Harvard Catalyst Profiles

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Sarah Merritt Fortune, M.D.

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Columbia University, College of Physicians and SurgeonsM.D.1996Medicine
Yale UniversityB.S.1990Biology
HSPHPost Doc2006Immunology & Infectious Diseases - 5years Postdoctoral Fellow
Brigham and Women’s Hospital20003years Internship/Residency in Internal Medicine
Brigham and Women’s Hospital20011year Clinical Fellowship in Infectious Diseases


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 1P01AI143575-01A1 (RUBIN ERIC) Jun 12, 2020 - May 31, 2025
    Pathway Analysis in Tuberculosis
    Role Description: The goal of this project is to understand key pathways in Mtb biology using advanced genetic, genomic and biochemical methods, and the gold-standard in vitro and in vivo systems developed in our labs to mimic critical aspects of human TB.
    Role: Multi PI
  2. 75N93019C00071 (FORTUNE S.) Sep 1, 2019 - Sep 29, 2026
    Immune Mechanisms of Protection against Mycobacterium tuberculosis Center (IMPAc-TB)
    Role Description: The goal of this project is to apply the tools of systems immunology to exclusive animal and human models of protection from Mtb infection and disease progression.
    Role: Principal Investigator
  3. U19 AI142793 (MURRAY MEGAN) Apr 18, 2019 - Mar 31, 2024
    Bacterial Determinants of Treatment Response in Mycobacteria Tuberculosis
    Role Description: Effective control of drug-resistant TB requires the early diagnosis and treatment to prevent further transmission of the disease. Through this program, we aim to develop tools to detect drug resistant TB and improve patient outcomes.
    Role: Co-Investigator
  4. R01AI143788 (FLYNN JOANN) Feb 6, 2019 - Jan 31, 2024
    University of Pittsburgh/NIH/NIAID
    Development of a self-inactivating, highly effective TB vaccine
    Role Description: The goal of to generate and characterize candidate vaccine strains of M. bovis BCG that are conditionally replicating.
    Role: Co-Investigator
  5. R01 AI135629 (EHRT S. FORTUNE S.) Sep 1, 2018 - Aug 31, 2023
    Weill Medical College of Cornell University
    Conditionally replicating Mycobacterium tuberculosis vaccines
    Role Description: The goal of this project to develop and test candidate vaccine strains of Mycobacterium tuberculosis (Mtb), develop strains of Mtb that are dependent on an unnatural amino acid system for growth (i.e. the bacteria will not grow without the exogenous supplementation of an unnatural amino acid).
    Role: Co-Principal Investigator

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.