis of bacterial genes. Microbes Infect. 2006 May; 8(6):1631-6. PMID: 16697239.
    Citations: 1     Fields:    Translation:Cells
  105. Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ. Mutually dependent secretion of proteins required for mycobacterial virulence. Proc Natl Acad Sci U S A. 2005 Jul 26; 102(30):10676-81. PMID: 16030141; PMCID: PMC1176248.
    Citations: 185     Fields:    Translation:AnimalsCells
  106. Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ, Ernst JD. Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms. J Immunol. 2004 May 15; 172(10):6272-80. PMID: 15128816.
    Citations: 87     Fields:    Translation:HumansAnimalsCells
  107. Wain J, Diem Nga LT, Kidgell C, James K, Fortune S, Song Diep T, Ali T, O Gaora P, Parry C, Parkhill J, Farrar J, White NJ, Dougan G. Molecular analysis of incHI1 antimicrobial resistance plasmids from Salmonella serovar Typhi strains associated with typhoid fever. Antimicrob Agents Chemother. 2003 Sep; 47(9):2732-9. PMID: 12936967.
    Citations: 36     Fields:    Translation:Cells
  108. Fortune SM, Kaelin CM, Gulizia JM, Daily JP. Cat scratch disease presenting as a breast mass. Obstet Gynecol. 2000 Jun; 95(6 Pt 2):1027. PMID: 10808015.
    Citations: 2     Fields:    Translation:Humans
  109. Cleary AM, Fortune SM, Yellin MJ, Chess L, Lederman S. Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells. J Immunol. 1995 Oct 01; 155(7):3329-37. PMID: 7561026.
    Citations: 16     Fields:    Translation:HumansCells
  110. Yellin MJ, Winikoff S, Fortune SM, Baum D, Crow MK, Lederman S, Chess L. Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation. J Leukoc Biol. 1995 Aug; 58(2):209-16. PMID: 7543921.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  111. Lederman S, Yellin MJ, Cleary AM, Fortune SM, Chess L. The understanding of contact-dependent T-cell helper function in molecular, cellular and physiological detail. Res Immunol. 1994 Mar-Apr; 145(3):215-21; discussion 244-9. PMID: 7527578.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: SPH faculty should contact Faculty Affairs at facultyaffairshsph.harvard.edu).
Fortune's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (448)
Co-Authors (57)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.